HORIE Yasuo 堀江泰夫

… Alternative Names

Researcher Number	30282164
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016: 秋田大学, 医学系研究科, 講師 2015: 秋田大学, 大学院医学系研究科, 講師 2012 – 2015: 秋田大学, 医学(系)研究科(研究院), 講師 2009 – 2011: Akita University, 大学院・医学系研究科, 講師 2010: 秋田大学, 医学部, 講師 … More
Review Section/Research Field	Principal Investigator Gastroenterology / Experimental pathology Except Principal Investigator Gastroenterology / Metabolomics / Virology / Dermatology / Structural biochemistry
Keywords	Principal Investigator 肝癌 / Pten / イノシトールリン脂質 / NOD1 / ノックアウトマウス / PTEN / 炎症 / 発癌 / autophagosome / autolysosome … More Except Principal Investigator PTEN / Pten遺伝子 / ノックアウトマウス / 酸化ストレス / NASH / イノシトールリン脂質 / 肥満 / 遺伝子治療 / ob/obマウス / Ob / マウス / Obマウス / 急性膵炎 / VAMP7 / オートファジー / トリプシン / ロタウイルス / 非構造タンパク / 遺伝子解析 / エンテロトキシン / 下痢症 / 病原性 / ウイルス性下痢症 / NSP4 / マウスモデル / rotavirus / nonstructural protein / gene analysis / enterotoxin / diarrhea / pathogenesis / 脂肪性肝炎 / 肝発癌 / 抗酸化剤 / N-アセチルシステイン / steatohepatitis / oxidative stress / hepatic caricinogenesis / antioxidant / N-acetyleisteine / 脂肪肝 / 炎症 / 治療薬 / Pten遺伝 / ミトコンドリア / Pten gene / reactive oxygen speies / steatosis / inflammation / therapeutic agent / 壊疽性膿皮症 / 炎症性皮膚疾患 / 細胞内小胞輸送系 / PIPKIII / 細胞内小胞輸送 / 空胞形成 / タモキシフェン / PipkIII / オートファージー / 遺伝子改変マウス / 脱リン酸化酵素 / ホスファターゼ / フォスファターゼ / リン脂質 Less

Pathogenetic machanism for pyoderma gangrenosusm by disruption of the production pathway of phosphatidylinositol (3,5) biphosphate
- Principal Investigator
  
  Hasunuma Naoko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Akita University
The identification of intact PI3P phosphatase and physiological role
- Principal Investigator
  
  EGUCHI SATOSHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Akita University
Identification and functional analysis of SNARE proteins participating in the onset of acute pancreatitis
- Principal Investigator
  
  Ohnishi Hirohide
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
炎症性腸疾患の発症に関わる腸上皮細胞におけるイノシトールリン脂質代謝異常の解明Principal Investigator
- Principal Investigator
  
  堀江泰夫
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
Elucidation of the phosphatidylinositol metabolism to control steatohepatitis and hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  HORIE Yasuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
Study for therapeutic effect of hepatocyte specific Pten deficiency on severe obesity.
- Principal Investigator
  
  OHSHIMA Shigetoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Akita University
Role of lipid and oxidative stress on carcinogenesis in the digestive system
- Principal Investigator
  
  WATANABE Sumio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Autophagy is involved in inflammation, fibrosis, and carcinogenesis-A study using mice modelPrincipal Investigator
- Principal Investigator
  
  HORIE Yasuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
The study of NASH mechanism-in terms of reactive oxygen species and mitochondrial function-
- Principal Investigator
  
  OHSHIMA Shigetoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
The involvement of lipid signaling to the onset and progression of nonalcoholic steatohepatitis and the development of hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  HORIE Yasuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
Functional Analysis of NODI Gene Related with Proliferation, Apoptosis, and Innate Immune Response Using Knockout MicePrincipal Investigator
- Principal Investigator
  
