NIIZUMA KUNIYASU 新妻邦泰

… Alternative Names

Researcher Number	10643330
Other IDs
Affiliation (Current)	2020: 東北大学, 医工学研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 東北大学, 医工学研究科, 教授 2017: 東北大学, 大学病院, 講師 2016: 東北大学, 医学(系)研究科(研究院), 助教 2016: 東北大学, 医学系研究科, 助教 2014 – 2016: 東北大学, その他の研究科, 助教 2014 – 2015: 東北大学, 医工学研究科, 助教 2013: 東北大学, 医学(系)研究科(研究院), 非常勤講師
Review Section/Research Field	Principal Investigator Neurosurgery / Science and Engineering / Medical systems / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Medical systems / Basic Section 62010:Life, health and medical informatics-related
Keywords	Principal Investigator 脳動脈瘤 / 数値流体力学 / くも膜下出血 / 数値流体解析 / 脳血管障害学 / 脳神経外科学 / 動脈硬化 / 多元計算解剖 / シミュレーション / 数値流体力学解析 … More Except Principal Investigator もやもや病 / 数値流体力学 / 脳動脈瘤 / 血管新生 / 幹細胞移植 / 再生医療 / 脊髄損傷 / Muse細胞 / 機械学習 / 脳動静脈奇形 / 集学的治療 / MRI / 脳血管撮影 / 数値流体解析 / 脳神経外科学 / 脳血管障害学 / moyamoya disease / RNF213 / MUSE細胞 / 再生療法 / 脳・神経 / 頭部外傷 / 外科 / 脳低温療法 / 神経外傷 / CED法 / コンピュータ・シミュレーション / 血行動態 / 頸動脈 / プラーク / CFD / WSS / OSI / drug delivery / cell therapy / ドラッグデリバリー / 神経再生 / ドラッグ・デリバリー・デリバリー / 脳動脈解離 / 穿通枝 / 脳血管内治療 / ステント / 流体力学 / 多能性幹細胞 / 組織修復 / 細胞移植治療 / 中枢神経疾患 / エラスチン / バイオマーカー / ラット / 慢性脳虚血 / 再灌流 / 過灌流 / 動脈内皮障害 / エストロゲン / 慢性脳虚血後過灌流モデル / 血管内皮障害 / Optogenetics / Cell therapy / epilepsy / seizure model / hippocampus / status epilepticus / regenerative medicine / optogenetics / 細胞治療 / 難治てんかん / 海馬光けいれんモデル / コンピュータ / くも膜下出血 / 急性期脳損傷 / エダラボン / ドラッグ・リポジショニング / S1P / subarachnoid hemorrhage / blood brain barrier / sphingosine-1-phosphate / S1PR1 / 頭蓋外内バイパス術 / RNF213 p.R4810K / 血管リモデリング / 人工知能 Less

Development of Muse cell therapy for dementiaPrincipal InvestigatorOngoing
- Principal Investigator
  
  新妻邦泰
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Tohoku University
くも膜下出血後早期脳損傷の軽減をめざして：エダラボンのドラッグリポジショニングOngoing
- Principal Investigator
  
  針生新也
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
S1PR1シグナル制御による脳血液関門保護を介したくも膜下出血の新規治療法開発Ongoing
- Principal Investigator
  
  伊藤明
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
シロスタゾールを用いたもやもや病における内因性幹細胞賦活と血管新生促進療法の開発Ongoing
- Principal Investigator
  
  藤村幹
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
Analysis of latent imaging findings in healthy subjects with moyamoya disease susceptibility gene RNF213 polymorphism using artificial intelligenceOngoing
- Principal Investigator
  
  園部真也
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Tohoku University
Muse細胞を用いた脊髄損傷に対する新しい細胞移植治療法の開発Ongoing
- Principal Investigator
  
  遠藤俊毅
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
エラスチン架橋アミノ酸に着目したもやもや病バイオマーカー診断法の確立Ongoing
- Principal Investigator
  
  井上智夫
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
新規慢性脳虚血および脳血管内皮機能障害モデルの開発と血流再建後過灌流機序の解明Ongoing
- Principal Investigator
  
  清水宏明
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Akita University
Muse細胞を用いたてんかん原性治癒手法の確立Ongoing
- Principal Investigator
  
