SAKAI Toshiyuki 酒井敏行

… Alternative Names

酒井敏行

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Researcher Number	20186993
Other IDs
External Links
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授 2011 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2015: 京都府立医科大学, 医学研究科, 教授 2012: 京都府立医科大学, 大学院・医学研究科, 教授 2003 – 2012: 京都府立医科大学, 医学研究科, 教授 … More 1996 – 2002: KYOTO PREFECTURAL UNIVERSITY,MEDICAL DEPARTMENT,PROFESSOR, 医学部, 教授 1994 – 1995: 京都府立医科大学, 医学部, 助手 1993 – 1995: 京都府立医科大学, 医学部, 講師 1993: 京都府立医科大学, 助手 1992: 京都府立医科大学, 医学部, 助手 1988: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hygiene / Hygiene / Medium-sized Section 58:Society medicine, nursing, and related fields / Hygiene and public health / Biological Sciences / Ophthalmology / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Complex systems / Science and Engineering / Digestive surgery … More Except Principal Investigator … More Basic Section 58020:Hygiene and public health-related: including laboratory approach / Urology / Experimental pathology / 公衆衛生学 / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 38:Agricultural chemistry and related fields / Medium-sized Section 58:Society medicine, nursing, and related fields / Gastroenterology / Plastic surgery / Hygiene / Biological Sciences Less
Keywords	Principal Investigator p53 / gadd45 / TRAIL / ケルセチン / プロモーター / NF-Y / 酪酸 / WAF1 / 癌 / p27 … More / RB / p21 / p15 / DR5 / p18 / TPA / 予防 / 癌抑制遺伝子 / がん予防 / アポトーシス / Oct-1 / promoter / 分子予防 / フラボノイド / 併用 / リ・フラウメニ症候群 / がん / p16 / ゲニステイン / p19 / HDAC阻害剤 / Sp3 / 先制医療 / 天然物 / mac25 / ルテオリン / luciferase / TSA / Vitamin D_3 / フラボン / エピジェネティクス / 食品成分 / 癌予防 / DNAメチル化 / アピゲニン / ビタミンD_3 / 細胞周期 / CCAAT / ヒストン脱アセチル化酵素阻害剤 / 化学予防 / 紫外線 / Δ^<12>-プロスタグランディンJ_2 / gadd45遺伝子 / cancer / Sp1 / butyrate / メチル化 / 網膜芽細胞腫 / ATF / RB遺伝子 / 家族性大腸腺腫症 / がん体質診断 / テーラーメイドがん予防 / アスピリン / 大腸がん / Eomes / T-bet / IL-6 / 細胞老化 / NK細胞 / ケミカルバイオロジー / スクリーニング / SASP / 子宮頸がん / E7 / HPV / 免疫 / タバコ成分 / がん細胞死 / 喫煙 / 抗酸化能 / 飲料 / 抗炎症 / 抗酸化 / RB再活性化 / 分子標的予防法 / I3C / インドール-3-カービノール / quercetin / flavonoids / Sodium Butyrate / ビタミンD_3受容体 / mac25遺伝子 / uv / Vitamin D3 / Oct1 / 遺伝子修復 / UV / 転写因子 / HeLa / UVpromoter / histone deacetylase inhibitor / prevention / リ-フラウメニ症侯群 / SAHA / セストン脱アセチル化酵素阻害剤 / WAP1 / 分子標的予防 / 科学予防 / HDAC阻害 / HDAC阻害作用 / エピジェネテクス / GADD45 / miR-16 / miR-15 / Bcl-2 / miR-222 / miR-221 / miR-34b/c / flavone / G1期停止 / E2F / G1 期停止 / miR-34a / INK4B / INK4A / ヒストンアセチル化 / Crytolepin / MEK阻害剤 / MEK / MAPK / 家族性メラノーマ / p53-RB経路 / テーラーメイド予防 / 発癌促進物質 / 発癌抑制物質 / クルクミン / PKC / CDK / Siah-1 / 環境発癌要因 / 発癌プロモーター / 環境発癌因子 / 転写活性化 / 転写抑制 / 抗癌剤 / telomerase / M期 / G2 / DNA修復 / 網膜芽細胞腫瘍伝子 / 治療 / WAF1遺伝子 / 分化 / 筋細胞 / ATF-1 / G1 phase / Cell cycle / RB gene / p21 gene / 癌体質診断 / 分子生物学 / 家系分析 / 網膜芽細胞腫遺伝子 / Ets / E4TF1 / RBF-1 … More Except Principal Investigator プロモーター / RB / p53 / 網膜芽細胞腫遺伝子 / E4TF1 / RB遺伝子 / 癌抑制遺伝子 / WAF1 / がん予防 / NALP7 / Teratoma / シスプラチン / イリノテカン / アポトーシス / WT1 / 精巣腫瘍 / promoter / tumor suppressor gene / サイレンサー / 分子生物学 / 癌体質診断 / Ets / RBF-1 / ATF / 膵NET / MEN1 / 先制医療 / ヒストン脱アセチル化酵素(HDAC)阻害剤 / 骨肉腫 / 生物間相互作用 / 毒の蓄積 / ヘビの防御物質 / ブファジエノライド / 生物環相互作用 / TRAIL / ヒ素 / 動脈硬化 / 予防 / Monoclonal antibody / Mass screening / gamma-GTP / Pancreatic cancer / γーGTP / α-GTP / 血清診断 / モノクロ-ナル抗体 / γ-GTP / 集団検診 / 膵癌 / cisplatin / irinotecan / retinoblastoma gene / refractory or relapsed GCTs / 胎児性癌 / 分化 / 難治性 / CPT-11 / CDDP / マイクロアレイ / 難治性精巣腫瘍 / Cisplatin / Irinotecan / Chemotherapy / Apoptosis / Induction of Differentiation / Gene / Testicular Tumor / Bnip3L / Apo-2リガンド / p53遺伝子 / p27プロモーター / VD3 / WT1遺伝子 / Embryonal carcinoma / 化学療法 / 分化誘導 / 遺伝子 / PROMOTER / Cip1 / G1 ARREST / BUTYRATE / COLON CANCER / G1期停止 / 遺伝子プロモーター / WAF1遺伝子 / G_1期停止 / 酪酸 / 大腸癌 / enhancer / peptide library / 転写調節 / エンハンサー / ペプチドライブラリー / ＰＢＭＣ / ＩＬ－６ / ケロイド線維芽細胞 / HDAC阻害剤 / MEK阻害剤 / コラーゲン / 線維芽細胞 / ケロイド / ヘリコバクター・ピロリ / CDK2活性 / 細胞周期プロファイリング / 転写活性化 / 転写抑制 / 抗癌剤 / 細胞周期 / Sp3 / p21 / ヒストン脱アセチル化酵素阻害剤 / EBウイルス / 自殺遺伝子 / 遺伝子治療 / E2F / メチル化 / 公衆衛生学 Less

遺伝性乳がん卵巣がん症候群に対する先制医療の開発Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel molecular target combination therapy for osteosarcoma
- Principal Investigator
  
  村田博昭
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of preemptive medical care for pre-symptomatic MEN1 gene mutation carriers
- Principal Investigator
  
  堀中真野
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Development of preemptive medicine against RB-mutated malignanciesPrincipal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Bufadienolides, a snake defense substance: Investigation of the mechanism of dietary evolution.
- Principal Investigator
  
  森直樹
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Kyoto University
Basic research for prevention of arteriosclerosis by cancer preventive ingredients with RB activation ability
- Principal Investigator
  
  Tomosugi (Horinaka) Mano
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Tailor-maid cancer prevention towards the era of preemptive medicine.Principal Investigator
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Preventive strategy against arsenic carcinogenesis by TRAIL pathway activation and RB activation
- Principal Investigator
  
  Horinaka Mano
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
A new colorectal cancer chemoprevention method to reduce side effects of aspirinPrincipal Investigator
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Research of molecular-targeting prevention against inflammatory diseases using chemical biology.Principal Investigator
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular-targeting prevention against human papilloma virus-positive cervical cancerPrincipal Investigator
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Application of molecular-targeting cancer prevention to human intervention study.Principal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the novel mechanisms of carcinogenesis induced by the cigarette and development of cancer prevention for carcinogenesis by sidestream smokePrincipal Investigator
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Novel combination-oriented molecular-targeting therapy for keloid
- Principal Investigator
  
  Nishino Kenichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Novel molecular-targeting prevention of cancer by sensitizing the effect of sodium butyratePrincipal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of micrRNA-targeting cancer preventionPrincipal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
GADD45を標的とした新規癌予防エピジェネティクスPrincipal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
TRAILとDR5を標的とした癌の「分子標的併用療法」の開発Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
エピジェネティックに失活した癌抑制遺伝子を標的とした新規癌予防法の開発Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
癌抑制遺伝子群の発現を調節する癌治療薬シーズの探索Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto Prefectural University of Medicine
ヒト環境発癌分子を標的とした新規発癌抑制物質スクリーニング系の構築Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Research on a selection reference of chemopreventive agents for cancer and a development of tailor-made medicine for cancer preventionPrincipal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
新規細胞周期プロファイリング装置を用いた胃前癌病変のリスク診断と癌予防への応用
- Principal Investigator
  
  神山順
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Meiji College of Oriental Medicine
癌の「分子標的予防法」の開発に関する基礎的研究Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
種々の環境発癌因子の標的分子の同定―「分子標的予防法」に向けての基礎的研究Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Basic research for ‘gene-regulating chemoprevention' by using food factorsPrincipal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of tumor suppressor gene in refractory or relapsed germ cell tumors and its therapeutic application
- Principal Investigator
  
  MIKI Tsuneharu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kyoto Prefectural University of Medicine
ヒストン脱アセチル化酵素阻害剤によるP21/WAF1遺伝子誘導機構の解析
- Principal Investigator
  
  SOWA Yoshihiro
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
大腸癌に対するヒストン脱アセチル化酵素阻害剤の抗腫瘍効果の作用機構の解析Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development of the new cancer preventing method with the ingredient of the food of KyotoPrincipal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Study on gene analysis and gene expresssion associated with differentiation in testicular germ cell tumor
- Principal Investigator
  
  MIKI Tsuneharu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Urology
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
Development of specific prevention against DNA damage caused by environmentPrincipal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of specific prevention against people with high susceptibility for cancer and general carcinogenesisPrincipal Investigator
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
腫瘍細胞特異的に外来遺伝子を発現させる新しい遺伝子導入システムの開発
- Principal Investigator
  
  佐藤悦子
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto Prefectural University of Medicine
DNA修復遺伝子gadd45の誘導物質の検索-新しい化学予防物質の検索法の確立に向けて-Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
網膜芽細胞腫に対する新しい治療法及び予防法の基礎的研究Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
STUDY ON NEW THERAPY FOR COLON CANCER
- Principal Investigator
  
  MATSUKAWA Yoshizumi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
網膜芽細胞腫遺伝子プロモーター領域における調節機構
- Principal Investigator
  
  川井啓市
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Prefectural University of Medicine
網膜芽細胞腫遺伝子プロモーター領域における調節機構
- Principal Investigator
  
  川井啓市
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto Prefectural University of Medicine
Detection of novel molecules that regulates RB expression by screening random peptide library
- Principal Investigator
  