  HORIE Yasuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Akita University
Enterotoxigenic activity of rotavirus NSP4Principal Investigator
- Principal Investigator
  
  NAKAGOMI Toyoko, 堀江泰夫
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  AKITA UNIVERSITY

All 2013 2012 2011 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.2013
- Author(s)
  Takasuga , Wada et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A
  
  Volume: 1726-1731 Pages: 1726-1731
- DOI
  10.1073/pnas.1213212110
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21116002, KAKENHI-PROJECT-21390050, KAKENHI-PROJECT-23229001, KAKENHI-PROJECT-23701036, KAKENHI-PROJECT-24240120, KAKENHI-PROJECT-24390046, KAKENHI-PROJECT-24390067, KAKENHI-PROJECT-24590930, KAKENHI-PROJECT-24657081, KAKENHI-PROJECT-24659084, KAKENHI-PROJECT-24659124, KAKENHI-PROJECT-24770115, KAKENHI-PROJECT-24790734, KAKENHI-PUBLICLY-25113517, KAKENHI-PROJECT-25650066, KAKENHI-PUBLICLY-23113706, KAKENHI-PUBLICLY-23113716, KAKENHI-PUBLICLY-23121505, KAKENHI-PUBLICLY-24112515
[Journal Article] PPARγ contributes to PKM2 and HK2 expression in fatty liver2012
- Author(s)
  Panasyuki, G, Horie Y, 16人中5番目, et al
- Journal Title
  
  Nature Communication
  
  Volume: 3:672 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590823
[Journal Article] PPARγ contributes to PKM2 and HK2 expression in fatty liver2012
- Author(s)
  Panasyuki G, Horie Y, et al
- Journal Title
  
  Nature Communication
  
  Volume: 3 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590823
[Journal Article] Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation.2008
- Author(s)
  Takashi Ueno, Wataru Sato, Yasuo Horie, et. al.
- Journal Title
  
  Autophagy 4(Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590713
[Journal Article] Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation2008
- Author(s)
  Takashi Ueno, Wataru Sato, Yasuo Horie, et. al.
- Journal Title
  
  Autophagy 5(Epub ahead)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590713
[Journal Article] Loss of Pten, a tumor suppressor, causes the strong in inhibition of autophagy without affecting LC3 lipidation2008
- Author(s)
  Takashi, Ueno, Wataru, Sato, Yasuo, Horie, et. al.
- Journal Title
  
  Autophagy 4
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590713
[Journal Article] Non-alcoholic steatohepatitis and hepatocellular carcinoma lessons fromhepatocyte-specific phosphatase and tensin homolog(PTEN)-deficient mice2007
- Author(s)
  Watanabe S, Horie Y, Kataoka E, Sato W, Dohmen T, Ohshima S, Goto T, Suzuki A.
- Journal Title
  
  J.Gastroenterol.Hepatol. 22(Suppl1)
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] Non-alcoholic steatohepatitis and hepatocellular carcinoma : lessons from hepatoeyte-specific phosphatase and tensin homolog (PTEN)-defient mice.2007
- Author(s)
  Watanabe S. Horie Y. Kataoka E. Sato W. Dohmon T. Ohshima S. Goto T. Suzuki A.
- Journal Title
  
  J. Gastroenterol. Hepatol 22 (Suppl 1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] Hepatic gene expression in hepatocyte-specific Pten deficient mice showing Steatohepatitis without ethanol challenge.2006
- Author(s)
  Sato W. Horie Y. Kataoka E. Qhshima S. Dohmen T. Iizuka M. Sasaki J. Sasaki T. Hamada K. Kishimoto H. Suzuki A. Watanabe S.
- Journal Title
  
  Hepatol. Res. 34
  
  Pages: 256-265
- NAID
  10020405034
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] IV. 非アルコール性脂肪性肝炎(NASH)4. NASHの病態解明(実験モデルからのレッスン)2006
- Author(s)
  堀江泰夫, 他
- Journal Title
  
