isobe ken-ichi 磯部健一

… Alternative Names

ISOBE Ken-ichi 磯部健一

磯部健一イソベケンイチ

ISOBE K 磯部健一

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Researcher Number	20151441
Other IDs
Affiliation (Current)	2025: 修文大学, 医療科学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 修文大学, 医療科学部, 教授 2015 – 2019: 名古屋女子大学, 家政学部, 教授 2011 – 2014: 名古屋大学, 医学(系)研究科(研究院), 教授 2013: 名古屋大学, 医学系研究科, 教授 2010: 名古屋大学, 大学院・医学研究科, 教授 … More 2007 – 2009: Nagoya University, 大学院・医学系研究科, 教授 2004: 名古屋大学, 大学院・医学系研究科, 教授 2003: 国立長寿医療センター, (研究所)・老化機構研究部, 部長 2002: 国立療養所中部病院, 長寿医療研究センター・老化機構研究部, 部長 2001: 国立療養所中部病院(長寿医療研究センター), 老化機構研究部, 部長 1996: The National Sanatorium Chubu Hospital, National Institute for Longevity Science, 長寿医療研究センター, 老化機構研究部長 1993 – 1996: 名古屋大学, 医学部, 助教授 1994 – 1995: 名古屋大学, 医学部・免疫学講座, 助教授 1988 – 1991: 名古屋大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / General surgery / Laboratory animal science / Digestive surgery / Kidney internal medicine / Neurochemistry/Neuropharmacology / Experimental pathology / Metabolomics
Keywords	Principal Investigator GADD34 / ストレス / 老化 / ERストレス / 防御システム / 生活習慣病 / メタボリックシンドローム / インスリンシグナル / 脂肪肝 / 再生 … More / p53 / 蛋白合成阻害 / 転写 / 細胞膜 / 糖尿病 / 脂質二重膜 / インスリンシグナリング / ストレス応答 / 糖質 / 鶏卵 / 免疫 / ２型糖尿病 / 潰瘍性大腸炎 / 自然免疫系細胞 / iPS / 免疫疾患 / iPS細胞 / 組織傷害 / 疾患 / 活性酸素 / 自己免疫 / 生体応答 / マクロファージ / eIF2α / ER / ミクログリア細胞 / A-beta / 酸化ストレス / WAF1 / p21 / 細胞増殖停止 / p53リン酸化 / 細胞周期停止 / Zfp148 / シスエレメント / 生体防御 / ノックアウトマウス / BFCOL-1 / アルキル化剤 / 胸腺腫 / 遺伝子移入 / CEA抗原 / 細胞接着 / 癌転移 / トランスジェニックマウス … More Except Principal Investigator トランスジェニックマウス / メラノ-マ / シグナル伝達系 / インスリンシグナル伝達系 / 老化 / GADD34 / AIDS / 遺伝子治療 / GDNF / L-NAME / Complement regulatory factor / 遺伝子操作 / 補体制御因子 / 異種移植 / 腫瘍免疫 / 代謝系 / 細胞老化 / MEF細胞 / 免疫 / 栄養 / 炎症 / インスリンレセプターシグナル伝達系 / NASH / JNK / インスリン抵抗性 / 脂質代謝 / 糖質代謝 / 肝臓 / Antisense RNA / Transgenic mouse / Gene therapy / Human immunodeficiency virus / CD4 gene / Model animal / T細胞 / アンチセンスRNA / CD4遺伝子 / モデル動物 / gene therapy / gastrointestinal cancer / adenovirus / 細胞性免疫 / 消化器癌 / アデノウイルス / basic fibroblast growth factor / mesangial cells / apoptosis / heparansulfate / ヘパリン / 塩基性線維芽細胞成長因子 / メサンギウム細胞 / アポトーシスの制御 / ヘパラン硫酸 / Gliosis / iNOS / Microglia / Striatum / MPTP / ドーパミン神経 / NO合成酵素 / グリア細胞 / グリオーシス / 誘導型NO合成酵素 / ミクログリア / 線条体 / Gene engineering / Xenoantigen / Transgenic pig / Xenotransplantaion / トランスジェニック動物 / 補体制御因子遺伝子 / トランスジェニックブタ / 異種抗原 / Hyperacute rejection / Xenoantibody production / Gene Engineering / Xenotransplantation / marzinal zone / gene engineering / 超急性拒絶反応 / 抗体産生 / Tyrosine phosphorylation / Melanocytic tumor / Transgenic mice / Ret oncogene / チロシンリン酸化蛋白 / チロシン燐酸化蛋白 / 色素細胞腫瘍 / ret癌遺伝子 / iPS細胞 / 再生医療 / 糖尿病性神経障害 / 神経堤細胞 / 人工多能性幹細胞 / 細胞移植 / 糖尿病性多発神経障害 / 免疫遺伝子治療 / TNFレセプター / がん遺伝子ret / 発がん制御 / 前がん / プレ-Bリンホマ / メラノ-シス / retがん遺伝子 / がん遺伝子 / 免疫反応 / がん発生 Less

GADD34が細胞老化、個体老化を制御するメカニズムの解明
- Principal Investigator
  
  西尾尚美
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Saitama University
Analysis of the Control Mechanism of Age-related Diseases by GADD34
- Principal Investigator
  
  Nishio Naomi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Saitama University
Stress responsive GADD34 and metabolic syndromePrincipal Investigator
- Principal Investigator
  
  isobe ken-ichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagoya Women's University
Age-related diseases analyzed by ER stresses and immune functions using murine models including iPSCsPrincipal Investigator
- Principal Investigator
  
  isobe ken-ichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagoya Women's University
  Nagoya University
Effects of transplantation of neural crest cells derived from iPS cells on diabetic polyneuropathy in mice
- Principal Investigator
  
  NAKAMURA Jiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Aichi Medical University
Analysis of tissue failure and treatment by iPSCsPrincipal Investigator
- Principal Investigator
  
  ISOBE Ken-ichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagoya University
Host responses to stress and progression to diseasePrincipal Investigator
- Principal Investigator
  
  ISOBE Ken-ichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Nagoya University
ストレス防御系の破綻としての癌発生に関する研究Principal Investigator
- Principal Investigator
  
  磯部健一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
ストレス防御系の破綻としての癌発生に関する研究Principal Investigator
- Principal Investigator
  
  磯部健一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences,NCGG
ERストレス応答におけるGADD34蛋白の役割Principal Investigator
- Principal Investigator
  
  磯部健一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
  National Institute for Longevity Sciences,NCGG
ストレス防御系の破綻としての癌発生に関する研究Principal Investigator
- Principal Investigator
  
  磯部健一
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences,NCGG
ストレス防御系の破綻としての癌発生に関する研究Principal Investigator
- Principal Investigator
  
  磯部健一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences,NCGG
Basic fibroblast growth factor (bFGF) requires heparan sulfate (HS) that contains bFGF-binding domains for regulating gllomerular cell apoptosis (AP)
- Principal Investigator
  
  SHINZATO Toru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nagoya University
Gene therapy of gastrointestinal cancer using adenoviral vector
- Principal Investigator
  
  AKIYAMA Seiji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya University
Establishment of Transgenic Pig for Organ Xenotransplantation
- Principal Investigator
  
  TAKAGI Hiroshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Role of Glial Inducible Nitric Oxide Synthase (iNOS) in Focal Brain Injury
- Principal Investigator
  
  KIUCHI Kazutoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  RIKEN (The Institute of Physical and Chemical Research)
トランスジェニックマウス発がん個体において有効な免疫遺伝子治療法開発のための基礎的研究
- Principal Investigator
  
  中島泉
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
Study of Xenotransplatation Using Gene Engineering Technique
- Principal Investigator
  
  TAKAGI Hiroshi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
CEAトランスジェニックマウスにおけるがん細胞の接着と転移に関する研究Principal Investigator
- Principal Investigator
  
  磯部健一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
がん遺伝子トランスジェニックマウス前がん段階の免疫調節による発がんの制御
- Principal Investigator
  
  中島泉
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
メラノ-マ好発系トランスジェニックマウスにおけるがん発生初期段階の免疫反応の解析
- Principal Investigator
  
  NAKASHIMA Izumi
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
Melanovytic tumor development in transgenic mice carrying the ret oncogene
- Principal Investigator
  
  TAKAHASHI Masahide
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University
Human CD4 gene transgenic mouse as an AIDS model animal.
- Principal Investigator
  
  KATSURA Yoshimoto
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Laboratory animal science
- Research Institution
  KYOTO UNIVERSITY

