Tu Hung-Ya ＴｕＨｕｎｇＹａ

Researcher Number	10780835
Other IDs	https://orcid.org/0000-0002-4868-6262
Affiliation (Current)	2025: 大阪大学, 蛋白質研究所, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 大阪大学, 蛋白質研究所, 助教 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 2019 – 2020: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 2018: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 訪問研究員 2017: 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, 訪問研究員
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / Basic Section 56060:Ophthalmology-related / Ophthalmology Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator bipolar cell / retinal organoid / electrophysiology / amacrine cell / retinal degeneration / transplantation / neuroplasticity / reconstruction / deconstruction / photoreceptor cell … More / synapse / retina / ipRGC / ribbon synapse / organoid transplantation / multielectrode array / horizontal cell / 神経科学 / AII amacrine cell / rod bipolar cell / multi-electrode arrary / retinal transplantation / MEA / amarine cell / ganglion cell / organoid … More Except Principal Investigator オルガノイド / 能動的低代謝 / 低温耐性 / 網膜シート / 組織保存法 / 日内休眠 / 低代謝耐性 / 再生医療 / 組織保存 / 冬眠 / 休眠 Less

網膜神経回路の可塑性および再構築の分子機構の解明Principal Investigator
- Principal Investigator
  
  Tu HungYa
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Osaka University
Optimizing the degenerated retinal circuitry for retinal organoid transplantation driven retinal circuitry reconstructionPrincipal Investigator
- Principal Investigator
  
  Tu Hung-Ya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Osaka University
Development of a novel tissue preservation method via mammalian hypometabolism
- Principal Investigator
  
  Takahashi Masayo
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Ritsumeikan University
  Institute of Physical and Chemical Research
Probing the effect of degenerated retina potentiation on the synaptogenesis after iPSC-derived retinal transplantationPrincipal Investigator
- Principal Investigator
  
  Tu Hung-Ya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy2023
- Author(s)
  Watari K, Yamasaki S, Tu H-Y, et al.
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1
- DOI
  10.1038/s42003-023-04543-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18403
[Journal Article] A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation2022
- Author(s)
  Yamasaki Suguru、Tu Hung-Ya、Matsuyama Take、Horiuchi Matsuri、Hashiguchi Tomoyo、Sho Junki、Kuwahara Atsushi、Kishino Akiyoshi、Kimura Toru、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 1 Pages: 103657-103657
- DOI
  10.1016/j.isci.2021.103657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18403
[Journal Article] Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates2022
- Author(s)
  Uyama H, Tu H-Y, et al.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 17 Issue: 11 Pages: 2392-2408
- DOI
  10.1016/j.stemcr.2022.09.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18403
[Journal Article] Genetically engineered stem cell-derived retinal grafts for improved retinal reconstruction after transplantation2021
- Author(s)
  Matsuyama T, Tu H-Y, Sun J, Hashiguchi T, Akiba R, Sho J, Fujii M, Onishi A, Takahashi M, Mandai M
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 8 Pages: 102866-102866
- DOI
  10.1016/j.isci.2021.102866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09942, KAKENHI-PROJECT-20K18403
[Journal Article] Multielectrode Array Recording of Mouse Retinas Transplanted with Stem Cell-Derived Retinal Sheets2020
- Author(s)
  Hung-Ya Tu, Take Matsuyama
- Journal Title
  
  Retinal Development. Methods in Molecular Biology
  
  Volume: 2092 Pages: 207-220
- DOI
  10.1007/978-1-0716-0175-4_15
- ISBN
  9781071601747, 9781071601754
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994
[Journal Article] Quantitative and Qualitative Evaluation of Photoreceptor Synapses in Developing, Degenerating and Regenerating Retinas2019
- Author(s)
  Akiba Ryutaro、Matsuyama Take、Tu Hung-Ya、Hashiguchi Tomoyo、Sho Junki、Yamamoto Shuichi、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 13
- DOI
  10.3389/fncel.2019.00016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994
[Journal Article] Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration2019
- Author(s)
  Tu Hung-Ya、Watanabe Takehito、Shirai Hiroshi、Yamasaki Suguru、Kinoshita Masaharu、Matsushita Keizo、Hashiguchi Tomoyo、Onoe Hirotaka、Matsuyama Take、Kuwahara Atsushi、Kishino Akiyoshi、Kimura Toru、Eiraku Mototsugu、Suzuma Kiyoshi、Kitaoka Takashi、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  EBioMedicine
  
