LE THITHANHTHUY ＬＥＴＨＩＴＨＡＮＨＴＨＵＹ

… Alternative Names

Le Thi Thanh Thuy LE THITHANHTHUY

LE THUY LE THUY

Le Thuy レイトゥイ

LE Thuy

Less

Researcher Number	10572175
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 大阪公立大学, 大学院医学研究科, 准教授 2022 – 2023: 大阪公立大学, 大学院医学研究科, 特任講師 2019 – 2021: 大阪市立大学, 大学院医学研究科, 特任講師 2015 – 2018: 大阪市立大学, 大学院医学研究科, 特任助教 2014: 大阪市立大学, 医学(系)研究科(研究院), 助教 2013: 大阪市立大学, 医学(系)研究科(研究院), 研究員 2010 – 2011: 大阪市立大学, 大学院・医学研究科, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Carcinogenesis
Keywords	Principal Investigator Cytoglobin / Anti-fibrosis / Antioxidant / Liver fibrosis / Hepatic Stellate Cells / cytoglobin / Hepatic stellate cells / Hemoglobin / Myoglobin / Neuroglobin … More / Globin / Hepatocellular Carcinoma / Fibrosis / Hepatosteatosis / Liver cancer / 肝臓学 / ウイルス / cholestasis / fibrosis / hepatic stellate cells / liver fibrosis / HCC / Liver Fibrosis / OXIDATIVE STRESS / LIVER CANCER / LIVER FIBROSIS / NASH / HSCS / CYGB / ｻｲﾄｸﾞﾛﾋﾞﾝ / サイトグロビン / 遺伝子 … More Except Principal Investigator 肝線維化 / サイトグロビン / Cytoglobin / コラーゲン / 星細胞 / 食道静脈瘤 / HVPG / 慢性肝疾患 / 門脈圧亢進症 / TGFβ / ROS / TGF-β / 肝星細胞 / 肝硬変 / 肝がん / 線維芽細胞 / 免疫チェックポイント分子 / 免疫チェックポイント / インターフェロン / 核酸アナログ / 抗ウイルス治療 / B型肝炎 / pancreatic tumor / liver tumor / Demethylation / Promoter / Liver cancer / DAC / Huh-7 / Liver tumor / CYGB promoter / DNA methylation / 肝弾性度 / M2BPGi / 食道胃静脈瘤 / ヒドロキシラジカル / 非アルコール性脂肪肝炎 / 加齢 / 脂肪肝炎 / 老化 / NASH / 赤血球 / 血小板 / 肝臓学 / プロモーター / 発がん / 炎症 / 線維化 / α平滑筋アクチン / 動物モデル / 肝癌 / 間質細胞 / 自然発症 / 乳癌 / ビタミンA Less

慢性肝疾患において肝線維化が改善すると門脈圧は低下するか？その限界はどこか？
- Principal Investigator
  
  打田佐和子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
Novel anti-fibrotic properties of heme binding proteins including Neuroglobin, Myoglobin, and Hemoglobin in comparison with Cytoglobin in vitro and in vivoPrincipal Investigator
- Principal Investigator
  
  LE THITHANHTHUY
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
肝細胞のがん化における細胞間相互作用を介した星細胞の役割
- Principal Investigator
  
  河田則文
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
Cytoglobin (CYGB)-overexpression and targeted demethylation of CYGB promoter impair liver and pancreatic tumor growth
- Principal Investigator
  
  HOANG HAI
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
B型肝炎の治療抵抗性および病態進展における免疫チェックポイント分子の関与
- Principal Investigator
  
  榎本大
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Does portal pressure in chronic liver disease decrease as liver fibrosis improves?
- Principal Investigator
  
  Uchida-Kobayashi Sawako
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Cytoglobin overexpression inhibits liver fibrosis and cancer development via anti-oxidant functionPrincipal Investigator
- Principal Investigator
  
  Le Thi Thanh Thuy
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka City University
Are activated stellate cells producing Cytoglobin directly involved in hepatocarcinogenesis?
- Principal Investigator
  
  Kawada Norifumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka City University
Role of red blood cells and platelets in the development of chronic inflammation of nonalcoholic steatohepatitis
- Principal Investigator
  
  Fujii Hideki
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Development of anti-fibrotic therapy for liver disease by establishing technologies that regulate cytoglobin expression in hepatic stellate cells
- Principal Investigator
  
  KAWADA NORIFUMI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Protective role of CYGB in prevention of liver fibrosis development in vitro and in vivoPrincipal Investigator
- Principal Investigator
  
  LE THI THANH THUY
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Involvement of Cytoglobin expressed in hepatic stellate cells in the development of cancer derived from inflamed liver.
- Principal Investigator
  
  KAWADA NORIFUMI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Loss of Cytoglobin Exacerbates Liver Fibrosis and Cancer Development in Steatohepatitis by Activating the Oxidative Stress PathawayPrincipal Investigator
- Principal Investigator
  
  LE THUY
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Involvement of cytoglobin-expressing mesenchymal cells in cancer development
- Principal Investigator
  
  KAWADA Norifumi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Carcinogenesis
- Research Institution
  Osaka City University

[Book] The Evolving Landscape of Liver Cirrhosis Management. Chapter 16: Antifibrotic therapy for liver cirrhosis.2019
- Author(s)
  Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Ninh Quoc Dat, Dinh Viet Hoang, and Norifumi Kawada.
- Publisher
  Springer Nature Singapore Pte Ltd
- ISBN
  9789811379796
- Data Source
  KAKENHI-PROJECT-19K08428
[Book] The Evolving Landscape of Liver Cirrhosis Management. Chapter 16: Antifibrotic therapy for liver cirrhosis.2018
- Author(s)
  1.Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Ninh Quoc Dat, Dinh Viet Hoang, and Norifumi Kawada.
- Publisher
  Springer Nature Singapore Pte Ltd
- Data Source
  KAKENHI-PROJECT-16K19363
[Book] Liver Pathophysiology-Therapies and Antioxidants2017
- Author(s)
  Le Thi Thanh Thuy, Tuong Thi Van Thuy, Hoang Hai, Norifumi Kawada
- Total Pages
  869
- Publisher
  Mica Haley
- ISBN
  9780128042748
- Data Source
  KAKENHI-PROJECT-16K19363
[Book] Stress in Applied Basic Reserch and Clinical Practice. CHAPTER 18:Antioxidant Approach to the Therapy of Chronic Liver Diseases.2015
- Author(s)
  Le Thi Thanh Thuy,Hoang Hai,Norifumi Kawada
- Total Pages
  413
- Publisher
  Springer International Publishing Switzerland
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Transcriptomics of a cytoglobin knockout mouse: Insights from hepatic stellate cells and brain2024
- Author(s)
  Porto Elena、De Backer Joey、Thuy Le Thi Thanh、Kawada Norifumi、Hankeln Thomas
- Journal Title
  
  Journal of Inorganic Biochemistry
  
  Volume: 250 Pages: 112405-112405
- DOI
  10.1016/j.jinorgbio.2023.112405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-23K24322
[Journal Article] Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40?CD40L Linkage2024
- Author(s)
  Ngo Hanh Vinh、Thanh Le Thuy Thi、Vu Hieu Ngoc、Hoang Hai、Ikenaga Hiroko、Sato-Matsubara Misako、Uchida-Kobayashi Sawako、Urushima Hayato、Van Nguyen Khanh、Nguyen Ha Thi、Shinkawa Hiroji、Kubo Shoji、Ohtani Naoko、Enomoto Masaru、Tamori Akihiro、Kawada Norifumi
- Journal Title
  