[Book] 管理栄養士のための臨床医科学32017
- Author(s)
  磯部　健一
- Total Pages
  84
- Publisher
  三恵社
- ISBN
  9784864877350
- Data Source
  KAKENHI-PROJECT-16H05280
[Book] 管理栄養士のための臨床医科学２2017
- Author(s)
  磯部　健一
- Total Pages
  91
- Publisher
  三恵社
- ISBN
  9784864876681
- Data Source
  KAKENHI-PROJECT-16H05280
[Book] 老化の生物学2014
- Author(s)
  磯部健一
- Total Pages
  351
- Publisher
  化学出版
- Data Source
  KAKENHI-PROJECT-25293166
[Book] Tissue damage and repair caused by immune system and personalized therapy of failed organs by stem cells2013
- Author(s)
  Isobe K, Nishio N, Thanasegaran S, Cheng Z, Ito S
- Total Pages
  363
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-22390144
[Book] Mouse Development From Oocyte to Stem Cells2012
- Author(s)
  Ken-ichi Isobe, Zhao Cheng, Sachiko Ito, Naomi Nishio
- Total Pages
  438
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22390144
[Book] STEM CELL THERAPY2011
- Author(s)
  Isobe K.
- Total Pages
  102
- Publisher
  TRANSWORLD RESEARCH NETWORK
- Data Source
  KAKENHI-PROJECT-22390144
[Book] 免疫系の加齢変化(新老年学)2010
- Author(s)
  磯部健一
- Data Source
  KAKENHI-PROJECT-19390191
[Book] Specific serum-free conditions can differentiate mouse embryonic stem cells into osteochondrogenic and myogenic progenitors
- Author(s)
  H. Sakurai, Y, Inami, N. Nishio, S. Ito, T. Yoshikai, H. Suzukiand K. Isobe
- Total Pages
  2010
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Hen egg only diets support healthy aging in adult mice2023
- Author(s)
  Naomi Nishio, Ken-ich Isobe
- Journal Title
  
  Journal of Animal Physiology and Animal Nutrition
  
  Volume: - Issue: 4 Pages: 1110-1124
- DOI
  10.1111/jpn.13805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11687
[Journal Article] Hen-egg suppresses fatty liver induced by sugar, glucose or fructose.2021
- Author(s)
  Ken-ichi Isobe, Rena Suzuki, Kana Kato, Miki Kawai, Ami Kuzuya, Aoi Kanjya, Chiaki Suitou, Yui Nakano, Manae Nagasaki, Aki Hatanaka, Asuka Konno and Naomi Nishio
- Journal Title
  
  Journal of Lipid Nutrition
  
  Volume: 30 Pages: 1-17
- NAID
  130008049519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11687
[Journal Article] Are Mice Born Normally With an Egg-only Diet?2020
- Author(s)
  Ken-ichi Isobe, Naomi Nishio
- Journal Title
  
  Biomedical Research and Reviews
  
  Volume: 3.4 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11687
[Journal Article] 加齢に伴う免疫機能の変化2019
- Author(s)
  磯部健一
- Journal Title
  
  医学のあゆみ
  
  Volume: 269 Pages: 238-243
- Data Source
  KAKENHI-PROJECT-16H05280
[Journal Article] 免疫老化と腸管免疫2019
- Author(s)
  磯部健一
- Journal Title
  
  消化器、肝臓内科
  
  Volume: 6(5) Pages: 386-392
- Data Source
  KAKENHI-PROJECT-16H05280
[Journal Article] Do mice grow normally with an egg-only diet?2018
- Author(s)
  Nishio N, Isobe K, Nishi H, Atsumi E, Asai H, Furusawa C
- Journal Title
  
  Peer J. Preprint
  
  Volume: -
- Open Access
- Data Source
  KAKENHI-PROJECT-16H05280
[Journal Article] Functional validation of ATF4 and GADD34 in Neuro2a cells by CRISPR/Cas9-mediated genome editing.2018
- Author(s)
  Oh-hashi K, Sugiura N, Amaya F, Isobe KI, Hirata Y.
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 440 Issue: 1-2 Pages: 65-75
- DOI
  10.1007/s11010-017-3156-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19901, KAKENHI-PROJECT-15H04969, KAKENHI-PROJECT-26670692, KAKENHI-PROJECT-16H05280
[Journal Article] 加齢関連疾患と免疫2018
- Author(s)
  磯部健一
- Journal Title
  
  臨床免疫、アレルギー科
  
  Volume: 70 (5) Pages: 490-496
- Data Source
  KAKENHI-PROJECT-16H05280
[Journal Article] Female GADD34 mice develop age-related inflammation and hepatocellular carcinoma2017
- Author(s)
  Nishio Naomi、Hasegawa Tadao、Tatsuno Ichiro、Isaka Masanori、Isobe Ken-ichi
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 17 Issue: 12 Pages: 2593-2601
- DOI
  10.1111/ggi.13080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-16K01827, KAKENHI-PROJECT-26461512, KAKENHI-PROJECT-16H05280
[Journal Article] 腸内細菌と老化2017
- Author(s)
  磯部健一、西尾尚美
- Journal Title
  
  細胞
  
  Volume: 49 Pages: 17-20
- Data Source
  KAKENHI-PROJECT-16H05280
[Journal Article] Immunological aspects of age-related diseases.2017
- Author(s)
  Isobe KI, Nishio N, Hasegawa T.
- Journal Title
  
  World Journal of Biological Chemistry. Review
  
  Volume: 8(2) Issue: 2 Pages: 129-137
- DOI
  10.4331/wjbc.v8.i2.129
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01827, KAKENHI-PROJECT-16H05280
[Journal Article] Vancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils.2016
- Author(s)
  Tanaka Y, Ito S, Isobe K.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 23920-23920
- DOI
  10.1038/srep23920
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05280, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-15K01708
[Journal Article] Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice.2016
- Author(s)
  Du Q, Tsuboi N, Shi Y, Ito S, Sugiyama Y, Furuhashi K, Endo N, Kim H, Katsuno T, Akiyama S, Matsuo S, Isobe KI, Maruyama S.
- Journal Title
  
  Am J Pathol.
  
  Volume: 186 Pages: 3176-3188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05280
[Journal Article] Predominant role of msr(D) over mef(A) in macrolide resistance in Streptococcus pyogenes.2016
- Author(s)
  Zhang Y, Tatsuno I, Okada R, Hata N, Matsumoto M, Isaka M, Isobe K, Hasegawa T.
- Journal Title
  
  microbiology
  
  Volume: 162 Issue: 1 Pages: 46-52
- DOI
  10.1099/mic.0.000206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09575, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26461512
[Journal Article] GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation.2016
- Author(s)
  Ito S, Tanaka Y, Oshino R, Okado S, Hori M, Isobe KI.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 7 Issue: 5 Pages: e2219-e2219
- DOI
  10.1038/cddis.2016.116
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05280, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-15K01708
[Journal Article] Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice.2016
- Author(s)
  Du Q, Tsuboi N, Shi Y, Ito S, Sugiyama Y, Furuhashi K, Endo N, Kim H, Katsuno T, Akiyama S, Matsuo S, Isobe KI, Maruyama S.
- Journal Title
  
  Am J Pathol.
  
  Volume: 186 Issue: 12 Pages: 3176-3188
- DOI
  10.1016/j.ajpath.2016.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-15K09256, KAKENHI-PROJECT-16K09611
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).2016
- Author(s)
  Klionsky DJ, ---Isobe K他
- Journal Title
  
  Autophagy
  
  Volume: 12(1) Pages: 1-222
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293166
[Journal Article] GADD34 Facilitates Cell Death Resulting from Proteasome Inhibition.2015
- Author(s)
  Liu L, Ito S, Nishio N, Sun Y, Chen N, Tanaka Y, Isobe K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 35(10) Pages: 5317-5324
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293166
[Journal Article] Analysis of the roles of NrdR and DnaB from Streptococcus pyogenes in response to host defense.2015
- Author(s)
  Zhang Y, Okada R, Isaka M, Tatsuno I, Isobe K, Hasegawa T.
- Journal Title
  
  APMIS
  
  Volume: 123 Issue: 3 Pages: 252-259
- DOI
  10.1111/apm.12340
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590531, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26461512
[Journal Article] Angioblast derived from ES cells construct blood vessels and ameliorate diabetic polyneuropathy in mice.2015
- Author(s)
  Himeno T
- Journal Title
  
  Journal of Diabetes Research
  
  Volume: 2015 Pages: 257230-257230
- DOI
  10.1155/2015/257230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293144, KAKENHI-PROJECT-25293166
[Journal Article] Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice2015
- Author(s)
  Tanaka Y, Ito S, Oshino R, Chen N, Nishio N, Isobe K.
- Journal Title
  
  Br J Cancer.
  
  Volume: 113 Issue: 4 Pages: 669-679
- DOI
  10.1038/bjc.2015.263
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01708, KAKENHI-PROJECT-26870257, KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] ADD34-deficient mice develop obesity, nonalcoholic fatty liver disease, hepatic carcinoma and insulin resistance.2015
- Author(s)
  Naomi Nishio and Ken-ichi Isobe.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 13519-13519
- DOI
  10.1038/srep13519
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870257, KAKENHI-PROJECT-25293166
[Journal Article] Thymic Epithelial Cells Induced from Pluripotent Stem Cells by a Three-Dimensional Spheroid Culture System Regenerates Functional T Cells in Nude Mice.2015
- Author(s)
  41. Okabe Motohito, Sachiko Ito, Naomi Nishio, Yuriko Tanaka and Ken-ichi Isobe
- Journal Title
  
  Cell Reprogramming
  
  Volume: 17(5) Issue: 5 Pages: 368-375
- DOI
  10.1089/cell.2015.0006
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870257, KAKENHI-PROJECT-25293166
[Journal Article] Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model.2015
- Author(s)
  Chen N, Nishio N, Ito S, Tanaka Y, Sun Y, Isobe K.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 64 Issue: 6 Pages: 777-789
- DOI
  10.1007/s00262-015-1690-8
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01708, KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy2015
- Author(s)
  Ito S, Tanaka Y, Oshino R, Aiba K, Thanasegaran S, Nishio N, Isobe K
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 8327-8327
- DOI
  10.1038/srep08327
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257
[Journal Article] iPSCs, aging and age-related diseases.2014
- Author(s)
  Isobe K, Cheng Z, Nishio N, Suganya T, Tanaka Y, Ito S.
- Journal Title
  
  N Biotechnol
  
  Volume: 31 Issue: 5 Pages: 411-421
- DOI
  10.1016/j.nbt.2014.04.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257
[Journal Article] Negative regulation of GADD34 on myofibroblasts during cutaneous wound healing.2014
- Author(s)
  Liu L, Nishio N, Ito S, Tanaka Y, Isobe K.
- Journal Title
  
  Biomed Res Int
  
  Volume: 2014 Pages: 137049-137049
- DOI
  10.1155/2014/137049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257
[Journal Article] Acrolein induced both pulmonary inflammation and the death of lung epithelial cells2014
- Author(s)
  Sun Y, Ito S, Nishio N, Tanaka Y, Chen N, Isobe K.
- Journal Title
  
  Toxicol Lett.
  
