Yano Masashi 矢野雅司

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YANO Masashi 矢野雅司

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Researcher Number	10531858
Affiliation (Current)	2025: 徳島大学, 技術支援部蔵本技術部門, 技術支援職員
Affiliation (based on the past Project Information) *help	2016: 徳島大学, 先端酵素学研究所(次世代), 技術専門職員 2016: 徳島大学, 先端酵素学研究所, 技術専門職員 2013 – 2016: 徳島大学, 疾患酵素学研究センター, 技術員 2009 – 2010: The University of Tokushima, 疾患酵素学研究センター, 技術員
Review Section/Research Field	Principal Investigator Neurology / Pathological medical chemistry Except Principal Investigator Virology / Infectious disease medicine / Neurology
Keywords	Principal Investigator オートファジー / プリオン / AIRE / 胸腺 / 自己寛容 Except Principal Investigator プリオン蛋白質 / ノックアウトマウス / プリオン病 / プリオン / ソーティリン欠損細胞 … More / ンソーティリン欠損マウス / プリオン高感受性 / タパク質分解 / プリオン分解 / タンパク質分解 / レトロマー複合体 / プリオン感染 / ソーティリン / VPS35 / レトロマー / ソーティング / Sortilin / 異常プリオン / リード化合物 / 抗体 / 酸化ストレス / アポトーシス / 銅/亜鉛依存性スーパーオキシドジスムターゼ / 銅イオン / 活性酸素種 / インフルエンザウイルス / インフルエンザ / ポストゴルジ輸送 / Tgマウス / 細胞膜蛋白質 / 小胞輸送 / 神経変性 / ポストゴルジ小胞輸送 / インスリン受容体 / アトラクチン / トランスジェニックマウス / 神経変性疾患 / 蛋白質分解 / 蛋白質輸送 / ソーチリン Less

Elucidation of our recent findings on the protective role of prion protein against lethal infection with influenza A viruses is useful for development of a new type of anti-influenza drugs
- Principal Investigator
  
  SAKAGUCHI Suehiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Infectious disease medicine
- Research Institution
  The University of Tokushima
Elucidation of the vesicular trafficking mechanism for prion propagation on the basis of our previous findings of the disturbed vesicular trafficking in prion disease
- Principal Investigator
  
  SAKAGUCHI Suehiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokushima
Development of basic technology for therapy of prion diseases based on Sortilin function
- Principal Investigator
  
  UCHIYAMA Keiji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The University of Tokushima
Prion protein overexpress induces on autophagy mechanism explication.Principal Investigator
- Principal Investigator
  
  YANO Masashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokushima
Epigenetic approach to the elucidation of the molecular pathogenesis of autoimmune diseasePrincipal Investigator
- Principal Investigator
  
  YANO Masashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima

All 2017 2014 2011 2010 2009

All Journal Article Presentation

[Journal Article] Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.2017
- Author(s)
  Nandita Rani Das, Hironori Miyata, Hideyuki Hara, Keiji Uchiyama, Junji Chida, Masashi Yano, Hitomi Watanabe, Gen Kondoh, Suehiro Sakaguchi
- Journal Title
  
  Archives of Virology
  
  Volume: 印刷中 Issue: 7 Pages: 1867-1876
- DOI
  10.1007/s00705-017-3295-3
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01560, KAKENHI-PROJECT-26293212, KAKENHI-PROJECT-15K15380, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K10029, KAKENHI-PROJECT-17K08859
[Journal Article] Mouse-hamster chimeric prion protein (PrP) devoid of N-terminal residues 23-88 restores susceptibility to 22L prions, but not to RML prions in PrP-knockout mice.2014
- Author(s)
  Uchiyama K, Miyata H, Yano M, Yamaguchi Y, Imamura M, Muramatsu N, Das NR, Chida J, Hara H, Sakaguchi S.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 10 Pages: e109737-e109737
- DOI
  10.1371/journal.pone.0109737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870474, KAKENHI-PROJECT-25870479, KAKENHI-PROJECT-26460557
[Journal Article] Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.2011
- Author(s)
  Mouri Y, Yano M, Shinzawa M, Shimo Y, Hirota F, Nishikawa Y, Nii T, Kiyonari H, Abe T, Uehara H, Izumi K, Tamada K, Chen L, Penninger JM, Inoue J, Akiyama T, Matsumoto M.
- Journal Title
  
  J.Immunol. 186
  
  Pages: 5047-5057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790321
[Journal Article] Biphasic Aire expression in early embryos and in medullary thymic epithelial cells prior to end-stage terminal differentiation.2010
- Author(s)
  Nishikawa Y, Hirota F, Yano M, Kitajima H, Miyazaki J-i, Kawamoto H, Mouri Y, Matsumoto M.
- Journal Title
  
  J.Exp.Med. 207
  
  Pages: 963-971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790321
[Presentation] Aireは初期胚と終末分化初期にある胸腺髄質上皮細胞との2相性発現を示す2010
- Author(s)
  西川裕美子、廣田史子、矢野雅司、毛利安宏、松本満
- Organizer
  第9回四国免疫フォーラム
- Place of Presentation
  愛媛大学医学部、愛媛県東温市
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21790321
[Presentation] Roles of NIK in thymic epithelial cells for the establishment of central tolerance.2009
- Author(s)
  Mouri Y, Yano M, Matsumoto M.
- Organizer
  12th International TNF Conference
- Place of Presentation
  San Lorenzo de El Escorial, Madrid, Spain.
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-21790321
[Presentation] Roles of NIK in thymic epithelial cells for the establishment of central tolerance2009
- Author(s)
  Mouri, Y., Yano, M., Matsumoto, M.
- Organizer
  12^<th> International TNF Conference
- Place of Presentation
  San Lorenzo de El Escorial, Madrid, Spain
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-21790321

1. SAKAGUCHI Suehiro (60274635)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. UCHIYAMA Keiji (60294039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 千田淳司 (20437651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 原英之 (40469953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yano Masashi 矢野 雅司

YANO Masashi 矢野 雅司

Research Projects

Research Products

Co-Researchers

Elucidation of our recent findings on the protective role of prion protein against lethal infection with influenza A viruses is useful for development of a new type of anti-influenza drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the vesicular trafficking mechanism for prion propagation on the basis of our previous findings of the disturbed vesicular trafficking in prion disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of basic technology for therapy of prion diseases based on Sortilin function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prion protein overexpress induces on autophagy mechanism explication.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenetic approach to the elucidation of the molecular pathogenesis of autoimmune diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mouse-hamster chimeric prion protein (PrP) devoid of N-terminal residues 23-88 restores susceptibility to 22L prions, but not to RML prions in PrP-knockout mice.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.2011

Author(s)

Journal Title

Data Source

[Journal Article] Biphasic Aire expression in early embryos and in medullary thymic epithelial cells prior to end-stage terminal differentiation.2010

Author(s)

Journal Title

Data Source

[Presentation] Aireは初期胚と終末分化初期にある胸腺髄質上皮細胞との2相性発現を示す2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Roles of NIK in thymic epithelial cells for the establishment of central tolerance.2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Roles of NIK in thymic epithelial cells for the establishment of central tolerance2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Yano Masashi 矢野雅司

YANO Masashi 矢野雅司