  The American Journal of Pathology
  
  Volume: in press Issue: 7 Pages: 1230-1247
- DOI
  10.1016/j.ajpath.2024.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07921, KAKENHI-PROJECT-21K07990, KAKENHI-PROJECT-23K24322
[Journal Article] Global treatment rate and barriers to direct‐acting antiviral therapy: A systematic review and meta‐analysis of 146 studies and 1?760?352 hepatitis C virus patients2023
- Author(s)
  Nguyen VH, Huang DQ, Le MH, Jin M, Lee EY, Henry L, Nerurkar SN, Ogawa E, Thin KN, Teng MLP, Goh KS, Kai JCY, Wong C, Tan DJH, Thuy LTT, Hai H, Enomoto M, Cheung R, Nguyen MH
- Journal Title
  
  Liver International
  
  Volume: 43 Issue: 6 Pages: 1195-1203
- DOI
  10.1111/liv.15550
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07989, KAKENHI-PROJECT-22K08083
[Journal Article] In Vitro Models for the Study of Liver Biology and Diseases: Advances and Limitations.2023
- Author(s)
  Kaur S*, Kidambi S*, Ortega-Ribera M*, Thuy LTT*, Nieto N, Cogger V, Xie WF, Frank Tacke, Gracia-Sancho J
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 15 Issue: 3 Pages: 559-571
- DOI
  10.1016/j.jcmgh.2022.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24322, KAKENHI-PROJECT-22K08083
[Journal Article] Nitric Oxide Derived from Cytoglobin-Deficient Hepatic Stellate Cells Causes Suppression of Cytochrome c Oxidase Activity in Hepatocytes2023
- Author(s)
  Yoshinori Okina, Misako Sato-Matsubara, Yasutoshi Kido, Hayato Urushima, Atsuko Daikoku, Chiho Kadono, Yu Nakagama, Yuko Nitahara, Truong Huu Hoang, Le Thi Thanh Thuy, Tsutomu Matsubara, Naoko Ohtani, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada.
- Journal Title
  
  Antioxid Redox Signal.
  
  Volume: 38 Pages: 463-479
- DOI
  10.1089/ars.2021.0279
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-20H00335, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-23K21359, KAKENHI-PROJECT-21K06757, KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-23K24322
[Journal Article] Increased spine bone density in patients with chronic hepatitis B switched to tenofovir alafenamide: A prospective, multinational study2023
- Author(s)
  Ogawa E, Jun DW, Toyoda H, Hsu YC, Yoon EL, Ahn SB, Yeh ML, Do S, Trinh HN, Takahashi H, Enomoto M, Kawada N, Yasuda S, Tseng CH, Kawashima K, Lee HA, Inoue K, Haga H, Do AT, Maeda M, Hoang JH, Cheung R, Ueno Y, Eguchi Y, Furusyo N, Yu ML, Tanaka Y, Nguyen MH
- Journal Title
  
  Alimentary Pharmacology & Therapeutics
  
  Volume: 59 Issue: 2 Pages: 239-248
- DOI
  10.1111/apt.17785
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07989, KAKENHI-PROJECT-23K24322
[Journal Article] Real-world treatment outcome with protease inhibitor direct-acting antiviral in advanced hepatitis C cirrhosis: a REAL-C study.2023
- Author(s)
  Wong YJ, Tran S, Huang CF, Hsu YC, Preda C, Toyoda H, Liu J, Jun DW, Landis C, Huang DQ, Gila A, Negoita L, Yasuda S, Tseng CH, Tsai PC, Uojima H, Nozaki A, Chuma M, Atsukawa M, Ishigami M, Itokawa N, Iio E, Lam CP, Watanabe T, Asai A, Yokohama K, Abe H, Enomoto M, Kawada N, Tamori A, Lee DH, Jun MJ, et al.
- Journal Title
  
  Hepatol Int
  
  Volume: 1 Issue: 5 Pages: 110-1161
- DOI
  10.1007/s12072-023-10547-4
- Data Source
  KAKENHI-PROJECT-23K24322
[Journal Article] Collaborating with AI in literature search?An important frontier2023
- Author(s)
  Enomoto Masaru、Tseng Cheng-Hao、Hsu Yao-Chun、Thuy Le Thi Thanh、Nguyen Mindie H.
- Journal Title
  
  Hepatology Communications
  
  Volume: 7 Issue: 12
- DOI
  10.1097/hc9.0000000000000336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08083
[Journal Article] Progression Rates by Age, Sex, Treatment, and Disease Activity by AASLD and EASL Criteria: Data for Precision Medicine2022
- Author(s)
  Park J, Le AK, Tseng TC, Yeh ML, Jun DW, Trinh H, Wong GLH, Chen CH, Peng CY, Kim SE, Oh H, Kwak MS, Cheung KS, Toyoda H, Hsu YC, Jeong JY, Yoon EL, Ungtrakul T, Zhang J, Xie Q, Ahn SB, Enomoto M, … Nguyen MH.
- Journal Title
  
  Clinical Gastroenterology and Hepatology
  
  Volume: 20 Issue: 4 Pages: 874-885.e4
- DOI
  10.1016/j.cgh.2021.05.062
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07989
[Journal Article] Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species2022
- Author(s)
  Hoang Dinh Viet、Thuy Le Thi Thanh、Hai Hoang、Hieu Vu Ngoc、Kimura Kenjiro、Oikawa Daisuke、Ikura Yoshihiro、Dat Ninh Quoc、Hoang Truong Huu、Sato-Matsubara Misako、Dong Minh Phuong、Hanh Ngo Vinh、Uchida-Kobayashi Sawako、Tokunaga Fuminori、Kubo Shoji、Ohtani Naoko、Yoshizato Katsutoshi、Kawada Norifumi
- Journal Title
  
  Oncogenesis
  
  Volume: 11 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41389-022-00389-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07921, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21H03369, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-23K24322
[Journal Article] Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms.2022
- Author(s)
  Huu Hoang T, Sato-Matsubara M, Yuasa H, Matsubara T, Thuy LTT, Ikenaga H, Phuong DM, Hanh NV, Hieu VN, Hoang DV, Hai H, Okina Y, Enomoto M, Tamori A, Daikoku A, Urushima H, Ikeda K, Dat NQ, Yasui Y, Shinkawa H, Kubo S, Yamagishi R, Ohtani N, Yoshizato K, Gracia-Sancho J, Kawada N.
- Journal Title
  
  Sci Adv.
  
  Volume: 8(39) Issue: 39 Pages: 5525-5525
- DOI
  10.1126/sciadv.abo5525
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06757, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-21K07990, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-23K21359, KAKENHI-PROJECT-23K24322
[Journal Article] Soluble programmed cell death-1 predicts hepatocellular carcinoma development during nucleoside analogue treatment.2022
- Author(s)
  Ritsuzo Kozuka, Masaru Enomoto, Minh Phuong Dong, Hoang Hai, Le Thi Thanh Thuy, Naoshi Odagiri, Kanako Yoshida, Kohei Kotani, Hiroyuki Motoyama, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii, Sawako Uchida-Kobayashi, Akihiro Tamori, Norifumi Kawada
- Journal Title
  
  Scientific reports
  
  Volume: 12 Issue: 1 Pages: 105-105
- DOI
  10.1038/s41598-021-03706-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15792, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-21K07989, KAKENHI-PROJECT-21K07990
[Journal Article] Soluble Immune Checkpoint Protein CD27 Is a Novel Prognostic Biomarker of Hepatocellular Carcinoma Development in Hepatitis C Virus?Sustained Virological Response Patients2022
- Author(s)
  Dong Minh Phuong、Thuy Le Thi Thanh、Hoang Dinh Viet、Hai Hoang、Hoang Truong Huu、Sato-Matsubara Misako、Hieu Vu Ngoc、Daikoku Atsuko、Hanh Ngo Vinh、Urushima Hayato、Dat Ninh Quoc、Uchida-Kobayashi Sawako、Enomoto Masaru、Ohtani Naoko、Tamori Akihiro、Kawada Norifumi
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 192 Issue: 10 Pages: 1379-1396
- DOI
  10.1016/j.ajpath.2022.07.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07921, KAKENHI-PROJECT-21K07990, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-23K24322
[Journal Article] Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion.2022
- Author(s)
  Hieu VN, Thuy LTT, Hai H, Dat NQ, Hoang DV, Hanh NV, Phuong DM, Hoang TH, Sawai H, Shiro Y, Sato-Matsubara M, Oikawa D, Tokunaga F, Yoshizato K, Kawada N.
- Journal Title
  
  Redox Biol.
  