  TAKAHASHI Rei
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  KYOTO UNIVERSITY
公衆衛生学的に有用な新しい癌体質診断法の開発
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  公衆衛生学
- Research Institution
  Kyoto Prefectural University of Medicine
網膜芽細胞腫の家系分析における新手法の開発Principal Investigator
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Development of serological diagnosis of pancreatic cancer for mass screening
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  公衆衛生学
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] ＴＨＥ創薬 -少資源国家にっぽんの生きる道-2021
- Author(s)
  酒井敏行
- Publisher
  薬事日報社
- ISBN
  9784840815536
- Data Source
  KAKENHI-PLANNED-17H06398
[Book] THE創薬-少資源国家にっぽんの生きる道-2021
- Author(s)
  酒井敏行
- Publisher
  薬事日報社
- Data Source
  KAKENHI-PROJECT-19H01079
[Book] Precision Medicine　2020年4月号2020
- Author(s)
  小野寿子、酒井敏行
- Total Pages
  4
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-19H01079
[Book] Precision Medicine　2020年4月号2020
- Author(s)
  小野寿子、酒井敏行
- Total Pages
  4
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Design, synthesis, and biological evaluation of phenylcyclopropylamine-entinostat conjugates that selectively target cancer cells2024
- Author(s)
  Ota Y, Itoh Y, Takada Y, Yamashita Y, Hu C, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 100 Pages: 117632-117632
- DOI
  10.1016/j.bmc.2024.117632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795
[Journal Article] Effects of combined therapeutic targeting of AXL and ATR on pleural mesothelioma cells2024
- Author(s)
  Hirai S, Yamada T, Katayama Y, Ishida M, Kawachi H, Matsui Y, Nakamura R, Morimoto K, Horinaka M, Sakai T, Sekido Y, Tokuda S, Takayama K
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 23 Issue: 2 Pages: 212-222
- DOI
  10.1158/1535-7163.mct-23-0138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-23K07607, KAKENHI-PROJECT-21K15513, KAKENHI-PROJECT-19H01079
[Journal Article] Identification of c-Met as a novel target of γ-glutamylcyclotransferase2023
- Author(s)
  Saito Y, Taniguchi K, Ii H, Horinaka M, Kageyama S, Nakata S, Ukimura O, Sakai T
- Journal Title
  
  Sci Rep
  
  Volume: 13 Issue: 1 Pages: 11922-11922
- DOI
  10.1038/s41598-023-39093-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-22K17350, KAKENHI-PROJECT-22K06756, KAKENHI-PROJECT-23K06642, KAKENHI-PROJECT-21K09342, KAKENHI-PROJECT-19H01079
[Journal Article] Discovery of cancer-preventive juices reactivating RB functions2023
- Author(s)
  Masuda M, Horinaka M, Yasuda S, Morita M, Nishimoto E, Ishikawa H, Mutoh M, Sakai T
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 28 Issue: 0 Pages: 54-54
- DOI
  10.1265/ehpm.23-00160
- ISSN
  1342-078X, 1347-4715
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-23K27841
[Journal Article] Adaptive resistance to lorlatinib via EGFR signaling in ALK-rearranged lung cancer2023
- Author(s)
  Katayama Y, Yamada T, Tanimura K, Tokuda S, Morimoto K, Hirai S, Matsui Y, Nakamura R, Ishida M, Kawachi H, Yoneda K, Hosoya K, Tsuji T, Ozasa H, Yoshimura A, Iwasaku M, Kim YH, Horinaka M, Sakai T, Utsumi T, Shiotsu S, Takeda T, Katayama R, Takayama K
- Journal Title
  
  npj Precision Oncology
  
  Volume: 7 Issue: 1 Pages: 12-12
- DOI
  10.1038/s41698-023-00350-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-22K18383
[Journal Article] Discovery of selective histone deacetylase 1 and 2 inhibitors: screening of a focused library constructed by click chemistry, kinetic binding analysis, and biological evaluation2023
- Author(s)
  Itoh Y, Zhan P, Tojo T, Jaikhan P, Ota Y, Suzuki M, Li Y, Hui Z, Moriyama Y, Takada Y, Yamashita Y, Oba M, Uchida S, Masuda M, Ito S, Sowa Y, Sakai T, Suzuki T
- Journal Title
  
  J Med Chem
  
  Volume: 66 Issue: 22 Pages: 15171-15188
- DOI
  10.1021/acs.jmedchem.3c01095
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-20K15959, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-23K23487
[Journal Article] Development of an activity-based chemiluminogenic probe for γ-glutamylcyclotransferase2023
- Author(s)
  Nohara Y, Taniguchi K, Ii H, Masuda S, Kawakami H, Matsumoto M, Hattori Y, Kageyama S, Sakai T, Nakata S, Yoshiya T
- Journal Title
  
  Org Biomol Chem
  
  Volume: 21 Issue: 29 Pages: 5977-5984
- DOI
  10.1039/d3ob00655g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-22K17350, KAKENHI-PROJECT-22K06756, KAKENHI-PROJECT-23K06642, KAKENHI-PROJECT-21K09342, KAKENHI-PROJECT-19H01079
[Journal Article] The Rationale for the Dual-Targeting Therapy for RSK2 and AKT in Multiple Myeloma.2022
- Author(s)
  Isa R, Horinaka M, Tsukamoto T, Mizuhara K, Fujibayashi Y, Taminishi-Katsuragawa Y, Okamoto H, Yasuda S, Kawaji-Kanayama Y, Matsumura-Kimoto Y, Mizutani S, Shimura Y, Taniwaki M, Sakai T, Kuroda J.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23 Issue: 6 Pages: 2919-2936
- DOI
  10.3390/ijms23062919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08872, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-21K16246, KAKENHI-PROJECT-21K16274
[Journal Article] Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthinol2022
- Author(s)
  Iizumi Yosuke, Sowa Yoshihiro, Goi Wakana, Aono Yuichi, Watanabe Motoki, Kurumida Yoichi, Kameda Tomoshi, Akaji Kenichi, Kitagawa Masatoshi, Sakai Toshiyuki.
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 564-564
- DOI
  10.1038/s42003-022-03522-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-22K10489, KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079
[Journal Article] Heterogeneity among tumors with acquired resistance to EGFR tyrosine kinase inhibitors harboring EGFR-T790M mutation in non-small cell lung cancer cells2022
- Author(s)
  Katayama Y, Yamada T, Tokuda S, Okura N, Nishioka N, Morimoto K, Tanimura K, Morimoto Y, Iwasaku M, Horinaka M, Sakai T, Kita K, Yano S, Takayama K
- Journal Title
  
  Cancer Medicine
  
  Volume: 11 Issue: 4 Pages: 944-955
- DOI
  10.1002/cam4.4504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-21K15513
[Journal Article] A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS52022
- Author(s)
  Watanabe M, Boku S, Kobayashi K, Kurumida Y, Sukeno M, Masuda M, Mizushima K, Kato C, Iizumi Y, Hirota K, Naito Y, Mutoh M, Kameda T, Sakai T
- Journal Title
  
  PNAS Nexus
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand is a novel transcriptional target of runt-related transcription factor 12022
- Author(s)
  Yoshida Tatsushi、Yamasaki Kenta、Tadagaki Kenjiro、Kuwahara Yasumichi、Matsumoto Akifumi、Sofovic Adem、Kondo Noriko、Sakai Toshiyuki、Okuda Tsukasa
- Journal Title
  
  International Journal of Oncology
  
  Volume: 60 Issue: 1 Pages: 1-1
- DOI
  10.3892/ijo.2021.5296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS52022
- Author(s)
  Watanabe Motoki、Boku Shogen、Kobayashi Kaito、Kurumida Yoichi、Sukeno Mamiko、Masuda Mitsuharu、Mizushima Katsura、Kato Chikage、Iizumi Yosuke、Hirota Kiichi、Naito Yuji、Mutoh Michihiro、Kameda Tomoshi、Sakai Toshiyuki
- Journal Title
  
  PNAS Nexus
  
  Volume: 1 Issue: 2
- DOI
  10.1093/pnasnexus/pgac059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10489, KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079
[Journal Article] Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthinol2022
- Author(s)
  Iizumi Y, Sowa Y, Goi W, Aono Y, Watanabe M, Kurumida Y, Kameda T, Akaji K, Kitagawa M, Sakai T.
- Journal Title
  
  Communications Biology
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS52022
- Author(s)
  Watanabe M, Boku S, Kobayashi K, Kurumida Y, Sukeno M, Masuda M, Mizushima K, Kato C, Iizumi Y, Hirota K, Naito Y, Mutoh M, Kameda T, Sakai T
- Journal Title
  
  PNAS Nexus
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01079
[Journal Article] HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal features.2022
- Author(s)
  Tanimura K, Yamada T, Okada K, Nakai K, Horinaka M, Katayama Y, Morimoto K, Ogura Y, Takeda T, Shiotsu S, Ichikawa K, Watanabe S, Morimoto Y, Iwasaku M, Kaneko Y, Uchino J, Taniguchi H, Yoneda K, Matoba S, Sakai T, Uehara H, Yano S, Kusaba T, Katayama R, Takayama K.
- Journal Title
  
  NPJ Precis Oncol.
  
  Volume: 6 Issue: 1 Pages: 5-5
- DOI
  10.1038/s41698-021-00250-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08608, KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-20K22820, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20K08640
[Journal Article] “RB-reactivator screening” as a novel cell-based assay for discoveries of molecular targeting agents including the first-in-class MEK inhibitor trametinib (trade name: Mekinist)2022
- Author(s)
  Sakai T
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 236 Pages: 108234-108234
- DOI
  10.1016/j.pharmthera.2022.108234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079
[Journal Article] Citrus limon L.-Derived Nanovesicles Show an Inhibitory Effect on Cell Growth in p53-Inactivated Colorectal Cancer Cells via the Macropinocytosis Pathway2022
- Author(s)
  Takakura Hideki、Nakao Toshimasa、Narita Takumi、Horinaka Mano、Nakao-Ise Yukako、Yamamoto Tetsushi、Iizumi Yosuke、Watanabe Motoki、Sowa Yoshihiro、Oda Keisuke、Mori Nobuhiro、Sakai Toshiyuki、Mutoh Michihiro
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 6 Pages: 1352-1352
- DOI
  10.3390/biomedicines10061352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10489, KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Cancer-cell-selective targeting by arylcyclopropylamine-vorinostat conjugates2022
- Author(s)
  Ota Y, Itoh Y, Kurohara T, Singh R, Elboray EE, Hu C, Zamani F, Mukherjee A, Takada Y, Yamashita Y, Morita M, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 13 Issue: 10 Pages: 1568-1573
- DOI
  10.1021/acsmedchemlett.2c00126
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-21K15226, KAKENHI-PROJECT-22K15251, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21H04795, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20F40107, KAKENHI-PROJECT-21K20719
[Journal Article] Oridonin inhibits SASP by blocking p38 and NF-κB pathways in senescent cells2022
- Author(s)
  Yasuda Shusuke、Horinaka Mano、Iizumi Yosuke、Goi Wakana、Sukeno Mamiko、Sakai Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 55-62
- DOI
  10.1016/j.bbrc.2021.12.098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Salicylic acid directly binds to ribosomal protein S3 and suppresses CDK4 expression in colorectal cancer cells2022
- Author(s)
  Imai A, Horinaka M, Aono Y, Iizumi Y, Takakura H, Ono H, Yasuda S, Taniguchi K, Nishimoto E, Ishikawa H, Mutoh M, Sakai T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 628 Pages: 110-115
- DOI
  10.1016/j.bbrc.2022.08.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-22K17350, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients2022
- Author(s)
  Mure Kanae、Ishikawa Hideki、Mutoh Michihiro、Horinaka Mano、Otani Takahiro et al.
- Journal Title
  
  Cancer Research Communications
  
  Volume: 2 Issue: 6 Pages: 483-488
- DOI
  10.1158/2767-9764.crc-22-0088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11791, KAKENHI-PROJECT-22K18407, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells2022
- Author(s)
  Takakura H, Horinaka M, Imai A, Aono Y, Nakao T, Miyamoto S, Iizumi Y, Watanabe M, Narita T, Ishikawa H, Mutoh M, Sakai T
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 2 Pages: 93-102
- DOI
  10.3164/jcbn.21-74
- NAID
  130008165971
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Inhibition of c-Jun N-terminal kinase signaling increased apoptosis and prevented the emergence of ALK-TKI-tolerant cells in ALK-rearranged non-small cell lung cancer.2021
- Author(s)
  Tanimura K, Yamada T, Horinaka M, Katayama Y, Fukui S, Morimoto K, Nakano T, Tokuda S, Morimoto Y, Iwasaku M, Kaneko Y, Uchino J, Yoneda K, Yano S, Sakai T, Takayama K.
- Journal Title
  
  Cancer Lett.
  
  Volume: 522 Pages: 119-128
- DOI
  10.1016/j.canlet.2021.09.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08608, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Rabdosianone I, a Bitter Diterpene from an Oriental Herb, Suppresses Thymidylate Synthase Expression by Directly Binding to ANT2 and PHB22021
- Author(s)
  Watanabe M, Yamada Y, Kurumida Y, Kameda T, Sukeno M, Iizuka-Ohashi M, Sowa Y, Iizumi Y, Takakura H, Miyamoto S, Sakai T, Mutoh M.
- Journal Title
  
  Cancers.
  