  Volume: 229 Pages: 384-392
- DOI
  10.1155/2015/170309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257, KAKENHI-PROJECT-15K01708, KAKENHI-PROJECT-24500852
[Journal Article] Transplantation of neural crest-like cells derived from induced pluripotent stem cells improves diabetic polyneuropathy in mice2013
- Author(s)
  Okawa T, Kamiya H, Himeno T, Kato J, Seino Y, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Ozaki N, Cheng Z, Kito T, Suzuki H, Ito S, Oiso Y, Nakamura J, Isobe K
- Journal Title
  
  Cell Transplant
  
  Volume: 22(10) Pages: 1767-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] iPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis.2013
- Author(s)
  Kito T, Shibata R, Ishii M, Suzuki H, Himeno T, Kataoka Y, Yamamura Y, Yamamoto T, Nishio N, Ito S, Numaguchi Y, Tanigawa T, Yamashita JK, Ouchi N, Honda H, Isobe K, Murohara T.
- Journal Title
  
  Sci Rep
  
  Volume: 11:3 Issue: 1 Pages: 1418-1418
- DOI
  10.1038/srep01418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144, KAKENHI-PROJECT-23390207, KAKENHI-PROJECT-23390208, KAKENHI-PROJECT-23790845, KAKENHI-PROJECT-24659384, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-25860595
[Journal Article] iPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis2013
- Author(s)
  Kito T, Shibata R, Ishii M, Suzuki H, Himeno T, Kataoka Y, Yamamura Y, Yamamoto T, Nishio N, Ito S, Numaguchi Y, Tanigawa T, Yamashita JK, Ouchi N, Honda H, Isobe K, Murohara T
- Journal Title
  
  Sci Rep
  
  Volume: 3 Pages: 1418-1418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Characteristics of cardiac aging in C57BL/6 mice.2013
- Author(s)
  Cheng Z, Ito S, Nishio N, Thanasegaran S, Fang H, Isobe K.
- Journal Title
  
  Exp Gerontol
  
  Volume: 48(3) Issue: 3 Pages: 341-348
- DOI
  10.1016/j.exger.2013.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144, KAKENHI-PROJECT-25293166
[Journal Article] Transplantation of neural crest like cells derived from induced pluripotent stem cells improves diabetic polyneuropathy in mice2013
- Author(s)
  Okawa T, Kamiya H, Himeno T, Kato J, Seino Y, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Ozaki N, Cheng Z, Kito T, Suzuki H, Ito S, Nakamura J, Isobe K
- Journal Title
  
  Cell Transplant
  
  Volume: 22 Pages: 1763-1783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591303
[Journal Article] Loss of GADD34 induces early age-dependent deviation to the myeloid lineage2013
- Author(s)
  Nishio N, Ito S, Isobe K
- Journal Title
  
  Immunol Cell Biol
  
  Volume: Feb;92(2) Pages: 170-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Mesenchymal stem cell-like cells derived from mouse induced pluripotent stem cells ameliorate diabetic polyneuropathy in mice.2013
- Author(s)
  Himeno T, Kamiya H, Naruse K, Cheng Z, Ito S, Kondo M, Okawa T, Fujiya A, Kato J, Suzuki H, Kito T, Hamada Y, Oiso Y, Isobe K, Nakamura J.
- Journal Title
  
  Biomed Res Int
  
  Volume: - Pages: 259187-259187
- DOI
  10.1155/2013/259187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591303, KAKENHI-PROJECT-25293166
[Journal Article] Characteristics of cardiac aging in C57BL/6 mice2013
- Author(s)
  Cheng Z, Ito S, Nishio N, Thanasegaran S, Fang H, Isobe K
- Journal Title
  
  Exp Gerontol
  
  Volume: Mar;48(3) Pages: 341-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Loss of GADD34 induces early age-dependent deviation to the myeloid lineage.2013
- Author(s)
  Nishio N, Ito S, Isobe K.
- Journal Title
  
  Immunol Cell Biol.
  
  Volume: 92 Issue: 2 Pages: 170-80
- DOI
  10.1038/icb.2013.78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] No immunogenicity of IPS cells in syngeneic host studied by in vivo injection and 3D scaffold experiments.2013
- Author(s)
  Thanasegaran S, Cheng Z, Ito S, Nishio N, Isobe K.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2013 Pages: 378207-378213
- DOI
  10.1155/2013/378207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] Establishment of Self-Renewable GM-CSF-Dependent Immature Macrophages In Vitro from Murine Bone Marrow2013
- Author(s)
  Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K
- Journal Title
  
  PLoS One
  
  Volume: Oct 4 8(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Establishment of self-renewable GM-CSF-dependent immature macrophages in vitro from murine bone marrow.2013
- Author(s)
  Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 10 Pages: e76943-e76943
- DOI
  10.1371/journal.pone.0076943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] No immunogenicity of IPS cells in syngeneic host studied by in vivo injection and 3D scaffold experiments2013
- Author(s)
  Thanasegaran S, Cheng Z, Ito S, Nishio N, Isobe K
- Journal Title
  
  Biomed Res Int
  
  Volume: 2013 Pages: 378207-378207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Transplantation of neural crest like cells derived from induced pluripotent stem cells improves diabetic polyneuropathy in mice.2013
- Author(s)
  Okawa T, Kamiya H, Himeno T, Kato J, Seino Y, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Ozaki N, Cheng Z, Kito T, Suzuki H, Ito S, Nakamura J, Isobe K
- Journal Title
  
  Cell Transplant
  
  Volume: 22 Pages: 1763-1783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591303
[Journal Article] Up-regulation of Gr1+CD11b+ cell population in the spleen of NaClO-administered mice works to repair skin wounds.2012
- Author(s)
  M. Hara N. Nishio S. Ito M. Akiyama K. Isobe
- Journal Title
  
  BioDiscivery
  
  Volume: 2:1 Pages: 2050-2966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Aging in the mouse and perspectives of rejuvenation through induced pluripotent stem cells (iPSCs)2012
- Author(s)
  Isobe K, Cheng Z, Ito S, Nishio N
- Journal Title
  
  Results Probl Cell Differ
  
  Volume: 55 Pages: 413-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Comparative angiogenic activities of induced pluripotent stem cells derived from young and old mice.2012
- Author(s)
  Suzuki H, Shibata R, Kito T, Yamamoto T, Ishii M, Nishio N, Ito S, Isobe K, Murohara T.
- Journal Title
  
  PLoS One
  
  Volume: 7(6) Issue: 6 Pages: e39562-e39562
- DOI
  10.1371/journal.pone.0039562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Aging in the mouse and perspectives of rejuvenation through induced pluripotent stem cells (iPSCs).2012
- Author(s)
  Isobe K, Cheng Z, Ito S, Nishio N.
- Journal Title
  
  Results Probl Cell Differ
  
  Volume: 55 Pages: 413-427
- DOI
  10.1007/978-3-642-30406-4_21
- ISBN
  9783642304057, 9783642304064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Transplantation of Neural Crest Like Cells Derived from induced Pluripotent Stem Cells Improves Diabetic Polyneuropathy in Mice.2012
- Author(s)
  Okawa T, Kamiya H, Himeno T, Kato J, Seino Y, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Ozaki N, Cheng Z, Kito T, Suzuki H, Ito S, Oiso Y, Nakamura J, Isobe KI.
- Journal Title
  
  Cell Transplant
  
  Volume: 22(10） Issue: 10 Pages: 1767-1783
- DOI
  10.3727/096368912x657710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Comparative angiogenic activities of induced pluripotent stem cells derived from young and old mice2012
- Author(s)
  Murohara T. CSuzuki H, Shibata R, Kito T, Yamamoto T, Ishii M, Nishio N, Ito S, Isobe K
- Journal Title
  
  PLoS One
  
  Volume: 7(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice2011
- Author(s)
  Miura H, Ando Y, Noda Y, Isobe K, Ozaki N
- Journal Title
  
  Stress
  
  Volume: 14 Pages: 262-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Establishment of induced pluripotent stem cells from aged mice using bone marrow-derived myeloid cells2011
- Author(s)
  Cheng Z, Ito S, Nishio N, Xiao H, Zhang R, Suzuki H, Okawa Y, Murohara T, Isobe K
- Journal Title
  
  J Mol Cell Biol
  
  Volume: Apr;3(2) Pages: 91-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] CD8+CD122+ regulatory T cells (Tregs) and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis2011
- Author(s)
  Endharti AT, Okuno Y, Shi Z, Misawa N, Toyokuni S, Ito M, Isobe K, Suzuki H
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 41-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation2011
- Author(s)
  Uddin MN, Ito S, Nishio N, Suganya T, Isobe K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: Apr 22;407(4) Pages: 692-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Differentiation of induced pluripotent stem cells to thymic epithelial cells by phenotype2011
- Author(s)
  Inami Y, Yoshikai T, Ito S, Nishio N, Suzuki H, Sakurai H, Isobe K
- Journal Title
  
