OZAKI HARUKA 尾崎遼

… Alternative Names

Ozaki Haruka 尾崎遼

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Researcher Number	10743346
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 生命機能科学研究センター, チームディレクター 2025: 筑波大学, 医学医療系, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 筑波大学, 医学医療系, 准教授
Review Section/Research Field	Principal Investigator Basic Section 62010:Life, health and medical informatics-related / Transformative Research Areas, Section (III) Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 57040:Regenerative dentistry and dental engineering-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Transformative Research Areas, Section (III) / Biological Sciences / Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator 機械学習 / シングルセル解析 / バイオインフォマティクス / 深層生成モデル / プロモーター配列 / シングルセルRNA-seq / ゲノム配列 / 表現型予測 / 深層学習 / 遺伝子発現 … More Except Principal Investigator … More アレルギー / 発症予測 / 全ゲノム関連解析 / 間葉系幹細胞 / 骨髄間質細胞 / シングルセル解析 / 細胞系譜追跡 / 骨再生 / 骨格幹細胞 / 血管平滑筋細胞 / 平滑筋細胞 / 大動脈解離 / 大動脈瘤 / ECM / 細胞外マトリクス / ナノパーティクル / 内皮細胞 / 血管平滑筋 / 胸部大動脈 / 細胞外マトリックス / 細胞分化 / 単一細胞トランスクリプトーム解析 / 適応回路 / バイオインフォマティクス / 光遺伝学 / シングルセルトランスクリプトーム / 神経回路 / ホヤ / マルチオミクス / システム生物学 / 代謝アダプテーション / ２型糖尿病 / 2型糖尿病 / トランスオミクス / RNA-seq / アレルゲン免疫療法 / single-cell RNA-seq / bulk RNA-seq / TCRシークエンス / RNA-Seq / アレルギー疾患 / シングルセルRNA-Seq / 遺伝子発現 / 免疫療法 / 花粉症 / シングルセル Less

Predicting the functions of glial cells with unknown functions by GLIA-BLASTPrincipal Investigator
- Principal Investigator
  
  尾崎遼
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  University of Tsukuba
Elucidation of the mechanism of thoracic aortic disease based on extracellular matrix and development of novel therapeutic strategy
- Principal Investigator
  
  柳沢裕美
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  University of Tsukuba
ゲノムデータに基づくアレルギー疾患発症予測法の開発
- Principal Investigator
  
  野口恵美子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  University of Tsukuba
敵対的生成ネットワークによる自在な発現特異性を有するプロモータ塩基配列の設計Principal Investigator
- Principal Investigator
  
  尾崎遼
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  University of Tsukuba
Construction mechanism of basic design for adaptive neuronal circuits
- Principal Investigator
  
  堀江健生
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
  University of Tsukuba
多階層シングルセル解析を応用した骨再生機構の解明と新規再生療法の基盤構築
- Principal Investigator
  
  松下祐樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nagasaki University
Development of a method to examine the relationship between phenotype and individual differences in gene expression without the need for gene expression data from a large number of people.Principal Investigator
- Principal Investigator
  
  Ozaki Haruka
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  University of Tsukuba
Identifying the mechanism of allergen immunotherapy using single cell and bulk gene expression information.
- Principal Investigator
  
  Noguchi Emiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Tsukuba
Metabolic adaptation of type 2 diabetes
- Principal Investigator
  
  Kuroda Shinya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Neuronal subtype-specific transcriptomic changes in the cerebral neocortex associated with sleep pressure2024
- Author(s)
  Nakata Shinya、Iwasaki Kanako、Funato Hiromasa、Yanagisawa Masashi、Ozaki Haruka
- Journal Title
  
  Neuroscience Research
  
  Volume: － Pages: 13-25
- DOI
  10.1016/j.neures.2024.03.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17992, KAKENHI-PROJECT-22H04918, KAKENHI-PUBLICLY-23H04149
[Journal Article] Transcription factor-binding k-mer analysis clarifies the cell type dependency of binding specificities and cis-regulatory SNPs in humans2023
- Author(s)
  Tahara Saeko、Tsuchiya Takaho、Matsumoto Hirotaka、Ozaki Haruka
- Journal Title
  
