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Ikejima Kenichi  池嶋 健一

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IKEJIMA Kenichi  池嶋 健一

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Researcher Number 20317382
Other IDs
External Links
Affiliation (Current) 2022: 順天堂大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2017 – 2021: 順天堂大学, 医学部, 教授
2016: 順天堂大学, 医学部, 先任准教授
2011 – 2015: 順天堂大学, 医学(系)研究科(研究院), 准教授
2014: 順天堂大学, 医学研究科, 准教授
2014: 順天堂大学, 医学部, 准教授 … More
2013: 順天堂大学, 消化器内科, 准教授
2011 – 2012: 順天堂大学, 医学研究科, 准教授
2011: 順天堂大学, 医学(系)・研究科(研究院), 准教授
2007 – 2011: Juntendo University, Dept. of Gastroenterology, Associate Prof
2002 – 2006: Dept. of Gastroenterology, Juntendo Univ. School of Medicine, Assistant Professor, 医学部, 講師
2005: 医学部, 講師
1999 – 2001: 順天堂大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Gastroenterology / Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
自然免疫 / メタボリックシンドローム / NKT細胞 / レプチン / 肝線維化 / Kupffer細胞 / 肝星細胞 / TNF-α / アディポネクチン / 肝再生 … More / 非アルコール性脂肪肝炎(NASH) / 免疫栄養 / アミノ酸 / 非アルコール性脂肪性肝炎 / エンドトキシン肝障害 / ICAM-1 / 脂肪肝 / 細胞外基質 / TGF-β / 肝類洞内皮細胞 / 肝臓病学 / 脂肪性肝炎 / PPAR / ピオグリタゾン / STAT-3 / PPAR-γ / 非アルコール性脂肪肝炎(NASH) / NK細胞 / CD1d / アディポカイン / チアゾリジン系誘導体 / 制御性T細胞 / グリシン / 非アルコール性脂肪性肝疾患 / 非アルコール性脂肪肝炎 / Th2サイトカイン / 肝発癌 / 脂肪性肝疾患 / NASH / C型慢性肝炎 / アディポサイトカイン / アディポネクチンン / インターフェロン / 低分子量ヘパリン / 抗ウイルス療法 / アポトーシス / 肝類洞壁細胞 / adipocytokines / leptin / adiponectin / nonalcoholic steatohepatitis (NASH) / chronic hepatitis C / interferon / hepatic fibrogenesis / 非アルコール性脂肪肝炎(NASH) / 腸内マイクロバイオーム / 耐糖能異常 / 糖代謝 / インスリン / 腸内細菌叢 / RIG-I / 代謝障害性脂肪性肝疾患(MAFLD) / 腸肝相関 / サイトカインストーム / 日本食 … More
Except Principal Investigator
酸化ストレス / オートファジー / 肝線維化 / 肝再生 / アポトーシス / インスリン抵抗性 / NASH / TNF-α / エンドトキシン / アルコール性肝障害 / 肝星細胞 / 薬物性肝障害 / NAFLD / TNFα / 肝障害 / 細胞死 / 炎症 / 脂肪性肝炎 / リソソーム / バイオマーカー / 肝癌 / 非アルコール脂肪肝炎 / 遊離脂肪酸 / グリシン / 炎症性腸疾患 / ケモカイン / 類洞内皮細胞 / マクロファージ / glycine / Toll-like receptor (TLR) / 老化 / PTEN / 非アルコール性脂肪肝炎 / 脂肪毒性 / inverse genomics / リボザイムライブラリ / siRNAライブラリ / 肝マクロファージ / 腸管透過性 / CRP / アセトアミノフェン / ネクローシス / ROS / 血管新生 / エイコサペンタエン酸 / ミトコンドリア / 潰瘍性大腸炎 / 核膜蛋白 / 肝疾患 / 脂肪性肝疾患 / カテプシン / 慢性肝炎 / エピジェネティクス / 化学シャペロン / トランス脂肪酸 / 小胞体ストレス / 肝細胞がん / カルニチン / 肝細胞癌 / 脂肪肝 / 高脂肪食 / 食事療法 / 運動療法 / アミノ酸 / TNBS腸炎 / 腸管 / 免疫薬理学的栄養作用 / Amino acids / inflammatory bowel disease / TNBS colitis / chemokine / 腸内細菌 / 炎病性腸疾患 / Kupffer細胞 / CD14 / Toll-like receptor / Toll-like receotor(Tlr) / LPS binding protein / Toll-like receptor(Tlr) / bacterial toxins / innate immunity / alcoholic liver disease / inflammatory bowel diseases / macrophages / SMP30 / 肝細胞 / SMP 30 / apoptosis / liver / レプチン / アディポネクチン / メタボリックシンドローム / 肝類洞壁細胞 / 炎症性サイトカイン / PPAR-γ / fatty liver / hepatic fibrogenesis / adipokines / leptin / adiponectin / TGF-β / hepatic stellate cells / insulin resistance / ヒアルロン酸 / ヒアルロン酸グラフト化ポリLリジン / 遺伝子デリバリ / 相分離性ナノ会合体 / デコイ法 / 3重鎖核酸法 / ヒアルロン酸グラフト化ポリLリジン櫛型共重合体 / リホザイムライブラリ / 再生 / ヒアルロン酸グラフト化ポリLリジン櫛形共重合体 / ステルス効果 / sinusoidal endothelial cells / gene delivery / triplex DNA / 肝発癌 / 抗酸化剤 / N-アセチルシステイン / steatohepatitis / oxidative stress / hepatic caricinogenesis / antioxidant / N-acetyleisteine / リピドラフト / 核マトリクス蛋白 / 膵癌 / 核マトリクス / 膵炎 / ジェントロジー / サルコペニア / リピドミクス / ヘパトカイン / 脂質代謝 / ユビキチン化 / ジエントロジー / ジェロントロジー / 脂質 / 筋肝連関 / 肝がん / 脂質合成 / 脂肪酸不飽和化酵素 / 抗酸化物質 / 脂肪酸代謝 Less
  • Research Projects

    (24 results)
  • Research Products

    (329 results)
  • Co-Researchers

    (34 People)
  •  Immunonutritional approach for innate immune dysregulation in metabolic dysfunction-associated fatty liver diseasePrincipal Investigator

    • Principal Investigator
      池嶋 健一
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Juntendo University
  •  Mechanism of enhanced hepatotoxicity through fatty acid metabolic imbalance in the progression of fatty liver disease

    • Principal Investigator
      今 一義
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Juntendo University
  •  The impact of lipid composition alteration via beta-oxidation failure on the pathophysiological linkage between nonalcoholic steatohepatitis and sarcopenia

    • Principal Investigator
      Kon Kazuyoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Development of an early diagnosis method targeting nuclear matrix protein for autophagy-related digestive disorder disease

    • Principal Investigator
      WATANABE SUMIO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Palmitic acid elicits insulin resistance and oxidative cell injury through clusterization of lipid rafts in murine hepatocytes.

    • Principal Investigator
      Uchiyama Akira
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Innate immune regulation in metabolic steatohepatitis and experimental therapeuticsPrincipal Investigator

    • Principal Investigator
      Ikejima Kenichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  New therapeutic strategy to non-alcoholic liver disease targeting on autophagy

    • Principal Investigator
      WATANEBE Sumio
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  The new strategy of steatohepatitis targeting alteration of epigenetic regulation

    • Principal Investigator
      KON Kazuyoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Innate immune regulation of hepatic metabolism and immuno-nutritional approach for nonalcoholic fatty liver diseasePrincipal Investigator

    • Principal Investigator
      IKEJIMA Kenichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Novel biomarker for evaluation of autophagic dysfunction in the liver

    • Principal Investigator
      YAMASHINA SHUNHEI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Central role of autophagy in the pathogenesis of gastrointestinal and hepatic diseases.

    • Principal Investigator
      WATANABE Sumio
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Role of innate immune system in the regulation of hepatic metabolism and pathogenesis of steatohepatitisPrincipal Investigator

    • Principal Investigator
      IKEJIMA Kenichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Role of autophagy in liver diseases

    • Principal Investigator
      YAMASHINA Shunhei
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Pathogenesis and experimental therapeutics of metabolic syndrome-related liver diseasesPrincipal Investigator

    • Principal Investigator
      IKEJIMA Kenichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Role of lipid and oxidative stress on carcinogenesis in the digestive system

    • Principal Investigator
      WATANABE Sumio
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  消化管・肝機能枢軸から見た薬物性肝障害機序の解明

    • Principal Investigator
      鈴木 聡子
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Role of adipocytokine in progression and therapeutic resistance in chronic liver diseases and hepatocellular carcinomaPrincipal Investigator

    • Principal Investigator
      IKEJIMA Kenichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Investigation of pathophysiology and therapeutic strategies for metabolic syndrome-related steatohepatitis

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Genetic Manipulation of Sinusoidal Endothelial Cells

    • Principal Investigator
      TAKEI Yoshiyuki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Inverse genomicsを用いた肝線維化に関わる遺伝子の網羅的探索

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  肝臓におけるleptinの産生およびその病態生理的意義Principal Investigator

    • Principal Investigator
      池嶋 健一
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Innate immune response to gut-derived bacterial toxins in gastrointestinal andhepatic disorders

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine
  •  ROLE OF SENESCENCE MARKER PROTEIN-30 (SMP30) IN HEPATOCYTE APOPTOSIS

    • Principal Investigator
      KITAMURA Tsuneo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      JUNTENDO UNIVERSITY
  •  Amino acids as immuno-moduratory nutrients: therapeutic approaches for gastrointestinal and hepatic disorders.

    • Principal Investigator
      TAKEI Yoshiyuki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] アルコールと医学生物学「非B非C肝癌におけるオートファジー関連蛋白発現の変化」2014

    • Author(s)
      今一義、池嶋健一、渡辺純夫
    • Total Pages
      4
    • Publisher
      東洋書店
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Book] 消化器の臨床 「NAFLD/NASHの病態と適切な診療を知る NAFLD/NASHの成因と病態」2014

    • Author(s)
      森永真紀、今一義、池嶋健一、渡辺純夫
    • Total Pages
      6
    • Publisher
      ヴァンメディカル
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Book] 今日の治療指針 2013年版2013

    • Author(s)
      池嶋健一
    • Publisher
      アルコール性肝障害
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Book] アラキドン酸側鎖含有合成脂質8A8によるエンドトキシン肝障害の抑制効果.アルコールと医学生物学2010

    • Author(s)
      池嶋健一, 朴南哲, 今一義, 青山友則, 山科俊平, 竹井謙之, 佐藤信紘, 渡辺純夫
    • Publisher
      東洋書店
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Book] 第8章肝疾患10.脂肪肝,脂肪性肝炎.医学スーパーラーニングシリーズ消化器内科学2010

    • Author(s)
      池嶋健一, 渡辺純夫
    • Publisher
      シュプリンガー・ジャパン
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Book] 一般演題10トランス脂肪酸による肝細胞内脂肪貯留と酸化ストレス応答性の亢進第6回「酸化ストレスと肝」研究会記録酸化ストレスと肝疾患2010

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Publisher
      メディカルトリビューン
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Book] 脂肪性肝炎における肝再生不全に対するpioglitazoneの改善効果.アルコールと医学生物学2009

    • Author(s)
      青山友則, 池嶋健一, 今一義, 山形寿文, 山科俊平, 佐藤信紘, 渡辺純夫
    • Publisher
      東洋書店
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Book] セッション5-肝疾患と酸化ストレス2-一般演題13. メタボリック症候群における肝再生不全 : pioglitazoneによる改善効果とそのメカニズム. 酸化ストレスと肝疾患第5巻谷川久一編2009

    • Author(s)
      青山友則, 池嶋健一, 今一義, 奥村京子, 渡辺純夫
    • Publisher
      メディカルトリビューン, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] セッション5-肝疾患と酸化ストレス2-一般演題13.メタボリック症候群における肝再生不全: pioglitazoneによる改善効果とそのメカニズム.酸化ストレスと肝疾患2009

    • Author(s)
      青山友則, 池嶋健一, 今一義, 奥村京子, 渡辺純夫
    • Publisher
      メディカルトリビューン
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Book] 脂肪性肝炎における肝再生不全に対するpioglitazoneの改善効果. アルコールと医学生物学Vol.28, アルコール医学生物学研究会編2009

    • Author(s)
      青山友則, 池嶋健一, 今一義, 山形寿文, 山科俊平, 佐藤信紘, 渡辺純夫
    • Publisher
      東洋書店, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] IV主要疾患の診断と治療B. 肝疾患8. 非アルコール性脂肪性肝疾患・脂肪性肝炎. 消化器内科レジデントハンドブック渡辺純夫, 北條麻理子編2008

    • Author(s)
      池嶋健一
    • Publisher
      中外医学社, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] II検査の実際11. 腹腔鏡, 肝生検. 消化器内科レジデントハンドブック渡辺純夫, 北條麻理子編2008

    • Author(s)
      池嶋健一
    • Publisher
      中外医学社, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] II章肝・胆・膵【1】肝臓I. NAFLDとNASH. 専門医のための薬物療法Q&A消化器渡辺純夫三輪洋人編2008

    • Author(s)
      池嶋健一
    • Publisher
      中外医学社, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] IV主要疾患の診断と治療B. 肝疾患1. 肝機能異常. 消化器内科レジデントハンドブック渡辺純夫, 北條麻理子編2008

    • Author(s)
      池嶋健一
    • Publisher
      中外医学社, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] 6. 治療2. 酸化ストレス. NASH診療best approach西原利治編2008

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Publisher
      中外医学社, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] 女性・高齢者と飲酒アルコール医学・医療における性差. 別冊・医学のあゆみアルコール医学・医療の最前線竹井謙之編2008

