NOMURA SEITARO 野村征太郎

… Alternative Names

Nomura Seitaro 野村征太郎

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Researcher Number	10722118
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 特任准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 東京大学, 医学部附属病院, 特任准教授 2016 – 2023: 東京大学, 医学部附属病院, 特任助教 2015 – 2016: 東京大学, 医学部附属病院, 助教 2014: 東京大学, 医学部附属病院, 研究員
Review Section/Research Field	Principal Investigator Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related / Basic Section 55030:Cardiovascular surgery-related / Cardiovascular medicine / Biological Sciences / Basic Section 53040:Nephrology-related / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator 心不全 / 創薬 / 機序解明 / マルチオミックス解析 / 心房細動 / ゲノム編集 / シングルセル生物学 / 心筋リプログラミング / シングルセル解析 / 遺伝子発現 … More / １細胞解析 / 循環器 / 循環器内科学 / 分子心臓病学 / ゲノム科学 / 分子心臓学 … More Except Principal Investigator 心不全 / シングルセル解析 / エピゲノム / 分子心臓病学 / コンソーシアム研究 / デジタル情報 / ゲノム・オミックス解析 / 循環器疾患 / 国際連携 / Cardiac surgery / Etiological Analysis / NG sequencer / Whole genome sequence / TAPVC / 原因遺伝子 / 肺静脈狭窄予防 / トリオ解析 / 全ゲノム解析 / 総肺静脈還流異常症 / COVID-19 関連腎症 / 糖尿病性腎臓病 / Spatial 解析システム / CODEX / 腎疾患 / 微小環境マルチプレックス解析システム / マルチプレックス免疫染色 / 拡張相肥大型心筋症 / snRNA-Seq / 肥大型心筋症 / ポイントオブケア / リキッドアセスメント / 難治性創傷 / 細胞老化 / 創傷ドレッシング / 看護理工学 / ゲノム解析 / 心臓手術 / 肺静脈狭窄 / 総肺静脈環流異常症 / シグナル伝達 / 老化 / DNA損傷 / シグナルネットワーク / ミトコンドリア / マイトファジー / ミトコンドリア生合成 / 循環器内科学 / イメージング解析 / 遺伝子発現 / 心筋細胞 / 精密医療 / バイオインフォマティクス / イメージング / シングルセルRNA-seq / 時空間的遺伝子発現 / シングルセルRNA-seq解析 / 心筋細胞不均一性 / シングルセル生物学 / 不均一性 / 心筋細胞分化 / ゲノム / 循環器 / 転写制御 / 遺伝子制御 / 分子心臓学 Less

プレシジョン循環器治療学の創成Principal Investigator
- Principal Investigator
  
  野村征太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
Investigation of Cardiac Epigenomic Circuit in the Development of Heart Failure and Identification of Potential Therapeutic Targets
- Principal Investigator
  
  桑原宏一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Shinshu University
Exploration of Therapeutic Targets for the Prevention of Pulmonary Vein Stenosis Following Surgical Repair of Total Anomalous Pulmonary Venous Connection
- Principal Investigator
  
  枝木大治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Okayama University
International Cardiovascular Digital Omics Consortium
- Principal Investigator
  
  小室一成
- Project Period (FY)
  2024 – 2030
- Research Category
  
  Fund for the Promotion of Joint International Research (International Leading Research )
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Selective wound healing senolytics targeting senescent cells in wound exudate
- Principal Investigator
  
  仲上豪二朗
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
心筋生検検体を用いたシングル核RNA-Seqと空間的解析による肥大型心筋症の病態解明
- Principal Investigator
  
  吉田昌平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa University
New evaluation method for renal diseases using a microenvironmental multiplexing analysis system
- Principal Investigator
  
  片桐大輔
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  National Center for Global Health and Medicine
Cause analysis of TAPVC generation using whole-genome analysis by next-generation sequencer
- Principal Investigator
  
  辻龍典
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Iwate Medical University
Integrative understanding of cardiac system architecture and its regulationPrincipal Investigator
- Principal Investigator
  
  野村征太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
非分裂細胞である心筋細胞のDNA損傷と老化による心不全発症機序の解明
- Principal Investigator
  
  小室一成
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
Single-cell omics analysis to develop the therapy for heart failure via cardiomyocyte reprogrammingPrincipal Investigator
- Principal Investigator
  
  Nomura Seitaro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
Comprehensive analysis to uncover molecular network between mitochondria and nucleus underlying mitochondrial homeostasis
- Principal Investigator
  
  Hoshino Atsushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Cardiomyocyte heterogeneity in heart failure
- Principal Investigator
  
  Komuro Issei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  The University of Tokyo
Cardiomyocyte herogeneity in heart failurePrincipal Investigator
- Principal Investigator
  
  Nomura Seitaro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  The University of Tokyo
Epigenome analysis in cardiomyocyte differentiation and failure
- Principal Investigator
  
  Komuro Issei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book Patent Other

