TAKEDA KAZUYOSHI 竹田和由

… Alternative Names

Researcher Number	80272821
Other IDs
Affiliation (Current)	2021: 順天堂大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help	2015 – 2021: 順天堂大学, 医学(系)研究科(研究院), 准教授 2015: 順天堂大学, 大学院医学研究科, 准教授 2007 – 2013: Juntendo University, Immunology, Associate professor 2001 – 2006: 順天堂大学, 医学部, 講師 1996: 新潟大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Immunology / Tumor immunology / Tumor therapeutics / Medium-sized Section 50:Oncology and related fields Except Principal Investigator Gastroenterology / Pathobiological dentistry/Dental radiology / General pharmacology / Experimental pathology / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator TRAIL / NK細胞 / IFN-γ / DR5 / NKT細胞 / α-galactosylceramide / CTL / ICOS / 腫瘍免疫 / CD94 … More Except Principal Investigator TWEAK / アポトーシス / 自然免疫 / メタボリックシンドローム / NKT細胞 / 癌抑制分子 / ケモカインCXCL14/BRAK / 発癌抑制 / 転移抑制 / Fn14 / マラリア / ネズミマラリア / 胸腺外分化T細胞 / NK1.1^+T細胞 / 肝 / 顆粒球 / ヒトマラリア / 初期防御 / 抗腫瘍免疫 / TRAIL / DR5 / 腫瘍細胞 / 局在 / がん抗体療法 / 胆管閉塞 / Importin β1 / PSC / TRAILレセプター / 非アルコール性脂肪肝炎(NASH) / 肝線維化 / 肝再生 / NK細胞 / CD1d / アディポカイン / チアゾリジン系誘導体 / 実験腫瘍学 / 実験的発癌 / 癌抑制因子 / 細胞接着分子 / 腫瘍 / サイトカイン / 血管新生 / 腫瘍拒絶 / IκBα / IL-8 / GM-CSF / RANTES / 炎症 / tumor / apoptosis / cytokine / angiogenesis / tumor rejection / 自己免疫疾患 / 関節炎モデル / 実験的自己免疫性ぶどう膜網膜炎 / OVA誘発性喘息 / 実験的自己免疫性脳脊髄炎 / 補助シグナル分子 / CD28-B7ファミリー / TNF-TNFRファミリー / コラーゲン誘発性関節炎 / B7RP-1 / autoimmune diseases / collagen-induced arthritis / experimental autoimmune uveoretinitis / murine model of asthma / experimental autoimmune encephalomyelitis / costimulatory molecules / CD28-B7 family / TNF-TNFR family / ケモカイン / 副作用のない癌抑制法 / 余命の延長 / がん抑制分子 / 多段階がん抑制性ケモカイン / 多機能がん抑制性ケモカイン / ケモカインCXCL14 / CXCL14 / 寿命の延長 / 非アルコール性脂肪肝炎（NASH） / 腸内マイクロバイオーム / アミノ酸 / 免疫栄養 / 耐糖能異常 / 非アルコール性脂肪肝炎（NASH) / 糖代謝 / インスリン / 腸内細菌叢 / RIG-I Less

癌と免疫の相互作用による癌細胞の変異と免疫抑制能獲得機構の解析Principal InvestigatorOngoing
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
Analysis of cancer microenvironment under the growth control by anti-tumor immune responsePrincipal Investigator
- Principal Investigator
  
  TAKEDA Kazuyoshi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Juntendo University
Analysis of molecular mechanisms underlying acquired resistance of tumor cells responding to anti-tumor immunityPrincipal InvestigatorOngoing
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
Analysis of B cell receptors expressed on tumor infiltrating B cells by next generation sequencingPrincipal Investigator
- Principal Investigator
  
  TAKEDA KAZUYOSHI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Juntendo University
Innate immune regulation in metabolic steatohepatitis and experimental therapeutics
- Principal Investigator
  
  Ikejima Kenichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Investigation of cancer therapeutic method without side effects: Suppression mechanisms of cancer metastasis on the lung by CXCL14/BRAK
- Principal Investigator
  
  Hata Ryu-Ichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Kanagawa Dental College
From cancer therapeutics to cancer prevention: Investigation of suppression mechanisms of tumor growth and metastasis in cancer resistant mouse
- Principal Investigator
  
  HATA Ryu-Ichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Kanagawa Dental College
がん微小環境により癌が免疫耐性を新規に獲得する機構の解析Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Analysis of tumor-rejecting biological reactions induced by tumor specific immune responsesPrincipal Investigator
- Principal Investigator
  
  TAKEDA Kazuyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor immunology
- Research Institution
  Juntendo University
Role of innate immune system in the regulation of hepatic metabolism and pathogenesis of steatohepatitis
- Principal Investigator
  
  IKEJIMA Kenichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
免疫による癌拒絶局所での分子機構の解析Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Development of novel cancer therapy by combination of immune activation with tumor apoptosis inductionPrincipal Investigator
- Principal Investigator
  
  KAZUYOSHI Takeda
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
Contribution of intracellular TRAIL receptor to regulation of apoptosis induced by TRAIL
- Principal Investigator
  
  KOJIMA Yuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
Functional analysis of costimulatory molecules for autoimmune diseases
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
NK細胞、NKT細胞の機能調節による感染防御機構の制御Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
NK細胞、NKT細胞の機能分子による抗腫瘍免疫制御の解析Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
REGULATION OF TUMOR VESSEL FORMATION BY THE IMMUNE SYSTEM
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  JUNTENDO UNIVERSITY
Investigation into regulation of immune responses by NK cells and NKT cellsPrincipal Investigator
- Principal Investigator
  
  TAKEDA Kazuyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  JUNTENDO UNIVERSITY
NK細胞、NKT細胞の機能調節による感染防御機構の制御Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
NKT細胞による免疫系制御システムの解析Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
NK,NKT細胞による腫瘍拒絶および発癌監視機構の解析Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
NK,NKT細胞による腫瘍拒絶機構の解析Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
ネズミマラリア感染防御における胸腺外分化T(NK1.1^+T)細胞の関与
- Principal Investigator
  
  安保徹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Niigata University
胸腺外分化T(NK1.1^+T)細胞による自己免疫疾患の制御Principal Investigator
- Principal Investigator
  
  竹田和由
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Niigata University

[Book] 炎症・再生医学事典(編集:松島綱治、西脇徹)(10.NK細胞)2009
- Author(s)
  竹田和由
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20590494
[Book] 講義録(編集:高橋和久)(腫瘍学I.腫瘍を深く知るための基本講義A.癌に関する基礎知識を学ぶ免疫学)2009
- Author(s)
  竹田和由
- Publisher
  MEDICAL VIEW社
- Data Source
  KAKENHI-PROJECT-20590494
[Book] 金芳堂がん転移研究の実験方法(編:日本がん転移学会)(第III部癌細胞の宿主への影響の研究法第3章癌細胞の産生する液性因子の測定法1.癌細胞の免疫担当細胞への影響の研究法)2008
- Author(s)
  竹田和由
- Data Source
  KAKENHI-PROJECT-20590494
[Book] 第12回東京肝臓シンポジウム講演集(編集:藤原研司、石井裕正、佐藤信紘、荒川泰行、井廻道夫)(自然免疫と生体防御TRAIL:発癌サーベイランスと治療への応用)2008
- Author(s)
  竹田和由
- Publisher
  自然科学社
- Data Source
  KAKENHI-PROJECT-20590494
[Book] がん医療入門(編集:樋野興夫,木南英紀)(第1編腫瘍学の基礎2.腫瘍免疫学-基礎腫瘍学総論2-)2008
- Author(s)
  竹田和由、奥村康
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Phase II adjuvant cancer-specific vaccine therapy for esophageal cancer patients curatively resected after preoperative therapy with pathologically positive nodes; possible significance of tumor immune microenvironment in its clinical effects.2020
- Author(s)
  Yasuda, T., Nishiki, K., Hiraki, Y., Kato, H., Iwama, M., Shiraishi, O., Yasuda, A., Shinkai, M., Kimura, Y., Sukegawa, Y., Chiba, Y., Imano, M., Takeda, T., Satou, T., Shiozaki, H., and Nakamura, Y.
- Journal Title
  
