OKA Yoshihiro 岡芳弘

Researcher Number	20273691
Other IDs
External Links
Affiliation (Current)	2023: 大阪大学, 大学院医学系研究科, 寄附講座教授
Affiliation (based on the past Project Information) *help	2017: 大阪大学, 医学系研究科, 寄附講座教授 2016: 大阪大学, 医学系研究科, 特任教授(常勤) 2015: 大阪大学, 医学(系)研究科(研究院), 招へい教授 2015: 大阪大学, 医学(系)研究科(研究院), 特任教授(常勤) 2013 – 2014: 大阪大学, 医学(系)研究科(研究院), 教授 … More 2013 – 2014: 大阪大学, 医学(系)研究科(研究院), 特任教授 2012: 大阪大学, 医学(系)研究科(研究院), 講師 2012: 大阪大学, 大学院・医学絵系研究科, 講師 2011: 大阪大学, 大学院・医学系研究科, 講師 2005 – 2011: 大阪大学, 医学系研究科, 講師 2009: 大阪大学, 大学院・医学系研究科, 講師 1999 – 2005: 大阪大学, 医学系研究科, 助手 1996 – 1998: Osaka Univ.Med.School, Dept.of Med.III,Assistant prof., 医学部, 助手 1988: Osaka University Hospital, 医学部附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Hematology / Biological Sciences Except Principal Investigator Hematology / Biological Sciences / Pediatrics / Immunology / Pathological medical chemistry / Risk sciences of radiation/Chemicals / Hematology
Keywords	Principal Investigator WT1 / 免疫療法 / 癌ワクチン / ペプチドワクチン / 癌免疫療法 / 肺癌 / 白血病 / leukemia / 癌抗原 / CTL … More / 癌免疫 / 癌免疫動態 / 胸腺腫瘍 / バイオマーカー / 胸腺悪性腫瘍 / 胸部悪性腫瘍 / cancer vaccine / cancer immunotherapy / ペプチド癌ワクチン / clinical trial / immunotherapy / 臨床試験 / G-CSF / MDS / 肺がん / がんワクチン / 胸部悪性疾患 / ヘルパー / ヘルパーペプチド / ヘルパーTリンパ球 / Th17 / T細胞レセプター / 悪性腫瘍 / 免疫治療 / 胸腺腫 / 急性白血病 / 抗腫瘍免疫療法 … More Except Principal Investigator WT1 / 白血病 / leukemia / WT1遺伝子 / 造血幹細胞 / oncogene / leukemogenesis / 免疫療法 / tumor suppressor gene / 骨髄移植 / WT1アッセイ / solid cancer / motility / Scid / NOD / Leukemia / minimal residual disease / 微小残存白血病 / 小児血液悪性腫瘍 / 同種造血幹細胞移植 / 癌ワクチン / Wilms' tumor gene / 臍帯血 / 骨髄異形成症候群 / ウイルムス腫瘍遺伝子 / Stat3 / 32D細胞 / apoptosis / 微小残存病変 / MRD / immunoglobulin heavy chain variable region genes / V_Hgene family / 免疫グロブリンH鎖 / 免疫グロブリン可変部領域遺伝子 / 免疫グロブリン遺伝子の再構成 / anti-apootosis / プロテオミクス / 発がん遺伝子 / 浸潤能 / 抗アポトーシス / 癌遺伝子 / anti-apoptosis / radioactive iodine / severe combined immuno-deficiency / functional damage / change in gene expression / mutation in human tissues / organ and tissue damage / mouse with human tissues / fission radionuclides / ヒト甲状腺ホルモン分泌能 / 放射線ヒト臓器・組織障害 / 放射線ヨード / 放射性ヨード / 重度複合免疫不全マウス / 機能異常 / 遺伝子発現異常(ジーンチップ) / ヒト組織遺伝子変異 / ヒト臓器・組織障害 / ヒト臓器・組織置換マウス / 核分裂放射能 / immunotherany / myelochisplastic syndrome / Wilm's tumor gene / single-cell RT-PCR / 32D / tumor marker / cell cycle / M / G2 / CD34 / ウィルムス腫瘍遺伝子 / oncogenic / 白血病腫瘍マーカー / bone marrow transplantation / キメラ遺伝子 / 微少残存腫瘍 / The WT1 gene / WWドメイン / アポトーシス / EX VIVO expantion, / Cord Blood, / Hematopoietic stem cell, / 可溶性IL-6受容体 / 造血前駆細胞 / 体外増幅 / hematopoietic stem cell / WT1 gene / 微小残存腫瘍 / hematopoietic progenitor cells / 32D cells / M期 / G_2 / がん遺伝子 / がん抑制遺伝子 / Wilms tumor gene / 小児血液腫瘍 / 免疫モニタリング / 同種移植後免疫療法 / 早期探索臨床試験 / 造血細胞移植 / がんワクチン / 同種造血細胞移植 / がん免疫 / ペプチドワクチン / 同種造血細胞移植後 / 小児がん / WT1ペプチドワクチン / 小児腫瘍学 / 免疫学 / 癌 / 遺伝子 / 免役療法 / 分子標的治療法 / 分子標的治療 / 分子標的療法 / 分子診断 / 遺伝子診断 / 支持細胞 / 異種移植 / WT1結合タンパク / 顆粒球系コロニー / G-CSF / MDS / AML / signal transduction / Leukemogenesis / real time PCR / WT1 assay / ドナーリンパ球輸注 / 化学療法 / 微少残存病変 Less