[Book] 循環器疾患最新の治療2022-20232022
- Author(s)
  野村征太郎・小室一成
- Total Pages
  520
- Publisher
  南江堂
- ISBN
  9784524229956
- Data Source
  KAKENHI-PROJECT-19H03649
[Book] もっとよくわかる！循環器学と精密医療2020
- Author(s)
  野村征太郎
- Total Pages
  204
- Publisher
  羊土社
- ISBN
  9784758122085
- Data Source
  KAKENHI-PROJECT-19H03649
[Book] 心不全治療薬の考え方，使い方「心筋ミオシン活性化薬」2019
- Author(s)
  野村征太郎
- Total Pages
  298
- Publisher
  中外医学社
- ISBN
  9784498136588
- Data Source
  KAKENHI-PROJECT-19H03649
[Book] 循環器内科第86巻第6号「心筋症の遺伝子治療」2019
- Author(s)
  野村征太郎
- Total Pages
  150
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PROJECT-19H03649
[Book] 循環器ジャーナル 2020年01月号 (通常号) ( Vol.68 No.1) 特集　U40世代が描く心不全診療の現状と未来－基礎研究を識り，臨床を素心深考する「がん治療関連性心血管障害の予後予測因子はありますか？ゲノム研究はどこまで進んでいるの？」2019
- Author(s)
  野村征太郎
- Total Pages
  184
- Publisher
  医学書院
- ISBN
  9784260029605
- Data Source
  KAKENHI-PROJECT-19H03649
[Book] 実験医学増刊 Vol.37 No.20 シングルセルゲノミクス組織の機能、病態が1細胞レベルで見えてきた！「心筋シングルセル解析による病態解明から臨床応用」2019
- Author(s)
  野村征太郎、油谷浩幸
- Total Pages
  219
- Publisher
  羊土社
- ISBN
  9784758103831
- Data Source
  KAKENHI-PROJECT-19H03649
[Book] Heart View 2019年12月号 Vol.23 No.13 心筋症のいまを識る！「遺伝子検査を心筋症・循環器診療にどう活かすか？」2019
- Author(s)
  野村征太郎
- Total Pages
  120
- Publisher
  文光堂
- ISBN
- Data Source
  KAKENHI-PROJECT-19H03649
[Journal Article] TEAD1 trapping by the Q353R?Lamin A/C causes dilated cardiomyopathy2023
- Author(s)
  Yamada S、et al.,
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 15 Pages: 1-1
- DOI
  10.1126/sciadv.ade7047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06809, KAKENHI-PROJECT-21K16082, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21K16047, KAKENHI-PROJECT-22H00471, KAKENHI-PLANNED-19H05744, KAKENHI-PLANNED-21H05254, KAKENHI-PLANNED-22H05125, KAKENHI-PROJECT-22H00320, KAKENHI-PROJECT-23K24057
[Journal Article] Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction2023
- Author(s)
  Miyazawa Kazuo、Ito Kaoru、Ito Masamichi、Zou Zhaonan、Kubota Masayuki、Nomura Seitaro、Matsunaga Hiroshi、Koyama Satoshi、Ieki Hirotaka、et al.
- Journal Title
  
  Nature Genetics
  
  Volume: 55 Issue: 2 Pages: 187-197
- DOI
  10.1038/s41588-022-01284-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16128, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02919, KAKENHI-PROJECT-20J01343, KAKENHI-PROJECT-22KJ1890, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-22KJ3142, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-23K24602
[Journal Article] LMNA Mutations and Right Heart Failure in Patients With Cardiomyopathy and With Left Ventricular Assist Devices2023
- Author(s)
  Yamada T, Nomura S, Amiya E, Katoh M, Inoue S, Hatsuse S, Fujita K, Ito M, Fujita T, Bujo C, Tsuji M, Ishida J, Ko T, Yamada S, Katagiri M, Sassa T, Kinoshita O, Nawata K, Tobita T, Satoh M, Ishiwata J, Daimon M, Tatsuno K, Fukuda S, Kashimura T, Minamino T, Hatano M, Ono M, Aburatani H, Komuro I.
- Journal Title
  
  Journal of Cardiac Failure
  
  Volume: 29 Issue: 5 Pages: 855-857
- DOI
  10.1016/j.cardfail.2023.01.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K16047, KAKENHI-PROJECT-21K08047, KAKENHI-PROJECT-22H00471
[Journal Article] Novel AGL variants in a patient with glycogen storage disease type IIIb and pulmonary hypertension caused by pulmonary veno-occlusive disease: A case report2023
- Author(s)
  Shindo Akito、Ueda Kazutaka、Minatsuki Shun、Nakayama Yukiteru、Hatsuse Satoshi、Fujita Kanna、Nomura Seitaro、Hatano Masaru、Takeda Norifumi、Akazawa Hiroshi、Komuro Issei
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 14 Pages: 1148067-1148067
- DOI
  10.3389/fgene.2023.1148067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-21H02908
[Journal Article] Precision and genomic medicine for dilated and hypertrophic cardiomyopathy2023
- Author(s)
  Nomura Seitaro、Ono Minoru
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 10 Pages: 1137498-1137498
- DOI
  10.3389/fcvm.2023.1137498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471
[Journal Article] Manipulating Cardiomyocyte Plasticity for Heart Regeneration2022
- Author(s)
  Ko Toshiyuki、Nomura Seitaro
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 929256-929256
- DOI
  10.3389/fcell.2022.929256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471
[Journal Article] Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling2022
- Author(s)
  Adachi Yusuke、Ueda Kazutaka、Nomura Seitaro、Ito Kaoru、Katoh Manami、Katagiri Mikako、Yamada Shintaro、Hashimoto Masaki、Zhai Bowen、Numata Genri、Otani Akira、Hinata Munetoshi、Hiraike Yuta、Waki Hironori、Takeda Norifumi、Morita Hiroyuki、Ushiku Tetsuo、Yamauchi Toshimasa、Takimoto Eiki、Komuro Issei
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 5117-5117
- DOI
  10.1038/s41467-022-32658-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19K17976, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-21H02908
[Journal Article] Dysregulation of DNA Methylation in the Aryl-Hydrocarbon Receptor Repressor (<i>AHRR</i>) Gene2022
- Author(s)
  Nomura S, Morita H.
- Journal Title
  