    • Author(s)
      池嶋健一
    • Publisher
      医歯薬出版株式会社, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] 一般演題/411. 酸化ストレスに伴う肝細胞傷害における鉄イオンの細胞内動態と細胞死への影響. 酸化ストレスと肝疾患第4巻谷川久一編2008

    • Author(s)
      内山明, 池嶋健一, 今一義, 渡辺純夫
    • Publisher
      メディカル・ジャーナル社, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] アルコール性肝障害発症における代謝性素因の関与 : KK-Ayマウスを用いた検討. アルコールと医学生物学Vol.27, アルコール医学生物学研究会編2007

    • Author(s)
      池嶋健一, 今一義, 奥村京子, 青山友則, 竹井謙之, 佐藤信紘, 渡辺純夫
    • Publisher
      東洋書店, 東京
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] 研究報告/I. 病態メタボリックシンドロームにおける酸化ストレス刺激に伴う肝障害増悪の検討. 酸化ストレスと肝疾患第3巻アークメディア, 東京(谷川久一編)2007

    • Author(s)
      今一義, 池嶋健一, 奥村京子, 青山友則, 渡辺純夫
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Book] Role of leptin in pathogenesis of NASH, In Frontiers in Hepatology.(Okita K, Ed.)2005

    • Author(s)
      Ikejima K, Lang T, Yamashina S, Enomoto N, Takai Y, Sato N.
    • Publisher
      Springer-Verlag, Tokyo
    • Data Source
      KAKENHI-PROJECT-14657136
  • [Book] Genetic manipulation of liver sinusoidal endothelial cells. In Organ Microcirculation : A gateway to diagnostic and therapeutic interventions.2004

    • Author(s)
      Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
    • Publisher
      Springer-Verlag, Tokyo
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Aging exacerbates high-fat diet-induced steatohepatitis through alteration in hepatic lipid metabolism in mice2020

    • Author(s)
      Ishizuka Kei、Kon Kazuyoshi、Lee‐Okada Hyeon‐Cheol、Arai Kumiko、Uchiyama Akira、Yamashina Shunhei、Yokomizo Takehiko、Ikejima Kenichi
    • Journal Title

      journal of gastroenterology and hepatology

      Volume: In press Pages: 1437-1448

    • DOI

      10.1111/jgh.15006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19KK0199, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-17K09440, KAKENHI-PROJECT-20K17032
  • [Journal Article] Cathepsin L-deficiency enhances liver regeneration after partial hepatectomy2019

    • Author(s)
      Sato Toshifumi、Yamashina Shunhei、Izumi Kosuke、Ueno Takashi、Koike Masato、Ikejima Kenichi、Peters Christoph、Watanabe Sumio
    • Journal Title

      Life Sciences

      Volume: 221 Pages: 293-300

    • DOI

      10.1016/j.lfs.2019.02.040

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-18K08016, KAKENHI-PROJECT-16H05293
  • [Journal Article] The Chemical Chaperone 4‐Phenylbutyric Acid Prevents Alcohol‐Induced Liver Injury in Obese KK‐A y Mice2019

    • Author(s)
      Suzuki Maiko、Kon Kazuyoshi、Ikejima Kenichi、Arai Kumiko、Uchiyama Akira、Aoyama Tomonori、Yamashina Shunhei、Ueno Takashi、Watanabe Sumio
    • Journal Title

      Alcoholism: Clinical and Experimental Research

      Volume: 43 Pages: 617-27

    • DOI

      10.1111/acer.13982

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Journal Article] Rifaximin prevents ethanol-induced liver injury in obese KK-Ay mice through modulation of small intestinal microbiota signature2019

    • Author(s)
      Kitagawa Ryuta、Kon Kazuyoshi、Uchiyama Akira、Arai Kumiko、Yamashina Shunhei、Kuwahara-Arai Kyoko、Kirikae Teruo、Ueno Takashi、Ikejima Kenichi
    • Journal Title

      American Journal of Physiology-Gastrointestinal and Liver Physiology

      Volume: 317

    • DOI

      10.1152/ajpgi.00372.2018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Journal Article] Progress in research of NASH2018

    • Author(s)
      渡辺純夫,今一義,池嶋健一
    • Journal Title

      Nippon Shokakibyo Gakkai Zasshi

      Volume: 115 Issue: 1 Pages: 1-9

    • DOI

      10.11405/nisshoshi.115.1

    • NAID

      130006316870

    • ISSN
      0446-6586, 1349-7693
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Journal Article] Formation of p62-positive inclusion body is associated with macrophage polarization in non-alcoholic fatty liver disease.2018

    • Author(s)
      Fukushima H, Yamashina S, Arakawa A, Taniguchi G, Aoyama T, Uchiyama A, Kon K, Ikejima K, Watanabe S.
    • Journal Title

      Hepatol Res.

    • DOI

      10.1111/hepr.13071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Journal Article] Formation of p62-positive inclusion body is associated with macrophage polarization in non-alcoholic fatty liver disease2018

    • Author(s)
      Fukushima Hirofumi、Yamashina Shunhei、Arakawa Atsushi、Taniguchi Gentaro、Aoyama Tomonori、Uchiyama Akira、Kon Kazuyoshi、Ikejima Kenichi、Watanabe Sumio
    • Journal Title

      Hepatology Research

      Volume: Feb 23

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09022
  • [Journal Article] Spleen-derived lipocalin-2 in the portal vein regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice.2017

    • Author(s)
      Aoyama T, Kuwahara-Arai K, Uchiyama A, Kon K, Okubo H, Yamashina S, Ikejima K, Kokubu S, Miyazaki A, Watanabe S.
    • Journal Title

      Lab Invest.

      Volume: 97 Pages: 890-902

    • DOI

      10.1038/labinvest.2017.44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09023, KAKENHI-PROJECT-15K19350
  • [Journal Article] A Customized Online Nutrition Guidance System Is Effective for Treating Patients with Nonalcoholic Fatty Liver Disease by Supporting Continuity of Diet Therapy at Home: A Pilot Study2017

    • Author(s)
      Aoyama T, Takada H, Uchiyama A, Kon K, Yamashina S, Ikejima K, Ban H, Watanabe S.
    • Journal Title

      Internal Medicine

      Volume: 56 Issue: 13 Pages: 1651-1656

    • DOI

      10.2169/internalmedicine.56.8187

    • NAID

      130006858091

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Journal Article] Sodium 4-phenylbutyric acid prevents murine acetaminophen hepatotoxicity by minimizing endoplasmic reticulum stress.2017

    • Author(s)
      Kusama H, Kon K, Ikejima K, Arai K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S.
    • Journal Title

      J Gastroenterol.

      Volume: 52 Pages: 611-622

    • DOI

      10.1007/s00535-016-1256-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Journal Article] A Customized Online Nutrition Guidance System Is Effective for Treating Patients with Nonalcoholic Fatty Liver Disease by Supporting Continuity of Diet Therapy at Home: A Pilot Study.2017

    • Author(s)
      Supporting Continuity of Diet Therapy at Home: A Pilot Study. Aoyama T, Takada H, Uchiyama A, Kon K, Yamashina S, Ikejima K, Ban H, Watanabe S.
    • Journal Title

      Intern Medcine

      Volume: 56(13) Pages: 1651-1656

    • NAID

      130006858091

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09022
  • [Journal Article] L-carnitine prevents metabolic steatohepatitis in obese diabetic KK-Ay mice.2017

    • Author(s)
      Kon K, Ikejima K, Morinaga M, Kusama H, Arai K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S
    • Journal Title

      Hepatol Res.

      Volume: Apr Pages: 44-54

    • DOI

      10.1111/hepr.12720

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09022, KAKENHI-PROJECT-15K09023
  • [Journal Article] Inhibition of mTOR improves the impairment of acidification in autophagic vesicles caused by hepatic steatosis.2016

    • Author(s)
      Nakadera E, Yamashina S, Izumi K, Inami Y, Sato T, Fukushima H, Kon K, Ikejima K, Ueno T, Watanabe S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 469(4) Pages: 1104-10

    • DOI

      10.1016/j.bbrc.2015.12.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Journal Article] Glycine prevents metabolic steatohepatitis in diabetic KK-Ay mice through modulation of hepatic innate immunity.2016

    • Author(s)
      Takashima S, Ikejima K, Arai K, Yokokawa J, Kon K, Yamashina S, Watanabe S.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 311

    • DOI

      10.1152/ajpgi.00465.2015

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Journal Article] Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.2015

    • Author(s)
      Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M,
    • Journal Title

      J Gastroenterol.

      Volume: 50(4) Pages: 364-377

    • DOI

      10.1007/s00535-015-1050-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590981, KAKENHI-PROJECT-24590996, KAKENHI-PROJECT-25460999, KAKENHI-PROJECT-26461010, KAKENHI-PROJECT-15K09009, KAKENHI-PROJECT-15K09010, KAKENHI-PROJECT-15K09023, KAKENHI-PROJECT-26461011
  • [Journal Article] Sodium 4-phenylbutyrate prevents murine dietary steatohepatitis caused by <i>trans</i>-fatty acid plus fructose2015

    • Author(s)
      Morinaga M, Kon K, Saito H, Arai K, Kusama H, Uchiyama A, Yamashina S, Ikejima K, Watanabe S.
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: Nov;57(3) Issue: 3 Pages: 183-191

    • DOI

      10.3164/jcbn.15-75

    • NAID

      130005106455

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09022, KAKENHI-PROJECT-15K09023
  • [Journal Article] Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.2015

    • Author(s)
      Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M, Takei Y, Takehara T, Tokushige K, Nakajima A, Yoneda M, Saibara T, Shiota G, Sakaida I, Nakamuta M, Mizuta T, Tsubouchi H, Sugano K, Shimosegawa T.
    • Journal Title

      Hepatol Res

      Volume: 45 Pages: 363-377

    • DOI

      10.1111/hepr.12511

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590996, KAKENHI-PROJECT-15K09009, KAKENHI-PROJECT-26461010, KAKENHI-PROJECT-26461011, KAKENHI-PROJECT-25460999
  • [Journal Article] NAFLDの診療・研究の進歩.2014

    • Author(s)
      池嶋健一,渡辺純夫.
    • Journal Title

      日本消化器病学会雑誌

      Volume: 111 Pages: 4-13

    • NAID

      130003383342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Journal Article] 特集・NAFLD/NASHと肝発癌-その実態と適切な診療に迫る-[NAFLD/NASHの病態と適切な診療を知る]NAFLD/NASHの成因と病態.2014

    • Author(s)
      森永真紀,今一義,池嶋健一,渡辺純夫.
    • Journal Title

      消化器の臨床

      Volume: 17 Pages: 19-24

    • Data Source
      KAKENHI-PROJECT-24590996
  • [Journal Article] Abnormality of autophagic function and cathepsin expression in the liver from patients with non-alcoholic fatty liver disease2014

    • Author(s)
      Yuka Fukuo, Shunhei Yamashina, Hiroshi Sonoue, Atsushi Arakawa, Eisuke Nakadera, Tomonori Aoyama, Akira Uchiyama, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
    • Journal Title

      Hepatol Res.

      Volume: 未定 Pages: 1026-1036

    • DOI

      10.1111/hepr.12282

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590989, KAKENHI-PROJECT-24390191, KAKENHI-PROJECT-24590995, KAKENHI-PROJECT-24590996
  • [Journal Article] 特集:生活習慣病とNKT細胞-病態モジュレーターの面から 非アルコール性脂肪肝炎の病態形成におけるNKT細胞の関与.2013

    • Author(s)
      池嶋健一,渡辺純夫.
    • Journal Title

      医学のあゆみ

      Volume: 246 Pages: 235-240

    • Data Source
      KAKENHI-PROJECT-24590996
  • [Journal Article] Altered expression and function of hepatiic natural killer T cells in obese and diabetic KK-Ay mice.2013

    • Author(s)
      Yamagata H
    • Journal Title

      Hepatol. Res.

      Volume: 43 Pages: 276-288

    • DOI

      10.1111/j.1872-034x.2012.01062.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-24590995, KAKENHI-PROJECT-24590996
  • [Journal Article] Innate Immune responses involving natural killer and natural killer T cells promote liver regeneration after partial hepatctomy in mice.2013

    • Author(s)
      Hosoya S.Ikejima K.Takeda K.Arai K.Ishikawa S.Yamagata H.Aoyama T.Kon K.Yamashina S.Kon K.Watanabe S.
    • Journal Title

      Am. J. Physiol. Gastrointest. Liver Physiol.

      Volume: 304

    • DOI

      10.1152/ajpgi.00083.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590995, KAKENHI-PROJECT-24590996
  • [Journal Article] 特集:NASH-病態と治療,8.NAFLD/NASHの治療(3) 脂質代謝改善薬による治療.2013

    • Author(s)
      池嶋健一
    • Journal Title

      臨床消化器内科

      Volume: 28 Pages: 487-493

    • Data Source
      KAKENHI-PROJECT-24590996
  • [Journal Article] Loss of autophagy promotes murine acetaminophen hepatotoxicity.2012

    • Author(s)
      Igusa Y, Yamashina S, et al
    • Journal Title

      J. Gastroenterol.

      Volume: 47 Pages: 433-443

    • DOI

      10.1007/s00535-011-0500-0

    • NAID

      10030650144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390234, KAKENHI-PROJECT-24590996
  • [Journal Article] Supression of autophagy sensitizes Kupffer cells to endotoxin.2012

    • Author(s)
      Fukada H, Yamashina S, Izumi K, Komatsu M, Tanaka K, Ikejima K, Watanabe S.
    • Journal Title

      Hepatol. Res.