Analysis of immune response against cancer, which may lead to establishment of WT1 peptide-based immunotherapy for the conventional treatment-resistant malignancies in the respiratory medicine fieldPrincipal Investigator
- Principal Investigator
  
  OKA YOSHIHIRO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Elucidation and control of molecular mechanism in WT1 peptide vaccine therapy after allogeneic hematopoietic stem cell transplantation
- Principal Investigator
  
  Hashii Yoshiko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Development of WT1 peptide-based immunotherapy for inoperable thoracic malignant tumors, and analysis of immunodynamics of the novel therapyPrincipal Investigator
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Development of WT1 based immunotherapy after stem cell transplantation and the analysis of antitumor activity
- Principal Investigator
  
  HASHII Yoshiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Cancer antigen WT1-targeting peptide vaccine therapy for lung cancerPrincipal Investigator
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Development of WT1 peptide cancer vaccine targeting lung cancerPrincipal Investigator
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Development of molecular diagnosis and molecule-targeted therapy for leukemia
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
The function of the Wilms' tumor gene (WT1) overexpressed in leukemia and solid cancers
- Principal Investigator
  
  OJI Yusuke
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Development and analysis of human organ/tissue damage by fission radionuclides
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Osaka University
WT1 protein-targeted immunotherapy for leulemia
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
WT1アッセイを用いた、白血病及び類縁疾患の遺伝子診断
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Development of cancer immunotherapy targeting WT1 which highly expresses in patients with hematopoictic maliganacies including leukemia.Principal Investigator
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Role of the Wilms' tumor gene WT1 in human leukemogenesis
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
肺癌に対する、WT1を標的とした癌ワクチンの開発Principal Investigator
- Principal Investigator
  
  岡芳弘
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Immunotherapy against leukemia targeting WT1 productPrincipal Investigator
- Principal Investigator
  
  OKA Yoshihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
白血病の原因遺伝子ろしてのWT1遺伝子の分子生物学的機能の解析
- Principal Investigator
  
  小川啓恭
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
転写因子WT1の造血幹細胞の増殖,分化の制御に果たす役割の解析
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
性差による競合的ヒト/マウス異種移植実験系を用いた人造血幹細胞の動態解析
- Principal Investigator
  
  相馬俊裕
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
The role of the tumor suppressor gene WT1 in human leukemogenesis.
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Individualized therapy of patients with leukemia based on WT1 assay.
- Principal Investigator
  
  HIROYASU Ogawa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
白血病の遺伝子診断と白血病治療の個別化
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
白血病の原因遺伝子としてのWT1遺伝子の分子生物学的機能の解析
- Principal Investigator
  
  小川啓恭
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
転写因子WT1の造血幹細胞の増殖、分化の制御に果たす役割の解析
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
急性白血病細胞および未熟造血細胞の増殖、分化におけるWT1の生物学的役割の解析Principal Investigator
- Principal Investigator
  
  岡芳弘
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
微小残存白血病細胞の新しい検出法の確立による白血病の個性化した治療法の開発
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Analysis of roles of tumor suppressor gene WT1 in human leukemogenesis.
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Wilms tumor gene(WT1)expression in leukemic and normal hematopoietic stem cells.
- Principal Investigator
  