  Volume: 52 Pages: 102286-102286
- DOI
  10.1016/j.redox.2022.102286
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02688, KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-23K24322
[Journal Article] Cytoglobin expression in pericyte and its role in pancreatic cancer.2021
- Author(s)
  Thuy le TT, Hai H, Dinh VH, Ngo VH, Uchida-Kobayashi S, Kawada N.
- Journal Title
  
  Gastroenterology & Hepatology
  
  Volume: 10 Pages: 354-362
- Data Source
  KAKENHI-PROJECT-19H03641
[Journal Article] 【膵癌研究最前線】膵星細胞に発現するサイトグロビンの膵癌における役割2021
- Author(s)
  Le Thi Thanh Thuy、Hoang Hai、Dinh Viet Hoang、Ngo Vinh Hanh、打田佐和子（小林）、河田則文
- Journal Title
  
  消化器・肝臓内科
  
  Volume: 10 Pages: 354-362
- Data Source
  KAKENHI-PROJECT-19H03641
[Journal Article] Cytoglobin expression in pericyte and its role in pancreatic cancer2021
- Author(s)
  1.Thuy le TT, Hai H, Dinh VH, Ngo VH, Uchida-Kobayashi S, Kawada N
- Journal Title
  
  Gastroenterology & Hepatology
  
  Volume: 10 (3) Pages: 354-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08428
[Journal Article] Incidences and Determinants of Functional Cure During Entecavir or Tenofovir Disoproxil Fumarate for Chronic Hepatitis B2021
- Author(s)
  Hsu Yao-Chun、Yeh Ming-Lun、Wong Grace Lai-Hung、Chen Chien-Hung、Peng Cheng-Yuan、Buti Maria、Enomoto Masaru、Xie Qing、Trinh Huy、Preda Carmen、Liu Li、Cheung Ka-Shing、Yeo Yee Hui、Hoang Joseph、Huang Chung-Feng、Riveiro-Barciela Mar、Kozuka Ritsuzo、Istratescu Doina、Tsai Pei-Chien、Accarino Elena Vargas、et al.
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 224 Issue: 11 Pages: 1890-1899
- DOI
  10.1093/infdis/jiab241
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07989
[Journal Article] 6His-tagged Recombinant Human Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species2021
- Author(s)
  Ninh Quoc Dat, Le Thi Thanh Thuy, Vu Ngoc Hieu, Fuminori Tokunaga, Massimo Pinzani, and Norifumi Kawada
- Journal Title
  
  Hepatology
  
  Volume: 0-0 Issue: 6 Pages: 0-0
- DOI
  10.1002/hep.31752
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-18K07952, KAKENHI-PROJECT-19K22541, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-16H06276
[Journal Article] On‐treatment gamma‐glutamyl transferase predicts the development of hepatocellular carcinoma in chronic hepatitis B patients2021
- Author(s)
  Huang Chung‐Feng、Jang Tyng‐Yuan、Jun Dae Won、Ahn Sang Bong、An Jihyun、Enomoto Masaru、Takahashi Hirokazu、Ogawa Eiichi、Yoon Eileen、Jeong Soung Won、Shim Jae‐Jun、Jeong Jae Yoon、Kim Sung Eun、Oh Hyunwoo、Kim Hyoung Su、Cho Yong Kyun、Kozuka Ritsuzo、Inoue Kaori、Cheung Ka Shing、Mak Lung Yi、et al.
- Journal Title
  
  Liver International
  
  Volume: 42 Issue: 1 Pages: 59-68
- DOI
  10.1111/liv.15085
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07989
[Journal Article] Hepatocellular carcinoma incidence with tenofovir versus entecavir in chronic hepatitis B: a systematic review and meta-analysis.2020
- Author(s)
  3.Cheng-Hao Tseng, Yao-Chun Hsu, Tzu-Haw Chen, Fanpu Ji, I-Sung Chen, Ying-Nan Tsai, Hoang Hai, Le Thi Thanh Thuy, Tetsuya Hosaka, Hitomi Sezaki, John A Borghi, Ramsey Cheung, Masaru Enomoto, Mindie H Nguyen
- Journal Title
  
  Lancet Gastroenterol Hepatol
  
  Volume: 5 Issue: 12 Pages: 1039-1052
- DOI
  10.1016/s2468-1253(20)30249-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08428
[Journal Article] Role of Cytoglobin, a Novel Radical Scavenger, in Stellate Cell Activation and Hepatic Fibrosis.2020
- Author(s)
  Le Thi Thanh Thuy, Hoang Hai, and Norifumi Kawada
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: - Issue: 3 Pages: 280-293
- DOI
  10.3350/cmh.2020.0037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Journal Article] The anti-oxidative role of cytoglobin in podocytes: implications for a role in chronic kidney disease2020
- Author(s)
  Elisa B. Randi, Vervaet Benjamin, Maria Tsachaki, Elena Porto, Stijn Vermeylen, Maja T. Lindenmeyer, Le Thi Thanh Thuy, Clemens D. Cohen, Olivier Devuyst, Andreas Kistler, Csaba Szabo, Norifumi Kawada, Thomas Hankeln, Alex Odermatt, Sylvia Dewilde, Roland H. Wenger, David Hoogewijs.
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: 7 Issue: 16 Pages: 1155-1171
- DOI
  10.1089/ars.2019.7868
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Journal Article] Changes in plasma interleukin-8 and tumor necrosis factor-α levels during the early treatment period as a predictor of the response to sorafenib in patients with unresectable hepatocellular carcinoma2018
- Author(s)
  Iida-Ueno Ayako、Enomoto Masaru、Uchida-Kobayashi Sawako、Hagihara Atsushi、Teranishi Yuga、Fujii Hideki、Morikawa Hiroyasu、Murakami Yoshiki、Tamori Akihiro、Thuy Le Thi Thanh、Kawada Norifumi
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 82 Issue: 5 Pages: 857-864
- DOI
  10.1007/s00280-018-3681-x
- Data Source
  KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-16K19363
[Journal Article] Selective overexpression of cytoglobin in stellate cells attenuates thioacetamide-induced liver fibrosis in mice.2018
- Author(s)
  Thi Thanh Hai N, Thuy LTT, Shiota A, Kadono C, Daikoku A, Hoang DV, Dat NQ, Sato-Matsubara M, Yoshizato K, Kawada N.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 17860-17860
- DOI
  10.1038/s41598-018-36215-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-16K19363
[Journal Article] Cytoglobin Regulates Blood Pressure and Vascular Tone through Nitric Oxide Metabolism in the Vascular Wall.2017
- Author(s)
  4.Xiaoping Liu, Mohamed A. El-Mahdy, James Boslett, Saradhadevi Varadharaj, Craig, Hemann, Tamer M. Abdelghany, Raed S. Ismail, Sean C. Little, Danlei Zhou, Le Thi Thanh Thuy, Norifumi Kawada, and Jay L. Zweier.
- Journal Title
  
  Nature Communications.
  
