SASAKI TAKEHIKO 佐々木雄彦

… Alternative Names

Researcher Number	50333365
Other IDs
External Links
Affiliation (Current)	2020: 東京医科歯科大学, 難治疾患研究所, 教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 東京医科歯科大学, 難治疾患研究所, 教授 2017 – 2018: 秋田大学, 医学(系)研究科(研究院), 非常勤講師 2014 – 2017: 秋田大学, 医学(系)研究科(研究院), 教授 2015 – 2016: 秋田大学, 医学系研究科, 教授 2011: Akita University, 医学(系)研究科(研究院), 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Biological pharmacy / General medical chemistry / Cell biology / Cell biology / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 48040:Medical biochemistry-related Except Principal Investigator Biological Sciences / Emergency medicine / Pathological medical chemistry … More
Keywords	Principal Investigator イノシトールリン脂質 / リン脂質 / シグナル伝達 / 脂質 / 細胞走化性 / 遺伝子改変マウス / 炎症 / 病態モデル / 細胞増殖 / PI3-kinase … More Except Principal Investigator イノシトールリン脂質 / リン脂質 / 脂質 / 集中治療 / 呼吸不全 / ウイルス感染症 / 細胞膜イノシトールリン脂質 / インフルエンザ / 急性呼吸不全 / ERK / NGF / 神経科学 / 脳神経疾患 / 癌抑制遺伝子 / PICT1 / PTEN / ホスホイノシタイド / 細胞内情報伝達 / 脂質結合蛋白質 / 膜変形作用 / 細胞膜 / イメージング / Phosphoinositide / Lipid binding domain / Coronin1A / PI(4.5)P2 / Actin filaments / 可視化 / PI(3, 4)P2 / 浸潤突起 / FISH / 膜変形 / PI(3,4,5)P3 / N-WASP / アクチン / 情報伝達 / 脂質結合ドメイン / 肝臓学 / 肝腫瘍性病変 / 肝癌 / Akt2 / PPARγ / INPP4B / Pten / 脂肪性肝炎 / ホスホリパーゼD / 神経軸策 / PC12細胞 / 小脳果顆粒細胞 / 神経接着分子 / シグナル伝達 / 小脳顆粒細胞 / 軸索伸長 / 神経細胞接着分子 / 一級アルコール / Phospholipase D / Neurite / PC 12 cells / Cerebellar granule cells / Neuronal adhesion molecule / Signal transduction / 領域マネジメント / 研究支援センター / 領域事務局 / 脂質データベース / 広報活動 / 領域会議の開催 / 前立腺癌 / 腎細胞癌 / 高脂肪食 / 肥満 / palmitic acid / fatty acid synthase / MIC-1 / 腎癌 / パルミチン酸 / 脂肪酸合成酵素 / AMPK / PI3K / miRNA / Fatty acid symthetase / 脱リン酸化酵素 / ホスファターゼ / フォスファターゼ / オートファジー / 脂質分解 / リピドーム解析 / 液胞/リソソーム / リパーゼ / オートファジックボディ / Atg15 / 代謝 / ヒトパピローマウイルス / ホスホイノシチド / 子宮頸がん Less

ホスホイノシタイド分子種の多様性と機能の解明Principal InvestigatorOngoing
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tokyo Medical and Dental University
ホスホイノシチド動態制御を介したヒトパピローマウイルス潜伏感染機構の解明Ongoing
- Principal Investigator
  
  柊元巌
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  National Institute of Infectious Diseases
分泌型膜リン脂質の生物活性の発見Principal InvestigatorOngoing
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Tokyo Medical and Dental University
脂質からみたオートファジーの膜動態Ongoing
- Principal Investigator
  
  堀江朋子 (川俣朋子)
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Institute of Technology
新規生体脂質の代謝機構と機能の解明Principal InvestigatorOngoing
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Medical and Dental University
  Akita University
膜リン脂質クオリティ分析技術の開発と生命現象への適用Principal InvestigatorOngoing
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
  Akita University
Development of a mouse model of microscopic polyangiitisPrincipal Investigator
- Principal Investigator
  
  Sasaki Takehiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Akita University
「リポクオリティ」領域研究の推進Ongoing
- Principal Investigator
  
  有田誠
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
Metabolism and functions of novel phospholipidsPrincipal Investigator
- Principal Investigator
  
  Sasaki Takehiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Akita University
The identification of intact PI3P phosphatase and physiological role
- Principal Investigator
  
  EGUCHI SATOSHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Akita University
Molecular analysis and target exploration underlying progression of urologic cancers associated with obesity
- Principal Investigator
  
  HABUCHI Tomonori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Akita University
脂肪性肝炎と炎症性腸疾患の進展に寄与する脂質メディエーターの同定Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
Elucidation of the phosphatidylinositol metabolism to control steatohepatitis and hepatocellular carcinoma
- Principal Investigator
  
  HORIE Yasuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
脂質脱リン酸化酵素阻害によるリソソーム機能賦活・長寿モデルマウスの開発Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Akita University
ホスファチジルイノシトールリン酸生成酵素による生体機能調節Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Akita University
細胞増殖・死の制御と癌の悪性化におけるクラスIIIPI3キナーゼの役割Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
Role of phospholipids in the pathogenesis of respiratory failure mediated by highly pathogenic influenza virus infection
- Principal Investigator
  
  IMAI Yumiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Emergency medicine
  General pharmacology
- Research Institution
  Akita University
Role of phosphatidylinositols in the pathogenesis of severe respiratory failure
- Principal Investigator
  
  IMAI Yumiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Akita University
新規リン脂質代謝酵素欠損マウスでの著明な小胞輸送異常と病態Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
リン脂質により制御される標的分子の効率的探索法の開発と応用Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Akita University
Physiological roles of phosphatidylinositol bisphosphatesPrincipal Investigator
- Principal Investigator
  
  SASAKI Takehiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Akita University
Spatial and temporal regulation of signalling molecules by phosphoinositides
- Principal Investigator
  
  TAKENAWA Tadaomi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kobe University
  The University of Tokyo
脂質代謝異常による不随意運動の発現メカニズムPrincipal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
イノシトールリン脂質代謝異常に起因する運動異常モデルマウスの解析
- Principal Investigator
  
  佐々木純子
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
新規癌抑制候補遺伝子による発癌制御の検討
- Principal Investigator
  
  鈴木聡
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
イノシトールリン脂質を作用点とした感染応答の制御Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
がん抑制遺伝子産物PTENとホスホイノシチドによる細胞運動制御機構の解明Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
イノシトールリン脂質代謝酵素欠損による免疫不全症とメンブレントラフィック異常Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
細胞運動制御におけるがん抑制遺伝子産物PTENとホスホイノシチドの機能解析Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
ホスホイノシチド可視化マウスと遺伝子欠損マウスを用いた細胞遊走制御機構の解析Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Akita University
新規癌抑制タンパク質p110γによる細胞癌化抑制メカニズムの解明Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
STUDY ON FUNCTION OF PHOSPHOLIPASE D2 IN NEURITE REMODELING
- Principal Investigator
  
  KANAHO Yasunori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH
新規癌抑制タンパク質p110γによる細胞癌化抑制メカニズムの解明Principal Investigator
- Principal Investigator
  
  佐々木雄彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Mechanism of p110γ-mediated growth suppressionPrincipal Investigator
- Principal Investigator
  
  SASAKI Takehiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science

[Book] 脂質代謝異常と関連疾患（下巻）2015
- Author(s)
  佐々木雄彦
- Total Pages
  413
- Publisher
  エル・アイ・シー社
- Data Source
  KAKENHI-PROJECT-15K14947
[Book] 脂質代謝異常と関連疾患2015
- Author(s)
  佐々木雄彦
- Total Pages
  2
- Publisher
  エル・アイ・シー社
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Book] 脂質代謝異常と関連疾患（上巻）2015
- Author(s)
  佐々木雄彦（編集）
- Total Pages
  413
- Publisher
  （株）エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-26253006
[Book] 脂質代謝異常と関連疾患（下巻）2015
- Author(s)
  佐々木雄彦（編集）
- Total Pages
  477
- Publisher
  （株）エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-26253006
[Book] 脂質代謝異常と関連疾患2015
- Author(s)
  高須賀俊輔、佐々木雄彦
- Total Pages
  11
- Publisher
  エル・アイ・シー社
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Book] 分子から個体へと深化する脂質生物学2010
- Author(s)
  佐々木雄彦、横溝岳彦、竹縄忠臣
- Total Pages
  237
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21689003
[Book] 分子から個体へと深化する脂質生物学2010
- Author(s)
  佐々木雄彦、横溝岳彦、竹縄忠臣
- Total Pages
  237
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21659067
[Book] PtdIns(3, 4, 5)P3代謝酵素による好中球遊走の制御経路の役割2007
- Author(s)
  西尾美希・鈴木聡・佐々木雄彦
- Total Pages
  2
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-18689003
[Book] PtdIns(3, 4, 5)P3代謝酵素による好中球遊走の制御経路の役割.2007
- Author(s)
  西尾美希、鈴木聡、佐々木雄彦
- Total Pages
  115
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-18659073
[Book] PtdIns(3, 4, 5)P3代謝酵素による好中球遊走の制御経路の役割2007
- Author(s)
  西尾美希・鈴木聡・佐々木雄彦
- Total Pages
  2
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-18050004
[Book] 形と運動を司る細胞のタイナミクス脂質結合モジュールによるイノシトールリン脂質動態解析2006
- Author(s)
  佐々木雄彦
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18659073
[Book] 再生医療のための分子生物学2006
- Author(s)
  佐々木雄彦ら
- Total Pages
  250
- Publisher
  幹細胞のシグナル伝達〜PI3/Akt〜
- Data Source
  KAKENHI-PROJECT-17659089
[Book] 形と運動を司る細胞のダイチミクス脂質結合モジュールによるイノシトールリン脂質動態解析2006
- Author(s)
  佐々木雄彦
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18050004
[Book] 形と運動を司る細胞のダイナミクス脂質結合モジュールによるイノシトールリン脂質動態解析2006
- Author(s)
  佐々木雄彦
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18689003
[Book] 再生医療のための分子生物学2005
- Author(s)
  佐々木雄彦
- Total Pages
  246
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-16044204
[Book] 再生医療のための分子生物学2005
- Author(s)
  佐々木雄彦
- Total Pages
  246
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-15687007
[Book] 再生医療のための分子生物学2005
- Author(s)
  佐々木雄彦
- Total Pages
  246
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-16017213
[Book] 再生医療のための分子生物学2005
- Author(s)
  佐々木雄彦
- Total Pages
  246
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-17025006
[Book] 再生医療のための分子生物学2005
- Author(s)
  佐々木雄彦
- Total Pages
  246
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-17024005
[Journal Article] Lysophosphatidylinositol‐acyltransferase‐1 is involved in cytosolic Ca 2+ oscillations in macrophages2019
- Author(s)
  Takemasu Shinya、Ito Masaki、Morioka Shin、Nigorikawa Kiyomi、Kofuji Satoshi、Takasuga Shunsuke、Eguchi Satoshi、Nakanishi Hiroki、Matsuoka Isao、Sasaki Junko、Sasaki Takehiko、Hazeki Kaoru
- Journal Title
  