  OGAWA Hiroyasu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
DEVELOPMENT OF QUANTITATIVE ASSAY SYSTEM OF HUMAN HEMATOPOIETIC STEM CELL USING NOD/SCID MOUSE AND STROMA CELL LINE MS5
- Principal Investigator
  
  SOMA Toshihiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
微少残存白血病細胞の新しい検出法の確立による白血病の新しい治療法の開発
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
急性白血病に対する、核内タンパクWT1を標的にした抗腫瘍免疫療法Principal Investigator
- Principal Investigator
  
  岡芳弘
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Role of the tumor suppressor gene WT1 in human leukemogenesis.
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Analysis of the mechanisms of V_H gene selection in theformation of immunoglovulin heavy chain variable region genes.
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University Medical School

[Book] Immunotherapy of Cancer (Chapter 12 ) WT1 Peptide Vaccine for the Treatment of Malignancies: Its Development, Recent Progress, and Future Perspectives2016
- Author(s)
  Oka Y, Tsuboi A, Nakajima H, Fujiki F, Nishida S, Morimoto S, Nakata J. Nakae Y, Takashima S, Tatsumi N, Hosen N, Oji Y, Sugiyama H.
- Total Pages
  27
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K09173
[Journal Article] Combination Gemcitabine and WT1 Peptide Vaccination Improves Progression-Free Survival in Advanced Pancreatic Ductal Adenocarcinoma: A Phase II Randomized Study.2018
- Author(s)
  Nishida S, Ishikawa T, Egawa S, Koido S, Yanagimoto H, Ishii J, Kanno Y, Kokura S, Yasuda H, Oba MS, Sato M, Morimoto S, Fujiki F, Eguchi H, Nagano H, Kumanogoh A, Unno M, Kon M, Shimada H, Ito K, Homma S, Oka Y, Morita S, Sugiyama H.
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 6 Issue: 3 Pages: 320-331
- DOI
  10.1158/2326-6066.cir-17-0386
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11136, KAKENHI-PROJECT-17K07215, KAKENHI-PROJECT-17K07216, KAKENHI-PROJECT-15K09050, KAKENHI-PROJECT-15K09173
[Journal Article] WT1 peptide-based immunotherapy for advanced thymic epithelial malignancies2018
- Author(s)
  Oji Y、Inoue M、Takeda Y、Hosen N、Shintani Y、Kawakami M、Harada T、Murakami Y、Iwai M、Fukuda M、Nishida S、Nakata J、Nakae Y、Takashima S、Shirakata T、Nakajima H、Hasegawa K、Kida H、Kijima T、Morimoto S、Fujiki F、Tsuboi A、Morii E、Morita S、Sakamoto J、Kumanogoh A、Oka Y、Okumura M、Sugiyama H
- Journal Title
  
  International Journal of Cancer
  
  Volume: 142 Issue: 11 Pages: 2375-2382
- DOI
  10.1002/ijc.31253
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-16K11136, KAKENHI-PROJECT-17K07215, KAKENHI-PROJECT-17K07216, KAKENHI-PROJECT-15K09173, KAKENHI-PROJECT-15K09476
[Journal Article] Wilms’ tumor gene 1 (WT1) peptide vaccine therapy for hematological malignancies: from CTL epitope identification to recent progress in the clinical studies including a cure-oriented strategy.2017
- Author(s)
  Oka Y., Tsuboi A., Nakata J., Nishida S., Hosen N., Kumanogoh A., Oji Y., Sugiyama H.
- Journal Title
  
  Oncol Res Treat.
  
  Volume: 40 Issue: 11 Pages: 682-690
- DOI
  10.1159/000481353
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11136, KAKENHI-PROJECT-15K09173
[Journal Article] Wilms tumour 1 peptide vaccine as a cure-oriented post-chemotherapy strategy for patients with acute myeloid leukaemia at high risk of relapse.2017
- Author(s)
  Nakata J, Nakae Y, Kawakami M, Morimoto S, Motooka D, Hosen N, Fujiki F, Nakajima H, Hasegawa K, Nishida S, Tsuboi A, Oji Y, Oka Y, Kumanogoh A, Sugiyama H.
- Journal Title
  
  Br J Haematol.
  