  大沢伸一郎
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
未破裂脳動脈瘤の増大に決定的な役割を果たす血行力学的因子の解明Ongoing
- Principal Investigator
  
  杉山慎一郎
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
重症型もやもや病に対する多能性幹細胞Museを用いた血管新生療法の開発Ongoing
- Principal Investigator
  
  藤村幹
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
Platform for regenerative therapy of central nervous system using Muse cellsOngoing
- Principal Investigator
  
  冨永悌二
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
Development of risk evaluation system of cerebral aneurysms based on the computational fluid dynamicsPrincipal InvestigatorOngoing
- Principal Investigator
  
  新妻邦泰
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Medical systems
- Research Institution
  Tohoku University
Computational fluid dynamics in plaque formation of carotid artery
- Principal Investigator
  
  Saito Atsushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
New concept of local chemo- and cell-therapy for spinal cord injury using convection-enhanced drug delivery
- Principal Investigator
  
  Sugiyama Shinichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
正常から病態へ　～脳動脈瘤の発生に関する多元計算解剖学的アプローチ～Principal Investigator
- Principal Investigator
  
  新妻邦泰
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Multidisciplinary Approach for Arteriovenous Malformation Based on Computational Fluid Dynamics
- Principal Investigator
  
  Shimizu Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Akita University
Establishment of the stem cell transplantation therapy by MUSE for moyamoya disease
- Principal Investigator
  
  Miki Fujimura
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
Brain protection by local hypothermia in the acute phase of traumatic brain injury
- Principal Investigator
  
  Tominaga Teiji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
Development of stent to treat vertebral artery dissection: achievement of curability and functional preservation
- Principal Investigator
  
  ENDO Hidenori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
Prediction of the wall property and rupture risk of cerebral aneurysms based on the computational fluid dynamicsPrincipal Investigator
- Principal Investigator
  
  Niizuma Kuniyasu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University

All 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] 脳梗塞におけるMuse細胞を用いた治用戦略2019
- Author(s)
  新妻邦泰、冨永悌二
- Journal Title
  
  血液フロンティア
  
  Volume: 29 Pages: 47-57
- Data Source
  KAKENHI-PROJECT-17H01583
[Journal Article] Stress-induced tRNA cleavage and tiRNA generation in rat neuronal PC12 cells2018
- Author(s)
  Alaa E、Mishima E、Niizuma K、Akiyama Y、Fujimura M、Tominaga T、Abe T
- Journal Title
  
  J Neurochem
  
  Volume: -
- DOI
  10.1111/jnc.14321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01583, KAKENHI-PROJECT-16K19474
[Journal Article] Increased serum production of soluble CD163 and CXCL5 in patients with moyamoya disease: Involvement of intrinsic immune reaction in its pathogenesis.2018
- Author(s)
  Fujimura M, Fujimura T, Kakizaki A, Sato-Maeda M, Niizuma K, Tomata Y, Aiba S, Tominaga T
- Journal Title
  
  Brain Res
  
  Volume: 1679 Pages: 39-44
- DOI
  10.1016/j.brainres.2017.11.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10815, KAKENHI-PROJECT-16K10143
[Journal Article] Paradoxical Association of Symptomatic Local Vasogenic Edema with Global Cerebral Hypoperfusion after Direct Revascularization Surgery for Adult Moyamoya Disease.2018
- Author(s)
  Tashiro R, Fujimura M, Mugikura S, Niizuma K, Endo H, Endo T, Tominaga T
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: -
- DOI
  10.1016/j.jstrokecerebrovasdis.2018.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10815, KAKENHI-PROJECT-17H04255, KAKENHI-PROJECT-26461877
[Journal Article] A Novel Chronic Cerebral Hypoperfusion Model with Cognitive Impairment and Low Mortality Rate in Rats2018
- Author(s)
  Mansour A、Niizuma K、Rashad S、Sumiyoshi A、Endo H、Endo T、Sato K、Kawashima R、Tominaga
- Journal Title
  
  J Neurosurg
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01583
[Journal Article] Impact of bifurcation angle and inflow coefficient on the rupture risk of bifurcation type basilar artery tip aneurysms.2018
- Author(s)
  Sherif Rashad, Shin-ichiro Sugiyama, Kuniyasu Niizuma, Kenichi Sato, Hidenori Endo, Shunsuke Omodaka, Yasushi Matsumoto, Miki Fujimura, Teiji Tominaga
- Journal Title
  
