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Watanabe Sumio  渡辺 純夫

ORCIDConnect your ORCID iD *help
… Alternative Names

渡辺 純夫  ワタナベ スミオ

WATANABE Sumio  渡辺 純夫

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Researcher Number 20138225
External Links
Affiliation (Current) 2022: 順天堂大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2020: 順天堂大学, 医学部, 特任教授
2017 – 2018: 順天堂大学, 医学部, 特任教授
2016: 順天堂大学, 医学部, 教授
2011 – 2014: 順天堂大学, 医学部, 教授
2010: 順天堂大学, 医学部, 主任教授 … More
2009: Juntendo University, 医学部, 教授
2006 – 2007: Jyuntendo University, schoolof medicine, Professor, 医学部, 教授
2002 – 2005: 秋田大学, 医学部, 教授
1999: School of Medicine, Akita University, Professor, 医学部, 教授
1995 – 1998: Juntendo Univ.School of Medicine, Assistant Professor, 医学部, 助教授
1991 – 1994: 順天堂大学, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Gastroenterology / Gastroenterology / Experimental pathology / Immunology
Keywords
Principal Investigator
オートファジー / 肝再生 / 脂肪性肝炎 / 酸化ストレス / リソソーム / liver transplantation / bile / microcirculation / Ito cell / Kupffer cell … More / calcium / cytoskeleton / サイトカイン / HSP / PTEN / 核マトリクス蛋白 / 肝障害 / 細胞死 / 炎症 / エイコサペンタエン酸 / インスリン抵抗性 / ミトコンドリア / 潰瘍性大腸炎 / 脂肪性肝疾患 / カテプシン / 慢性肝炎 / endothelin / 肝移植 / 胆汁 / 微小循環 / 伊東細胞 / クッパー細胞 / カルシウム / 細胞骨格 / エンドセリン / 毛細胆管 / 胆汁分泌 / eudothelin / 胃潰瘍 / 増殖因子 / 細胞遊走 / 細胞分化 / ヘリコバクター・ピロリ / ストレス / 損傷修復 / 細胞分裂 / ヘリコバクターピロリ / 胃粘膜損傷 / 消化性潰瘍 / 細胞培養 / 線維芽細胞 / 血管内皮細胞 / インスリン様増殖因子 / 細胞外基質 / gastric ulcer / growth factor / cytokine / migration / differentiation / Helicobacter pylori / stress / アデノシン / 炎症性サイトカイン / サイクリックAMP / Adenosine / inflammatory cytokine / 肝発癌 / 抗酸化剤 / N-アセチルシステイン / steatohepatitis / oxidative stress / hepatic caricinogenesis / antioxidant / N-acetyleisteine / バイオマーカー / 膵癌 / 肝癌 / 核マトリクス / 膵炎 / アミノ酸代謝 … More
Except Principal Investigator
proliferation / epimorphin / 伊東細胞 / gastric ulcer / migration / wound healing / 炎症 / 微小循環 / 細胞骨格 / 胃潰瘍 / 細胞遊走 / 細胞増殖 / growth factor / cytoskeleton / culture cell / Helicobacter pylori / 損傷修復 / 肝再生 / 分化誘導 / 肝硬変 / liver regeneration / NOD1 / ノックアウトマウス / Peroxiredoxin / PTEN / 発癌 / 酸化ストレス / inflammation / COX-2 / Pten遺伝子 / autophagosome / autolysosome / class I PI3-kinase / Pten gene / NASH / 悪性腫瘍 / 細胞骨格蛋白 / 画像解析 / 内視鏡(近赤外) / 分光分析 / 酸素化 / 医工学 / 近赤外光 / 内視鏡 / cancer / microcirculation / near-infrared light / image analysis / electronic endoscope / spectrophotometry / oxygenation / biomedical engineering / 肝移植 / 臓器保存 / Kupffer細胞 / 組織酸素化 / 再還流障害 / エンドセリン / 酸素飽和度 / レーザー顕微鏡 / 微小循環障害 / 白血球粘着 / グラフト障害 / 臓器反射スペクトル法 / Liver Transplantation / Microcirculation / Preservation of Liver Graft / Cytoskeleton / Kupffer cells / Oxygenation / Ischeima-referfusion Injury / Ito cells / 増殖因子 / 創傷治療 / 培養細胞 / gastric ulcer 男性度 / growth factor 増殖因子 / cytoskeleton 細胞骨性 / migration 細胞遊走 / proliferation 細胞増殖 / wound healing 損傷性対 / culture cell 培養細胞 / 胃粘膜細胞 / 損傷修復モデル / 細胞外基質 / 受容体 / Apotosis / 胆汁酸 / アルコール / ラジカル / Apoptosis / apotosis / bile acid / alcohol / radical / 形態形成 / 分化 / Ito cell / differentiation / organization / 肝類洞壁 / 肝線維化 / Hepatic sinusoid / morphogenesis / liver cirrhosis / 増殖 / アポトーシス / 自然免疫 / Nod1 / Nod 1 / CARD4 / 感染 / apoptosis / innate immune response / knockout mice / 分子シャペロン / 胃粘膜防御機構 / 胃粘膜修復機構 / ストレス / 胃粘膜病変 / 熱ショック蛋白質 / 胃粘膜傷害 / 粘膜防御 / 消化性潰瘍 / 粘膜修復 / 亜鉛 / 胃粘膜障害 / molecular chaperon / gastric mucosal protection / gastric mucosal restoration / stress / gastric mucosal lesion / heat shock protein / Crohn病 / 病因 / カテプシン / peroxiredoxin / Crohn's disease / Etiology / Cathepsin / 非アルコール性脂肪性肝炎 / 遺伝子欠損マウス / リポポリサッカライド / オステオポンチン / Pten / 肝細胞 / クッパー細胞 / 腸内細胞叢 / 肝癌 / 脂質 / シグナル伝達 / nonalcoholic steatohepatitis / gene-mutated mice / carcinogenesis / lipopolysaccharide / osteopontin / oxidative stress / MEK-ERKシグナル / アポトーシス抵抗性 / 薬剤代謝関連遺伝子 / MEK-ERK signaling / anti-apoptosis / オートファジー / Atg複合体 / 線維化 / autophagy / Atg conjugation / 脂肪肝 / 治療薬 / Pten遺伝 / ミトコンドリア / reactive oxygen speies / steatosis / therapeutic agent / 腸内細菌 / 食物繊維 / 短鎖脂肪酸 / 制御性T細胞 / 胸腺 / Aire / GPR41 / 酪酸 / 妊娠 / Treg Less
  • Research Projects