  Genes to Cells
  
  Volume: - Pages: 1-11
- DOI
  10.1111/gtc.12681
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07194, KAKENHI-PROJECT-18K07233, KAKENHI-ORGANIZER-15H05897, KAKENHI-PUBLICLY-18H04877, KAKENHI-PROJECT-17K19375
[Journal Article] Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency.2019
- Author(s)
  Nishio Miki、Miyachi Yousuke、Otani Junji、Tane Shoji、Omori Hirofumi、Ueda Fumihito、Togashi Hideru、Sasaki Takehiko、Mak Tak Wah、Nakao Kazuwa、Fujita Yasuyuki、Nishina Hiroshi、Maehama Tomohiko、Suzuki Akira
- Journal Title
  
  FASEB J
  
  Volume: 33 Pages: 5548-5560
- DOI
  10.1096/fj.201802005r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06132, KAKENHI-PROJECT-18K06219, KAKENHI-PROJECT-18K15211, KAKENHI-ORGANIZER-15H05897, KAKENHI-PUBLICLY-18H04764, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-16K08626
[Journal Article] Alveolar Macrophages Drive Hepatocellular Carcinoma Lung Metastasis by Generating Leukotriene B42018
- Author(s)
  Nosaka T, Baba T, Tanabe Y, Sasaki S, Nishimura T, Imamura Y, Yurino H, Hashimoto S, Arita M, Nakamoto Y, Mukaida N.
- Journal Title
  
  J Immunol.
  
  Volume: 200 Pages: 1839-1852
- DOI
  10.4049/jimmunol.1700544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08733, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17J06054, KAKENHI-PROJECT-17K19681, KAKENHI-PROJECT-17H01540
[Journal Article] Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models2018
- Author(s)
  Sasaki F., Koga T., Ohba M., Saeki K., Okuno T., Ishikawa K., Nakama T., Nakao S., Yoshida S., Ishibashi T., Ahmadieh H., Kanavi M. R., Hafezi-Moghadam A., Penninger J. M., Sonoda K. H., Yokomizo T.
- Journal Title
  
  JCI Insight
  
  Volume: 3 Pages: 96902-96902
- DOI
  10.1172/jci.insight.96902
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-18K06923, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-15K08316
[Journal Article] Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma2018
- Author(s)
  Makinoshima H et al.
- Journal Title
  
  Cancer Res
  
  Volume: - Pages: 2179-2190
- DOI
  10.1158/0008-5472.can-17-2109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07189, KAKENHI-PROJECT-16K14619, KAKENHI-PROJECT-17K07194, KAKENHI-ORGANIZER-15H05897
[Journal Article] イノシトールリン脂質におけるリン酸化クオリティ制御の病態生理学的意義2018
- Author(s)
  高須賀俊輔、佐々木雄彦
- Journal Title
  
  実験医学増刊（羊土社）
  
  Volume: 36 Pages: 1591-1607
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Journal Article] TMEM55a localizes to macrophage phagosomes to downregulate phagocytosis2018
- Author(s)
  Morioka Shin、Nigorikawa Kiyomi、Okada Eri、Tanaka Yoshimasa、Kasuu Yoshihiro、Yamada Miho、Kofuji Satoshi、Takasuga Shunsuke、Nakanishi Hiroki、Sasaki Takehiko、Hazeki Kaoru
- Journal Title
  
  Journal of Cell Science
  
  Volume: 131 Pages: 213272-213272
- DOI
  10.1242/jcs.213272
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-18K06623, KAKENHI-ORGANIZER-15H05897
[Journal Article] PIKfyve regulates melanosome biogenesis2018
- Author(s)
  Liggins Marc C.、Flesher Jessica L.、Jahid Sohail、Vasudeva Priya、Eby Victoria、Takasuga Shunsuke、Sasaki Junko、Sasaki Takehiko、Boissy Raymond E.、Ganesan Anand K.
- Journal Title
  
  PLOS Genetics
  
  Volume: 14
- DOI
  10.1371/journal.pgen.1007290
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06623, KAKENHI-ORGANIZER-15H05897, KAKENHI-PUBLICLY-18H04877, KAKENHI-PROJECT-17K19375
[Journal Article] The effect and possible clinical efficacy of in vivo inhibition of neutrophil extracellular traps by blockade of PI3K-gamma on the pathogenesis of microscopic polyangiitis2018
- Author(s)
  Kimura Hirotaka、Matsuyama Yasushi、Araki Sachiko、Koizumi Atsushi、Kariya Yumi、Takasuga Shunsuke、Eguchi Satoshi、Nakanishi Hiroki、Sasaki Junko、Sasaki Takehiko
- Journal Title
  
  Modern Rheumatology
  
  Volume: 28 Pages: 1-12
- DOI
  10.1080/14397595.2017.1367116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19375, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-18K06623
[Journal Article] Vacuolar protein sorting 34 regulates myofibril proteostasis to prevent hypertrophic cardiomyopathy2017
- Author(s)
  Kimura H, Eguchi S, Sasaki J, Kuba K, Nakanishi H, Takasuga S, Yamazaki M, Goto A, Watanabe H, Itoh H, Imai Y, Suzuki A, Mizushima N, Sasaki T
- Journal Title
  
  JCI insight
  
  Volume: 2(1) Pages: 89462-89478
- DOI
  10.1172/jci.insight.89462
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05978, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26253083, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-26460059, KAKENHI-PROJECT-26461458, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-15K15304, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-26440020, KAKENHI-PROJECT-26670132, KAKENHI-PROJECT-15K18857, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-26640081
[Journal Article] Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis.2017
- Author(s)
  Iizuka-Hishikawa Yoshiko、Hishikawa Daisuke、Sasaki Junko、Takubo Keiyo、Goto Motohito、Nagata Katsuyuki、Nakanishi Hiroki、Shindou Hideo、Okamura Tadashi、Ito Chizuru、Toshimori Kiyotaka、Sasaki Takehiko、Shimizu Takao
- Journal Title
  
  J Biol Chem
  
  Volume: 292 Pages: 12065-12076
- DOI
  10.1074/jbc.m117.791277
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19375, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-15K10638
[Journal Article] Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia2017
- Author(s)
  Matsumoto J, Nakanishi H, Kunii Y, Sugiura Y, Yuki D, Wada A, Hino M, Niwa SI, Kondo T, Waki M, Hayasaka T, Masaki N, Akatsu H, Hashizume Y, Yamamoto S, Sato S, Sasaki T, Setou M, Yabe H
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 7 Pages: 1-11
- DOI
  10.1038/srep45050
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-16H06145, KAKENHI-PROJECT-14J05334, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-26670132, KAKENHI-PROJECT-15K18857, KAKENHI-PROJECT-15K08608, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-26253006
[Journal Article] PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.2017
- Author(s)
  Malek M、Kielkowska A、Chessa T、Anderson K E.、Barneda D、Pir P、Nakanishi H、Eguchi S、Koizumi A、Sasaki J、Juvin V、Kiselev VY.、Niewczas I、Gray A、Valayer A、Spensberger D、Imbert M、Felisbino S、Habuchi T、Beinke S、Cosulich S、Le Novere N、Sasaki T、Clark J、Hawkins PT.、Stephens LR.
- Journal Title
  
  Mol Cell
  
  Volume: 68 Pages: 566-580
- DOI
  10.1016/j.molcel.2017.09.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19375, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-16H02679, KAKENHI-PROJECT-15H04693
[Journal Article] Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production2017
- Author(s)
  Huang Mingguo、Narita Shintaro、Inoue Takamitsu、Koizumi Atsushi、Saito Mitsuru、Tsuruta Hiroshi、Numakura Kazuyuki、Satoh Shigeru、Nanjo Hiroshi、Sasaki Takehiko、Habuchi Tomonori
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 111780-111794
- DOI
  10.18632/oncotarget.22908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-16H02679
[Journal Article] Biochemical and immunological characterization of a novel monoclonal antibody against mouseleukotriene B4 receptor 1.2017
- Author(s)
  Sasaki F, Koga T, Saeki K, Okuno T, Kazuno S, Fujimura T, Ohkawa Y, Yokomizo T
- Journal Title
  
  PLoS One.
  