      Volume: 42 Pages: 1112-1118

    • DOI

      10.1111/j.1872-034x.2012.01024.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Journal Article] Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steaatohepatitis is regulated by leptin-mediated signaling.2012

    • Author(s)
      Imajo K, Fujita K, Yoneda M, Nozaki Y, Ogawa Y, Shinohara Y, Kato S, Mawatari H, Shibata W, Kitani H, Ikejima K, Kirikoshi H, Nakajima N, Saito S, Maeyama S, Watanabe S, Wada K, Nakajima A
    • Journal Title

      Cell Metabolism

      Volume: 16(1) Pages: 44-54

    • DOI

      10.1016/j.cmet.2012.05.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659402, KAKENHI-PROJECT-24590996, KAKENHI-PROJECT-24659823
  • [Journal Article] Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells2011

    • Author(s)
      Wang X, Ikejima K, Kon K, Arai K, Aoyama T, Okumura K, Abe W, Sato N, Watanabe S
    • Journal Title

      J Hepatol

      Volume: 55(2) Pages: 379-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Loss of autophagy promotes murine acetaminophen hepatotoxicity2011

    • Author(s)
      Igusa Y, Yamashina S, Izumi K, Inami Y, Fukada H, Komatsu M, Tanaka K, Ikejima K
    • Journal Title

      Watanabe S J Gastroenterol

    • NAID

      10030650144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Journal Article] 特集II NASH/NAFLD発症のメカニズム肝NKT細胞による脂肪性肝炎発症制御メカニズム2011

    • Author(s)
      池嶋健一, 山形寿文, 石川幸子, 細谷聡子, 今一義, 渡辺純夫
    • Journal Title

      消化器内科

      Volume: 52(5) Pages: 543-547

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression2011

    • Author(s)
      Inami Y, Yamashina S, Izumi K, Ueno T, Tanida I, Ikejima K, Watanabe S
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412(4) Pages: 618-618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Journal Article] Hepatic steatosis inhibits autophagic proteolysis via impairment aut ophagosomal acidification and cathepsin expression2011

    • Author(s)
      Inami Y, Yamashina S, Izumi K, Ueno T Tanida I, Ikejima K, Watanabe S
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412 Pages: 618-625

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Izunai K, Ueno T Tanida I, Watanabe S.Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression2011

    • Author(s)
      Inami Y, Yamashina S, Ikejima K, et al.(7人中6番目)
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412 Pages: 618-625

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice2011

    • Author(s)
      Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
    • Journal Title

      J Hepatol

      Volume: 54(6) Pages: 1195-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集全身疾患としての非アルコール性脂肪性肝疾患(NAFLD) NAFLD/NASHの病態2011

    • Author(s)
      池嶋健一, 渡辺純夫
    • Journal Title

      診断と治療

      Volume: 99(9) Pages: 1498-1506

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Loss of autophagy promotes murine ace taminophen hepatotoxicity2011

    • Author(s)
      Igusa Y, Yamashina S, Izumi K, Inami Y, Fukada H, Komatsu M, Tanaka K, Ikejima K, Watanabe S
    • Journal Title

      J Gastroenterol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article]2010

    • Author(s)
      池嶋健一, 渡辺純夫
    • Journal Title

      第8章 肝疾患 10. 脂肪肝, 脂肪性肝炎. 医学スーパーラーニングシリーズ 消化器内科学(渡辺純夫編)(シュプリンガー・ジャパン)

      Pages: 254-258

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集「NASHの診断と治療」NAFLD・NASHの治療アプローチ-理論的背景とエビデンス-2010

    • Author(s)
      池嶋健一
    • Journal Title

      診療と新薬

      Volume: 47(2) Pages: 37-45

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Diabetic KK-Ay mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen2010

    • Author(s)
      Kon K, Ikejima K, Okumura K, Arai K, Aoyama T, Watanabe S
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy.2010

    • Author(s)
      Mizui T, Yamashina S, Ikejima K, et al., (12人中7番目)
    • Journal Title

      J Gastroenterol

      Volume: 45 Pages: 195-203

    • NAID

      10027214573

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集非アルコール性脂肪肝炎(NASH)-病態の解明と診断・治療法の確立NASH/NAFLDの治療法インスリン抵抗性改善薬2010

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Journal Title

      Current Therapy

      Volume: 28(12) Pages: 37-42

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Diabetic KK-A^y mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen.2010

    • Author(s)
      Kon K, Ikejima K, Okumura K, et al., (6人中2番目)
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集肝胆膵薬物治療学の進歩-この30年-肝臓分野: VII. NASH・AIH・PBCベザフィブラート2010

    • Author(s)
      池嶋健一
    • Journal Title

      肝胆膵

      Volume: 61(6) Pages: 1107-1111

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy2010

    • Author(s)
      Mizui T, Yamashina S, Tanida I, Takei Y, Ueno T, Sakamoto N, Ikejima K, Kitamura T, Enomoto N, Sakai T, Kominami E, Watanabe S
    • Journal Title

      J Gastroenterol

      Volume: 45(2) Pages: 195-203

    • NAID

      10027214573

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集NASH II.基礎的メカニズムの解明1. NASHモデル2010

    • Author(s)
      池嶋健一, 宮地隆史, 渡辺純夫
    • Journal Title

      The Lipid

      Volume: 21(3) Pages: 38-45

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 臨時増刊NASH/NAFLDのすべて成因から栄養療法までNASH/NAFLDと関連疾患Topics線維化の成立機構と診断法2010

    • Author(s)
      池嶋健一, 福原京子, 渡辺純夫
    • Journal Title

      臨床栄養

      Volume: 116(6) Pages: 665-670

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集 NASH II.基礎的メカニズムの解明1.NASHモデル2010

    • Author(s)
      池嶋健一, 宮地隆史, 渡辺純夫
    • Journal Title

      The Lipid

      Volume: 21 Pages: 38-45

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] III.消化器疾患7.肝硬変・肝不全.テーラーメイド治療のための治療薬の選択と使用法ガイドライン実地医家に必須の56疾患2010

    • Author(s)
      池嶋健一
    • Journal Title

      Medical Practice

      Volume: vol.27(臨時増刊号) Pages: 136-142

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Hepatic sinusoidal cells in health and disease : update from the 14th International Symposium2009

    • Author(s)
      Smedsrod B, Le Couteur D, Ikejima K, Jaeschke H, Kawada N, Naito M, Knolle P, Nagy L, Senoo H, Vidal-Vanaclocha F, Yamaguchi N
    • Journal Title

      Liver Int

      Volume: 29(4) Pages: 490-501

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集NASH NASHの治療22009

    • Author(s)
      池嶋健一, 渡辺純夫
    • Journal Title

      薬物療法.治療学

      Volume: 43(10) Pages: 69-74

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice2009

    • Author(s)
      Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S
    • Journal Title

      Hepatology

      Volume: 49(5) Pages: 1636-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] A Special Edition 4 NAFLD/NASHの発症機序2009

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Journal Title

      BIO Clinica

      Volume: 24(13) Pages: 30-34

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集肝病態生理研究のあゆみ16.肝星細胞活性化に対するPTENの抑制効果2009

    • Author(s)
      高島基樹, 池嶋健一, 今一義, 山科俊平, 鈴木聡子, 渡辺純夫
    • Journal Title

      薬理と治療(JPT)

      Volume: 37

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Role of mitochondria in liver pathophysiology2009

    • Author(s)
      Yamashina S, Sato N, Kon K, Ikejima K, Watanabe S
    • Journal Title

      Drug Discovery Today : Disease Mechanisms

      Volume: 6(1-4)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-A^y mice2009

    • Author(s)
      Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S.
    • Journal Title

      Hepatology. 49(5)

      Pages: 1636-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation2009

    • Author(s)
      Takashima M, Parsons CJ, Ikejima K, Watanabe S, White ES, Rippe RA
    • Journal Title

      J. Gastroenterol

      Volume: 44(8) Pages: 847-55

    • NAID

      10025176656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Synthetic triglyceride containing an arachidonic acid branch(8A8) prevents lipopolysaccharide-induced liver injury2009

    • Author(s)
      Piao N, Ikejima K, Kon K, Aoyama T, Osada T, Takei Y, Sato N, Watanabe S
    • Journal Title

      Life Sci

      Volume: 85(17-18) Pages: 617-24

    • NAID

      110007125463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation2009

    • Author(s)
      Takashima M, Parsons CJ, Ikejima K, Watanabe S, White ES, Rippe RA
    • Journal Title

      J.Gastroenterol. 44(8)

      Pages: 847-55

    • NAID

      10025176656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集肝疾患を生活習慣から考えるII.非アルコール性脂肪性肝障害の最近の動向2) NASH(1)病因、病態の新しい展開2009

    • Author(s)
      柳沼礼子, 池嶋健一, 渡辺純夫
    • Journal Title

      成人病と生活習慣病

      Volume: 39(4)

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] 特集肝病態生理研究のあゆみ17.肝細胞内脂肪的蓄積と肝細胞しにおける肝細胞内貯蔵鉄の役割2009

    • Author(s)
      今一義, 池嶋健一, 青山友則, 山形寿文, 渡辺純夫
    • Journal Title

      薬理と治療(JPT)

      Volume: 3

    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice2009

    • Author(s)
      Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S
    • Journal Title

      Hepatology 49(5)

      Pages: 1636-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Synthetic triglyceride containing an arachidonic acid branch(8A8)prevents lipopolysaccharide-induced liver injury2009

    • Author(s)
      Piao N, Ikejima K, Kon K, Aoyama T, Osada T, Takei Y, Sato N, Watanabe S.
    • Journal Title

      Life Sci. 85(17-18)

      Pages: 617-24

    • NAID

      110007125463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Journal Article] Death receptor 5 mediatedapoptosis contributes to cholestatic liver disease2008

    • Author(s)
      Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K, Aoyama T, Frese S, Ikeda H, Haynes N, Cretney E, Yagita H, Sueyoshi N, SatoN, Nakanuma Y, Smyth M, Okumura K
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105(31)

      Pages: 10895-10900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集ウイルス性慢性肝炎 : 診断と治療の進歩トピックスIV. C型慢性肝炎の抗ウイルス療法2. C型慢性肝炎の進展と治療抵抗性2)宿主側因子の関与2008

    • Author(s)
      池嶋健一, 柳沼礼子, 渡辺純夫
    • Journal Title

      日本内科学会雑誌 97(1)

      Pages: 69-74

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集肝疾患と糖代謝, 脂質代謝VI. 糖代謝および脂質代謝異常と肝臓4. 脂肪肝と肝切除2008

    • Author(s)
      池嶋健一, 青山友則, 渡辺純夫
    • Journal Title

      肝胆膵 56(1)

      Pages: 119-125

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 連載第18回No.35シグナル伝達を理解するために必要な知識Eカドヘリンによるシグナル伝達2008

    • Author(s)
      高島基樹, 池嶋健一, 渡辺純夫
    • Journal Title

      分子消化器病 5(2)

      Pages: 68-71

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] KK-Ayマウスにおける肝再生不全-Pioglitazoneによる改善効果の検討-.2008

    • Author(s)
      青山友則, 池嶋健一, 今一義, 山形寿文, 柳沼礼子, 山科俊平, 渡辺純夫.
    • Journal Title

      薬理と治療(JPT) 36suppl

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集II鉄代謝と消化器疾患酸化ストレスに伴う肝細胞障害における鉄イオンの細胞内動態と細胞死への影響2008

    • Author(s)
      内山明, 池嶋健一, 今一義, 渡辺純夫
    • Journal Title

      消化器科 46(2)

      Pages: 229-233

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集C型肝炎のすべて2009合併症を有する患者のHCV治療肝脂肪化合併HCVとInterferon治療2008

    • Author(s)
      柳沼礼子, 池嶋健一, 渡辺純夫
    • Journal Title

      肝胆膵 57(5)

      Pages: 949-957

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 1. ペグインターフェロン・リバビリン併用療法の治療成績2008

    • Author(s)
      渡辺純夫, 鈴木聡子, 池嶋健一
    • Journal Title

      Progress in Medicine 28(11)

      Pages: 2625-2629

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Liver diseases and metabolic syndrome2008

    • Author(s)
      Watanabe S, Yaginuma R, Ikejima K, Miyazaki A
    • Journal Title

      J. Gastroenterol 43

      Pages: 509-518

    • NAID

      10021937059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集NASH/NAFLDの臨床および研究の進歩NASH/NAFLDの成因と病態2008

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Journal Title

      Medical Science Digest 36(7)

      Pages: 27-30

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集肝病態生理研究のあゆみ12. 酸化ストレスに伴う肝細胞障害における鉄イオンの細胞内動態と細胞死への影響2008

    • Author(s)
      内山明, 池嶋健一, 今一義, 渡辺純夫
    • Journal Title

      薬理と治療(JPT) 36suppl

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 第42回日本成人病(生活習慣病)学会 : 「教育講演」より 脂肪肝から肝癌へ-NASHの病態を考える2008

    • Author(s)
      柳沼礼子, 池嶋健一, 渡辺純夫
    • Journal Title

      成人病と生活習慣病 38(5)

      Pages: 539-545

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集肝病態生理研究のあゆみ11. Sphingosine1-phosphate(S1P)の肝類洞内皮細胞に及ぼす影響2008

    • Author(s)
      北村庸雄, 鄭冬梅, 池嶋健一, 榎本信行, 山科俊平, 今一義, 鈴木聡子, 竹井謙之, 佐藤信紘, 渡辺純夫
    • Journal Title

      薬理と治療(JPT) 36suppl

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集肝病態生理研究のあゆみ19. KK-Ayマウスにおける肝再生不全-Pioglitazoneによる改善効果の検討-2008