  Volume: 39 Pages: 562-574
- DOI
  10.1016/j.ebiom.2018.11.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994, KAKENHI-PROJECT-16K06983
[Journal Article] Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation2018
- Author(s)
  Iraha Satoshi、Tu Hung-Ya、Yamasaki Suguru、Kagawa Takahiro、Goto Motohito、Takahashi Riichi、Watanabe Takehito、Sugita Sunao、Yonemura Shigenobu、Sunagawa Genshiro A.、Matsuyama Take、Fujii Momo、Kuwahara Atsushi、Kishino Akiyoshi、Koide Naoshi、Eiraku Mototsugu、Tanihara Hidenobu、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Issue: 3 Pages: 1059-1074
- DOI
  10.1016/j.stemcr.2018.01.032
- NAID
  120007037461
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994, KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-17H04351, KAKENHI-PROJECT-15K10913, KAKENHI-PROJECT-18H02959, KAKENHI-PROJECT-16K21633
[Journal Article] Culture Systems of Dissociated Mouse and Human Pluripotent Stem Cell?Derived Retinal Ganglion Cells Purified by Two-Step Immunopanning2018
- Author(s)
  Kobayashi Wataru、Onishi Akishi、Tu Hung-Ya、Takihara Yuji、Matsumura Michiru、Tsujimoto Kazuko、Inatani Masaru、Nakazawa Toru、Takahashi Masayo
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 59 Issue: 2 Pages: 776-776
- DOI
  10.1167/iovs.17-22406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16994, KAKENHI-PROJECT-16H05486
[Journal Article] Genetically engineered iPSC-retina for improved retinal reconstruction after transplantation2018
- Author(s)
  Tu Hung-Ya、Matsuyama Takesi、Sun Jianan、Hashiguchi Tomoyo、Sho Junki、Sunagawa Genshiro A.、Fujii Momo、Onishi Akishi、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  Investigative Ophthalmology & Visual Science
  
  Volume: 59 Pages: 1987-1987
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994
[Presentation] Effect of ambient light and BDNF on photoreceptor synaptogenesis after mouse ESC/iPSC-derived retinal organoid transplantation2019
- Author(s)
  Ryutaro Akiba; Take Matsuyama; Hung-Ya Tu; Tomoyo Hashiguchi; Sho Junki; Shuichi Yamamoto; Yasuhiko Tabata; Masayo Takahashi; Michiko Mandai
- Organizer
  ARVO Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994
[Presentation] Functional examination of genetically engineered human ESC-retinas transplanted in an immunodeficient rat model with retinal degeneration2019
- Author(s)
  Tu Hung-Ya, Yamasaki Suguru, Matsuyama Take, Kuwahara Atsushi, Kishino Akiyoshi, Kimura Toru, Takahashi Masayo, Mandai Michiko
- Organizer
  ARVO Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994
[Presentation] Functional examination of genetically engineered human ESC-retinas transplanted in an immunodeficient rat model with retinal degeneration2019
- Author(s)
  Hung-Ya Tu; Suguru Yamasaki; atsushi kuwahara; Akiyoshi Kishino; Toru Kimura; Masayo Takahashi; Michiko Mandai
- Organizer
  ARVO Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994
[Presentation] Functional integration of human ESC-derived retinal sheets after transplantation into immune-deficient retinal degeneration mice2018
- Author(s)
  Tu Hung-Ya, Iraha Satoshi, Yamasaki Suguru, Matsuyama Take, Sunagawa Genshiro A., Watanabe Takehito, Hashiguchi Tomoyo, Sho Junki, Takahashi Masayo, Mandai Michiko
- Organizer
  TERMIS World Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994
[Presentation] Genetically engineered iPSC-retina for improved retinal reconstruction after transplantation2018
- Author(s)
  Hung-Ya Tu, Take Matsuyama, Jianan Sun, Tomoyo Hashiguchi, Junki Sho, Genshiro A. Sunagawa, Momo Fujii, Akishi Onishi, Masayo Takahashi, Michiko Mandai
- Organizer
  ARVO Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994

1. Takahashi Masayo (80252443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 砂川玄志郎 (70710250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 万代道子 (80263086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Tu Hung-Ya Ｔｕ ＨｕｎｇＹａ

Research Projects

Research Products

Co-Researchers

網膜神経回路の可塑性および再構築の分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optimizing the degenerated retinal circuitry for retinal organoid transplantation driven retinal circuitry reconstructionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel tissue preservation method via mammalian hypometabolism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Probing the effect of degenerated retina potentiation on the synaptogenesis after iPSC-derived retinal transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetically engineered stem cell-derived retinal grafts for improved retinal reconstruction after transplantation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multielectrode Array Recording of Mouse Retinas Transplanted with Stem Cell-Derived Retinal Sheets2020

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Quantitative and Qualitative Evaluation of Photoreceptor Synapses in Developing, Degenerating and Regenerating Retinas2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Culture Systems of Dissociated Mouse and Human Pluripotent Stem Cell?Derived Retinal Ganglion Cells Purified by Two-Step Immunopanning2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetically engineered iPSC-retina for improved retinal reconstruction after transplantation2018

Author(s)

Journal Title

Data Source

[Presentation] Effect of ambient light and BDNF on photoreceptor synaptogenesis after mouse ESC/iPSC-derived retinal organoid transplantation2019

Tu Hung-Ya ＴｕＨｕｎｇＹａ