  Annals of Surgery
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02695
[Journal Article] Inhibition of Importin β1 Augments the Anticancer Effect of Agonistic Anti-Death Receptor 5 Antibody in TRAIL-resistant Tumor Cells.2020
- Author(s)
  Yuko Kojima, Takashi Nishina, Hiroyasu Nakano, Ko Okumura, Kazuyoshi Takeda
- Journal Title
  
  Mol. Cancer Ther.
  
  Volume: 19-5 Pages: 1123-1133
- DOI
  10.1158/1535-7163.mct-19-0597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07648, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-18K19483
[Journal Article] Phase II adjuvant cancer-specific vaccine therapy for esophageal cancer patients curatively resected after preoperative therapy with pathologically positive nodes; possible significance of tumor immune microenvironment in its clinical effects.2020
- Author(s)
  Yasuda, T., Nishiki, K., Hiraki, Y., Kato, H., Iwama, M., Shiraishi, O., Yasuda, A., Shinkai, M., Kimura, Y., Sukegawa, Y., Chiba, Y., Imano, M., Takeda, T., Satou, T., Shiozaki, H., and Nakamura, Y.
- Journal Title
  
  Annals of Surgery
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19483
[Journal Article] Stromal fibroblasts induce metastatic tumor cell clusters via epithelial?mesenchymal plasticity2019
- Author(s)
  Matsumura Y, Ito Y, Mezawa Y, Sulidan K, Daigo Y, Hiraga T, Mogushi K, Wali N, Suzuki H, Itoh T, Miyagi Y, Yokose T, Shimizu S, Takano A, Terao Y, Saeki H, Ozawa M, Abe M, Takeda S, Okumura K, Habu S, Hino O, Takeda K, Hamada M, Orimo A.
- Journal Title
  
  Life Sci. Alliance
  
  Volume: 2(4):e201900425. Pages: 1-24
- DOI
  10.26508/lsa.201900425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K07207, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-19K07884, KAKENHI-PROJECT-18K19656, KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-19H03559, KAKENHI-PROJECT-18K19483, KAKENHI-PROJECT-19K21278, KAKENHI-PROJECT-16H05879
[Journal Article] Effect of oral consumption of Panax ginseng aqueous extract on natural killer cell cytotoxicity in human.2019
- Author(s)
  Takeda, K., and Okumura, K.
- Journal Title
  
  Pers. Medi. Univers.
  
  Volume: 8 Pages: 20-26
- DOI
  10.1016/j.pmu.2018.09.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-18K19483
[Journal Article] CD96 is immune checkpoint that regulated CD8+ T-cell antitumor function. Cancer Immunol.2019
- Author(s)
  Mittal, D., Lepletier, A., Madore, J., Aguilera, A. R., Stannard, K., Blake, S. J., Whitehall, V. J. L., Liu, C., Bettington, M. L., Takeda, K, Long, G. V., Scolyer, R. A., Lan, R., Siemers, N., Korman, A., Teng, M. W. L., Johnston, R. J., Dougall, W. C., and Smyth, M. J.
- Journal Title
  
  Cancer Immunol. Res.
  
  Volume: 7 Pages: 559-571
- DOI
  10.1158/2326-6066.cir-18-0637
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-18K19483
[Journal Article] Experimental lung metastases in mice are more effectively inhibited by blockade of IL-23R than IL-23.2018
- Author(s)
  Yan, J., Allen, S., Vijayan, D., Li, X. Y., Harjunpaa, H., Takeda, K., Liu, J., Cua, D. J., Smyth, M. J., and Teng, M. W. L.
- Journal Title
  
  Cancer Immunol. Res.
  
  Volume: 6 Pages: 978-987
- DOI
  10.1158/2326-6066.cir-18-0011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19483, KAKENHI-PROJECT-18H02695
[Journal Article] CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms.2018
- Author(s)
  Li, X. Y., Das, I., Lepletier, A., Addala, V., Bald, T., Stannard, K., Barkauskas, D, Liu, J., Aguilera A. R., Takeda, K., Braun, M., Nakamura, K., Jacquelin, S., Steven W. Lane, S. W., Teng, M. W. L., Dougal, W. C., and Smyth, M. J.
- Journal Title
  
  J. CIin. Invest.
  
  Volume: 128 Pages: 2613-2625
- DOI
  10.1172/jci98769
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19483, KAKENHI-PROJECT-18H02695
[Journal Article] Quantitative T cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination.2018
- Author(s)
  Takeda Kazuyoshi、Kitaura Kazutaka、Suzuki Ryuji、Owada Yuki、Muto Satoshi、Okabe Naoyuki、Hasegawa Takeo、Osugi Jun、Hoshino Mika、Tsunoda Takuya、Okumura Ko、Suzuki Hiroyuki
- Journal Title
  
  Cancer Immunol. Immunother.
  
  Volume: 67 Pages: 946-964
- DOI
  10.1007/s00262-018-2152-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10607, KAKENHI-PROJECT-18K19483, KAKENHI-PROJECT-18H02695
[Journal Article] Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis.2017
- Author(s)
  Putz, E. M., Guillerey, C., Kos, K., Stannard, K., Miles, K., Delconte, R. B., Takeda, K., Nicholson, S. E., Huntington, N. D. 6 Smyth, M. J.
- Journal Title
  
  Oncoimmunology
  
  Volume: 6
- DOI
  10.1080/2162402x.2016.1267892
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.2017
- Author(s)
  Obara, W., Karashima, T., Takeda, K., Kato, R., Kato, Y., Kanehira, M., Takata, R., Inoue, K., Katagiri, T., Shuin, T., Nakamura, Y. & Fujioka, T.
- Journal Title
  
  Cancer Immunol. Immunother.
  
  Volume: 66 Pages: 17-24
- DOI
  10.1007/s00262-016-1915-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting2017
- Author(s)
  Takeda K, Nakayama M, Hayakawa Y, Kojima Y, Ikeda H, Imai N, Ogasawara K, Okumura K, Thomas DM, Smyth MJ
- Journal Title
  
  Nature Communications
  
  Volume: 8 Pages: 14607-14607
- DOI
  10.1038/ncomms14607
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06497, KAKENHI-PROJECT-16H02960, KAKENHI-PROJECT-16H05530, KAKENHI-PROJECT-26460397, KAKENHI-PROJECT-15K14410, KAKENHI-PROJECT-16K15112, KAKENHI-PROJECT-15H04918
[Journal Article] Improved efficacy of neoadjuvant compared to adjuvant immunotherapy to eradicate metastatic disease.2016
- Author(s)
  Liu, J., Blake, S. J., Yong, M. C., Harjunpaa, H., Ngiow, S. F., Takeda, K., Young, A., O’Donell, J. S., Allen, S., Smyth, M.J., & Teng, M. W. L.
- Journal Title
  
  Cancer Discov.
  