    • Author(s)
      青山友則, 池嶋健一, 今一義, 山形寿文, 柳沼礼子, 山科俊平, 渡辺純夫
    • Journal Title

      薬理と治療(JPT) 36suppl

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集肝病態生理研究のあゆみ27. NAFLD患者に対する低用量ピオグリタゾン投与の有用性について2008

    • Author(s)
      柳沼礼子, 池嶋健一, 福原京子, 青山友則, 今一義, 水井智和, 山科俊平, 鈴木聡子, 渡辺純夫
    • Journal Title

      薬理と治療(JPT) 36suppl

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Translocation of Iron from Lysosomes into Mitochondria is a Key Event During Oxidative Stress-Induced Hepatocellular Injury2008

    • Author(s)
      Uchiyama A, Kim JS, Kon K, Jaeschke H, Ikejima K, Watanabe S, Lemasters JJ
    • Journal Title

      Hepatology 48(5)

      Pages: 1644-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Low molecular weight heparin prevents hepatic fibrogenesis caused carbon tetrachloride in the rat.2007

    • Author(s)
      Abe W, Ikejima K, Lang T, Okumura K, Enomoto N, Kitamura T, Takei Y, Sato N.
    • Journal Title

      J. Hepatol. 46

      Pages: 286-294

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] 特集 : NASH-最新の知見4. NASHの成因と病態(2)NASHとメタボリックシンドローム2007

    • Author(s)
      池嶋健一, 今一義, 青山友則, 山科俊平, 鈴木聡子, 渡辺純夫
    • Journal Title

      臨床消化器内科 22(11)

      Pages: 1451-1458

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] メタボリックシンドロームにおける薬物性肝障害の増悪-KKAyマウスを用いた検討-2007

    • Author(s)
      今一義, 池嶋健一, 青山友則, 竹井謙之, 渡辺純夫
    • Journal Title

      薬理と治療 35suppl

      Pages: 253-256

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Role of adipocytokines in hepatic fibrogenesis2007

    • Author(s)
      Ikejima K, Okumura K, Kon K, Takei Y, Sato N.
    • Journal Title

      J.Gastroenterol.Hepatol 22

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity2007

    • Author(s)
      Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N
    • Journal Title

      J. Gastroenterol. Hepatol 22(3)

      Pages: 423-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Role of adipocytokines in hepatic fibrogenesis.2007

    • Author(s)
      Ikejima K, Okumura K, Kon K. Takei Y, Sato N.
    • Journal Title

      J. Gastroen terol. Hepatol. 22(Suppll)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] 特集プライマリ・ケア医のためのNAFLDの診かた-非アルコール性脂肪性肝疾患への対応と最新知見-2007

    • Author(s)
      池嶋健一, 今一義, 渡辺純夫
    • Journal Title

      各論 : NAFLDの治療高血圧合併例. 治療 89

      Pages: 1691-1695

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Low molecular weight heparin prevents hepatic fibrogenesis caused by carbon tetrachloride in the rat.2007

    • Author(s)
      Abe W, Ikejima K, Lang T, Okumura K, Enomoto N, Kitamura T, Takei Y, Sato N.
    • Journal Title

      J.Hepatol. 46

      Pages: 286-294

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Role of adipocytokines in hepatic fibrogenesis2007

    • Author(s)
      Ikejima K, Okumura K, Kon K, Takei Y, Sato N
    • Journal Title

      J. Gastroenterol. Hepatol 22(Suppl1)

      Pages: 87-92

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity2007

    • Author(s)
      Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
    • Journal Title

      J.Gastroenterol.Hepatol. 22(3)

      Pages: 423-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] 特集子供を蝕む大人の病気各論脂肪肝/NASH/アルコール性肝障害2007

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Journal Title

      小児科 48(5)

      Pages: 563-568

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Orthotopic hepatocellular carcinoma model with a com rolle and reproducible tumorigenicity.2007

    • Author(s)
      Oktubo H, Takei Y. Serizawa N, Enomoto N. Ikejima K. Sato N.
    • Journal Title

      J. Gastroenterol. Hepatol. 22(3)

      Pages: 423-428

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity2007

    • Author(s)
      Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
    • Journal Title

      J.Gastroenterol.Hepatol 22(3)

      Pages: 423-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity.2007

    • Author(s)
      Okubo H. Takei Y. Serizawa N. Enomoto N. Ikejima K. Sato N.
    • Journal Title

      J. Gastroenterol. Hepatol 22(3)

      Pages: 423-428

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Journal Article] Role of apoptosis in acetaminophen hepatotoxicity2007

    • Author(s)
      Kon K, Ikejima K, Okumura K, Aoyama T, Arai K, Takei Y, Lemasters JJ, Sato N
    • Journal Title

      J. Gastroenterol. Hepatol 22(Suppl1)

      Pages: 49-52

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] 特集 非アルコール性脂肪性肝炎(NASH) -疾患概念からマネージメントまで- 肝発癌 発癌機序.2006

    • Author(s)
      池嶋健一, 青山友則.
    • Journal Title

      肝胆膵 53(3)

      Pages: 401-408

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Orthotopic Hepatocellular Carcinoma Model with a Controlled and Reproducible Tumorigenicity.2006

    • Author(s)
      Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
    • Journal Title

      Journal of Gastroenterology and Hepatology (in press)

    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] 非アルコール性脂肪性肝炎におけるレプチンの役割.2006

    • Author(s)
      池嶋健一, 佐藤信紘.
    • Journal Title

      最新医学 61(5)

      Pages: 1033-1039

    • NAID

      40007262381

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Genetic Manipulation of Sinusoidal Endothelial Cells2006

    • Author(s)
      Yoshiyuki Takei, Atsushi Maruyama, Kenichi Ikejima, et al.
    • Journal Title

      Journal of Gastroenterology and Hepatology (in press)

    • NAID

      110004011831

    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] 特集 非B非C型肝炎 4.NASHと非B非C型肝炎 (2)NASHにおける病態進展の危険因子.2006

    • Author(s)
      池嶋健一, 奥村京子, 今一義, 青山友則, 竹井謙之, 佐藤信紘.
    • Journal Title

      臨床消火器内科 21(12)

      Pages: 1621-1628

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] 特集 生活習慣と肝臓病:診断と治療の進歩 トピックスV.肥満をめぐる進歩 2.レブチンの概念2006

    • Author(s)
      池嶋健一, 佐藤信紘.
    • Journal Title

      日本内科学会雑誌 95(1)

      Pages: 94-99

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] 特集 生活習慣と肝臓病:診断と治療の進歩 トピックスV.肥満をめぐる進歩 2.レプチンの概念2006

    • Author(s)
      池嶋健一, 佐藤信紘
    • Journal Title

      日本内科学会雑誌 95(1)

      Pages: 94-99

    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Hepatic steatosis is a predictor of poor response to interferon α-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.2006

    • Author(s)
      Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, Sato N.
    • Journal Title

      Hepatol Res. 35(1)

      Pages: 19-25

    • NAID

      10020329566

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK・A^y mice.2006

    • Author(s)
      Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
    • Journal Title

      Hepatol. Res. 36

      Pages: 217-228

    • NAID

      10018640284

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-Ay mice.2006

    • Author(s)
      Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
    • Journal Title

      Hepatol.Res. 36

      Pages: 217-228

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis : role of intracellular calcium and nitric oxide.2006

    • Author(s)
      Zheng DM, Kitamura T, Ikejima K, Enomoto N, Yamashina S, Suzuki S, Takei Y, Sato N.
    • Journal Title

      Hepatology 44

      Pages: 1278-1287

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization.2005

    • Author(s)
      Enomoto N, Takei Y, Yamashina S, Ikejima K, Kitamura T, Sato N.
    • Journal Title

      Alcohol Clin.Exp.Res. 29(12 Suppl)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Roles of Kupffer cells in alcoholic liver disease.2005

    • Author(s)
      Takei Y, Enomoto N, Ikejima K, Yamashina S, Kitamura T, Sato N
    • Journal Title

      In Comprehensive Handbook of Alcohol Related Pathology (Academic Press, London) (Preedy VR and Watson RR, Eds)

      Pages: 749-759

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005

    • Author(s)
      Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
    • Journal Title

      Hepatol.Res. 33(2)

      Pages: 151-154

    • NAID

      10016809329

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Hepatic steatosis is a predictor of poor response to interferon α-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.2005

    • Author(s)
      Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, Sato N.
    • Journal Title

      Hepatol.Res.

    • NAID

      10020329566

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Smad and p38 MAPK signaling pathways independently regulate α1(I) collagen gene expression in unstimulated and TGF-β stimulated hepatic stellate cells.2005

    • Author(s)
      Tsukada S, Westwick JK, Ikejima K, Sato N, Rippe RA.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 10055-10064

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] NASHの発症・進展におけるレプチンの関与.2005

    • Author(s)
      池嶋健一, 佐藤信紘.
    • Journal Title

      消化器科 40

      Pages: 79-83

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005

    • Author(s)
      Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
    • Journal Title

      Hepatol Res. 33

      Pages: 151-154

    • NAID

      10016809329

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] メタボリックシンドロームと肝臓-特にレプチンの役割.2005

    • Author(s)
      池嶋健一, 佐藤信紘
    • Journal Title

      日本消化器病学会雑誌 102(11)

      Pages: 1392-1397

    • NAID

      10016947860

    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] メタボリックシンドロームと肝臓-特にレプチンの役割.2005

    • Author(s)
      池嶋健一, 佐藤信紘.
    • Journal Title

      日本消化器病学会雑誌 102(11)

      Pages: 1392-1397

    • NAID

      10016947860

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Glycine as a therapeutic immuno-nutrient for alcoholic liver disease.2005

    • Author(s)
      Yamashina S, Ikejima K, Enomoto N, Takei Y, Sato N.
    • Journal Title

      Alcohol Clin Exp Res. 29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress.2005

    • Author(s)
      Yamashina S, Takei Y, Ikejima K, Enomoto N, Kitamura T, Sato N.
    • Journal Title

      Alcohol Clin Exp Res. 29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress.2005

    • Author(s)
      Yamashina S, Takei Y, Ikejima K, Enomoto N, Kitamura T, Sato N.
    • Journal Title

      Alcohol Clin.Exp.Res. 29(12 Suppl)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Role of leptin in pathogenesis of NASH.2005

    • Author(s)
      Ikejima K, Lang T, Yamashina S, Enomoto N, Takei Y, Sato N.
    • Journal Title

      In NASH and Nutritional Therapy. (Tokyo : Springer-Verlag) (Okita K, Ed.)

      Pages: 44-49

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Smad and p38 MAPK signaling pathways independently regulate α1(I) collagen gene expression in unstimulated and TGF-β stimulated hepatic stellate cells.2005

    • Author(s)
      Tsukada S, Westwick JK, Ikejima K, Sato N, Rippe RA.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 10055-10064

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005

    • Author(s)
      Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
    • Journal Title

      Hepatol.Res. 33(2)

      Pages: 151-154

    • NAID

      10016809329

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Targeted gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004

    • Author(s)
      Takei Y, Maruyama A, Ferdous A, Nishimura Y, Kawano S., Ikejima K, Okumura S., Asayama S, Nogawa M, Hashimoto M, Makino Y, Kinoshita M, Watanabe S, Akaike T, Lemasters JJ, Sato N.
    • Journal Title

      FASEB J. (10.1096/fj.03-0494fje, published on line February 20, 2004) 18

      Pages: 699-701

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 323

      Pages: 1091-1095

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] NASHの病態2004

    • Author(s)
      竹井謙之, 池嶋健一, 佐藤信紘
    • Journal Title

      日本消火器病学会誌 101

      Pages: 1194-1203

    • NAID

      10014292099

    • Data Source
      KAKENHI-PROJECT-14657136
  • [Journal Article] Genetic manipulation of liver sinusoidal endothelial cells.2004

    • Author(s)
      Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
    • Journal Title

      In Organ Microcirculation : A gateway to diagnostic and therapeutic interventions. (Springer-Verlag, Tokyo ) (Ishii H, Ed.)