  Volume: 8 Issue: 1 Pages: 14807-14807
- DOI
  10.1038/ncomms14807
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Journal Article] Possible Involvement of Nitric Oxide in Enhanced Liver Injury and Fibrogenesis during Cholestasis in Cytoglobin-deficient Mice.2017
- Author(s)
  Van Thuy TT
- Journal Title
  
  Scientific Reports
  
  Volume: - Issue: 1 Pages: 3-7
- DOI
  10.1038/srep41888
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-16K19363
[Journal Article] The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling2017
- Author(s)
  3.Jourd'heuil FL, Xu H, Reilly T, McKellar K, El Alaoui C, Steppich J, Liu YF, Zhao W, Ginnan R, Conti D, Lopez-Soler R, Asif A, Keller RK, Schwarz JJ, Thanh Thuy LT, Kawada N, Long X, Singer HA, Jourd'heuil D.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 37(10) Issue: 10 Pages: 1944-1955
- DOI
  10.1161/atvbaha.117.309410
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Journal Article] Absence of cytoglobin promotes multiple organ abnormalities in aged mice.2016
- Author(s)
  Thuy le TT
- Journal Title
  
  Scientific Reports
  
  Volume: - Issue: 1 Pages: 5-6
- DOI
  10.1038/srep24990
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-26860522, KAKENHI-PROJECT-16K19363
[Journal Article] Discovery of cytoglobin and its roles in physiology and pathology of hepatic stellate cells.2016
- Author(s)
  Yoshizato K,Thuy le TT, Shiota G,Kawada N.
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci.
  
  Volume: 92 Issue: 3 Pages: 77-97
- DOI
  10.2183/pjab.92.77
- NAID
  130005131584
- Data Source
  KAKENHI-PROJECT-25860554, KAKENHI-PROJECT-16H05290
[Journal Article] Pathophysiological role of cytoglobin,the fourth globin in mammals,in liver diseases.2016
- Author(s)
  Thuy le TT,Hai NT,Hai H,Kawada N.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 31 Pages: 257-267
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Pathophysiological role of cytoglobin, the fourth globin in mammals, in liver diseases.2016
- Author(s)
  Thuy Le TT, Nguyen Hai TT, Hai H, Kawada N.
- Journal Title
  
  Histol Histopathol
  
  Volume: 31(3) Pages: 257-267
- Data Source
  KAKENHI-PROJECT-16K19363
[Journal Article] Pathophysiological role of cytoglobin, the fourth globin in mammals, in liver diseases.2016
- Author(s)
  Thuy Le TT, Hai NT, Hai H, Kawada N.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 31 Pages: 257-267
- Data Source
  KAKENHI-PROJECT-25293177
[Journal Article] Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism2015
- Author(s)
  Yuga Teranishi, Tsutomu Matsubara, Kristopher W Krausz, Thi T T Le, Frank J Gonzalez, Katsutoshi Yoshizato,Kazuo Ikeda and Norifumi Kawada
- Journal Title
  
  Laboratory Investigation
  
  Volume: 00 Pages: 1-10
- Data Source
  KAKENHI-PROJECT-25293177
[Journal Article] Cytoglobin expressed in hepatoc stellate cells affects an acute hepatocyte damage via alteration of CYP2E1-mediated xenobiotic metabolism.2015
- Author(s)
  Tｅｒａｎｉｓｈｉ　Y,Matsubara T,Krausz K.W.,Thuy le TT,Gonzalez F. J.,Yoshizato K,Ikeda K,Kawada N.
- Journal Title
  
  Lab Lab Invest.
  
  Volume: 95 Pages: 515-524
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Cytoglobin Deficiency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathway.2015
- Author(s)
  Thuy le TT, Matsumoto Y, Thuy TT, Hai H, Suoh M, Urahara Y, Motoyama H, Fujii H, Tamori A, Kubo S, Takemura S, Morita T, Yoshizato K, Kawada N
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 185 Issue: 4 Pages: 1045-1060
- DOI
  10.1016/j.ajpath.2014.12.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10194, KAKENHI-PROJECT-25293177
[Journal Article] Cytoglobin Deficiency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathway.2015
- Author(s)
  Thuy le TT,Matsumoto Y,Thuy Tuong TV, Hai H,Suoh M,Urahara Y,Motoyama H,Fujii H,Tamori A,Kubo S,Takemura S,Morita T,Yoshizato K, and Kawada N.
- Journal Title
  
  Am J Pathol.
  
  Volume: 185 Pages: 1045-1060
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism.2015
- Author(s)
  Teranishi Y, Matsubara T, Krausz KW, Le TT, Gonzalez FJ, Yoshizato K, Ikeda K, Kawada N.
- Journal Title
  
  Lab Invest.
  
  Volume: 00 Pages: 1-10
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Cytoglobin Deficiency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathway2015
- Author(s)
  Thuy le TT, Matsumoto Y, Thuy TT, Hai H, Suoh M, Urahara Y, Motoyama H, Fujii H, Tamori A, Kubo S, Takemura S, Morita T, Yoshizato K, Kawada N.
- Journal Title
  
  Am J Pathol.
  
  Volume: 185 Pages: 1045-1060
- Data Source
  KAKENHI-PROJECT-25293177
[Journal Article] (1)Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver.2014
- Author(s)
  Motoyama H, Komiya T, Thuy le TT, Tamori A, Enomoto M, Morikawa H, Iwai S, Uchida-Kobayashi S, Fujii H, Hagihara A, Kawamura E, Murakami Y, Yoshizato K, Kawada N.
- Journal Title
  
  Lab Invest.
  
  Volume: 94 Pages: 192-207
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Relationship between inosine triphosphate genotype and outcome of extended therapy in hepatitis C virus patients with a late viral response to pegylated-interferon and ribavirin2014
- Author(s)
  Hoang Hai, Akihiro Tamori, Masaru Enomoto, Hiroyasu Morikawa, Sawako Uchida-Kobayashi, Hideki Fujii, Atsushi Hagihara, Etsushi Kawamura, Le Thi Thanh Thuy, Yasuhito Tanaka and Norifumi Kawada
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 29 Issue: 1 Pages: 201-207
- DOI
  10.1111/jgh.12376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver2014
- Author(s)
  Hiroyuki Motoyama, Tohru Komiya, Le Thi Thanh Thuy, Akihiro Tamori, Masaru Enomoto, Hiroyasu Morikawa, Shuji Iwai, Sawako Uchida-Kobayashi, Hideki Fujii, Atsushi Hagihara, Etsushi Kawamura, Yoshiki Murakami, Katsutoshi Yoshizato, and Norifumi Kawada
- Journal Title
  
  Laboratory Investigation
  
  Volume: 94 Issue: 2 Pages: 194-207
- DOI
  10.1038/labinvest.2013.135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] A pregnant woman with acute hepatitis B in whom vertical transmission was prevented by tenofovir disoproxil fumarate2014
- Author(s)
  Madoka Tooyama , Akihiro Tamori , Akemi Nakano, Hoang Hai , Le Thi Thanh Thuy, Masaru Enomoto , Norifumi Kawada
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 6 Issue: 2 Pages: 173-176
- DOI
  10.1007/s12328-013-0370-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver.2014
- Author(s)
  Motoyama H, Komiya T, Thuy le TT, Tamori A, Enomoto M, Morikawa H, Iwai S,Uchida-Kobayashi S, Fujii H, Hagihara A, Kawamura E, Murakami Y, Yoshizato K,Kawada N.
- Journal Title
  
  Lab Invest.
  