    (22 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (34 People)
  •  The relationship between autophagy-related nuclear matrix protein and epigenetic regulation of amino acid metabolismPrincipal Investigator

    • Principal Investigator
      渡辺 純夫
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Juntendo University
  •  Development of an early diagnosis method targeting nuclear matrix protein for autophagy-related digestive disorder diseasePrincipal Investigator

    • Principal Investigator
      WATANABE SUMIO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Maternal high fiber diet during pregnancy and lactation influences regulatory T cell differentiation in offspring in mice

    • Principal Investigator
      NAKAJIMA Akihito
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University
  •  New therapeutic strategy to non-alcoholic liver disease targeting on autophagyPrincipal Investigator

    • Principal Investigator
      WATANEBE Sumio
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Central role of autophagy in the pathogenesis of gastrointestinal and hepatic diseases.Principal Investigator

    • Principal Investigator
      WATANABE Sumio
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Role of lipid and oxidative stress on carcinogenesis in the digestive systemPrincipal Investigator

    • Principal Investigator
      WATANABE Sumio
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Autophagy is involved in inflammation, fibrosis, and carcinogenesis-A study using mice model

    • Principal Investigator
      HORIE Yasuo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Akita University
  •  The study of NASH mechanism-in terms of reactive oxygen species and mitochondrial function-

    • Principal Investigator
      OHSHIMA Shigetoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Akita University
  •  Analysis of the effect of activated MEK-ERK signaling in the chemoresistance-basal research to the molecular targeting therapy

    • Principal Investigator
      OTAKA Michiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Akita University
  •  The involvement of lipid signaling to the onset and progression of nonalcoholic steatohepatitis and the development of hepatocellular carcinoma

    • Principal Investigator
      HORIE Yasuo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Akita University
  •  Cathepsin as a novel etiological agent or therapeutic target in Crohn's disease

    • Principal Investigator
      IIZUKA Masahiro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Akita University
  •  Analysis of anima models of inflammatory bowel disease and therapeutics application for inflammatory bowel diseasePrincipal Investigator