  Volume: 13 Issue: 5 Pages: 982-982
- DOI
  10.3390/cancers13050982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] The combination of cigarette smoking and alcohol consumption synergistically increases reactive carbonyl species in human male plasma2021
- Author(s)
  Mure K, Tomono S, Mure M, Horinaka M, Mutoh M, Sakai T, Ishikawa H, Wakabayashi K
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 16 Pages: 9043-9043
- DOI
  10.3390/ijms22169043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20K11635, KAKENHI-PROJECT-21K18291, KAKENHI-PROJECT-18H03054
[Journal Article] Novel RAF/MEK inhibitor CH5126766/VS‐6766 has efficacy in combination with eribulin for the treatment of triple‐negative breast cancer2021
- Author(s)
  Ono H, Horinaka M, Sukeno M, Morita M, Yasuda S, Nishimoto E, Konishi E, Sakai T
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 10 Pages: 4166-4175
- DOI
  10.1111/cas.15071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-20K18906
[Journal Article] γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis2021
- Author(s)
  Taniguchi Keiko、Kageyama Susumu、Moyama Chiami、Ando Shota、Ii Hiromi、Ashihara Eishi、Horinaka Mano、Sakai Toshiyuki、Kubota Shigehisa、Kawauchi Akihiro、Nakata Susumu
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: - Issue: 1 Pages: 37-48
- DOI
  10.1038/s41417-020-00287-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07623, KAKENHI-PROJECT-20K23233, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-19K22773, KAKENHI-PROJECT-21K09342
[Journal Article] Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial2021
- Author(s)
  Ishikawa H、Mutoh M、Sato Y、Doyama H、Tajika M、Tanaka S、Horimatsu T、Takeuchi Y、Kashida H、Tashiro J、Ezoe Y、Nakajima T、Ikematsu H、Hori S、Suzuki S、Otani T、Takayama T、Ohda Y、Mure K、Wakabayashi K、Sakai T
- Journal Title
  
  The Lancet Gastroenterology & Hepatology
  
  Volume: － Issue: 6 Pages: 474-481
- DOI
  10.1016/s2468-1253(21)00018-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03054, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-21K11791
[Journal Article] The HDAC inhibitor OBP-801 suppresses the growth of myxofibrosarcoma cells.2020
- Author(s)
  Kawarazaki A, Horinaka M, Yasuda S, Kawashima H, Numajiri T, Sakai T.
- Journal Title
  
  J BUON
  
  Volume: 25 Pages: 464-471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03889
[Journal Article] The HDAC inhibitor OBP-801 suppresses the growth of myxofibrosarcoma cells.2020
- Author(s)
  Kawarazaki A, Horinaka M, Yasuda S, Kawashima H, Numajiri T, Sakai T.
- Journal Title
  
  J BUON.
  
  Volume: 25 Pages: 464-471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of NOXA.2020
- Author(s)
  Sugimoto Y, Katsumi Y, Iehara T, Kaneda D, Tomoyasu C, Ouchi K, Yoshida H, Miyachi M, Yagyu S, Kikuchi K, Tsuchiya K, Kuwahara Y, Sakai T, Hosoi H.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 19 Issue: 10 Pages: 1992-2000
- DOI
  10.1158/1535-7163.mct-20-0243
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] The HDAC inhibitor OBP-801 suppresses the growth of myxofibrosarcoma cells.2020
- Author(s)
  Kawarazaki A, Horinaka M, Yasuda S, Kawashima H, Numajiri T, Sakai T.
- Journal Title
  
  J BUON.
  
  Volume: 25 Pages: 464-471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01079
[Journal Article] Histone deacetylase inhibitor OBP-801 and amrubicin synergistically inhibit the growth of squamous cell lung carcinoma by inducing mitochondrial ASK1-dependent apoptosis.2020
- Author(s)
  Chihara Y, Iizumi Y, Horinaka M, Watanabe M, Goi W, Morita M, Nishimoto E, Sowa Y, Yamada T, Takayama K, Sakai T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 56 Pages: 848-856
- DOI
  10.3892/ijo.2020.4969
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-19K22773
[Journal Article] Artesunate Inhibits Intestinal Tumorigenesis through Inhibiting Wnt Signaling.2020
- Author(s)
  Hamoya T, Fujii G, Iizumi Y, Narita T, Komiya M, Matsuzawa Y, Miki K, Kondo T, Kishimoto S, Watanabe K, Wakabayashi K, Sakai T, Toshima J, Mutoh M
- Journal Title
  
  Carcinogenesis
  
  Volume: 42 Issue: 1 Pages: 148-58
- DOI
  10.1093/carcin/bgaa084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11066, KAKENHI-PROJECT-19K06571, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H02898, KAKENHI-PROJECT-19J10184
[Journal Article] ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in EGFR-Mutated Non?Small Cell Lung Cancer2020
- Author(s)
  Okura N, Nishioka N, Yamada T, Taniguchi H, Tanimura K, Katayama Y, Yoshimura A, Watanabe S, Kikuchi T, Shiotsu S, Kitazaki T, Nishiyama A, Iwasaku M, Kaneko Y, Uchino J, Uehara H, Horinaka M, Sakai T, Tanaka K, Kozaki R, Yano S, Takayama K.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 26 Issue: 9 Pages: 2244-2256
- DOI
  10.1158/1078-0432.ccr-19-2321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0019, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19K08608, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-23K20323
[Journal Article] Very long-term treatment with a Lactobacillus probiotic preparation, Lactobacillus Casei strain Shirota, suppresses weight loss in the elderly.2020
- Author(s)
  Ishikawa H, Mutoh M, Yoshimura K, Fujii G, Nakamura T, Takeshita T, Wakabayashi K, Sakai T.
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 6 Pages: 1599-1599
- DOI
  10.3390/nu12061599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11066, KAKENHI-PROJECT-19K10581, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-19K22773
[Journal Article] Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression.2020
- Author(s)
  Umemura S, Sowa Y, Iizumi Y, Kitawaki J, Sakai T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 6 Pages: 2052-2061
- DOI
  10.1111/cas.14414
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-18K09295
[Journal Article] Deactivation of Glutaminolysis Sensitizes PIK3CA-Mutated Colorectal Cancer Cells to Aspirin-Induced Growth Inhibition.2020
- Author(s)
  Boku S, Watanabe M, Sukeno M, Yaoi T, Hirota K, Iizuka-Ohashi M, Itoh K, Sakai T.
- Journal Title
  
  Cancers (Basel).
  
  Volume: 12 Issue: 5 Pages: 1097-1097
- DOI
  10.3390/cancers12051097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23179, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-18K08874, KAKENHI-PROJECT-18K19693
[Journal Article] Cycloartenyl Ferulate and β-Sitosteryl Ferulate - Steryl Ferulates of γ-Oryzanol - Suppress Intracellular Reactive Oxygen Species in Cell-based System2019
- Author(s)
  Yasuda S, Sowa Y, Hashimoto H, Nakagami T, Tsuno T, Sakai T.
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 68 Issue: 8 Pages: 765-768
- DOI
  10.5650/jos.ess19054
- NAID
  130007686318
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] Sulforaphane enhances apoptosis induced by Lactobacillus pentosus strain S-PT84 via the TNFα pathway in human colon cancer cells.2019
- Author(s)
  Yasuda S, Horinaka M, Sakai T.
- Journal Title
  
  Oncol Lett.
  
  Volume: 18 Pages: 4253-4261
- DOI
  10.3892/ol.2019.10739
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Effect of physical fitness on colorectal tumor development in patients with familial adenomatous polyposis2019
- Author(s)
  Nakamura T, Ishikawa H, Sakai T, Ayabe M, Wakabayashi K, Mutoh M, Matsuura N.
- Journal Title
  
  Medicine
  
  Volume: 98 Issue: 38 Pages: e17076-e17076
- DOI
  10.1097/md.0000000000017076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] Utility of mesalazine in familial adenomatous polyposis: clinical report of reduction of polyp size in patients with ulcerative colitis, and safety examination in familial adenomatous polyposis patients.2019
- Author(s)
  Ishikawa H, Mutoh M, Abe T, Nakajima T, Takeuchi Y, Ezoe Y, Wakabayashi K, Doyama H, Sakai T.
- Journal Title
  
  Pharmacology
  
  Volume: 104 Issue: 1-2 Pages: 51-56
- DOI
  10.1159/000500226
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] Cycloartenyl ferulate and β-sitosteryl ferulate, steryl ferulates of γ-oryzanol, suppressed intracellular reactive oxygen species in the cell-based system.2019
- Author(s)
  Yasuda S, Sowa Y, Hashimoto H, Nakagami T, Tsuno T, Sakai T.
- Journal Title
  
  Journal of Oleo Science
  
  Volume: 印刷中
- NAID
  130007686318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02529
[Journal Article] Mutations in the RAS pathway as potential precision medicine targets in treatment of rhabdomyosarcoma.2019
- Author(s)
  Nakagawa N, Kikuchi K, Yagyu S, Miyachi M, Iehara T, Tajiri T, Sakai T, Hosoi H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 512 Issue: 3 Pages: 524-530
- DOI
  10.1016/j.bbrc.2019.03.038
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10123, KAKENHI-PROJECT-17H04230, KAKENHI-PROJECT-19K09053, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03719, KAKENHI-PROJECT-17K11517, KAKENHI-PROJECT-17K11518
[Journal Article] Mevalonate pathway blockage enhances the efficacy of mTOR inhibitors with the activation of retinoblastoma protein in renal cell carcinoma2018
- Author(s)
  Hagiwara Nobuhisa、Watanabe Motoki、Iizuka-Ohashi Mahiro、Yokota Isao、Toriyama Seijiro、Sukeno Mamiko、Tomosugi Mitsuhiro、Sowa Yoshihiro、Hongo Fumiya、Mikami Kazuya、Soh Jintetsu、Fujito Akira、Miyashita Hiroaki、Morioka Yukako、Miki Tsuneharu、Ukimura Osamu、Sakai Toshiyuki
- Journal Title
  
  Cancer Letters
  
  Volume: 431 Pages: 182-189
- DOI
  10.1016/j.canlet.2018.05.025
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398
[Journal Article] Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells.2018
- Author(s)
  Iizuka-Ohashi M1,2, Watanabe M1, Sukeno M1, Morita M1, Hoang NTH3, Kuchimaru T, Kizaka-Kondoh S, Sowa Y1 Sakaguchi K, Taguchi T, Sakai T.
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 28 Pages: 19597-19612
- DOI
  10.18632/oncotarget.24696
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10512, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-16K15378
[Journal Article] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 22018
- Author(s)
  Aono Yuichi、Horinaka Mano、Iizumi Yosuke、Watanabe Motoki、Taniguchi Tomoyuki、Yasuda Shusuke、Sakai Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Issue: 4 Pages: 1203-1210
- DOI
  10.1016/j.bbrc.2018.10.050
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-16H05260, KAKENHI-PROJECT-17K19829
[Journal Article] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2.2018
- Author(s)
  Aono Y, Horinaka M, Iizumi Y, Watanabe M, Taniguchi T, Yasuda S, Sakai T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Pages: 1203-1210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02529
[Journal Article] Ribosomal protein S3 regulates XIAP expression independently of the NF-κB pathway in breast cancer cells2017
- Author(s)
  Ono H, Iizumi Y, Goi W, Sowa Y, Taguchi T, Sakai T
- Journal Title
  
  Oncol Rep
  
  Volume: 38 Issue: 5 Pages: 3205-3210
- DOI
  10.3892/or.2017.6008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Apigenin sensitizes prostate cancer cells to Apo2L/TRAIL by targeting adenine nucleotide translocase-22013
- Author(s)
  Oishi M, Iizumi Y, Taniguchi T, Goi W, Miki T, Sakai T
- Journal Title
  
  PLoS One
  
  Volume: Vol. 8、 No. 2 Issue: 2 Pages: e55922-e55922
- DOI
  10.1371/journal.pone.0055922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23659335, KAKENHI-PROJECT-23689036
[Journal Article] Clostridium butyricum MIYAIRI 588 shows antitumor effects by enhancing the release of TRAIL from neutrophils through MMP-8.2013
- Author(s)
  Masahide Shinnoh, Mano Horinaka, Takashi Yasuda, Sae Yoshikawa, Mie Morita, Takeshi Yamada, Tsuneharu Miki, Toshiyuki Sakai
- Journal Title
  
  International Journal of Oncology
  
  Volume: 42 Issue: 3 Pages: 903-911
- DOI
  10.3892/ijo.2013.1790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-24659304
[Journal Article] Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT -29 human colon cancer cells2013
- Author(s)
  Yogosawa S, Yamada Y, Yasuda S, Sun Q, Takizawa K, Sakai T
- Journal Title
  
  J Nat Prod
  
  Volume: Vol. 75、 No. 12 Issue: 12 Pages: 2088-2093
- DOI
  10.1021/np300465f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790669
[Journal Article] Perillyl alcohol causes G1 arrest through p15INK4band p21WAF1/Cip1induction2013
- Author(s)
  Koyama M, Sowa Y, Hitomi T, Iizumi Y, Watanabe M, Taniguchi T, Ichikawa M, Sakai T
- Journal Title
  
  Oncol Rep
  
  Volume: Vol. 29、 No. 2 Issue: 2 Pages: 779-784
- DOI
  10.3892/or.2012.2167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23590741, KAKENHI-PROJECT-23689036
[Journal Article] Retinoblastoma gene-independent G1 phase arrest by flavone, phosphatidylinositol 3-kinase inhibitor, and histone deacetylase inhibitor2012
- Author(s)
  Tomosugi M, Sowa Y, Yasuda S, Tanaka R, te Riele H, Ikawa H, Koyama M, Sakai T
- Journal Title
  
  Cancer Sci.
  
