YUASA HIROAKI 湯浅博昭

… Alternative Names

Hiroaki Yuasa 湯浅博昭

YUASA Hiroaki 湯浅博昭

湯浅博和ユアサヒロアキ

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Researcher Number	20191471
Other IDs
External Links
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(薬学), 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 名古屋市立大学, 医薬学総合研究院(薬学), 教授 2011 – 2015: 名古屋市立大学, 薬学研究科(研究院), 教授 2014: 名古屋市立大学, 大学院薬学研究科, 教授 2012: 名古屋市立大学, 大学院・薬学研究科, 教授 2007 – 2010: Nagoya City University, Graduate School of Pharmaceutical Sciences, Professor … More 2006: 名古屋市立大学, 大学院薬学研究科, 教授 2004 – 2005: 名古屋市立大学, 大学院・薬学研究科, 教授 2002: Graduate School of Pharmaceutical Sciences, Professor, 大学院・薬学研究科, 教授 2000 – 2001: Nagoya City University, Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授 1999: 名古屋市立大学, 薬学部, 助教授 1992 – 1997: 名古屋市立大学, 薬学部, 助教授 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / 医薬分子機能学 / Physical pharmacy Except Principal Investigator Physical pharmacy / Basic Section 47060:Clinical pharmacy-related / Medical pharmacy
Keywords	Principal Investigator トランスポーター / 担体輸送 / carrier-mediated transport / 吸収 / 創薬標的 / グリセロール / 薬物送達 / HCT-15 cell / transporter / glycerol … More / HCT-15細胞 / CYP3A / 小腸 / ナトリウム依存性 / ラット / コリン / 前立腺 / プトレシン / スペルミン / スペルミジン / ポリアミン / competitive inhibition / differentiation / Nat-dependent transport / 酪酸 / Na^+依存性 / ジグリセロール / モノアセチン / 競合阻害 / 分化誘導 / polyol / intestine / rat / Na^+-dependent transport / クロラムフェニコール / アルコール / 多価アルコール / NCT-15細胞 / 腸管 / Na^+依存性輸送 / P-glycoprotein / cyclosporine / riboflavin / first-pass metabolism / small intestine / colon / 徐放剤 / 細胞生物学 / 薬物動態学 / ニフェジピン / 除放剤 / タウロコール酸 / グルコース / P糖タンパク質 / シクロスポリン / リボフラビン / 初回通過代謝 / 結腸 / 核酸塩基 / チャネル / アクアポリン10 / 抗アレルギー薬 / 免疫 / 小胞体 / 樹状細胞 / アクアグリセロポリン / アクアポリン / クローニング / D-キシロース / L-グルコース / 腸管膜透過 / 腸管吸収 / 胃排出 / 生理機構 / 経口薬物吸収 … More Except Principal Investigator fractionated heparin / 分画ヘパリン / トランスポーター / scavenger receptor / ラット / クッパー細胞 / 肝実質細胞 / スカベンジャー受容体 / Lactobacillus casei / 腹腔マクロファージ / rat Kupffer cells / rat liver parenchymal cells / エンドサイトーシス / 肝取り込み / ラットクッパー細胞 / ラット肝実質細胞 / 薬物吸収 / ビタミン / 相互作用 / 基質認識機構 / 薬物間相互作用 / 迅速機能評価 / 蛍光 / 神経伝達 / シナプス小胞 / モノアミン / 高尿酸血症 / リソソーム / 痛風 / 尿酸結晶 / 尿酸 / small intestine / nifedipine / rat / first-pass metabolism / absorption / probiotics / CYP3A / 反転腸管 / 1回灌流法 / 小腸 / ニフェジピン / 初回通過代謝 / 消化管吸収 / プロバイオティクス / brain capillary endothelial cell / peritoneal macrophage / Kupffer cell / liver parenchymal cell / targeting / macromolecular drug / マクロファージ / クローニング / ターゲッラィング / 脳毛細血管内皮細胞 / ターゲッティング / 高分子量薬物 / apparent release constant / intemalization / surface binding / peritoneal macrophages / 血漿タンパクとの相互作用 / スカベンジャー様受容体 / スカベンジ-受容体 / 見かけの放出速度定数 / 内在化 / 表面結合 / competitive inhibition of uptake / macromolecule-macromolecule interaction / receptor-mediated endocytosis / molecular weight dependency / スキャベンジャーリセプター / 初代培養 / 競合的取り込み阻害 / 高分子-高分子相互作用 / 受容体介在性エンドサイトーシス / 分子量依存性 / albumin / a-globulin / plasma protein / anion transport system / transport inhibitor / dose-dependent uptake / rat parenchymal hepatocyte / 血清アルブミン / alpha-グロブリン / 血清アルグミン / α-グロブリン / 血漿蛋白 / アニオン輸送系 / 輸送阻害剤 / 濃度依存的肝取込み / ラット培養肝実質細胞 / de novo / プリン塩基 / プリン核酸 / ガンシクロビル / ENBT1 / 代謝酵素 / 促進拡散 / 核酸塩基 Less

