NAKANISHI Yumiko 中西裕美子

Researcher Number	10614274
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人理化学研究所, 生命医科学研究センター, 客員研究員 2021 – 2023: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2019 – 2020: 地方独立行政法人神奈川県立産業技術総合研究所, 「腸内細菌叢」プロジェクト, 研究員(任期有) 2018 – 2020: 国立研究開発法人理化学研究所, 生命医科学研究センター, 客員研究員 2017: 理化学研究所, 生命医科学研究センター, 研究員 2016 – 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 研究員 2012 – 2014: 慶應義塾大学, 政策・メディア研究科, 研究員
Review Section/Research Field	Principal Investigator Food science / Basic Section 38050:Food sciences-related Except Principal Investigator Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 38050:Food sciences-related / Basic Section 55010:General surgery and pediatric surgery-related / Immunology / Applied microbiology
Keywords	Principal Investigator 腸内細菌 / プレバイオティクス / メタボローム / 性別 / 動脈硬化 / 性差 / 代謝物 / 肥満 / 加齢 / 腸内フローラ … More Except Principal Investigator … More 腸内細菌 / 自己免疫疾患 / 腸内細菌叢 / 統合オミクス解析 / 1型糖尿病 / 多発性硬化症 / GPR41 / メタボローム / 免疫 / 疾患予防 / 腸管バリア / トランス脂肪酸 / 2型糖尿病 / プロピオン酸 / 喘息 / エンドリシン / 小児アレルギー / 糖尿病 / アレルギー / 宿主ー腸内細菌叢相互作用 / 回腸嚢炎 / 潰瘍性大腸炎 / 統合オミクス手法 / 大腸炎 / IgA / Th17型Ｔ細胞 / 自己抗原交叉ペプチド / CD8陽性制御性Ｔ細胞 / １型糖尿病 / STZ誘導1型糖尿病 / 実験的自己免疫性脳脊髄炎（EAE) / CD8+制御性Ｔ細胞 / ルミノコッカス属菌 / トレハロース / 寄生虫 / EAE（実験的自己免疫性脳脊髄炎） / Treg / 妊娠 / 酪酸 / Aire / 胸腺 / 制御性T細胞 / 短鎖脂肪酸 / 食物繊維 / シロアリ / 原生生物 / 共生 / シングルセル Less

Effects of maternal immune activation on autoimmune diseases in offsprings
- Principal Investigator
  
  宮内栄治
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Gunma University
宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Institute of Physical and Chemical Research
The alteration of gut microbiome during treatment of pouchitis in patients with ulcerative colitis.
- Principal Investigator
  
  Uchino Motoi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
The impact of gut microbiota on autoimmune diseases
- Principal Investigator
  
  Ohno Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Institute of Physical and Chemical Research
Studies on the effects of sex differences in gut bacteria and metabolites on diseasesPrincipal Investigator
- Principal Investigator
  
  Nakanishi Yumiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Institute of Physical and Chemical Research
  Kanagawa Institute of Industrial Sclence and Technology
Unraveling of aging induced obese-type gut microbiota and development of the prevention methodPrincipal Investigator
- Principal Investigator
  
  Nakanishi Yumiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Institute of Physical and Chemical Research
Maternal high fiber diet during pregnancy and lactation influences regulatory T cell differentiation in offspring in mice
- Principal Investigator
  
  NAKAJIMA Akihito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
The development and application of single-cell metabolic analytical techniques for environmental microbes
- Principal Investigator
  
  KIHARA kumiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  Tokyo Institute of Technology
Evaluation of the effects of prebiotics on murine gut microbial ecology by multi-omic based network analysisPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Yumiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Keio University

All 2024 2023 2021 2019 2017 2013 Other

All Journal Article Presentation Book

[Book] 腸内細菌叢 : 健康と疾患を制御するエコシステム2019
- Author(s)
  中西裕美子、大野博司
- Total Pages
  203
- Publisher
  羊土社
- ISBN
  4758103763
- Data Source
  KAKENHI-PROJECT-16K18712
[Journal Article] Gut microbiota and fecal metabolites in sustained unresponsiveness by oral immunotherapy in school-age children with cow's milk allergy2024
- Author(s)
  Shibata Ryohei、Itoh Naoka、Nakanishi Yumiko、Kato Tamotsu、Suda Wataru、Nagao Mizuho、Iwata Tsutomu、Yoshida Hideo、Hattori Masahira、Fujisawa Takao、Shimojo Naoki、Ohno Hiroshi
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 1 Pages: 126-136
- DOI
  10.1016/j.alit.2023.10.001
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00452
[Journal Article] Fatty acid overproduction by gut commensal microbiota exacerbates obesity2023
- Author(s)
  Takeuchi Tadashi、Kameyama Keishi、Miyauchi Eiji、Nakanishi Yumiko、Kanaya Takashi、Fujii Takayoshi、Kato Tamotsu、Sasaki Takaharu、Tachibana Naoko、Negishi Hiroki、Matsui Misato、Ohno Hiroshi
- Journal Title
  