      Pages: 129-134

    • NAID

      10012736253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Senescence marker protein-30 (SMP3O) regulates Akt activity and contributes to cell survival in Hep G2 cells.2004

    • Author(s)
      Matsuyama S, Kitamura T, Zheng D, Fujita T, Ishigami A, Handa S, Maruyama N, Enomoto N, Ikejima K, Takei Y, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 321

      Pages: 386-390

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] 肝炎の発癌-サイトカインの役割2004

    • Author(s)
      池嶋健一, 佐藤信紘
    • Journal Title

      Surgery Frontier 11

      Pages: 44-48

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] アルコール性肝障害におけるレプチンの役割2004

    • Author(s)
      池嶋健一, 佐藤信紘
    • Journal Title

      消化器科 38

      Pages: 575-579

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 323

      Pages: 1091-1095

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 323

      Pages: 1091-1095

    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Yakei Y, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 323

      Pages: 1091-1095

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004

    • Author(s)
      Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Comparative Hepatology3 (Suppl I) S12

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004

    • Author(s)
      Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Comparative Hepatology 3(Suppl I)

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice.2004

    • Author(s)
      Ishizaki-Koizumi S, Sonaka I, Takei Y, Ikejima K, Sato N.
    • Journal Title

      Biochem Biophys Res Commun. 322

      Pages: 514-519

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lant T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 323

      Pages: 1091-1095

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut-derived endotoxin.2004

    • Author(s)
      Enomoto N, Takei Y, Yamashina S, Fukuda T, Suzuki S, Ikejima K, Kitamnra T, Sato N.
    • Journal Title

      J.Gastroenterol. 39

      Pages: 1175-1181

    • NAID

      10014091735

    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004

    • Author(s)
      Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Comparative Hepatology 3(Suppl I)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-α in isolated rat Kupffer cells and exerts hepatoprotective effects in mice.2004

    • Author(s)
      Ishizaki-Koizumi S, Sonaka I, Takei Y, Ikejima K, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun 322

      Pages: 514-519

    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] NASHの病態2004

    • Author(s)
      竹井謙之, 池嶋健一, 砂防信紘
    • Journal Title

      日本消化器病学会雑誌 101

      Pages: 1194-1203

    • NAID

      10014292099

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Effect of PPAR-γ agonist on transdifferentiation of hepatic stellate cells.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K. et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 323

      Pages: 1091-1095

    • Data Source
      KAKENHI-PROJECT-14657136
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Yakei Y, Sato N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 323

      Pages: 1091-1095

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004

    • Author(s)
      Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Comparative Hepatology 3(SupplI)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] Thalidomide prevents alcoholic liver injury in rats through inhibition of Kupffer cell sensitization.2004

    • Author(s)
      Enomoto N, Takei Y, Hirose M, Ikejima K, Kitamura T, Sato N.
    • Journal Title

      Comparative Hepatology 3(Suppl I)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] NASHの病因:酸化ストレスとサイトカインの関与2004

    • Author(s)
      竹井謙之, 池嶋健一, 佐藤信紘
    • Journal Title

      肝臓 45

      Pages: 77-81

    • NAID

      10012915441

    • Data Source
      KAKENHI-PROJECT-16590633
  • [Journal Article] Targeted Gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004

    • Author(s)
      Takei Y, Maruyama A, Ferdous A, Nishimura Y, Kawano S, Ikejima K, Okumura S, Asayama S, Nogawa M, Hashimoto M, Makino Y, Kinoshita M, Watanabe S, Akaike T, Lemasters JJ, Sato N.
    • Journal Title

      FASEBJ. 18

      Pages: 699-701

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390235
  • [Journal Article] 特集肥満へのアプローチ肥満症・メタボリックシンドロームの治療・管理(合併症の診断と治療)非アルコール性脂肪性肝炎(NASH)

    • Author(s)
      池嶋健一, 渡辺純夫
    • Journal Title

      治療 90(5)

      Pages: 1727-1732

    • Data Source
      KAKENHI-PROJECT-19590791
  • [Journal Article] Orthotopic Hepatocellular Carcinoma Model with a Controlled and Reproducible Tumorigenicity.

    • Author(s)
      Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
    • Journal Title

      J Gastro Heaptol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Journal Article] Genetic Manipulation of Liver Sinusoidal Endothelial Cells.

    • Author(s)
      Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
    • Journal Title

      J Gastroenterol Hepatol (in press)

    • NAID

      10012736253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590690
  • [Presentation] アミノ酸グリシンによる脂肪肝炎の改善効果―肝特異的PTENノックアウトマウスを用いた検討-2021

    • Author(s)
      今一義、新井久美子、内山明、深田浩大、中寺英介、山科俊平、池嶋健一
    • Organizer
      第58回 日本消化器免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K08315
  • [Presentation] 肝細胞特異的PTENノックアウトマウスにおけるグリシンの脂肪肝炎・肝がん抑制効果2021

    • Author(s)
      今一義,山科俊平,池嶋健一
    • Organizer
      Japan Digestive Disease Week 2021
    • Data Source
      KAKENHI-PROJECT-20K08315
  • [Presentation] 肝特異的PTEN欠損脂肪肝炎モデルマウスにおける アミノ酸グリシンの効果2021

    • Author(s)
      今一義,山科俊平,池嶋健一
    • Organizer
      第107回 日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-20K08315
  • [Presentation] KK-Ayマウスアルコール性肝炎モデルにおけるリファキシミンの小腸細菌叢再構築を介した肝障害抑制効果.2019

    • Author(s)
      北川隆太、今一義、池嶋健一.
    • Organizer
      JDDW2019 (第61回日本消化器病学会大会), ンポジウム7-3
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] The role of intestinal microbiota in alcoholic liver disease.2019

    • Author(s)
      Kitagawa R, Kon K, Ikejima K.
    • Organizer
      the 17th Congress of the European Society for Biomedical Research on Alcoholism (ESBRA).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] Endoplasmic reticulum stress and oxidative stress in alcoholic liver injury comorbid metabolic syndrome.2019

    • Author(s)
      Kon K, Suzuki M, Ikejima K.
    • Organizer
      the 17th Congress of the European Society for Biomedical Research on Alcoholism (ESBRA).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] Aging causes the exacerbation of dietary steatohepatitis accompanied by muscle weakness in mice.2019

    • Author(s)
      Ishizuka K, Kon K, Arai K, Uchiyama A, Yamashina S, Ikejima K.
    • Organizer
      Digestive Disease Week2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] アルコール性肝炎発症における小胞体-ミトコンドリアストレスの関与.2019

    • Author(s)
      今一義、内山明、池嶋健一.
    • Organizer
      第19回抗加齢医学会総会.
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] 高脂質負荷による脂肪性肝炎と脂質組成変化における加齢の影響.2019

    • Author(s)
      石塚敬、今一義、池嶋健一.
    • Organizer
      第105回日本消化器病学会総会.シンポジウム 8
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] 加齢における脂肪肝炎の増悪と骨格筋萎縮の病態メカニズム2019

    • Author(s)
      石塚敬, 今一義, 内山明, 深田浩大, 山科俊平, 池嶋健一.
    • Organizer
      JDDW2019
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] Age-related enhancement of cellular stresses and lipotoxicity exacerbates dietary steatohepatitis in mice.2019

    • Author(s)
      Ishizuka K, Kon K, Lee HC, Arai K, Uchiyama A, Fukuo H, Yamashina S, Yokomizo T, Ikejima K.
    • Organizer
      American Association for the Study of Liver Disease (AASLD) Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] 脂肪性肝炎の肝内脂質組成変化における加齢の影響2019

    • Author(s)
      石塚 敬、今 一義、池嶋健一
    • Organizer
      第105回日本消化器病学会総会 シンポジウム8
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] 加齢に伴う脂質代謝変化による食事誘発性脂肪性肝炎の増悪機序.2019

    • Author(s)
      石塚敬、今一義、池嶋健一.
    • Organizer
      第55回日本肝臓学会総会.パネルディスカッション 7-6
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] アルコール性肝障害マウスにおける小腸内細菌叢の変化と肝障害に与える影響.2019

    • Author(s)
      今一義、北川隆太、深田浩大、内山明、山科俊平、池嶋健一.
    • Organizer
      第56回日本消化器免疫学会総会.シンポジウム1
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] AGING CAUSES THE EXACERBATION OF DIETARY STEATOHEPATITIS ACCOMPANIED BY MUSCLE WEAKNESS IN MICE2019

    • Author(s)
      Kei Ishizuka, Kazuyoshi Kon, Kumiko Arai, Akira Uchiyama, Shunhei Yamashina, and Kenichi Ikejima
    • Organizer
      DDW 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] リファキシミンによる小腸細菌叢の変化を介したアルコール性肝障害抑制効果:肥満KK-Ay マウスを用いた検討.2019

    • Author(s)
      北川隆太、今一義、池嶋健一.
    • Organizer
      第55回日本肝臓学会総会.ワークショップ8
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] リファキシミンを用いた腸内細菌叢の制御によるメタボリック+アルコール性脂肪肝炎の抑制効果.2019

    • Author(s)
      北川隆太、今一義、内山明、山科俊平、池嶋健一.
    • Organizer
      アルコール・アディクション医学会総会
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] 加齢による非アルコール性脂肪肝炎の増悪機序―高齢マウスを用いた検討―2018

    • Author(s)
      石塚敬、今一義、青山友則、内山明、山科俊平、池嶋健一、渡辺純夫
    • Organizer
      第104回 日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] 加齢による非アルコール性脂肪肝炎の増悪機序―高脂肪負荷高齢マウスを用いた検討―2018

    • Author(s)
      石塚敬、今一義、青山友則、内山明、山科俊平、池嶋健一
    • Organizer
      第22回日本肝臓学会大会
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] Aging-dependent alterations in hepatic fatty acid metabolism exacerbate murine dietary steatohepatitis through enhancing lipotoxicity2018

    • Author(s)
      Kei Ishizuka, Kazuyoshi Kon, Kumiko Arai, Akira Uchiyama, Tomonori Aoyama, Shunhei Yamashina, and Kenichi Ikejima
    • Organizer
      AASLD 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] L-carnitine changes hepatic lipid composition and prevents lipotoxicity in hign-fat diet-fed KK-Ay mice.2017

    • Author(s)
      Kon K, Ikejima K, Uchiyama A, Arai K, Aoyama T, Yamashina S, Watanabe S.
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] The formation of P62-positive inclusion body is associated with macrophage polarization in non-alcohoic fatty liver disease.2017

    • Author(s)
      Fukushima H, Yamashina S, Arakawa A, Taniguchi G, Aoyama T, Uchiyama A, Kon K, Ikejima K, Watanabe S.
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Female hormone enhances hepatic innate and autoimmune responses against double-stranded RNA.2017

    • Author(s)
      Uchiyama A, Ikejima K, Someya S, Arai K, Aoyama T, Kon K, Yamashina S, Watanabe S.
    • Organizer
      the Liver Meeting 2017 (AASLD)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Glycine minimizes murine autoimmune cholangitisand pancreatitis caused by double-stranded RNA through modulation of innate immune response.2017

    • Author(s)
      Uchiyama A, Ikejima K, Kon K, Arai K, Fukuhara K, Aoyama T, Yamashina S, Watanabe S 演題名 GLYCINE MINIMIZES MURINE AUTOIMMUNE CHOLANGITIS AND PANCREATITIS CAUSED BY DOUBLE-STRANDED RNA THROUGH MODULATION OF INNATE IMMUNE RESPONSES 学会名
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Aging exacerbates high-fat diet-induced steatohepatitis through blunting of lipid metabolic response in mice2017

    • Author(s)
      Ishizuka K, Kon K, Ikejima K, Suzuki M, Arai K, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
    • Organizer
      AASLD annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09440
  • [Presentation] Aging exacerbates high-fat diet-induced steatohepatitis through blunting of lipid metabolic response in mice.2017

    • Author(s)
      Ishizuka K, Kon K, Ikejima K, Suzuki M, Arai K, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
    • Organizer
      the Liver Meeting 2017 (AASLD)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] 自己免疫性胆管病変マウスモデルにおける性差の解析2016

    • Author(s)
      染谷秀忍,池嶋健一,内山明,鈴木麻衣子,青山友則,今一義,山科俊平,渡辺純夫
    • Organizer
      JDDW2016
    • Place of Presentation
      神戸
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Real-world efficacy of antiviral treatment using a combination of daclatasvir and asnaprevir in Japanese patients of chronic hepatitis C2016

    • Author(s)
      Ikejima K, Fukuhara K, Aoyama T, Uchiyama A, Kon K, Yamashina S, Watanabe S
    • Organizer
      HCV2016
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2016-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] NAFLD・NASHの病態形成と自然免疫2016

    • Author(s)
      池嶋健一
    • Organizer
      第53回日本消化器免疫学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2016-07-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Metabolic disease and NASH2016

    • Author(s)
      Ikejima K, Kon K, Yamashina S, Watanabe S
    • Organizer
      25th Conference of the Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-02-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] 非アルコール性脂肪肝炎(NASH)の病態形成におけるリピドラフトの役割2016

    • Author(s)
      内山 明、池嶋 健一、渡辺 純夫
    • Organizer
      第52回日本肝臓学会総会
    • Place of Presentation
      幕張
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-15K09022
  • [Presentation] Gender-specific development of experimental autoimmune cholangitis induced by double-stranded RNA2016

    • Author(s)
      Someya S, Ikejima K, Uchiyama A, Arai K, Kon K, Aoyama T, Yamasina S, Watanabe S
    • Organizer
      The Liver Meeting 2016 (AASLD)
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Efficacy of denosumab on progression of osteoporosis in autoimmune liver diseases2016

    • Author(s)
      Ikejima K, Yaginuma R, Kon K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S
    • Organizer
      The Liver Meeting 2016 (AASLD)
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Immuno-nutritional approach for impaired glucose tolerance in metabolic steatohepatitis through modulation of Kupffer cell function2015

    • Author(s)
      Ikejima K, Kon K, Watanabe S
    • Organizer
      第23回日本消化器関連学会週間(JDDW)
    • Place of Presentation
      Tokyo
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Steatohepatitis syndromeの共通病態基盤としてのKupffer細胞極性変化と免疫栄養的制御2015

    • Author(s)
      池嶋健一,今一義,渡辺純夫
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2015-05-22
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Contribution of regulatory T cells in pathogenesis of nonalcoholic steatohepatitis in mice2015

    • Author(s)
      Ikejima K, Yokokawa J, Arai K, Uchiyama A, Kon K, Yamashina S, Watanabe S
    • Organizer
      18th International Symposium on the Cells of Hepatic Sinusoid
    • Place of Presentation
      Asilomar, CA, USA
    • Year and Date
      2015-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] Dietary glycine improves impaired glucose tolerance by modulating polarization of Kupffer cells in diabetic KK-Ay mice.2015

    • Author(s)
      Ikejima K, Arai K, Kon K, Uchiyama A, Yamashina S, Watanabe S
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2015-05-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09023
  • [Presentation] L-carnitine improves high-fat diet-induced steatohepatitis through insulin sensitization and regulation of lipid metabolism2014

    • Author(s)
      Kon K, Ikejima K, Kusama H, Morinaga M, Arai K, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
    • Organizer
      米国肝臓病学会(AASLD)
    • Place of Presentation
      米国 ボストン
    • Year and Date
      2014-11-09
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] メタボリックシンドロームモデルKK-Ayマウスにおけるアミノ酸による免疫調節2014