新規小胞膜局在型モノアミントランスポーターの機能解析と創薬標的としての有望性評価
- Principal Investigator
  
  保嶋智也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
新規コリントランスポーター類の分子機能と生理的及び薬物動態的役割Principal Investigator
- Principal Investigator
  
  湯浅博昭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of substrate recognition mechanism of SLC19A3 to establish the molecular basis for medical applications
- Principal Investigator
  
  山城貴弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of molecular mechanism that triggers onset of gout from hyperuricemia
- Principal Investigator
  
  Yasujima Tomoya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of the Function and Physiological Role of a Novel Polyamine TransporterPrincipal Investigator
- Principal Investigator
  
  Hiroaki Yuasa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Nucleobase Transport Function of Aquaporin 10: Its Role in the Intestinal Absorption of Nucleobases and Analogous DrugsPrincipal Investigator
- Principal Investigator
  
  Yuasa Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Physiological role of a novel nucleobase transporter in the utilization of extracellular purine nucleobases
- Principal Investigator
  
  INOUE Katsuhisa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
  Nagoya City University
Functional Characteristics of a Novel Transporter Specifically Expressed in the Endoplasmic Reticulum in Dendritic Cells and its Role in Immune SystemPrincipal Investigator
- Principal Investigator
  
  YUASA Hiroaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Identification and Functional Analysis of the Na^+-Dependent Glycerol Transporter in HCT-15 CellsPrincipal Investigator
- Principal Investigator
  
  YUASA Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Molecular and Functional Characteristics of Glycerol Transporter in HCT-15 Cell ModelPrincipal Investigator
- Principal Investigator
  
  YUASA Hiroaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Effect of Probiotics on the absorption of drugs from the Small Intestine
- Principal Investigator
  
  HAYASHI Yayoi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kinjo Gakuin University
Novel Transporter Responsible for Intestinal Glycerol Absorption : Characterization of Its Function and Physiological RolePrincipal Investigator
- Principal Investigator
  
  YUASA Hiroaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Pharmacokinetic and Cellular Biological Study on Colonic Absorption : Strategies for Optimized Controlled Release Oral Drug DeliveryPrincipal Investigator
- Principal Investigator
  
  YUASA Hiroaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Nagoya City University
Quantitative and Molecular Mechanism-Based Analysis of Factors Interfering with Macromolecular Drug Targeting
- Principal Investigator
  
  HAYASHI Yayoi, 渡辺淳
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagoya City University
Study on Pharmacokinetics of Bioactive Macromolecular Drug for DDS : Scavenger Receptor-Mediated Internarization and Release of Fractionated [^3H] Heparin
- Principal Investigator
  