  Cell Metabolism
  
  Volume: 35 Issue: 2 Pages: 361-375.e9
- DOI
  10.1016/j.cmet.2022.12.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-22H00452
[Journal Article] Gut microbial carbohydrate metabolism contributes to insulin resistance2023
- Author(s)
  Takeuchi Tadashi、Kubota Tetsuya、Nakanishi Yumiko、Tsugawa Hiroshi、Suda Wataru、Kwon Andrew Tae-Jun、Yazaki Junshi、Ikeda Kazutaka、Nemoto Shino、Mochizuki Yoshiki、Kitami Toshimori、Yugi Katsuyuki、Mizuno Yoshiko、Yamamichi Nobutake、Yamazaki Tsutomu、Takamoto Iseki、Kubota Naoto、Kadowaki Takashi、
- Journal Title
  
  Nature
  
  Volume: 621 Issue: 7978 Pages: 389-395
- DOI
  10.1038/s41586-023-06466-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21H03178, KAKENHI-PROJECT-22H00452
[Journal Article] The propionate-GPR41 axis in infancy protects from subsequent bronchial asthma onset2023
- Author(s)
  Ito Takashi、Nakanishi Yumiko、Shibata Ryohei、Sato Noriko、Jinnohara Toshi、Suzuki Sayo、Suda Wataru、Hattori Masahira、Kimura Ikuo、Nakano Taiji、Yamaide Fumiya、Shimojo Naoki、Ohno Hiroshi
- Journal Title
  
  Gut Microbes
  
  Volume: 15 Issue: 1
- DOI
  10.1080/19490976.2023.2206507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00452
[Journal Article] Bacterial cancer therapy in autochthonous colorectal cancer affects tumor growth and metabolic landscape2021
- Author(s)
  Mackie Gillian M.、Copland Alastair、Takahashi Masumi、Nakanishi Yumiko、Everard Isabel、Kato Tamotsu、Oda Hirotsugu、Kanaya Takashi、Ohno Hiroshi、Maslowski Kendle M.
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 23
- DOI
  10.1172/jci.insight.139900
- Data Source
  KAKENHI-PROJECT-19H01030
[Journal Article] Acetate differentially regulates IgA reactivity to commensal bacteria2021
- Author(s)
  Takeuchi Tadashi、Miyauchi Eiji、Kanaya Takashi、Kato Tamotsu、Nakanishi Yumiko、Watanabe Takashi、Kitami Toshimori、Taida Takashi、Sasaki Takaharu、Negishi Hiroki、Shimamoto Shu、Matsuyama Akinobu、Kimura Ikuo、Williams Ifor R.、Ohara Osamu、Ohno Hiroshi
- Journal Title
  
  Nature
  
  Volume: 595 Issue: 7868 Pages: 560-564
- DOI
  10.1038/s41586-021-03727-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01030, KAKENHI-PROJECT-21H04862, KAKENHI-PROJECT-19K05907
[Journal Article] Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice2017
- Author(s)
  Nakajima, A. Kaga, N. Nakanishi, Y. Ohno, H. Miyamoto, J. Kimura, I. Hori, S. Sasaki, T. Hiramatsu, K. Okumura, K. Miyake, S. Habu, S. Watanabe, S.
- Journal Title
  