  Volume: 94 Pages: 192-207
- Data Source
  KAKENHI-PROJECT-25293177
[Journal Article] Relationship between inosine triphosphate genotype and outcome of extended therapy in hepatitis C virus patients with a late viral response to pegylated-interferon and ribavirin.2014
- Author(s)
  Hai H, Tamori A, Enomoto M, Morikawa H, Uchida-Kobayashi S, Fujii H, Hagihara A, Kawamura E, Thuy le TT, Tanaka Y, Kawada N.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 29 Pages: 201-207
- Data Source
  KAKENHI-PROJECT-25860554
[Journal Article] Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice2011
- Author(s)
  Thuy le TT, et al
- Journal Title
  
  American J Pathology
  
  Volume: 179 Issue: 2 Pages: 1050-1060
- DOI
  10.1016/j.ajpath.2011.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390232, KAKENHI-PROJECT-22650224, KAKENHI-PUBLICLY-23112518
[Journal Article] Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development2010
- Author(s)
  Spector I, Honig H, Kawada N, Nagler A, Genin O, Pines M.
- Journal Title
  
  Pancreas
  
  Volume: 39 Pages: 1008-15
- Data Source
  KAKENHI-PROJECT-22650224
[Patent] 肝星細胞の活性化並びに肝炎・肝線維化を抑制するサイトグロビン関連ペプチド2019
- Inventor(s)
  河田　則文, LE THI THANH THUY
- Industrial Property Rights Holder
  河田　則文, LE THI THANH THUY
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K08428
[Patent] 肝星細胞の活性化並びに肝炎;肝線維化を抑制するサイトグロビン関連ペプチド2019
- Inventor(s)
  河田　則文, LE THI THANH THUY
- Industrial Property Rights Holder
  河田　則文, LE THI THANH THUY
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Soluble PD-1 and BTLA proteins as biomarkers for predicting the anti-HBV treatment responsiveness.2024
- Author(s)
  Hoang Hai, Masaru Enomoto, Le Thi Thanh Thuy, Naoshi Odagiri, Kohei Kotani, Hiroyuki Motoyama, Ritsuzo Kozuka, Atsushi Hagihara, Etsushi Kawamura, Hideki Fujii, Sawako Uchida-Kobayashi, and Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Cell-cell interaction of LSECs-HSCs in the microenvironment of Diethyl nitrosamine treated Cytoglobin Knock-out mice.2024
- Author(s)
  Nguyen Thi Ha, Le Thi Thanh Thuy, Hoang Hai, Pham Minh Duc, Ngo Vinh Hanh, Nguyen Van Khanh, Nguyen Tran Quang Sang, Inoue Mana, Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression.2024
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha, Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Soluble PD-1 and BTLA proteins as biomarkers for predicting the anti-HBV treatment responsiveness2023
- Author(s)
  Hoang Hai, Masaru Enomoto, Le Thi Thanh Thuy, Naoshi Odagiri, Kohei Kotani, Hiroyuki Motoyama, Ritsuzo Kozuka, Atsushi Hagihara, Etsushi Kawamura, Hideki Fujii, Sawako Uchida-Kobayashi, and Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08083
[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression2023
- Author(s)
  Nguyen Thi Ha, Le Thi Thanh Thuy, Hoang Hai, Pham Minh Duc, Ngo Vinh Hanh, Nguyen Van Khanh, Nguyen Tran Quang Sang, Inoue Mana, Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08083
[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression2023
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha, Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08083
[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression2023
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha and Norifumi Kawada
- Organizer
  37th Annual Meetings for Hepatic Sinusoidal Research Japan
- Data Source
  KAKENHI-PROJECT-22K08083
[Presentation] Interaction between HSC and LSEC populations in the premalignant environment of DEN-treated Cytoglobin knock-out mice.2023
- Author(s)
  Nguyen Thi Ha, Le Thi Thanh Thuy, Pham Minh Duc, Ngo Vinh Hanh, Nguyen Van Khanh, Nguyen Tran Quang Sang, Inoue Mana, Kawada N
- Organizer
  The APASL Oncology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] CD40 expression in liver cancer cells is upregulated by CD4+T cells through IFN gamma and ERK 1/2 pathway.2023
- Author(s)
  Ngo Vinh Hanh, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Kawada N
- Organizer
  European Association for the Study of Liver Annual Congress (EASL) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] The promising therapeutics of recombinant human cytoglobin against acetaminophen-induced liver injury.2023
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha, Vu Ngoc Hieu, Kawada N
- Organizer
  The 3rd Japan Society of Hepatology International Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Baseline sCD27, sCD28, and sCD40 levels - novel predictors of HCC development in HCV-SVR patients2023
- Author(s)
  Le Thi Thanh Thuy, Minh Phuong Dong, Hoang Hai, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  the 32nd Annual Meeting of Asian Pacific Association for the Study of the Liver (APASL)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Role of Cytoglobin in Liver Fibrosis and Steatohepatitis.2023
- Author(s)
  Le Thi Thanh Thuy, Hoang Hai, and Kawada N
- Organizer
  The 3rd Japan Society of Hepatology International Liver Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Global differences in the evaluation and treatment of patients with chronic hepatitis B: a real-B study2023
- Author(s)
  Kudaravalli S, Huang DQ, Kam LY, Nguyen VH, Trinh HN, Hsu YC, Li J, Zhang JQ, Ogawa E, Lee DH, Ito T, Watanabe T, Enomoto M, Preda CM, TanakaY, Yuen MF, Atsukawa M, Marciano S, Buti M, Do S, Wong C, Uojima H, Takahashi H, Quek S XZ, Khine HHTW, Ishigami M, Itokawa N, Go MS, Marin RI, Sandra I, Suzuki T, et al
- Organizer
  74th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07989
[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression.2023
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha and Norifumi Kawada
- Organizer
  第３７回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Interaction between HSC and LSEC populations in the premalignant environment of DEN-treated Cytoglobin knock-out mice2023
- Author(s)
  Nguyen Thi Ha, Le Thi Thanh Thuy, Pham Minh Duc, Ngo Vinh Hanh, Nguyen Van Khanh, Nguyen Tran Quang Sang, Inoue Mana, Kawada N
- Organizer
  APASL STC Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08083
[Presentation] Therapeutic effect of recombinant human Cytoglobin against mouse liver fibrosis and stellate cell activation via ROS scavenger function and activation of JAK-STAT1 pathway.2023
- Author(s)
  Kawada N, Pham Minh Duc, Le Thi Thanh Thuy, and Hoang Hai
- Organizer
  European Association for the Study of Liver Annual Congress (EASL) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Soluble immune checkpoint protein CD27 is a novel prognostic predictor of HCC development in HCV-SVR patients2022
- Author(s)
  Le Thi Thanh Thuy, Minh Phuong Dong, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Cytoglobin, Neuroglobin, Myoglobin, but not Hemoglobin Exhibited Anti-Fibrotic Properties In Vitro and In Vivo2022
- Author(s)
  1.Le Thi Thanh Thuy, Vu Ngoc Hieu, Hoang Hai, Dinh Viet Hoang, and Norifumi Kawada
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K08083
[Presentation] Anti-fibrotic Capacity of Extracellular Globins via Scavenging Reactive Oxygen Species2022
- Author(s)
  Le Thi Thanh Thuy, Vu Ngoc Hieu, Hoang Hai, and Norifumi Kawada
- Organizer
  XXI International Conference on Oxygen Binding and Sensing Proteins (O2BIP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Cytoglobin, Neuroglobin, Myoglobin, but not Hemoglobin Exhibited Anti-Fibrotic Properties In Vitro and In Vivo2022
- Author(s)
  Le Thi Thanh Thuy, Vu Ngoc Hieu, Hoang Hai, Dinh Viet Hoang, and Norifumi Kawada
- Organizer
  the 58th Annual Meeting of the Japan Society of Hepatology
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Interaction between CD4+T cells and tumor cells in hepatocellular carcinoma microenvironment2021
- Author(s)
  Ngo Vinh Hanh, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori, and Norifumi Kawada
- Organizer
  第35回　肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Investigation of CYGB promoter methylation in hepatocellular carcinoma2021
- Author(s)
  Hoang Hai, Le Thi Thanh Thuy, Akihiro Tamori, Shoji Kubo, Shigekazu Takemura, Shogo Tanaka, Atsushi Hagihara, Etsushi Kawamura, Sawako Uchida-Kobayashi, Masaru Enomoto and Norifumi Kawada
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Level of soluble immune checkpoint proteins associate with hepatocellular carcinoma development in patients with chronic hepatitis C2021
- Author(s)
  Dong Minh Phuong, Le Thi Thanh Thuy, Hoang Hai, Akihiro Tamori, Masaru Enomoto, Sawako Uchida-Kobayashi and Norifumi Kawada
- Organizer
  The 57th Annual Meeting of the Japan Society of Hepatology
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Organize Committee, Scientific secretary2021
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  The Asian Pacific Association for the Study of the Liver Single Topic Conference (APASL STC) on “Molecular and Cell Biology of the Liver: Recent Evolution to Clinical Application” in Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Novel Anti-Fibrotic Function of Neuroglobin in vitro and in vivo2021
- Author(s)
  Vu Ngoc Hieu, Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Ninh Quoc Dat, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  Annual Meetings for Hepatic Sinusoidal Research Japan
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Investigation of CYGB promoter methylation as a biomarker for hepatocellular carcinoma2021
- Author(s)
  Hoang Hai, Le Thi Thanh Thuy, Akihiro Tamori, Shoji Kubo, Shigekazu Takemura, Shogo Tanaka, Atsushi Hagihara, Etsushi Kawamura, Sawako Uchida-Kobayashi, Masaru Enomoto and Norifumi Kawada
- Organizer
  American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Cytoglobin inhibits pancreatic cancer growth in vitro and in vivo2021
- Author(s)
  Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Ninh Quoc Dat, Truong Huu Hoang, Dong Minh Phuong, Ngo Vinh Hanh, Yoshihiro Ikura, Kenjiro Kimura, and Norifumi Kawada
- Organizer
  The 107th General Meeting of the Japanese Society of Gastroenterology
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Recombinant human Cytoglobin Deactivates Hepatic Stellate Cells and Prevents Fibrosis Aggravation by Scavenging ROS and Inducing Interferon-Beta2021
- Author(s)
  Vu Ngoc Hieu, Ninh Quoc Dat, Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  第107回　日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Levels of soluble immune checkpoint proteins associate with hepatocellular arcinoma　development in patients with chronic hepatitis C2021
- Author(s)
  Dong Minh Phuong, Le Thi Thanh Thuy, Hoang Hai, Akihiro Tamori, Masaru Enomoto, Sawako Uchida-Kobayashi and Norifumi Kawada
- Organizer
  第57回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Role of CD40 in Hepatocellular Carcinoma2021
- Author(s)
  Ngo Vinh Hanh, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori, and Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver Single Topic Conference (APASL STC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Circulating soluble immune checkpoint proteins as biomarkers for predicting the outcome of antiviral treatment of chronic hepatitis B2021