  Volume: 6 Pages: 1382-1399
- DOI
  10.1158/2159-8290.cd-16-0577
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors2016
- Author(s)
  Murahashi, M., Hijikata, Y., Yamada, K., Tanaka, Y., Kishimoto, J., Inoue, H., Marumoto, T., Takahazhi, A., Okazaki, T., Takeda, K., Hirakawa, M., Fujii, H., Okano, S., Morita, M., Baba, E., Mizumoto, K., Maehara, Y., Tanaka, M., Akashi, K., Nakanishi, Y., Yoshida, K., Tsunoda, T., Tamura, K., Nakamura, Y., & Tani, K.
- Journal Title
  
  Clin. Immunol.
  
  Volume: 166-167 Pages: 48-58
- DOI
  10.1016/j.clim.2016.03.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14410, KAKENHI-PROJECT-16K07141
[Journal Article] Suppression of metastasis using a new lymphocyte checkpoint target for cancer immunotherapy.2016
- Author(s)
  Blake, S. J., Stannard, K., Liu, J., Allen, S., Yong, M. C., Mittal, D., Aguilera, A. R., Miles, J. J., Lutzky, V. P., de Andrade, L. F., Martinet, L., Colonna, M., Takeda, K., Kuhnel, F., Gurlevik, E., Bernhardt, G., Teng, M. W., & Smyth, M. J.
- Journal Title
  
  Cancer Discov.
  
  Volume: 6 Pages: 446-459
- DOI
  10.1158/2159-8290.cd-15-0944
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] Assessing immune-related adverse events of efficacious combination immunotherapies in preclinical models of cancer.2016
- Author(s)
  Liu, J., Blake, S. J., Harjunpaa, H., Fairfax, K. A., Yong, M. C., Allen, S., Kohrt, H. E., Takeda, K., Smyth, M. J., & Teng, M. W. L.
- Journal Title
  
  Cancer Res.
  
  Volume: 76 Pages: 5288-5301
- DOI
  10.1158/0008-5472.can-16-0194
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] Agonists of the TRAIL death receptor DR5 sensitize intestinal stem cells to chemotherapy-induced cell death and trigger gastrointestinal toxicity.2016
- Author(s)
  Finnberg, N. K., Gokare, P., Navaraj, A., Lang Luhs K. A., Cerniglia, G., Yagita, H., Takeda, K., Motoyama, N., and EL-Deiry, W. S.
- Journal Title
  
  Cancer Res
  
  Volume: 76 Pages: 700-712
- DOI
  10.1158/0008-5472.can-15-2759
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410, KAKENHI-PROJECT-26290059
[Journal Article] Co-inhibition of CD73 and A2AR adenosine signaling improves anti-tumor immune responses.2016
- Author(s)
  Young, A., Ngiow, S. F., Barkauskas, D. S., Sult, E., Hay, C., Stephen J. Blake, S. J., Huang, Q., Liu, J., Takeda, K., Teng, M. W. L., Sachsenmeier, K., & Smyth, M. J.
- Journal Title
  
  Cancer Cell
  
  Volume: 30 Pages: 391-403
- DOI
  10.1016/j.ccell.2016.06.025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] NK cells require IL-28R for optimal in vivo activity.2015
- Author(s)
  Souza-Fonseca-Guimaraes, F., Young, A., Mittal, D., Martinet, L., Bruedigam, C., Takeda, K., Degli-Esposti, M., Andoniou, C. E., Hill, G. R. and Smyth, M.J.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 112
- DOI
  10.1073/pnas.1424241112
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] Toll-Like Receptor 3 regulates NK cell responses to cytokines and controls experimental metastasis.2015
- Author(s)
  Guillerey, C., Chow, M. T., Miles, K., Olver, S., Sceneay, J., Takeda, K., Mollere, A. and Smyth, M.J.
- Journal Title
  
  OncoImmunology
  
  Volume: 4
- DOI
  10.1080/2162402x.2015.1027468
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] High-dose cyclophosphamide induces specific tumor immunity with conccomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites2015
- Author(s)
  Naito, T., Baba, T., Takeda, K., Sasaki, S., Nakamoto, Y. and Mukaida, N.
- Journal Title
  
  Cancer Lett
  
  Volume: 366 Pages: 93-99
- DOI
  10.1016/j.canlet.2015.06.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14410, KAKENHI-PROJECT-26670379, KAKENHI-PROJECT-15K18406, KAKENHI-PROJECT-25460492, KAKENHI-PROJECT-25293171
[Journal Article] Interferon-γ-Mediated Natural Killer Cell Activation by an Aqueous Panax ginseng Extract.2015
- Author(s)
  Takeda, K. and Okumura, K.
- Journal Title
  
  eCAM
  
  Volume: 2015 Pages: 1-11
- DOI
  10.1155/2015/603198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14410
[Journal Article] Suppressed rate of carcinogenesis and decreases in tumour volume and lung metastasis in CXCL14/BRAK transgenic mice.2015
- Author(s)
  Hata R, Izukuri K, Kato Y, Sasaki S, Mukaida N, Maehata Y, Miyamoto C, Akasaka T, Yang X, Nagashima Y, Takeda K, Kiyono T, Taniguchi M.
- Journal Title
  
  Sci Rep
  
  Volume: 5 Pages: 9083-9083
- DOI
  10.1038/srep09083
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23229005, KAKENHI-PROJECT-24659842, KAKENHI-PROJECT-25293384, KAKENHI-PROJECT-25870841, KAKENHI-PROJECT-26460456
[Journal Article] A phase I clinical trial of vaccination with KIF20A-derived peptide in combination with gemcitabine for patients with advanced pancreatic cancer.2014
- Author(s)
  Suzuki N, Hazama S, Ueno T, 他全10名
- Journal Title
  
  J. Immunother.
  
  Volume: 37 (1) Pages: 36-42
- DOI
  10.1097/cji.0000000000000012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355
[Journal Article] A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome2014
- Author(s)
  Hazama, S., Nakamura, Y., Takeuchi, H., Suzuki, N., Tsunedomari, R., Inoue, Y., Iizuka, N., Yoshino, S., Takeda, K., Shinozaki, H., Kamiya, A., Furukawa, H., and Oka, M.
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 12 Pages: 63-63
- DOI
  10.1186/1479-5876-12-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-25861192
[Journal Article] Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer.2014
- Author(s)
  Aruga A, Takeshita N, Kotera Y, 他全9名
- Journal Title
  
  J. Transl. Med.
  
  Volume: 12(1) Pages: 61-61
- DOI
  10.1186/1479-5876-12-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355
[Journal Article] Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophagealcancer patients.2014
- Author(s)
  Iinuma H, Fukushima R, Inaba T,他全15名
- Journal Title
  
  J Transl Med
  
  Volume: 12(1) Pages: 84-84
- DOI
  10.1186/1479-5876-12-84
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-24591984, KAKENHI-PROJECT-25462038
[Journal Article] Phase I clinical trial of apeptide vaccine combinated with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer.2013
- Author(s)
  Matsusita N, Aruga A, Inoue Y, Kotera Y, Takeda K, Yamamoto M
- Journal Title
  
  Oncol. Rep.
  