  J Immunol
  
  Volume: 199 Issue: 10 Pages: 3516-3524
- DOI
  10.4049/jimmunol.1700248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05789, KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-17H04218, KAKENHI-PROJECT-15H05344, KAKENHI-PROJECT-15K08533
[Presentation] Aging-related alterations in the intestinal environment lead to gut dysbiosis with a potential to induce obesity in mice2019
- Author(s)
  Yumiko Nakanishi
- Organizer
  International Conference on Ageing 2019 (ICA2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18712
[Presentation] 2型糖尿病や肥満の発症に関わる腸内細菌と代謝物の探索2019
- Author(s)
  中西裕美子、竹内直志、水野由子、山道信毅、須田亙、服部正平、窪田直人、窪田哲也、大野博司
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K05923
[Presentation] Aging-related alteration of the murine intestinal environment induces an obese-type gut dysbiosis2019
- Author(s)
  Yumiko Nakanishi
- Organizer
  URICAS SYMPOSIUM 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18712
[Presentation] 環境微生物の代謝産物をシングルセルで観察できるか～ムカシシロアリの腸内共生原生生物ミクソトリカを例に～2013
- Author(s)
  木原久美子, 中西裕美子, Nathan Lo, 本郷裕一, 福田真嗣, 守屋繁春
- Organizer
  第29回日本微生物生態学会大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25660054
[Presentation] ラフィノース接食マウスの腸内フローラ解析とメタボローム解析2013
- Author(s)
  中西　裕美子
- Organizer
  日本農芸化学会201３年度　仙台大会
- Place of Presentation
  東北大学　川内北キャンパス
- Data Source
  KAKENHI-PROJECT-24780133
[Presentation] Evaluation of the effects of age on murine gut ecosystem by multi-omics analysis2013
- Author(s)
  中西裕美子
- Organizer
  第2回マトリョーシカ型生物学研究会・公開国際シンポジウム
- Place of Presentation
  ホテル京都ガーデンパレス(京都府)
- Data Source
  KAKENHI-PROJECT-24780133
[Presentation] A metabolomic evaluation of the effects of raffinose on murine gut microbial ecology
- Author(s)
  Yumiko Nakanishi, Masayo Mori, Tomoyoshi Soga, Kiharu Igarashi, Masaru Tomita
- Organizer
  Metabolomics2014
- Place of Presentation
  マリカホール（山形県鶴岡市）
- Year and Date
  2014-06-23 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-24780133
[Presentation] 原生生物１細胞のメタボロミクス解析の現状～シロアリ腸内共生原生生物を例に～
- Author(s)
  木原久美子, 中西裕美子, Nathan Lo, 本郷裕一, 福田真嗣, 守屋繁春
- Organizer
  第３回マトリョーシカ型生物学研究会
- Place of Presentation
  神戸大学(兵庫県)
- Year and Date
  2014-07-11 – 2014-07-13
- Data Source
  KAKENHI-PROJECT-25660054

1. 加藤完 (20632946)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. OHNO Hiroshi (50233226)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. 宮内栄治 (60634706)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 下川周子 (60708569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KIHARA kumiko (50622916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. MORIYA Shigeharu (00321828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. FUKUDA Shinji (80435677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. NAKAJIMA Akihito (30439294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OKUMURA Ko (50009700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HABU Sonoko (30051618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MIYAKE Sachiko (50266045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIRAMATSU Keiichi (10173262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WATANABE Sumio (20138225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HORI Shohei (50392113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. Uchino Motoi (00388810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石戸聡 (10273781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 堀尾勇規 (10838999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小椋英樹 (20573174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 孫安生 (30447924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 皆川知洋 (70839000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 池内浩基 (80319863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 桑原隆一 (90839010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 伊藤崇 (20823561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. ITO Ayumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TACHIBANA naoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KUBOTA Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKANISHI Yumiko 中西 裕美子

Research Projects

Research Products

Co-Researchers

Effects of maternal immune activation on autoimmune diseases in offsprings

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The alteration of gut microbiome during treatment of pouchitis in patients with ulcerative colitis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The impact of gut microbiota on autoimmune diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the effects of sex differences in gut bacteria and metabolites on diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Unraveling of aging induced obese-type gut microbiota and development of the prevention methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maternal high fiber diet during pregnancy and lactation influences regulatory T cell differentiation in offspring in mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development and application of single-cell metabolic analytical techniques for environmental microbes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of the effects of prebiotics on murine gut microbial ecology by multi-omic based network analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 腸内細菌叢 : 健康と疾患を制御するエコシステム2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Gut microbiota and fecal metabolites in sustained unresponsiveness by oral immunotherapy in school-age children with cow&apos;s milk allergy2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Fatty acid overproduction by gut commensal microbiota exacerbates obesity2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gut microbial carbohydrate metabolism contributes to insulin resistance2023

Author(s)

Journal Title

DOI

NAKANISHI Yumiko 中西裕美子

[Journal Article] Gut microbiota and fecal metabolites in sustained unresponsiveness by oral immunotherapy in school-age children with cow's milk allergy2024