  Circ J
  
  Volume: 86 Issue: 6 Pages: 993-994
- DOI
  10.1253/circj.CJ-22-0111
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2022-05-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471
[Journal Article] Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure2022
- Author(s)
  Shun Nakamura, Genri Numata, Toshihiro Yamaguchi, Hiroyuki Tokiwa, Yasutomi Higashikuni, Seitaro Nomura, Tetsuo Sasano, Eiki Takimoto, Issei Komuro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 637 Pages: 247-253
- DOI
  10.1016/j.bbrc.2022.11.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08098, KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-22KJ1202
[Journal Article] Functional Evaluation of Human Bioengineered Cardiac Tissue Using iPS Cells Derived from a Patient with Lamin Variant Dilated Cardiomyopathy2022
- Author(s)
  Miura K, Matsuura K, Yamasaki Itoyama Y, Sasaki D, Takada T, Furutani Y, Hayama E, Ito M, Nomura S, Morita H, Toyoda M, Umezawa A, Onoue K, Saito Y, Aburatani H, Nakanishi T, Hagiwara N, Komuro I, Shimizu T.
- Journal Title
  
  Int. Heart J.
  
  Volume: 63 Issue: 2 Pages: 338-346
- DOI
  10.1536/ihj.21-790
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2022-03-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16082, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis2022
- Author(s)
  Ko Toshiyuki、Nomura Seitaro、Yamada Shintaro、Fujita Kanna、Fujita Takanori、Satoh Masahiro、Oka Chio、Katoh Manami、Ito Masamichi、Amiya Eisuke、Hatano Masaru、Kinoshita Osamu、Nawata Kan、Abe Hiroyuki、Ushiku Tetsuo、Ono Minoru、Ikeuchi Masashi、Morita Hiroyuki、Aburatani Hiroyuki、Komuro Issei
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 3275-3275
- DOI
  10.1038/s41467-022-30630-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16047, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471
[Journal Article] Single-Cell Analysis Revealed the Role of CD8+ Effector T Cells in Preventing Cardioprotective Macrophage Differentiation in the Early Phase of Heart Failure2021
- Author(s)
  Komai Kyoko、Ito Minako、Nomura Seitaro、Shichino Shigeyuki、Katoh Manami、Yamada Shintaro、Ko Toshiyuki、Iizuka-Koga Mana、Nakatsukasa Hiroko、Yoshimura Akihiko
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 763647-763647
- DOI
  10.3389/fimmu.2021.763647
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08891, KAKENHI-PROJECT-18K15129, KAKENHI-PROJECT-19K17587, KAKENHI-PUBLICLY-21H00432, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21H02719, KAKENHI-PROJECT-19J40137, KAKENHI-PROJECT-20K07541, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] Single-cell genomics to understand disease pathogenesis2021
- Author(s)
  Nomura S.
- Journal Title
  
  J Hum Genet.
  
  Volume: 66 Issue: 1 Pages: 75-84
- DOI
  10.1038/s10038-020-00844-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649
[Journal Article] Precision medicine for heart failure based on molecular mechanisms: The 2019 ISHR Research Achievement Award Lecture2021
- Author(s)
  Nomura S, Komuro I.
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 152 Pages: 29-39
- DOI
  10.1016/j.yjmcc.2020.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649
[Journal Article] New Vision, Mission, and Values of the Japanese Circulation Society2021
- Author(s)
  Ishida M, Matsumoto C, Kida K, Fukuda M, Kagiyama N, Kusunose K, Matsumoto S, Nomura S, Okumura T, Shiono Y, Taniguchi T, Mizuno A, Kishi T, Node K, Komuro I, Hirata KI; Directors of the Japanese Circulation Society.
- Journal Title
  
  Circ J
  
  Volume: 85 Issue: 12 Pages: 2248-2251
- DOI
  10.1253/circj.CJ-21-0822
- NAID
  130008119954
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2021-11-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury2021
- Author(s)
  Hasegawa S, Inoue T, Nakamura Y, Fukaya D, Uni R, Wu CH, Fujii R, Peerapanyasut W, Taguchi A, Kohro T, Yamada S, Katagiri M, Ko T, Nomura S, Nakanishi Ozeki A, Susaki EA, Ueda HR, Akimitsu N, Wada Y, Komuro I, Nangaku M, Inagi R.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: - Issue: 7 Pages: 1599-1615
- DOI
  10.1681/asn.2020121723
- NAID
  120007174517
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19J11928, KAKENHI-PROJECT-19K22679, KAKENHI-PROJECT-19K17587, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-21H05045
[Journal Article] Recent Progress in Cardiovascular Research Involving Single-Cell Omics Approaches.2021
- Author(s)
  Dai Z, Nomura S.
- Journal Title
  
  Front Cardiovasc Med.
  