  J Neurosurg
  
  Volume: in press Pages: 723-730
- DOI
  10.3171/2016.10.jns161695
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01102, KAKENHI-PROJECT-17H01583
[Journal Article] Biphasic development of focal cerebral hyperperfusion after revascularization surgery for adult moyamoya disease associated with autosomal dominant polycystic kidney disease2018
- Author(s)
  Tashiro R, FUJIMURA M, Endo H, Endo T, Niizuma K, Tominaga T
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 27 Pages: 3256-3260
- DOI
  10.1016/j.jstrokecerebrovasdis.2018.07.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10815
[Journal Article] Application of Muse Cell Therapy to Stroke2018
- Author(s)
  Niizuma K, Borlongan C V, Tominaga T.
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 1103 Pages: 167-186
- DOI
  10.1007/978-4-431-56847-6_9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01583
[Journal Article] Navigation-guided clipping of a de novo aneurysm associated with superficial temporal artery-middle cerebral artery bypass combined with indirect pial synangiosis in a patient with moyamoya disease2017
- Author(s)
  Aburakawa D, Fujimura M, Niizuma K, Sakata H, Endo H, Tominaga T
- Journal Title
  
  Neurosurg Rev
  
  Volume: 40 Pages: 517-521
- DOI
  10.1007/s10143-017-0866-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10815
[Journal Article] Embolization of ruptured arteriovenous malformations in the cerebellopontine angle cistern.2017
- Author(s)
  Endo H, Osawa SI, Matsumoto Y, Endo T, Sato K, Niizuma K, Fujimura M, Tominaga T.
- Journal Title
  
  Neurosurg Rev.
  
  Volume: 印刷中
- DOI
  10.1007/s10143-017-0832-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861138
[Journal Article] Prediction of the Initiation of Cerebral Aneurysms2017
- Author(s)
  Kuniyasu Niizuma, Takanobu Yagi, Shin-ichiro Sugiyama, Atsuhiro Nakagawa, Teiji Tominaga
- Journal Title
  
  The 3nd International Symposium on Multidisciplinary Computational Anatomy
  
  Volume: 3
- Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01102
[Journal Article] Transient global cerebral ischemia induces RNF213, a moyamoya disease susceptibility gene, in vulnerable neurons of the rat hippocampus CA1 sub-region and ischemic cortex2017
- Author(s)
  Sato-Maeda M, Fujimura M, Rashad S, Morita-Fujimura Y, Niizuma K, Sakata H, Ikawa S, Tominaga T.
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 26 Pages: 1904-1911
- DOI
  10.1016/j.jstrokecerebrovasdis.2017.06.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07152, KAKENHI-PROJECT-17K10815
[Journal Article] Uneven cerebral hemodynamic change as a cause of neurological deterioration in the acute stage after direct revascularization for moyamoya disease: cerebral hyperperfusion and remote ischemia caused by the 'watershed shift'.2017
- Author(s)
  Tu XK, Fujimura M, Rashad S, Mugikura S, Sakata H, Niizuma K, Tominaga T
- Journal Title
  
  Neurosurg Rev.
  
  Volume: - Pages: 507-512
- DOI
  10.1007/s10143-017-0845-9
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462150, KAKENHI-PROJECT-26461877, KAKENHI-PROJECT-17K10815, KAKENHI-PROJECT-17H04255
[Journal Article] De novo development of moyamoya disease in an adult female with a genetic variant of the RNF-213 gene: case report2017
- Author(s)
  Tashiro R, Fujimura M, Niizuma K, Endo H, Sakata H, Sato-Maeda M, Tominaga T
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 26
- DOI
  10.1016/j.jstrokecerebrovasdis.2016.09.035
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462150
[Journal Article] Temporal profile of magnetic resonance angiography and decreased ratio of regulatory T cells after immunological adjuvant administration to mice lacking RNF213, a susceptibility gene for moyamoya disease2016
- Author(s)
  Kanoke A, Fujimura M, Niizuma K, Fujimura T, Kakizaki A, Ito A, Sakata H, Sato-Maeda M, Kure S, Tominaga T.
- Journal Title
  