    • Author(s)
      池嶋健一,高嶋志在,渡辺純夫
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-24
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] The chemical chaperon 4-phenylbutyrate prevents epigenetic alterations and carcinogenesis in NASH-HCC model mice.2014

    • Author(s)
      Kazuyoshi Kon, Kenichi Ikejima, Akira Uchiyama, Tomonori Aoyama, Kumiko Arai, Maki Morinaga, Shunhei Yamashina and Sumio Watanabe
    • Organizer
      49th annual meeting of EASL the international liver congress.
    • Place of Presentation
      London
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] 脂肪性肝炎の病態形成における小胞体ストレスの役割2014

    • Author(s)
      今一義、池嶋健一、渡辺純夫
    • Organizer
      平成26年度アルコール・薬物依存関連学会合同学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-10-04
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] Dietary supplementation of glycine ameliorates diabetic steatohepatitis in KK-Ay mice through immune-metabolic regulation2014

    • Author(s)
      Ikejima K, Takashima S, Arai K, Kon K, Yamashina S, Watanabe S
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      Chicago
    • Year and Date
      2014-05-03
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] SUPPRESSION OF ENDOPLASMIC RETICULUM STRESS BY CHEMICAL CHAPERON INHIBITS CARCINOGENESIS IN STEATOHEPATITIS-RELATED HCC MODEL MICE2014

    • Author(s)
      Kon K, Ikejima K, Arai K, Morinaga M, Kusama H, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
    • Organizer
      ISBRA 2014 World Congress
    • Place of Presentation
      米国 ベルビュー
    • Year and Date
      2014-06-23
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] ストレプトゾトシン/高脂肪食による脂肪性肝炎由来肝発癌モデルの解析と化学シャペロンによる効果の検討2014

    • Author(s)
      今一義、池嶋健一、内山明、山科俊平、渡辺純夫
    • Organizer
      第50回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-05-29
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] Ursolic acid ameliorates murine cholangitis induced by double-stranded RNA2014

    • Author(s)
      Ikejima K, Arai K, Uchiyama A, Kon K, Yamashina S, Watanabe S.
    • Organizer
      European Association for the Study of the Liver
    • Place of Presentation
      London
    • Year and Date
      2014-04-11
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] Glycine prevents maturity-onset obesity and metabolic steatohepatitis in diabetic KK-Ay mice through modulation of hepatic innate immunity2013

    • Author(s)
      Ikejima K, Takashima S, Arai K, Kon K, Yamashina S, Watanabe S
    • Organizer
      Digestive Diesase Week
    • Place of Presentation
      Orlando, FL, USA
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] The effect of chemical chaperon on progression of steatohepatitis in a mouse model of steatohepatitisrelated HCC.2013

    • Author(s)
      今一義.池嶋健一.森永真紀.内山明.青山友則.山科俊平.渡辺純夫.
    • Organizer
      Japan Liver Cell Week
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] The expression of autophagy-related proteins in non-B non-C hepatocellular carcinogenesis.2013

    • Author(s)
      Kon K.Ikejima K.Uchiyama A.Yamashina S.Kawasaki S.Watanabe S.
    • Organizer
      Digestive Disease Week2013(DDW2013)
    • Place of Presentation
      Orlando
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] Hepatic regulatory T Cells contribute to the development of dietary steatohepatitis in mice.2013

    • Author(s)
      Yokokawa J, Ikejima K, Arai K, Kon K, Yamashina S, Watanabe S
    • Organizer
      American Association for the Study of Liver Diseases
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] Ursolic acid minimizes cholestatic liver injury in common bile duct-ligated rats2013

    • Author(s)
      Ikejima K, Arai K, Kon K, Yamashina S, Watanabe S
    • Organizer
      European Association for the Study of the Liver
    • Place of Presentation
      Amsterdam
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] 化学シャペロンによる脂肪性肝炎の病態抑制効果-脂肪性肝炎由来肝癌モデルマウスを用いた検討-.2013

    • Author(s)
      今一義.池嶋健一.内山明.山科俊平.渡辺純夫.
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] 非アルコール性脂肪性肝疾患患者におけるオートファジー機能障害とカテプシン発現異常2013

    • Author(s)
      福生有華,山科俊平,泉光輔,園上浩司,荒川敦,青山友則,内山明,今一義,鈴木聡子,池嶋健一,渡辺純夫
    • Organizer
      肝臓(0451-4203)54巻Suppl.1 PageA146
    • Data Source
      KAKENHI-PROJECT-23590989
  • [Presentation] Long term efficacy and safety of low-dose pioglitazone treatment for nonalcoholic fatty liver disease with insulin resistance2013

    • Author(s)
      Ikejima K, Fukuhara K, Yaginuma R, Kon K, Yamashina S, Suzuki S, Watanabe S
    • Organizer
      Asian Pacific Association for the Study of the Liver (APASL) Liver Week 2013
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] 非B非C肝癌におけるオートファジー関連の白の発現と臨床像.2013

    • Author(s)
      今一義.池嶋健一.渡辺純夫.
    • Organizer
      第21回日本消化器関連学会週間(JDDW2013)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] 非アルコール性脂肪性肝疾患患者におけるオートファジー機能障害とカテプシン発現異常2013

    • Author(s)
      福生有華, 山科 俊平, 泉 光輔, 園上 浩司, 荒川 敦, 青山 友則, 内山 明, 今 一義, 鈴木 聡子, 池嶋 健一, 渡辺 純夫
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-24390191
  • [Presentation] 非B非C肝発癌におけるオートファジー関連蛋白の関与.2013

    • Author(s)
      今一義.池嶋健一.渡辺純夫.
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] 肝発癌におけるPtenおよびP62発現と背景肝疾患による相違の検討.2013

    • Author(s)
      今一義.池嶋健一.川崎誠治.渡辺純夫.
    • Organizer
      第49回日本肝癌研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] NAFLD患者における肝カテプシンL発現とオートファジー機能の評価福生有華2012

    • Author(s)
      山科俊平,泉光輔,稲見義宏,山形寿文,今一義,鈴木聡子,池嶋健一,渡辺純夫
    • Organizer
      肝臓(0451-4203)53巻Suppl.3 PageA929
    • Data Source
      KAKENHI-PROJECT-23590989
  • [Presentation] Innate immune responses involving NK and NKT cells promote liver regeneration after partial hepatectomy2011

    • Author(s)
      Hosoya S, Ikejima K, Arai K, Kon K, Yamashina S, Takeda K, Watanabe S
    • Organizer
      Poster Session(Poster of Distinction), The Liver Meeting 2011(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2011-11-07
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Loss of parkin impairs liver regeneration2011

    • Author(s)
      Fukada H, Yamashina S, Izumi K, Nakadera E, Fukuo Y, Uchiyama A, Kon K, Ikejima K, Watanabe S
    • Organizer
      Poster Session, The Liver Meeting 2011(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2011-11-06
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Hepatic NKT cells are progressively depleted in steatohepatitis with tumorigenesis caused by hepatocyte-specific PTEN deficiency2011

    • Author(s)
      Miyaji T, Ikejima K, Hosoya S, Arai K, Kon K, Yamashina S, Watanabe S
    • Organizer
      Poster Session, The Liver Meeting 2011(Annual Meeting of Am Ass ociation for Study of Liver Diseases)
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2011-11-07
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 肝5-11NASHの肝病態に対するウルソール酸の有用性:モデルマウスでの検討.シンポジウム5NASH発症の分子機構と治療標的2011

    • Author(s)
      池嶋健一, 今一義, 渡辺純夫
    • Organizer
      第15回日本肝臓学会大会(JDDW2011)
    • Place of Presentation
      福岡
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Imaired liver regeneration after partial hepatectomy in mice depleting NK and NKT cells2011

    • Author(s)
      Hosoya S, Ikejima K, Arai K, Aoyama T, Kon K, Ishikawa S, Yamagata H, Yamashina S, Suzuki S, Takeda K, Watanabe S
    • Organizer
      Poster Session, 18th International Symposium on Cells of the Hepa Sin usoid(Biannual Meeting of International Society for Hepatic Sinusoidal Research)
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 脂肪性肝炎発症におけるNKT細胞の関与.ワークショップ7 : Steatohepatitis(脂肪肝炎)の病態~その多様性と相同性~2011

    • Author(s)
      池嶋健一, 山形寿文, 渡辺純夫
    • Organizer
      第97回日本消化器病学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 脂肪肝における低酸素暴露後のZone 3優位の酸化ストレスと肝細胞アポトーシス2011

    • Author(s)
      今一義, 池嶋健一, 谷口源太郎, 内山明, 福原京子, 細谷聡子, 山科俊平, 渡辺純夫
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 肝細胞内脂肪滴蓄積とオートファジー機能障害2011

    • Author(s)
      山科俊平、稲見義宏、今一義、池嶋健一、渡辺純夫
    • Organizer
      第47回日本肝臓学会総会ワークショップ
    • Place of Presentation
      東京都ホテルグランパシフィック
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] Mice depleting natural killer T cells are more susceptible to dietary-induced steatohepatitis, Selected Oral Presentation 102011

    • Author(s)
      Ikejima K, Yamagata H, Arai K, Ishikawa S, Hosoya S, Kon K, Yamashina S, Suzuki S, Takeda K, Watanabe S
    • Organizer
      18th International Symposium on Cells of the Hepatic Sinusoid(Biannual Meeting of International Society for Hepatic Sinusoidal Research)
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Mice depleting natural killer T cells are more susceptible to dietary-induced steatohepatitis2011

    • Author(s)
      Ikejima K
    • Organizer
      16^<th> International Symposium on Cells of the Hepatic Sinusoid
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 肝細胞内脂肪滴蓄積とオートファジー機能障害.ワークショップ2 NASH-我が国の実態と発生機序の解明に向けて2011

    • Author(s)
      山科俊平, 稲見義宏, 今一義, 池嶋健一, 渡辺純夫
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Ursolic acid ameliorates hepatic fibrogenesis through induction of apoptosis in hepa Ses sion : Fibrogenesis Experimental2011

    • Author(s)
      Ikejima K, WFukuhara K, Hosoya S, Yamashina S, Watanabe S
    • Organizer
      The International Liver Congress 2011 : 46th Annual Meeting of the European Association for the Study of the Liver(EASL)
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Differential role of natural killer T cell subsets in xenobiotics-induced hepatic inflammation and fibrogenesis2011

    • Author(s)
      Ikejima K, Ishikawa S, Hosoya S, Yamagata H, Arai K, Kon K, Yamashina S, Watanabe S
    • Organizer
      Poster Session(Poster of Distinction), Digestive Disease Week
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] アセトアミノフェン投与後の肝細胞死誘導に対する関与について.アセトアミノフェン投与後の肝細胞死誘導に対する関与について2011

    • Author(s)
      井草祐樹, 山科俊平, 今一義, 池嶋健一, 渡辺純夫
    • Organizer
      アセトアミノフェン投与後の肝細胞死誘導に対する関与について
    • Place of Presentation
      東京
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] High-carbohydrate diet containing trans-fatty acid induces severe steatohepatitis via the enhancement of endoplasmic reticulum stress in KK-Ay mice2010

    • Author(s)
      Saito H, Kon K, Ishikawa S, Hosoya S, Arai K, Takashima M, Yamashina S, Ikejima K, Watanabe S
    • Organizer
      Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Impaired hepatic innate responses involving NKT cells in obese diabetic KK-Ay mice2010

    • Author(s)
      Yamagata H, Ikejima K, Ishikawa S, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
    • Organizer
      Poster Session I Steatohepatitis-NASH, 15^<th> Int ernational Symposium on Cells of International Symposium on Cells of the Hepatic Sinusoid
    • Place of Presentation
      Pasadena, CA, USA
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 肝NKT細胞とCD1d分子による脂肪性肝炎の発症制御メカニズムの解析.ワークショップ3 : NASH/NAFLD発症のメカニズム2010

    • Author(s)
      池嶋健一, 山形寿文, 渡辺純夫
    • Organizer
      第96回日本消化器病学会総会
    • Place of Presentation
      新潟
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Trans-fatty acid induces apoptosis of hepatocytes by enhancement of oxidative stress in steatotic liver of KK-Ay mice2010

    • Author(s)
      Kon K, Ikejima K, Saito H, Ishikawa S, Hosoya S, Arai K, Okumura K, Yamashina S, Watanabe S
    • Organizer
      Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2010-11-01
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 非B非C原発性肝癌の腫瘍マーカーと背景疾患からみた検討.ワークショップ4 :慢性肝疾患からの発癌:背景肝疾患(病理,画像,遺伝子異常を含む)からみた検討2010

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Organizer
      第14回日本肝臓学会大会(JDDW 2010)
    • Place of Presentation
      横浜
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] チオアセタミド誘発性肝障害におけるCD1d拘束性NKT細胞の役割2010

    • Author(s)
      石川幸子, 池嶋健一, 山形寿文, 青山友則, 今一義, 渡辺純夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] アセトアミノフェン投与後肝障害におけるオートファジーの役割の検討2010

    • Author(s)
      井草祐樹, 山科俊平, 今一義, 池嶋健一, 渡辺純夫
    • Organizer
      第14回日本肝臓学会大会(JDDW 2010)
    • Place of Presentation
      横浜
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] MRIによるfat fraction+T2 starを用いた肝脂肪化および鉄含有量の定量的評価2010

    • Author(s)
      福原京子, 池嶋健一, 渡辺純夫
    • Organizer
      第38回日本肝臓学会東部会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Adipocytokines and NASH. Symposium 2 : NASH-Current insights in pathogenesis and clinical aspects. Part 2. Pathogenesis of NASH2010