    • Principal Investigator
      WATANABE Sumio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Akita University
  •  Functional Analysis of NODI Gene Related with Proliferation, Apoptosis, and Innate Immune Response Using Knockout Mice

    • Principal Investigator
      HORIE Yasuo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Akita University
  •  Role of molecular chaperon in gastric mucosal injury and restoration

    • Principal Investigator
      OTAKA Michiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Akita University
  •  Biological modulation of the epithelial-mesenchymal interaction in gut wound repair process.Principal Investigator

    • Principal Investigator
      WATANABE Sumio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      AKITA UNIVERSITY
      Juntendo University
  •  The role of epimorphin, as a morphogen, in human liver disease

    • Principal Investigator
      HIROSE Miyoko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  The analysis of physical stimulation to proliferative gastric cells.

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      JUNTENDO UNIVERSITY SCHOOL OF MEDICINE
  •  A ROLE OF EPIMORPHIN IN LIVER REGENERATION

    • Principal Investigator
      HIROSE Miyoko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine
  •  Molecular and cell biological investigation about the healing mechanism of gastric mucosal damage.

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine
  •  Investigation of the bile formation in the liver : basic analysis for transplantationPrincipal Investigator

    • Principal Investigator
      WATANABE Sumio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine
  •  Developmental Research on Preservation of Liver Graft by Improving the Hepatic Microcirculation

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine
  •  Development of an Endoscopic System for Treating cancerous lesions by Immunological - and medico - technological Modification of Tissue Microcirculation.

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine

All 2019 2017 2015 2014 2013 2011 2010 2009 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Cathepsin L-deficiency enhances liver regeneration after partial hepatectomy2019

    • Author(s)
      Sato Toshifumi、Yamashina Shunhei、Izumi Kosuke、Ueno Takashi、Koike Masato、Ikejima Kenichi、Peters Christoph、Watanabe Sumio
    • Journal Title

      Life Sciences

      Volume: 221 Pages: 293-300

    • DOI

      10.1016/j.lfs.2019.02.040

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-18K08016, KAKENHI-PROJECT-16H05293
  • [Journal Article] Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice.2017

    • Author(s)
      Nakajima, A. Kaga, N. Nakanishi, Y. Ohno, H. Miyamoto, J. Kimura, I. Hori, S. Sasaki, T. Hiramatsu, K. Okumura, K. Miyake, S. Habu, S. Watanabe, S.
    • Journal Title

      The Journal of Immunology

      Volume: 199 Pages: 3516-3524

    • DOI

      10.4049/jimmunol.1700248

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05789, KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-17H04218, KAKENHI-PROJECT-15H05344, KAKENHI-PROJECT-15K08533
  • [Journal Article] Abnormality of autophagic function and cathepsin expression in the liver from patients with non-alcoholic fatty liver disease2014

    • Author(s)
      Yuka Fukuo, Shunhei Yamashina, Hiroshi Sonoue, Atsushi Arakawa, Eisuke Nakadera, Tomonori Aoyama, Akira Uchiyama, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
    • Journal Title

      Hepatol Res.

      Volume: 未定 Pages: 1026-1036

    • DOI

      10.1111/hepr.12282

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590989, KAKENHI-PROJECT-24390191, KAKENHI-PROJECT-24590995, KAKENHI-PROJECT-24590996
  • [Journal Article] Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression2011

    • Author(s)
      Inami Y, Yamashina S, Izumi K, Ueno T, Tanida I, Ikejima K, Watanabe S
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412(4) Pages: 618-618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Journal Article] Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells2011

    • Author(s)
      Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komats M
    • Journal Title

      J Cell Biol

      Volume: 193(2) Pages: 275-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Journal Article] Non-alcoholic steatohepatitis and hepatocellular carcinoma lessons fromhepatocyte-specific phosphatase and tensin homolog(PTEN)-deficient mice2007

    • Author(s)
      Watanabe S, Horie Y, Kataoka E, Sato W, Dohmen T, Ohshima S, Goto T, Suzuki A.
    • Journal Title

      J.Gastroenterol.Hepatol. 22(Suppl1)

    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Non-alcoholic steatohepatitis and hepatocellular carcinoma : lessons from hepatoeyte-specific phosphatase and tensin homolog (PTEN)-defient mice.2007