  Volume: XX Issue: 2 Pages: 287-290
- DOI
  10.1111/bjh.14768
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11136, KAKENHI-PROJECT-17K07216, KAKENHI-PROJECT-15K09173, KAKENHI-PROJECT-15K09476, KAKENHI-PROJECT-15K19550
[Journal Article] Syndecan-4 as a biomarker to predict clinical outcome for glioblastoma multiforme treated with WT1 peptide vaccine2016
- Author(s)
  Takashima S, Oka Y, Fujiki F, Morimoto S, Nakajima H, Nakae Y, Nakata J, Nishida S, Hosen N, Tatsumi N, Mizuguchi K, Hashimoto N, Oji Y, Tsuboi A, Kumanogoh A, Sugiyama H
- Journal Title
  
  Future Sci OA
  
  Volume: FSO96 Issue: 4 Pages: FSO96-FSO96
- DOI
  10.4155/fsoa-2015-0008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430162, KAKENHI-PROJECT-15K18446, KAKENHI-PROJECT-15K09173, KAKENHI-PROJECT-15K19550
[Journal Article] Association of WT1 IgG antibody against WT1 peptide with prolonged survival in glioblastoma multiforme patients vaccinated with WT1 peptide.2016
- Author(s)
  Oji Y, Hashimoto N, Tsuboi A, Murakami Y, Iwai M, Kagawa N, Chiba Y, Izumoto S, Elisseeva O, Ichinohasama R, Sakamoto J, Morita S, Nakajima H, Takashima S, Nakae Y, Nakata J, Kawakami M, Nishida S, Hosen N, Fujiki F, Morimoto S, Adachi M, Iwamoto M, Oka Y, Yoshimine T, Sugiyama H.
- Journal Title
  
  Int J Cancer.
  
  Volume: 139 Issue: 6 Pages: 1391-401
- DOI
  10.1002/ijc.30182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462257, KAKENHI-PROJECT-26430162, KAKENHI-PROJECT-26462195, KAKENHI-PROJECT-15K18446, KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-15K09173, KAKENHI-PROJECT-15K09476, KAKENHI-PROJECT-15K10331, KAKENHI-PROJECT-16K11136, KAKENHI-PROJECT-15K19550
[Journal Article] Feasibility of cancer immunotherapy with WT1 peptide vaccination for solid and hematological malignancies in children2016
- Author(s)
  Sawada A, Inoue M, Kondo O, Yamada-Nakata K, Ishihara T, Kuwae Y, Nishikawa M, Ammori Y, Tsuboi A, Oji Y, Koyama-Sato M, Oka Y, Yasui M, Sugiyama H, Kawa K
- Journal Title
  
  Pediatric Blood ＆Ｃancer
  
  Volume: 63 Issue: 2 Pages: 234-241
- DOI
  10.1002/pbc.25792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09173
[Journal Article] An essential role of the avidity of T-cell receptor in differentiation of self-antigen-reactive CD8+ T cells2016
- Author(s)
  Kondo K, Fujiki F, Nakajima H, Yatsukawa E, Morimoto S, Tatsumi N, Nishida S, Nakata J, Oka Y, Tsuboi A, Hosen N, Oji Y, Sugiyama H
- Journal Title
  
  Journal of Immunotherapy
  
  Volume: 39 Issue: 3 Pages: 127-139
- DOI
  10.1097/cji.0000000000000114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09173, KAKENHI-PROJECT-26430162, KAKENHI-PROJECT-15K18446, KAKENHI-PROJECT-15K19550, KAKENHI-PROJECT-25460685
[Journal Article] Transduction of a novel HLA-DRB1*04:05-restricted, WT1-specific TCR gene into human CD4+T cells confers killing activity against human leukemia cells2015
- Author(s)
  Katsuhara A., Fujiki F., Aoyama N., Tanii S., Morimoto S., Oka Y., Tsuboi A., Nakajima H., Kondo K., Tatsumi N., Nakata J., Nakae Y., Takashima S., Nishida S., Hosen N., Sogo S., Oji Y., Sugiyama H.
- Journal Title
  
  Anticancer Research
  
  Volume: 35 Pages: 1251-1262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591164
[Journal Article] Two distinct effector memory cell populations of WT1 (Wilms' tumor gene 1)-specific cytotoxic T lymphocytes in acute myeloid leukemia patients2015
- Author(s)
  Nakae Y., Oka Y., Fujiki F., Morimoto S., Kamiya T., Takashima S., Nakata J., Nishida S., Nakajima H., Hosen N., Tsuboi A, Kyo T., Oji Y., Mizuguchi K., Kumanogoh A., Sugiyama H.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: in press Issue: 7 Pages: 791-804
- DOI
  10.1007/s00262-015-1683-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591164, KAKENHI-PROJECT-25830116, KAKENHI-PROJECT-26430162, KAKENHI-PROJECT-15K19550
[Journal Article] A vaccine for leukemia: one step closer? Cure-oriented WT1 peptide vaccination therapy is being developed2013
- Author(s)
  Oka Y.
- Journal Title
  