- Author(s)
  Hoang Hai, Masaru Enomoto, Minh Phuong Dong, Le Thi Thanh Thuy, Atsushi Hagihara, Sawako Uchida-Kobayashi, Akihiro Tamori, and Norifumi Kawada
- Organizer
  29th Japan Gastroenterological Society Week
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Cytoglobin impairs pancreatic cancer growth in vitro and in vivo2021
- Author(s)
  Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Ninh Quoc Dat, Truong Huu Hoang, Dong Minh Phuong, Ngo Vinh Hanh, Yoshihiro Ikura, Kenjiro Kimura, and Norifumi Kawada
- Organizer
  Annual Meeting of the Digestive Disease Week (DDW)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Anti-fibrotic Capacity of Extracellular Globins via Scavenging ROS and Promoting MMP-1 Secretion2021
- Author(s)
  Vu Ngoc Hieu, Le Thi Thanh Thuy, Ninh Quoc Dat, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoshizato and Norifumi Kawada
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Changes of soluble immune checkpoint proteins following antiviral treatment in chronic hepatitis C patients and the roles of the CD27-CD70 pathway in hepatocellular carcinoma development2021
- Author(s)
  Minh Phuong Dong, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference 2021 Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Levels of soluble immune checkpoint proteins following antiviral treatment in chronic hepatitis C patients and the roles of sCD27 in hepatocellular carcinoma development2021
- Author(s)
  Minh Phuong Dong, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Levels of soluble immune checkpoint proteins following antiviral treatment in chronic hepatitis C patients and the roles of sCD27 in hepatocellular carcinoma development2021
- Author(s)
  Minh Phuong Dong, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cells2021
- Author(s)
  Truong Huu Hoang, Misako Sato-Matsubara, Yuasa Hideto, Tsutomu Matsubara, Hayato Urushima, Le Thi Thanh Thuy, Atsuko Daikoku, Yoshinori Okina, Akihiro Tamori, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cells2021
- Author(s)
  ruong Huu Hoang, Misako Sato-Matsubara, Yuasa Hideto, Tsutomu Matsubara, Hayato Urushima, Le Thi Thanh Thuy, Atsuko Daikoku, Yoshinori Okina, Akihiro Tamori, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  第107回　日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Circulating soluble immune checkpoint proteins as biomarkers for predicting the outcome of antiviral treatment of chronic hepatitis B2021
- Author(s)
  Hoang Hai, Masaru Enomoto, Minh Phuong Dong, Le Thi Thanh Thuy, Atsushi Hagihara, Sawako Uchida-Kobayashi, Akihiro Tamori, and Norifumi Kawada
- Organizer
  JDDW　2021　KOBE
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Cytoglobin impairs pancreatic cancer growth in vitro and in vivo.2021
- Author(s)
  Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Ninh Quoc Dat, Truong Huu Hoang, Dong Minh Phuong, Ngo Vinh Hanh, Yoshihiro Ikura, Kenjiro Kimura, and Norifumi Kawada
- Organizer
  Virtual Annual Meeting of the Digestive Disease Week (DDW)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Changes of soluble immune checkpoint proteins following antiviral treatment in chronic hepatitis C patients and the roles of the CD27-CD70 pathway in hepatocellular carcinoma development2021
- Author(s)
  Minh Phuong Dong, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver Single Topic Conference (APASL STC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Recombinant human Cytoglobin Deactivates Hepatic Stellate Cells and Prevents Fibrosis Aggravation by Scavenging ROS and Inducing Interferon-Beta2021
- Author(s)
  Vu Ngoc Hieu, Ninh Quoc Dat, Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  The 107th General Meeting of the Japanese Society of Gastroenterology
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Cytoglobin inhibits pancreatic cancer growth in vitro and in vivo2021
- Author(s)
  Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Ninh Quoc Dat, Truong Huu Hoang, Dong Minh Phuong, Ngo Vinh Hanh, Yoshihiro Ikura, Kenjiro Kimura, and Norifumi Kawada
- Organizer
  第107回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Interaction between CD4+T cells and tumor cells in hepatocellular carcinoma microenvironment2021
- Author(s)
  Ngo Vinh Hanh, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori, and Norifumi Kawada
- Organizer
  Annual Meetings for Hepatic Sinusoidal Research Japan
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Intracellular gaps formation of liver sinusoidal endothelial cells facilitates cancer cell engraftment in liver2021
- Author(s)
  Truong Huu Hoang, Misako Sato-Matsubara, Yuasa Hideto, Tsutomu Matsubara, Hayato Urushima, Le Thi Thanh Thuy, Atsuko Daikoku, Yoshinori Okina, Akihiro Tamori, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference 2021 Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cell2021
- Author(s)
  Truong Huu Hoang, Misako Sato-Matsubara, Yuasa Hideto, Tsutomu Matsubara, Hayato Urushima, Le Thi Thanh Thuy, Atsuko Daikoku, Yoshinori Okina, Akihiro Tamori, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Anti-fibrosis application of overexpression and recombinant human CYGB in multiple models of advanced fibrosis2021
- Author(s)
  Le Thi Thanh Thuy, Ninh Quoc Dat, Vu Ngoc Hieu, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  29th Japan Gastroenterological Society Week
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Anti-fibrotic Capacity of Extracellular Globins via Scavenging ROS and Promoting MMP-1 Secretion2021
- Author(s)
  Vu Ngoc Hieu, Le Thi Thanh Thuy, Ninh Quoc Dat, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoshizato and Norifumi Kawada
- Organizer
  American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Anti-fibrosis application of overexpression and recombinant human CYGB in multiple models of advanced fibrosis2021
- Author(s)
  Le Thi Thanh Thuy, Ninh Quoc Dat, Vu Ngoc Hieu, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  JDDW　2021　KOBE
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Novel Anti-Fibrotic Function of Neuroglobin in vitro and in vivo2021
- Author(s)
  Vu Ngoc Hieu, Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Ninh Quoc Dat, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  第35回　肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Intracellular gaps formation of liver sinusoidal endothelial cells facilitates cancer cell engraftment in liver2021
- Author(s)
  Truong Huu Hoang, Misako Sato-Matsubara, Yuasa Hideto, Tsutomu Matsubara, Hayato Urushima, Le Thi Thanh Thuy, Atsuko Daikoku, Yoshinori Okina, Akihiro Tamori, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  第53回　日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Capacity of Extracellular Globins in suppression of Collagen Production from activated Hepatic Stellate cells via Scavenging ROS and Promoting MMP-1 Secretion2021
- Author(s)
  Vu Ngoc Hieu, Le Thi Thanh Thuy, Ninh Quoc Dat, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoshizato and Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver Single Topic Conference (APASL STC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Capacity of Extracellular Globins in suppression of Collagen Production from activated Hepatic Stellate cells via Scavenging ROS and Promoting MMP-1 Secretion.2021
- Author(s)
  Vu Ngoc Hieu, Le Thi Thanh Thuy, Ninh Quoc Dat, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoshizato and Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference 2021 Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Role of CD40 in Hepatocellular Carcinoma2021
- Author(s)
  Ngo Vinh Hanh, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori, and Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference 2021 Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Hepatocellular carcinoma incidence with tenofovir vs entecavir in chronic hepatitis b: a systematic review and meta-analysis2020
- Author(s)
  Tseng, CH; Hsu, YC; Chen, TH; Ji, FP; Chen, IS; Tsai, YN; Hai, H; Le Thuy, TT; Hosaka, T; Sezaki, H; Borghi, JA; Cheung, R; Enomoto, M; Nguyen, MH.
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Early change in the plasma levels of circulating soluble immune checkpoint proteins in patients with unresectable hepatocellular carcinoma treated by lenvatinib or transcatheter arterial chemoembolization.2020
- Author(s)
  Odagiri N, Enomoto M, Hai H, Le Thuy TT, Dong MP, Suoh M, Kotani K, Hagihara A, Uchida S, Tamori A, Kawada N.
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Recombinant human Cytoglobin scavenging ROS and inducing Interferon-Beta mediated hepatic stellate cells activation and liver fibrosis.2020
- Author(s)
  Vu Ngoc Hieu, Ninh Quoc Dat, Le Thi Thanh Thuy, Hoang Hai,Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  第34回　肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Cytoglobin inhibits pancreatic cancer growth in vitro and in vivo2020
- Author(s)
  2.Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Ninh Quoc Dat, Truong Huu Hoang, Dong Minh Phuong, Ngo Vinh Hanh, Yoshihiro Ikura, Kenjiro Kimura, and Norifumi Kawada
- Organizer
  107th General Meeting of the Japanese Society of Gastroenterology
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Recombinant human Cytoglobin scavenging ROS and inducing Interferon-Beta mediated hepatic stellate cells activation and liver fibrosis2020
- Author(s)
  Vu Ngoc Hieu, Ninh Quoc Dat, Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  56th Annual Meeting of Japanese Society of Hepatology
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Recombinant human Cytoglobin Deactivates Hepatic Stellate Cells and Prevents Fibrosis Aggravation by Scavenging ROS and Inducing Interferon-Beta2020
- Author(s)
  1.Vu Ngoc Hieu, Ninh Quoc Dat, Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada.
- Organizer
  Symposium oral presentation at the 107th General Meeting of the Japanese Society of Gastroenterology
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Chairman for the session of Biology and Medicine2019
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  Vietnam-Japan Science and Technology Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Loss of Cytoglobin linked to specific gut microbiota patterns drives intrahepatic bile duct hyperplasia and reduces survival rate in mice feeding CDAA diet and deoxycholic acid.2019
- Author(s)
  Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Vu Ngoc Hieu, Katsutoshi Yoishizato, and Norifumi Kawada.
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Cytoglobin protects mice from hepatic fibrosis and cancer induced by different aetiologies via scavenging reactive oxygen species2019
- Author(s)
  Le Thi Thanh Thuy, Hoang Hai, Dinh Viet Hoang, Vu Ngoc Hieu, Ninh Quoc Dat, Katsutoshi Yoishizato, and Norifumi Kawada.