  Volume: 8 Pages: 783398-783398
- DOI
  10.3389/fcvm.2021.783398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] CXCR7 ameliorates myocardial infarction as a β arrestin-biased receptor2021
- Author(s)
  Ishizuka et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 3426-3426
- DOI
  10.1038/s41598-021-83022-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08510, KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-19K17587, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19J13042, KAKENHI-PROJECT-19K17667
[Journal Article] Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice2021
- Author(s)
  Fujiwara Takayuki、Takeda Norifumi、Hara Hironori、Ishii Satoshi、Numata Genri、Tokiwa Hiroyuki、Maemura Sonoko、Suzuki Takaaki、Takiguchi Hiroshi、Kubota Yoshiaki、Seo Kinya、Sakata Asuka、Nomura Seitaro、Hatano Masaru、Ueda Kazutaka、Komuro Issei
- Journal Title
  
  Circulation
  
  Volume: 144 Issue: 17 Pages: 1452-1455
- DOI
  10.1161/circulationaha.121.056219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08096, KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21K16110, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-21H02908
[Journal Article] Recent Findings Related to Cardiomyopathy and Genetics.2021
- Author(s)
  Yamada T, Nomura S.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22 Issue: 22 Pages: 12522-12522
- DOI
  10.3390/ijms222212522
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] Prediction of single-cell mechanisms for disease progression in hypertrophic remodelling by a trans-omics approach2021
- Author(s)
  Hamano M, Nomura S, Iida M, Komuro I, Yamanishi Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Issue: 1 Pages: 8112-8112
- DOI
  10.1038/s41598-021-86821-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21H05045
[Journal Article] Single-Cardiomyocyte RNA Sequencing to Dissect the Molecular Pathophysiology of the Heart.2021
- Author(s)
  Katoh M, Nomura S, Yamada S, Aburatani H, Komuro I.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2320 Pages: 183-192
- DOI
  10.1007/978-1-0716-1484-6_18
- ISBN
  9781071614839, 9781071614846
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04821, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649
[Journal Article] Trends and Limitations in the Assessment of the Contractile Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes From Patients With Dilated Cardiomyopathy2020
- Author(s)
  Ito M, Nomura S, Morita H, Komuro I.
- Journal Title
  
  Front Cardiovasc Med.
  
  Volume: 7 Pages: 154-154
- DOI
  10.3389/fcvm.2020.00154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19K17515
[Journal Article] Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease2020
- Author(s)
  Matsunaga Hiroshi, ... Ogishima Soichi et al.
- Journal Title
  
  Circulation: Genomic and Precision Medicine
  
  Volume: 13 Issue: 3
- DOI
  10.1161/circgen.119.002670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11545, KAKENHI-PROJECT-19K08547, KAKENHI-PROJECT-19K10655, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-18K08097, KAKENHI-PROJECT-20H03943
[Journal Article] Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease2020
- Author(s)
  2.Koyama S, Ito K, Terao C, Akiyama M, Horikoshi M, Momozawa Y, Matsunaga H, Ieki H, Ozaki K, Onouchi Y, Takahashi A, Nomura S, Morita H, Akazawa H, Kim C, Seo JS, Higasa K, Iwasaki M, Yamaji T, et al.
- Journal Title
  
  Nature Genetics
  
  Volume: 52 Issue: 11 Pages: 1169-1177
- DOI
  10.1038/s41588-020-0705-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10655, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-18K08097, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03943
[Journal Article] Review of Single-Cell RNA Sequencing in the Heart2020
- Author(s)
  Yamada S, Nomura S.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 21 Pages: 8345-8345
- DOI
  10.3390/ijms21218345
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649
[Journal Article] Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure2020
- Author(s)
  Yamaguchi Toshihiro、Sumida Tomokazu S.、Nomura Seitaro、Satoh Masahiro、Higo Tomoaki、Ito Masamichi、Ko Toshiyuki、Fujita Kanna、Sweet Mary E.、Sanbe Atsushi、Yoshimi Kenji、Manabe Ichiro、Sasaoka Toshikuni、Taylor Matthew R. G.、Toko Haruhiro、Takimoto Eiki、Naito Atsuhiko T.、Komuro Issei
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 4364-4364
- DOI
  10.1038/s41467-020-18128-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11662, KAKENHI-PROJECT-19K17587, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-19H03662, KAKENHI-PROJECT-18K15881
[Journal Article] Genetic and Non-Genetic Determinants of Clinical Phenotypes in Cardiomyopathy2019
- Author(s)
  Nomura S.
- Journal Title
  
  J Cardiol.
  
  Volume: 73 Issue: 3 Pages: 187-190
- DOI
  10.1016/j.jjcc.2018.11.001
- NAID
  40021821824
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03649
[Journal Article] Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytes2019
- Author(s)
  Ito Masamichi、Hara Hironori、Takeda Norifumi、Naito Atsuhiko T.、Nomura Seitaro、Kondo Masaki、Hata Yutaka、Uchiyama Masanobu、Morita Hiroyuki、Komuro Issei
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 128 Pages: 90-95
- DOI
  10.1016/j.yjmcc.2019.01.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15987, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-19H03414, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-17H06173
[Journal Article] High-throughput single-molecule RNA imaging analysis reveals heterogeneous responses of cardiomyocytes to hemodynamic overload2019
- Author(s)
  Satoh M、Nomura S、Harada M、Yamaguchi T、Ko T、Sumida T、Toko H、Naito AT.、Takeda N、Tobita T、Fujita T、Ito M、Fujita K、Ishizuka M、Kariya T、Akazawa H、Kobayashi Y、Morita H、Takimoto E、Aburatani H、Komuro I
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 128 Pages: 77-89
- DOI
  10.1016/j.yjmcc.2018.12.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06566, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-18K08097
[Journal Article] Quantification of DNA Damage in Heart Tissue as a Novel Prediction Tool for Therapeutic Prognosis of Patients With Dilated Cardiomyopathy.2019
- Author(s)
  Ko T, Fujita K, Nomura S, Uemura Y, Yamada S, Tobita T, Katoh M, Satoh M, Ito M, Domoto Y, Hosoya Y, Amiya E, Hatano M, Morita H, Fukayama M, Aburatani H, Komuro I.
- Journal Title
  
  JACC Basic Transl Sci.
  