  Clinical Investigation
  
  Volume: 3 Issue: 5 Pages: 421-424
- DOI
  10.4155/cli.13.27
- Data Source
  KAKENHI-PROJECT-24591164
[Journal Article] Identification of a Wilms' tumor 1 (WT1)-derived immunogenic CD4+ T-cell epitope that is recognized in the context of common Caucasian HLA-DR haplotypes2013
- Author(s)
  Anguille S., Fujiki F., Smits E.L., Oji Y., Lion E., Oka Y., Berneman Z.N., Sugiyama H.
- Journal Title
  
  Leukemia
  
  Volume: 27 Pages: 748-750
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] WT1 peptide immunotherapy for gynecologic malignancies resistant to conventional therapies: a phase II trial2013
- Author(s)
  Miyatake T., Ueda Y., Morimoto A., Enomoto T., Nishida S., Shirakata T., Oka Y., Tsuboi A., Oji Y., Hosen N., Nakatsuka S-I., Morita S., Sakamoto J., Sugiyama H., Kimura T.
- Journal Title
  
  Jounal of Cancer Research and Clinical Oncology
  
  Volume: 139 Pages: 457-463
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] WT1 peptide vaccination following allogeneic stem cell transplantation in pediatric leukemic patients with high risk for relapse: successful maintenance of durable remission2012
- Author(s)
  Hashii Y, Sato-Miyashita E, Matsumura R, Kusuki S, Yoshida H, Ohta H, Hosen N, Tsuboi A, Oji Y, Oka Y, Sugiyama H, Ozono K
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 530-532
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients2012
- Author(s)
  Hosen N., Matsuoka Y, Kishida S., Nakata J., Mizutani Y., Hasegawa K., Mugitani A., Ichihara H., Aoyama Y., Nishida S., Tsuboi A., Fujiki F., Tatsumi N., Nakajima H., Hino M., Kimura T., Yata K., Abe M., OkaY., Oji Y., Kumanogoh A., Sugiyama H
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 2135-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] Vaccination with the WT-1 (Wilms’ tumor gene-1) peptide and the BCG-CWS in melanoma: A case report.2012
- Author(s)
  Nishioka M. et al.
- Journal Title
  
  European Journal of Dermatology
  
  Volume: 22 Issue: 2 Pages: 258-259
- DOI
  10.1684/ejd.2011.1619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591164
[Journal Article] Long-term WT1 peptide vaccination for patients with minimal residual disease2012
- Author(s)
  Tsuboi A., Oka Y., Kyo T., Katayama Y., Elisseeva O.A., Kawakami M., Nishida S., Morimoto S., Murao A., Nakajima H., Hosen N., Oji Y
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 1410-1413
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] Biased usage of T cell receptorβ-chain variable region genes of WT1(Wilms' tumor gene)-specific CD8^+ T cells in patients with solid tumors and healthy donors2012
- Author(s)
  Morimoto S., Oka Y., Tsuboi A., Tanaka Y., Fujiki F., Nakajima H., Hosen N., Nishida S., Nakata J., Nakae Y., Murao A., Myoui A., Enomoto T., Izumoto S., Sekimoto M., Kagawa N., Hashimoto N., Yoshimine T., Oji Y., Kumanogoh A., Sugiyama H
- Journal Title
  
  Cancer Science
  
  Volume: 103 Pages: 408-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] Enhanced tumor immunity of WT1 peptide vaccination by interferon-βadministration2012
- Author(s)
  Nakajima H., Oka Y., Tsuboi A., Tatsumi N., Yamamoto Y., Fujiki F., Li Z., Murao A., Morimoto S., Hosen N., Shirakata T., Nishida S., Kawase I., Isaka Y., Oji Y., Sugiyama H
- Journal Title
  
  Vaccine
  
  Volume: 30 Pages: 722-729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] A vaccine for leukemia -one step closer? Cure-oriented WT1 peptide vaccination therapy is being developed2012
- Author(s)
  Oka Y
- Journal Title
  