    • Author(s)
      Ikejima K
    • Organizer
      The Japanese Society of Gastroenterology(JSGE) 2nd International Forum 2. Emerging Issues in AIH & NASH
    • Place of Presentation
      Niigata, Japan
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] CD1d-restricted natural killer T cells contribute to thioacetamide-induced he inf lammation and fibrogenesis in mice2010

    • Author(s)
      Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
    • Organizer
      Parallel Session 11 : Chronic liver injury and fibrosis, The 45th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] アセトアミノフェン投与後肝障害におけるオートファジーの役割の検討2010

    • Author(s)
      井草祐樹、山科俊平、今一義、池嶋健一、渡辺純夫
    • Organizer
      第18回日本消化器関連学会週間
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20590797
  • [Presentation] NASHに関する最近の話題.特別企画【最近の話題】22010

    • Author(s)
      池嶋健一
    • Organizer
      第38回日本肝臓学会東部会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Hepatic steatosis suppresses autophagic proteolysis. Poster Session2010

    • Author(s)
      Yamashina S, Inami Y Ikejima K, Watanabe S
    • Organizer
      2010 International Society for Bi Alc oholism(ISBRA) World Congress
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Depletion of natural killer T cells increases the susceptibility to dietary-induced steatohepatitis in mice2010

    • Author(s)
      Ikejima K, Yamagata H, Arai K, Ishikawa S, Hosoya S, Kon K, Yamashina S, Takeda K, Watanabe S
    • Organizer
      Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2010-11-01
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] ジエチルニトロソアミン投与後肝障害におけるオートファジーの関与について2010

    • Author(s)
      米合古麗阿不都雪克, 山科俊平, 深田浩大, 井草祐樹, 今一義, 池嶋健一, 渡辺純夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 脂肪性肝炎発症における肝NKT細胞とCD1d分子の関与.パネルディスカッション: NASH/NAFLDの病因・病態と予後2010

    • Author(s)
      池嶋健一, 山形寿文, 渡辺純夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] CD1d-restricted natural killer T cells modulate susceptibility to dietary-induced steatohepatitis in mice2010

    • Author(s)
      Ikejima K, Yamagata H, Ishikawa S, Arai K, Aoyama T, Kon K, Takeda K, Watanabe S
    • Organizer
      Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 脂肪性肝炎の病態形成におけるトランス脂肪酸の影響と酸化ストレスの役割.ワークショップ7,肝病態形成におおける酸化ストレスの意義2010

    • Author(s)
      今一義, 池嶋健一, 細谷聡子, 斉藤紘昭, 石川幸子, 柳沼礼子, 山科俊平, 渡辺純夫
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      新潟
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Adipocytokines and NASH.2010

    • Author(s)
      Ikejima K
    • Organizer
      第96回日本消化器病学会総会 第2回国際フォーラム(English Session)
    • Place of Presentation
      新潟
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Contribution of hepatic steatosis and adipokines in resistance formation to the current anti-virral therapy for chronic hepatitis C2010

    • Author(s)
      Ikejima K
    • Organizer
      BIT's 1st World Congress of Virus and Infections(WCVI)-2010
    • Place of Presentation
      Busan, South Korea
    • Year and Date
      2010-08-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Loss of autophagy enhances the sensitization of Kupffer cells to endo toxin2010

    • Author(s)
      Hiroo Fukada, Shunhei Yamashina, Kousuke Izumi, Yoshihiro Inami, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
    • Organizer
      The American association for the study of liver diseases 61th annual meeting and postgraduate course# 1971
    • Place of Presentation
      米国ボストンHynes convention center
    • Year and Date
      2010-11-03
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] Innate immunity and NAFLD/NASH. Session 4 : Immunity and cytokine responses in NASH2010

    • Author(s)
      Ikejima K, Yamagata H, Hosoya S, Ishikawa S, Aoyama T, Kon K, Yamashina S, Suzuki S, Watanabe S
    • Organizer
      The 9th Japan Society of Hepatology(JSH) Single Topic Conference NASH-2010
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Loss of autophagy enhances the sensitization of Kupffer cells to endotoxin2010

    • Author(s)
      Fukada H, Yamashina S, Izumi K, Inami Y, Kon K, Ikejima K, Watanabe S
    • Organizer
      Poster Session Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2010-11-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Loss of autophagy enhances acetaminophen-induced liver injury2010

    • Author(s)
      Igusa Y, Yamashina S, Izumi K, Fukada H, Mikirai A, Inami Y, Kon K, Ikejima K, Watanabe S
    • Organizer
      AASLD Poster Session, Digestive Disease Week(DDW)
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2010-05-02
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Contribution of NK and NKT cells in hepatic regeneration after partial hepatectomy in mice2010

    • Author(s)
      Hosoya S, Ikejima K, Aoyama T, Ishikawa S, Yamagata H, Kon K, Takeda K, Watanabe S
    • Organizer
      Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Hepatic NKT and NK cells regulate liver reg hep atectomy in mice2010

    • Author(s)
      Hosoya S, Ikejima K, Aoyama T, Ishikawa S, Yamagata H, Kon K, Yamashina S, Takeda K, Watanabe S
    • Organizer
      Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2010-11-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Contribution of CD1d-restricted natural killer T cells to xenobiotics-induced hepatic inflammation and fibrogenesis in mice2010

    • Author(s)
      Ikejima K, Ishikawa S, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
    • Organizer
      Session II. Steatohepatitis-II(Oral presentation), 15th International Symposium on Cells of the Hepatic Sinusoid
    • Place of Presentation
      Pasadena, CA, USA
    • Year and Date
      2010-08-29
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Ursolic acid ameliorates dietary steatohepatitis in obese diabetic KK-Ay mice2010

    • Author(s)
      Ikejima K, Piao N, Yamagata H, Kon K, Yamashina S, Watanabe S
    • Organizer
      AASLD Poster Session, Digestive Disease Week(DDW)
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2010-05-02
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Synthetic triglyceride containing an arachidonic acid branch(8A8) minimizes endotoxin-induced liver injury2010

    • Author(s)
      Ikejima K, Piao N, Kon K, Aoyama T, Yamashina S, Takei Y, Sato N, Watanabe S
    • Organizer
      Poster Session, 2010 International Society for Biomedical Research on Alcoholism(ISBRA) World Congress
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] チオアセタミド肝障害の病態形成におけるNKT細胞の関与.ワークショップ12 :肝疾患における免疫病態形成と新たな治療戦略2010

    • Author(s)
      池嶋健一, 石川幸子, 渡辺純夫
    • Organizer
      第14回日本肝臓学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-10-14
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] NAFLDの病態進展における肝内自然免疫機構の関与:メタボリックシンドロームモデル動物を用いた検討ワークショップ12 : NAFLDの経時的進展2009

    • Author(s)
      池嶋健一, 山形寿文, 渡辺純夫
    • Organizer
      第95回日本消化器病学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2009-05-09
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] HBs抗原陰性・HCV抗体陰性の肝細胞癌における臨床的特徴と腫瘍マーカー測定の重要性2009

    • Author(s)
      今一義, 池嶋健一, 青山友則, 山形寿文, 柳沼礼子, 石川幸子, 高島基樹, 山科俊平, 鈴木聡子, 渡辺純夫
    • Organizer
      第95回日本消化器病学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2009-05-09
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] NAFLD関連肝細胞癌の治療にかかわる因子の解明-腫瘍マーカー測定の重要性-ワークショップ1 : NASHは声明予後に影響するか?2009

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Organizer
      第13回日本肝臓学会大会(JDDW 2009)
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] NAFLD患者の低用量ピオグリタゾン療法におけるMRI肝脂肪測定の有用性2009

    • Author(s)
      柳沼礼子, 池嶋健一, 福原京子, 青山友則, 今一義, 山科俊平, 鈴木聡子, 渡辺純夫
    • Organizer
      第45回日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Lipid accumulation inhibits induction of autophagy in the mouse liver2009

    • Author(s)
      Inami Y, Yamashina S, Izumi K, Fukada H, Kon K, Ikejima K, Watanabe S
    • Organizer
      Poster Session, The Liver Meetin Am erican Association for Study of Liver Diseases
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Lipid accumulation inhibits induction of autophagy in the mouse liver2009

    • Author(s)
      Yoshihiro Inami, Shunhei Yamashina, Kousuke Izumi, Hiroo Fukada, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
    • Organizer
      The American association for the study of liver diseases 60th annual meeting and postgraduate course# 1875
    • Place of Presentation
      日米国ボストンHynes convention center
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-21390234
  • [Presentation] 肝内自然免疫系による非アルコール性脂肪性肝炎発症感受性の調節,パネルディスカッション11 :自然免疫と消化器疾患2009

    • Author(s)
      池嶋健一, 山形寿文, 渡辺純夫
    • Organizer
      第13回日本肝臓学会大会(JDDW 2009)
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Ezetimibe prevents metabolic syndrome-related steatohepatitis exacerbated by trans-fatty acid in KK-Ay mice. Poster Session2009

    • Author(s)
      Kon K, Ikejima K, Aoyama T, Ishikawa S, Hosoya S, Arai K, Yamashina S, Watanabe S
    • Organizer
      The Liver Meeting 2009(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Obese diabetic KK-Ay mice are resistant to NKT cell-mediated liver injury induced by a-galactosylceramide2009

    • Author(s)
      Ikejima K, Yamagata H, Takeda K, Aoyama T, Kon K, Yamashina S, Suzuki S, Watanabe S
    • Organizer
      Poster S The 44th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] メタボリックシンドロームモデルKK-Ayマウスにおける肝内NKT細胞分画異常に対するピオグリタゾンの影響2009

    • Author(s)
      山形寿文, 池嶋健一, 青山友則, 今一義, 山科俊平, 渡辺純夫
    • Organizer
      第45回日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 脂肪性肝炎形成における肝細胞内貯蔵鉄の役割-マウス初代培養肝細胞を用いた検討-ワークショップ1, NASH・NAFLDの礎2009

    • Author(s)
      今一義, 池嶋健一, 青山友則, 山形寿文, 内山明, 高島基樹, 石川幸子, 柳沼礼子, 山科俊平, 鈴木聡子, 渡辺純夫
    • Organizer
      第45回日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Increased susceptibility to ethanol-induced liver injury in genetically diabetic KK-Ay mice2009

    • Author(s)
      Ikejima K, Kon K, Yamagata H, Aoyama T, Yamashina S, Suzuki S, Watanabe S
    • Organizer
      AASLD Poster Session, D Di sease Week(DDW)
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Adipokine regulation of innate immunity and tissue repair in steatohepatitis2009

    • Author(s)
      Ikejima K
    • Organizer
      The 4th international symposium on alcoholic liver and pancreatic disease and cirrhosis
    • Place of Presentation
      Hurghada
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Thioacetamide-induced hepatic fibrogenesis is ameliorated in mice genetically disruptive of CD1d2009

    • Author(s)
      Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Takeda K, Watanabe S
    • Organizer
      Poster Session,(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-11-01
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Adipokine regulation of innate immunity and tissue repair in steatohepatitis2009

    • Author(s)
      Ikejima K
    • Organizer
      The 4^<th> international symposium on alcoholic liver and pancreatic disease and cirrhosis
    • Place of Presentation
      Hurghada, Egypt
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] C型慢性肝炎のインターフェロン治療効果規定因子としての肝脂肪化およびアディポカイン発現.パネルディスカッション6 : C型肝炎治療の最前線2009

    • Author(s)
      柳沼礼子, 池嶋健一, 渡辺純夫
    • Organizer
      第95回日本消化器病学会総
    • Place of Presentation
      札幌
    • Year and Date
      2009-05-08
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] He viral response to peg an d ribavirin therapy in Japanese patients with chronic hepatitis C. Poster Session2009

    • Author(s)
      Yaginuma R, Ikejima K, Aoyama T, Yamagata H, Ishikawa S, KonK, Yamashina S, Suzuki S, Watanabe S
    • Organizer
      The 44th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] 脂肪性肝炎の病態進展における肝内自然免疫機構の関与-メタボリックシンドロームモデルKK-Ayマウスを用いた検討2009

    • Author(s)
      池嶋健一, 山形寿文, 石川幸子, 今一義, 渡辺純夫
    • Organizer
      第46回日本消化器免疫学会総会
    • Place of Presentation
      松山
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Pioglitazone improves abnormal expression of hepatic NKT cells in obese and diabetic KK-Ay mice2009

    • Author(s)
      Ikejima K, Yamagata H, Takeda K, Kon K, Aoyama T, Yamashina S, Watanabe S
    • Organizer
      Poster session Conference on NAFLD/NASH and related metabolic disease
    • Place of Presentation
      Bologna, Italy
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] メタボリックシンドロームモデルKK-Ayマウスにおける肝内NKT細胞分画異常のメカニズム解析.ワークショップ3 :免疫担当細胞異常からみた肝疾患の病態2009

    • Author(s)
      山形寿文, 池嶋健一, 渡辺純夫
    • Organizer
      第13回日本肝臓学会大会(JDDW 2009)
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Pioglitazone restores expression and function of hepatic NKT cells in obese and diabetic KK-Ay mice2009

    • Author(s)
      Yamagata H, Ikejima K, Takeda K, Aoyama T, Kon K, Yamashina S, Watanabe S
    • Organizer
      Poster Session, The 44 meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] C型肝炎ウイルス複製におけるニコチンの作用2009

    • Author(s)
      山科俊平, 高島基樹, 青山友則, 柳沼礼子, 今一義, 鈴木聡子, 池嶋健一, 佐藤信紘, 渡辺純夫
    • Organizer
      ポスターセッション,第13回日本肝臓学会大会(JDDW 2009)
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] C型慢性肝炎のペグインターフェロンα-2b・リバビリン併用療法のガイドライン準拠率と治療奏効性の関連2009