  Volume: 4 Issue: 6 Pages: 670-680
- DOI
  10.1016/j.jacbts.2019.05.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-17H04061, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-17K08717
[Journal Article] Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure.2018
- Author(s)
  Nomura S, Satoh M, Fujita T, Higo T, Sumida T, Ko T, Yamaguchi T, Tobita T, Naito AT, Ito M, Fujita K, Harada M, Toko H, Kobayashi Y, Ito K, Takimoto E, Akazawa H, Morita H, Aburatani H, Komuro I.
- Journal Title
  
  Nat Commun.
  
  Volume: 9 Issue: 1 Pages: 4435-4435
- DOI
  10.1038/s41467-018-06639-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-16H04726, KAKENHI-PROJECT-17H04061, KAKENHI-PROJECT-17H06566, KAKENHI-PROJECT-18K08097
[Journal Article] Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling2018
- Author(s)
  Tobita T, Nomura S, Fujita T, Morita H, Asano Y, Onoue K, Ito M, Imai Y, Suzuki A, Ko T, Satoh M, Fujita K, Naito AT, Furutani Y, Toko H, Harada M, Amiya E, Hatano M, Takimoto E, Shiga T, Nakanishi T, Sakata Y, Ono M, Saito Y, Takashima S, Hagiwara N, Aburatani H, Komuro I.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 20114-20119
- DOI
  10.1038/s41598-018-20114-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09129, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-17H04061, KAKENHI-PROJECT-17J00085, KAKENHI-PROJECT-17J05937, KAKENHI-PROJECT-15K21388, KAKENHI-PROJECT-17H06566, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-15K09139
[Journal Article] DNA single-strand break-induced DNA damage response causes heart failure.2017
- Author(s)
  Higo T, Naito AT, Sumida T, Shibamoto M, Okada K, Nomura S, Nakagawa A, Yamaguchi T, Sakai T, Hashimoto A, Kuramoto Y, Ito M, Hikoso S, Akazawa H, Lee JK, Shiojima I, McKinnon PJ, Sakata Y, Komuro I.
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 15104-15104
- DOI
  10.1038/ncomms15104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01560
[Journal Article] Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1.2017
- Author(s)
  Nakamura S, Koyama T, Izawa N, Nomura S, Fujita T, Omata Y, Minami T, Matsumoto M, Nakamura M, Fujita-Jimbo E, Momoi T, Miyamoto T, Aburatani H, Tanaka S.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 4 Pages: e0175632-e0175632
- DOI
  10.1371/journal.pone.0175632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19371, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26253075, KAKENHI-PROJECT-15H04963, KAKENHI-PROJECT-17H03580
[Journal Article] Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure.2017
- Author(s)
  Kamo T, Akazawa H, Suda W, Saga-Kamo A, Shimizu Y, Yagi H, Liu Q, Nomura S, Naito AT, Takeda N, Harada M, Toko H, Kumagai H, Ikeda Y, Takimoto E, Suzuki JI, Honda K, Morita H, Hattori M, Komuro I.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 3 Pages: 0174099-0174099
- DOI
  10.1371/journal.pone.0174099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-26460333, KAKENHI-PROJECT-26461124, KAKENHI-PROJECT-15K19371, KAKENHI-PROJECT-15K09132, KAKENHI-PROJECT-17K08585, KAKENHI-PROJECT-17K19673, KAKENHI-PROJECT-17K15989, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-16K15199, KAKENHI-PROJECT-17H01560
[Journal Article] Identification of MYLK3 mutations in familial dilated cardiomyopathy2017
- Author(s)
  Tobita Takashige、Nomura Seitaro、Morita Hiroyuki、Ko Toshiyuki、Fujita Takanori、Toko Haruhiro、Uto Kenta、Hagiwara Nobuhisa、Aburatani Hiroyuki、Komuro Issei
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 17495-17495
- DOI
  10.1038/s41598-017-17769-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-17H04061, KAKENHI-PROJECT-17J00085, KAKENHI-PROJECT-17J05937, KAKENHI-PROJECT-16K15199, KAKENHI-PROJECT-17H01560
[Journal Article] CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data2017
- Author(s)
  duVerle DA, Yotsukura S, Nomura S, Aburatani H, Tsuda K
- Journal Title
  