  Brain Res
  
  Volume: 1642 Pages: 1-9
- DOI
  10.1016/j.brainres.2016.03.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04871, KAKENHI-PROJECT-26462150, KAKENHI-PROJECT-15K15385
[Journal Article] Long-term follow-up of pediatric Moyamoya disease treated by combined direct-indirect revascularization surgery: Single institute experience with surgical and perioperative management2016
- Author(s)
  Rashad S, Fujimura M, Niizuma K, Endo H, Tominaga T
- Journal Title
  
  Neurosurg Rev
  
  Volume: 39 Pages: 615-623
- DOI
  10.1007/s10143-016-0734-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462150
[Journal Article] Prediction of the initiation of cerebral aneurysms2016
- Author(s)
  Kuniyasu Niizuma, Takanobu Yagi, Shin-ichiro Sugiyama, Atsuhiro Nakagawa, and Teiji Tominaga
- Journal Title
  
  The 2nd International Symposium on Multidisciplinary Computational Anatomy
  
  Volume: -
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25713051
[Journal Article] Long-term follow-up of pediatric Moyamoya disease treated by combined direct-indirect revascularization surgery: Single institute experience with surgical and perioperative management.2016
- Author(s)
  Rashad S, Fujimura M, Niizuma K, Endo H, Tominaga T.
- Journal Title
  
  Neurosurg Rev
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462150
[Journal Article] Prediction of the initiation of cerebral aneurysms2016
- Author(s)
  Kuniyasu Niizuma, Takanobu Yagi, Shin-ichiro Sugiyama, Atsuhiro Nakagawa, and Teiji Tominaga
- Journal Title
  
  The 2nd International Symposium on Multidisciplinary Computational Anatomy
  
  Volume: -
- Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01102
[Journal Article] Transient middle cerebral artery occlusion in mice induces neuronal expression of RNF213, a susceptibility gene for moyamoya disease.2016
- Author(s)
  Sato-Maeda M, Fujimura M, Kanoke A, Morita-Fujimura Y, Niizuma K, Tominaga T.
- Journal Title
  
  Brain Res
  
  Volume: 1630 Pages: 50-55
- DOI
  10.1016/j.brainres.2015.10.055
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462150
[Journal Article] Quantitative analysis of early postoperative cerebral blood flow contributes to the prediction and diagnosis of cerebral hyperperfusion syndrome after revascularization surgery for moyamoya disease.2015
- Author(s)
  FUJIMURA M, Niizuma K, Endo H, Sato K, Inoue T, Shimizu H, Tominaga T
- Journal Title
  
  Neurological research
  
  Volume: 37 Pages: 131-138
- DOI
  10.1179/1743132814y.0000000432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462150, KAKENHI-PROJECT-15K10289
[Journal Article] もやもや病に対する血行再建術後・過灌流に対するミノサイクリンを用いた周術期管理の現状と問題点.2015
- Author(s)
  藤村幹、新妻邦泰、遠藤英徳、佐藤健一、井上敬、冨永悌二.
- Journal Title
  
  脳卒中の外科
  
  Volume: 43 Pages: 136-140
- NAID
  130005072756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462150
[Journal Article] Temporal profile of the vascular anatomy evaluated by 9.4-tesla magnetic resonance angiography and histological analysis in mice with the R4859K mutation of RNF213, the susceptibility gene for moyamoya disease.2015
- Author(s)
  Kanoke A, Fujimura M, Niizuma K, Ito A, Sakata H, Sato-Maeda M, Morita-Fujimura Y, Kure S, and Tominaga T.
- Journal Title
  
  Brain Res.
  
  Volume: 1624 Pages: 497-505
- DOI
  10.1016/j.brainres.2015.07.039
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462150, KAKENHI-PROJECT-15K15385, KAKENHI-PROJECT-15H04871
[Journal Article] Enhanced post-ischemic angiogenesis in mice lacking RNF213; a susceptibility gene for moyamoya disease2015
- Author(s)
  Ito A, Fujimura M, Niizuma K, Kanoke A, Sakata H, Morita-Fujimura Y, Kikuchi A, Kure S, Tominaga T.
- Journal Title
  
  Brain Res.
  
