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Kitamura Tsuneo  北村 庸雄

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KITAMURA Tsuneo  北村 庸雄

北村 庸雄  キタムラ ツネオ

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Researcher Number 20231285
Other IDs
External Links
Affiliation (Current) 2025: 順天堂大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2016 – 2019: 順天堂大学, 医学部, 先任准教授
2013 – 2015: 順天堂大学, 医学部, 准教授
2004: JUNTENDO UNIVERSITY, ASSOCIATE PROFESSOR, 医学部, 助教授
2003: 順天堂大学, 医学部, 講師
1996 – 2001: 順天堂大学, 医学部, 講師
1994 – 1995: 順天堂大学, 医学部, 助手
1991: 順天堂大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology
Except Principal Investigator
Gastroenterology
Keywords
Principal Investigator
肝再生 / 肝類洞内皮細胞 / アポトーシス / apoptosis / liver / 肝類洞再構築 / リゾホスファチジン酸 / リゾリン脂質 / オートタキシン / Calcium … More / Apoptosis / Syhingosine 1-Phosphate / Liver Sinusoidal Endothelial Cells / Alcoholic Liver Injury / 細胞内カルシウム / eNOS / Nitric Oxide / カルシウム / スフィンゴシン1-リン酸 / アルコール性肝障害 / SMP 30 / 肝細胞 / SMP30 / 老化 / sinusoidal endothelial cells / liver regeneration / 血流ストレス / hepatocyte / calcium signaling / 細胞内カルシウムイオン / シグナルトランスダクション / 癌 / 肝細胞増殖 / 肝類洞微小環境 / スフィンゴシン-1-リン酸 / スフィンゴシン-1-リン酸 / 肝類洞リモデリング … More
Except Principal Investigator
culture cell / wound healing / proliferation / migration / cytoskeleton / growth factor / gastric ulcer / 細胞骨格 / 受容体 / 細胞外基質 / 損傷修復モデル / 胃粘膜細胞 / culture cell 培養細胞 / wound healing 損傷性対 / proliferation 細胞増殖 / migration 細胞遊走 / cytoskeleton 細胞骨性 / growth factor 増殖因子 / gastric ulcer 男性度 / 培養細胞 / 創傷治療 / 細胞増殖 / 細胞遊走 / 増殖因子 / 胃潰瘍 / Ito cells / Ischeima-referfusion Injury / Oxygenation / Kupffer cells / Cytoskeleton / Preservation of Liver Graft / Microcirculation / Liver Transplantation / 臓器反射スペクトル法 / グラフト障害 / 白血球粘着 / 微小循環障害 / レーザー顕微鏡 / 酸素飽和度 / エンドセリン / 伊東細胞 / 再還流障害 / 組織酸素化 / Kupffer細胞 / 臓器保存 / 微小循環 / 肝移植 Less
  • Research Projects

    (8 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (15 People)
  •  Mechanisms of liver regeneration mediated by sinusoidal microcirculation in the regulation of autotaxin and lysophospholipidPrincipal Investigator

    • Principal Investigator
      Kitamura Tsuneo
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Mechanism of liver regeneration in regulation of sinusoidal remodeling through vascular nichPrincipal Investigator

    • Principal Investigator
      Kitamura Tsuneo
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  PROTECTIVE EFFECT OF SPHINGOSINE 1-PHOSPHATE ON LIVER SINUSOIDAL ENDOTHELIAL CELLS AGAINST ETHANOL-INDUCED APOPTOSISPrincipal Investigator

    • Principal Investigator
      KITAMURA Tsuneo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      JUNTENDO UNWARILY
  •  ROLE OF SENESCENCE MARKER PROTEIN-30 (SMP30) IN HEPATOCYTE APOPTOSISPrincipal Investigator

    • Principal Investigator
      KITAMURA Tsuneo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      JUNTENDO UNIVERSITY
  •  Role of Liver Sinusoidal Endothelial cell in Liver RegenerationPrincipal Investigator

    • Principal Investigator
      KITAMURA Tsuneo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  Signal Transdaction in Hepatocyte ProliferationPrincipal Investigator

    • Principal Investigator
      KITAMURA Tsuneo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine
  •  Molecular and cell biological investigation about the healing mechanism of gastric mucosal damage.