  Volume: Vol. 103、 No. 12 Issue: 12 Pages: 2139-2143
- DOI
  10.1111/cas.12012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790670, KAKENHI-PROJECT-24591958
[Journal Article] Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells2012
- Author(s)
  Izutani Y, Yogosawa S, Sowa Y, Sakai T
- Journal Title
  
  Int J Oncol
  
  Volume: Vol. 40、 No. 3 Pages: 816-824
- DOI
  10.3892/ijo.2011.1246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790669
[Journal Article] The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells.2012
- Author(s)
  Jun Fujiwara, Yoshihiro Sowa, Mano Horinaka, Makoto Koyama, Miki Wakada, Tsuneharu Miki, Toshiyuki Sakai
- Journal Title
  
  International Journal of Oncology
  
  Volume: 40 Pages: 1483-1491
- DOI
  10.3892/ijo.2012.1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-24591958
[Journal Article] Aclarubicin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis through death receptor 5 upregulation.2012
- Author(s)
  Mano Horinaka, Tatsushi Yoshida, Susumu Nakata, Takumi Shiraishi, Mitsuhiro Tomosugi, Sae Yoshikawa, Miki Wakada, Toshiyuki Sakai
- Journal Title
  
  Cancer Science
  
  Volume: 103 Issue: 2 Pages: 282-287
- DOI
  10.1111/j.1349-7006.2011.02150.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-23791491
[Journal Article] Targeting the glyoxalase pathway enhances TRAIL efficacy in cancer cells by downregulating the expression of antiapoptotic molecules.2012
- Author(s)
  Hiroya Taniguchi, Mano Horinaka, Tatsushi Yoshida, Kimihiro Yano, Ahmed E Goda, Shusuke Yasuda, Miki Wakada, Toshiyuki Sakai
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 11 Pages: 2294-2300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336
[Journal Article] Targeting the glyoxalase pathway enhances TRAIL efficacy in cancer cells by downregulating the expression of antiapoptotic molecules2012
- Author(s)
  Hiroya Taniguchi, Mano Horinaka, Tatsushi Yoshida, Kimihiro Yano, Ahmed E Goda, Shusuke Yasuda, Miki Wakada, Toshiyuki Sakai.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 11 Pages: 2294-2294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336
[Journal Article] Chetomin induces degradation of XIAP and enhances TRAIL sensitivity in urogenital cancer cells.2011
- Author(s)
  Yano K, Horinaka M, Yoshida T, Yasuda T, Taniguchi H, Goda AE, Wakada M, Yoshikawa S, Nakamura T, Kawauchi A, Miki T, Sakai T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 38 Pages: 365-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Inhibition of tissue transglutaminase sensitizes TRAIL-resistant lung cancer cells through upregulation of death receptor 5.2010
- Author(s)
  Frese-Schaper M, Schardt JA, Sakai T, Carboni GL, Schmid RA, Frese S.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 2867-2871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Polymorphisms in promoter sequences of the p15^<INK4B> and PTEN genes of normal Japanese individuals.2010
- Author(s)
  Ohsaka Y, Yogosawa S, Nakanishi R, Sakai T, Nishino H.
- Journal Title
  
  Biochem Genet.
  
  Volume: 48 Pages: 970-986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Histone deacetylase inhibitors and 15-deoxy-Δ^<12,14>-Prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 16 Pages: 2320-2332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells.2010
- Author(s)
  Horinaka M, Yoshida T, Kishi A, Akatani K, Yasuda T, Kouhara J, Wakada M, Sakai T.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 577-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells2010
- Author(s)
  Horinaka M, Yoshida T, Kishi A, Akatani K, Yasuda T, Kouhara J, Wakada M, Sakai T
- Journal Title
  
  FEBS Lett
  
  Volume: Vol. 584、 No. 3 Issue: 3 Pages: 577-82
- DOI
  10.1016/j.febslet.2009.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042
[Journal Article] Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells.2010
- Author(s)
  Yasuda S, Yogosawa S, Izutani Y, Nakamura Y, Watanabe H, Sakai T.
- Journal Title
  
  Mol Nutr Food Res.
  
  Volume: 54 Pages: 559-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] A novel MEK1/2 inhibitor induces G1/S cell cycle arrest in human fibrosarcoma cells.2010
- Author(s)
  Matsui TA, Murata H, Sowa Y, Sakabe T, Koto K, Horie N, Tsuji Y, Sakai T, Kubo T.
- Journal Title
  
  Oncol Rep.
  
  Volume: 24 Pages: 329-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell leukemia Jurkat cells.2010
- Author(s)
  Uchiyama H, Sowa Y, Wakada M, Yogosawa M, Nakanishi R, Horinaka M, Shimazaki C, Taniwaki M, Sakai T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Pages: 728-734
- NAID
  10026589738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Histone deacetylase inhibitors and 15-deoxy-△^<12,14>-prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Journal Title
  
  Clin Cancer Res. 16
  
  Pages: 2320-2332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells2010
- Author(s)
  Yasuda S, Yogosawa S, Izutani Y, Nakamura Y, Watanabe H, Sakai T
- Journal Title
  
  Mol Nutr Food Res
  
  Volume: Vol. 54、 No. 4 Issue: 4 Pages: 559-565
- DOI
  10.1002/mnfr.200900165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042
[Journal Article] Histone deacetylase inhibitors and 15-deoxy-・12,14-prostaglandin J2 synergistically induce apoptosis2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T
- Journal Title
  
  Clin Cancer Res.
  
  Volume: Vol. 16、No. 8 Issue: 8 Pages: 2320-2332
- DOI
  10.1158/1078-0432.ccr-09-2301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042
[Journal Article] Death receptor 5 targeting activity-guided isolation of isoflavones from Millettia brandisiana and Ardisia colorata and evaluation of ability to induce TRAIL-mediated apoptosis2009
- Author(s)
  Kikuchi H, Sakai T(他4名)
- Journal Title
  
  Bioorg Med Chem 17
  
  Pages: 1181-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Nitric oxide sensitizes tumor cells to TRAIL-induced apoptosis via inhibition of the DR5 transcription repressor Yin Yang 12009
- Author(s)
  Huerta-Yepez S, Sakai T(他5名)
- Journal Title
  
  Nitric Oxide. 20
  
  Pages: 39-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells2008
- Author(s)
  Yoshida T, Horinaka M, Takara M, Tsuchihashi M, Mukai N, Wakada M, Sakai T
- Journal Title
  
  Environ Health Prev Med. 13
  
  Pages: 281-7
- NAID
  10026957710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Baicalein overcomes TRAIL resistance via two different cell specific pathways in cancer cells but not in normal cells2008
- Author(s)
  Taniguchi H, Yoshida T, Horinaka M, Yasuda T, Goda AE, Konishi M, Wakada M, Kataoka K, Yoshikawa T, Sakai T
- Journal Title
  
  Cancer Res. 68
  
  Pages: 8918-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis2008
- Author(s)
  Yoshida T, Konishi M, Horinaka M, Yasuda T, Goda AE, Taniguchi H, Yano K, Wakada M, Sakai T
- Journal Title
  
  Biochem Biophys Res Commun. 375
  
  Pages: 129-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells2008
- Author(s)
  Kong D, Aoki S, Sowa Y, Sakai T, Kobayashi M. Smenospongine
- Journal Title
  
  Mar Drugs 6
  
  Pages: 480-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression2008
- Author(s)
  Matsuzaki Y, Koyama M, Hitomi T, Yokota T, Kawanaka M, Nishikawa A, Germain D, Sakai T
- Journal Title
  
  Oncol Rep. 19
  
  Pages: 721-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] a novel histone deacetylase inhibitor, exhibits antitumor activity with selective, sustained accumulation of acetylated histones in tumors in the WiDr xenograft model2008
- Author(s)
  Shindoh N, Sowa Y(他13名), Sakai T(他13名)YM753
- Journal Title
  
  Int J Oncol. 32
  
  Pages: 545-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with TRAIL2008
- Author(s)
  Yasuda T, Yoshida T, Goda AE, Horinaka M, Yano K, Shiraishi T, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Mol Cancer Res 6
  
  Pages: 1852-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells2008
- Author(s)
  Takagi K, Sowa Y, Cevik OM, Nakanishi R, Sakai T
- Journal Title
  
  Int J Oncol. 32
  
  Pages: 1105-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole2008
- Author(s)
  Goda AE, Yoshida T, Horinaka M, Yasuda T, Shiraishi T, Wakada M, Sakai T
- Journal Title
  
  Oncogene. 27
  
  Pages: 3455-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Halocynthiaxanthin and peridinin, two dietary carotenoids, sensitize colon cancer cell lines to the death ligand TRAIL2007
- Author(s)
  Yoshida T, Maoka T, Das SK, Kanazawa K, Horinaka M, Wakada M, Satomi, Y, Nishino H, Sakai T
- Journal Title
  
  Mol Cancer Res. 5
  
  Pages: 615-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells2007
- Author(s)
  Yokota T, Matsuzaki Y(他9名), Sakai T(他9名)Sesamin
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1447-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Identification of JTP-70902, a p15^<INK4b>-inductive compound, as a novel MEK1/2 inhibitor2007
- Author(s)
  Yamaguchi T, Yoshida T, Kurachi R, Kakegawa J, Hori Y, Nanayama T, Hayakawa K, Abe H, Takagi K, Matsuzaki Y, Koyama M, Yogosawa S, Sowa Y, Yamori T, Tajima N, Sakai T
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1809-16
- NAID
  10020119466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Glycosylation modulates TRAIL-R1/death receptor 4 protein : different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin2007
- Author(s)
  Yoshida T, Shiraishi T, Horinaka M, Wakada M, Sakai T
- Journal Title
  
  Oncol Rep. 18
  
  Pages: 1239-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis : up-regulation of DR5 and inhibition of Yin Yang 12007
- Author(s)
  Baritaki S, Sakai T(他3名)
- Journal Title
  
  Mol Cancer Ther. 6
  
  Pages: 1387-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] ZD1839 induces p15^<INK4b> and causes G1 arrest by inhibiting the MAPK/ERK pathway2007
- Author(s)
  Koyama M, Matsuzaki Y, Yogosawa S, Hitomi T, Kawanaka M, Sakai T
- Journal Title
  
  Mol Cancer Ther. 6
  
  Pages: 1579-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis2007
- Author(s)
  Yoshida T, Shiraishi T, Horinaka M, Nakata S, Yasuda T, Goda AE, Wakada M, Mizutani Y, Miki T, Nishikawa A, Sakai T
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1417-23
- NAID
  10019998746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Vitamin K2 inhibits the proliferation of HepG2 cells by up-regulating the transcription of p21 gene2007
- Author(s)
  Liu W, Sakai T(他11名)
- Journal Title
  