  WATANABE Jun
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagoya City University
経口薬物吸収の生理機構論的解析Principal Investigator
- Principal Investigator
  
  湯浅博昭
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagoya City University
Investigation on New Material for DDS : Study on the Mechanisms of Release of Mucopolysaccharide from Liver in Rats
- Principal Investigator
  
  WATANABE Jun
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagoya City University
Pharmacokinetic Study on Mucopolysaccharide : Effect of Plasma Protein on the Hepatic Uptake of fractionated Heparin
- Principal Investigator
  
  WATANABE Jun
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagoya City University

[Journal Article] Involvement of Proton-Coupled SLC49A4-Mediated Transport in the Export of Lysosomally Trapped Pyrilamine2024
- Author(s)
  Akino Shogo, Yasujima Tomoya, Shibutani Rei,Yamashiro Takahiro, Yuasa Hiroaki
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 52 Issue: 1 Pages: 19-25
- DOI
  10.1124/dmd.123.001354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21KK0280, KAKENHI-PROJECT-23K06283
[Journal Article] Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H<sup>+</sup>-driven lysosomal pyridoxine exporter2022
- Author(s)
  Akino Shogo, Yasujima Tomoya, Yamashiro Takahiro, Yuasa Hiroaki
- Journal Title
  
  Life Science Alliance
  
  Volume: 6 Issue: 2 Pages: e202201629-e202201629
- DOI
  10.26508/lsa.202201629
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0280, KAKENHI-PROJECT-20K07135, KAKENHI-PROJECT-21K15318
[Journal Article] Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter2022
- Author(s)
  Shinoda Yutaro、Yamashiro Takahiro、Hosooka Akira、Yasujima Tomoya、Yuasa Hiroaki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 43 Pages: 100443-100443
- DOI
  10.1016/j.dmpk.2021.100443
- NAID
  210000188785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07159
[Journal Article] Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2?Cells2020
- Author(s)
  Takenaka Risa、Yasujima Tomoya、Furukawa Junji、Hishikawa Yosuke、Yamashiro Takahiro、Ohta Kinya、Inoue Katsuhisa、Yuasa Hiroaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 8 Pages: 2622-2628
- DOI
  10.1016/j.xphs.2020.04.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07135
[Journal Article] pH-dependent pyridoxine transport by SLC19A2 and SLC19A3: Implications for absorption in acidic microclimates2020
- Author(s)
  Yamashiro Takahiro、Yasujima Tomoya、Said Hamid M.、Yuasa Hiroaki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 50 Pages: 16998-17008
- DOI
  10.1074/jbc.ra120.013610
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07135, KAKENHI-PROJECT-19K16416, KAKENHI-PROJECT-18KK0453
[Journal Article] Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells2020
- Author(s)
  Kabeya Tomoki、Mima Shinji、Imakura Yuki、Miyashita Toshihide、Ogura Izumi、Yamada Tadanori、Yasujima Tomoya、Yuasa Hiroaki、Iwao Takahiro、Matsunaga Tamihide
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 35 Issue: 4 Pages: 374-382
- DOI
  10.1016/j.dmpk.2020.04.334
- NAID
  50014558611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07135, KAKENHI-PROJECT-19H03391
[Journal Article] Functional Characteristics of Aquaporin 7 as a Facilitative Glycerol Carrier2014
- Author(s)
  Takahiro Katano, Yuko Ito, Kinya Ohta, Tomoya Yasujima, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 29 Issue: 3 Pages: 244-248
- DOI
  10.2133/dmpk.DMPK-13-RG-121
- NAID
  130004463384
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460194
[Journal Article] Competitive Inhibition of AQP7-mediated Glycerol Transport by Glycerol Derivatives2014
- Author(s)
  Takahiro Katano, Yuko Ito, Kinya Ohta, Tomoya Yasujima, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 29 Issue: 4 Pages: 348-351
- DOI
  10.2133/dmpk.DMPK-13-NT-139
- NAID
  130004463387
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460194
[Journal Article] Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.2008
- Author(s)
  Yuriko Ohgusu, Kinya Ohta, Megumi Ishii, Takahiro Katano, Kimihiko Urano, Jun Watanabe, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Drug Metab.Pharmacokinet. 23
  