  (Editorial) Clinical Investigation
  
  Volume: 3 Pages: 421-424
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] 同種造血幹細胞移植後の難治性小児血液腫瘍患者におけるWT1ペプチドワクチンを用いた免疫療法2011
- Author(s)
  橋井佳子、松村梨沙、吉田寿雄、宮下恵実子、太田秀明、坪井昭博、尾路祐介、保仙直毅、岡芳弘、大薗恵一、杉山治夫
- Journal Title
  
  Biotherapy
  
  Volume: 25 Pages: 851-856
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] 悪性腫瘍に対するWT1ペプチドワクチン療法-特に2011
- Author(s)
  Oka Y, Tsuboi A, Nishida S, Hosen N, Nakata J, Hashii Y, Maeda T, Oji Y, Kumanogoh A, Sugiyama H
- Journal Title
  
  造血器腫瘍に焦点を当て
  
  Volume: 52 Pages: 235-242
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow (BM) in tumor-bearing patients: an important role of BM as a secondary lymphoid organ.2010
- Author(s)
  Murao A, Oka Y, Tsuboi A, Elisseeva OA, Harada Y, Fujiki F, Nakajima H, Nishida S, Hosen N, Shirakata T, Hashimoto N, Myoui A, Ueda T, Takeda Y, Osaki T, Enomoto T, Yoshikawa H, Kimura T, Oji Y, Kawase I, Sugiyama H.
- Journal Title
  
  Cancer Science (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination.2010
- Author(s)
  Van Tendeloo V.F., Oka Y., et al
- Journal Title
  
  Proceedings of the National Academy of Sciences of the USA
  
  Volume: 107 Pages: 13824-13829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] Prognostic Significance of WT1 mRNA and anti-WT1 Antibody Levels in Peripheral Blood in Patients with Myelodysplastic Syndromes.2010
- Author(s)
  Tamura H, Dan K, Yokose N, Iwakiri R, Ohta M, Sakamaki H, Tohyama K, Kondo A, Hyodo H, Nakamura K, Yamashita T, Elisseeva O. A, Oka Y, Oji Y, Sugiyama H, Ogata K.
- Journal Title
  
  Leukemia Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Biased usage of BV gene families of T cell receptors of WT1 (Wilms' tumor gene)-specific CD8+ T cells in patients with myeloid malignancies2010
- Author(s)
  Tanaka-Harada Y., Kawakami M., Oka Y., Tsuboi A., Katagiri T., Elisseeva O.A., Nishida S., Shirakata T., Hosen H., Fujiki F., Murao N., Nakajima H., Oji Y., Kanda Y., Kawase I., Sugiyama H
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 594-600
- NAID
  10026589035
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination2010
- Author(s)
  Van Tendeloo V.F., Van de Velde A., Van Driessche A., Cools N., Anguille S., Price D.A., Vermeulen K., Pieters K., Nijs G., Stein B., Smits E.L., Schroyens W.A., Gadisseur A. P., Vrelust I., Jorens P.G., Goossens H., de Vries I.J., Oji Y., Oka Y., Sugiyam
- Journal Title
  
  Proceedings of the National Academy of Sciences of the USA(PNAS)
  
  Volume: 107 Pages: 13824-13829
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] Biased usage of BV gene families of T cell receptors of WT1 (Wilms' tumor gene)-specific CD8+ T cells in patients with myeloid malignancies2010
- Author(s)
  Tanaka-Harada Y, Kawakami M, Oka Y, Tsuboi A, Katagiri T, Elisseeva O, Nishida S, Shirakata T, Hosen N, Fujiki F, Murao A, Nakajima H, Oji Y, Kanda Y, Kawase I, Sugiyama H.
- Journal Title
  
  Cancer Science 101
  
  Pages: 594-600
- NAID
  10026589035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Prognostic significance of WT1 mRNA and anti-WT1 antibody levels inperipheral blood in patients with myelodysplastic syndromes.2010
- Author(s)
  Tamura H., Oka Y., et al.
- Journal Title
  