  Volume: 16 Pages: 310-320
- DOI
  10.1016/j.brainres.2014.11.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670470, KAKENHI-PROJECT-26462150, KAKENHI-PROJECT-15K15385, KAKENHI-PROJECT-15H04871
[Journal Article] Genetics and Biomarkers of Moyamoya Disease: Significance of RNF213 as a susceptibility gene2014
- Author(s)
  FUJIMURA M, Sonobe S, Nishijima Y, Niizuma K, Sakata H, Kure S, Tominaga T
- Journal Title
  
  J Stroke
  
  Volume: 16 Pages: 65-72
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462150
[Journal Article] Temporal profile of the vascular anatomy evaluated by 9.4-tesla magnetic resonance angiography and histopathological analysis in mice lacking RNF213; a susceptibility gene for moyamoya disease2014
- Author(s)
  Sonobe S, Fujimura M, Niizuma K, Nishijima Y, Ito A, Shimizu H, Kikuchi A, Arai-Ichinoi N, Kure S, T ominaga T
- Journal Title
  
  Br ain Res
  
  Volume: 1552 Pages: 64-71
- DOI
  10.1016/j.brainres.2014.01.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390267, KAKENHI-PROJECT-23390268, KAKENHI-PROJECT-24659486, KAKENHI-PROJECT-24659642, KAKENHI-PROJECT-25670470, KAKENHI-PROJECT-26462150
[Journal Article] 脳動脈瘤壁の硬化性変化2014
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、松本康史、冨永悌二
- Journal Title
  
  脳神経外科速報
  
  Volume: 24 Pages: 640-643
- Data Source
  KAKENHI-PROJECT-25713051
[Journal Article] Increased vascular MMP-9 in mice lacking RNF213; moyamoya disease susceptibility gene2014
- Author(s)
  Sonobe S, Fujimura M, Niizuma K, Fujimura T, Furudate S, Nishijima Y, Kure S, Tominaga T.
- Journal Title
  
  Neuroreport
  
  Volume: 1552 Pages: 1442-1446
- DOI
  10.1097/wnr.0000000000000289
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670470, KAKENHI-PROJECT-26462150
[Journal Article] Relative residence time prolongation in intracranial aneurysms: a possible association with atherosclerosis.2013
- Author(s)
  Sugiyama S, Niizuma K, Nakayama T, Shimizu H, Endo H, Inoue T, Fujimura M, Ohta M, Takahashi A, Tominaga T.
- Journal Title
  