  Pages: 279-284
- NAID
  10021956401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590151
[Journal Article] Effect of Lactobacillus casei on the absorption of nifedipine from rat small intestine.2007
- Author(s)
  Ryuji Kato, Hiroaki Yuasa, Katsuhisa Inoue, Takahiro Iwao, Kazuhiko Tanaka, Kazuya Ooi, Yayoi Hayashi
- Journal Title
  
  Drug Metab. Pharmacokinet. 22(3)
  
  Pages: 9-102
- NAID
  10019923271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Journal Article] Effect of Lactobacillus casei on intestinal absorption of drugs after administration into the small intestinal loops in Rats2006
- Author(s)
  Yayoi Hayashi, Emiru Takeda, Shunsuke Kamigaso, Katsuhisa Inoue, Hiroaki Yuasa, Ryuji Kato, Kazuya Ooi
- Journal Title
  
  Jpn. J. Pharm. Sci. Technol. 66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Journal Article] Effect of Lactobacillus casei on gastrointestinal motility : intestinal disposition of[^3H]PEG-4000(non-absorbable marker).2005
- Author(s)
  Emiru Takeda, Yayoi Hayashi, Mai Hatakeyama, Katsuhisa Inoue, Hiroaki Yuasa, Kazuya Ooi, Ryuji Kato
- Journal Title
  