  Volume: 29 (3) Pages: 951-959
- DOI
  10.3892/or.2013.2231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355, KAKENHI-PUBLICLY-23112519
[Journal Article] A unique dermal dendritic cell subset that skews the immune response toward Th2.2013
- Author(s)
  Kei Takahashi, Kazuyoshi Takeda, Ikuo Saiki, Tatsuro Irimura and Yoshihiro Hayakawa
- Journal Title
  
  Plos One
  
  Volume: 104 Pages: 558-562
- DOI
  10.1111/cas.12112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10991, KAKENHI-PROJECT-21390018, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23701073, KAKENHI-PROJECT-24659029, KAKENHI-PROJECT-24659348, KAKENHI-PROJECT-25293011
[Journal Article] Immunological responses to a multi-target vaccine composed of peptides of cancer testis antigens and vascular endothelial growth factor receptors in patients with advanced pancreatic cancer.2013
- Author(s)
  Okuyama R, Aruga A, Hatori T,Takeda K, Yamamoto M
- Journal Title
  
  OncoImmunology
  
  Volume: 2(11)
- DOI
  10.4161/onci.27010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355
[Journal Article] Phase I/II clinical trial using HLA-A24-restricted peptide vaccine derived from KIF20A for patients with advanced pancreatic cancer.2013
- Author(s)
  Asahara S, Takeda K, Yamao K, Maguchi H, Yamaue H
- Journal Title
  
  J. Transl. Med.
  
  Volume: 11 Pages: 291-291
- DOI
  10.1186/1479-5876-11-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355
[Journal Article] Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer.2013
- Author(s)
  Suzuki H, Fukuhara M, Yamaura T, 他全16名
- Journal Title
  
  J Transl Med.
  
  Volume: 11(1) Pages: 97-97
- DOI
  10.1186/1479-5876-11-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-25462182
[Journal Article] Targeting spatiotermporal expression of CD137 on tumor-infiltrating cytotoxic T lymphocytes as a novel strategy for agonistic antibody therapy.2012
- Author(s)
  Noji S, Hosoi A, Takeda K, Matsushita H, Morishita Y, Seto Y, Kakimi K.
- Journal Title
  
  J Immunother
  
  Volume: 35(6) Pages: 460-472
- DOI
  10.1097/cji.0b013e31826092db
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300332, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-24501329, KAKENHI-PUBLICLY-23112519
[Journal Article] Early activation and interferon-γ production of tumor-infiltrating mature CD27 high natural killer cells.2011
- Author(s)
  Y.Hayakawa
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 1967-1971
- DOI
  10.1111/j.1349-7006.2011.02042.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-22659016, KAKENHI-PUBLICLY-23112519, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23701073
[Journal Article] IFN-γproduction by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice.2011
- Author(s)
  Takeda, K., Nakayama, M., et al
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 90 Pages: 777-785
- DOI
  10.1189/jlb.0411208
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112519, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23701073
[Journal Article] CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice2011
- Author(s)
  Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Journal Title
  
  J Hepatol
  
  Volume: 54(6) Pages: 1195-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Natural killer (NK)- dendritic cell interactions generate MHC class II-dressed NK cells that regulate CD4^+ T cells2011
- Author(s)
  Nakayama M, et al
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 108 Pages: 18360-18365
- DOI
  10.1073/pnas.1110584108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390114, KAKENHI-PROJECT-22659057, KAKENHI-PUBLICLY-23112519, KAKENHI-PROJECT-23300355
[Journal Article] Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo.2010
- Author(s)
  Inami K., Abe M., Takeda K., 他
- Journal Title
  
  Cancer Sci 101
  
  Pages: 969-974
- NAID
  10026591120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Contribution of B7RP-1/iCOS co-stimulation to lethal acute GVHD.2010
- Author(s)
  Fujimura J., Takeda K., Kaduka Y., 他
- Journal Title
  
  Pediatr.Transplant 14
  
  Pages: 540-548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.2010
- Author(s)
  Takeda K., Kojima Y., Uno, 他
- Journal Title
  
  J.Immunol 184
  
  Pages: 5493-5501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] 自己免疫疾患の発症とTRAIL2010
- Author(s)
  竹田和由
- Journal Title
  
  臨床免疫・アレルギー科 53
  
  Pages: 461-467
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Organ microenvironment plays significant roles through Fas ligand in vaccine-induced CD4+ T cell dependent suppression of tumor growth at the orthotopic site.2010
- Author(s)
  Sugiura D., Denda-Nagai K., Takeda K., 他
- Journal Title
  
  Cancer Sci 101
  
  Pages: 1965-1969
- NAID
  10027831307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.2010
- Author(s)
  Takeda, K., et al.
- Journal Title
  
  J.Immunol.
  
  Volume: 184 Pages: 5493-5501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] 抗体カクテル療法による癌治療2009
- Author(s)
  竹田和由
- Journal Title
  
  最新免疫研究Update-免疫システム研究から免疫疾患の病態制御・治療へ医学のあゆみ・別冊
  
  Pages: 63-67
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] NKG2A inhibits invariant NKT cell activation in hepatic injury.2009
- Author(s)
  Kawamura T., Takeda K., Kaneda H., 他
- Journal Title
  
  J.Immunol 182
  
  Pages: 250-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.2009
- Author(s)
  Nakayama M., Akiba H., Takeda K., 他
- Journal Title
  
  Blood 113
  
  Pages: 3821-3830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] IFN-γ-dependent recruitment of mature CD27^<high> NK cells to lymph nodes primed by dendritic cells.2008
- Author(s)
  Watt S.V., Andrews D.M., Takeda K., 他
- Journal Title
  
  J.Immunol 181
  
  Pages: 5323-5330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.2008
- Author(s)
  Takeda, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 105
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] 免疫と癌/乳酸菌によるNK細胞の活性化2008
- Author(s)
  竹田和由
- Journal Title
  
  ヘルシスト 192
  
  Pages: 8-12
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] TRAILレセプター抗体CD40抗体および4-1BB抗体の併用による腫瘤拒絶2008
- Author(s)
  竹田和由
- Journal Title
  
  Annual review Immunology 2008
  
  Pages: 232-239
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease2008
- Author(s)
  Takeda, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 105
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060022
[Journal Article] Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.2008
- Author(s)
  Takeda K., Kojima Y., Ikejima K., 他
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 105
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] 癌細胞死誘導療法とNKT細胞を介した免疫活性化療法の併用効果2008
- Author(s)
  竹田和由
- Journal Title
  
  医学のあゆみ 225
  
  Pages: 167-170
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Runx proteins are involved in regulation of CD 122, Ly49 family and IFN-gamma expression during NK cell differentiation2008
- Author(s)
  Ohno, S., T., Sato, K., Kohu, K., Takeda, K., Okumura, M., Satake, S., Habu
- Journal Title
  
  International immunology 20
  
  Pages: 71-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Correlation between loss of Bel-XL expression and improved prognosis in advances esophageal cancer treated by preoperative chemoradiotherapy.2008
- Author(s)
  Okumura M., Kajiyama Y., Takeda K., 他
- Journal Title
  