  Hepatol Res. 37
  
  Pages: 360-5
- NAID
  10020163979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] The plant alkaloid cryptolepine induces p21^<WAF1/CIP1> and cell cycle arrest in a human osteosarcoma cell line2007
- Author(s)
  Matsui TA, Sowa Y(他8名), Sakai T(他8名)
- Journal Title
  
  Int J Oncol. 31
  
  Pages: 915-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo2007
- Author(s)
  Matsui TA, Murata H, Sakabe T, Sowa Y, Horie N, Nakanishi R, Sakai T, Kubo T
- Journal Title
  
  Oncol Rep. 18
  
  Pages: 1263-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Oct-1 is involved in the transcriptional repression of the p15^<INK4b> gene2007
- Author(s)
  Hitomi T, Matsuzaki Y, Yasuda S, Kawanaka M, Yogosawa S, Koyama M, Tantin D, Sakai T
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 1087-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines2007
- Author(s)
  Kouhara J, Yoshida T, Nakata S, Horinaka M, Wakada M, Ueda Y, Yamagishi H, Sakai T
- Journal Title
  
  Int J Oncol. 30
  
  Pages: 679-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Prognostic significance of thymidylate synthase expression in patients with prostate cancer undergoing radical prostatectomy2007
- Author(s)
  Li Y, Sakai T(他8名)
- Journal Title
  
  Urology. 69
  
  Pages: 988-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Lysocellin, a metabolite of the novel drug 'alopestatin', induces G1 arrest and prevents cytotoxicity induced by etoposide2006
- Author(s)
  Takahara Y, Yogosawa S(他12名), Sakai T(他12名)
- Journal Title
  
  Int J Oncol. 28
  
  Pages: 823-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 15-Deoxy-Δ^<12, 14>-prostaglandin J_2 induces death receptor 5 expression through mRNA stabilization independently of PPARγ and potentiates TRAIL-induced apoptosis2006
- Author(s)
  Nakata S, Yoshida T, Shiraishi T, Horinaka M, Kouhara J, Wakada M, Sakai T
- Journal Title
  
  Mol Cancer Ther. 5
  
  Pages: 1827-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] A novel synthetic drug, LB-18, closely related to lembehyne-A derived from a marine sponge, induces caspase-independent cell death to human neuroblastoma cells2006
- Author(s)
  Izumi M, Yogosawa S, Aoki S, Watanabe H, Kamiyama J, Takahara Y, Sowa Y, Kobayashi M, Hosoi H, Sugimoto T, Sakai T
- Journal Title
  
  Int J Oncol. 29
  
  Pages: 169-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera, abrogates TRAIL resistance in leukemia cells2006
- Author(s)
  Hasegawa H, Yoshida T(他14名), Sakai T(他14名)
- Journal Title
  
  Blood. 107
  
  Pages: 679-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner2006
- Author(s)
  Aoki S, Kong D, Suna H, Sowa Y, Sakai T, Setiawan A, Kobayashi M
- Journal Title
  
  Biochem Biophys Res Commun. 342
  
  Pages: 101-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Sulforaphane enhances TRAIL-induced apoptosis through the induction of DR5 expression in human osteosarcoma cells2006
- Author(s)
  Matsui TA, Sowa Y, Yoshida T, Murata H, Horinaka M, Wakada M, Nakanishi R, Sakabe T, Kubo T, Sakai T
- Journal Title
  
  Carcinogenesis. 27
  
  Pages: 1768-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand2006
- Author(s)
  Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, Sakai T
- Journal Title
  
  Mol Cancer Ther. 5
  
  Pages: 945-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Artepillin C in Brazilian propolis induces G_0/G_1 arrest via stimulation of Cip1/p21 expression in human colon cancer cells2005
- Author(s)
  Shimizu K, Das SK, Hashimoto T, Sowa Y, Yoshida T, Sakai T, Matsuura Y, Kanazawa K
- Journal Title
  
  Mol Carcinog. 44
  
  Pages: 293-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Inhibitory effects of cancer cell proliferation by novel histone deacetylase inhibitors involve p21/WAF1 induction and G2/M arrest2005
- Author(s)
  Maeda T, Nagaoka Y, Kawai Y, Takagaki N, Yasuda C, Yogosawa S, Sowa Y, Sakai T, Uesato S
- Journal Title
  
  Biol Pharm Bull. 28
  
  Pages: 849-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Differential response at the hGABP/E4TF1 site of retinoblastoma gene promoter in human testicular seminoma cells2005
- Author(s)
  Shiraishi T, Yoshida T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Oncol Rep. 13
  
  Pages: 871-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Galectin-1 interacts with the α5β1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p272005
- Author(s)
  Fischer C, Sakai T(他8名)
- Journal Title
  
  J Biol Chem. 280
  
  Pages: 37266-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Quercetin induces gadd45 expression through a p53-independent pathway2005
- Author(s)
  Yoshida T, Maeda A, Horinaka M, Shiraishi T, Nakata S, Wakada M, Yogosawa S, Sakai T
- Journal Title
  
  Oncol Rep. 14
  
  Pages: 1299-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] The combination of TRAIL and luteolin enhances apoptosis in human cervical cancer HeLa cells2005
- Author(s)
  Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, Nakanishi R, Nishino H, Sakai T
- Journal Title
  
  Biochem Biophys Res Commun 333
  
  Pages: 833-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] A new cancer diagnostic system based on a CDK profiling technology2005
- Author(s)
  Ishihara H, Sowa Y(他16名), Sakai T(他16名)
- Journal Title
  
  Biochem Biophys Acta. 1741
  
  Pages: 226-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway.2005
- Author(s)
  Takagaki, N., Sowa, Y., Oki, T., Nakanishi, R., Yogosawa, S., Sakai, T.
- Journal Title
  
  International Journal of Oncology 26
  
  Pages: 185-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] INK4 family-a promising target for'gene-regulating chemoprevention'and 'molecular-targeting prevention'of cancer-2005
- Author(s)
  Matsuzaki Y, Sakai T
- Journal Title
  
  Environ Health Prev Med 10
  
  Pages: 72-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Tunicamycin enhances TRAIL-induced apoptosis in human prostate cancer cells2005
- Author(s)
  Shiraishi T, Yoshida T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Cancer Res. 65
  
  Pages: 6364-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Luteolin induces apoptosis via death receptor 5 up-regulation in human malignant tumor cells2005
- Author(s)
  Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, Nakanishi R, Nishino H, Matsui H, Sakai T
- Journal Title
  
  Oncogene. 24
  
  Pages: 7180-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway2005
- Author(s)
  Takagaki N, Sowa Y, Oki T, Nakanishi R, Yogosawa S, Sakai T
- Journal Title
  
  Int J Oncol. 26
  
  Pages: 185-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Hes1 directly controls cell proliferation through the transcriptional repression of p27^<Kip1>2005
- Author(s)
  Murata K, Sakai T(他6名)
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 4262-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein2005
- Author(s)
  Yoshida T, Shiraishi T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T
- Journal Title
  
  Cancer Res. 65
  
  Pages: 5662-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Fucoxanthin induces cell cycle arrest at G_0/G_1 phase in human colon carcinoma cells through up-regulation of p21^<WAF1/Cip1>2005
- Author(s)
  Das SK, Hashimoto T, Shimizu K, Yoshida T, Sakai T, Sowa Y, Komoto A, Kanazawa K
- Journal Title
  
  Biochim Biophys Acta. 1726
  
  Pages: 328-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 15-Deoxy-Δ^<12, 14>-prostaglandin J_2 activates the expression of p15^<INK4b> gene, a cyclin-dependent kinase inhibitor2005
- Author(s)
  Matsuzaki Y, Koyama M, Hitomi T, Takaoka Y, Kawanaka M, Sakai T
- Journal Title
  
  Int J Oncol. 27
  
  Pages: 497-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells.2004
- Author(s)
  Nakata, S., Yoshida, T., Horinaka, M., Shiraishi, T., Wakada, M., Sakai, T.
- Journal Title
  
  Oncogene 23
  
  Pages: 6261-6271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Genistein induces gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line.2004
- Author(s)
  Oki, T., Sowa, Y., Hirose, T., Takagaki, N., Horinaka, M., Nakanishi, R., Yasuda, C., Yoshida, T., Kanazawa, M., Satomi, Y., Nishino, H., Miki, T., Sakai, T.
- Journal Title
  
  FEBS Letters 577
  
  Pages: 55-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Histone deacetylase inhibitors activate p19^<INK4d> gene through Sp1 site in its promoter.2004
- Author(s)
  Yokota, T., Matsuzaki, Y., Miyazawa, K., Zindy, F., Roussel, M., Sakai, T.
- Journal Title
  
  Oncogene 23
  
  Pages: 5340-5349
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Trichostatin A activates p18^<INK4c> gene : Differential activation and cooperation with p19^<INK4d> gene.2004
- Author(s)
  Yokota, T., Matsuzaki, Y., Sakai, T.
- Journal Title
  
  FEBS Letters 574
  
  Pages: 171-175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregulation of p18^<INK4c>.2004
- Author(s)
  Matsuzaki, Y., Takaoka, Y., Hitomi, T., Nishino, H., Sakai, T.
- Journal Title
  
  Oncogene 23
  
  Pages: 5409-5414
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Indole-3-carbinol(I3C) activates the cyclin-dependent kinase inhibitor p15^<INK4b> gene.2004
- Author(s)
  Matsuzaki, Y., Koyama, M., Hitomi, T., Kawanaka, M., Sakai, T.
- Journal Title
  
  FEBS Letters 576
  
  Pages: 137-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] p15^<INK4b> in HDAC inhibitor-induced growth arrest.2003
- Author(s)
  Hitomi, T., Matsuzaki, Y., Yokota, T., Takaoka, Y., Sakai, T.
- Journal Title
  
  FEBS Letters 554
  
  Pages: 347-350
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Isoliquiritigenin inhibits the growth of prostate cancer.2003
- Author(s)
  Kanazawa, M., Satomi, Y., Mizutani, Y., Ukimura, O., Kawauchi, A., Sakai, T., Baba, M., Okuyama, T., Nishino, H., Miki, T.
- Journal Title
  
  European Urology 43
  
  Pages: 580-586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Regulation of the growth arrest and DNA damage-inducible gene 45(GADD45) by peroxisome proliferator-activated receptor gamma in vascular smooth muscle cells.2003
- Author(s)
  Bruemmer, D., Yin, F., Liu, J., Berger, J.P., Sakai, T., Blaschke, F., Fleck, E., Van Herle, A.J., Forman, B.M., Law, R.E.
- Journal Title
  
  Circulation Research 93
  
  Pages: 38-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] DNA damage induces transcriptional activation of p73 by removing C-EBPα repression on E2F1.2003
- Author(s)
  Marabese, M., Vikhankaya, F., Rainelli, C., Sakai, T., Broggini, M.
- Journal Title
  
  Nucleic Acids Research 31
  
  Pages: 6624-6632
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] 15-deoxy-Δ^<12,14>-prostaglandin J_2 induces apoptosis through activation of the CHOP gene in HeLa cells.2003
- Author(s)
  Saito, S., Takahashi, S., Takagaki, N., Hirose, T., Sakai, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications 311
  
  Pages: 17-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] p53-independent induction of Gadd45 by histone deacetylase inhibitor : coordinate regulation by transcription factors Oct-1 and NF-Y.2003
- Author(s)
  Hirose, T., Sowa, Y., Takahashi, S., Saito, S., Yasuda, C., Shindo, N., Furuichi, K., Sakai, T.
- Journal Title
  
  Oncogene 22
  
  Pages: 7762-7773
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] E7 proteins from oncogenic human papillomavirus types transactivate p73 : role in cervical intraepithelial neoplasia.2002
- Author(s)
  Brooks, L.A., Sullivan, A., O'Nions, J., Bell, A., Dunne, B., Tidy, J.A., Evans, D.J., Osin, P., Vousden, K.H., Gusterson, B., Farrell, P.J., Storey, A., Gasco, M., Sakai, T., Crook, T.
- Journal Title
  
  British Journal of Cancer 86
  
  Pages: 263-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Molecular cloning and characterization of the human p19^<INK4d> gene promoter.2002
- Author(s)
  Matsuzaki, Y., Miyazawa, K., Yokota, T., Hitomi, T., Yamagishi, H., Sakai, T.
- Journal Title
  