  Immunol Cell Biol
  
  Volume: 89 Pages: 314-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Dextran sulphate sodium increases splenic Gr1(+)CD11b(+) cells which accelerate recovery from colitis following intravenous transplantation2011
- Author(s)
  Zhang R, Ito S, Nishio N, Cheng Z, Suzuki H, Isobe K
- Journal Title
  
  Clin Exp Immunol
  
  Volume: Jun;164(3) Pages: 417-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Up-regulation of Gr1+CD11b+ population in spleen of dextran sulfate sodium administered mice works to repair colitis2011
- Author(s)
  Zhang R, Ito S, Nishio N, Cheng Z, Suzuki H, Isobe K
- Journal Title
  
  Inflamm Allergy Drug Targets
  
  Volume: Feb;10(1) Pages: 39-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] 老化と再生-老化マウスからのiPS細胞の樹立2010
- Author(s)
  磯部健一、Zhao Cheng, 伊藤佐知子、西尾尚美
- Journal Title
  
  基礎老化研究
  
  Volume: 34 Pages: 33-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Intra-bone marrow bone marrow transplantation rejuvenates the B-cell lineage in aged mice2010
- Author(s)
  Hida D, Ishiguro N, Haneda M, Ishida Y, Suzuki H, Isobe K.
- Journal Title
  
  Immunol Cell Biol. 88(1)
  
  Pages: 87-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article]2010
- Author(s)
  H.Sakurai, Y, Inami, N.Nishio, S.Ito, T.Yoshikai, H.Suzuki, K.Isobe
- Journal Title
  
  Specific serum-free conditions can differentiate mouse embryonic stem cells into osteochondrogenic and myogenic progenitors(Micro Electronic and Mechanical Systems, ISBN 978-953-307-027-8)
  
  Pages: 107-112
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Toxic effects of D-galactose on thymus and spleen that resemble aging2010
- Author(s)
  Uddin MN, Nishio N, Ito S, Suzuki H, Isobe K
- Journal Title
  
  J Immunotoxicol
  
  Volume: 7(3) Pages: 165-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Intra-bone marrow bone marrow transplantation rejuvenates the B-cell lineage in aged mice2010
- Author(s)
  Hida D, Ishiguro N, Haneda M, Ishida Y, Suzuki H, Isobe K
- Journal Title
  
  Immunol Cell Biol 88(1)
  
  Pages: 87-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Therapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells2010
- Author(s)
  Suzuki H, Shibata R, Kito T, Ishii M, Li P, Yoshikai T, Nishio N, Ito S, Numaguchi Y, Yamashita JK, Murohara T, Isobe K
- Journal Title
  
  BMC Cell Biol
  
  Volume: 11 Pages: 72-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article]2010
- Author(s)
  磯部健一
- Journal Title
  
  免疫系の加齢変化 (新老年学)(東京大学出版会)
  
  Pages: 169-184
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] GADD34 suppresses wound healing by upregulating expression of myosin IIA2010
- Author(s)
  Tanaka C, Ito S, Nishio N, Kodera Y, Sakurai H, Suzuki H, Nakao A, Isobe K
- Journal Title
  
  Transgenic Res
  
  Volume: 19 Pages: 637-645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144
[Journal Article] Development of peptide arrays for detection of IgE-binding epitopes in cow's milk allergens2009
- Author(s)
  Matsumoto N, Okochi M, Matsushima M, Ogawa A, Takase T, Yoshida Y, Kawase M, Isobe K, Kawabe T, Honda H
- Journal Title
  
  J Biosci Bioeng 107(3)
  
  Pages: 324-30
- NAID
  110007160760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Hemoglobin induces the expression of indoleamine 2, 3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species2009
- Author(s)
  Ogasawara N, Oguro T, Sakabe T, Matsushima M, Takikawa O, Isobe K, Nagase F
- Journal Title
  
  J Cell Biochem 108(3)
  
  Pages: 716-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Peptide array-based analysis of the specific IgE and IgG4 in cow's milk allergens and its use in allergy evaluation2009
- Author(s)
  Matsumoto N, Okochi M, Matsushima M, Kato R, Takase T, Yoshida Y, Kawase M, Isobe K, Kawabe T, Honda H
- Journal Title
  
  Peptides 30(10)
  
  Pages: 1840-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Shifting the balance of brain tryptophan metabolism elicited by isolation housing and systemic administration of lipopolysaccharide in mice2009
- Author(s)
  Miura H, Shirokawa T, Isobe K, Ozaki N.Stress
- Journal Title
  
  Stress 12(3)
  
  Pages: 206-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Development of peptide arrays for detection of IgE-binding epitopes in cow's milk allergens2009
- Author(s)
  Matsumoto N, Okochi M, Matsushima M, Ogawa A, Takase T, Yoshida Y, Kawase M, Isobe K, Kawabe T, Honda H.
- Journal Title
  
  J Biosci Bioeng. 107(3)
  
  Pages: 324-330
- NAID
  110007160760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article]2009
- Author(s)
  Sakurai H, Inami Y, Tamamura Y, Yoshikai T, Sehara-Fujisawa A, Isobe K
- Journal Title
  
  Stem Cell Res 3(2-3)
  
  Pages: 157-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Antibodies to wounded tissue enhance cutaneous wound healing2009
- Author(s)
  Nishio N, Ito S, Suzuki H, Isobe K.
- Journal Title
  
  Immunology 128(3)
  
  Pages: 369-380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Peptide array-based analysis of the specific IgE and IgG4 in cow's milk allergens and its use in allergy evaluation2009
- Author(s)
  Matsumoto N, Okochi M, Matsushima M, Kato R, Takase T, Yoshida Y, Kawase M, Isobe K, Kawabe T, Honda H.
- Journal Title
  
  Peptides 30(10)
  
  Pages: 1840-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg2009
- Author(s)
  Shi Z, Okuno Y, Rifa'i M, Endharti AT, Akane K, Isobe K, Suzuki H
- Journal Title
  
  Eur J Immunol 39(8)
  
  Pages: 2106-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Injection of bleomycin in newborn mice induces autoimmune sialitis that is transferred by CD4 T cells. mmunol2009
- Author(s)
  Ishikawa H, Ito S, Nishio N, Yuzawa Y, Matsuo S, Isobe K
- Journal Title
  
  Cell Biol 87(4)
  
  Pages: 351-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Injection of bleomycin in newborn mice induces autoimmune sialitis that is transferred by CD4 T cells2009
- Author(s)
  Ishikawa H, Ito S, Nishio N, Yuzawa Y, Matsuo S, Isobe K.
- Journal Title
  
  Immunol Cell Biol. 87(4)
  
  Pages: 351-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Induction of autoimmunity in a bleomycin-induced murine model of experimental systemic sclerosis: an important role for CD4+ T cells2009
- Author(s)
  Ishikawa H, Takeda K, Okamoto A, Matsuo S, Isobe K
- Journal Title
  
  J Invest Dermatol 129(7)
  
  Pages: 1688-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Shifting the balance of brain tryptophan metabolism elicited by isolation housing and systemic administration of lipopolysaccharide in mice2009
- Author(s)
  Miura H, Shirokawa T, Isobe K, Ozaki N
- Journal Title
  
  Stress 12(3)
  
  Pages: 206-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Bidirectional induction toward paraxial mesodermal derivatives from mouse ES cells in chemically defined medium2009
- Author(s)
  Sakurai H, Inami Y, Tamamura Y, Yoshikai T, Sehara-Fujisawa A, Isobe K.
- Journal Title
  
  Stem Cell Res. 3(2-3)
  
  Pages: 157-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg2009
- Author(s)
  Shi Z, Okuno Y, Rifa'i M, Endharti AT, Akane K, Isobe K, Suzuki H.
- Journal Title
  
  Eur J Immunol. 39(8)
  
  Pages: 2106-2119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Induction of autoimmunity in a bleomycin-induced murine model of experimental systemic sclerosis : an important role for CD4+ T cells2009
- Author(s)
  Ishikawa H, Takeda K, Okamoto A, Matsuo S, Isobe K.
- Journal Title
  
  J Invest Dermatol. 129(7)
  
  Pages: 1688-1695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] 免疫機能低下と老化関連疾患2009
- Author(s)
  磯部健一, 西尾尚美, 伊藤佐知子
- Journal Title
  
  日本臨床 67(7)
  
  Pages: 1327-1331
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species2009
- Author(s)
  Ogasawara N, Oguro T, Sakabe T, Matsushima M, Takikawa O, Isobe K, Nagase F.
- Journal Title
  
  J Cell Biochem. 108(3)
  
  Pages: 716-725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Antibodies to wounded tissue enhance cutaneous wound healing2009
- Author(s)
  Nishio N, Ito S, Suzuki H, Isobe K
- Journal Title
  
  Immunology 128(3)
  
  Pages: 369-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] 免疫機能低下と老化関連疾患2009
- Author(s)
  磯部健一、西尾尚美、伊藤佐知子
- Journal Title
  
  日本臨床 67(7)
  
  Pages: 1327-133
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Inhibition of reactive oxygen species down-regulates protein synthesis in RAW 264.72008
- Author(s)
  Kimura K, Ito S, Nagino M, Isobe K.
- Journal Title
  