  Neurosurgery
  
  Volume: 73 Pages: 767-776
- DOI
  10.1227/neu.0000000000000096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] Muse細胞を用いた脳梗塞再生治療2019
- Author(s)
  新妻邦泰
- Organizer
  第44回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01583
[Presentation] An experimental model of hyperperfusion following chronic cerebral ischemia in rats: effect of estrogen deficiency and hypertension.2019
- Author(s)
  Junya Hatakeyama, Yosuke Furuyama, Kuniyasu Niizuma, Teiji Tominaga, Hiroaki Shimizu
- Organizer
  BRAIN & BRAIN PET 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08934
[Presentation] Muse Cell Treatment for Cerebral Ischemia2018
- Author(s)
  Niizuma K、Tominaga T
- Organizer
  Pan Pacific Symposium on Stem Cells and Cancer Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01583
[Presentation] コンピュータを用いた脳動脈瘤の可視化と定量化2018
- Author(s)
  杉山慎一郎　新妻邦泰　冨永悌二　ほか
- Organizer
  一般社団法人日本脳神経外科学会　第77回学術総会
- Data Source
  KAKENHI-PROJECT-18K08961
[Presentation] Muse細胞による脳梗塞治療2018
- Author(s)
  新妻邦泰　冨永悌二
- Organizer
  Stroke2018
- Invited
- Data Source
  KAKENHI-PROJECT-17H01583
[Presentation] MUSE細胞2018
- Author(s)
  新妻邦泰
- Organizer
  第2回日本神経細胞治療研究会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01583
[Presentation] Muse 細胞による脳梗塞治療2018
- Author(s)
  新妻邦泰
- Organizer
  日本脳神経外科学会第77回総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01583
[Presentation] もやもや病に対する直接間接複合血行再建術：頭蓋形成における生体性吸収性プレート併用法の長期成績2017
- Author(s)
  藤村幹，遠藤英徳，新妻邦泰，坂田洋之，冨永悌二
- Organizer
  第９回日本整容脳神経外科研究会（甲府）
- Data Source
  KAKENHI-PROJECT-17K10815
[Presentation] Current status and limitation of the basic research of moyamoya disease using RNF213 mutant mice; Prospect for the future clinical application2017
- Author(s)
  FUJIMURA M, Niizuma K, Kanoke A, Fujimura T, Kure S, Tominaga T
- Organizer
  第７６回日本脳神経外科学会　学術総会（名古屋）
- Data Source
  KAKENHI-PROJECT-17K10815
[Presentation] Development of a New Thrombolytic Agent and Stem Cell Therapy for Cerebral Ischemia2017
- Author(s)
  Niizuma K、Tominaga T
- Organizer
  Ralph L. Nachman Vascular and Biology Seminar Series at Weill Cornell Medical College
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01583
[Presentation] Prediction of the initiation of cerebral aneurysms2016
- Author(s)
  Kuniyasu Niizuma, Takanobu Yagi, Shin-ichiro Sugiyama, Atsuhiro Nakagawa, and Teiji Tominaga
- Organizer
  The 2nd International Symposium on Multidisciplinary Computational Anatomy
- Place of Presentation
  Nagoya
- Year and Date
  2016-02-12
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01102
[Presentation] 脳動脈瘤のCFD2016
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、佐藤健一、藤村幹、松本康史、冨永悌二
- Organizer
  第9回脳血管手術研究会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-26282141
[Presentation] The CFD rupture challenge 2013: Prediction of rupture status in intracranial aneurysms2016
- Author(s)
  杉山慎一郎, 新妻邦泰, 遠藤英徳, 佐藤健一, 松本康史, 船本健一, 太田信, 冨永悌二
- Organizer
  第38回日本脳神経CI学会
- Place of Presentation
  名古屋
- Year and Date
  2016-02-13
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] Bifurcation configuration as a criterion affecting risk of aneurysm rupture in Basilar artery aneurysms2016
- Author(s)
  Sherif Rashad, Shin-ichiro Sugiyama, Kuniyasu Niizuma, Kenichi Sato, Hidenori Endo, Yasushi Matsumoto, Miki Fujimura, Teiji Tominaga
- Organizer
  European congress on computational methods in applied sciences and engineering
- Place of Presentation
  Greece
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] もやもや病の病態解明：もやもや病疾患感受性遺伝子RNF213遺伝子変異マウスを用いた検討.2015
- Author(s)
  藤村幹、新妻邦泰、園部真也、伊藤明、鹿毛淳史、呉繁夫、冨永悌二.
- Organizer
  日本脳神経外科学会第74回学術総会.
- Place of Presentation
  札幌（ロイトン札幌）
- Year and Date
  2015-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-26462150
[Presentation] Outcome of revascularization surgery for elderly patients with moyamoya disease over the age of 60 years: Single institute experience.2015
- Author(s)
  Fujimura M, Niizuma K, Endo H, Sakata H, Tominaga T.
- Organizer
  4th International Moyamoya Meeting.
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462150
[Presentation] 脳疾患領域におけるComputational Fluid Dynamics：最新の知見2015
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、佐藤健一、藤村幹、松本康史、冨永悌二
- Organizer
  2015-02-25_SENDAI 脳・心血管疾患 JOINT Symposium 2015
- Place of Presentation
  江陽グランドホテル（宮城県仙台市）
- Year and Date
  2015-02-25
- Invited
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] Prophylactic blood pressure lowering with intravenous minocycline administration as secure and effective postoperative management after revascularization surgery for moyamoya disease.2015
- Author(s)
  Fujimura M, Niizuma K, Endo H, Sakata H, Tominaga T.
- Organizer
  15th Interim Meeting of the World Federation of Neurological Societies.
- Place of Presentation
  Rome, Italy
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462150
[Presentation] 脳疾患領域におけるComputational Fluid Dynamics：最新の知見2015
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、佐藤健一、藤村幹、松本康史、冨永悌二
- Organizer
  SENDAI 脳・心血管疾患 JOINT Symposium 2015
- Place of Presentation
  仙台
- Year and Date
  2015-02-25
- Invited
- Data Source
  KAKENHI-PROJECT-26282141
[Presentation] 脳動脈瘤に対する数値流体力学的アプローチ2014
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、清水宏明、藤村幹、井上敬、近藤竜史、松本康史、船本健一、冨永悌二
- Organizer
  第43回日本脳卒中の外科学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] CFD解析による脳動脈瘤壁性状の予測2013
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、清水宏明、近藤竜史、松本康史、長嶺義秀、藤原悟、冨永悌二
- Organizer
  第22回日本脳ドック学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] 破裂瘤の治療後早期に破裂した前交通動脈瘤の一例　　ー血行力学的変化の検討ー2013
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、鈴木一郎、近藤竜史、松本康史、冨永悌二
- Organizer
  第29回日本脳神経血管内治療学会学術総会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] Stagnant Blood Flow in Intracranial Aneurysms2013
- Author(s)
  Shin-ichiro Sugiyama, Kuniyasu Niizuma, Kenichi Funamoto, Toshio Nakayama, TeijiTominaga
- Organizer
  ICBME 2013
- Place of Presentation
  Singapore, Singapore
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] A Case of Anterior Communicating Artery Aneurysm Ruptured after the Treatment of Another Ruptured Aneurysm
- Author(s)
  Niizuma K, Sugiyama S, Endo H, Sato K, Matsumoto Y, Fujimura M, Tominaga T
- Organizer
  Asia Pacific Stroke Conference 2014
- Place of Presentation
  台北（台湾）
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25713051
[Presentation] 破裂瘤の治療後早期に破裂した前交通動脈瘤の一例　　ー血行力学的変化の検討ー
- Author(s)
  新妻邦泰、杉山慎一郎、遠藤英徳、佐藤健一、松本康史、藤村幹、冨永悌二
- Organizer
  第26回日本脳循環代謝学会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25713051