  Jpn. J. Pharm. Sci. Technol. 65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Journal Article] Dual functional characteristic of human aquaporin 10 for solute transport.
- Author(s)
  Megumi Ishii, Kinya Ohta, Takahiro Katano, Kimihiko Urano, Jun Watanabe, Aki Miyamoto, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Cell.Physiol.Biochem. in press
- NAID
  130004639733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] FLVCR1/2のコリン輸送機能解析：CHT1との比較2024
- Author(s)
  山﨑美音, 廣瀬　舞, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06258
[Presentation] 各種細胞株でのコリン取込におけるFLVCR1/2の寄与の評価2024
- Author(s)
  保嶋智也, 川本彩果, 山城貴弘, 湯浅博昭
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06258
[Presentation] SLC19A2/3の蛍光性試験基質としてのamilorideの輸送特性の評価と利用2023
- Author(s)
  松井快人、山本道弘、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-23K06283
[Presentation] OAT2/SLC22A7の尿酸輸送機能の動物種差に関わる分子機構2023
- Author(s)
  澁谷玲衣、谷内夏月、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Analysis of the transport function of SLC19A2/3 for amiloride: utilization as a fluorescent probe substrate2023
- Author(s)
  Kaito Matsui, Michihiro Yamamoto, Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  2023 International Joint Meeting of 23rd ICCP450/38th JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06283
[Presentation] ENBT1/SLC43A3によるオロト酸輸送：HEK293細胞一過性発現系及びHepG2細胞での解析2023
- Author(s)
  森本遥香, 髙見華奈, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07159
[Presentation] Comparative evaluation of the choline transport functions of novel choline transporters and choline transporter 12023
- Author(s)
  Mai Hirose, Chitaka Namba, Yosuke Azuma, Tomoya Yasujima, Takahiro Yamashiro, Hiroaki Yuasa
- Organizer
  2023 International Joint Meeting of 23rd ICCP450/38th JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06258
[Presentation] SUBSTRATE-DEPENDENT CHARACTERISTICS IN THE TRANSPORT FUNCTION OF SLC19A3: EXAMINATION OF THE ASPECT OF ITS SENSITIVITY TO FLAVONOIDS2023
- Author(s)
  Hiroaki Yuasa, Saena Yamashita, Takahiro Yamashiro, Tomoya Yasujima
- Organizer
  25th North American ISSX Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06283
[Presentation] Functional characteristics and role of DIRC2/SLC49A4 as a novel lysosomal pyridoxine exporter2022
- Author(s)
  秋野翔伍、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] OAT2の尿酸輸送機能の動物種差2022
- Author(s)
  谷内夏月、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] OCT2阻害活性評価における基質依存的な差異：atenolol輸送阻害とMPP+輸送阻害との比較2022
- Author(s)
  細岡晶、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ENT類による核酸塩基取込における核酸塩基代謝酵素類の基質特異的協働効果2022
- Author(s)
  小西拓実、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ENBT1のオロト酸輸送機能2022
- Author(s)
  高見華奈, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07159
[Presentation] fisetinに対するCNT2の感受性の動物種差に関わるアミノ酸残基2022
- Author(s)
  田中雄大、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] DIRC2のpyrilamine輸送機能及び薬物動態的役割2022
- Author(s)
  秋野翔伍、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] 小腸に発現する新規コリントランスポーターの機能解析2022
- Author(s)
  東洋輔、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] オロト酸トランスポーターとしてのSMCT2の機能的同定2022
- Author(s)
  篠田裕太郎、細岡晶、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差に関わるヒト特異的アミノ酸残基2022
- Author(s)
  三宅浩平、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差に関わるアミノ酸残基2021
- Author(s)
  三宅浩平、高橋駿介、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] オロト酸トランスポーターとしてのヒトOAT10の機能的同定2021
- Author(s)
  篠田裕太郎, 細岡晶, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  第36回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-20K07159
[Presentation] OCT2における基質依存的な阻害活性差：atenolol輸送阻害試験とMPP+輸送阻害試験との比較2021
- Author(s)
  細岡晶、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] リソソーム膜局在型の新規pyridoxineトランスポーターの機能解析2021
- Author(s)
  秋野翔伍、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Functional identification of human OAT10 as an orotate transporter2021
- Author(s)
  篠田裕太郎、細岡晶、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] fisetin及び類縁フラボノイドに対するCNT2の感受性の動物種差2021
- Author(s)
  田中雄大、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ENT2の尿酸輸送機能の解析2021
- Author(s)
  間竹勇、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ENT2の尿酸輸送機能の解析：Caco-2細胞での検証2021
- Author(s)
  間竹勇、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A2/3のpyridoxine/thiamine輸送機構：輸送特性の基質間比較解析2021
- Author(s)
  山城貴弘、保嶋智也、Hamid M. Said、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Functional characterization of the carrier-mediated choline transport system in Caco-2 cells2021
- Author(s)
  難波知尭、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Comparative assessment of the uptakes of pyridoxine and thiamine in the rat small intestine: absence of Slc19a3-dependent function of carrier-mediated pyridoxine uptake2021
- Author(s)
  山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] BCRPの尿酸排出輸送活性の評価系としてのSNBT1/BCRP共発現細胞の利用：フラボノイド類の阻害効果2021
- Author(s)
  石牧礼子、奈良佳幸、保嶋智也、山城貴弘、太田欣哉、井上勝央、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ヒトCNT2及びCNT3に対するフラボノイド類の阻害作用の速度論的解析2021
- Author(s)
  難波知尭、矢嶋陽菜、黒田大祐、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] 核酸塩基類似薬物の腸管吸収機構：ヒトとラットとの比較2016
- Author(s)