  Volume: 12 Pages: 0185133-0185133
- DOI
  10.1371/journal.pone.0185133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-17K00874, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-15KK0320, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-17H03608
[Journal Article] Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells.2017
- Author(s)
  Shindou Hideo、Koso Hideto、Sasaki Junko、Nakanishi Hiroki、Sagara Hiroshi、Nakagawa Koh M.、Takahashi Yoshikazu、Hishikawa Daisuke、Iizuka-Hishikawa Yoshiko、Tokumasu Fuyuki、Noguchi Hiroshi、Watanabe Sumiko、Sasaki Takehiko、Shimizu Takao
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 292 Pages: 1205412064-1205412064
- DOI
  10.1074/jbc.m117.790568
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19375, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-15H04695, KAKENHI-PROJECT-16J01728
[Journal Article] Insufficient Lymph Drainage Causes Abnormal Lipid Accumulation and Vein Wall Degeneration2016
- Author(s)
  Tanaka H, Yamamoto N, Suzuki M, Mano Y, Sano M, Zaima N, Sasaki T, Setou M, Unno N.
- Journal Title
  
  Ann Vasc Dis
  
  Volume: 9 Issue: 4 Pages: 277-284
- DOI
  10.3400/avd.oa.16-00122
- NAID
  130005252750
- ISSN
  1881-641X, 1881-6428
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-26462104, KAKENHI-PROJECT-26293310
[Journal Article] Diet-induced alteration of fatty acid synthase in prostate cancer progression.2016
- Author(s)
  Huang M, Koizumi A, Narita S, Inoue T, Tsuchiya N, Nakanishi H, Numakura K, Tsuruta H, Saito M, Satoh S, Nanjo H, Sasaki T, Habuchi T
- Journal Title
  
  Oncogenesis.
  
  Volume: ５
- DOI
  10.1038/oncsis.2015.42
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670695, KAKENHI-PROJECT-25462466, KAKENHI-PROJECT-25293332
[Journal Article] Dysregulated YAP1/TAZ and TGFβ signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice2016
- Author(s)
  Nishio, M., Sugimachi, K., Goto, H., Wang, J., Morikawa, T., Miyachi, Y., Takano, Y., Hikasa, H., Itoh, T., Suzuki, S.O., Kurihara, H., Aishima, S., Leask, A., Sasaki, T., Nakano, T., Nishina, H., Nishikawa, Y., Sekido, Y., Nakao, K., Shin-ya, K., Mimori, K. and Suzuki, A.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 113 Pages: 71-80
- DOI
  10.1073/pnas.1517188113
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07052, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-15K15107, KAKENHI-PROJECT-15K19026, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-26670396, KAKENHI-PROJECT-24390092, KAKENHI-PROJECT-15H02536, KAKENHI-PROJECT-26293012
[Journal Article] Imaging mass spectrometry reveals a unique distribution of triglycerides in2016
- Author(s)
  Tanaka H, Zaima N, Sasaki T, Yamamoto N, Inuzuka K, Sano M, Saito T, Hayasaka T, Goto-Inoue N, Sato K, Kugo H, Moriyama T, Konno H, Setou M, Unno N.
- Journal Title
  
  J Vasc Res.
  
  Volume: 52 Pages: 127-135
- DOI
  10.1159/000439169
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462104, KAKENHI-PROJECT-26462105, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05900, KAKENHI-PROJECT-26293310, KAKENHI-PROJECT-25713024, KAKENHI-PROJECT-25293044, KAKENHI-PLANNED-15H05898
[Journal Article] Myeloid cell-specific inositol polyphosphate-4-phosphatase type I knockout mice impair bacteria clearance in a murine peritonitis modeｌ2016
- Author(s)
  Morioka S, Nigorikawa K, Sasaki J, Hazeki K, Kasuu Y, Sasaki T, Hazeki O
- Journal Title
  
  Innate Immun
  
  Volume: 6 Pages: 444-444
- DOI
  10.1177/1753425916652714
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-26253006
[Journal Article] イノシトールリン脂質のがん転移への関与 : "invadopodia"の形成機構2016
- Author(s)
  坂東倫行、佐々木雄彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 257 Pages: 1211-1215
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Journal Article] Characteristic Distribution Pattern of Lysophosphatidylcholine in Fibromuscular Dysplasia-Associated Visceral Artery Aneurysms Compared with Atherosclerotic Visceral Artery Aneurysms.2016
- Author(s)
  Tanaka H, Zaima N, Sasaki T, Yamamoto N, Inuzuka K, Sano M, Konno H, Urano T, Setou M, Unno N.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 印刷中
- NAID
  130005154756
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Journal Article] Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm.2016
- Author(s)
  Kugo H, Zaima N, Tanaka H, Mouri Y, Yanagimoto K, Hayamizu K, Hashimoto K, Sasaki T, Sano M, Yata T, Urano T, Setou M, Unno N, Moriyama T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Pages: 31268-31268
- DOI
  10.1038/srep31268
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-25713024, KAKENHI-PROJECT-26462104, KAKENHI-PROJECT-26293310
[Journal Article] Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins. F2016
- Author(s)
  Ishii Y, Saeki K, Liu M, Sasaki F, Koga T, Kitajima K, Meno C, Okuno T, Yokomizo T
- Journal Title
  
  Faseb J
  
  Volume: 30 Pages: 933-47
- DOI
  10.1096/fj.15-279653
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-26461637, KAKENHI-PROJECT-15K19032, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-25460374, KAKENHI-PROJECT-26291051, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-15KK0320
[Journal Article] イノシトールリン脂質のがん転移への関与 : "invadopodia"の形成機構2016
- Author(s)
  坂東倫行、佐々木雄彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 257 Pages: 1211-1215
- Data Source
  KAKENHI-PROJECT-15K14947
[Journal Article] イノシトールリン脂質のがん転移への関与 : "invadopodia"の形成機構2016
- Author(s)
  坂東倫行、佐々木雄彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 257 Pages: 1211-1215
- Data Source
  KAKENHI-PROJECT-26253006
[Journal Article] Development and evaluation of immunochromatography to detect Gram-negative bacteria producing ArmA 16S rRNA methylase responsible for aminoglycoside resistance.2016
- Author(s)
  Okochi Y, Aratani Y, Adissu HA, Miyawaki N, Sasaki M, Suzuki K, Okamura Y.
- Journal Title
  
  J Microbiol Methods
  
  Volume: 99 Pages: 159-163
- DOI
  10.1189/jlb.3hi0814-393r
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08175, KAKENHI-PROJECT-26450446, KAKENHI-PUBLICLY-26111712, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-24590277, KAKENHI-PROJECT-24659268, KAKENHI-PLANNED-15H05901
[Journal Article] Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment2015
- Author(s)
  Ip LR, Poulogiannis G, Viciano FC, Sasaki J, Kofuji S, Spanswick VJ, Hochhauser D, Hartley JA, Sasaki T, Gewinner CA
- Journal Title
  
  Oncotarget
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26253006
[Journal Article] INPP4B Is a PtdIns (3,4,5) P3 Phosphatase That Can Act as a Tumor Suppressor.2015
- Author(s)
  Kofuji, S., Kimura, H., Nakanishi, H., Nanjo, H., Takasuga, S., Liu, H., Eguchi, S., Nakamura, R., Itoh, R., Ueno, N., Asanuma, K., Huang, M., Koizumi, A., Habuchi, T., Yamazaki, M., Suzuki, A., Sasaki, J., Sasaki, T.
- Journal Title
  
  Cancer Discov.
  
  Volume: 5 Pages: 730-739
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Journal Article] INPP4B is a PtdIns(3,4,5)P3 phosphatase that can act as a tumor suppressor2015
- Author(s)
  Kofuji S, Kimura H, Nakanishi H, Nanjo H, Takasuga S, Liu H, Eguchi S, Nakamura R, Itoh R, Ueno N, Asanuma K, Huang M, Koizumi A, Habuchi T, Yamazaki M, Suzuki A, Sasaki J, Sasaki T
- Journal Title
  
  Cancer Discov.
  
  Volume: in press Pages: 730-739
- DOI
  10.1158/2159-8290.cd-14-1329
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-26440020, KAKENHI-PROJECT-26461458, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-26670695, KAKENHI-PROJECT-15K18857, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-26860686, KAKENHI-PROJECT-25293332
[Journal Article] INPP4BはPTEN欠損による発がんへのフェイルセーフ機構を担う2015
- Author(s)
  小藤智史，佐々木雄彦
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 450-453
- Data Source
  KAKENHI-PROJECT-15K14947
[Journal Article] In vivo role of INPP4B in tumor and metastasis suppression through regulation of PI3K/AKT signaling at endosomes.2015
- Author(s)
  Nigorikawa, K., Hazeki, K., Sasaki, J., Omori, Y., Miyake, M., Morioka, S., Guo, Y., Sasaki, T., Hazeki, O
- Journal Title
  
  Cancer Discov.
  