  Biochem Biophys Res Commun 372(1)
  
  Pages: 272-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease2008
- Author(s)
  Kobayashi T, Okamoto S, Hisamatsu T, Kamada N, Chinen H, Saito R, Kitazume MT, Nakazawa A, Sugita A, Koganei K, Isobe K, Hibi T.
- Journal Title
  
  Gut. 57(12)
  
  Pages: 1682-1689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Thymic involution correlates with severe ulcerative colitis induced by oral administration of dextran sulphate sodium in C57BL/6 mice but not in BALB/c mice2008
- Author(s)
  Suzuki H, Shi Z, Okuno Y, Isobe K.
- Journal Title
  
  Hum Immunol. 69(11)
  
  Pages: 751-754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Changes in brain tryptophan metabolism elicited by ageing, social environment, and psychological stress in mice2008
- Author(s)
  Miura H, Ozaki N, Shirokawa T, Isobe K.
- Journal Title
  
  Stress. 11(2)
  
  Pages: 160-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Cinnabarinic acid generated from 3-hydroxyanthranilic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase2008
- Author(s)
  Hiramatsu R, Hara T, Akimoto H, Takikawa O, Kawabe T, Isobe K, Nagase F
- Journal Title
  
  J Cell Biochem 103(1)
  
  Pages: 42-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Diazotization of kynurenine by acidified nitrite secreted from indoleamine 2, 3-dioxygenase-expressing myeloid dendritic cells2008
- Author(s)
  Hara T, Yamakura F, Takikawa O, Hiramatsu R, Kawabe T, Isobe K, Nagase F
- Journal Title
  
  J Immunol Methods 332(1-2)
  
  Pages: 162-9
- NAID
  120001164493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Thymic involution correlates with severe ulcerative colitis induced by oral administration of dextran sulphate sodium in C57BL/6 mice but not in BALB/c mice2008
- Author(s)
  Sasaki S, Ishida Y, Nishio N, Ito S, Isobe K.
- Journal Title
  
  Inflammation 31(5)
  
  Pages: 319-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Importance of CD80/CD86-CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells2008
- Author(s)
  Shi Z, Rifa'i M, Lee YH, Shiku H, Isobe K, Suzuki H.
- Journal Title
  
  Immunology 124(1)
  
  Pages: 121-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease2008
- Author(s)
  Kobayashi T, Okamoto S, Hisamatsu T, Kamada N, Chinen H, Saito R, Kitazume MT, Nakazawa A, Sugita A, Koganei K, Isobe K, Hibi T
- Journal Title
  
  Gut 57(12)
  
  Pages: 1682-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Importance of CD80/CD86-CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells2008
- Author(s)
  Shi Z, Rifa'i M, Lee YH, Shiku H, Isobe K, Suzuki H
- Journal Title
  
  Immunology 124(1)
  
  Pages: 121-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Diazotization of kynurenine by acidified nitrite secreted from indolea mine 2, 3-dioxygenase-expressing myeloid dendritic cells2008
- Author(s)
  Hiramatsu R, Hara T, Akimoto H, Takikawa O, Kawabe T, Isobe K, Nagase F.
- Journal Title
  
  J Cell Biochem. 103
  
  Pages: 42-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells2008
- Author(s)
  Rifa'i M, Shi Z, Zhang SY, Lee YH, Shiku H, Isobe K, Suzuki H
- Journal Title
  
  Int Immunol 20(7)
  
  Pages: 937-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Paraxial mesodermal progenitors derived from mouse embryonic stem cells contribute to muscle regeneration via differentiation into muscle satellite cells2008
- Author(s)
  Sakurai H, Okawa Y, Inami Y, Nishio N, Isobe K
- Journal Title
  
  Stem Cells 26(7)
  
  Pages: 1865-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells2008
- Author(s)
  Rifa'i M, Shi Z, Zhang SY, Lee YH, Shiku H, Isobe K, Suzuki H.
- Journal Title
  
  Int Immunol. 20(7)
  
  Pages: 937-947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Neutrophil depletion delays wound repair in aged mice2008
- Author(s)
  Nishio N, Okawa Y, Sakurai H, Isobe K
- Journal Title
  
  Age (Dordr) 30(1)
  
  Pages: 11-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Overexpression of indoleamine 2, 3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model2008
- Author(s)
  Yoshida N, Ino K, Ishida Y, Kajiyama H, Yamamoto E, Shibata K, Terauchi M, Nawa A, Akimoto H, Takikawa O, Isobe K, Kikkawa F
- Journal Title
  
  Clin Cancer Res 14(22)
  
  Pages: 7251-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Diazotization of kynurenine by acidified nitrite secreted from indolea mine 2, 3-dioxygenase-expressing myeloid dendritic cells2008
- Author(s)
  Hara T, Yamakura F, Takikawa O, Hiramatsu R, Kawabe T, Isobe K, Nagase F.
- Journal Title
  
  J Immunol Methods. 332
  
  Pages: 162-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] High-affinity uptake of kynurenine and nitric oxide-mediated inhibition of indoleamine 2, 3-dioxygenase in bone marrow-derived myeloid dendritic cells2008
- Author(s)
  Hara T, Ogasawara N, Akimoto H, Takikawa O, Hiramatsu R, Kawabe T, Isobe K, Nagase F
- Journal Title
  
  Immunol Lett 116(1)
  
  Pages: 95-102
- NAID
  120001164494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model2008
- Author(s)
  Yoshida N, Ino K, Ishida Y, Kajiyama H, Yamamoto E, Shibata K, Terauchi M, Nawa A, Akimoto H, Takikawa O, Isobe K, Kikkawa F
- Journal Title
  
  Clin Cancer Res 14(22)
  
  Pages: 7251-7259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Paraxial mesodermal progenitors derived from mouse embryonic stem cells contribute to muscle regeneration via differentiation into muscle satellite cells2008
- Author(s)
  Sakurai H, Okawa Y, Inami Y, Nishio N, Isobe K.
- Journal Title
  
  Stem Cells. 26(7)
  
  Pages: 1865-1873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Are CD8+CD122+ cells regulatory T cells or memory T cells?2008
- Author(s)
  Suzuki H, Shi Z, Okuno Y, Isobe K
- Journal Title
  
  69(11)
  
  Pages: 751-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] GADD34 induces p21 expression and cellular senescence2007
- Author(s)
  Minami K, Inoue H, Terashita T, Kawakami T, Watanabe R, Haneda M, Isobe K, Okabe H, Chano T.
- Journal Title
  
  Oncol Rep. 17
  
  Pages: 1481-1485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Large defects of type I allergic response in telomerase reverse transcriptase knockout mice2007
- Author(s)
  Ujike-Asai A, Okada A, Du Y, Maruyama M, Yuan X, Ishikawa F, Motoo Y, Isobe K, Nakajima H.
- Journal Title
  
  J Leukoc Biol. Aug 82
  
  Pages: 429-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Suppression of Viral Replication by Stress-inducible GADD34 via the mTOR Pathway2007
- Author(s)
  Minami K, Tambe Y, Watanabe R, Isono T, Haneda M, Isobe KI, Kobayashi T, Hino O, Okabe H, Chano T, Inoue H.
- Journal Title
  
  J Virol. 81
  
  Pages: 11106-11115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Induction of matrix metalloproteinases (MMP3, MMP12 and MMP13) expression in the microglia by amyloid-beta stimulation via the PI3 K/Akt pathway2007
- Author(s)
  Ito S, Kimura K, Haneda M, Ishida Y, Sawada M, Isobe K.
- Journal Title
  
  Exp Gerontol. 42
  
  Pages: 532-537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Journal Article] Age-dependent changes in dopaminergic projections from the substanti a nigra pars compacta to the neostriatum2007
- Author(s)
  Ishida Y, Okawa Y, Ito S, Shirokawa T, Isobe K.
- Journal Title
  