  湯浅博昭，水野加奈子，保嶋智也，太田欣哉
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  岐阜
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Functional characterization of a novel nucleobase transporter: cooperation with salvage enzymes in cellular nucleobase utilization2014
- Author(s)
  Furukawa J, Inoue K, Ohta K and Yuasa H
- Organizer
  19th North American International Society for the Study of Xenobiotics / 29th Japanese Society for the Study of Xenobiotics Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] aquaporin 10の新たな機能としての核酸塩基輸送：HEK293細胞一過性発現系におけるuracil輸送の解析2014
- Author(s)
  伊藤悠子，太田欣哉，井上勝央，湯浅博昭
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] aquaporin 10の新たな機能としての核酸塩基輸送：HEK293細胞一過性発現系におけるuracil輸送の解析2014
- Author(s)
  伊藤悠子，太田欣哉，井上勝央，湯浅博昭
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] 新規促進拡散型核酸塩基トランスポーターの機能解析：核酸代謝酵素との機能的協働2014
- Author(s)
  古川純士、井上勝央、太田欣哉、湯浅博昭
- Organizer
  第9回トランスポーター研究会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] 核酸塩基利用における核酸塩基トランスポーターENBT1と核酸代謝酵素との協働的効果2014
- Author(s)
  古川純士、井上勝央、太田欣哉、湯浅博昭
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2014-11-20
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] 核酸塩基利用における新規核酸塩基トランスポーターと核酸代謝酵素の機能的協働効果2013
- Author(s)
  古川純士，井上勝央，太田欣哉，湯浅博昭
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] Molecular and Functional Identification of Novel Transporters2012
- Author(s)
  Katsuhisa Inoue and Hiroaki Yuasa
- Organizer
  27th The Japanese Society for the Study of Xenobiotics Annual Meeting
- Place of Presentation
  Chiba
- Invited
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] ヒトアクアポリン3のグリセロール輸送特性2010
- Author(s)
  宮本明希, 太田欣哉, 片野貴大, 浦野公彦, 渡辺淳, 井上勝央, 湯浅博昭
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  さいたま
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] ヒトアクアポリン3のglycerol輸送機構の双機能的特性2009
- Author(s)
  片野貴大, 杉本さや香, 浦野公彦, 宮本明希, 太田欣哉, 井上勝央, 渡辺淳, 湯浅博昭
- Organizer
  第55回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] ヒトアクアポリン10の物質輸送における双機能的特性2009
- Author(s)
  石井めぐみ, 太田欣哉, 片野貴大, 浦野公彦, 渡辺淳, 井上勝央, 湯浅博昭
- Organizer
  第24回日本薬物動態学会年会
- Place of Presentation
  京都
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] ヒトアクアポリン10の促進拡散型グリセロール輸送担体としての機能解析2008
- Author(s)
  石井めぐみ, 太田欣哉, 片野貴大, 浦野公彦, 渡辺淳, 井上勝央, 湯浅博昭
- Organizer
  第23回日本薬物動態学会年会
- Place of Presentation
  熊本
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] Effect of Lactobacillus casei on the absorption of nifedipine from rat small intestine.2006
- Author(s)
  Kato R., Hayashi Y., Takeda E., Iwao T., Tanaka K., Ooi K., Yuasa H.
- Organizer
  The 126 Annual Meeting of Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Presentation] Effect of Lactobacillus casei on the gastrointestinal absorption of nifedipine after oral administration in rats.2006
- Author(s)
  Hayashi Y., Kato R., Inoue K., Yuasa H.
- Organizer
  The 16 Annual Meeting of Japanese Society of Pharmaceutical Health Care and Sciences
- Place of Presentation
  Kanazawa
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Presentation] Effect of Lactobacillus casei strain Shirota on gastrointestinal motility in rats.2005
- Author(s)
  Takeda E., Hayashi, Y., Hatakeyama, M., Ooi, K., Kato, R., Inoue, K., Yuasa, H.
- Organizer
  13th NA ISSX/20th JSSX Meeting
- Place of Presentation
  Maui, Hawaii, U.S.A.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Presentation] Effect of Lactobacillus casei on gastrointestinal motility in rats.2005
- Author(s)
  Hayashi, Y., Takeda, E., Inoue, K., Yuasa, H., Ooi, K., Kato, R.
- Organizer
  US-Japan Conference on Drug Development and Rational Drug Design
- Place of Presentation
  Los Angeles, California, U.S.A.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Presentation] Effect of Lactobacillus casei on the uptake of some drugs into everted sacs in rats.2005
- Author(s)
  Mizuno, N., Hayashi, Y., Ooi, K., Kato, R., Inoue, K., Yuasa H., Kato R., Ooi K.
- Organizer
  Meeting of Tokai Branch, Pharmaceutical Society of Japan
- Place of Presentation
  Nagoya
- Year and Date
  2005-12-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Presentation] Effect of Lactobacillus casei on drug absorption : investigation by using the small intestinal loop tequnique in Rats.2005
- Author(s)
  Takeda E., Hayashi Y., Kamigaso S., Hatakeyama M., Inoue K., Yuasa H., Kato R., Ooi K.
- Organizer
  Meeting of Tokai Branch, Pharmaceutical Society of Japan
- Place of Presentation
  Nagoya
- Year and Date
  2005-12-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590151
[Presentation] Caco-2細胞におけるプリン型核酸塩基類の輸送の解析
- Author(s)
  田島健太郎, 水野加奈子, 太田欣哉, 湯浅博昭
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Caco-2細胞における5-fluorouracil輸送の解析
- Author(s)
  水野加奈子，太田欣哉，湯浅博昭
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  さいたま
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Carrier-mediated uptake of adenine in Caco-2 cells
- Author(s)
  Kentaro Tajima, Kanako Mizuno, Kinya Ohta, Hiroaki Yuasa
- Organizer
  19th NA ISSX/29th JSSX Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Caco-2細胞における6-mercaptopurine輸送の解析
- Author(s)
  水野加奈子, 田島健太郎, 太田欣哉, 湯浅博昭
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460194