  BMC Genomics
  
  Volume: 24 Issue: 1
- DOI
  10.1186/s12864-023-09692-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17992, KAKENHI-PROJECT-20K19915
[Journal Article] DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle2023
- Author(s)
  Maehara H.、Kokaji T.、Hatano A.、Suzuki Y.、Matsumoto M.、Nakayama K. I.、Egami R.、Tsuchiya T.、Ozaki H.、Morita K.、Shirai M.、Li D.、Terakawa A.、Uematsu S.、Hironaka K.、Ohno S.、Kubota H.、Araki H.、Miura F.、Ito T.、Kuroda S.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 19118-19118
- DOI
  10.1038/s41598-023-46393-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17992, KAKENHI-PROJECT-20K19915, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-21H04759, KAKENHI-PROJECT-23K23870
[Journal Article] CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells2022
- Author(s)
  Tsuchiya Takaho、Hori Hiroki、Ozaki Haruka
- Journal Title
  
  Bioinformatics
  
  Volume: 38 Issue: 21 Pages: 4868-4877
- DOI
  10.1093/bioinformatics/btac599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19915, KAKENHI-PROJECT-19K20394
[Journal Article] In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states.2022
- Author(s)
  Kokaji T, Eto M, Hatano A, Yugi K, Morita K, Ohno S, Fujii M, Hironaka KI, Ito Y, Egami R, Uematsu S, Terakawa A, Pan Y, Maehara H, Li D, Bai Y, Tsuchiya T, Ozaki H, Inoue H, Kubota H, Suzuki Y, Hirayama A, Soga T, Kuroda S.
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 13719-13719
- DOI
  10.1038/s41598-022-17964-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-20K19915, KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-20H03237, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-18H05431, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300
[Journal Article] Integrated analysis of glycan and RNA in single cells2021
- Author(s)
  Minoshima Fumi、Ozaki Haruka、Odaka Haruki、Tateno Hiroaki
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 8 Pages: 102882-102882
- DOI
  10.1016/j.isci.2021.102882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16263, KAKENHI-PROJECT-19K20394
[Journal Article] Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle2021
- Author(s)
  Egami Riku、Kokaji Toshiya、Hatano Atsushi、et al.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 3 Pages: 102217-102217
- DOI
  10.1016/j.isci.2021.102217
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-20K19915, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19J10234, KAKENHI-PROJECT-19J22134, KAKENHI-PROJECT-19K24361, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-18KT0020, KAKENHI-PLANNED-18H05431, KAKENHI-PROJECT-20H03237
[Journal Article] Cell-to-cell interaction analysis of prognostic ligand-receptor pairs in human pancreatic ductal adenocarcinoma2021
- Author(s)
  Suzuki Sayaka R.、Kuno Akihiro、Ozaki Haruka
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 28 Pages: 101126-101126
- DOI
  10.1016/j.bbrep.2021.101126
- Data Source
  KAKENHI-PROJECT-19K20394
[Journal Article] Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity2020
- Author(s)
  Kokaji Toshiya、Hatano Atsushi、Ito Yuki、et al.
- Journal Title
  