  FEBS Letters 517
  
  Pages: 272-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Quercetin enhances tumorigenicity induced by N-Ethyl-N'-Nitro-N-Nitrosoguanidine in the duodenum of mice.2002
- Author(s)
  Matsukawa, Y., Nishino, H., Yoshida, M., Sugihara, H., Katsura, K., Takamatsu, T., Okuzumi, J., Matsumoto, K., Sato-Nishimori, F., Sakai, T.
- Journal Title
  
  Environmental Health and Preventive Medicine 6
  
  Pages: 235-239
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] The characterization of the human Siah-1 promoter.2002
- Author(s)
  Maeda, A., Yoshida, T., Kusuzaki, K., Sakai, T.
- Journal Title
  
  FEBS Letters 512
  
  Pages: 223-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井敏行、堀中真野、増田光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井　敏行、堀中　真野、増田　光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井　敏行、堀中　真野、増田　光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PLANNED-17H06398
[Patent] ＲＢ活性化食品組成物2022
- Inventor(s)
  酒井敏行、堀中真野、増田光治
- Industrial Property Rights Holder
  京都府公立大学法人、築野食品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-036535
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB再活性化能を有する果実とTRAIL誘導能を有する乳酸菌による新規がん予防戦略2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] GGCTの阻害は、AMPK-STAT3-c-Met経路の抑制を介してがん抑制遺伝子RBを活性化する2024
- Author(s)
  谷口恵香, 齋藤友充子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTの阻害はc-Met発現低下を介してがん細胞の増殖を抑制する2024
- Author(s)
  谷口恵香, 齋藤友允子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] GGCTの阻害は、AMPK-STAT3-c-Met経路の抑制を介してがん抑制遺伝子RBを活性化する2024
- Author(s)
  谷口恵香, 齋藤友充子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB再活性化能を有する果実とTRAIL誘導能を有する乳酸菌による新規がん予防戦略2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] 実践的がん予防を目指して-RB再活性化果実飲料の開発-2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 実践的がん予防を目指して-RB再活性化果実飲料の開発-2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 実践的がん予防を目指した、RB再活性化果実飲料の開発2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] 実践的がん予防を目指した、RB再活性化果実飲料の開発2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTの阻害はc-Met発現低下を介してがん細胞の増殖を抑制する2024
- Author(s)
  谷口恵香, 齋藤友允子, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ヤマカガシ ( Rhabdophis tigrinus) の毒による子孫への化学的ケアー2024
- Author(s)
  井上貴斗、森哲、堀中真野、吉永直子、酒井敏行、森直樹
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-21H04714
[Presentation] 実践的がん予防を目指した、RB再活性化果実飲料の開発2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第23回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 実践的がん予防を目指して-RB再活性化果実飲料の開発-2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] RB再活性化能を有する果実とTRAIL誘導能を有する乳酸菌による新規がん予防戦略2024
- Author(s)
  堀中真野, 増田光治, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RET融合遺伝子陽性がんにおけるHER3シグナル活性化を介した初期治療抵抗性機構の解明2023
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ケモプロテオミクスによるMEK阻害剤の細胞死誘導抵抗性機構の解明と新規標的分子RPS5の発見2023
- Author(s)
  渡邉元樹, 朴将源, 加藤千翔, 飯泉陽介, 酒井敏行
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] OH基を有する天然物質の標的タンパク質同定法の開発と抗がんメカニズムの解明2023
- Author(s)
  飯泉陽介, 曽和義広, 後居和佳奈, 青野裕一, 渡邉元樹, 来見田遥一, 亀田倫史, 赤路健一, 北川雅敏, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] OH基を有する抗がん物質の標的タンパク質同定法の開発2023
- Author(s)
  飯泉陽介, 曽和義広, 青野裕一, 渡邉元樹, 酒井敏行
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RB再活性化ジュースの発見2023
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RET融合遺伝子陽性がんにおけるHER3シグナル活性化を介した初期治療抵抗性機構の解明2023
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RET変異がんにおけるHER3活性化を介したセルペルカチニブに対する治療抵抗性に関する基礎的検討2023
- Author(s)
  片山勇輝, 山田忠明, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] OH基を有する抗がん物質の標的タンパク質同定法の開発2023
- Author(s)
  飯泉陽介, 曽和義広, 青野裕一, 渡邉元樹, 酒井敏行
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ケモプロテオミクスによるMEK阻害剤の細胞死誘導抵抗性機構の解明と新規標的分子RPS5の発見2023
- Author(s)
  渡邉元樹, 朴将源, 加藤千翔, 飯泉陽介, 酒井敏行
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 悪性胸膜中皮腫におけるATR阻害薬とAXL阻害薬併用治療の検討2023
- Author(s)
  平井聡一, 片山勇輝, 堀中真野, 酒井敏行, 関戸好孝, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 悪性胸膜中皮腫におけるATR阻害薬とAXL阻害薬併用治療の検討2023
- Author(s)
  平井聡一, 片山勇輝, 堀中真野, 酒井敏行, 関戸好孝, 山田忠明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB再活性化ジュースの発見2023
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27841
[Presentation] KRAS-12C陽性肺がんにおけるAXLの活性化を介したKRAS-G12C阻害薬初期治療抵抗性2023
- Author(s)
  森本健司, 山田忠明, 平井聡一, 片山勇輝, 矢野聖二, 堀中真野, 酒井敏行, 徳田深作, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RB再活性化ジュースの発見2023
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Identification of c-Met as a novel target of γ-glutamylcyclotrasnferase in a prostate cancer cell line2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Identification of c-Met as a novel target of γ-glutamylcyclotrasnferase in a prostate cancer cell line2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] OH基を有する天然物質の標的タンパク質同定法の開発と抗がんメカニズムの解明2023
- Author(s)
  飯泉陽介, 曽和義広, 後居和佳奈, 青野裕一, 渡邉元樹, 来見田遥一, 亀田倫史, 赤路健一, 北川雅敏, 酒井敏行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] KRAS-12C陽性肺がんにおけるAXLの活性化を介したKRAS-G12C阻害薬初期治療抵抗性2023
- Author(s)
  森本健司, 山田忠明, 平井聡一, 片山勇輝, 矢野聖二, 堀中真野, 酒井敏行, 徳田深作, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 新規がん予防標的γ-グルタミルシクロトランスフェラーゼの阻害は、c-Met発現低下を介してがん細胞の増殖を抑制する2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  がん予防学術大会2023金沢（第30回日本がん予防学会)
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 新規がん予防標的γ-グルタミルシクロトランスフェラーゼの阻害は、c-Met発現低下を介してがん細胞の増殖を抑制する2023
- Author(s)
  齋藤友充子, 谷口恵香, 飯居宏美, 堀中真野, 影山進, 中田晋, 浮村理, 酒井敏行
- Organizer
  がん予防学術大会2023金沢（第30回日本がん予防学会)
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RET変異がんにおけるHER3活性化を介したセルペルカチニブに対する治療抵抗性に関する基礎的検討2023
- Author(s)
  片山勇輝, 山田忠明, 谷村恵子, 森本健司, 矢野聖二, 堀中真野, 酒井敏行, 高山浩一
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したLorlatinibの初期治療抵抗性機構の解明2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気的解糖を促進する2022
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RB活性化果実飲料の発見2022
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんにおけるJNK/c-Jun経路活性化を介したALK阻害薬抵抗性機構の解明2022
- Author(s)
  谷村恵子, 堀中真野, 米田和恵, 矢野聖二, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK融合遺伝子陽性肺がんにおけるJNK/c-Jun経路活性化を介したALK阻害薬抵抗性機構の解明2022
- Author(s)
  谷村恵子, 堀中真野, 米田和恵, 矢野聖二, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB活性化果実飲料の発見2022
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] サリチル酸はヒト大腸がん細胞のRPS3に結合し、CDK4発現抑制と細胞周期のG1期停止を誘導する2022
- Author(s)
  今井綾香, 堀中真野, 青野裕一, 飯泉陽介, 高倉秀樹, 小野寿子, 谷口恵香, 安田周祐, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  第21回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 多発性骨髄腫に対するRSK2、AKT二重阻害療法開発の理論的基盤2022
- Author(s)
  黒田純也, 塚本拓, 堀中真野, 酒井敏行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気的解糖を促進する2022
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したロルラチニブ初期治療抵抗性の解明とその克服2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 小笹裕晃, 山田忠明
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] サリチル酸はヒト大腸がん細胞のRPS3に結合し、CDK4発現抑制と細胞周期のG1期停止を誘導する2022
- Author(s)
  今井綾香, 堀中真野, 青野裕一, 飯泉陽介, 高倉秀樹, 小野寿子, 谷口恵香, 安田周祐, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] RB活性化果実飲料の発見2022
- Author(s)
  増田光治, 堀中真野, 安田周祐, 森田美枝, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  第21回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 多発性骨髄腫に対するRSK2、AKT二重阻害療法開発の理論的基盤2022
- Author(s)
  黒田純也, 塚本拓, 堀中真野, 酒井敏行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気的解糖を促進する2022
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したLorlatinibの初期治療抵抗性機構の解明2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したロルラチニブ初期治療抵抗性の解明とその克服2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 小笹裕晃, 山田忠明
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] サリチル酸はヒト大腸がん細胞のRPS3に結合し、CDK4発現抑制と細胞周期のG1期停止を誘導する2022
- Author(s)
  今井綾香, 堀中真野, 青野裕一, 飯泉陽介, 高倉秀樹, 小野寿子, 谷口恵香, 安田周祐, 西幹栄美, 石川秀樹, 武藤倫弘, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 多発性骨髄腫に対するRSK2、AKT二重阻害療法開発の理論的基盤2022
- Author(s)
  黒田純也, 塚本拓, 堀中真野, 酒井敏行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18407
[Presentation] 延命草成分オリドニンはp38とNF-kBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  第21回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  がん予防学術大会2022
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんにおけるJNK/c-Jun経路活性化を介したALK阻害薬抵抗性機構の解明2022
- Author(s)
  谷村恵子, 堀中真野, 米田和恵, 矢野聖二, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したLorlatinibの初期治療抵抗性機構の解明2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK融合遺伝子陽性肺がんにおけるEGFRシグナル活性化を介したロルラチニブ初期治療抵抗性の解明とその克服2022
- Author(s)
  片山勇輝, 谷村恵子, 森本健司, 堀中真野, 酒井敏行, 小笹裕晃, 山田忠明
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK肺癌におけるALKとHER3の共阻害による新たな治療戦略2021
- Author(s)
  谷村恵子, 山田忠明, 米田和恵, 堀中真野, 酒井敏行, 上原久典, 矢野聖二, 片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] PIK3CA変異大腸癌細胞においてグルタミン代謝阻害がアスピリンに対する感受性を促進する2021
- Author(s)
  朴将源, 渡邉元樹, 飯塚まひろ, 曽和義広, 増田光治, 飯泉陽介, 成田匠, 佐竹悠良, 酒井敏行, 武藤倫弘
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ALK肺癌におけるALKとHER3の共阻害による新たな治療戦略2021
- Author(s)
  谷村恵子, 山田忠明, 米田和恵, 堀中真野, 酒井敏行, 上原久典, 矢野聖二, 片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] シスチン・グルタミン酸トランスポーターxCTの阻害はROS依存的にvorinostatの感受性を増強する2021
- Author(s)
  渡邉元樹, 朴将源, 酒井敏行
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] PIK3CA変異大腸癌細胞においてグルタミン代謝阻害がアスピリンに対する感受性を促進する2021
- Author(s)
  朴将源,　渡邉元樹, 飯塚まひろ, 曽和義広, 増田光治, 飯泉陽介, 成田匠, 佐竹悠良, 酒井敏行, 武藤倫弘
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] EGFR-T790M変異陽性肺がんの生物学的特徴に関する基礎的検討2021
- Author(s)
  片山勇輝, 西岡直哉, 大倉直子, 森本健司, 谷村恵子, 堀中真野, 酒井敏行, 矢野聖二, 山田忠明
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] シスチン・グルタミン酸トランスポーターxCTの阻害はROS依存的にvorinostatの感受性を増強する2021
- Author(s)
  渡邉元樹, 朴将源, 酒井敏行
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野，酒井敏行
- Organizer
  第91回　日本衛生学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1 alpha発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回　日本衛生学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 細胞外グルタミン濃度はがん予防薬の感受性に影響する2021
- Author(s)
  渡邉元樹, 朴将源, 宮本景子, 曽和義広, 飯泉陽介, 増田光治, 成田匠, 中尾俊雅, 武藤倫弘, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 「先制医療」の実現に向けた戦略的研究2021
- Author(s)
  堀中真野, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22773
[Presentation] アカデミア発新薬の上市を目指した企業への導出の実際2021
- Author(s)
  酒井敏行
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-19K22773
[Presentation] アカデミア発新薬の上市を目指した企業への導出の実際2021
- Author(s)
  酒井敏行
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ALK肺癌におけるALKとHER3の共阻害による新たな治療戦略2021
- Author(s)
  谷村恵子, 山田忠明, 米田和恵, 堀中真野, 酒井敏行, 上原久典, 矢野聖二, 片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 細胞外グルタミン濃度はがん予防薬の感受性に影響する2021
- Author(s)
  渡邉元樹, 朴将源, 宮本景子, 曽和義広, 飯泉陽介, 増田光治, 成田匠, 中尾俊雅, 武藤倫弘, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] EGFR-T790M変異陽性肺がんの生物学的特徴に関する基礎的検討2021
- Author(s)
  片山勇輝, 西岡直哉, 大倉直子, 森本健司, 谷村恵子, 堀中真野, 酒井敏行, 矢野聖二, 山田忠明
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] EGFR-T790M変異陽性肺がんの生物学的特徴に関する基礎的検討2021
- Author(s)
  片山勇輝, 西岡直哉, 大倉直子, 森本健司, 谷村恵子, 堀中真野, 酒井敏行, 矢野聖二, 山田忠明
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導しワールブルク効果を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 窪田成寿, 河内明宏, 中田晋
- Organizer
  第20回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規がん予防標的GGCTは、がん細胞にHIF-1α発現を誘導して好気性解糖を促進する2021
- Author(s)
  谷口恵香, 影山進, 茂山千愛美, 安藤翔太, 飯居宏美, 芦原英司, 堀中真野, 酒井敏行, 河内明宏, 中田晋
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22773
[Presentation] アスピリン、メサラジン併用による大腸がん予防効果の検討2020
- Author(s)
  高倉英樹，堀中真野，今井綾香，武藤倫弘，酒井敏行
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 延命草の苦味成分rabdosianone Ⅰはミトコンドリア内膜タンパク質ANT2とPHB2に直接結合し、thymidylate synthaseの発現を抑制する2020
- Author(s)
  渡邉元樹, 酒井敏行
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression．2020
- Author(s)
  楳村史織, 曽和義広, 飯泉陽介, 酒井敏行
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ファースト/ベスト・イン・クラスのMEK阻害剤トラメチニブ（商品目メキニスト） -その発見に至った経緯-2020
- Author(s)
  酒井敏行
- Organizer
  第5回橋渡し研究戦略的推進プログラムシンポジウム
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] EGFR遺伝子変異陽性肺がんの初期治療抵抗性に対する新規AXL阻害薬ONO-7475の効果2020
- Author(s)
  大倉直子, 西岡直哉, 谷村恵子, 矢野聖二, 小崎龍平, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] BRCAness誘導分子の探索2020
- Author(s)
  小野寿子, 堀中真野, 酒井敏行
- Organizer
  第65回日本人類遺伝学会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] アスピリン、メサラジン併用による大腸がん予防効果の検討2020
- Author(s)
  高倉英樹，堀中真野，今井綾香，武藤倫弘，酒井敏行
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19693
[Presentation] HER3 is a potent therapeutic target for prevention of tolerant cells to ALK inhibitors in ALK-rearranged cancer.2020
- Author(s)
  谷村恵子, 米田和恵, 矢野聖二, 堀中真野, 酒井敏行, 片山量平, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ALK融合遺伝子陽性肺がんの初期治療抵抗性機構の解明とその克服法の開発2020
- Author(s)
  谷村恵子, 山田忠明, 岡田康太郎, 米田和恵, 堀中真野, 酒井敏行, 矢野聖二, 片山量平
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 「先制医療」の時代における日本衛生学会の役割2020
- Author(s)
  酒井敏行
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] HER3 is a potent therapeutic target for prevention of tolerant cells to ALK inhibitors in ALK-rearranged cancer．2020
- Author(s)
  谷村恵子, 米田和恵, 矢野聖二, 堀中真野, 酒井敏行, 片山量平, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] xCT inhibition increases sensitivity to vorinostat in a ROS-dependent manner.2020
- Author(s)
  渡邉元樹, 宮本景子, 朴将源, 阪口晃一, 田口哲也, 曽和義広, 飯泉陽介, 増田光治, 成田匠, 鱧屋隆博, 酒井敏行, 武藤倫弘
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ALK融合遺伝子陽性肺がんの初期治療抵抗性機構の解明とその克服法の開発2020
- Author(s)
  谷村恵子, 山田忠明, 岡田康太郎, 米田和恵, 堀中真野, 酒井敏行, 矢野聖二, 片山量平
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression.2020
- Author(s)
  楳村史織, 曽和義広, 飯泉陽介, 酒井敏行
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] EGFR遺伝子変異陽性肺がんの初期治療抵抗性に対する新規AXL阻害薬ONO-7475の効果2020
- Author(s)
  大倉直子, 西岡直哉, 谷村恵子, 矢野聖二, 小崎龍平, 堀中真野, 酒井敏行, 山田忠明
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 延命草の苦味成分rabdosianone Ⅰはミトコンドリア内膜タンパク質ANT2とPHB2に直接結合し、thymidylate synthaseの発現を抑制する2020
- Author(s)
  渡邉元樹, 酒井敏行
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 「先制医療」の時代における日本衛生学会の役割2020
- Author(s)
  酒井敏行