  Leukemia Research
  
  Volume: 34 Pages: 986-990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] Sensitive immunohistochemical detection of WT1 protein in tumors with anti-WT1 antibody against WT1 235 peptide.2010
- Author(s)
  Ichinohazama R., Oka Y., et al.
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 1089-1092
- NAID
  10026591723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 Peptide Immunotherapy for Cancer in Children and Young Adults2010
- Author(s)
  Yo shi ko Ha shi i, Emiko Sato, Hideaki Ohta, Yoshihiro Oka, Haruo Sugiyama, keiichi Osono.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 55 Pages: 352-355
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] Effects of concomitant temozolomide and radiation therapies on WT1-specific T cells in malignant glioma.2010
- Author(s)
  Chiba Y., Oka Y., et al.
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 40 Pages: 395-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 peptide immunotherapy for cancer in children and young adults2010
- Author(s)
  Hshii Y., Oka Y., et al.
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 55 Pages: 352-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] A clear correlation between WT1-specific Th response and clinical response in WT1 CTL epitope vaccination2010
- Author(s)
  Fujiki F., Oka Y., Kawakatsu M., Tsuboi A., Harada Y., Hosen N., Nishida S., Shirakata T., Nakajima H., Tatsumi N., Hashimoto N., Taguchi T., Ueda S., Nonomura N., Takeda Y., Ito T., Myoui A., Izumoto Izumoto S., Maruno M., Yoshimine T., Noguchi S., Okuyama A., Kawase I., Oji Y., Sugiyama H
- Journal Title
  
  Anticancer Research
  
  Volume: 30 Pages: 2247-2254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1ペプチドがんワクチン2010
- Author(s)
  岡芳弘、坪井昭博, ら
- Journal Title
  
  細胞
  
  Volume: 42 Pages: 480-483
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] Prognostic value of WT1 protein expression level and MIB-1 staining index as predictor of response to WT1 immunotherapy in glioblastoma patients.2010
- Author(s)
  Chiba Y., Oka Y., et al.
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 27 Pages: 29-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 peptide vaccination in combination with imatinib therapy for apatient with CML in the chronic phase.2010
- Author(s)
  Narita M., Oka Y., et al.
- Journal Title
  
  International Journal of Medical Sciences
  
  Volume: 7 Pages: 72-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] A clear correlation between WT1-specific Th response and clinical response in WT1 CTL epitope vaccination.2010
- Author(s)
  Fujiki F., Oka Y., Kawakatsu M., Tsuboi A., Harada Y., Hosen N., Nishida S., Shirakata T., Nakajima H., Tatsumi N., Hashimoto N., Taguchi T., Ueda S., Nonomura N., takeda Y., Ito T., Myoui A., Izumoto Izumoto S., Maruno M., Yoshimine T., Noguchi S., Okuya
- Journal Title
  
  Anticancer Research
  
  Volume: 30 Pages: 2247-2254
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] Prognostic significance of WT1 mRNA and anti-WT1 antibody levels in peripheral blood in patients with myelodysplastic syndromes.2010
- Author(s)
  Tamura H., Dan K., Yokose N., Iwakiri R., Ohta M., Sakamaki H., Ohyama K., Kondo A., Hyodo H., Nakamura K., Yamashita T., Elisseeva O. A., Oka Y., Oji Y., Sugiyama H., Ogata K
- Journal Title
  
  Leukemia Research
  
  Volume: 34 Pages: 986-990
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow (BM) in tumor-bearing patients: an important role of BM as a secondary lymphoid organ2010
- Author(s)
  Murao A., Oka Y., Tsuboi A., Elisseeva O.A., Harada Y., Fujiki F., Nakajima H., Nishida S., Hosen N., Shirakata T., Hashimoto N., Myoui A., Ueda T., Takeda Y., Osaki T., Enomoto T., Yoshikawa H., Kimura T., Oji Y., Kawase I., Sugiyama H
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 848-854
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] WT1 vaccine induces reduction in minimal residual disease in an imatinib-treated CML patient2010
- Author(s)
  Oji Y., Oka Y., Nishida S., Tsuboi A., Kawakami M., Shirakata T., Takahashi K., Murao A., Nakajima H., Narita M., Takahashi M., Morita S., Sakamoto J., Tanaka T., Kawase I., Hosen N., Sugiyama H.
- Journal Title
  
  European Journal of Hematology
  
  Volume: 85 Pages: 358-360
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] WT1 peptide vaccine, one of the most promising cancer vaccines : its present status and the future prospects.2010
- Author(s)
  Oka Y., Sugiyama H.
- Journal Title
  