  Science Signaling
  
  Volume: 13 Issue: 660 Pages: 1236-1236
- DOI
  10.1126/scisignal.aaz1236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-20K19915, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PUBLICLY-20H04847, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-18H02431, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19K24361, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-18H05431, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-18KT0020, KAKENHI-PROJECT-20H03237
[Journal Article] Stability of RNA sequences derived from the coronavirus genome in human cells2020
- Author(s)
  Wakida Hiroyasu、Kawata Kentaro、Yamaji Yuta、Hattori Emi、Tsuchiya Takaho、Wada Youichiro、Ozaki Haruka、Akimitsu Nobuyoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 527 Issue: 4 Pages: 993-999
- DOI
  10.1016/j.bbrc.2020.05.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16635, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-20K19915, KAKENHI-PROJECT-19K22679, KAKENHI-PROJECT-19K24361
[Presentation] Prediction of the function of functionally unknown glial cells using GLIA-BLAST2023
- Author(s)
  Haruka Ozaki
- Organizer
  グリアデコード第6回領域会議
- Data Source
  KAKENHI-PUBLICLY-23H04149
[Presentation] Glioneuronal mechanisms underlying the regulation of sleep in nucleus accumbens2023
- Author(s)
  Haruto Ijiri, Koustav Roy, Haruka Ozaki, Masashi Yanagisawa, Michael Lazarus
- Organizer
  グリアデコード第6回領域会議
- Data Source
  KAKENHI-PUBLICLY-23H04149
[Presentation] RNA tomographyによる空間遺伝子発現分布推定結果の評価方法の検討2023
- Author(s)
  松澤亮輔, 尾崎遼
- Organizer
  第147回MPS・第77回BIO合同研究発表会
- Data Source
  KAKENHI-PROJECT-22K17992
[Presentation] MOCCS-DB: ヒト転写因子認識配列の多様性データベース2022
- Author(s)
  田原沙絵子, 土屋貴穂, 松澤亮輔, 尾崎遼
- Organizer
  トーゴーの日シンポジウム2022
- Data Source
  KAKENHI-PROJECT-19K20394
[Presentation] MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans2022
- Author(s)
  Saeko Tahara, Takaho Tsuchiya, Hirotaka Matsumoto, Haruka Ozaki
- Organizer
  2022年日本バイオインフォマティクス学会年会・第11回生命医薬情報学連合大会（IIBMP2022）
- Data Source
  KAKENHI-PROJECT-19K20394
[Presentation] 敵対的生成ネットワークによる自在な発現特異性を有するプロモータ配列の設計2022
- Author(s)
  Yukai Takagi, Haruka Ozaki, Akihiro Kuno, Kotaro Sakamoto
- Organizer
  2022年日本バイオインフォマティクス学会年会・第11回生命医薬情報学連合大会（IIBMP2022）
- Data Source
  KAKENHI-PROJECT-22K17992
[Presentation] Predicting SNPs' effects on transcriptional factor binding and cell-type specificity using a crowd of ChIP-seq data2022
- Author(s)
  田原沙絵子, 土屋貴穂, 松本拡高, 尾崎遼
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-19K20394
[Presentation] NGSデータ解析における生命現象のモデル化と自動化2021
- Author(s)
  尾崎遼
- Organizer
  バイオDXの最前線　- JST戦略的創造研究推進事業 CREST「データ駆動・AI駆動を中心としたデジタルトランスフォーメーションによる生命科学研究の革新[バイオDX]」キックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K20394

1. Noguchi Emiko (40344882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Kuroda Shinya (50273850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 渋谷彰 (80216027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 稲葉有香 (20571970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 土屋貴穂 (70853167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 小林大樹 (20448517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 幡野敦 (30755533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 堀江健生 (10455925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤ゆたか (40314174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 柳沢裕美 (40746301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 荏原充宏 (10452393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 平松祐司 (30302417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 徳永千穂 (30451701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 臼杵豊展 (50514535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 木村健一 (50633153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松下祐樹 (00713827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 住田吉慶 (50456654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松下雅樹 (60721115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 小高陽樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 川田健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 井上啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OZAKI HARUKA 尾崎 遼

Ozaki Haruka 尾崎 遼

Research Projects

Research Products

Co-Researchers

Predicting the functions of glial cells with unknown functions by GLIA-BLASTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of thoracic aortic disease based on extracellular matrix and development of novel therapeutic strategy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノムデータに基づくアレルギー疾患発症予測法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

敵対的生成ネットワークによる自在な発現特異性を有するプロモータ塩基配列の設計Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction mechanism of basic design for adaptive neuronal circuits

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多階層シングルセル解析を応用した骨再生機構の解明と新規再生療法の基盤構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a method to examine the relationship between phenotype and individual differences in gene expression without the need for gene expression data from a large number of people.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identifying the mechanism of allergen immunotherapy using single cell and bulk gene expression information.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Metabolic adaptation of type 2 diabetes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Neuronal subtype-specific transcriptomic changes in the cerebral neocortex associated with sleep pressure2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcription factor-binding k-mer analysis clarifies the cell type dependency of binding specificities and cis-regulatory SNPs in humans2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states.2022

OZAKI HARUKA 尾崎遼

Ozaki Haruka 尾崎遼