  BMC Bioinformatics
  
  Volume: 17 Issue: 1 Pages: 363-363
- DOI
  10.1186/s12859-016-1175-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15K19371
[Journal Article] Activation of endothelial β-catenin signaling induces heart failure.2016
- Author(s)
  Nakagawa A, Naito AT, Sumida T, Nomura S, Shibamoto M, Higo T, Okada K, Sakai T, Hashimoto A, Kuramoto Y, Oka T, Lee JK, Harada M, Ueda K, Shiojima I, Limbourg FP, Adams RH, Noda T, Sakata Y, Akazawa H, Komuro I.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 25009-25009
- DOI
  10.1038/srep25009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293188, KAKENHI-PROJECT-15K19371
[Journal Article] Hypoxia-Inducible Factor-1α Activates the Transforming Growth Factor-β/SMAD3 Pathway in Kidney Tubular Epithelial Cells.2016
- Author(s)
  Kushida N, Nomura S, Mimura I, Fujita T, Yamamoto S, Nangaku M, Aburatani H.
- Journal Title
  
  American Journal of Nephrology
  
  Volume: 44 Pages: 276-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19371
[Journal Article] Wnt/β-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box O.2015
- Author(s)
  Okada K, Naito AT, Higo T, Nakagawa A, Shibamoto M, Sakai T, Hashimoto A, Kuramoto Y, Sumida T, Nomura S, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Morimoto S, Sakata Y, Shiojima I, Komuro I.
- Journal Title
  
  Circ Heart Fail.
  
  Volume: 8 Issue: 4 Pages: 799-808
- DOI
  10.1161/circheartfailure.114.001958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19371, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-26670395
[Journal Article] 心不全における心筋細胞の1細胞heterogeneityとその意義2015
- Author(s)
  野村征太郎、佐藤真洋、藤田隆教、山口敏弘、住田智一、内藤篤彦、東口治弘、油谷浩幸、小室一成
- Journal Title
  