  Volume: 10 Pages: 740-751
- DOI
  10.1371/journal.pone.0142091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-26670132, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-15H04693
[Journal Article] INPP4BはPTEN欠損による発がんへのフェイルセーフ機構を担う2015
- Author(s)
  小藤智史，佐々木雄彦
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 450-453
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Journal Article] The ML1Nx2 Phosphatidylinositol 3,5Bisphosphate Probe Shows Poor Selectivity in Cells.2015
- Author(s)
  Hammond GR, Takasuga S, Sasaki T, Balla T.
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0139957
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460059, KAKENHI-PROJECT-15K14947, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-26253006
[Journal Article] Dachsous-dependent asymmetric localization of spiny-legs determines planar cell polarity orientation in Drosophila2015
- Author(s)
  Ayukawa T., Akiyama M., Mummery-Widmer JL., Stoeger T., Sasaki J., Knoblich JA., Senoo H., Sasaki T., Yamazaki M.
- Journal Title
  
  Cell Reports
  
  Volume: 8 Pages: 610-621
- DOI
  10.1016/j.celrep.2014.06.009
- NAID
  120005624821
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390067, KAKENHI-PUBLICLY-25117704, KAKENHI-PUBLICLY-25127703, KAKENHI-PROJECT-25711013, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-26440113, KAKENHI-PROJECT-26650074, KAKENHI-PROJECT-26670132
[Journal Article] In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes.2015
- Author(s)
  Chew CL, Lunardi A, Gulluni F, Ruan DT, Chen M, Salmena L, Nishino M, Papa A, Ng C, Fung J, Clohessy JG, Sasaki J, Sasaki T, Bronson RT, Hirsch E, Pandolfi PP
- Journal Title
  
  Cancer Discov.
  
  Volume: in press Pages: 740-751
- DOI
  10.1158/2159-8290.cd-14-1347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-15K14947, KAKENHI-PLANNED-15H05899
[Journal Article] INPP4BはPTEN欠損による発がんへのフェイルセーフ機構を担う2015
- Author(s)
  小藤智史，佐々木雄彦
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 450-453
- Data Source
  KAKENHI-PROJECT-26253006
[Journal Article] Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment.2015
- Author(s)
  Ip, LR., Poulogiannis, G., Viciano, FC., Sasaki, J., Kofuji, S., Spanswick, VJ., Hochhauser, D., Hartley, JA., Sasaki, T., Gewinner, CA.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 10548-10562
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14947
[Journal Article] ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration. C2015
- Author(s)
  Zandi S, Nakao S, Chun K H, Fiorina P, Sun D, Arita R, Zhao M, Kim E, Schueller O, Campbell S, Taher M, Melhorn M I, Schering A, Gatti F, Tezza S, Xie F, Vergani A, Yoshida S, Ishikawa K, Yamaguchi M, Sasaki F, Schmidt-Ullrich R, Hata Y, Enaida H, Yuzawa M, Yokomizo T, 4名
- Journal Title
  
  Cell Rep.
  
  Volume: 10 Pages: 1173-1186
- DOI
  10.1016/j.celrep.2015.01.050
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22116002, KAKENHI-PROJECT-24249083, KAKENHI-PROJECT-25713057, KAKENHI-PROJECT-15K10897, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708
[Journal Article] INPP4BはPTEN欠損による発がんへのフェイルセーフ機構を担う2015
- Author(s)
  小藤智史，佐々木雄彦
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 450-453
- Data Source
  KAKENHI-PLANNED-15H05899
[Journal Article] Hypoperfusion of the Adventitial Vasa Vasorum Develops an Abdominal Aortic Aneurysm.2015
- Author(s)
  Tanaka H, Zaima N, Sasaki T, Sano M, Yamamoto N, Saito T, Inuzuka K, Hayasaka T, Goto-Inoue N, Sugiura Y, Sato K, Kugo H, Moriyama T, Konno H, Setou M, Unno N.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- DOI
  10.1371/journal.pone.0134386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462104, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05900, KAKENHI-PLANNED-15H05898
[Journal Article] Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment.2015
- Author(s)
  Ip, LR., Poulogiannis, G., Viciano, FC., Sasaki, J., Kofuji, S., Spanswick, VJ., Hochhauser, D., Hartley, JA., Sasaki, T., Gewinner, CA.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 10548-10562
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05899
[Journal Article] Localizing the lipid products of PI3Kγ in neutrophils2015
- Author(s)
  Norton L, Lindsay Y, Deladeriere A, Chessa T, Guillou H, Suire S, Lucocq J, Walker S, Andrews S, Segonds-Pichon A, Rausch O, Finan P, Sasaki T, Du CJ, Bretschneider T, Ferguson GJ, Hawkins PT, Stephens L.
- Journal Title
  
  Adv Biol Regul
  
  Volume: 60 Pages: 36-45
- DOI
  10.1016/j.jbior.2015.10.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14947, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-26253006
[Journal Article] Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment.2015
- Author(s)
  Ip, LR., Poulogiannis, G., Viciano, FC., Sasaki, J., Kofuji, S., Spanswick, VJ., Hochhauser, D., Hartley, JA., Sasaki, T., Gewinner, CA.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 10548-10562
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Journal Article] Diet-induced macrophage inhibitory cytokine 1 promotes prostate cancer progression2014
- Author(s)
  Huang M, Narita S, Inoue T, Tsuchiya N, Satoh S, Nanjo H, Sasaki T, Habuchi T.
- Journal Title
  
  Endocr Relat Cancer
  
  Volume: 21 Pages: 39-50
- DOI
  10.1530/erc-13-0227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592374, KAKENHI-PROJECT-25293332
[Journal Article] The PtdIns(3, 4) P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death2010
- Author(s)
  Sasaki, J., Kofuji, S., Itoh, R., Momiyama, T., Takayama, K., Murakami, H., Chida, S., Tsuya, Y., Takasuga, S., Eguchi, S., Asanuma, K., Horie, Y., Miura, K., Davies, EM., Mitchell, C., Yamazaki, M., Hirai, H., Takenawa, T., Suzuki, A., and Sasaki, T
- Journal Title
  
  Nature
  
  Volume: 465 Pages: 497-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] The PtdIns(3,4)P_2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death.2010
- Author(s)
  Sasaki J., et al.
- Journal Title
  
  Nature
  
  Volume: 465 Pages: 497-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689003
[Journal Article] The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death2010
- Author(s)
  Sasaki J, Kofuji S, Itoh R, Momiyama T, Takayama K, Murakami H, Chida S, Tsuya Y, Takasuga S, Eguchi S, Asanuma K, Horie Y, Miura K, Davies EM, Mitchell C, Yamazaki M, Hirai H, Takenawa T, Suzuki A, Sasaki T
- Journal Title
  
  Nature
  
  Volume: 465 Pages: 497-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] The Ptdlns(3,4)P_2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death.2010
- Author(s)
  Sasaki J., et al.
- Journal Title
  
  Nature
  
  Volume: 465 Pages: 497-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659067
[Journal Article] Sequential Regulation of DOCK2 Dynamics by Two Phospholipids during Neutrophil Chemotaxis2009
- Author(s)
  Kunisaki, Y., Sasaki, T.(16名中14番), Fukui, Y.
- Journal Title
  
  Science
  
  Volume: 17 Pages: 384-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Involvement of proton-sensing TDAG8 in extracellular acidification-induced inhibition of proinflammatory cytokine production in peritoneal macrophages2009
- Author(s)
  Mogi, C., Sasaki, T.(14名中9番), Okajima, F.
- Journal Title
  
  J. Immunol
  
  Volume: 182 Pages: 3243-3251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Mammalian phosphoinositide kinases and phosphatases.2009
- Author(s)
  Sasaki T., et al.
- Journal Title
  
  Prog Lipid Res. 48
  
  Pages: 307-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659067
[Journal Article] Mammalian phosphoinositide kinases and phosphatases2009
- Author(s)
  Sasaki T., et al.
- Journal Title
  
  Prog Lipid Res. 48
  
  Pages: 307-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689003
[Journal Article] Allergic airway hyperresponsiveness,inflammation, and remodeling do not develop in phosphoinositide 3-kinase γ -deficient mice.2009
- Author(s)
  Takeda, M., Ito, W., Tanabe, M., Ueki, S., Kato, H., Kihara, J., Tanigai, T., Chiba, T., Yamaguchi, K., Kayaba, H., Imai, Y., Okuyama, K., Ohno, I., Sasaki, T. & Chihara, J.
- Journal Title
  
  123
  
  Pages: 805-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Mammalian phosphoinositide kinases and phosphatases2009
- Author(s)
  Sasaki T., et al.
- Journal Title
  
  Prog Lipid Res. 48
  
  Pages: 307-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013006
[Journal Article] Involvement of proton-sensing TDAG8 in extracellular acidification-induced inhibition of proinflammatory cytokine production in peritoneal macrophages.2009
- Author(s)
  Mogi C, Tobo M, Tomura H, Murata N, He XD, Sato K, Kimura T, Ishizuka T, Sasaki T., Sato T, Kihara Y, Ishii S, Harada A, & Okajima F.
- Journal Title
  