  日本内科学会雑誌 95・1
  
  Pages: 57-65
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] IV.非アルコール性脂肪性肝炎(NASH)4.NASHの病態解明(実験モデルからのレッスン)2006
- Author(s)
  堀江泰夫他
- Journal Title
  
  日本内科学会雑誌 95・1
  
  Pages: 57-65
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Hepatic gene expression in hepatocyte-specific Pten deficient mic showing steatohepatitis without ethanol challenge2006
- Author(s)
  Sato W, Horie Y, et al.
- Journal Title
  
  Hepatol Res Epub ahead of print
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Hepatic gene expression in hepatocyte-specific Pten deficient mice showing steatohepatitis without ethanol challenge2006
- Author(s)
  Sato W, Horie Y, et al.
- Journal Title
  
  Hepatol Res (Epub ahead of print)
- NAID
  10020405034
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Rotavirus double-stranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells.2006
- Author(s)
  Sato A, Iizuka M, Nakagomi O, Suzuki M, Horie Y, Konno S, Hirasawa F, Sasaki K, Shindo K, Watanabe S
- Journal Title
  
  J Gastroentrol Hepatol 21(3)
  
  Pages: 521-30
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] Infliximab as a treatment for systemic amyloidosis associeted with Crohn's disease.2006
- Author(s)
  Iizuka M, Konno S, Horie Y, Itou H, Shindo K, Watanabe S
- Journal Title
  
  Gut 55(5)
  
  Pages: 744-5
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] Sucralfate prevents the delay of wound repair in intestinal epithelial cells byhydrogen peroxide through NF-kappaB pathway.2006
- Author(s)
  Shindo K, Iizuka M, Sasaki K, Konno S, Itou H, Horie Y, Watanabe S
- Journal Title
  
  J Gastroenterol 41(5)
  
  Pages: 450-61
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] Hepatic gene ezpression in hepatocyte-specific Pten deficient mice showing steatohepatitis without ethanol challenge2006
- Author(s)
  Sato W, Horie Y, Kataoka E, Ohshima S, Dohmen T, Iizuka M, Sasaki J, Sasaki M, Hamada K, Kishimoto H, Suzuki A, Watanabe S
- Journal Title
  
  HEPATOLOGY RESEARCH 34
  
  Pages: 256-265
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] IV. Nonalcoholic steatohepatitis (NASH) 4. Elucidation of NASH pathogenesis using an experimental model2006
- Author(s)
  Horie Y, et al.
- Journal Title
  
  Internal Med 95(1)
  
  Pages: 57-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] 非アルコール性脂肪性肝炎:脂肪肝を発症する遺伝子変異マウスを用いた機序の解明2005
- Author(s)
  渡辺純夫, 堀江泰夫, 他
- Journal Title
  
  最新医学 60・4(印刷中)
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Nonalcoholic Steatohepatitis (NASH)への実験医学的アプローチ2005
- Author(s)
  渡辺純夫, 堀江泰夫, 他
- Journal Title
  
  肝臓 45・11
  
  Pages: 568-580
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Hepatocyte-speci Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma2005
- Author(s)
  Watanabe S, Horie Y, et al.
- Journal Title
  
  Hepatol Res 33
  
  Pages: 161-166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] DNAマイクロアレイを用いた肝細胞特異的Pten欠損マウスの肝臓における遺伝子発現の検討 -非アルコール性脂肪性肝炎の発症に関る新たな遺伝子の検索を目的として-2005
- Author(s)
  片岡英, 堀江泰夫他
- Journal Title
  
  秋田医学 32・1
  
  Pages: 41-51
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma2005
- Author(s)
  Watanabe S, Horie Y, et al.
- Journal Title
  
  Hepatol Res 33
  
  Pages: 161-166
- NAID
  10016809362
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] NAFLDの成因 NASH病変を呈する遺伝子改変マウスにおける肝発癌機構2005
- Author(s)
  堀江泰夫他
- Journal Title
  