  Neurosci Lett. 2007
  
  Pages: 257-561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390191
[Patent] ミエロ系細胞を含有する抗炎症剤及びその用途2011
- Inventor(s)
  磯部健一
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Filing Date
  2011-12-08
- Overseas
- Data Source
  KAKENHI-PROJECT-22390144
[Patent] 誘導多能性幹細胞の作成法2011
- Inventor(s)
  磯部健一
- Industrial Property Rights Holder
  名古屋大学
- Filing Date
  2011-03-30
- Overseas
- Data Source
  KAKENHI-PROJECT-22390144
[Patent] 多能性幹細胞を胸腺上皮細胞へ分化誘導する方法2010
- Inventor(s)
  磯部健一
- Industrial Property Rights Holder
  名古屋大学
- Filing Date
  2010-05-25
- Overseas
- Data Source
  KAKENHI-PROJECT-22390144
[Patent] ミエロ系細胞を含有する抗炎症剤及びその用途2010
- Inventor(s)
  磯部健一
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2010-120967
- Filing Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-22390144
[Patent] ヒト全身性強皮症動物モデルの作製方法、ヒト全身性強皮症動物モデル及びその用途2007
- Inventor(s)
  磯部健一石川英昭
- Industrial Property Rights Holder
  名古屋大学
- Filing Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-19390191
[Patent] ヒト全身性強皮症動物モデルの作製方法、ヒト全身性強皮症動物モデル及びその用途2007
- Inventor(s)
  磯部健一, 石川英昭
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Filing Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] GADD34発現の老化による変化；KOマウスを使用した解析2023
- Author(s)
  西尾尚美、磯部健一、長谷川忠男
- Organizer
  第46回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-19K11687
[Presentation] GADD34発現の老化による変化；KOマウスを使用した解析2023
- Author(s)
  西尾尚美、磯部健一、長谷川忠男
- Organizer
  第46回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-23K10932
[Presentation] Adult mice fed only heneggs are alive healthy until aged, but pups nursed by egg-only mice died early.2022
- Author(s)
  NAOMI Nishio, KEN-ICHI Isobe
- Organizer
  日本基礎老化学会
- Data Source
  KAKENHI-PROJECT-19K11687
[Presentation] GADD34 の機能解析2022
- Author(s)
  磯部健一、長谷川忠男、○西尾尚美
- Organizer
  第16回日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-19K11687
[Presentation] Adult mice fed only heneggs are alive healthy until aged, but pups nursed by egg-only mice died early.2022
- Author(s)
  Naomi Nishio, Ken-ich Isobe
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-19K11687
[Presentation] Mice fed only heneggs are alive healthy until aged.2021
- Author(s)
  NAOMI Nishio, KEN-ICHI Isobe
- Organizer
  日本基礎老化学会
- Data Source
  KAKENHI-PROJECT-19K11687
[Presentation] 免疫老化とリュウマチ疾患2019
- Author(s)
  磯部健一
- Organizer
  基礎と臨床を結ぶ分子病態研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05280
[Presentation] Female GADD34 mice develop inflammation and hepatocellular carcinoma by aging.2017
- Author(s)
  Naomi Nishio, Tadao Hasegawa, Ken-ich Isobe.
- Organizer
  第40回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-16H05280
[Presentation] GADD34 works to 　suppress obesity-induced 　Metabolic Diseases including 　type 2 diabetes and NASH2.2016
- Author(s)
  西尾尚美、長谷川忠男、磯部健一
- Organizer
  第86回日本衛生学会学術総会
- Place of Presentation
  旭川市旭川市民文化会館、北海道旭川市
- Year and Date
  2016-05-11
- Data Source
  KAKENHI-PROJECT-16H05280
[Presentation] GADD34 works to 　suppress obesity-induced 　Metabolic Diseases including 　type 2 diabetes and NASH2.2016
- Author(s)
  西尾尚美、長谷川忠男、磯部健一
- Organizer
  第86回日本衛生学会学術総会
- Place of Presentation
  旭川市旭川市民文化会館
- Year and Date
  2016-05-11
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Therapeutic effects of antibiotics on colitiss and colon carcinogensis in AOM/DSS-induced murine colitiss-associated colon cancer model.2015
- Author(s)
  Tanaka Y, Ito S, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター　北海道、札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works to suppress obesity-induced metabolic disease including type 2 diabetes and NASH-22015
- Author(s)
  Nishio N. Isobe K.
- Organizer
  第38回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ科学館　愛知県、知多郡東浦町
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 promotes colon carcinogensis through upregulating IL-6-STAT3 signaling.2015
- Author(s)
  Ito S, Tanaka Y, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター　北海道、札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works to suppress obesity and fatty acid-induced insulin resistance.2015
- Author(s)
  Nishio N. Isobe K.
- Organizer
  19th International Conference of FFC (Kobe)
- Place of Presentation
  神戸大学　神戸
- Year and Date
  2015-11-17
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] 皮膚幹細胞球状凝集体由来神経前駆細胞を用いた糖尿病多発神経障害(DPN)移植治療の検討2014
- Author(s)
  近藤正樹、神谷英紀、姫野龍仁、大川哲司、成瀬桂子、濱田洋司、西尾尚美、伊藤佐知子、大磯ユタカ、磯部健一、中村二郎
- Organizer
  第28回日本糖尿病・肥満動物学会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-23591303
[Presentation] Acrolein-induced lung cell death and macrophages functional changes.2014
- Author(s)
  Sun Yang,Sachiko Ito, Yuriko Tanaka, Lintao Liu, Nana Chin, Naomi Nishioand Ken-ichi Isobe
- Organizer
  The japanese-Korean Lymphoreticular workshop 2014 in conjunction with the 5th Asian Hematopathology symposium
- Place of Presentation
  名古屋大学附属病院(名古屋市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Injection of GR-1+CD11ｂ+ cells to inflammation-induced colon cancer reduces tumor formation2014
- Author(s)
  Yutriko Tanaka, Sachiko Ito, Reina Oshino, Naomi Nishio, Ken-ichi Isobe
- Organizer
  The japanese-Korean Lymphoreticular workshop 2014 in conjunction with the 5th Asian Hematopathology symposium
- Place of Presentation
  名古屋大学附属病院(名古屋市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Negative Regulation of GADD34 on Myofibroblasts during Cutaneous Wound Healing2013
- Author(s)
  Lintao Liu, Naomi Nishio, Sachiko Ito, Yuriko Tanaka, Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Negative Regulation of GADD34 on Myofibroblasts during Cutaneous Wound Healing2013
- Author(s)
  Lintao Liu, Naomi Nishio,Sachiko Ito, Yuriko Tanaka and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34は高脂肪食による脂肪蓄積を予防する2013
- Author(s)
  西尾尚美, 伊藤佐知子、磯部　健一
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪大学中之島センター、大阪国際会議場（大阪市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Toward personalized therapies by using aged patients own iPSCs (model experiments)2013
- Author(s)
  Ken-ichi Isobe, Sachiko Ito, Naomi Nishio, Yuriko Tanaka, Zhao Chang, Tetsuji Okawa, Suganya Thanasegaran
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪国際会議場(大阪市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Loss of GADD34 induces fatty liver diseases, type II Diabetes2013
- Author(s)
  NISHIO Naomi, ITO Sachiko, ISOBE Ken-ichi
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] GM－CSF依存的に長期増殖するマウス骨髄由来マクロファージ細胞の解析２2013
- Author(s)
  伊藤佐知子、田中ゆりこ、西尾尚美、Cheng Zhao, 磯部健一
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪大学中之島センター、大阪国際会議場(大阪市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] The role of macrophages in tumorigenesis.2013
- Author(s)
  Yuriko　TANAKA,, Sachiko Ito, Naomi Nishio and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Establishment of macrophage stem-like cells from murine bone marrow2013
- Author(s)
  Sachiko Ito, Naomi Nishio,Yuriko Tanaka and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Aged-iPS細胞の免疫原性2013
- Author(s)
  Tanasegaran Suganya, Zhao Cheng,伊藤佐知子、西尾尚美、磯部健一
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪国際会議場(大阪市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Acrolein-induced lung cell death and macrophages functional changes2013
- Author(s)
  Yang Sun,, Sachiko Ito, Yuriko Tanaka, Naomi Nishio and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Loss of GADD34 induces fatty liver diseases, type II Diabetes2013
- Author(s)
  NISHIO Naomi,Sachiko Ito and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] iPS細胞の免疫原生とaging2013
- Author(s)
  Thanasegaran Suganya、, Zhao Cheng, 伊藤佐知子、西尾直美、磯部　健一
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪大学中之島センター、大阪国際会議場(大阪市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Transplantation of Induced neural crest cells from spheroidal dermal stem cells improves diabetic polyneuropathy in mice2013
- Author(s)
  Kondo M, Kamiya H, Himeno T, Kato J, Okawa T, Kato J, Fujiya A, Hamada Y, Naruse K, Nishio N, Ito S, Oiso Y, Isobe K, Nakamura J
- Organizer
  The 73th the American Diabetes Association Scientific Sessions
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23591303
[Presentation] GM-CSF依存的に長期増殖するマウス骨髄由来マクロファージの解析2012
- Author(s)
  伊藤　佐知子、田中　ゆりこ、西尾　尚美、磯部　健一
- Organizer
  第35回日本基礎老化学会
- Place of Presentation
  東邦大学習志野キャンパス(船橋市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Immunogenicity of iPSCs from aged mice and MEF2012
- Author(s)
  Thanasegaran Suganya, Zhao Cheng, Sachiko ito, Naomi Nishio, He Feng, Ken-ichi Isobe
- Organizer
  第3回ワークショップSynthetic Immunology
- Place of Presentation
  京都大学芝蘭会館(京都市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Establishment of neutrophil-lineage stem cells from C57BL/6 mice.2012
- Author(s)
  Naomi Nishio, Sachiko Ito, Yuriko Tanaka and Ken-ichi Isobe
- Organizer
  MHS2012 & Micro-Nano Global COE
- Place of Presentation
  名古屋大学東山キャンパス(名古屋市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] マウスiPS細胞由来神経堤細胞移植の糖尿病性多発神経障害に対する治療効果の検討2012
- Author(s)
  大川哲司、神谷英紀、成瀬恵子、磯部健一、中村二郎
- Organizer
  第26回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591303
[Presentation] No immunogenicity of teratoma derived from iPSCs2012
- Author(s)
  Thanasegaran Suganya, Ken-ichi Isobe
- Organizer
  第7回マイクロナノGCOE-UCLA合同シンポジウム
- Place of Presentation
  ホテルレオパレス札幌(札幌市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Toward personalized cell therapy byusing patient own iPSCs2012
- Author(s)
  磯部　健一
- Organizer
  第7回マイクロナノGCOE-UCLA合同シンポジウム
- Place of Presentation
  ホテルレオパレス札幌（札幌市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] GADD34は免疫老化を抑制する。―骨髄好中球前駆細胞の増殖抑制―2012
- Author(s)
  西尾　尚美、伊藤　佐知子、磯部　健一
- Organizer
  第35回日本基礎老化学会
- Place of Presentation
  東邦大学習志野キャンパス(船橋市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Thymic aging and differentiation of induced pluripotent stem cells to thymic epithelial cells for future personalized cell therapy.2012
- Author(s)
  Motohito Okabe, Sachiko Ito, Naomi Nishio, Moammad Nizam Uddin, Yuta Inami, Tohru Yoshikai, Lintao Liu, Thanasegaran Suganya, Ken-ichi Isobe
- Organizer
  The 35th Japan Society for Biomedical Gerontology Symposiium and Micro -Nano Global COE
- Place of Presentation
  名古屋大学鶴舞キャンパス(名古屋市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] 3D-aggregated Dermal Stem Cells with Partial-pluripotency2012
- Author(s)
  Masaki Kondo, Hideki Kamiya, Tetsuji Okawa, Sachiko Ito, Naomi Nishio,Tatsuhito Himeno, Yutaka Oiso, Jiro Nakamura and Ken-ichi Isobe
- Organizer
  MHS2012 & Micro-Nano Global COE
- Place of Presentation
  名古屋大学東山キャンパス(名古屋市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] The expression of GADD34is induced by various TLR kligands and affect the cytokine productions via TLR signaling2012
- Author(s)
  ITO Sachiko, NISHIO Naomi, TANAKA Yuriko, ISOBE Ken-ichi
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] 老化マウス由来iPS細胞のキメラマウスでの解析2012
- Author(s)
  Zhao Cheng, 伊藤　佐知子、西尾　尚美、He Feng, Thanasegaran Suganya, 磯部　健一
- Organizer
  第35回日本基礎老化学会
- Place of Presentation
  東邦大学習志野キャンパス(船橋市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Loss of GADD34 indues early immune aging: impact on the proliferation of neutrophil-lineage cells2012
- Author(s)
  NISHIO Naomi, ITO Sachiko, ISOBE Ken-ichi
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸国際会議場(神戸市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Transplantation of neural progenitor-like cells derived from spheroidal dermal cells improves diabetic polyneuropathy in mice2012
- Author(s)
  Kondo M, Kamiya H, Himeno T, Kato J, Okawa T, Fujiya A, Naruse K, Hamada Y, Nishio N, Ito S, Oiso Y, Isobe K, Nakamura J.
- Organizer
  The 72th the American Diabetes Association Scientific Sessions
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23591303
[Presentation] Possibility to use iPS-technology in age-related diseases2012
- Author(s)
  Zhao Cheng, Sachiko Ito, Naomi Nishio, Thanasegaran Suganya and Ken-ichi Isobe
- Organizer
  MHS2012 & Micro-Nano Global COE
- Place of Presentation
  名古屋大学東山キャンパス(名古屋市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Lack of immunogenicity of induced pluripotent stem cells.2012
- Author(s)
  Thanasegaran Suganya, Zhao Cheng, Sachiko Ito, Naomi Nishio, Ken-ichi Isobe
- Organizer
  The 35th Japan Society for Biomedical Gerontology Symposiium and Micro -Nano Global COE
- Place of Presentation
  名古屋大学鶴舞キャンパス(名古屋市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] The expression of GADD34 is inducesd by various TLR ligands and affect the cytokine productions via TLR signaling2012