  J. Immunol 182
  
  Pages: 3243-3251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Sequential Regulation of DOCK2 Dynamics by Two Phospholipids during Neutrophil Chemotaxis.2009
- Author(s)
  Nishikimi, A., Fukuhara, H., Su, W., Hongu, T., Takasuga, S., Mihara, H., Cao, Q., Sanematsu, F., Kanai, M., Hasegawa, H., Tanaka, Y., Shibasaki, M., Kanaho, Y., Sasaki, T., Frohman, M.A., Fukui Y.
- Journal Title
  
  Science 324
  
  Pages: 384-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN dephosphorylates phosphatidylinositol 4,5-bisphosphate.2008
- Author(s)
  Iwasaki, H., Murata, Y., Kim, Y., Hossain, M., Worby, C., Dixon, J., McCormack, T., Sasaki, T. & Okamura, Y.
- Journal Title
  
  Proc. Natl. Acad.Sci 105
  
  Pages: 7970-7975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages2008
- Author(s)
  Kuroda, S., T., Sasaki, T.(14名中3番), Suzuki, A.
- Journal Title
  
  Eur J. Immunol
  
  Volume: 38 Pages: 1131-1140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] IGF-I secreted by osteoblasts acts as a poteint chemotactic factor for osteoblast.2008
- Author(s)
  Nakasaki, M, Yoshioka, K, Miyamoto, Y, Sasaki, T., Yoshikawa, H. & Itoh, K.
- Journal Title
  
  Bone 43
  
  Pages: 869-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.2008
- Author(s)
  Wang, Y., Litvinov, R., Xinsheng, D., Bach, T., Lian, L., Petrich, B., Monkley, S., Critcheley, D., Sasaki, T., Birnbaum, M., Weisel, J., Hartwig, J.& Abrams, C.
- Journal Title
  
  J. Clin. Invest 118
  
  Pages: 812-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages.2008
- Author(s)
  Kuroda, S., Nishio, M., Sasaki, T., Horie, Y., Kawahara, K., Sasaki, M., Natsui, M., Matozaki, T., Tezuka, H., Ohteki, T., Forster, I., Mak, T., Nakano, T.& Suzuki, A.
- Journal Title
  
  Eur J. Immunol 38
  
  Pages: 1131-1140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Critical roles of the p110β subtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264.7 cells.2008
- Author(s)
  Tsukamoto, K., Hazeki, K., Hoshi, M., Nigorikawa, K., Inoue. N., Sasaki, T. & Hazeki, O.
- Journal Title
  
  J. Immunol 180
  
  Pages: 2054-2061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis.2008
- Author(s)
  noue-Narita, T., Hamada, K., Sasaki, T., Hatakeyama, S., Fujita, S., Kawahara, K., Sasaki, M., Kishimoto, H., Eguchi, S., Kojima, I., Beermann, F., Kimura, T., Osawa, M., Itami, S., Mak, T., Nakano, T., Manabe, M. & Suzuki, A.
- Journal Title
  
  Cancer Res 68
  
  Pages: 5760-5768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] CD28 provides T cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.2008
- Author(s)
  Garcon, F., Patton, D., Emery, J., Hirsch, E., Rottapel, R., Sasaki, T. & Okkenhaug, K.
- Journal Title
  
  Blood 111
  
  Pages: 1464-1471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN dephosphorylates phosphatidylinositol 4, 5-bisphosphate2008
- Author(s)
  Iwasaki, H., Sasaki, T.(9名中8番), Okamura, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci
  
  Volume: 105 Pages: 7970-7975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Loss of PIP5KI ・ demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.2008
- Author(s)
  Wang, Y., Chen, X., Lian, L., Tang, T., Stalker, T., Sasaki, T., Brass, L., Choi, J., Hartwig, J. & Abrams, C.
- Journal Title
  
  Proc. Natl. Acad. Sci 105
  
  Pages: 14064-14069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] The PI3 kinase.-Akt pathway mediates renal tubular injury induced by cisplatin nephrotoxicity2008
- Author(s)
  Terada, Y., Sasaki, T.(8名中7番), Sasaki, S.
- Journal Title
  
  Kidney Int
  
  Volume: 180 Pages: 430-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] IGF-I secreted by osteoblasts acts as a poteint chemotactic factor for osteoblast2008
- Author(s)
  Nakasaki, M., Sasaki, T.(6名中4番), Itoh, K.
- Journal Title
  
  Bone
  
  Volume: 43 Pages: 869-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] The phosphoinositide-3 kinase-γ - Akt pathway mediates renal tubular injury in cisplatin nephrotoxicity.2008
- Author(s)
  Kuwana, H., Terada, Y., Kobayashi, T., Okado, T., Penninger, J., Sasaki, J., Sasaki, T. & Sasaki, S.
- Journal Title
  
  Kidney Int 73
  
  Pages: 430-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Critical roles of the p110βsubtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264. 7 cells2008
- Author(s)
  Tsukamoto, K., Sasaki, T.(7名中6番), Hazeki, O.
- Journal Title
  
  J. Immunol
  
  Volume: 180 Pages: 2054-2061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Loss of PIP5KI. demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation2008
- Author(s)
  Wang, Y., Sasaki, T.(10名中6番), Abrams, C.
- Journal Title
  
  Proc. Natl. Acad. Sci
  
  Volume: 105 Pages: 14064-14069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes2008
- Author(s)
  Wang, Y., Sasaki, T.(13名中9番), Abrams, C.
- Journal Title
  
  J. Clin. Invest
  
  Volume: 118 Pages: 812-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] CD28 provides T cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer2008
- Author(s)
  Garcon, F., Sasaki, T.(7名中6番), Okkenhaug, K.
- Journal Title
  
  Blood
  
  Volume: 111 Pages: 1464-1471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis2008
- Author(s)
  Inoue-Narita, T., Sasaki, T.(18名中3番), Suzuki, A.
- Journal Title
  
  Cancer Res
  
  Volume: 68 Pages: 5760-5768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Non-invasive visualization of the lipid product of class I PI3K in transgenic mouse models.2007
- Author(s)
  Sasaki, T., et. al.
- Journal Title
  
  Biochem. Soc. Trans. 35
  
  Pages: 245-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18050004
[Journal Article] Control of cell polarity and motility by the PI(3, 4, 5) P3 phosphatase SHIP12007
- Author(s)
  Nishio, M., Sasaki, T.(19名中19番)
- Journal Title
  
  SHIP1
  
  Volume: 9 Pages: 36-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Regulation of FcγR-stimulated phagocytosis by the 72 kDa inositol polyphosphate 5-phosphatase.2007
- Author(s)
  Horan K., Watanabe K., Kong A., Bailey C., Rasko J., Sasaki T. & Mitchell C.
- Journal Title
  
  Blood 110
  
  Pages: 4480-4491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] The physiology of phosphoinositides.2007
- Author(s)
  Sasaki, T., et. al.
- Journal Title
  
  Biol. Pharm. Bull. 9
  
  Pages: 1599-1604
- NAID
  110006380235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18050004
[Journal Article] The Pten/PI3K pathway governs the homeostasis of V ・14 iNKT cells.2007
- Author(s)
  Kishimoto H., Ohteki T., Yajima N., Kawahara K., Natsui M., Kawarasaki S., Hamada K., Horie Y., Kubo Y., Arase S., Taniguchi M., Vanhaesebroeck B., Mak T., Nakano T., Koyasu S., Sasaki T. & Suzuki A.
- Journal Title
  
  Blood 109
  
  Pages: 3316-3324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] PI(3)Kγ has an important context-dependent role in chemokinesis.2007
- Author(s)
  Ferguson J., Milne L., S. Kulkarni, Sasaki T., Walker S., Andrews S., Crabbe T., Finan P., Jones G., Jackson S., Camps M., Rommel C., Wymann M., Hirsch E., Hawkins P. & Stephens L.
- Journal Title
  
  Nature Cell Biol 9
  
  Pages: 86-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Regulation of FcγR-stimulated phagocytosis by the 72 kDa inositol polyphosphate 5-phosphatase2007
- Author(s)
  Horan, K., Sasaki, T.(7名中6番), Mitchell, C.
- Journal Title
  
  Blood
  
  Volume: 110 Pages: 4480-4491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0312
[Journal Article] Non-invasive visualization of the lipid product of class I PI3K in transgenic mouse models.2007
- Author(s)
  Sasaki, T., et. al.
- Journal Title
  
  Biochem. Soc.Trans. 35
  
  Pages: 245-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Control of cell polarity and motility by the PI(3,4,5)P3 phosphatase SHIP1.2007
- Author(s)
  Nishio, M., Watanabe, K., Sasaki, J., Taya, C., Takasuga, S., Iizuka, R., Balla T., Yamazaki M., Watanabe H., Itoh R., Kuroda S., Horie Y., Forster I., Mak T., Yonekawa H., Penninger J., Kanaho Y., Suzuki A. & Sasaki T.
- Journal Title
  
  Nature Cell Biol 9
  
  Pages: 36-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Interaction between telencepalin and ERM family proteins mediates dendritic filopodia formation.2007
- Author(s)
  Furutani Y., Matsuno H., Kawasaki M., Sasaki T., Mori K., Yoshihara Y.
- Journal Title
  
