Kojima Kaname 小島要

… Alternative Names

Kaname Kojima 小島要

KOJIMA Kaname 小島要

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Researcher Number	10646988
Other IDs
Affiliation (Current)	2025: 東北大学, 東北メディカル・メガバンク機構, 講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 東北大学, 東北メディカル・メガバンク機構, 講師 2014: 東北大学, 東北メディカル・メガバンク機構, 講師 2013: 東北大学, 東北メディカル・メガバンク機構, 助教
Review Section/Research Field	Principal Investigator Basic Section 62010:Life, health and medical informatics-related / Life / Health / Medical informatics / Statistical science Except Principal Investigator Basic Section 53050:Dermatology-related / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Gastroenterology
Keywords	Principal Investigator 深層学習 / 関連解析 / 機序解明 / HLA / AI / アレルギー疾患 / 臨床画像 / 状態空間モデル / 紫外線肌ダメージ / スマートフォン … More / 皮膚がん / 紫外線曝露 / cycleGAN / pix2pix / 敵対的生成ネットワーク / 紫外線写真 / 色素斑 / 肌ダメージ / 予防医療 / ゲノム解析 / SNPアレイ / ハイスループットシークエンサ / 機械学習 / シークエンスデータ解析 / インピュテーション / ハイスループットシークエンサー / 遺伝子型インピューテーション / マイクロサテライト / 遺伝子発現量定量 / 変異コール / 遺伝子制御ネットワーク / 次世代シークエンサ / 遺伝子発現 / 次世代シークエンサー / エピジェネティクス / 細胞内制御ネットワーク … More Except Principal Investigator メラノサイト / GWAS / ゲノムワイド連鎖解析 / 紫外線 / 白斑 / スキンタイプ / Klotho遺伝子 / 遺伝環境因子 / 光干渉断層計(OCT) / アルツハイマー病前臨床期 / 環境因子 / 遺伝因子 / 網膜層厚変化 / 網膜断層画像撮像 / 光干渉断層計 / 網羅的遺伝子発現解析 / 統合解析 / トランスクリプトーム / 分子標的 / 疾患発症経路 / 疾患感受性遺伝子 / ゲノムワイド関連解析 / 原発性胆汁性胆管炎 Less

アレルギー疾患機序解明のためのHLA多型を考慮した解釈可能AIゲノム解析基盤構築Principal Investigator
- Principal Investigator
  
  小島要
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Tohoku University
紫外線感受性核酸多型に基づく尋常性白斑発症予測プログラムの構築
- Principal Investigator
  
  山崎研志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tohoku University
網膜層厚と遺伝環境因子による孤発性晩期発症型アルツハイマー病前臨床期診断法の確立
- Principal Investigator
  
  平良摩紀子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Tohoku University
Establishment of Time Series UV Skin Damage Prediction Methods Based on Deep Learning and Deep State Space ModelsPrincipal Investigator
- Principal Investigator
  
  Kojima Kaname
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Tohoku University
Exhaustive discovery of disease related variants by the construction of integrated analysis methods of microsatellites from genome dataPrincipal Investigator
- Principal Investigator
  
  Kaname Kojima
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  Tohoku University
GWAS-based integrated analysis of PBC to dissect the mechanism of development and progression of primary biliary cholangitis
- Principal Investigator
  
  Nakamura Minoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
Modeling of genes and epigenome intracellular regulatory network and analysis of cellular differentiation mechanismsPrincipal Investigator
- Principal Investigator
  
  KOJIMA Kaname
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Statistical science
- Research Institution
  Tohoku University

All 2023 2021 2020 2018 2017 2015 2014 2013 Other

All Journal Article Presentation Other

[Journal Article] Convolutional neural network-based skin image segmentation model to improve classification of skin diseases in conventional and non-standardized picture images2023
- Author(s)
  Yanagisawa Yuta、Shido Kosuke、Kojima Kaname、Yamasaki Kenshi
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 109 Issue: 1 Pages: 30-36
- DOI
  10.1016/j.jdermsci.2023.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08422
[Journal Article] Facial UV photo imaging for skin pigmentation assessment using conditional generative adversarial networks2021
- Author(s)
  Kojima Kaname、Shido Kosuke、Tamiya Gen、Yamasaki Kenshi、Kinoshita Kengo、Aiba Setsuya
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1213-1213
- DOI
  10.1038/s41598-020-79995-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12058, KAKENHI-PROJECT-19K08765
[Journal Article] A genotype imputation method for de-identified haplotype reference information by using recurrent neural network2020
- Author(s)
  Kojima Kaname、Tadaka Shu、Katsuoka Fumiki、Tamiya Gen、Yamamoto Masayuki、Kinoshita Kengo
- Journal Title
  