  日本内分泌学会雑誌
  
  Volume: 91 Pages: 636-636
- Data Source
  KAKENHI-PROJECT-26253049
[Journal Article] Quantitative measurement of GPCR endocytosis via pulse-chase covalent labeling2015
- Author(s)
  Kumagai H, Ikeda Y, Motozawa Y, Fujishiro M, Okamura T, Fujio K, Okazaki H, Nomura S, Takeda N, Harada M, Toko H, Takimoto E, Akazawa H, Morita H, Suzuki J, Yamazaki T, Yamamoto K, Komuro I, Yanagisawa M
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 5 Pages: e0129394-e0129394
- DOI
  10.1371/journal.pone.0129394
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460333, KAKENHI-PROJECT-26461124, KAKENHI-PROJECT-15K19371, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-15K15047, KAKENHI-PROJECT-26670395
[Journal Article] Monitoring beta-arrestin recruitment via beta-lactamase enzyme fragment complementation: purification of peptide E as a low-affinity ligand for mammalian bombesin receptors2015
- Author(s)
  Ikeda Y*, Kumagai H*, Okazaki H, Fujishiro M, Motozawa Y, Nomura S, Takeda N, Toko H, Takimoto E, Akazawa H, Morita H, Suzuki J, Yamazaki T, Komuro I, Yanagisawa M (co-first author)
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0127445-e0127445
- DOI
  10.1371/journal.pone.0127445
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460333, KAKENHI-PROJECT-26461124, KAKENHI-PROJECT-15K19371, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-15K15047, KAKENHI-PROJECT-26670395
[Journal Article] Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling.2015
- Author(s)
  Sumida T, Naito AT, Nomura S, Nakagawa A, Higo T, Hashimoto A, Okada K, Sakai T, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Minamino T, Offermanns S, Noda T, Botto M, Kobayashi Y, Morita H, Manabe I, Nagai T, Shiojima I, Komuro I.
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 6241-6241
- DOI
  10.1038/ncomms7241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390195, KAKENHI-PROJECT-25293180, KAKENHI-PROJECT-25670382, KAKENHI-PLANNED-26115008, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-26670395, KAKENHI-PROJECT-26713028, KAKENHI-PROJECT-26870141, KAKENHI-PROJECT-15K15306
[Patent] Htra3を治療標的とする心筋梗塞、心臓線維化又は心不全の治療又は予防剤2022
- Inventor(s)
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Holder
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22H00471
[Patent] 心筋梗塞・心不全の治療標的としての心保護因子Htra3の同定2021
- Inventor(s)
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-21H04821
[Patent] 心筋梗塞・心不全の治療標的としての心保護因子Htra3の同定2021
- Inventor(s)
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03649
[Patent] 虚血性心疾患のリスク判定方法及びリスク判定システム2020
- Inventor(s)
  伊藤薫・小山智史・鎌谷洋一郎・野村征太郎・小室一成・油谷浩幸
- Industrial Property Rights Holder
  国立研究開発法人理化学研究所・国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03649
[Patent] 虚血性心疾患発症と予後を予測するゲノムリスクスコア2019
- Inventor(s)
  伊藤薫、野村征太郎、赤澤宏、小室一成
- Industrial Property Rights Holder
  伊藤薫、野村征太郎、赤澤宏、小室一成
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03649
[Patent] 心不全患者の心機能回復可能性の評価方法2019
- Inventor(s)
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Holder
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03649
[Patent] 虚血性心疾患発症と予後を予測するゲノムリスクスコア2019
- Inventor(s)
  伊藤薫、野村征太郎、赤澤宏、小室一成
- Industrial Property Rights Holder
  伊藤薫、野村征太郎、赤澤宏、小室一成
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H01560
[Patent] 心不全患者の心機能回復可能性の評価方法2019
- Inventor(s)
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Holder
  野村征太郎、候聡志、油谷浩幸、小室一成
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17H01560
[Patent] DNA損傷応答を指標にした心不全層別化バイオマーカーの開発2018
- Inventor(s)
  野村征太郎・小室一成・候聡志・油谷浩幸
- Industrial Property Rights Holder
  野村征太郎・小室一成・候聡志・油谷浩幸
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17H01560
[Presentation] Fostering the Next Generation of Basic Researchers in the Cardiovascular Field2023
- Author(s)
  野村征太郎
- Organizer
  The 87th Annual Scientific Meeting of the Japanese Circulation Society
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] Spatiotemporal Molecular Mechanisms of Cardiac Remodeling and their applications for therapeutic Development.2023
- Author(s)
  Seitaro Nomura
- Organizer
  The 87th Annual Scientific Meeting of the Japanese Circulation Society
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] オミックス解析による循環器疾患における精密医療の実現と発展2022
- Author(s)
  野村征太郎.
- Organizer
  第52回日本心脈管作動物質学会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] Spatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction.2022
- Author(s)
  野村征太郎
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] ゲノム・オミックス解析による心筋症の精密医療の発展2022
- Author(s)
  野村征太郎
- Organizer
  第26回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] ゲノム・オミックス解析による心不全の精密医療の発展2022
- Author(s)
  野村征太郎
- Organizer
  第26回日本心不全学会学術集会学術賞　受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] 分野融合的アプローチで心筋症を識る.2022
- Author(s)
  野村征太郎
- Organizer
  第26回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] Single-cell analysis to dissect the biology of heart failure.2022
- Author(s)
  Seitaro Nomura
- Organizer
  The 26th Annual Scientific Meeting of the Japanese Heart Failure Society.
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] 心筋症の精密医療の発展に向けて2022
- Author(s)
  野村征太郎
- Organizer
  第8回心筋症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00471
[Presentation] 循環器疾患システム構造の理解を目指した統合的シングルセル解析2021
- Author(s)
  野村征太郎
- Organizer
  第25回日本心血管内分泌代謝学会学術総会若手主宰シンポジウム「心血管内分泌研究の最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Integrated single-cell analysis to understand the system architecture of cardiovascular disease2021
- Author(s)
  野村征太郎
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04821
[Presentation] Single-cell Analysis Dissects the Biology of Heart Failure2021
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 拡張型心筋症の発症機序2021
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Molecular Mechanisms of Heart Failure2021
- Author(s)
  Seitaro Nomura
- Organizer
  Asian Pacific Society of Cardiology Congress (APSC2022)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] ゲノムからみた心筋症の精密医療2021
- Author(s)
  野村征太郎
- Organizer
  第25回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 心筋梗塞の心臓リモデリングを制御する空間的なメカノセンシング機構2021
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 心不全患者におけるDNA傷害指標の病期評価能を検証する他施設前向き観察研究2021
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 心不全における心筋細胞の分子生物学的考察と臨床応用（心不全のシステム循環器学）2021
- Author(s)
  野村征太郎
- Organizer
  第69回日本心臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Multi-omics Analysis Dissects the Biology of Heart Failure2021
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 統合的シングルセル解析による循環器疾患システム構造の理解と精密医療の発展2021
- Author(s)
  野村征太郎
- Organizer
  第263回日本循環器学会関東甲信越地方会教育セッションⅠ 循環器病克服のための基礎研究のすすめ
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Spatial transcriptomics of cardiovascular diseases2021
- Author(s)
  Seitaro Nomura
- Organizer
  2021 Asia Pacific Spatial Biology Summit
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] ゲノムからみた心筋症の精密医療2021
- Author(s)
  野村征太郎
- Organizer
  第3回老年不整脈研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04821
[Presentation] Multiomics analysis to develop precision medicine in heart failure2021