  Eur.Surg.Res 41
  
  Pages: 260-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article]2008
- Author(s)
  Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K, Aoyama T, Fress S, Ikeda H, Hynes NM, Cretney E, Yagita H, Sueyoshi N, Sato N, Nakanuma Y, Smyth MJ, Okumura K
- Journal Title
  
  Proc Natl Sci USA 105(31)
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590257
[Journal Article] 抗体カクテルを用いた細胞死誘導と免疫活性化による新規癌治療法の開発2008
- Author(s)
  竹田和由
- Journal Title
  
  リンパ学 31
  
  Pages: 53-55
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.2008
- Author(s)
  Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K, Aoyama T, Frese s, Ikeda H, Hynes NM, Cretney E, Yagita H, Sueyoshi N, Sato N, Nakanuma Y, Smyth MJ, Okumura K
- Journal Title
  
  Proc Natl Acad Sci U S A 105(31)
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590257
[Journal Article] 抗体カクテル療法によるがん治療2008
- Author(s)
  竹田和由
- Journal Title
  
  医学のあゆみ 227
  
  Pages: 347-351
- Data Source
  KAKENHI-PROJECT-20590494
[Journal Article] Combination antibody-based cancer immunotherapy2007
- Author(s)
  Takeda K
- Journal Title
  
  CANCER SCIENCE 98
  
  Pages: 1297-1302
- NAID
  10019998008
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Combinaion antibody-based cancer immunotherapy2007
- Author(s)
  Takeda K
- Journal Title
  
  CANCER SCIENCE 98
  
  Pages: 1297-1302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Targeting death-inducing receptors in cancer therapy2007
- Author(s)
  Takeda, K., J., Stagg, H., Yagita, K., Okumura, M. J., Smyth
- Journal Title
  
  Oncogene 26
  
  Pages: 3745-3757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Interleukin-12- and interferon-gamma-mediated natural killer cell activation by Agaricus blazei Murill2007
- Author(s)
  Yuminamochi, E., T., Koike, K., Takeda, I., Horiuchi, K., Okumura
- Journal Title
  
  Immunology 121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Combination antibody-based cancer immunotherapy2007
- Author(s)
  Takeda, K., K., Okumura, M. J., Smyth
- Journal Title
  
  Cancer science 98
  
  Pages: 1297-1302
- NAID
  10019998008
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Effects of a fermented milk drink containing Lactobacillus casei strain shirota on the human NK-cell activity2007
- Author(s)
  Takeda K
- Journal Title
  
  JOURNAL OF NUTRITION 137
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Targeting death-inducing receptors in cancer therapy2007
- Author(s)
  Takeda K
- Journal Title
  
  ONCOGENE 26
  
  Pages: 3745-3757
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity2007
- Author(s)
  Takeda, K., K., Okumura
- Journal Title
  
  The Journal of nutrition 137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] 2006. Eradication of established tumors in mice by a combination antibody-based therapy2006
- Author(s)
  Uno, T., K., Takeda, Y., Kojima, H., Yoshizawa, H., Akiba, R. S., Mittler, F., Gejyo, K., Okumura, H., Yagita, M. J., Smyth
- Journal Title
  
  Nature medicine 12
  
  Pages: 693-698
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Application of immunoreaction enhancer solutions to an enzyme-linked immunosorbent assay for antigen-specific IgE in mice immunized with recombinant major mite allergens or ovalbumin2006
- Author(s)
  Kikuchi, Y., T., Takai, M., Ota, T., Kato, K., Takeda, K., Mitsuishi, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  International archives of allergy and immunology 141
  
  Pages: 322-330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.2005
- Author(s)
  Ota, T., K.Takeda, H.Akiba, Y.Hayakawa, K.Ogasawara, Y.Ikarashi, S.Miyake, H.Wakasugi, T.Yamamura, M.Kronenberg, D.H.Raulet, K.Kinoshita, H.Yagita, M.J.Smyth, K.Okumura
- Journal Title
  
  Blood 106
  
  Pages: 184-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Critical contribution of CD8O and CD86 to induction of anterior chamber-associated immune deviation.2005
- Author(s)
  Tsukahara, R., M.Takeuchi, H.Akiba, T.Kezuka, K.Takeda, Y.Usui, M.Usui, H.Yagita, K.Okumura
- Journal Title
  
  Int Immunol 17
  
  Pages: 523-530
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL identified immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  Bood (in press)
- Data Source
  KAKENHI-PROJECT-16590411
[Journal Article] 2005.TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage.2005
- Author(s)
  Kaduka, Y., K.Takeda, M.Nakayama, K.Kinoshita, H.Yagita, K.Okumura
- Journal Title
  
  Biochem Biophys Res Commun 331
  
  Pages: 384-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL identified immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  Bood (in press)
- Data Source
  KAKENHI-PROJECT-16017292
[Journal Article] TRAIL identified immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  Bood (in press)
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL identified immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  Bood (in press)
- Data Source
  KAKENHI-PROJECT-16023266
[Journal Article] ICOS costimulates invariant NKT cell activation.2005
- Author(s)
  Kaneda, H., K.Takeda, T.Ota, Y.Kaduka, H.Akiba, Y.Ikarashi, H.Wakasugi, M.Kronenberg, K.Kinoshita, H.Yagita, K.Okumura
- Journal Title
  
  Biochem Biophys Res Commun 327
  
  Pages: 201-207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Takeda, K., E.Cretney, Y.Hayakawa, T.Ota, H.Akiba, K.Ogasawara, H.Yagita, K.Kinoshita, K.Okumura, M.J.Smyth
- Journal Title
  
  Blood 105
  
  Pages: 2082-2089
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Beta2-microglobulin required for cell surface expression of blastocyst MHC.2005
- Author(s)
  Takeda, K. et al.
- Journal Title
  
  Biochem Biophys Res Commun 332
  
  Pages: 311-317
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Takeda, K. et al.
- Journal Title
  
  Blood 105
  
  Pages: 2082-2089
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo.2005
- Author(s)
  Akiba, H., K.Takeda, Y.Kojima, Y.Usui, N.Harada, T.Yamazaki, J.Ma, K.Tezuka, H.Yagita, K.Okumura
- Journal Title
  
  J Immunol 175
  
  Pages: 2340-2348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL identified immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Kazuyoshi Takeda, et al.
- Journal Title
  
  Bood 105・5
  
  Pages: 2082-2089
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590411
[Journal Article] CAM and NK cells2004
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  eCAM 1・1
  
  Pages: 17-27
- Data Source
  KAKENHI-PROJECT-16023266
[Journal Article] Induction of Tumor-specific T Cell Immunity by Anti-DR5 Antibody Therapy.2004
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  J.Exp.Med. 199・4
  
  Pages: 437-448
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] CAM and NK cells2004
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  eCAM 1・1
  
  Pages: 17-27
- Data Source
  KAKENHI-PROJECT-16590411
[Journal Article] CAM and NK cells2004
- Author(s)
  Kazuyoshi Takeda, et al.
- Journal Title
  
  eCAM 1・1
  
  Pages: 17-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590411
[Journal Article] Induction of Tumor-specific T Cell Immunity by Anti-DR5 Antibody Therapy.2004
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  J.Exp.Med. 199・4
  