  PLOS Computational Biology
  
  Volume: 16 Issue: 10 Pages: e1008207-e1008207
- DOI
  10.1371/journal.pcbi.1008207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12058
[Journal Article] Population-scale whole genome sequencing identifies 271 highly polymorphic short tandem repeats from Japanese population2018
- Author(s)
  Hirata, S., Kojima, K., Misawa, K., Gervais, O., Kawai, Y., and Nagasaki, M.
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 5 Pages: 1-19
- DOI
  10.1016/j.heliyon.2018.e00625
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17590
[Journal Article] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population2018
- Author(s)
  Nishida Nao、Aiba Yoshihiro、Hitomi Yuki、Nagasaki Masao、Tokunaga Katsushi、Nakamura Minoru et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8071-8071
- DOI
  10.1038/s41598-018-26369-6
- NAID
  120006551764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09449, KAKENHI-PROJECT-17K15924, KAKENHI-PROJECT-17H04169
[Journal Article] NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants.2018
- Author(s)
  Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
- Journal Title
  
  Cell Mol Gastroenterol Hepatol
  
  Volume: 7 Issue: 3 Pages: 515-532
- DOI
  10.1016/j.jcmgh.2018.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15924, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-17H04168, KAKENHI-PROJECT-17K09449
[Journal Article] Cathepsin Z variants are associated with progression to end-stage hepatic failure in Japanese patients with primary biliary cholangitis.2017
- Author(s)
  Nishida N, Aiba Y, Kawashima M, Hitomi Y, Kojima K, Komori A, Nagasaki M,Tokunaga K, Nakamura M
- Journal Title
  
  J Hepatol
  
  Volume: 66(1, Suppl)
- Data Source
  KAKENHI-PROJECT-17H04169
[Journal Article] Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis2017
- Author(s)
  Hitomi Yuki、Kojima Kaname、Kawashima Minae、Kawai Yosuke、Nishida Nao、Aiba Yoshihiro、Yasunami Michio、Nagasaki Masao、Nakamura Minoru、Tokunaga Katsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 2904-2904
- DOI
  10.1038/s41598-017-03067-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-15K06908
[Journal Article] Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.2017
- Author(s)
  Kawashima M, Honda M, Nakamura M. et al.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: - Pages: 650-659
- DOI
  10.1093/hmg/ddw406
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26460416, KAKENHI-PROJECT-26460996, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-16K21069, KAKENHI-PROJECT-17H04058, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-16H05283, KAKENHI-PROJECT-15K19357
[Journal Article] HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data2015
- Author(s)
  Naoki Nariai, Kaname Kojima, Sakae Saito, Takahiro Mimori, Yukuto Sato, Yosuke Kawai, Yumi Yamaguchi-Kabata, Jun Yasuda, and Masao Nagasaki
- Journal Title
  
  BMC Genomics
  
  Volume: 16(Suppl 2) Pages: 1-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25730011
[Journal Article] Estimating copy numbers of alleles from population-scale high-throughput sequencing data2015
- Author(s)
  Takahiro Mimori, Naoki Nariai, Kaname Kojima, Yukuto Sato, Yosuke Kawai, Yumi Yamaguchi-Kabata, and Masao Nagasaki
- Journal Title
  
  BMC Bioinformatics
  
  Volume: 16(Suppl 1) Pages: 1-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25730011
[Journal Article] HapMonster: a statistically unified approach for variant calling and haplotyping based on phase-informative reads2014
- Author(s)
  Kaname Kojima, Naoki Nariai, Takahiro Mimori, Yumi Yamaguchi-Kabata, Yukuto Sato, Yosuke Kawai, and Masao Nagasaki
- Journal Title
  
  Lecture Notes in Computer Science
  
  Volume: 8542 Pages: 107-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25730011
[Journal Article] TIGAR2: sensitive and accurate estimation of transcript isoform expression with longer RNA-Seq reads2014
- Author(s)
  Naoki Nariai, Kaname Kojima, Takahiro Mimori, Yukuto Sato, Yosuke Kawai, Yumi Yamaguchi-Kabata, and Masao Nagasaki
- Journal Title
  
  BMC Genomics
  
  Volume: 15(Suppl 9) Pages: 1-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25730011
[Journal Article] SVEM: a structural variant estimation method using multi-mapped reads on breakpoints2014
- Author(s)
  Tomohiko Ohtsuki, Naoki Nariai, Kaname Kojima, Takahiro Mimori, Yukuto Sato, Yosuke Kawai, Yumi Yamaguchi-Kabata, and Masao Nagasaki
- Journal Title
  
  Lecture Notes in Computer Science
  
  Volume: 8542 Pages: 208-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25730011
[Journal Article] A statistical variant calling approach from pedigree information and local haplotyping with phase informative reads2013
- Author(s)
  Kaname Kojima, Naoki Nariai, Takahiro Mimori, Mamoru Takahashi, Yumi Yamaguchi-Kabata, Yukuto Sato, and Masao Nagasaki
- Journal Title
  
  Bioinformatics
  
  Volume: 29 (22) Issue: 22 Pages: 2835-2843
- DOI
  10.1093/bioinformatics/btt503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25730011
[Journal Article] TIGAR : transcript isoform abundance estimation method with gapped alignment of RNA-Seq data by variational Bayesian inference2013
- Author(s)
  Naoki Nariai, Osamu Hirose, Kaname Kojima, Masao Nagasaki
- Journal Title
  