  細胞 37・9
  
  Pages: 352-356
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] 脂肪肝から肝がんへ・・・NASHの新展開2005
- Author(s)
  堀江泰夫, 渡辺純夫, 他
- Journal Title
  
  内科 (印刷中)
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] hepatocellular carcinoma ・・・ New development of NASH pathogenesis in the view of an animal model2005
- Author(s)
  Horie Y, et al.
- Journal Title
  
  Internal Med 94(5)
  
  Pages: 990-998
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] 非アルコール性脂肪性肝炎(NASH)とPTEN遺伝子2005
- Author(s)
  佐藤亘, 堀江泰夫他
- Journal Title
  
  日本臨床 63・8
  
  Pages: 1475-1483
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] 脂肪肝から肝がんへ…動物モデルからみたNASHの新展開2005
- Author(s)
  堀江泰夫, 渡辺純夫, 他
- Journal Title
  
  日本内科学会雑誌 94・5
  
  Pages: 990-998
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Experimental approach to nonalcoholic steatohepatitis (NASH)2004
- Author(s)
  Watanabe S, Horie Y, et al.
- Journal Title
  
  Acta Hepatologica Japonica 45(11)
  
  Pages: 568-580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas2004
- Author(s)
  Yasuo Horie, et al.
- Journal Title
  
  J Clin Invest 113(12)
  
  Pages: 1774-1783
- NAID
  120004837332
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas2004
- Author(s)
  Yasuo Horie, et al.
- Journal Title
  
  J Clin Invest 113・12
  
  Pages: 1774-1783
- NAID
  120004837332
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590574
[Journal Article] Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas2004
- Author(s)
  Yasuo Horie, et al.
- Journal Title
  
  The Journal of Clinical Investigation 113・12
  
  Pages: 1774-1783
- NAID
  120004837332
- Data Source
  KAKENHI-PROJECT-16590574
[Presentation] 腸上皮細胞特異的PipkIII欠損マウスの腸炎と腸線維化の発症機序の解析2013
- Author(s)
  堀江泰夫、真嶋浩聡、大西洋英
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  かごしま県民交流センター（鹿児島県）
- Data Source
  KAKENHI-PROJECT-24590930
[Presentation] Contribution of intestinal bacteria and epithelial mesenchymal transition to intestinal inflammation and fibrosis in enterocyte-specific Pipk III deficient mice2012
- Author(s)
  Horie Y, Takasuga S, Sasaki T, Ohnishi H
- Organizer
  Digestive Disease Weak
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Data Source
  KAKENHI-PROJECT-24590930
[Presentation] 肝細胞特異的Pten欠損によるレプチン欠損ob/obマウスの肥満の改善2011
- Author(s)
  大嶋重敏,堀江泰夫,後藤隆,三浦光一,澁谷友美,佐藤亘,道免孝洋,姉崎有美子,山田育弘,鎌田健太郎,鈴木聡,大西洋英
- Organizer
  肝臓病学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-20591041
[Presentation] Hepatocyte-specific Pten deficiency improves obesity in the leptin-deficient ob/ob mouse.2011
- Author(s)
  Shigetoshi Ohshima, Yasuo Horie, Takashi Goto, Kouichi Miura, Akira Suzuki, Hirohide Ohnishi
- Organizer
  DDW2011
- Place of Presentation
  Chicago
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-20591041
[Presentation] Steatohepatitis and hepatocellular carcinoma developed in hepatocyte-specific Pten-deficient mice2011
- Author(s)
  Yasuo Horie, et al
- Organizer
  The 9^<th> JSH Single Topic Conference (日本肝臓学会)
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21590823
[Presentation] N-acetyl-L-cystein blocks progression of NASH by reducing reactive oxygen species-An examination using patocyte-specific Pten deficient mice2007
- Author(s)
  Shigetoshi Ohshima, Yasuo HorieTakahiro Domen, et. al.
- Organizer
  Liver disease society.(EASL)
- Year and Date
  2007-04-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590714
[Presentation] Eicosapentaenoic acid improve steatohepatitis in newly established mice Model of nonalcoholic steatohepatitis2007
- Author(s)
  Hajime Ishii, Yasuo Horie, Shigetoshi Ohshima et.al
- Organizer
  ヨーロッパ肝臓病学会(EASL)
- Place of Presentation
  スペイン,バルセロナ
- Year and Date
  2007-04-17
- Data Source
  KAKENHI-PROJECT-18590714
[Presentation] 肝細胞特異的Pten欠損マウスを用いたNASHに対する有効薬剤の検討2007
- Author(s)
  堀江泰夫, 大嶋重敏, 渡辺純夫
- Organizer
  JDDW2007
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-18590714
[Presentation] N-acetyl-L-cystein blocks progression of NASH by reducing reactive oxygen species-An examination using hepatocyte-specific Pten deficient mice-2007
- Author(s)
  Shigetoshi, Ohshima, Yasuo, Horie, Takahiro, Domen, et. al
- Organizer
  ヨーロッパ肝臓病学会(EASL)
- Place of Presentation
  スペイン,バルセロナ
- Year and Date
  2007-04-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590714
[Presentation] 肝細胞特異的Pten欠損マウスを用いたNASHに対する有効薬剤の検討
- Author(s)
  堀江泰夫、大嶋重敏、渡辺純夫
- Data Source
  KAKENHI-PROJECT-18390213