- Author(s)
  ITO Sachiko, NISHIO Naomi, TANAKA Yuriko, ISOBE Ken-ichi
- Organizer
  第42回日本免疫学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Estabishment and characterization of aged-iPS for future application of personalized cell therapies.2012
- Author(s)
  Zhao Cheng, Sachiko Ito, Naomi Nishio, He Fang, Thanasegarann Suganya, Ken-ichi Isobe
- Organizer
  The 35th Japan Society for Biomedical Gerontology Symposiium and Micro -Nano Global COE
- Place of Presentation
  名古屋大学鶴舞キャンパス(名古屋市）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Loss of GADD34 induces early immuneaging : impact on the proliferation of neutrophil-lineage cells2012
- Author(s)
  NISHIO Naomi, ITO Sachiko, ISOBE Ken-ichi
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] GADD34はTSC-mTORシグナルを介してLPSによるサイトカイン産生を制御する2011
- Author(s)
  伊藤佐知子、西尾尚美、鈴木治彦、磯部健一
- Organizer
  第40回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] The Possibility of Rejuvenating Aged Tissue Through Application of iPSC Technology2011
- Author(s)
  磯部健一
- Organizer
  第6回名古屋大学‐UCLAシンポジウム
- Place of Presentation
  ロサンゼルス（アメリカ）
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] GADD34遺伝子欠損マウスは老化に伴いミエロ系細胞が異常増殖する2011
- Author(s)
  西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第34回日本基礎老化学会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] 自己iPS細胞で老化変化を若がえらせる試み2010
- Author(s)
  磯部健一
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] Murine model of personalized cell therapy2010
- Author(s)
  磯部健一
- Organizer
  The 5th Nagoya University-UCLA International Symposium
- Place of Presentation
  長野県上田市
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22390144
[Presentation] 樋田大輔西尾尚美伊藤佐知子老化に伴うB細胞発生、分化の変化骨髄内骨髄移植による老化B細胞の若返りの可能性II2009
- Author(s)
  磯部健一
- Organizer
  第32回日本基礎老化学会
- Place of Presentation
  横浜
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Immune status of the D-galactose treated aged mice2009
- Author(s)
  Mohammad Nizam uddin, Nishio N, Ito S, Suzuki H, Isobe K
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] CD8+CD122+ reguratory T lymphocytes prevent experimental inflammatory bowel disease in mice2009
- Author(s)
  Endharti Agustna Tri, Okuno Y, Isobe K. Suzuki H
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 免疫系の老化と疾患、制御の可能性2009
- Author(s)
  磯部健一
- Organizer
  (シンポジウム、免疫機能の制御)第9回日本抗加齢学会
- Place of Presentation
  東京
- Year and Date
  2009-05-28
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 創傷治癒における自己組織結合抗体の役割と年齢変化2009
- Author(s)
  西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第32回日本基礎老化学会
- Place of Presentation
  横浜
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Roles of B cells to wound healing. II2009
- Author(s)
  Naomi Nishio, Sachiko Ito, Haruhiko Suzuki, Ken-ichi Isobe
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Establishment of an easy assay system for human CD8+CXCR3+reguratory T cells2009
- Author(s)
  Okuno Y, Endharti Agustna Tri, Isobe K. Suzuki H
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Thymic structural changes in immune aging by D-Galactose2009
- Author(s)
  Mohammad Nizam uddin, Naomi Nishio, Sachiko Ito, Ken-ichi Isobe
- Organizer
  第32回日本基礎老化学会
- Place of Presentation
  横浜
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Roles of B cells to wound healing2009
- Author(s)
  Nishio N, Ito S, Suzuki H, Isobe K
- Organizer
  II第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 老化に伴うB細胞発生、分化の変化骨髄内骨髄移植による老化B細胞の若返りの可能性II2009
- Author(s)
  磯部健一, 樋田大輔
- Organizer
  第32回日本基礎老化学会
- Place of Presentation
  横浜
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 免疫系の老化と疾患、制御の可能性2009
- Author(s)
  磯部健一
- Organizer
  第9回日本抗加齢学会
- Place of Presentation
  東京
- Year and Date
  2009-05-28
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 粘膜損傷治癒における老化と好中球2008
- Author(s)
  田中千恵、西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第31回基礎老化学会
- Place of Presentation
  松本
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] IL23 differentially regulates Th1/Th17 balance in ulcerative colitis and Croh's disease2008
- Author(s)
  Kobayashi Taku, Okamoto Susumu, Hisamatsu Tadakazu, Kamada Nobuhiko, Chinenn Hirosi, Kanai Takanori, Isobe Ken-ichi, Hibi Toshifumi
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Wound healing is enhanced by autoantibodies generated in response to wounding2008
- Author(s)
  Naomi Nishio, Sachiko Ito, Ken-ichi Isobe
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Bleomycin induces autoimmune sialitis in new born mice2008
- Author(s)
  Ishikawa Hideaki, Ito Sachiko, Kenichi Isobe
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Bidirectional induction toward paraxial mesodermal derivatives from mouse ES cells in chemically defined medium2008
- Author(s)
  H. Sakurai, Y. Inami, Y Tamamura K. Isobe
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 黒質ドーパミン神経細胞の発火様式と線条体への投射系への加齢変化2008
- Author(s)
  石田佳幸、児崎達哉、磯村宣和、春光、張エイ、羽根田正隆、磯部健一
- Organizer
  第31回基礎老化学会
- Place of Presentation
  松本
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 骨髄内骨髄移植による老化B細胞の若返り2008
- Author(s)
  樋田大輔, 羽根田正隆, 石田佳幸, 伊藤佐知子、Nizam uddin, 鈴木治彦, 磯部健一
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Efficient induction of osteogenic and chondrogenic progenitors and myogenic progenitors from mouse ES cells in chemically defined medium2008
- Author(s)
  Hidetoshi Sakurai, Yuta Inami, Naomi Nishio, Tohru Yoshikai, Ken-Ichi Isobe
- Organizer
  2008 International Symposium on Micro-NanoMec hatronics and Human Science
- Place of Presentation
  名古屋
- Year and Date
  2008-10-08
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Human CD8+CXCR3+ cells have the same function as murin CD8+CD122+ reguratory T cells2008
- Author(s)
  Suzuki Haruhiko, Shi Zhe, Okuno Yusuke, Isobe Ken-ichi
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Amyloid-B刺激によるミクログリア活性化と炎症性物質の産生2008
- Author(s)
  伊藤佐知子、磯部健一
- Organizer
  第31回基礎老化学会
- Place of Presentation
  松本
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Analysis of the function of CD8+CD122+ refuratory T cells in tumor immunity2008
- Author(s)
  Okuno Yusuke, Shi Zhe, Isobe Ken-ichi Suzuki Haruhik
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 自己反応性B細胞の創傷治癒における役割と年齢変化2008
- Author(s)
  西尾尚美、田中千恵、伊藤佐知子、磯部健一
- Organizer
  第31回基礎老化学会
- Place of Presentation
  松本
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 老化に伴うB細胞発生、分化の変化骨髄内骨髄移植による老化B細胞の若返りの可能性2008
- Author(s)
  樋田大輔、羽根田正隆、石田佳幸、磯部健一
- Organizer
  第31回基礎老化学会
- Place of Presentation
  松本
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Efficient induction of osteogenic and chondrogenic progenitors and myogenic progenitors from mouse ES cells in chemically defined medium2008
- Author(s)
  Hidetoshi Sakurai, Yuta Inami, Naomi Nishio, Tohru Yoshikai, Ken-Ichi Isobe
- Organizer
  2008 International Symposium on Micro-NanoMechatronics and Human Science
- Place of Presentation
  名古屋
- Year and Date
  2008-10-08
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Phosphorylation of eIF2a was upregulated in BMDC by the stimulation with LPS2007
- Author(s)
  KIMURA Kenya, Ito Sachiko, Haneda Masataka, Isobe Ken-ichi
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] ブレオマイシンによる全身性強皮症モデル2007
- Author(s)
  Hideaki Ishikawa, Kozue Takeda, Masataka HANEDA, ISHIDA Yoshiyuki, Ken-ichi ISOBE
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Phosphorylation of eIF2a was upregulated in BMDC by the stimulation with LPS2007
- Author(s)
  KIMURA Kenya, Ito Sachiko, Haneda Masataka, Isobe Ken-ichi
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Deregulated activation of CD4+CD25- cells in the absence of CD8+CD122+ regulatory T cells despite the presence of CD4+CD25+ Treg in vivo2007
- Author(s)
  SHI Zhe, Rifai Muhaimin, LEE Yong Ho, Isobe Ken-ichi、Suzuki Haruhiko
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] CD8+CD122+制御性T細胞に優先的に反応するモノクローナル抗体の機能的ならびに化学的解析2007
- Author(s)
  Suzuki Haruhiko, SHI Zhe, LEE Yong Ho, Isobe, ken-ichi, Rifai MuhaiminIsobe
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] New mouse model of diffuse type systemic sclerosis; Bleomycin induced2007
- Author(s)
  Hideaki Ishikawa, Kozue Takeda, Masataka HANEDA, ISHIDA Yoshiyuki, Ken-ichi ISOBE
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] T cells in the recovery from experimental autoimmune encephalomyelitis2007
- Author(s)
  LEE Yong Ho, Suzuki Haruhiko, Isobe Ken-ichi
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Neutrophil depletion delays wound repair in aged mice2007
- Author(s)
  Naomi Nishio, Hidetoshi Sakurai, ISHIDA Yoshiyuki, Haneda Masataka, Ken-ichi Isobe
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Neutrophil depletion delays wound repair in aged mice2007
- Author(s)
  Naomi Nishio, Hidetoshi Sakurai, ISHIDA Yoshiyuki, Haneda Masataka, Ken-ichi Isobe
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] 骨髄および胎仔肝由来ミクログリアの神経損傷時の動態について2007
- Author(s)
  石田佳幸, 小林朋子、ニージャム、M., 吉田憲生、羽根田正隆、磯部健一
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Bリンパ球活性化におけるプロテインフォスファターゼ1とGADD34の役割2007
- Author(s)
  Haneda Masataka, isobe Ken-ichi
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Functional and chemical analysis of a monoclonal antibody that preferentially react with CD8+CD122+ regulatory T cells2007
- Author(s)
  Suzuki Haruhiko, SHI Zhe, LEE Yong Ho, Isobe, ken-ichi, Rifai Muhaimin
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] T cells in the recovery from experimental autoimmune encepha lomyelitis2007
- Author(s)
  LEE Yong Ho, Suzuki Haruhiko, Isobe Ken-ichi
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Thymus involution by oral administration of DSS2007
- Author(s)
  SASAKI Makoto, Masataka HANEDA, ISHIDA Yoshiyuki, ISOBE Ken-ichi
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Role of protein phosphatase 1 and GADD34 in B lymphocyte activation2007
- Author(s)
  Haneda Masataka, isobe Ken-ichi
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Role of CD8+CD122+regulatory T cells in experimental autoimmune encepharomyelitis(II)2007
- Author(s)
  Lee Yongho, Isobe Kenichi, Suzuki Haruhiko
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Thymus involution by oral administration of DSS2007
- Author(s)
  SASAKI Makoto, Masataka HANEDA, ISHIDA Yoshiyuki, ISOBE Ken-ichi
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Functional and chemical analysis of a monoclonal antibody that preferentially react with CD8+CD122+ regulatory T cells2007
- Author(s)
  Suzuki Haruhiko, SHI Zhe, LEE Yong Ho, Isobe, ken-ichi, Rifai MuhaiminIsobe
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Deregulated activation of CD4+CD25- cells in the absence of CD8+CD122+ regulatory T cells despite the presence of CD4+CD25+ Treg in vivo2007
- Author(s)
  SHI Zhe, Rifai Muhaimin, LEE Yong Ho, Isobe Ken-ichi、Suzuki Haruhiko
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390191
[Presentation] Murine model of age-related COPD and lung defense system.
- Author(s)
  Sun Y, Ito S, Chen N, Tanaka Y, Liu L, Nishio N, Isobe K.
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] The effects of GADD34 on LPS stimulation in mice.
- Author(s)
  Oshino R, Ito S, Tanaka Y, Nishio N, Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works to　 suppress obesity-induced non alcoholic steatohepatitis (NASH) by regulation of insulin/IGF signaling.
- Author(s)
  Nishio N, Ito S, Isobe K
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] The involvement of growth arrest and DNA damage-inducible protein (GADD34) in the tumorigenesis of hepatocellular carcinoma
- Author(s)
  Chen N, Nishio N, Ito S, Sun Y, Tanaka Y, Isobe K
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Establishment of macrophage stem-like cells from murine yolk sac.
- Author(s)
  Ito S, Oshino R Tanaka Y, Nishio N Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works to suppress obesity-induced metabolic diseases including type 2 diabetes and NASH.
- Author(s)
  Nishio N, Ito S, Isobe K.
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町））
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 promotes colon inflammation and tumorigenesis
- Author(s)
  Tanaka Y Ito S, Oshino R, Nishio N Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Effects of GADD34 to TLR signaling
- Author(s)
  Tanaka Y, Ito S, Oshino R, Nishio N Isobe K.
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166