  Bioinformatics
  
  Volume: 29 (18) Issue: 18 Pages: 2292-2299
- DOI
  10.1093/bioinformatics/btt381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24810010, KAKENHI-PROJECT-25730011
[Presentation] 新たなSTR8座位のマルチプレックスPCR法および全ゲノムシークエンスデータ解析によるSTRタイピング2018
- Author(s)
  平田智士、関谷弥生、小島要、三澤計治、Gervais Olivier、人見祐基、河合洋介、徳永勝士、長﨑正朗
- Organizer
  日本DNA多型学会
- Data Source
  KAKENHI-PROJECT-17K17590
[Presentation] Genome-wide Association Studies Identify PRKCB as A Novel Genetic Susceptibility Locus for Primary Biliary Cholangitis in the Japanese Population.2017
- Author(s)
  Nakamura M, Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Komori A, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, PBC consortium in Japan.
- Organizer
  The 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL 2017).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] GWAS polygenic model approach applied to primary biliary cholangitis (PBC) in a Japanese population.2017
- Author(s)
  O. Gervais, Ueno K, Kojima K, Aiba Y, Kawashima M, Kawai Y, Hitomi Y, Tokunaga K, Nakamura M, Nagasaki M.
- Organizer
  ASHG 2017（The 67th Annual Meeting of the American Society of Human Genetics）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.2017
- Author(s)
  Kawashima M, Nishida N, Hitomi Y, Kojima K, Kawai Y, Aiba Y, Nakamura H, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  ASHG 2017（The 67th Annual Meeting of the American Society of Human Genetics）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
- Organizer
  ASHG 2017（The 67th Annual Meeting of the American Society of Human Genetics）.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Statistical methods for analyzing next generation sequencing data2014
- Author(s)
  Kaname Kojima
- Organizer
  International Statistical Symposium CSA-KSS-JSS Special Invited Sessions
- Place of Presentation
  台湾、新竹市、交通大学
- Year and Date
  2014-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-25730011
[Presentation] HapMonster: a Statistically Unified Approach for Variant Calling and Haplotyping Based on Phase-informative Reads2014
- Author(s)
  Kaname Kojima, Naoki Nariai, Takahiro Mimori, Yumi Yamaguchi-Kabata, Yukuto Sato, Yosuke Kawai and Masao Nagasaki
- Organizer
  1st International Conference on Algorithms for Computational Biology
- Place of Presentation
  Tarragona, Spain
- Data Source
  KAKENHI-PROJECT-25730011
[Presentation] Short tandem repeat number estimation from paired-end sequence reads by considering unobserved genealogy of multiple individuals
- Author(s)
  Kaname Kojima, Yosuke Kawai, Naoki Nariai, Takahiro Mimori, Takanori Hasegawa, and Masao Nagasaki
- Organizer
  11th International Symposium on Bioinformatics Research and Applications
- Place of Presentation
  アメリカ合衆国、バージニア州ノーフォーク市、オールドドミニオン大学
- Year and Date
  2015-06-07 – 2015-06-10
- Data Source
  KAKENHI-PROJECT-25730011
[]

1. 山崎研志 (40294798)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. Nakamura Minoru (40217906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 川嶋実苗 (00396706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 人見祐基 (10525819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 下田慎治 (30279319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 安波道郎 (80244127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 平良摩紀子 (60792140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 布施昇男 (10302134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 川崎良 (70301067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 三木篤也 (30437404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田高周 (60815463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 元池育子 (70347178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AIBA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. HIROSE Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 伊東正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 川合覚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kojima Kaname 小島 要

Kaname Kojima 小島 要

KOJIMA Kaname 小島 要

Research Projects

Research Products

Co-Researchers

アレルギー疾患機序解明のためのHLA多型を考慮した解釈可能AIゲノム解析基盤構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

紫外線感受性核酸多型に基づく尋常性白斑発症予測プログラムの構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

網膜層厚と遺伝環境因子による孤発性晩期発症型アルツハイマー病前臨床期診断法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of Time Series UV Skin Damage Prediction Methods Based on Deep Learning and Deep State Space ModelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exhaustive discovery of disease related variants by the construction of integrated analysis methods of microsatellites from genome dataPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GWAS-based integrated analysis of PBC to dissect the mechanism of development and progression of primary biliary cholangitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modeling of genes and epigenome intracellular regulatory network and analysis of cellular differentiation mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Convolutional neural network-based skin image segmentation model to improve classification of skin diseases in conventional and non-standardized picture images2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Facial UV photo imaging for skin pigmentation assessment using conditional generative adversarial networks2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A genotype imputation method for de-identified haplotype reference information by using recurrent neural network2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Population-scale whole genome sequencing identifies 271 highly polymorphic short tandem repeats from Japanese population2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cathepsin Z variants are associated with progression to end-stage hepatic failure in Japanese patients with primary biliary cholangitis.2017

Kojima Kaname 小島要

Kaname Kojima 小島要

KOJIMA Kaname 小島要