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ONO-7475, a novel AXL inhibitor, suppresses the adaptive resistance to initial EGFR-TKI treatment in EGFR-mutated NSCLC.2020
- Author(s)
  大倉直子, 谷口寛和, 谷村恵子, 堀中真野, 酒井敏行, 田中昴平, 小崎龍平, 矢野聖二, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ONO-7475, a novel AXL inhibitor, suppresses the adaptive resistance to initial EGFR-TKI treatment in EGFR-mutated NSCLC.2020
- Author(s)
  大倉直子, 谷口寛和, 谷村恵子, 堀中真野, 酒井敏行, 田中昴平, 小崎龍平, 矢野聖二, 山田忠明
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] xCT inhibition increases sensitivity to vorinostat in a ROS-dependent manner.2020
- Author(s)
  渡邉元樹, 宮本景子, 朴将源, 阪口晃一, 田口哲也, 曽和義広, 飯泉陽介, 増田光治, 成田匠, 鱧屋隆博, 酒井敏行, 武藤倫弘
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] BRCAness誘導分子の探索2020
- Author(s)
  小野寿子, 堀中真野, 酒井敏行
- Organizer
  第65回日本人類遺伝学会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ファースト/ベスト・イン・クラスのMEK阻害剤トラメチニブ（商品目メキニスト） -その発見に至った経緯-2020
- Author(s)
  酒井敏行
- Organizer
  第5回橋渡し研究戦略的推進プログラムシンポジウム
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ファースト・イン・クラスかつベスト・イン・クラスのMEK阻害剤トラメチニブ：過去、現在、未来2019
- Author(s)
  酒井敏行
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] がん抑制遺伝子RBを萃点として捉えた、新しいがんの予防法、診断法、治療法の開発2019
- Author(s)
  酒井敏行
- Organizer
  国立研究開発法人医薬基盤・健康・栄養研究所　国立健康・栄養研究所　健栄研セミナー
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] アカデミアと企業の相互理解の難しさ2019
- Author(s)
  酒井敏行
- Organizer
  第10回スクリーニング学研究会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] アカデミアと企業の相互理解の難しさ2019
- Author(s)
  酒井敏行
- Organizer
  第10回スクリーニング学研究会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 耐久高校での夢～画期的抗がん剤開発の実現2019
- Author(s)
  酒井敏行
- Organizer
  令和元年度関西耐久会　特別講演
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 耐久高校での夢～画期的抗がん剤開発の実現2019
- Author(s)
  酒井敏行
- Organizer
  令和元年度関西耐久会　特別講演
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] スリンダク代謝体スリンダクスルホンの大腸癌細胞に対する新規標的分子の同定と作用機序の解析2019
- Author(s)
  堀中真野，青野裕一，飯泉陽介，渡邉元樹，酒井敏行
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 分子標的癌予防医学2019
- Author(s)
  酒井敏行
- Organizer
  ルイ・パストゥール医学研究センター 2019年度バイオ・ソサエティ医学入門講座
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ファースト・イン・クラスのMEK 阻害剤トラメチニブの発見2019
- Author(s)
  酒井敏行
- Organizer
  第3回薬学トップランナー研究講演会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ファースト・イン・クラスのMEK 阻害剤トラメチニブの発見2019
- Author(s)
  酒井敏行
- Organizer
  第3回薬学トップランナー研究講演会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ファースト/ベスト・イン・クラスMEK阻害剤トラメチニブ（商品名メキニスト）等の創薬経験から2019
- Author(s)
  酒井敏行
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] RBを萃点として捉えた新規がん治療法・予防法の開発 -first/best-in-classのMEK阻害剤トラメチニブ及びがん予防ジュースの開発の現状-2019
- Author(s)
  酒井敏行
- Organizer
  国立がん研究センター　セミナー
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 京都府立医大発の画期的抗がん剤 -その歴史と現状-2019
- Author(s)
  酒井敏行
- Organizer
  第13回府民公開講座
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] がん抑制遺伝子RBを萃点として捉えた、新しいがんの予防法、診断法、治療法の開発2019
- Author(s)
  酒井敏行
- Organizer
  国立研究開発法人医薬基盤・健康・栄養研究所　国立健康・栄養研究所　健栄研セミナー
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ファースト・イン・クラスのMEK阻害剤トラメチニブなどの創薬から学んだこと-我が国の産学連携研究のあり方への提言2019
- Author(s)
  酒井敏行
- Organizer
  medU-net年次総会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] スリンダク代謝体の大腸腺腫形成抑制作用における新規標的分子の探索と作用機序の解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] 京都府立医大発の画期的抗がん剤 -その歴史と現状-2019
- Author(s)
  酒井敏行
- Organizer
  第13回府民公開講座
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] スリンダク代謝体であるスリンダクスルホンによる大腸腺腫形成抑制作用の機序解明に向けた新規標的分子の同定2019
- Author(s)
  堀中真野，青野裕一，飯泉陽介，安田周祐，渡邉元樹，谷口知行，酒井敏行
- Organizer
  第26回日本がん予防学会総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting VDAC1 and VDAC2.2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，安田周祐，渡邉元樹，酒井敏行
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03889
[Presentation] 分子標的癌予防医学2019
- Author(s)
  酒井敏行
- Organizer
  ルイ・パストゥール医学研究センター 2019年度バイオ・ソサエティ医学入門講座
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] 新規スリンダクスルホン結合タンパク質VDACによる細胞周期制御のメカニズムの解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行
- Organizer
  第18回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] RBを萃点として捉えた新規がん治療法・予防法の開発 -first/best-in-classのMEK阻害剤トラメチニブ及びがん予防ジュースの開発の現状-2019
- Author(s)
  酒井敏行
- Organizer
  国立がん研究センター　セミナー
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ファースト・イン・クラスのMEK阻害剤トラメチニブなどの創薬から学んだこと-我が国の産学連携研究のあり方への提言2019
- Author(s)
  酒井敏行
- Organizer
  medU-net年次総会・シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] ファースト・イン・クラスかつベスト・イン・クラスのMEK阻害剤トラメチニブ：過去、現在、未来2019
- Author(s)
  酒井敏行
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01079
[Presentation] ファースト/ベスト・イン・クラスMEK阻害剤トラメチニブ（商品名メキニスト）等の創薬経験から2019
- Author(s)
  酒井敏行
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらすcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
- Organizer
  第１７回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] クルクミンによるがん予防効果の分子機構の解析2018
- Author(s)
  飯泉陽介、小野寿子、後居和佳奈、曽和義広、酒井敏行
- Organizer
  第17回　分子予防環境医学研究会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらすcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真美子、曽和義広、酒井敏行
- Organizer
  第17回　分子予防環境医学研究会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] クルクミンによるがん予防効果の分子機構解明の試み2018
- Author(s)
  飯泉陽介、小野寿子、後居和佳奈、曽和義広、酒井敏行
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規エピゲノム併用療法の開発2018
- Author(s)
  曽和義広、酒井敏行
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらす新たな細胞周期調節機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真美子、曽和義広、酒井敏行
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらす新たな細胞周期調節機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
- Organizer
  第８８回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] 新規セサミノール結合蛋白質ANT2によるcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、曽和義広、酒井敏行
- Organizer
  第２２回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] The strategy of molecular-targeting cancer prevention (がんの分子標的予防戦略)2017
- Author(s)
  堀中真野, 飯泉陽介, 渡邉元樹, 増田光治, 曽和義広, 酒井敏行
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2013
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス(金沢)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] メチルグリオキサールは癌細胞において XIAP や survivin の発現を減少させ、TRAIL 感受性を増強する2013
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくば
- Year and Date
  2013-01-01
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] methylglyoxal による XIAP とsurvivin の発現抑制と、TRAIL 誘導性アポトーシスの増強2013
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 酪酸菌による好中球からの TRAIL 放出促進機構とその抗腫瘍効果の検討2012
- Author(s)
  神農雅秀, 堀中真野, 三木恒治, 酒井敏行
- Organizer
  第11回分子予防環境医学研究会
- Place of Presentation
  第11回分子予防環境医学研究会
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2012
- Author(s)
  友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 酪酸菌による好中球からの TRAIL 放出機構の解析とその臨床応用への検討.2012
- Author(s)
  神農雅秀, 堀中真野, 上田崇, 木村泰典, 中村晃和, 本郷文弥, 三神一哉, 高羽夏樹, 河内明宏, 酒井敏行, 三木恒治
- Organizer
  100回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-04-23
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 酪酸菌による TRAIL 誘導とその抗腫瘍効果の検討-第2 報-.2012
- Author(s)
  堀中真野, 神農雅秀, 三木恒治, 酒井敏行
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンによるRB非依存的なG1期における細胞周期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 大腸癌細胞株に対するインドール-3-カルビノールとガランギンの併用による細胞死増強2011
- Author(s)
  与五沢真吾、渡部公綱、瀧澤香織、曽和義広、酒井敏行
- Organizer
  第10回分子予防環境医学研究会大会
- Place of Presentation
  京都府立医科大学
- Year and Date
  2011-01-21
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 大腸癌細胞株に対するブラシニンの細胞周期停止効果とその分子メカニズム2011
- Author(s)
  泉谷泰行、与五沢真吾、曽和義広、酒井敏行
- Organizer
  第10回分子予防環境医学研究会大会
- Place of Presentation
  京都府立医科大学
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] フラボンによる RB 非依存的 G1 期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  がん予防大会 2011 京都
- Place of Presentation
  京都府立医科大学図書館ホール(京都)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] フラボンによる RB 非依存的な G1 期における細胞周期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 酪酸菌によるTRAIL誘導とその抗腫瘍効果の検討2011
- Author(s)
  神農雅秀、堀中真野、高羽夏樹、三木恒治、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] クルクミンの半量体デヒドロジンゲロンによる細胞増殖抑制効果2011
- Author(s)
  与五沢真吾、安田周祐、山田恭正、曽和義広、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 乳酸菌はヒト末梢血リンパ球からTRAIL産生を誘導することで、ヒト癌細胞に対する細胞傷害活性を増強する2010
- Author(s)
  堀中真野、吉田達士、酒井敏行、甲原純二、岸惇子、赤谷薫
- Organizer
  がん予防学術大会2010札幌
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] インドール-3-カルビノールとゲニステインの併用によるAkt経路及びオートファジー進行阻害を介したアポトーシス増強効果2010
- Author(s)
  与五沢真吾、中村吉隆、泉谷泰行、渡部公綱、大辻英吾、酒井敏行
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cell2010
- Author(s)
  堀中真野、吉田達士、岸惇子、甲原純二、安田孝志、酒井敏行
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] インドール-3-カルビノールとゲニステイン併用による、オートファゴソーム蓄積を伴う癌細胞死誘導2010
- Author(s)
  与五沢真吾、中村吉隆、泉谷泰行、渡部公綱、酒井敏行
- Organizer
  がん予防学術大会2010札幌
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] CDK阻害剤によるDHFR発現抑制を介したMTX感受性増強についての検討2010
- Author(s)
  内山人二、曽和義広、堀中真野、酒井敏行
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 大腸癌細胞株に対するブラシニンの細胞周期停止効果とその分子メカニズム2010
- Author(s)
  泉谷泰行、与五沢真吾、渡部公綱、曽和義広、酒井敏行
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] ヒト白血病におけるCDK阻害薬によるMTX感受性増強についての検討2010
- Author(s)
  内山人二、曽和義広、堀中真野、島崎千尋、谷脇雅史、酒井敏行
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] Histone deacetylase inhibitors and 15-deoxy-Δ^<12,14>-prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Organizer
  AACR 101^<st> Annual Meeting 2010
- Place of Presentation
  Walter E.Washington Convention Center
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] HDAC阻害剤と15-deoxy-Δ^<12,14>-prostaglandin J_2は相乗的にアポトーシスを引き起こす2010
- Author(s)
  小山真、泉谷泰行、ゴーダアハメッド、堀中真野、友杉充宏、中村吉隆、与五沢真吾、曽和義広、酒井敏行
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] Histone deacetylase inhibitors and 15-deoxy-△^<12,14)-prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Organizer
  AACR 101^<st> annual meeting 2010
- Place of Presentation
  Walter E.Washington convention center
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 乳酸菌によるTRAIL発現誘導に着目した癌の分子標的予防2010
- Author(s)
  堀中真野、吉田達士、岸惇子、赤谷薫、安田孝志、甲原純二、酒井敏行
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] インドールー3-カルビノールとガランギンの併用による細胞死増強効果2010
- Author(s)
  与五沢真吾、渡部公綱、瀧澤香織、曽和義広、酒井敏行
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] Chetominの泌尿器癌細胞に対するXIAP分解誘導とTRAIL感受性増強2010
- Author(s)
  矢野公大、堀中真野、吉田達士、安田孝志、谷口浩也、ゴーダアハメッド、中村晃和、河内明宏、三木恒治、酒井敏行
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] HDAC阻害剤と15-deoxy-Δ^<12,14>-prostaglandin J_2の併用療法は相乗的にアポトーシスを引き起こす2010
- Author(s)
  小山真、ゴーダアハメッド、堀中真野、与五沢真吾、曽和義広、酒井敏行
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 食品成分を用いた癌の「分子標的併用予防法」2008
- Author(s)
  酒井敏行, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20015040
[Presentation] 発癌分子を標的とした合理的癌予防法の基礎的研究2008
- Author(s)
  酒井敏行
- Organizer
  第78回日本衛生学会総会
- Place of Presentation
  熊本
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] 発癌分子を標的とした合理的癌予防法の基礎的研究2008
- Author(s)
  酒井敏行
- Organizer
  日本衛生学会
- Place of Presentation
  熊本
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] 発癌分子を標的とした合理的癌予防法の基礎的研究2008
- Author(s)
  酒井敏行
- Organizer
  日本衛生学会
- Place of Presentation
  熊本
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-18032062
[Presentation] 食品成分を用いた癌の「分子標的併用予防法」2008
- Author(s)
  酒井敏行, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] 食品成分を用いた癌の「分子標的併用予防法」2008
- Author(s)
  酒井敏行, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] 発癌分子を標的とした合理的癌予防法の基礎的研究2008
- Author(s)
  酒井敏行
- Organizer
  日本衛生学会
- Place of Presentation
  熊本
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Dietary flavonoids enhance TRAIL-induced apoptosis in Cancer Cells.2007
- Author(s)
  Sakai T., et. al.
- Organizer
  International Conference on Food Factors for Health Promotion
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] p53-RB pathway as a final target for a variety of molecular-targeting chemothera eutic agents2007
- Author(s)
  Sakai T.
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18032062
[Presentation] Dietary flavonoids enhance TRAIL-induced apoptosis in Cancer Cells.2007
- Author(s)
  Sakai T., et. al.
- Organizer
  International Conference on Food Factors for Health Promotion
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Dietary flavonoids enhance TRAIL-induced apoptosis in Cancer Cells2007
- Author(s)
  Sakai T.
- Organizer
  International Conference on Food Factors for Health Promotion
- Place of Presentation
  Kyoto,Japan
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-18032062
[Presentation] p53-RB pathway as a final target for a variety of molecular-targeting chemotherapeutic agents2007
- Author(s)
  Sakai T.
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] p53-RB pathway as a final target for a variety of molecular-targeting chemotherapeutic agents2007
- Author(s)
  Sakai T.
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Aclarubicin enhances TRAIL-induced apoptosis through DR5 up-regulation
- Author(s)
  堀中真野, 吉田達士, 中田晋, 白石匠, 友杉充宏, 三木恒治, 酒井敏行
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] イブプロフェンによるDR5の発現誘導と、TRAIL誘導性アポトーシスの増強
- Author(s)
  藤堂桃子, 堀中真野, 友杉充宏, 曽和義広, 大辻英吾, 酒井敏行
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] methylglyoxalによるXIAPとsurvivinの発現抑制と、TRAIL誘導性アポトーシスの増強
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] メチルグリオキサールは癌細胞においてXIAPやsurvivinの発現を減少させ、TRAIL感受性を増強する
- Author(s)
  堀中真野, 谷口浩也, 吉田達士, 安田周祐, 酒井敏行
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] アクラルビシンはp53非依存的にDR5の発現を誘導し、TRAIL感受性を増強する
- Author(s)
  堀中真野, 吉田達士, 中田晋, 白石匠, 酒井敏行
- Organizer
  日本がん分子標的治療学会第16回学術集会
- Place of Presentation
  小倉
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] 酪酸菌による好中球からのTRAIL放出機構の解析とその臨床応用への検討
- Author(s)
  神農雅秀, 堀中真野, 上田崇, 木村泰典, 中村晃和, 本郷文弥, 三神一哉, 高羽夏樹, 河内明宏, 酒井敏行, 三木恒治
- Organizer
  第100回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659336
[Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導
- Author(s)
  友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-21249042