    • Author(s)
      柳沼礼子, 池嶋健一, 青山友則, 山形寿文, 石川幸子, 今一義, 山科俊平, 鈴木聡子, 渡辺純夫
    • Organizer
      ポスターセッション,第13回日本肝臓学会大会(JDDW 2009)
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Pioglitazone prevents apoptosis of hepatic NKT cells in obese and diabetic KK-Ay mice2009

    • Author(s)
      Yamagata H, Ikejima K, Takeda K, Kon K, Aoyama T, Yamashina S, Watanabe S
    • Organizer
      Poster Session,(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] Pioglitazone minimizes regeneration failure following partial hepatectomy in obese KK-A^y mice. Poster Session2008

    • Author(s)
      Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Yamagata H, Yamashina S, Watanabe S
    • Organizer
      The Liver Meeting2008 (Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      San Francisco
    • Year and Date
      2008-11-02
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] C-reactive protein attenuates experimental hepatic fibrosis through inhibition of hepatic stellate cells transactivation. Poster Session2008

    • Author(s)
      Ikejima K, Arai K, Kon K, Aoyama T, Okumura K, Yaginuma R, Yamashina S, Watanabe S
    • Organizer
      The 43^<rd> annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] Efficacy of low-dose pioglitazone for the treatment of NAFLD patients in Japan2008

    • Author(s)
      Yaginuma R, Ikejima K, Kon K, Okumura K, Yamashina S, Suzuki S, Watanabe S
    • Organizer
      Poster Session, The Liver Meeting 2009 on(Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      Boston, USA
    • Year and Date
      2008-11-01
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] メタボリックシンドロームにおける肝内参加ストレス応答性更新とそのメカニズム. パネルディスカッション22008

    • Author(s)
      今一義, 池嶋健一, 渡辺純夫
    • Organizer
      日本肝臓学会東部会
    • Place of Presentation
      東京
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] 肝細胞の脂肪沈着とネクローシスに対するトランス脂肪酸の影響. ポスター2008

    • Author(s)
      今一義, 池嶋健一, 青山友則, 山形寿文, 内山明, 柳沼礼子, 山科俊平, 渡辺純夫
    • Organizer
      第44回肝臓学会総会
    • Place of Presentation
      松山
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] C reactive protein(CRP)の肝星細胞活性化抑制を介した抗肝線維化作用. 口演2008

    • Author(s)
      池嶋健一, 今一義, 青山友則, 山形寿文, 柳沼礼子, 山科俊平, 鈴木聡子, 渡辺純夫
    • Organizer
      第44回肝臓学会総会
    • Place of Presentation
      松山
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] TRAIL Receptor DR5-mediated apoptosis signals induce screlosing cholangiopathy in mice2008

    • Author(s)
      Ikejima K, Takeda K, Kojima Y, Aoyama T, Okumura K, Yamashina S, Okumura K, Watanabe S
    • Organizer
      AASLD Research Forum, Digestive Disease Week
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2008-05-18
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] C型慢性肝炎における肝脂肪化およびアディポカイン発現とペグインターフェロン・リバビリン併用療法奏効性. シンポジウム22008

    • Author(s)
      池嶋健一, 柳沼礼子, 渡辺純夫
    • Organizer
      日本肝臓学会東部会
    • Place of Presentation
      東京
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] Altered expression and function of hepatic NKT cells in obese and diabetic KK-A^y mice.2008

    • Author(s)
      Yamagata H, Ikejima K, Takeda K, Aoyama T, kon K, Yamashina S, Watanabe S.
    • Organizer
      Liver Meeting 2008 (AASLD)
    • Place of Presentation
      San Francisco
    • Year and Date
      2008-11-02
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] Altered expression andfunction of hepatic NKT cells in obese and diabetic KK-Ay mice. Parallel Session2008

    • Author(s)
      Yamagata H, Ikejima K, Takeda K, Aoyama T, Kon K, Yamashina S, Watanabe S
    • Organizer
      The Liver Meeting 2008 (Annual Meeting of AmericanAssociation for Study of LiverDiseases)
    • Place of Presentation
      San Francisco
    • Year and Date
      2008-11-02
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] 癌抑制蛋白PTENの肝星細胞活性化に対する抑制効果. ワークショップ82008

    • Author(s)
      高島基樹, 池嶋健一, 塚田重城, 今一義, 金野朗, 山科俊平, 鈴木聡子, 渡辺純夫
    • Organizer
      第44回肝臓学会総会
    • Place of Presentation
      松山
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] 硬化性胆管病変形成におけるTRAIL系免疫機構の役割 : TRAILおよびDR5遺伝子欠損マウスを用いた検討. ワークショップ102008

    • Author(s)
      池嶋健一, 竹田和由, 渡辺純夫
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-09
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] NAFLDに対する低用量ピオグリタゾン投与の有用性. シンポジウム82008

    • Author(s)
      池嶋健一, 柳沼礼子, 渡辺純夫
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-08
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] ジェノタイプ1b型高ウイルス量のC型慢性肝炎におけるpeg-interferon/ribavirin併用療法の宿主側難治性要因 : 肝脂肪化との関連について. 口演2008

    • Author(s)
      鈴木聡子, 池嶋健一, 高島基樹, 水井智和, 山形寿文, 青山友則, 内山明, 柳沼礼子, 今一義, 金野朗, 山科俊平, 松本俊治, 渡辺純夫
    • Organizer
      第44回肝臓学会総会
    • Place of Presentation
      松山
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] KKAyマウスの肝再生不全に対するpioglitazoneの改善作用とそのメカニズム. ワークショップ12008

    • Author(s)
      青山友則, 池嶋健一, 渡辺純夫
    • Organizer
      第50回日本消化器病学会大会(JDDW2008)
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] NAFLD治療におけるピオグリタゾン投与用量の検討 : 低用量投与の有用性について. ポスター2008

    • Author(s)
      柳沼礼子, 池嶋健一, 福原京子, 青山友則, 今一義, 水井智和, 山科俊平, 鈴木聡子, 渡辺純夫
    • Organizer
      第44回肝臓学会総会
    • Place of Presentation
      松山
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] Acetaminophen induces severe liver injury caused by increased susceptibility to oxidative stress in obese KK-Ay mice. Poster Session2008

    • Author(s)
      Kon K, Ikejima K, Aoyama T, Arai K, Yamashina S, Watanabe S
    • Organizer
      The 43^<rd> annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] Involvement of iron in trans-fatty acid-induced accumulation and oxidative stress in mouse hepatocytes. Poster Session2008

    • Author(s)
      Kon K, Ikejima K, Aoyama T, Yamagata H, Arai K, Yamashina S, Watanabe S
    • Organizer
      The LiverMeeting 2008 (Annual Meeting of American Association for Study of Liver Diseases)
    • Place of Presentation
      San Francisco
    • Year and Date
      2008-11-02
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] メタボリック症候群における肝再生不全 : pioglitazoneによる改善効果とそのメカニズムの検討2008

    • Author(s)
      青山友則, 池嶋健一, 今一義, 山形寿文, 柳沼礼子, 山科俊平, 渡辺純夫
    • Organizer
      第44回肝臓学会総会
    • Place of Presentation
      松山
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] NASHの発症・進展におけるC-reactive protein(CRP)の病態生理的意義2007

    • Author(s)
      池嶋 健一, 柳沼 礼子, 渡辺 純夫
    • Organizer
      第11回肝臓学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-20
    • Data Source
      KAKENHI-PROJECT-19590791
  • [Presentation] The role of adipokines in hepatic fibrogenesis in alcoholic and nonalcoholic fatty liver diseases.2006

    • Author(s)
      Ikejima K, Okumura K, Kon K, Aoyama T, Yamashina S, Enomoto N, Takei Y, Sato N
    • Organizer
      International Society of Biomedical Research on Alcoholism (ISBRA)
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2006-09-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Presentation] Liver disorders associated with metabolic syndrome : disease susceptibility and therapeutic resistance.2006

    • Author(s)
      Ikejima K
    • Organizer
      The 32nd Autumn Congress of Korean Diabetic association.
    • Place of Presentation
      Gyeongju, Korea
    • Year and Date
      2006-11-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390213
  • [Presentation] 非B非C肝発癌におけるオートファジー関連蛋白の関与.

    • Author(s)
      今一義.池嶋健一.渡辺純夫
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] フェニル酪酸によるNASH肝発癌抑制効果-NASH発癌モデルマウスを用いた検討.

    • Author(s)
      今一義.池嶋健一.渡辺純夫.
    • Organizer
      第20回JDDW
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] Hepatic steatosis suppresses mitochondrial autophagy

    • Author(s)
      Yamashina S, Inami Y, Uchiyama A, Kon K, Ikejima K, Watanabe S
    • Organizer
      Poster Session 1 : Animal Models and Pathogenesis-1, 6th International Symposium on Alcoholic Liver and Pancreatic Diseases Cirrohosis
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21590859
  • [Presentation] The chemical chaperon 4-phenylbutyrate prevents epigenetic alterations and carcinogenesis in NASH-HCC model mice

    • Author(s)
      Kon K, Ikejima K, Uchiyama A, Aoyama T, Arai K, Morinaga M, Yamashina S, Watanabe S
    • Organizer
      欧州肝臓学会(EASL)
    • Place of Presentation
      イギリス ロンドン
    • Year and Date
      2015-04-09 – 2015-04-13
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] The chemical chaperon 4-phenylbutyrate inhibits liver fibrosis and tumorgenesis in high -fat diet with N-acetyI-β-D-glucosaminedase inhibitor-induced NASH model mice.

    • Author(s)
      Kon K.Ikejima K.Hosoya S.Arai K.Uchiyama A.Yamashina S.Watanabe S.
    • Organizer
      DDW
    • Place of Presentation
      米国サンディエゴ
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] Role of NK and NKT cells in the pathogenesis and carcinogenesis in steatohepatitis.

    • Author(s)
      Ikejima, K, Miyaji T, Hosoya S, Arai K, Kon K, Yamashina S, Watanabe S.
    • Organizer
      16th Congress of International Society for Biomedical Research on Alcoholism
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] Induction of apoptosis in hepatic stellate cells as a treatment strategy for hepatic fibrosis.

    • Author(s)
      Ikejima K, Wang X, Arai K, Kon K, Yamashina S, Watanabe S.
    • Organizer
      16th Congress of International Society for Biomedical Research on Alcoholism.
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] Mechanisms of fibrogenesis in NASH

    • Author(s)
      Ikejima K.
    • Organizer
      4th Kokata Liver Meeting
    • Place of Presentation
      Kolkata, India
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] Pathophysiological role of adipocytokines in the digestive system.

    • Author(s)
      Ikejima K, Kon K, Yamashina S, Watanabe S.
    • Organizer
      The 3rd Asian-Pacific Topic Conference
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] 脂肪性肝炎の共通病態基盤としての肝内自然免疫系の関与

    • Author(s)
      池嶋健一,今一義,山科俊平,渡辺純夫
    • Organizer
      第12回日本抗加齢医学会総会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590996
  • [Presentation] The expression of autophagy-related proteins in non-B non-C hepatocellular carcinogenesis

    • Author(s)
      Kazuyoshi Kon, Kenichi Ikejima, Akira Uchiyama, Shunhei Yamashina, Sumio Watanabe
    • Organizer
      DDW
    • Place of Presentation
      米国オーランド
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] 非B非C肝癌におけるPtenおよびP62の発現の変化

    • Author(s)
      今一義.池嶋健一.内山明.山形寿文.細谷聡子.高嶋志在.鈴木聡子.山科俊平.渡辺純夫.
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      石川県
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] The chemical chaperone 4-phenylbutyric acid attenuates trans-fatty acid-induced ER stress and hepatic lipotoxicity.

    • Author(s)
      Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
    • Organizer
      THE 3RD ASIAN-PACIFIC TOPIC CONFERENCE
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590995
  • [Presentation] Inhibition of endoplasmic reticulum stress by 4-phenylbutyrate prevents steatohepatitis progression and tumorigenesis in NASH-HCC model mice.

    • Author(s)
      Kon K.Ikejima K.Uchiyama A.Arai K.Yamashina S.Watanabe S.
    • Organizer
      AASLD
    • Place of Presentation
      米国ボストン
    • Data Source
      KAKENHI-PROJECT-24590995
  • 1.  KON Kazuyoshi (30398672)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 187 results
  • 2.  YAMASHINA Shunhei (30338412)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 91 results
  • 3.  TAKEI Yoshiyuki (10306954)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 41 results
  • 4.  ENOMOTO Nobuyuki (20348973)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 32 results
  • 5.  WATANABE Sumio (20138225)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 6.  SATO Nobuhiro (90028358)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 17 results
  • 7.  HIROSE Miyoko (70266039)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  UENO Takashi (10053373)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 9.  OGIHARA Tatuo (80011196)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TAKEDA Kazuyoshi (80272821)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 11.  李 賢哲 (30758321)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 12.  TSUKADA Shigeki (40420848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  KAWAKAMI Kyojiro (90589227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SUEMIZU Hiroshi (40332209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TERAI Takeshi (90245704)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KITAMURA Tsuneo (20231285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  FUJITA Toshiko (00100131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OHKUSA Toshifumi (50160445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MARUYAMA Atsushi (40190566)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 20.  HORIE Yasuo (30282164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  OHSHIMA Shigetoshi (50375268)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Uchiyama Akira (60529254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 23.  鈴木 聡子 (20317431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  岩渕 和久 (10184897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  千葉 麻子 (40532726)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  TAKASHIMA Motoki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  小野 正文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 28.  西原 利治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 29.  水田 洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  小池 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  横溝 岳彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  青山 友則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  中島 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  和田 孝一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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