1. OHSHIMA Shigetoshi (50375268)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. WATANABE Sumio (20138225)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
3. OHNISHI Hirohide (00313023)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. SASAKI Takehiko (50333365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKAGOMI Toyoko (40155693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MASHIMA Hirosato (10261869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIURA Kouichi (90375238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAGOMI Osamu (70143047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IMAGAWA Tadashi (10036478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUKI Akira (10311565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IKEJIMA Kenichi (20317382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Hasunuma Naoko (10282170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Manabe Motomu (30138309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. EGUCHI SATOSHI (70457117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. MOCHIZUKI Masami

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUZUKI Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KAGAYA Masami

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KOFUJI Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 和田洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 高須賀俊輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 木村洋貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HORIE Yasuo 堀江 泰夫

堀江 泰天 ホリエ ヤスオ

堀江 泰夫 ホリエ ヤスオ

Research Projects

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Pathogenetic machanism for pyoderma gangrenosusm by disruption of the production pathway of phosphatidylinositol (3,5) biphosphate

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The identification of intact PI3P phosphatase and physiological role

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Identification and functional analysis of SNARE proteins participating in the onset of acute pancreatitis

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炎症性腸疾患の発症に関わる腸上皮細胞におけるイノシトールリン脂質代謝異常の解明Principal Investigator

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Elucidation of the phosphatidylinositol metabolism to control steatohepatitis and hepatocellular carcinomaPrincipal Investigator

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Study for therapeutic effect of hepatocyte specific Pten deficiency on severe obesity.

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Role of lipid and oxidative stress on carcinogenesis in the digestive system

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Autophagy is involved in inflammation, fibrosis, and carcinogenesis-A study using mice modelPrincipal Investigator

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The study of NASH mechanism-in terms of reactive oxygen species and mitochondrial function-

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The involvement of lipid signaling to the onset and progression of nonalcoholic steatohepatitis and the development of hepatocellular carcinomaPrincipal Investigator

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Functional Analysis of NODI Gene Related with Proliferation, Apoptosis, and Innate Immune Response Using Knockout MicePrincipal Investigator

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Enterotoxigenic activity of rotavirus NSP4Principal Investigator

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[Journal Article] Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.2013

Author(s)

HORIE Yasuo 堀江泰夫

堀江泰天ホリエヤスオ

堀江泰夫ホリエヤスオ