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine
  •  Developmental Research on Preservation of Liver Graft by Improving the Hepatic Microcirculation

    • Principal Investigator
      SATO Nobuhiro
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University School of Medicine

All 2019 2017 2016 2015 2005 2004 2003 Other

All Journal Article Book

  • [Book] Bile Acids and NAFLD/NASH. Bile Acid in Gastroenterology2017

    • Author(s)
      Kitamura T, Watanabe S
    • Total Pages
      11
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-25461011
  • [Book] Bile Acids and NAFLD/NASH. Bile Acid in Gastroenterology2017

    • Author(s)
      Kitamura T, Watanabe S
    • Total Pages
      11
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-16K09375
  • [Book] 慢性肝疾患における難治性そう痒症の治療の実際2017

    • Author(s)
      北村庸雄、髙森建二
    • Publisher
      医薬情報研究所
    • ISBN
    • Data Source
      KAKENHI-PROJECT-16K09375
  • [Book] Bile Acid in Gastroenterology: Basic and Clinical.2017

    • Author(s)
      Kitamura T, Watanabe S
    • Publisher
      Springer Japan
    • ISBN
    • Data Source
      KAKENHI-PROJECT-16K09375
  • [Book] Role of sphingosine 1-phosphate in protection of liver sinusoidal endothelial cells against ethanol-induced apoptosis. Microcirculation Annual 20052005

    • Author(s)
      Zheng D-M, Kitamura T, Ikejima K, Enomoto N, Yamashina S, Suzuki S, Takei Y, Sato N.
    • Publisher
      Asano M, oda M (eds), 21, NIHON-IGAKUKAN :
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Plasma Dynorphin A Concentration Reflects the Degree of Pruritus in Chronic Liver Disease: A Preliminary Report.2019

    • Author(s)
      Moniaga CS, Iwamoto S, Kitamura T, Fujishiro M, Takahashi N, Katsunari K, Ogawa H, Tominaga M, Takamori K.
    • Journal Title

      Acta Derm Venereol.

      Volume: 99 Issue: 4 Pages: 442-443

    • DOI

      10.2340/00015555-3139

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09375, KAKENHI-PROJECT-18F18410, KAKENHI-PROJECT-18K07396
  • [Journal Article] Gadoxetic Acid-Enhanced MR Imaging Predicts Simeprevir-Induced Hyperbilirubinemia During Hepatitis C Virus Treatment: A Pilot Study2016

    • Author(s)
      Okubo H, Kitamura T, Ando H, Fukada H, Igusa Y, Kokubu S, Miyazaki A, Fujimura A, Shiina S, Watanabe S
    • Journal Title

      J Clin Pharmacol

      Volume: 57 Issue: 3 Pages: 369-375

    • DOI

      10.1002/jcph.811

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461011, KAKENHI-PROJECT-16K09375, KAKENHI-PROJECT-16K10363
  • [Journal Article] 胆汁酸研究の進歩と展望. 痒みの発生機序2016

    • Author(s)
      北村庸雄、髙森建二
    • Journal Title

      肝・胆・膵

      Volume: 72 Pages: 877-891

    • Data Source
      KAKENHI-PROJECT-16K09375
  • [Journal Article] 胆汁酸研究の進歩と展望. 痒みの発生機序.2016

    • Author(s)
      北村庸雄、髙森建二
    • Journal Title

      肝・胆・膵

      Volume: 72 Pages: 877-891

    • Data Source
      KAKENHI-PROJECT-25461011
  • [Journal Article] Recessive Inheritance of Population-Specific Intronic LINE-1 Insertion Causes a Rotor Syndrome Phenotype2015

    • Author(s)
      Tatehiro Kagawa, Akira Oka, Yoshinao Kobayashi, Yoichi Hiasa, Tsuneo Kitamura, Hiroshi Sakugawa, Yukihiko Adachi, Kazuya Anzai, Kota Tsuruya, Yoshitaka Arase, Shunji Hirose, Koichi Shiraishi, Takashi Shiina, Tadayuki Sato, Ting Wang, Masayuki Tanaka, Hideki Hayashi et al.
    • Journal Title

      Human Mutation

      Volume: 36 Issue: 3 Pages: 327-332

    • DOI

      10.1002/humu.22745

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461011, KAKENHI-PROJECT-15K09785
  • [Journal Article] No contribution of the ABCB11 p.444A polymorphism in Japanese patients with drug-induced cholestasis.2015

    • Author(s)
      Kagawa T, Hirose S, Arase Y, Oka A, Anzai K, Tsuruya K, Shiraishi K, Orii R, Ieda S, Nakazawa T, Tomita K, Hokari R, Miura S, Ebinuma H, Saito H, Kitamura T, Horie Y, Okuse C, Wasada M, Inoko H, Tohkin M, Saito Y, Maekawa K, Takikawa H, Mine T
    • Journal Title