1. Tominaga Teiji (00217548)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. SUGIYAMA SHIN-ICHIRO (30623152)

# of Collaborated Projects: 7 results

# of Collaborated Products: 15 results
3. Miki Fujimura (00361098)

# of Collaborated Projects: 6 results

# of Collaborated Products: 25 results
4. 坂田洋之 (80722305)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
5. NAKAGAWA ATSUHIRO (10447162)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
6. FUNAMOTO KENICHI (70451630)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
7. ENDO Hidenori (40723458)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
8. Endo Toshiki (00535370)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 伊藤明 (90867863)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. WASHIO TOSHIKATSU (40358370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ARAFUNE TATSUHIKO (50376597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. Shimizu Hiroaki (20506638)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. 麦倉俊司 (20375017)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. HAYASE TOSHIYUKI (30135313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OHTA MAKOTO (20400418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. Saito Ryuta (10400243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Saito Atsushi (60375053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKAI Masaaki (20431603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大田英揮 (40586905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 出沢真理 (50272323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 後藤昌史 (50400453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 井上智夫 (60791449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 臼杵豊展 (50514535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 大沢伸一郎 (00813693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 西嶌泰生 (90816307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Rashad Sherif (00824088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 針生新也 (90866120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 園部真也 (30869079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. INOUE Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 富永悌二

# of Collaborated Projects: 0 results

# of Collaborated Products: 33 results
31. 三島英換

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 呉繁夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
33. 藤村卓

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
34. 井川俊太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NIIZUMA KUNIYASU 新妻 邦泰

Niizuma Kuniyasu 新妻 邦泰

Research Projects

Research Products

Co-Researchers

Development of Muse cell therapy for dementiaPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

くも膜下出血後早期脳損傷の軽減をめざして：エダラボンのドラッグリポジショニングOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

S1PR1シグナル制御による脳血液関門保護を介したくも膜下出血の新規治療法開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シロスタゾールを用いたもやもや病における内因性幹細胞賦活と血管新生促進療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of latent imaging findings in healthy subjects with moyamoya disease susceptibility gene RNF213 polymorphism using artificial intelligenceOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Muse細胞を用いた脊髄損傷に対する新しい細胞移植治療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エラスチン架橋アミノ酸に着目したもやもや病バイオマーカー診断法の確立Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規慢性脳虚血および脳血管内皮機能障害モデルの開発と血流再建後過灌流機序の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Muse細胞を用いたてんかん原性治癒手法の確立Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

未破裂脳動脈瘤の増大に決定的な役割を果たす血行力学的因子の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

重症型もやもや病に対する多能性幹細胞Museを用いた血管新生療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Platform for regenerative therapy of central nervous system using Muse cellsOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of risk evaluation system of cerebral aneurysms based on the computational fluid dynamicsPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

NIIZUMA KUNIYASU 新妻邦泰

Niizuma Kuniyasu 新妻邦泰

正常から病態へ　～脳動脈瘤の発生に関する多元計算解剖学的アプローチ～Principal Investigator