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KIMOTO Hiroshi  木元 博史

ORCIDConnect your ORCID iD *help
Researcher Number 20225080
Affiliation (based on the past Project Information) *help 1993 – 1995: 国立予防衛生研究所, 免疫部, 研究員
1991: NIH, Dep. Cell. Immunol., Researcher, 細胞免疫部, 研究員
1991: 国立予防衛生研究所, 細胞免疫部, 研究官
Review Section/Research Field
Principal Investigator
Immunology
Except Principal Investigator
Immunology
Keywords
Principal Investigator
Abelsonマウス白血病ウィルス / 温度感受性変異株 / 胎児胸腺 / 幼若造血細胞 / 多能性分化能 / 単離精製 / マクロファ-ジ / マスト細胞 / B細胞分化 / μ鎖複合体 … More / λ5 / Vpre-B1 / T依存性抗原 / 遺伝子欠損マウス / 代替L鎖 / Vpre-B3欠損マウス / B細胞 / Vpre-B3 / Dμ蛋白 / 細胞分化 / T依存性免疫応答 / pre B細胞 / 遺伝子ターゲッティング / 分化 / 免疫応答 / FACS / 骨髄 / 脾臓 / B cell differentiation / mu chain complex / lambda 5 / Vper-B1 / T dependent antigen / gene targeting / surrogate loght chain / mice lacking Vpre-B3 (8HS-20) gene … More
Except Principal Investigator
細胞周期 / B細胞 / トランスジェニックマウス / CD43 / CD40 / VpreB-3 / 体細胞点変異 / 体細胞超変異 / 高親和性B細胞 / MAPキナーゼ / V_H gene replacement / circular DNA / 分化・成熟 / mu鎖代替L鎖複合体 / CD43レセプター / 遺伝子欠損マウス / Germinal Center(胚中心) / 記憶細胞 / 代替L鎖 / 胚中心B細胞 / V_H遺伝子 / error prone DNA repair / B7-2 / 幼若B細胞特異的遺伝子 / Ig gene superfamily / B細胞成熟 / μ鎖発現 / μ鎖輸送 / CD45R / Macー1陽性細胞 / シグナル伝達 / μ鎖複合体 / 前B細胞 / virgin B細胞 / B cell maturation / mu chain expression / B cell specific gene / surrogate L chains / lg gene super family / mu chain transport / B細胞生存維持 / 細胞周期調節 / CD43トランスジェニックマウス / 免疫反応 / IgM抗体産生 / IgG抗体産生 / B細胞dynamics / 細胞内相互作用 / CD43強発現マウス / IgMb抗体産生 / ホモ遺伝子強発現マウス / ターゲッティング / CD43ゲノム遺伝子 / Cre-loxPシステム / 細胞生存維持 / B cell survival / cell cycle regulation / CD43 transgenic mice / immune response / lgM antibodies / lgG antibodies / B cell dynamics / 一次濾胞B細胞 / 胚中心 / 細胞増殖 / 抗原提示機能 / 一次免疫反応 / centroblast / Bリンパ球 / centrocyte / 記憶Bリンパ球 / 免疫グロブリン遺伝子 / primary follicles / MAP kinase / TRAF / germinal center / cell cycle / somatic hypermutation / antigen presentation Less
  • Research Projects

    (8 results)
  • Co-Researchers

    (11 People)
  •  B細胞分化・成熟分子機構の解明及びその制御

    • Principal Investigator
      竹森 利忠
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  Mechanism of B cell maturaion

    • Principal Investigator
      TAKEMORI Toshitada
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health
  •  B細胞分化・成熟分子機構の解明およびその制御

    • Principal Investigator
      竹森 利忠
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  Functional role of CD43 in immune system

    • Principal Investigator
      NAGAOKA Hitoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health of Japan
  •  Analysis of mutant mice lacking Vpre-B3 (8HS-20) gene encoding a third surrogate light chair.Principal Investigator

    • Principal Investigator
      KIMOTO Hiroshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health ofJapan
  •  B細胞分化・成熟分子機構の解明およびその制御

    • Principal Investigator
      竹森 利忠
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  胎児胸腺由来幼若造血幹細胞の純化とその株化及びその多能性分化能の解析Principal Investigator

    • Principal Investigator
      木元 博史
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  The analysis of B cell differentiation and maturation

    • Principal Investigator
      TAKEMORI Toshitada
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health
  • 1.  TAKEMORI Toshitada (60114295)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  TOKUHISA Takeshi (20134364)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  NAGAOKA Hitoshi (20270647)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  MISAWA Yukiko (10250185)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KASIWADA Masaki (20270639)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  谷山 忠義 (20136609)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  横田 恭子 (20182701)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MIZUGUCHI Junichiro (20150188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OHNISHI Kazuo (90169011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  重本 和宏 (00192104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ADACHI Yoshihiro (20291122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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