1. SOWA Yoshihiro (70315935)

# of Collaborated Projects: 17 results

# of Collaborated Products: 49 results
2. HORINAKA Mano (80512037)

# of Collaborated Projects: 15 results

# of Collaborated Products: 150 results
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# of Collaborated Products: 26 results
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76. 朴将源

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SAKAI Toshiyuki 酒井 敏行

酒井 敏行

Research Projects

Research Products

Co-Researchers

遺伝性乳がん卵巣がん症候群に対する先制医療の開発Principal Investigator

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Development of novel molecular target combination therapy for osteosarcoma

Principal Investigator

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Development of preemptive medical care for pre-symptomatic MEN1 gene mutation carriers

Principal Investigator

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Development of preemptive medicine against RB-mutated malignanciesPrincipal Investigator

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Bufadienolides, a snake defense substance: Investigation of the mechanism of dietary evolution.

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Basic research for prevention of arteriosclerosis by cancer preventive ingredients with RB activation ability

Principal Investigator

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Tailor-maid cancer prevention towards the era of preemptive medicine.Principal Investigator

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Preventive strategy against arsenic carcinogenesis by TRAIL pathway activation and RB activation

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A new colorectal cancer chemoprevention method to reduce side effects of aspirinPrincipal Investigator

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Research of molecular-targeting prevention against inflammatory diseases using chemical biology.Principal Investigator

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Molecular-targeting prevention against human papilloma virus-positive cervical cancerPrincipal Investigator

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Application of molecular-targeting cancer prevention to human intervention study.Principal Investigator

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Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the novel mechanisms of carcinogenesis induced by the cigarette and development of cancer prevention for carcinogenesis by sidestream smokePrincipal Investigator

Principal Investigator

Project Period (FY)

SAKAI Toshiyuki 酒井敏行

酒井敏行