    • Author(s)
      Watanabe S. Horie Y. Kataoka E. Sato W. Dohmon T. Ohshima S. Goto T. Suzuki A.
    • Journal Title

      J. Gastroenterol. Hepatol 22 (Suppl 1)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Hepatic gene expression in hepatocyte-specific Pten deficient mice showing Steatohepatitis without ethanol challenge.2006

    • Author(s)
      Sato W. Horie Y. Kataoka E. Qhshima S. Dohmen T. Iizuka M. Sasaki J. Sasaki T. Hamada K. Kishimoto H. Suzuki A. Watanabe S.
    • Journal Title

      Hepatol. Res. 34

      Pages: 256-265

    • NAID

      10020405034

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Rotavirus double-stranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells.2006

    • Author(s)
      Sato A, Iizuka M, Nakagomi O, Suzuki M, Horie Y, Konno S, Hirasawa F, Sasaki K, Shindo K, Watanabe S
    • Journal Title

      J Gastroentrol Hepatol 21(3)

      Pages: 521-30

    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Infliximab as a treatment for systemic amyloidosis associeted with Crohn's disease.2006

    • Author(s)
      Iizuka M, Konno S, Horie Y, Itou H, Shindo K, Watanabe S
    • Journal Title

      Gut 55(5)

      Pages: 744-5

    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Sucralfate prevents the delay of wound repair in intestinal epithelial cells byhydrogen peroxide through NF-kappaB pathway.2006

    • Author(s)
      Shindo K, Iizuka M, Sasaki K, Konno S, Itou H, Horie Y, Watanabe S
    • Journal Title

      J Gastroenterol 41(5)

      Pages: 450-61

    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Hepatic gene ezpression in hepatocyte-specific Pten deficient mice showing steatohepatitis without ethanol challenge2006

    • Author(s)
      Sato W, Horie Y, Kataoka E, Ohshima S, Dohmen T, Iizuka M, Sasaki J, Sasaki M, Hamada K, Kishimoto H, Suzuki A, Watanabe S
    • Journal Title

      HEPATOLOGY RESEARCH 34

      Pages: 256-265

    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Specific type IV phosphodiesterase inhibitor ameliorates thioacetamide-induced liver injury in rats.2005

    • Author(s)
      Matsuhashi T, Otaka M, Odashima M, Jin M, Komatsu K, Konishi N, Wada I, Sato T, Horikawa Y, Ohba R, Oyake J, Hatakeyama N, Watanabe S.
    • Journal Title

      J Gastroenterol Hepatol. 20(1)

      Pages: 135-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590617
  • [Journal Article] Selective adenosine A receptor agonist, ATL-146e, attenuates stress-induced gastric lesions in rats.2005

    • Author(s)
      Odashima M, Otaka M, Jin M, Komatsu K, Wada I, Matsuhashi T, Horikawa Y, Hatakeyama N, Oyake J, Ohba R, Linden J, Watanabe S.
    • Journal Title

      J Gastroenterol Hepatol. 20(2)

      Pages: 275-280

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590617
  • [Journal Article] 非アルコール性脂肪性肝炎:脂肪肝を発症する遺伝子変異マウスを用いた機序の解明2005

    • Author(s)
      渡辺純夫, 堀江泰夫, 他
    • Journal Title

      最新医学 60・4(印刷中)

    • Data Source
      KAKENHI-PROJECT-16590574
  • [Journal Article] Nonalcoholic Steatohepatitis (NASH)への実験医学的アプローチ2005

    • Author(s)
      渡辺純夫, 堀江泰夫, 他
    • Journal Title

      肝臓 45・11

      Pages: 568-580

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590574
  • [Journal Article] Hepatocyte-speci Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma2005

    • Author(s)
      Watanabe S, Horie Y, et al.
    • Journal Title

      Hepatol Res 33

      Pages: 161-166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590574
  • [Journal Article] Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma2005

    • Author(s)
      Watanabe S, Horie Y, et al.
    • Journal Title

      Hepatol Res 33

      Pages: 161-166

    • NAID

      10016809362

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590574
  • [Journal Article] 脂肪肝から肝がんへ・・・NASHの新展開2005

    • Author(s)
      堀江泰夫, 渡辺純夫, 他
    • Journal Title

      内科 (印刷中)

    • Data Source
      KAKENHI-PROJECT-16590574
  • [Journal Article] 脂肪肝から肝がんへ…動物モデルからみたNASHの新展開2005