  Pages: 437-448
- Data Source
  KAKENHI-PROJECT-16590411
[Journal Article] Contribution of CD1d-unrestricted hepatic DX5+ NKT cells to liver injury in Plasmodium berghei-parasitized erythrocyte-injected mice.2004
- Author(s)
  Adachi, K., H.Tsutsui, E.Seki, H.Nakano, K.Takeda, K.Okumura, L.Van Kaer, K.Nakanishi
- Journal Title
  
  Int Immunol 16
  
  Pages: 787-798
- NAID
  10013085831
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] CAM and NK Cells.2004
- Author(s)
  Takeda, K., K.Okumura
- Journal Title
  
  Evid Based Complement Alternat Med 1
  
  Pages: 17-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Induction of Tumor-specific T Cell Immunity by Anti-DR5 Antibody Therapy.2004
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  J.Exp.Med. 199・4
  
  Pages: 437-448
- Data Source
  KAKENHI-PROJECT-16023266
[Journal Article] CAM and NK cells2004
- Author(s)
  Takeda Kazuyoshi
- Journal Title
  
  eCAM 1・1
  
  Pages: 17-27
- Data Source
  KAKENHI-PROJECT-16017292
[Journal Article] Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.2004
- Author(s)
  Takeda, K. et al.
- Journal Title
  
  J Exp Med 199
  
  Pages: 437-448
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] CAM and NK Cells.2004
- Author(s)
  Takeda, K. et al.
- Journal Title
  
  Evid Based Complement Alternat Med 1
  
  Pages: 17-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL and its receptors as targets for cancer therapy.2004
- Author(s)
  Yagita, H., K.Takeda, Y.Hayakawa, M.J.Smyth, K.Okumura
- Journal Title
  
  Cancer Sci 95
  
  Pages: 777-783
- NAID
  10014170265
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.2004
- Author(s)
  Takeda, K., N.Yamaguchi, H.Akiba, Y.Kojima, Y.Hayakawa, J.E.Tanner, T.J.Sayers, N.Seki, K.Okumura, H.Yagita, M.J.Smyth
- Journal Title
  
  J Exp Med 199
  
  Pages: 437-448
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Induction of tumor-specific T Cell immunity by anti-DR5 antibody therapy.2004
- Author(s)
  Kazuyoshi Takeda, et al.
- Journal Title
  