1. NAKASHIMA Izumi (40022826)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. Nishio Naomi (80513457)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
3. OKADA Hidechika (30160683)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TAKAGI Hiroshi (70154755)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HAYASHI S (30218573)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 大橋憲太郎 (50332953)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 長谷川忠男 (10314014)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. SHIBATA Rei (70343689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. MURO Yoshinao (80270990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. NAKAMURA Jiro (40283444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. KAMIYA Hideki (70542679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. NARUSE Keiko (30387576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. TAKAHASHI Masahide (40183446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KIUCHI Kazutoshi (30135339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHINZATO Toru (00252247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KIMATA Koji (10022641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MAEDA Kenji (90023853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. AKIYAMA Seiji (40202551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KATSURA Yoshimoto (90027095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. FUJIMOTO Shinji (60199370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 岩本隆司 (60223426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 長瀬文彦 (10109340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 鈴木治彦 (90283431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
24. 林登志雄 (80303634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 祖父江元 (20148315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 伊藤佐知子 (70447845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
27. 稲城玲子 (50232509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 藤本豊士 (50115929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TAKEUCHI Akihide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. MORITA Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. TAKESHITA Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. SEKIGUCHI Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 及川信三

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 小林章二

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KOBAYASHI S

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 立野一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
37. 井坂雅徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. 天谷文昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

isobe ken-ichi 磯部 健一

ISOBE Ken-ichi 磯部 健一

磯部 健一 イソベ ケンイチ

ISOBE K 磯部 健一

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Stress responsive GADD34 and metabolic syndromePrincipal Investigator

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Age-related diseases analyzed by ER stresses and immune functions using murine models including iPSCsPrincipal Investigator

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Analysis of tissue failure and treatment by iPSCsPrincipal Investigator

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Host responses to stress and progression to diseasePrincipal Investigator

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ストレス防御系の破綻としての癌発生に関する研究Principal Investigator

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ストレス防御系の破綻としての癌発生に関する研究Principal Investigator

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ERストレス応答におけるGADD34蛋白の役割Principal Investigator

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ストレス防御系の破綻としての癌発生に関する研究Principal Investigator

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ストレス防御系の破綻としての癌発生に関する研究Principal Investigator

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isobe ken-ichi 磯部健一

ISOBE Ken-ichi 磯部健一

磯部健一イソベケンイチ

ISOBE K 磯部健一