  J. Neurosci 27
  
  Pages: 8866-8876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas.2007
- Author(s)
  Yanagi, S., Kishimoto, H., Kawahara, K., Sasaki, T., Sasaki, M., Nishio, M., Yajima, N., Hamada, K., Horie, Y., Kubo, H., Mak, T., Nakano, T., Nakazato, M. & Suzuki, A.
- Journal Title
  
  J. Clin. Invest 117
  
  Pages: 2929-2940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Non-invasive visualization of the lipid product of class I PI3K in transgenic mouse models.2007
- Author(s)
  Sasaki, T., et. al.
- Journal Title
  
  Biochem. Soc. Trans. 35
  
  Pages: 245-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659073
[Journal Article] The physiology of phosphoinositides.2007
- Author(s)
  Sasaki, T., et. al.
- Journal Title
  
  Biol. Pharm. Bull. 9
  
  Pages: 1599-1604
- NAID
  110006380235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659073
[Journal Article] The physiology of phosphoinositides.2007
- Author(s)
  Sasaki, T., et. al.
- Journal Title
  
  Biol. Pharm. Bull. 9
  
  Pages: 1599-1604
- NAID
  110006380235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients.2006
- Author(s)
  Tsuruta, H., Kishimoto, H., Sasaki, T., Natsui, M., Shibata, Y., Tsuchiya, N., Horie, Y., Hamada, K., Yajima, N., Enomoto, K., Gordon, J., Mak, T., Nakano, T., Habuchi, T. & Suzuki, A.
- Journal Title
  
  Cancer Res 66
  
  Pages: 8389-8396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-・ and PTEN.2006
- Author(s)
  Zhao, M., Song, B., Pu, J., Wada, T., Reid, B., Tai, G., Wang, F., Guo, A., Walczysko, P., Gu, Y., Sasaki, T., Suzuki, A., Forrester, J., Bourne, H., Devreotes, P., McCaig, C. & Penninger, J.
- Journal Title
  
  Nature 442
  
  Pages: 457-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis.2006
- Author(s)
  Kunisaki, Y., Nishikimi, A., Tanaka, Y., Takii, R., Noda, M., Inayoshi, A., Watanabe, K., Sasazuki, T., Sasaki, T. & Fukui, Y.
- Journal Title
  
  J. Cell Biol 174
  
  Pages: 647-652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development.2006
- Author(s)
  Suzuki, T, Kanai, Y., Hara, T., Sasaki, J., Sasaki, T., Kohara, M., Maehama, T., Taya, C., Shitara, H., Yonekawa, H., Frohman, M., Yokozeki, T. & Kanaho, Y.
- Journal Title
  
  Mol. Cell. Biol 26
  
  Pages: 6149-6156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Hepatic gene expression in hepatocyte-specific Pten deficient mice showing steatohepatitis without ethanol challenge.2006
- Author(s)
  Sato W, Horie Y, Kataoka E, Ohshima S, Dohmen T, Iizuka M, Sasaki J, Sasaki T, Hamada K, Kishimoto H, Suzuki A, Watanabe S.
- Journal Title
  
  Hepatol. Res 34
  
  Pages: 256-265
- NAID
  10020405034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Src homology 2 (SH2)-containing 5'-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts.2006
- Author(s)
  Yogo, K., Mizutamari, M., Mishima, K., Takenouchi, H., Ishida-Kitagawa, N., Sasaki, T. & Takeya, T.
- Journal Title
  
  Endocrinology 147
  
  Pages: 3307-3317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689003
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.Sasaki
- Journal Title
  
  J.Exp.Med 201(In press)
- Data Source
  KAKENHI-PROJECT-16044204
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I alpha.2005
- Author(s)
  Sasaki J et al.
- Journal Title
  
  JOURNAL OF EXPERIMENTAL MEDICINE 201(6)
  
  Pages: 859-870
- Data Source
  KAKENHI-PROJECT-17659089
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.SASAKI
- Journal Title
  
  Journal of Experimental Medicine 201
  
  Pages: 859-870
- Data Source
  KAKENHI-PROJECT-16044204
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.Sasaki
- Journal Title
  
  J.Exp.Med 201(In press)
- Data Source
  KAKENHI-PROJECT-15687007
[Journal Article] ホスファチジルイノシトール4,5-二リン酸のコンパートメント化2005
- Author(s)
  佐々木雄彦ら
- Journal Title
  
  細胞工学 24(6)
  
  Pages: 607-611
- Data Source
  KAKENHI-PROJECT-17659089
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.Sasaki
- Journal Title
  
  J.Exp.Med 201(In press)
- Data Source
  KAKENHI-PROJECT-16017213
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.SASAKI
- Journal Title
  
  Journal of Experimental Medicine 201
  
  Pages: 859-870
- Data Source
  KAKENHI-PROJECT-16017213
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.SASAKI
- Journal Title
  
  Journal of Experimental Medicine 201
  
  Pages: 859-870
- Data Source
  KAKENHI-PROJECT-15687007
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.SASAKI
- Journal Title
  
  Journal of Experrmental Medicine 201
  
  Pages: 859-870
- Data Source
  KAKENHI-PROJECT-17025006
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.Sasaki
- Journal Title
  
  J.Exp.Med 201(In press)
- Data Source
  KAKENHI-PROJECT-16022207
[Journal Article] 細胞遊走ホスホイノシタイド動態の遺伝子学的解析2005
- Author(s)
  佐々木雄彦ら
- Journal Title
  
  脂質生化学研究 47
  
  Pages: 39-42
- Data Source
  KAKENHI-PROJECT-17659089
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α.2005
- Author(s)
  J.SASAKI
- Journal Title
  