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Cytoglobin suppresses liver fibrosis and cancer in mice by regulating oxidative stress2019
- Author(s)
  Le Thi Thanh Thuy, Ninh Quoc Dat, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato, and Norifumi Kawada
- Organizer
  55th Annual Meeting of Japanese Society of Hepatology
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] TGF-β1 transcriptionally repressed cytoglobin expression and enhanced H2O2-induced oxidative DNA damage in activated HSCs.2019
- Author(s)
  Misako Sato-Matsubara, Yoshinori Okina, Tsutomu Matsubara, Atsuko Daikoku1, Krista Rombouts, Le Thi Thanh Thuy, Hideki Fujii1, Kazuo Ikeda, Katsutoshi Yoshizato, Massimo Pinzani, and Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Recombinant Human Cytoglobin Protects Mice from Chemical Induced Liver Fibrosis2019
- Author(s)
  Ninh Quoc Dat, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] The way to the science of a Vietnamese doctor2019
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  the 43rd Meeting of Western Branch of The Japan Society of Hepatology
- Invited
- Data Source
  KAKENHI-PROJECT-19K08428
[Presentation] Cytoglobin suppresses liver fibrosis and cancer in mice by regulating oxidative stress2019
- Author(s)
  Le Thi Thanh Thuy, Ninh Quoc Dat, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Cytoglobin suppresses liver fibrosis and cancer in mice by regulating oxidative stress2019
- Author(s)
  Thi Le,河田則文
- Organizer
  第55回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Role of cytoglibin, the fourth globin in mammals, in liver diseases.2019
- Author(s)
  Le Thi Thanh Thuy, Hoang Hai, and Norifumi Kawada
- Organizer
  VJST2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Profiling of Circulating Immune Checkpoint Proteins in Advanced HCC Patients2019
- Author(s)
  Minh Phuong Dong, Masaru Enomoto, Thi Thanh Thuy Le, Hai Hoang, Atsushi Hagihara, Sawako Uchida-Kobayashi, Akihiro Tamori, Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Establishment of Orthotopic Hepatocellular Carcinoma on the Background of Fibrosis by Intrahepatic and Intrasplenic Tumor Inoculation in Mice.2019
- Author(s)
  Hoang Huu Truong1, Misako Sato-Matsubar, Thuy Thi Thanh Le, Tsutomu Matsubara, Hai Hoang, Atsuko Daikoku, Yoshinori Okina, Hoang Viet Dinh, Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03641
[Presentation] Cytoglobin suppresses liver injury and fibrosis in bile duct ligated mice by regulating nitrosative and oxidative stress2018
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  66th Annual Meeting of AASLD, San Francisco, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Selective overexpression of Cytoglobin in stellate cells attenuates thioacetamide-induced liver injury and fibrosis in mice2018
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  32th Annual Meetings for Hepatic Sinusoidal Research Japan, 2018, December 1st-2nd, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Protective role of hepatic stellate cell-specific overexpression of cytoglobin against liver fibrosis in in vitro and in vivo2018
- Author(s)
  Nguyen Thi Thanh Hai, Le Thi Thanh Thuy, 河田則文
- Organizer
  第54回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H05290
[Presentation] Cytoglobin in Liver Injury and Fibrosis2018
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  Research Seminar in Division of Gastroenterology and Hepatology and Liver Transplant Program at Stanford University Medical Center
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Overexpression of Cytoglobin in stellate cells attenuates liver fibrosis and cholestasis in mice2018
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  American Association for the Study of Liver Diseases (AASLD) Single Topic Conference in Liver Fibrosis, Texas, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Molecular and Cellular Biology of the Liver in Health and Disease2018
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  the Asian Pacific Association for the Study of the Liver Single Topic Conference (APASL STC)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Role of Cytoglobin in the Development of Liver Fibrosis and Cancer in Human and in a Mouse Model of Non-Alcoholic Steatohepatitis2017
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  the Asian Pacific Association for the Study of the Liver Single Topic Conference (APASL STC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] グロビンファミリーの第4のタンパク質であるcytoglobinは胆汁鬱滞誘発性肝障害に対して一酸化窒素調節を介して保護作用を発揮する(Cytoglobin, the fourth member of globin family, protects cholestasis induced liver injury throughout regulation of Nitric oxide)(英語)2017
- Author(s)
  Le Thi Thanh Thuy, 河田則文
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H05290
[Presentation] Regulation of liver carcinogenesis by high fat diet,bile acid,and antibiotics in Cygb knockout mice2017
- Author(s)
  Le Thi Thanh Thuy、Toung Thi Van Thuy、Hoang Hai、吉里勝利、河田則文
- Organizer
  第31回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-16H05290
[Presentation] Cytoglobin, the fourth member of globin family, protects cholestasis induced liver injury throughout regulation of Nitric oxide2017
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  53th Annual Meeting of Japanese Society of Hepatology
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Absence of Cytoglobin, a Novel Marker of Hepatic Stellate Cells, Promotes Multiple Organ Abnormality in Aged Mice via Nitric Oxide Induced Senescence2017
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  19th International Symposium on Cells of the Hepatic Sinusoid
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Spontaneously and Chemical/Diet Induced Liver Fibrosis and Cancer Development in Cygb-deficient Mice via Regulating Nitric Oxide2016
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  XIXth International conference on "Oxygen binding and sensing proteins
- Place of Presentation
  ハンブルグ（ドイツ）
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Correlation of Cytoglobin Level in Stellate Cells with Promotion or Attenuation of Liver Fibrosis and Cancer in Mice2016
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  AASLD The Liver Meeting
- Place of Presentation
  ボストン（アメリカ）
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Protective Role of Cytoglobin in Liver Inflammation and Fibrogenesis in Mouse Steatohepatitis Model.2016
- Author(s)
  Thuy le TT
- Organizer
  APASL2016
- Place of Presentation
  グランドプリンスホテル新高輪(東京都･港区)
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Loss of Cytogｌobin, a stellate cell-specific globin, induced spontaneously and diet derived liver fibrosis and cancer development2016
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16H05290
[Presentation] Cytoglobin Protects Mice from Non-Alcoholic Stetatohepatitis-induced Liver Fibrosis and Cancer via Regulation of Oxidative Stress Pathway2016
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  第30回肝類洞壁細胞研究会
- Place of Presentation
  富山国際会議場
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16H05290
[Presentation] Cytoglobin Protects Mice from Non-Alcoholic Stetatohepatitis-induced Liver Fibrosis and Cancer via Regulation of Oxidative Stress Pathway2016
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  第30回肝類洞壁細胞研究会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Role of Cytoglobin, the Fourth Globin in Mammals, in Liver Diseases2016
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  Vietnamese-Japanese Student Scientific Exchange Meeting
- Place of Presentation
  九州大学（福岡県福岡市）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K19363
[Presentation] Loss of Cygb accelerates liver fibrosis and cancer development despite of its etiology.2015
- Author(s)
  Thuy le TT
- Organizer
  ISHSR
- Place of Presentation
  アシロマ(アメリカ合衆国)
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Cytoglobin Deficiency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathaway.2015
- Author(s)
  Thuy le TT
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本(熊本県・熊本市)
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Loss of Cytoglobin Exacerbates Liver Fibrosis and Cancer Development in Steatohepatitis through the activation of Oxidative Stress Pathaway.2015
- Author(s)
  ＴHuy le TT
- Organizer
  AASLD
- Place of Presentation
  サンフランシスコ(アメリカ合衆国)
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Absence of Cytoglobin, a Specific Marker of Hepatic Stellate Cells,Promotes Multiple Organ Abnormality in Aged Mice via Increased Nitric Oxide.2015
- Author(s)
  Ｔhuy le TT
- Organizer
  第29回肝類洞壁細胞研究会学術集会
- Place of Presentation
  秋田市にぎわい交流館ＡＵ(秋田県・秋田市)
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Loss of Cytoglobin Exacerbates Liver Fibrosis and Cancer Development in Steatohepatitis by Activating the Oxidative Stress Pathway2015
- Author(s)
  Le, Thuy T、Matsumoto, Yoshinari、Tuong Thi Van Thuy、Hoang Hai、Yoshizato, Katsutoshi、Kawada, Norifumi
- Organizer
  American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco(U S A)
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293177
[Presentation] Deficiency of Cytoglobin promoted hepatosteatosis to liver cancer throughout activating oxidative stress pathway2013
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  Asian Pacific Association of Liver Diseases meeting
- Place of Presentation
  Singapore, Suntec Singapore Convention & Exhibition Centre
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Promotion of liver tumor development in NASH model of Cytoglobin-deficient mice2013
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  17th ISHSR meeting
- Place of Presentation
  Osaka, Osaka International Convention Center
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Acceleration of liver cancer development in both chemical/diet administrated Cytoglobin-deficient mice via priming of stallate cells and the activation of local fibrosis, inflammation , and oxidative stress2013
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  American Association for Study of Liver Diseases Meeting
- Place of Presentation
  Washington DC, USA, Washington DC Convention Center
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Promotion of liver tumor development in NASH model of Cytoglobin-deficient mice2013
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  49th JSH meeting
- Place of Presentation
  Tokyo, 京王プラザホテル
- Data Source
  KAKENHI-PROJECT-25860554
[Presentation] Promotion of liver and lung tumorgenesis in DEN-treated cytoglobin-deficient mice2011
- Author(s)
  Le Thi Than Thuy
- Organizer
  ISHSR
- Place of Presentation
  Florence, Italy
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22650224
[Presentation] Cytoglobin Deficiency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathway
- Author(s)
  Le Thi Thanh Thuy
- Organizer
  第28回肝類洞壁細胞研究会学術集会
- Place of Presentation
  アークホテル岡山(岡山県・岡山市)
- Year and Date
  2014-12-13 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25860554
[]