  J.Exp.Med. 199・4
  
  Pages: 437-448
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590411
[Presentation] Mobilization and Fcγ-Receptor Expression of Six Cell Subsets, During and After Acute Exercise. American College of Sports Medicine2019
- Author(s)
  鈴井正敏、竹田和由、Shek, P. N.、Shephard, R. J.、奥村康
- Organizer
  the 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02695
[Presentation] Importin β1 inhibition augments anticancer effect of anti-DR5 agonistic antibody in TRAIL resistant tumor cells.2019
- Author(s)
  小島裕子、仁科隆史、中野裕康、奧村康、竹田和由
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19483
[Presentation] Mobilization and Fcg-Receptor Expression of Six Cell Subsets, During and After Acute Exercise. American College of Sports Medicine2019
- Author(s)
  鈴井正敏、竹田和由、Shek, P. N.、Shephard, R. J.、奥村康
- Organizer
  American College of Sports Medicine the 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19483
[Presentation] CAF-induced partial epithelial-mesenchymal transition mediated formation of metastatic human breast cancer clusters.2019
- Author(s)
  折茂彰、伊藤恭彦、目澤義弘、醍醐弥太郎、樋野興夫、竹田和由、浜田道昭、松村優子
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19483
[Presentation] Importin β1 inhibition augments anticancer effect of anti-DR5 agonistic antibody in TRAIL resistant tumor cells.2019
- Author(s)
  小島裕子、仁科隆史、中野裕康、奧村康、竹田和由
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02695
[Presentation] CAF-induced partial epithelial-mesenchymal transition mediated formation of metastatic human breast cancer clusters.2019
- Author(s)
  折茂彰、伊藤恭彦、目澤義弘、醍醐弥太郎、樋野興夫、竹田和由、浜田道昭、松村優子
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02695
[Presentation] CAFs induce formation of metastatic human breast tumor cell clusters with partial epithelial-mesenchymal transition2018
- Author(s)
  折茂彰、伊藤恭彦、目澤義弘、Kaidiliavi Sulidan、醍醐弥太郎、Nadia Wali、樋野興夫、竹田和由、浜田道昭、松村優子
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19483
[Presentation] 大腸癌モデルにおいてL.bulgaricus OLL1073R-1の菌体外多糖がもたらすCTLA-4阻害治療の効果増強と腫瘍浸潤T細胞解析2018
- Author(s)
  川鍋（松田）啓誠、中村真梨枝、竹田和由、狩野宏、奥村康
- Organizer
  第32回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18H02695
[Presentation] CAFs induce formation of metastatic human breast tumor cell clusters with partial epithelial-mesenchymal transition2018
- Author(s)
  折茂彰、伊藤恭彦、目澤義弘、Kaidiliavi Sulidan、醍醐弥太郎、Nadia Wali、樋野興夫、竹田和由、浜田道昭、松村優子
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02695
[Presentation] Activation of Src signaling mediates carcinoma-associated fibroblast-promoted metastasis in human breast cancers2018
- Author(s)
  伊藤恭彦、松村優子、目澤義弘、ソリタン　カディア、ワリ　ナディラ、寺尾保久、竹田省、奥村康、竹田和由、樋野興夫、折茂彰
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02695
[Presentation] 大腸癌モデルにおいてL.bulgaricus OLL1073R-1の菌体外多糖がもたらすCTLA-4阻害治療の効果増強と腫瘍浸潤T細胞解析2018
- Author(s)
  川鍋（松田）啓誠、中村真梨枝、竹田和由、狩野宏、奥村康
- Organizer
  第32回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K19483
[Presentation] Activation of Src signaling mediates carcinoma-associated fibroblast-promoted metastasis in human breast cancers2018
- Author(s)
  伊藤恭彦、松村優子、目澤義弘、ソリタン　カディア、ワリ　ナディラ、寺尾保久、竹田省、奥村康、竹田和由、樋野興夫、折茂彰
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19483
[Presentation] Carcinoma-associated fibroblasts raise highly aggressive cancer cells via metastasis-promoting autocrine signaling2015
- Author(s)
  Matsumura, Y., Ito, Y., Wali, N., Ito, T, Mogushi, K., Terao, Y., Takeda, S., Okumura, K., Takeda, K., Hino, O., Orimo, A.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Presentation] Most of the CD8+ TIL are tumor reactive in spontaneously regressing or progressing murine gastric cancer2015
- Author(s)
  Nagaoka, K., Hosoi, A., Matsushita, H., Kubo, M., Takeda, K., Kakimi, K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Presentation] IFN-γ produced by cytotoxic T cells immunoedits the cancer genome2015
- Author(s)
  Takeda, K.
- Organizer
  International conference of cancer immunotherapy and macrophage 2015
- Place of Presentation
  東京都文京区
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14410
[Presentation] Chemokine CXCL14 is a multistep tumor suppressor.2015
- Author(s)
  Ryu-Ichiro Hata, Kazuhito Izukuri, Yasumasa Kato, Soichiro Sasaki, Chihiro Miyamoto, Tetsu Akasaka, Xiaoyan Yang, Yojiro Maehata, Yoji Nagashima, Kazuyoshi Takeda, Tohru Kiyono, Naofumi Mukaida, Masaru Taniguchi
- Organizer
  2015 American Association of Cancer Research Annual Meeting
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293384
[Presentation] Expression of chemokine BRAK/CXCL14 suppresses tumor growth and metastasis NK cell dependently and increases survival rate of tumor-bearing mice.2013
- Author(s)
  Hata R, Izukuri K, Kato Y, Takeda K, Kiyono T, Mukaida N, Taniguchi M
- Organizer
  9th AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui, Hawaii
- Data Source
  KAKENHI-PROJECT-24659843
[Presentation] Role of Neogenin n GD3- expressing human melanoma cells.癌内線維芽細胞の近傍のヒト乳がん細胞に転移能を授ける2013
- Author(s)
  折茂彰、伊藤恭彦、竹田和由、奥村康、樋野興夫、堀本義哉
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300355
[Presentation] 4) Pulripotents stem cell-derived myeloid cells engineered to express TRAIL as a possible cell medicine for cancer.2013
- Author(s)
  MAKI Hiroyuki,UEMURA Yasushi, AHANG Rong, LIU Tianyi, SUZUKI Motoharu, HIROSAW Natsumi, TAKEDA Kazuyoshi, SAKAMOTO Yasushi, SENJU Satoru, KUZUSHIMA Kiyotaka
- Organizer
  第42回日本免疫学会学術総会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23300355
[Presentation] 2) A phase 1 clinical trial with KIF20A peptide in combination with gemcitabine for advanced pancreatic cancer patients.切除不能・進行膵癌に対する新規膵癌ペプチドワクチンとゲムシタビン塩酸塩を用いた第1相試験2013
- Author(s)
  鈴木伸明、硲彰一、上野富雄、吉野茂文、竹田和由、中村祐輔、岡正朗
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300355
[Presentation] 3) Pulripotents stem cell-derived myeloid cells engineered to express TRAIL as a possible cell medicine for cancer. TRAILを発現する多機能幹細胞由来ミエロイド細胞を用いた細胞医薬の開発2013
- Author(s)
  牧寛之、植村靖史、張エイ、竹田和由、劉天懿、鈴木元晴、都築忍、岡村文子、赤塚美樹、西村泰治、千住覚、葛島清隆
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23300355
[Presentation] Expression of chemokine BRAK/CXCL14 suppresses tumor growth and metastasis NK cell dependently and increases survival rate of tumor-bearing mice2013
- Author(s)
  Hata R, Izukuri K, Kato Y, Takeda K, Kiyono T, Mukaida N, Taniguchi M
- Organizer
  9^<th> AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24659843
[Presentation] NK cells are indispensable for suppression of tumor growth and metastasis in transgenic mice over-expressing chemokine CXCL14/BRAK.2012
- Author(s)
  Hata R, Izukuri K, Kato Y, Takeda K, Kiyono T, Mukaida N, Taniguchi M
- Organizer
  American Association for Cancer Research Annual Meeting 2012
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24659843
[Presentation] Expression of CXCL14/BRAK suppresses tumor growth and metastasis and prolongs the life span of tumor-burden mice.2012
- Author(s)
  Hata R, Kato Y, Takeda K, Kiyono T, Mukaida N, Taniguchi M
- Organizer
  71st Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Sapporo, 2012
- Data Source
  KAKENHI-PROJECT-24659843
[Presentation] Expression of CXCL14/BRAK suppresses tumor growth and metastasis and prolongs the life span of tumor-burden mice2012
- Author(s)
  Hata R, Kato Y, Takeda K, Kiyono T, Mukaida N, Taniguchi M
- Organizer
  71^<st> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-24659843
[Presentation] NK cells are indispensable for suppression of tumor growth and metastasis in transgenic mice over-expressing chemokine CXCL14/BRAK2012
- Author(s)
  Hata R, Izukuri K, Kato Y, Takeda K, Kiyono T, Mukaida N, Taniguchi M
- Organizer
  American Association for Cancer Research Annual Meeting 2012
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24659843
[Presentation] Innate immune responses involving NK and NKT cells promote liver regeneration after partial hepatectomy2011
- Author(s)
  Hosoya S, Ikejima K, Arai K, Kon K, Yamashina S, Takeda K, Watanabe S
- Organizer
  Poster Session(Poster of Distinction), The Liver Meeting 2011(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Mice depleting natural killer T cells are more susceptible to dietary-induced steatohepatitis, Selected Oral Presentation 102011
- Author(s)
  Ikejima K, Yamagata H, Arai K, Ishikawa S, Hosoya S, Kon K, Yamashina S, Suzuki S, Takeda K, Watanabe S
- Organizer
  18th International Symposium on Cells of the Hepatic Sinusoid(Biannual Meeting of International Society for Hepatic Sinusoidal Research)
- Place of Presentation
  Florence, Italy
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Imaired liver regeneration after partial hepatectomy in mice depleting NK and NKT cells2011
- Author(s)
  Hosoya S, Ikejima K, Arai K, Aoyama T, Kon K, Ishikawa S, Yamagata H, Yamashina S, Suzuki S, Takeda K, Watanabe S
- Organizer
  Poster Session, 18th International Symposium on Cells of the Hepa Sin usoid(Biannual Meeting of International Society for Hepatic Sinusoidal Research)
- Place of Presentation
  Florence, Italy
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Impaired hepatic innate responses involving NKT cells in obese diabetic KK-Ay mice2010
- Author(s)
  Yamagata H, Ikejima K, Ishikawa S, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Organizer
  Poster Session I Steatohepatitis-NASH, 15^<th> Int ernational Symposium on Cells of International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Pasadena, CA, USA
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] CD1d-restricted natural killer T cells modulate susceptibility to dietary-induced steatohepatitis in mice2010
- Author(s)
  Ikejima K, Yamagata H, Ishikawa S, Arai K, Aoyama T, Kon K, Takeda K, Watanabe S
- Organizer
  Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Contribution of CD1d-restricted natural killer T cells to xenobiotics-induced hepatic inflammation and fibrogenesis in mice2010
- Author(s)
  Ikejima K, Ishikawa S, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Organizer
  Session II. Steatohepatitis-II(Oral presentation), 15th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Pasadena, CA, USA
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Tim-3 mediates phagocytosis of apoptotic cells by inflammatory macrophage and CD8^+ dendritic cell subsets.2010
- Author(s)
  Takeda K., et al.
- Organizer
  第18回マクロファージ分子細胞生物学国際シンポジウム
- Place of Presentation
  熊本県熊本市
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation] CD1d-restricted natural killer T cells contribute to thioacetamide-induced he inf lammation and fibrogenesis in mice2010
- Author(s)
  Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Organizer
  Parallel Session 11 : Chronic liver injury and fibrosis, The 45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Tim-3 mediates phagocytosis of apoptotic cells by inflammatory macrophage and CD8^+ dendritic cell subsets2010
- Author(s)
  Takeda, K., et al.
- Organizer
  第18回マクロファージ分子細胞生物学国際シンポジウム
- Place of Presentation
  くまもと県民交流館パレア熊本市、熊本県
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation] Contribution of NK and NKT cells in hepatic regeneration after partial hepatectomy in mice2010
- Author(s)
  Hosoya S, Ikejima K, Aoyama T, Ishikawa S, Yamagata H, Kon K, Takeda K, Watanabe S
- Organizer
  Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.2010
- Author(s)
  Takeda K., et al.
- Organizer
  第14回国際免疫学会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation] Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.2010
- Author(s)
  Takeda, K., et al.
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸国際展示場神戸市、兵庫県
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation] Depletion of natural killer T cells increases the susceptibility to dietary-induced steatohepatitis in mice2010
- Author(s)
  Ikejima K, Yamagata H, Arai K, Ishikawa S, Hosoya S, Kon K, Yamashina S, Takeda K, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Hepatic NKT and NK cells regulate liver reg hep atectomy in mice2010
- Author(s)
  Hosoya S, Ikejima K, Aoyama T, Ishikawa S, Yamagata H, Kon K, Yamashina S, Takeda K, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Obese diabetic KK-Ay mice are resistant to NKT cell-mediated liver injury induced by a-galactosylceramide2009
- Author(s)
  Ikejima K, Yamagata H, Takeda K, Aoyama T, Kon K, Yamashina S, Suzuki S, Watanabe S
- Organizer
  Poster S The 44th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Pioglitazone improves abnormal expression of hepatic NKT cells in obese and diabetic KK-Ay mice2009
- Author(s)
  Ikejima K, Yamagata H, Takeda K, Kon K, Aoyama T, Yamashina S, Watanabe S
- Organizer
  Poster session Conference on NAFLD/NASH and related metabolic disease
- Place of Presentation
  Bologna, Italy
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Pioglitazone restores expression and function of hepatic NKT cells in obese and diabetic KK-Ay mice2009
- Author(s)
  Yamagata H, Ikejima K, Takeda K, Aoyama T, Kon K, Yamashina S, Watanabe S
- Organizer
  Poster Session, The 44 meeting of the European Association for the Study of the Liver
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Induction of primary sclerosing cholangiocites-like disease by DR5-medited apoptosis2009
- Author(s)
  Takeda, K.
- Organizer
  12^<th> International TNF conference
- Place of Presentation
  Madrid, Spain
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-20060022
[Presentation] Induction of primarysclerosing cholangiocites-like disease by DR5-medited apoptosis2009
- Author(s)
  Takeda K., et al.
- Organizer
  12th International TNF conference
- Place of Presentation
  Madrid, Spain
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation] Pioglitazone prevents apoptosis of hepatic NKT cells in obese and diabetic KK-Ay mice2009
- Author(s)
  Yamagata H, Ikejima K, Takeda K, Kon K, Aoyama T, Yamashina S, Watanabe S
- Organizer
  Poster Session,(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Thioacetamide-induced hepatic fibrogenesis is ameliorated in mice genetically disruptive of CD1d2009
- Author(s)
  Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Takeda K, Watanabe S
- Organizer
  Poster Session,(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Induction of primary sclerosing cholangiocites-like disease by DR5-medited apoptosis2009
- Author(s)
  Takeda, K.
- Organizer
  12^<th> International TNF conference
- Place of Presentation
  Madrid, Spain
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation] TRAIL : from immunosurveillance to immunotherapy2008
- Author(s)
  竹田和由
- Organizer
  International Workshop Immunotherapy-2008 Implementing Combinations
- Place of Presentation
  Parco Hotel Havana, Cuba
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-20060022
[Presentation] TRAIL : from immunosurveillance to immunotherapy2008
- Author(s)
  Takeda K., et al.
- Organizer
  International Workshop Immunotherapy-2008
- Place of Presentation
  Havana, Cuba
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation] TRATL : from immunosurveil lance to immunotherapy2008
- Author(s)
  竹田和由
- Organizer
  International Workshop Immunotherapy-2008Implementing Combinations
- Place of Presentation
  Parco Hotel Havana, Cuba
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-20590494
[Presentation]2008
- Author(s)
  Takeda K, Kojima Y, Yagita H, Smyth MJ, Okumura K
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19590257
[Presentation]2008
- Author(s)
  Kojima Y, Takeda K, Yagita H, Smyth MJ, Okumura K
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19590257
[Presentation] Combined NKT cell-based immunotherapy eradicates established tumors in mice2007
- Author(s)
  Takeda Kazuyoshi
- Organizer
  第37回日本免疫学会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Presentation] Combined NKT cell-based immunotherapy eradicates established tumors in mice2007
- Author(s)
  Takeda, Kazuyoshi
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Grand Prince Hotel New Takanawa
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Presentation] Combined NKT cell-based immunotherapy eradicates established tumors inmice2007
- Author(s)
  Takeda Kazuyoshi
- Organizer
  第37回日本免疫学会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-18390292