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Integrated single-cell analysis to understand the system architecture of cardiovascular disease2021
- Author(s)
  Seitaro Nomura
- Organizer
  第44回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 精密医療の実現を目指す次世代型心臓病学2021
- Author(s)
  野村征太郎
- Organizer
  Premium Hypertension Conference
- Invited
- Data Source
  KAKENHI-PROJECT-21H04821
[Presentation] DNA damage leading to heart failure2021
- Author(s)
  Seitaro Nomura
- Organizer
  European Society of Cardiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 環器疾患システム構造の理解を目指した統合的シングルセル解析2021
- Author(s)
  野村征太郎
- Organizer
  第25回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04821
[Presentation] SGLT2阻害薬を中心とした糖尿病・心不全・慢性腎臓病の新たな治療戦略2021
- Author(s)
  野村征太郎
- Organizer
  東村山市医師会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04821
[Presentation] Disease Modeling of Dilated Cardiomyopathy -Application of iPSC and Single-cell Omics Technology2020
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 分子生物学と未来の心不全診療2020
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会関東甲信越地方会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Omics Studies of Dilated Cardiomyopathy -拡張型心筋症のオミックス解析-2020
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] AIによるprecision medicine2020
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 心不全ゲノム診療近未来予想図2020
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] ゲノム分子病理解析による心筋症の病態解明と精密医療2020
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会関東甲信越地方会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Elucidation of mechanism involved in the development and progression of heart failure using single-cell RNA-Seq2020
- Author(s)
  野村征太郎
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 循環器疾患のシングルセルオミクス解析2019
- Author(s)
  野村征太郎
- Organizer
  日本学術会議公開シンポジウム「ゲノムビックデータ解析の新潮流」
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 心臓疾患における細胞・分子挙動の網羅的理解2019
- Author(s)
  野村征太郎
- Organizer
  第23回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Heart Cell Atlas for understanding the pathophysiology of the Heart and for the development of precision cardiovascular medicine2019
- Author(s)
  野村征太郎
- Organizer
  第3回日本循環器学会基礎研究フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Genetic architecture of cardiomyopathy2019
- Author(s)
  Seitaro Nomura
- Organizer
  European Society of Cardiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] シングルセル解析による循環器疾患の病態解明と臨床応用2019
- Author(s)
  野村征太郎
- Organizer
  シングルセル研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] 永井良三賞受賞講演「シングルセルシステム循環器学による循環器疾患システム構造の全貌解明」2019
- Author(s)
  野村征太郎
- Organizer
  第23回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Systems biology for the integrative understanding of cardiac system2019
- Author(s)
  野村征太郎
- Organizer
  第23回日本心血管内分泌代謝学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Multi-omics dissection of heart failure for cardiovascular precision medicine2019
- Author(s)
  Seitaro Nomura
- Organizer
  Cell Symposia Gene regulation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] マルチオミックス連関による心筋症における精密医療の実現2019
- Author(s)
  野村征太郎
- Organizer
  第23回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Multi-omics dissection of heart failure for the development of precision cardiovascular medicine2019
- Author(s)
  Seitaro Nomura
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] ゲノム分子病理解析による心筋症における精密医療の実現2019
- Author(s)
  野村征太郎
- Organizer
  第23回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure2019
- Author(s)
  Seitaro Nomura
- Organizer
  Cell Symposia: Single Cell meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] ntegrative single-cell analysis to dissect heart failure biology2019
- Author(s)
  Seitaro Nomura
- Organizer
  Cold Spring Harbor Laboratory meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Multi-omics dissection of heart failure for precision cardiovascular medicine2019
- Author(s)
  Seitaro Nomura
- Organizer
  Annual Meeting of Taiwan Society of Cardiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Multi-omics dissection of heart failure for cardiovascular precision medicine2019
- Author(s)
  野村征太郎
- Organizer
  第23回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03649
[Presentation] Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure2018
- Author(s)
  Seitaro Nomura
- Organizer
  Scientific Sessions of the American Heart Association 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01560
[Presentation] Comprehensive targeted sequencing of cardiomyopathy and its relation to phenotype2018
- Author(s)
  Seitaro Nomura
- Organizer
  European Society of Cardiology 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01560
[Presentation] Genetics of Cardiomyopathy2017
- Author(s)
  野村征太郎
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-26253049
[Presentation] Genetics of Cardiomyopathy2017
- Author(s)
  野村征太郎
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2017-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K19371
[Presentation] 心筋症のハイスルーブットな遺伝子解析技術の構築とその応用2016
- Author(s)
  野村征太郎、飛田尚重、藤田隆教、油谷浩幸、小室一成
- Organizer
  第20回日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-26253049
[Presentation] システム生物学的アプローチによる心不全１細胞モデリング2016
- Author(s)
  野村征太郎、佐藤真洋、候聡志、藤田隆教、油谷浩幸、小室一成
- Organizer
  第20回日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-26253049
[Presentation] 心不全における心筋細胞の１細胞heterogeneityとその意義2015
- Author(s)
  野村征太郎
- Organizer
  第19回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-15K19371
[Presentation] 心不全における心筋細胞の1細胞heterogeneityとその意義2015
- Author(s)
  野村征太郎、佐藤真洋、藤田隆教、山口敏弘、住田智一、内藤篤彦、東口治弘、油谷浩幸、小室一成
- Organizer
  第19回　日本心血管内分泌代謝学会学術総会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26253049
[Presentation] Epigenomic switch by Wnt/b-catenin signaling directs cardiomyocyte differentiation
- Author(s)
  Seitaro Nomura, Takanori Fujita, Atsuhiko T. Naito, Hiroyuki Aburatani, and Issei Komuro
- Organizer
  Keystone Symposia 2015 Heart Disease and Regeneration
- Place of Presentation
  Copper Mountain, Colorado
- Year and Date
  2015-03-01 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-26253049
[Presentation] Epigenomic switch by Wnt/b-catenin signaling directs cardiomyocyte differentiation
- Author(s)
  Seitaro Nomura, Takanori Fujita, Atsuhiko T. Naito, Hiroyuki Aburatani, and Issei Komuro
- Organizer
  American Heart Association Scientific Sessions 2014
- Place of Presentation
  Chicago
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26253049
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NOMURA SEITARO 野村 征太郎

Nomura Seitaro 野村 征太郎

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Integrative understanding of cardiac system architecture and its regulationPrincipal Investigator

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Single-cell omics analysis to develop the therapy for heart failure via cardiomyocyte reprogrammingPrincipal Investigator

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Cardiomyocyte herogeneity in heart failurePrincipal Investigator

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NOMURA SEITARO 野村征太郎

Nomura Seitaro 野村征太郎

[Book] 循環器内科第86巻第6号「心筋症の遺伝子治療」2019

[Book] 実験医学増刊 Vol.37 No.20 シングルセルゲノミクス組織の機能、病態が1細胞レベルで見えてきた！「心筋シングルセル解析による病態解明から臨床応用」2019