1. KAWADA Norifumi (30271191)

# of Collaborated Projects: 7 results

# of Collaborated Products: 56 results
2. 松原三佐子 (00635120)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MOTOYAMA Hiroyuki (00573601)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Enomoto Masaru (20423874)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. Tamori Akihiro (30291595)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. Uchida-Kobayashi Sawako (60382074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 小谷晃平 (50711793)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HOANG HAI (60623246)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
9. OGAWA Tomohiro (70448752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Fujii Hideki (20382070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松原勤 (20628698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. KUBO Shoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 及川大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 池田一雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 宇留島隼人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 竹村茂一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 小塚立蔵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 萩原淳司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 松原三佐子(佐藤三佐子)

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results

LE THITHANHTHUY ＬＥ ＴＨＩＴＨＡＮＨＴＨＵＹ

Le Thi Thanh Thuy LE THITHANHTHUY

LE THUY LE THUY

Le Thuy レイ トゥイ

LE Thuy

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Novel anti-fibrotic properties of heme binding proteins including Neuroglobin, Myoglobin, and Hemoglobin in comparison with Cytoglobin in vitro and in vivoPrincipal Investigator

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Cytoglobin overexpression inhibits liver fibrosis and cancer development via anti-oxidant functionPrincipal Investigator

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Protective role of CYGB in prevention of liver fibrosis development in vitro and in vivoPrincipal Investigator

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Loss of Cytoglobin Exacerbates Liver Fibrosis and Cancer Development in Steatohepatitis by Activating the Oxidative Stress PathawayPrincipal Investigator

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LE THITHANHTHUY ＬＥＴＨＩＴＨＡＮＨＴＨＵＹ

Le Thuy レイトゥイ