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Yoshida Hideki  吉田 秀樹

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Yoshida HIdeki  吉田 秀樹

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Researcher Number 10643546
Other IDs
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help 2020 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 助教
2019: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教
2014 – 2015: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / 0901:Oncology and related fields / Pediatrics
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
腫瘍溶解性アデノウイルス / CAR-T細胞療法 / 横紋筋肉腫 / 小児固形腫瘍 / WT1 / 遺伝子改変アデノウイルスベクター / CD19 / CAR-T / プロモーター / 遺伝子改変キメラ受容体T細胞 … More / 腫瘍溶解アデノウイルス / 共刺激因子 / 免疫学的疲弊 / BCL2阻害剤 / ABT-737 / ステロイド抵抗性 / ABT737 / BCL2 / MEF2C / ETP-ALL / T-ALL … More
Except Principal Investigator
横紋筋肉腫 / 神経芽腫 / エクソソーム / 腫瘍溶解性ウイルス / 小児がん / Myostatin / PAX3-FOXO1 / 間葉系間質細胞 / 融合遺伝子 / FOXO1 / PLAGL1 / マイクロRNA / 稀少疾患 / 体液診断 / ラブドイド腫瘍 / 小児腫瘍 / miRNA / 分化 / T-reg / 制御性T細胞 / エフェクターサイトカイン / CAR-T / プロモーター制御 / CAR-T療法 / 腫瘍溶解性アデノウイルス / 患者腫瘍組織移植モデル / 鶏卵漿尿膜法 / 鶏卵漿尿膜 / CAMアッセイ / オフターゲット / 遺伝子改変T細胞 / 腫瘍微小環境 / 免疫疲弊 / 固形腫瘍 / CAR-T細胞 Less
  • Research Projects

    (12 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (12 People)
  •  Development of gene cell therapy using mesenchymal stromal cells for neuroblastoma

    • Principal Investigator
      家原 知子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel gene therapy for rhabdomyosarcoma

    • Principal Investigator
      菊地 顕
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Novel therapeutic strategy for pediatric malignant solid tumors using WT1 promoter-regulated oncovirusPrincipal Investigator

    • Principal Investigator
      吉田 秀樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Characterization of PLAGL1-FOXO1 fusion gene in alveolar rhabdomyosarcoma

    • Principal Investigator
      宮地 充
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Liquid biopsy for Rhabdoid tumor by Exoxomal-microRNAs in blood and other body fluids

    • Principal Investigator
      勝見 良樹
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of combinatorial CAR-T cell therapy improving immunosupressive tumor microenvironment

    • Principal Investigator
      Yagyu Shigeki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Gene and cell therapy combining CD19-expressing adenovirus and CD19 CAR-T cellsPrincipal Investigator

    • Principal Investigator
      Yoshida Hideki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  In ovo chorioallantoic membrane assay as a xenograft model for pediatric rhabdomyosarcoma

    • Principal Investigator
      Kikuchi Ken
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of CAR-T cell therapy complementary system for rhabdomyosarcoma using oncolytic virus

    • Principal Investigator
      Hosoi Hajime
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Examination of novel prognostic markers related to spontaneous regression and differentiation of neuroblastoma

    • Principal Investigator
      Iehara Tomoko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of a co-stimulator-expressing oncolytic virus that contributes to the improvement of " immunological exhaustion" of CAR-T cellsPrincipal Investigator

    • Principal Investigator
      Yoshida HIdeki
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of new therapeutic strategy for ETP-ALLPrincipal Investigator

    • Principal Investigator
      Yoshida Hideki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2023 2022 2015

All Journal Article Presentation

  • [Journal Article] <i>In?ovo</i> chorioallantoic membrane assay as a xenograft model for pediatric rhabdomyosarcoma2023

    • Author(s)
      Shoji Chika、Kikuchi Ken、Yoshida Hideki、Miyachi Mitsuru、Yagyu Shigeki、Tsuchiya Kunihiko、Nakaya Takaaki、Hosoi Hajime、Iehara Tomoko
    • Journal Title

      Oncology Reports

      Volume: 49 Issue: 4

    • DOI

      10.3892/or.2023.8513

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08187
  • [Journal Article] Targeting FLT3-specific chimeric antigen receptor T cells for acute lymphoblastic leukemia with KMT2A rearrangement2022

    • Author(s)
      Suematsu Masaya、Yagyu Shigeki、Yoshida Hideki、Osone Shinya、Nakazawa Yozo、Sugita Kanji、Imamura Toshihiko、Iehara Tomoko
    • Journal Title

      Cancer Immunology, Immunotherapy

      Volume: 72 Issue: 4 Pages: 957-968

    • DOI

      10.1007/s00262-022-03303-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07825, KAKENHI-PROJECT-20K07641
  • [Journal Article] BCL2 Inhibitor (ABT-737): A Restorer of Prednisolone Sensitivity in Early T-Cell Precursor-Acute Lymphoblastic Leukemia with High MEF2C Expression?2015

    • Author(s)
      Kawashima-Goto S, Imamura T, Tomoyasu C, Yano M, Yoshida H, Fujiki A, Tamura S, Osone S, Ishida H, Morimoto A, Kuroda H, Hosoi H
    • Journal Title

      PLoS One.

      Volume: 10 Issue: 7 Pages: e0132926-e0132926

    • DOI

      10.1371/journal.pone.0132926

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26860820
  • [Presentation] Identification of the PLAGL1-FOXO1 fusion gene in a case of alveolar rhabdomyosarcoma.2022

    • Author(s)
      Sugitatsu Y,Oya S,Kondo H,Tomida A, Yoshida H,Miyachi M,Kikuchi K, Tsuchiya K, Iehara T
    • Organizer
      第64回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07940
  • 1.  Kikuchi Ken (40453104)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 2 results
  • 2.  Yagyu Shigeki (10572547)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 2 results
  • 3.  Iehara Tomoko (20285266)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 3 results
  • 4.  宮地 充 (40584983)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 5.  Hosoi Hajime (20238744)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  土屋 邦彦 (90381938)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  中屋 隆明 (80271633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  勝見 良樹 (00808496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  松尾 雅文 (10157266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  富田 晃正 (30933022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  IMAMURA Toshihiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  大曽根 眞也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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