1. INOUE KATSUHISA (50315892)

# of Collaborated Projects: 7 results

# of Collaborated Products: 20 results
2. HAYASHI Yayoi (00117847)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. Yasujima Tomoya (50753555)

# of Collaborated Projects: 5 results

# of Collaborated Products: 35 results
4. 山城貴弘 (20826614)

# of Collaborated Projects: 5 results

# of Collaborated Products: 36 results
5. OHTA Kinya (90448704)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
6. WATANABE Jun (80080175)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. HABA Masami (70254307)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 大澤匡弘 (80369173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YUASA HIROAKI 湯浅 博昭

Hiroaki Yuasa 湯浅 博昭

YUASA Hiroaki 湯浅 博昭

湯浅 博和 ユアサ ヒロアキ

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新規コリントランスポーター類の分子機能と生理的及び薬物動態的役割Principal Investigator

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Elucidation of the Function and Physiological Role of a Novel Polyamine TransporterPrincipal Investigator

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Nucleobase Transport Function of Aquaporin 10: Its Role in the Intestinal Absorption of Nucleobases and Analogous DrugsPrincipal Investigator

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Functional Characteristics of a Novel Transporter Specifically Expressed in the Endoplasmic Reticulum in Dendritic Cells and its Role in Immune SystemPrincipal Investigator

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Identification and Functional Analysis of the Na^+-Dependent Glycerol Transporter in HCT-15 CellsPrincipal Investigator

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Molecular and Functional Characteristics of Glycerol Transporter in HCT-15 Cell ModelPrincipal Investigator

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Novel Transporter Responsible for Intestinal Glycerol Absorption : Characterization of Its Function and Physiological RolePrincipal Investigator

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Pharmacokinetic and Cellular Biological Study on Colonic Absorption : Strategies for Optimized Controlled Release Oral Drug DeliveryPrincipal Investigator

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YUASA HIROAKI 湯浅博昭

Hiroaki Yuasa 湯浅博昭

YUASA Hiroaki 湯浅博昭

湯浅博和ユアサヒロアキ