      Drug Metabolism and Disposition

      Volume: 43 Issue: 5 Pages: 691-697

    • DOI

      10.1124/dmd.114.061325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09031, KAKENHI-PROJECT-25461011
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, E nomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Biochem Biophys Res Conunun 323

      Pages: 1091-5

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004

    • Author(s)
      Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
    • Journal Title

      Biochem Biophys Res Commun 323

      Pages: 1091-1095

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut-derived endotoxin.2004

    • Author(s)
      Enomoto N, Takei Y, Yamashina S, Fukuda T, Suzuki S, Ikejima K, Kitamura T, Sato N.
    • Journal Title

      J Gastroentorol 39

      Pages: 1175-1181

    • NAID

      10014091735

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] The phosphodiesterase III inhibitor olprinone decreases sensitivity of rat Kupffer cells to endotoxin.2004

    • Author(s)
      Enomoto N, Takei Y, Hirose M, Ikejima K, Kitamura T, Sato N.
    • Journal Title

      Alcohol Clin Exp Res 28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Senescence marker protein-30 regulates Akt activity and contributes to cell survival in Hep G2 cells.2004

    • Author(s)
      Matsuyama S, Kitamura T, Enomoto N, Fujita T, Ishigami A, Handa S, Maruyama N, Zheng D, Ikej ima K, Takei Y, Sato N.
    • Journal Title

      Biochem Biophys Res Conunun 321

      Pages: 386-390

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut - derived endotoxin.2004

    • Author(s)
      Enomoto N, Takei Y, Yamashina S, Fukuda T, Suzuki S, Ikejima K, Kitamura T, Sato N.
    • Journal Title

      J Gastroentefol 39

      Pages: 1175-81

    • NAID

      10014091735

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Senescence marker protein-30 regulates Akt activity and contributes to cell survival in Hep G2 cells.2004

    • Author(s)
      Matsuyama S, Kitamura T, Enomoto N, Fujita T, Ishigami A, Handa S, Maruyama N, Zheng D, Ikejima K, Takei Y, Sato N.
    • Journal Title

      Biochem Biophys Res Commun 321

      Pages: 386-390

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] The phosphodiesterase III inhibitor olprinone decreases sensitivit y of rat Kupffer cells to endotoxin.2004

    • Author(s)
      Enomoto N, Takei Y, Hirose M, Ikejima K, Kitamura T, Sato N.
    • Journal Title

      Alcohol Clin Exp Res 28

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Prevention of Ethanol-Induced Liver Injury in Rats by an Agonist of PPAR{gamma}, Pioglitazone.2003

    • Author(s)
      Enomoto N, Takei Y, Hirose M, Konno A, Shibuya T, Matsuyama S, Suzuki S, Ikejima K, Kitamura T, Sato N
    • Journal Title

      J Pharmacol Exp Ther 306

      Pages: 846-854

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Prevention of Ethanol-Induced Liver Injury in Rats by an Agonist of PPAR {gamma}, Pioglitazone.2003

    • Author(s)
      Enomoto N, Takei Y, Hirose M, Konno A, Shibuya T, Matsuyama S, Suzuki S, Ikejima K, Kitamura T, Sato N.
    • Journal Title

      Pharmacol Exp Ther 306

      Pages: 846-854

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • [Journal Article] Role of sphingosine 1-phosphate in protection of liver sinusoidal endothelial cells against ethanol-induced apoptosis.

    • Author(s)
      Zheng D-M, Kitamura T, Ikejima K, Enomoto N, Yamashina S, Suzuki S, Takei Y, Sato N.
    • Journal Title

      Microcirculation Annual 2005 (Asano M, Oda M (eds))(NIHON-IGAKUKAN) 21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590689
  • 1.  SATO Nobuhiro (90028358)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  YOKOI Yukio (20150633)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  WATANABE Sumio (20138225)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HIROSE Miyoko (70266039)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  岩渕 和久 (10184897)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MIYAZAI Akihisa (20200149)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KITAMI Noriyuki (90053256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MAEHIRO Kohei (30238878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YAMAGUCHI Yasushi (70241015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ADACHI Hiroyasu (00245705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  FUJITA Toshiko (00100131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  IKEJIMA Kenichi (20317382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ENOMOTO Nobuyuki (20348973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 14.  TAKEI Yoshiyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  冨田 謙吾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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