1. NAKANO Hiroyasu (70276476)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
2. AKIBA Hisaya (60338316)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. NAKAYAMA Katsufumi (20453582)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. YAGITA Hideo (30182306)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
5. OKUMURA Ko (50009700)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
6. MAEHATA Yojiro (80410009)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. IKEJIMA Kenichi (20317382)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
8. YAMASHINA Shunhei (30338412)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
9. KON Kazyyoshi (30398672)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
10. HATA Ryu-Ichiro (10014276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
11. IZUKURI Kazuhito (90257296)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
12. EBATA Tomohiko (30343487)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KOJIMA Yuko (60231312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. SUZUKI Ryuji (70373470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. AKASAKA TETSU (60316263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. MIYAMOTO CHIHIRO (50633963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. MUKAIDA NAOFUMI (30182067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 安保徹 (30005079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 渡部久実 (50143756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 関川弘雄 (50018694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HARADA Kenichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. MOGUSHI Kaoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. TAKANO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. BABA Tomohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. IKEDA Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. OSUGI Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. HASEGAWA Takeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 田原秀晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 佐藤まりも

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 入村達郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
31. 早川芳弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
32. 垣見和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 松下博和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 恒富亮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 角田卓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. ワリナディラ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 折茂彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 醍醐弥太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 平賀徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 伊藤匠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 浜田道昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 傅田香里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 済木育夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 高橋淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 中本安成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 佐々木宗一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 飯沼久恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 福島亮治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 小笠原康悦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 鈴木弘行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 後藤満一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 高井俊行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 谷口克

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 加藤靖正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 長嶋洋治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKEDA KAZUYOSHI 竹田 和由

TAKEDA Kazuyoshi 竹田 和由

竹田 和由 タケダ カズヨシ

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癌と免疫の相互作用による癌細胞の変異と免疫抑制能獲得機構の解析Principal InvestigatorOngoing

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Analysis of cancer microenvironment under the growth control by anti-tumor immune responsePrincipal Investigator

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Analysis of molecular mechanisms underlying acquired resistance of tumor cells responding to anti-tumor immunityPrincipal InvestigatorOngoing

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Analysis of B cell receptors expressed on tumor infiltrating B cells by next generation sequencingPrincipal Investigator

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がん微小環境により癌が免疫耐性を新規に獲得する機構の解析Principal Investigator

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Analysis of tumor-rejecting biological reactions induced by tumor specific immune responsesPrincipal Investigator

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免疫による癌拒絶局所での分子機構の解析Principal Investigator

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Development of novel cancer therapy by combination of immune activation with tumor apoptosis inductionPrincipal Investigator

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TAKEDA KAZUYOSHI 竹田和由

TAKEDA Kazuyoshi 竹田和由

竹田和由タケダカズヨシ