  Journal of Experimental Medicine 201
  
  Pages: 859-870
- Data Source
  KAKENHI-PROJECT-17024005
[Patent] 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発2019
- Inventor(s)
  佐々木雄彦ほか6名
- Industrial Property Rights Holder
  佐々木雄彦ほか6名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-528909
- Filing Date
  2019
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Patent] 新規リン脂質およびその利用2017
- Inventor(s)
  佐々木雄彦、中西広樹、石川将己、上野紀子、江口賢史、佐々木純子
- Industrial Property Rights Holder
  秋田大学、Akita Lipid Technologies
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-051354
- Filing Date
  2017-03-14
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Patent] 新規リン脂質およびその利用2017
- Inventor(s)
  佐々木雄彦、中西広樹、石川将己、上野紀子、江口賢史、佐々木純子
- Industrial Property Rights Holder
  秋田大学、Akita Lipid Technologies
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-051354
- Filing Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-15K14947
[Patent] ホスホイノシタイド分離測定法の開発2017
- Inventor(s)
  中西広樹、佐々木雄彦、江口賢史、佐々木純子、中西貴代
- Industrial Property Rights Holder
  秋田大学、ALTe
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26440020
[Patent] 新規リン脂質およびその利用2017
- Inventor(s)
  中西広樹、佐々木雄彦、佐々木純子、江口賢史、中西貴代
- Industrial Property Rights Holder
  秋田大学、Akita Lipid Technologies
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-051354
- Filing Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-26253006
[Patent] ホスホイノシタイド分離測定法の開発2016
- Inventor(s)
  中西広樹、佐々木雄彦、佐々木純子、江口賢史、中西貴代
- Industrial Property Rights Holder
  秋田大学、Akita Lipid Technologies
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-144177
- Filing Date
  2016-07-20
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Patent] ホスホイノシタイド分離測定法の開発2016
- Inventor(s)
  佐々木雄彦、中西広樹、石川将己、上野紀子、江口賢史、佐々木純子
- Industrial Property Rights Holder
  秋田大学、Akita Lipid Technologies
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-144177
- Filing Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26253006
[Patent] 新規リン脂質およびその利用2016
- Inventor(s)
  江口賢史、佐々木雄彦、中西広樹、石川将己、上野紀子、佐々木純子
- Industrial Property Rights Holder
  秋田大学、ALTe
- Industrial Property Rights Type
  特許
- Filing Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26440020
[Patent] ホスホイノシタイド分離測定法の開発2016
- Inventor(s)
  中西広樹、佐々木雄彦、佐々木純子、江口賢史、中西貴代
- Industrial Property Rights Holder
  秋田大学、Akita Lipid Technologies
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-144177
- Filing Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] Functional analysis of voltage-sensing phosphatase in mouse sperm2019
- Author(s)
  Takafumi Kawai, Haruhiko Miyata, Hiroki Nakanishi, Souhei Sakata, Yoshifumi Okochi, Masahiko Watanabe, Kenji Sakimura,Takehiko Sasaki, Masahito Ikawa, Yasushi Okamura
- Organizer
  The 9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019) , 第96回日本生理学会年会合同大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] Molecular mechanisms of phosphoinositide signaling2019
- Author(s)
  Junko Sasaki,Satoshi Eguchi,Hiroki Nakanishi,Takehiko Sasaki
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] ホスホイノシタイドの異常と疾患2018
- Author(s)
  佐々木雄彦
- Organizer
  第176回東京脂質談話会
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] 電位依存性ホスファターゼVSP：14年を経て見えたこと、見えないこと2018
- Author(s)
  岡村康司、河合喬文、川鍋　陽、筒井秀和、坂田宗平、佐々木雄彦
- Organizer
  心血管膜輸送研究会2018「心臓・血管系の頑健性と精緻な制御を支える分子基盤の統合的解明」
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] The lipid phosphatase INPP4B is a tumor suppressor in the context of PTEN insufficiency2018
- Author(s)
  Takehiko Sasaki, Satoshi Kofuji, Shunsuke Takasuga, Junko Sasaki
- Organizer
  Workshop on Frontiers in Phosphatase Research and Drug Discovery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] リポクオリティがプレクストリン相同ドメインと生体膜の相互作用に与える影響2018
- Author(s)
  山本詠士、佐々木純子、Mark S.P. Sansom、佐々木雄彦
- Organizer
  第60回日本脂質生化学会
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] 細胞膜リン脂質動態の生理と病態：An overview2018
- Author(s)
  佐々木雄彦
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] 炎症性リン脂質シグナルを抑制する SHIP12017
- Author(s)
  佐々木雄彦
- Organizer
  第 36 回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] 生体脂質を見る、測る、理解する2017
- Author(s)
  佐々木雄彦
- Organizer
  第49回日本臨床検査医学会東北支部総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] 細胞膜リン脂質の動態と機能2017
- Author(s)
  佐々木雄彦
- Organizer
  東京工業大学科学技術創成研究院セミナー
- Place of Presentation
  東京工業大学（神奈川県・横浜市）
- Year and Date
  2017-03-31
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] ω3系脂肪酸代謝産物による肝庇護作用2016
- Author(s)
  森井真也子、上野紀子、中西広樹、蛇口琢、渡部亮、吉野裕顕、佐々木雄彦
- Organizer
  第15回生命科学研究会
- Place of Presentation
  東京都・港区
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] ホスホイノシタイドによる生体調節機構2016
- Author(s)
  佐々木雄彦
- Organizer
  第28回高遠・分子細胞生物学シンポジウム
- Place of Presentation
  長野県・伊那市
- Year and Date
  2016-08-26
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] A method for studying quality of phosphoinositides2016
- Author(s)
  Takehiko Sasaki, Hiroki Nakanishi, Satoshi Eguchi, Masaki Ishikawa, Akira Suzuki, Junko Sasaki
- Organizer
  第３９回日本分子生物学会年会（MBSJ2016）
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] ω3系脂肪酸代謝産物による肝庇護作用2016
- Author(s)
  森井真也子、上野紀子、中西広樹、蛇口琢、渡部亮、吉野裕顕、佐々木雄彦
- Organizer
  第15回生命科学研究会
- Place of Presentation
  ホテルメルパルク東京（東京都・港区）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] マウス精子における電位依存性ホスファターゼの機能2016
- Author(s)
  河合喬文、宮田治彦、中西広樹、坂田宗平、有馬大貴、宮脇奈那、大河内善史、渡辺雅彦、崎村建司、佐々木雄彦、伊川正人、岡村康司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌）
- Year and Date
  2016-03-24
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] リピドミクスによる疾患研究2016
- Author(s)
  佐々木雄彦
- Organizer
  神戸大学医学部セミナー
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2016-12-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] HMGB1及びLPSに誘導される炎症を抑制する新規低分子化合物の創製2016
- Author(s)
  中島槙吾, 玉田賢弥, 佐藤聡, 吉森篤史, 市木貴子, 佐々木文之, 横溝岳彦,田沼靖一
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] A method for studying quality of phosphoinositides2016
- Author(s)
  Takehiko Sasaki, Hiroki Nakanishi, Satoshi Eguchi, Masaki Ishikawa, Akira Suzuki, Junko Sasaki
- Organizer
  第３９回日本分子生物学会年会（MBSJ2016）
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] A method for studying quality of phosphoinositides2016
- Author(s)
  Takehiko Sasaki
- Organizer
  第３９回日本分子生物学会年会（MBSJ2016）
- Place of Presentation
  神奈川県・横浜市
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] リピドミクスによる疾患研究2016
- Author(s)
  佐々木雄彦
- Organizer
  神戸大学医学部セミナー
- Place of Presentation
  神戸大学（兵庫県・神戸市）
- Year and Date
  2016-12-22
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] イノシトールリン脂質代謝と病態2016
- Author(s)
  佐々木雄彦
- Organizer
  脂質栄養学会第２５回大会
- Place of Presentation
  秋田市にぎわい交流館AU（秋田県・秋田市）
- Year and Date
  2016-09-17
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] Generation of chimeric high-affinity monoclonal antibody for FLAG tag2016
- Author(s)
  Ikeda, K., Sasaki, F., Ueno, A., Okuno, T., Koga, T.,Yokomizo, T.
- Organizer
  ASBMB meeting
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] A method for studying quality of phosphoinositides2016
- Author(s)
  Takehiko Sasaki, Hiroki Nakanishi, Satoshi Eguchi, Masaki Ishikawa, Akira Suzuki, Junko Sasaki
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26440020
[Presentation] リピドミクスによる疾患研究2016
- Author(s)
  佐々木雄彦
- Organizer
  九州大学大学院歯学府セミナー
- Place of Presentation
  福岡県・福岡市
- Year and Date
  2016-12-21
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] イノシトールリン脂質代謝と病態2016
- Author(s)
  佐々木雄彦
- Organizer
  脂質栄養学会第２５回大会
- Place of Presentation
  秋田県秋田市
- Year and Date
  2016-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] HMGB1/RAGE相互作用を阻害する新規低分子化合物の創製2016
- Author(s)
  玉田賢弥, 中島槙吾, 佐藤聡, 吉森篤史, 市木貴子, 佐々木文之, 横溝岳彦, 鈴木雄祐, 渡邊伸央, 井上茂亮,田沼靖一
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] イノシトールリン脂質代謝と病態2016
- Author(s)
  佐々木雄彦
- Organizer
  脂質栄養学会第２５回大会
- Place of Presentation
  秋田県・秋田市
- Year and Date
  2016-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] ホスホイノシタイドによる生体調節機構2016
- Author(s)
  佐々木雄彦
- Organizer
  第28回高遠・分子細胞生物学シンポジウム
- Place of Presentation
  長野県伊那市
- Year and Date
  2016-08-26
- Invited
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] ホスホイノシタイドによる生体調節機構2016
- Author(s)
  佐々木雄彦
- Organizer
  第28回高遠・分子細胞生物学シンポジウム
- Place of Presentation
  高遠さくらホテル（長野県・伊那市）
- Year and Date
  2016-08-26
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] ω3系脂肪酸代謝産物による肝庇護作用2016
- Author(s)
  森井真也子、上野紀子、中西広樹、蛇口琢、渡部亮、吉野裕顕、佐々木雄彦
- Organizer
  第15回生命科学研究会
- Place of Presentation
  東京都港区
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] イノシトールリン脂質代謝と疾患2016
- Author(s)
  佐々木雄彦
- Organizer
  九州大学大学院歯学府セミナー
- Place of Presentation
  九州大学（福岡県・福岡市）
- Year and Date
  2016-12-21
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] イノシトールリン脂質研究の新しい方法論の提示2015
- Author(s)
  中西広樹、小藤智史、江口賢史、中村亮太郎、石川将己、高須賀俊輔、佐々木純子、佐々木雄彦
- Organizer
  第14回生命科学研究会
- Place of Presentation
  神奈川
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] Measuring Phosphoinositides at Molecular Species Level2015
- Author(s)
  Hiroki Nakanishi1,3, Satoshi Eguchi2, Masaki Ishikawa1, Akira Suzuki4, Junko Sasaki2, Takehiko Sasaki
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫・神戸）
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] Measuring Phosphoinositides at Molecular Species Level2015
- Author(s)
  Hiroki Nakanishi, Satoshi Eguchi, Masaki Ishikawa, Akira Suzuki, Junko Sasaki, Takehiko Sasaki
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PLANNED-15H05899
[Presentation] 心肥大におけるホスホイノシタイド代謝酵素Vps34のタンパク質分解機構の役割2015
- Author(s)
  木村洋貴、江口賢史、久場敬司、今井由美子、高須賀俊輔、伊藤玲悦、中村亮太郎、中西広樹、石川将己、佐々木純子、山崎正和、佐々木雄彦
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] A New Methodology for Studying Phosphoinositide Signaling at the Molecular Species Level.2015
- Author(s)
  Takehiko Sasaki
- Organizer
  Keystone Symposium “PI 3-Kinase Signaling Pathways in Disease”
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] 心肥大におけるホスホイノシタイド代謝酵素Vps34のタンパク質分解機構の役割2015
- Author(s)
  木村洋貴、江口賢史、久場敬司、今井由美子、高須賀俊輔、伊藤玲悦、中村亮太郎、中西広樹、石川将己、佐々木純子、山崎正和、佐々木雄彦
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] 心肥大におけるホスホイノシタイド代謝酵素Vps34のタンパク質分解機構の役割2015
- Author(s)
  木村洋貴、江口賢史、久場敬司、今井由美子、高須賀俊輔、伊藤玲悦、中村亮太郎、中西広樹、石川将己、佐々木純子、山崎正和、佐々木雄彦
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PLANNED-15H05899
[Presentation] イノシトールリン脂質研究の新しい方法論の提示2015
- Author(s)
  中西広樹、小藤智史、江口賢史、中村亮太郎、石川将己、高須賀俊輔、佐々木純子、佐々木雄彦
- Organizer
  第14回生命科学研究会
- Place of Presentation
  神奈川
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] 心肥大におけるホスホイノシタイド代謝酵素Vps34のタンパク質分解機構の役割2015
- Author(s)
  木村洋貴、江口賢史、久場敬司、今井由美、高須賀俊輔、伊藤玲悦、中村亮太郎、中西広樹、石川将己、佐々木純子、山崎正和、佐々木雄彦
- Organizer
  第３８回日本分子生物学会年会、第８８回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26440020
[Presentation] ホスホイノシタイドの新しい解析方法2015
- Author(s)
  中西広樹、江口賢史、石川将己、鈴木聡、佐々木純子、佐々木雄彦
- Organizer
  第３８回日本分子生物学会年会、第８８回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26440020
[Presentation] Measuring Phosphoinositides at Molecular Species Level2015
- Author(s)
  Hiroki Nakanishi, Satoshi Eguchi, Masaki Ishikawa, Akira Suzuki, Junko Sasaki, Takehiko Sasaki
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-15K14947
[Presentation] ロイコトリエンB4第一受容体(BLT1)とFLAGタグに対するマウス単クローン抗体のヒトキメラ化2015
- Author(s)
  池田恒基, 佐々木文之, 上野あゆみ, 佐伯和子, 奥野利明, 古賀友紹, 横溝岳彦
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県・神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] 心肥大におけるホスホイノシタイド代謝酵素Vps34のタンパク質分解機構の役割2015
- Author(s)
  木村洋貴、江口賢史、久場敬司、今井由美子、高須賀俊輔、伊藤玲悦、中村亮太郎、中西広樹、石川将己、佐々木純子、山崎正和、佐々木雄彦
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫・神戸）
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-ORGANIZER-15H05897
[Presentation] Measuring Phosphoinositides at Molecular Species Level2015
- Author(s)
  Hiroki Nakanishi, Satoshi Eguchi, Masaki Ishikawa, Akira Suzuki, Junko Sasaki, Takehiko Sasaki
- Organizer
  第38回日本分子生物学会年会・第88回生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] T細胞におけるホスホイノシタイド代謝酵素PIK3C3の生理的役割2014
- Author(s)
  江口賢史、木村洋貴、佐々木純子、佐々木雄彦
- Organizer
  第８７回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26440020
[Presentation] Critical roles of class III PI3K in myofibril maintenance and protein quality control in cardiomyocytes2014
- Author(s)
  Takehiko Sasaki
- Organizer
  Symposium on Hormones and Cell Regulation European Society of Endocrinology
- Place of Presentation
  Mont Ste Odile, France
- Year and Date
  2014-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-26253006
[Presentation] Diet induced alteration of fatty acid synthase is involved in prostate cancer progression2014
- Author(s)
  Mingguo Huang, Shintaro Narita, Norihiko Tsuchiya, Takamitsu Inoue, Shigeru Satoh, Hiroshi Nanjo, Takehiko Sasaki, Tomonori Habuchi
- Organizer
  American Urological Association Annual Meeting 2014
- Place of Presentation
  Orland, Florida, USA
- Data Source
  KAKENHI-PROJECT-25293332
[Presentation] Role for 3-Phosphoinositide Metabolism in vivo.2011
- Author(s)
  Sasaki, T.
- Organizer
  Keystone Symposium "PI 3-Kinase Signaling Pathways"
- Place of Presentation
  Keystone, CO, USA
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-21659067
[Presentation] Role for 3-Phosphoinositide Metabolism in vivo.2011
- Author(s)
  Sasaki, T.
- Organizer
  Keystone Symposium"PI 3-Kinase Signaling Pathways"
- Place of Presentation
  Keystone, CO, USA
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-21689003
[Presentation] In vivo Role of Inositol Polyphosphate Phosphatase 4A2009
- Author(s)
  Sasaki, T.
- Organizer
  Keystone Symposium
- Place of Presentation
  Olympic Valley, CA, USA
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-20013006
[Presentation] In vivo Role of Inositol Polyphosphate Phosphatase 4A.2009
- Author(s)
  Sasaki, T.
- Organizer
  Keystone Symposium
- Place of Presentation
  Olympic Valley, CA, USA
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-21689003
[Presentation] In vivo Role of Inositol Polyphosphate Phosphatase 4A Keystone2009
- Author(s)
  佐々木雄彦
- Organizer
  Symposium "PI3-Kinase Signaling in Disease"
- Place of Presentation
  Olympic Valley, CA, USA
- Year and Date
  2009-04-25
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] In vivo Role of Inositol Polyphosphate Phosphatase 4A.2009
- Author(s)
  Sasaki, T.
- Organizer
  Keystone Symposium
- Place of Presentation
  Olympic Valley, CA, USA
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-21659067
[Presentation] Regulation of neutrophil chemotaxis by cellular lipids2008
- Author(s)
  佐々木雄彦
- Organizer
  42nd Annual Scientific Meeting of the European Society for Clinical Investigation"Phagocyte biology:Molecular basis of innate immunity and chronic inflammation"
- Place of Presentation
  Geneva、 Switzerland
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] Control of chemotaxis by cellular lipids2008
- Author(s)
  Sasaki, T.
- Organizer
  42nd meeting of the European Society for Clinical Investigation
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18050004
[Presentation] Control of chemotaxis by cellular lipids2008
- Author(s)
  Sasaki, T.
- Organizer
  42nd meeting of the European Society for Clinical Investigation
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] Control of chemotaxis by cellular lipids2008
- Author(s)
  Sasaki, T.
- Organizer
  42nd meeting of the European Society for Clinical Investigation
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18659073
[Presentation] 神経細胞におけるL-PIPaseの機能2008
- Author(s)
  佐々木雄彦
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] 神経細胞におけるL-PIPase の機能2008
- Author(s)
  佐々木雄彦
- Organizer
  第31 回日本分子生物学会大会第 81 回日本生化学会大会合同大会 BMB2008 シンポジウム「リン脂質シグナリングと生体膜のダイナミクス」
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] 神経細胞におけるL-PIPaseの機能2008
- Author(s)
  佐々木雄彦
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20013006
[Presentation] Roles of 3-phosphorylated phosphoinositides2007
- Author(s)
  佐々木雄彦
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会、ミニシンポジウム
- Place of Presentation
  福岡
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] 神経細胞におけるL-PIPaseの機能2007
- Author(s)
  佐々木雄彦
- Organizer
  第30 回日本分子生物学会大会第80 回日本生化学会大会合同大会「細胞制御のオーガナイザーとしてのホスファターゼスーパーファミリー」ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] Role of Phosphoinositide Phosphatase in Neutrophil Migration2006
- Author(s)
  佐々木雄彦
- Organizer
  Biochemical Society Focused Meeting、"3rd Focused Meeting on PI3K signalling and disease"、シンポジウム
- Place of Presentation
  Bath, UK
- Year and Date
  2006-11-07
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] ホスホイノシタイドキナーゼ/ホスファターゼのマウス個体における機能2006
- Author(s)
  佐々木雄彦
- Organizer
  第48回日本脂質生化学会総会、シンポジウム
- Place of Presentation
  東京
- Year and Date
  2006-06-08
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] Role of Phosphoinositide Phosphatase in Neutrophil Chemotaxis2006
- Author(s)
  佐々木雄彦
- Organizer
  The 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress "New aspects of phosphoinositide signaling"、シンポジウム
- Place of Presentation
  京都
- Year and Date
  2006-06-21
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] イノシトールリン脂質代謝異常による細胞空胞化2006
- Author(s)
  佐々木雄彦
- Organizer
  日本分子生物学会2006フォーラム、メンブレントラフィックの奔流-分子から機能へ-、シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2006-12-06
- Data Source
  KAKENHI-PROJECT-18689003
[Presentation] Diet induced alteration of fatty acid synthase is involved in prostate cancer progression
- Author(s)
  Mingguo Huang, Shintaro Narita, Norihiko Tsuchiya, Takamitsu Inoue, Shigeru Satoh, Hiroshi Nanjo, Takehiko Sasaki, Tomonori Habuchi
- Organizer
  American Urological Association Annual Meeting 2014
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25293332