    • Author(s)
      堀江泰夫, 渡辺純夫, 他
    • Journal Title

      日本内科学会雑誌 94・5

      Pages: 990-998

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590574
  • [Journal Article] Experimental approach to nonalcoholic steatohepatitis (NASH)2004

    • Author(s)
      Watanabe S, Horie Y, et al.
    • Journal Title

      Acta Hepatologica Japonica 45(11)

      Pages: 568-580

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590574
  • [Journal Article] Rolipram, a specific type IV phosphodiesterase inhibitor, ameliorates indomethacin-induced gastric mucosal injury in rats.2003

    • Author(s)
      Nakamura C, Otaka M, Odashima M, Jin M, Konishi N, Horikawa Y, Matsuhashi T, Watanabe S.
    • Journal Title

      Pathophysiology. 9(3)

      Pages: 195-200

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590617
  • [Presentation] 肝脂肪化によるmTOR活性化を介したリソソーム酸性化障害とオートファジー機能抑制2015

    • Author(s)
      中寺英介、山科俊平、渡辺純夫
    • Organizer
      第101回消化器病学会総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2015-04-24
    • Data Source
      KAKENHI-PROJECT-24390191
  • [Presentation] 非アルコール性脂肪性肝疾患患者におけるオートファジー機能障害とカテプシン発現異常2013

    • Author(s)
      福生有華, 山科 俊平, 泉 光輔, 園上 浩司, 荒川 敦, 青山 友則, 内山 明, 今 一義, 鈴木 聡子, 池嶋 健一, 渡辺 純夫
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-24390191
  • [Presentation] 肝細胞内脂肪滴蓄積とオートファジー機能障害2011

    • Author(s)
      山科俊平、稲見義宏、今一義、池嶋健一、渡辺純夫
    • Organizer
      第47回日本肝臓学会総会ワークショップ
    • Place of Presentation
      東京都ホテルグランパシフィック
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] 肝細胞内脂肪滴によるオートファジー機能障害と酸化ストレス2010

    • Author(s)
      稲見義宏、山科俊平、渡辺純夫
    • Organizer
      第18回日本消化器関連学会週間
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-10-14
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] 肥満モデルにおけるオートファジーを介した蛋白分解機能の変化2010

    • Author(s)
      稲見義宏、山科俊平、渡辺純夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      ホテルメトロポリタン山形
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] Loss of autophagy enhances the sensitization of Kupffer cells to endo toxin2010

    • Author(s)
      Hiroo Fukada, Shunhei Yamashina, Kousuke Izumi, Yoshihiro Inami, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
    • Organizer
      The American association for the study of liver diseases 61th annual meeting and postgraduate course# 1971
    • Place of Presentation
      米国ボストンHynes convention center
    • Year and Date
      2010-11-03
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] 肥満モデルにおけるオートファジーを介した蛋白分解機能の変化2010

    • Author(s)
      稲見義宏、山科俊平、渡辺純夫
    • Organizer
      第46回日本肝臓学会総会パネルディスカッション
    • Place of Presentation
      山形県山形テルサホール
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] Lipid accumulation inhibits induction of autophagy in the mouse liver2009

    • Author(s)
      Yoshihiro Inami, Shunhei Yamashina, Kousuke Izumi, Hiroo Fukada, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
    • Organizer
      The American association for the study of liver diseases 60th annual meeting and postgraduate course# 1875
    • Place of Presentation
      日米国ボストンHynes convention center
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] 肝細胞特異的Pten欠損マウスを用いたNASHに対する有効薬剤の検討2007

    • Author(s)
      堀江泰夫, 大嶋重敏, 渡辺純夫
    • Organizer
      JDDW2007
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-20
    • Data Source
      KAKENHI-PROJECT-18590714
  • [Presentation] 肝細胞特異的Pten欠損マウスを用いたNASHに対する有効薬剤の検討

    • Author(s)
      堀江 泰夫、大嶋 重敏、渡辺 純夫
    • Data Source
      KAKENHI-PROJECT-18390213
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  • 2.  IKEJIMA Kenichi (20317382)
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  • 14.  MAEHIRO Kohei (30238878)
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  • 19.  ITOH Hideaki (80168369)
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  • 21.  ODASHIMA Masaru (40375267)
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  • 22.  NAKAJIMA Akihito (30439294)
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