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# of Collaborated Products: 8 results
2. SASAKI Junko (30333371)

# of Collaborated Projects: 7 results

# of Collaborated Products: 27 results
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SASAKI TAKEHIKO 佐々木 雄彦

SASAKI Takehiko 佐々木 雄彦

Research Projects

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Co-Researchers

ホスホイノシタイド分子種の多様性と機能の解明Principal InvestigatorOngoing

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ホスホイノシチド動態制御を介したヒトパピローマウイルス潜伏感染機構の解明Ongoing

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分泌型膜リン脂質の生物活性の発見Principal InvestigatorOngoing

Principal Investigator

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脂質からみたオートファジーの膜動態Ongoing

Principal Investigator

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新規生体脂質の代謝機構と機能の解明Principal InvestigatorOngoing

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膜リン脂質クオリティ分析技術の開発と生命現象への適用Principal InvestigatorOngoing

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Development of a mouse model of microscopic polyangiitisPrincipal Investigator

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「リポクオリティ」領域研究の推進Ongoing

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Metabolism and functions of novel phospholipidsPrincipal Investigator

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脂肪性肝炎と炎症性腸疾患の進展に寄与する脂質メディエーターの同定Principal Investigator

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SASAKI TAKEHIKO 佐々木雄彦

SASAKI Takehiko 佐々木雄彦