  Immunotherapy
  
  Volume: 2 Pages: 591-594
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow in tumor-bearing patients : an important role of bone marrow as a secondary lymphoid organ.2010
- Author(s)
  Murao A., Oka Y., et al.
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 848-854
- NAID
  10026590478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 peptide vaccination in combination with imatinib therapy for a patient with CML in the chronic phase2010
- Author(s)
  Narita M., Masuko M., Kurasaki T., Kitajima T., Takenouchi S., Saitoh A., Watanabe N., Furukawa T., Toba K., Fuse I., Aizawa I., Kawakami M., Oka Y., Sugiyama H., Takahashi M
- Journal Title
  
  International Journal of Medical Sciences
  
  Volume: 7 Pages: 72-81
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow in tumor-bearing patients : an important role of bone marrow as a secondary lymhpoid organ2010
- Author(s)
  Murao A., Oka Y., Tsuboi A., Elisseeva O. A., Harada Y., Fujiki F., Nakajima H., Nishida S., Hosen N., Shirakata T., Hashimoto N., Myoui A., Ueda T., Takeda Y., Osaki T., Enomoto T., Yoshikawa H., Kimura T., Oji Y., Kawase I., Sugiyama H
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 848-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 peptide vaccine induces reduction in minimal residual disease in an imatinib-treated CML patient.2010
- Author(s)
  Oji Y., Oka Y., et al.
- Journal Title
  
  European Journal of Hematology
  
  Volume: 85 Pages: 358-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 peptide vaccine as a paradigm for" cancer antigen-derived peptide"-based immunotherapy for malignancies : Successful induction of ant-cancer effect by vaccination with a single kind of WT1 peptide2009
- Author(s)
  Oka Y., Tsuboi A., Fujiki F., Li Z., Nakajima H., Hosen N., Shirakata T., Nishida S., Oji Y., Kawase I., Sugiyama H
- Journal Title
  
  Anti-Cancer Agents in Medicinal Chemistry
  
  Volume: 9 Pages: 787-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 peptide immunotherapy for cancer in children and young adults.2009
- Author(s)
  Hashii Y, Sato E, Ohta H, Oka Y, Sugiyama H, Ozono K.
- Journal Title
  
  Pediat Blood Cancer 26
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] WT1 peptide vaccine as a paradigm for "cancer antigen-derived peptide" -based immunotherapy for malignancies : successful induction of anti-cancer effect by vaccination with a single kind of WT1 peptide2009
- Author(s)
  Oka Y., Tsuboi A., et al
- Journal Title
  
  Anticancer Agents in Medicinal Chemistry 9
  
  Pages: 787-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 (Wilms' tumor 1) peptide immunotherapy for childhood rhabdomyosarcoma : a case report2009
- Author(s)
  Ohta H., Hashii Y., Oka Y., Oji Y., Ozono K. et al (岡芳弘 : 15人中10番目、尾路祐介 : 15人中11番目)
- Journal Title
  
  Pediatric Hematology and Oncology 26
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] WT1 IgG antibody for early detection of non-small cell lung cancer and as its prognostic factor2009
- Author(s)
  Oji Y., Kitamura Y., Kamino E., Kitano A., Sawabata N., Inoue M., Mori M., Nakatsuka S-I., Sakaguchi N., Miyazaki K., Nakamura M., Fukuda I., Nakamura J., Tatsumi N., Takakuwa T., Nishida S., Shirakata T., Hosen N., Tsuboi A., Nezu R., Maeda H., Oka Y., Kawase I., Aozasa K., Okumura M., Miyoshi S., Sugiyama H
- Journal Title
  
  International Journal of Cancer
  
  Volume: 125 Pages: 381-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] WT1 peptide vaccine as a paradigm for “cancer antigen-derived peptide”-based immunotherapy for malignancies : successful induction of anti-cancer effect by vaccination with a single kind of WT1 peptide2009
- Author(s)
  Oka Y., Tsuboi A., et al
- Journal Title
  
  Anticancer Agents in Medicinal Chemistry
  
  Volume: 9 Pages: 787-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] 免疫療法の現況と今後の可能性(肺癌-基礎・臨床研究のアップデート-)2008
- Author(s)
  岡芳弘、川瀬一郎
- Journal Title
  
  日本臨床 66
  
  Pages: 658-665
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] Wilms' tumor gene WT1-shRNA as a potent apoptosis-inducing agent for solid tumors2008
- Author(s)
  Tatsumi N., Oji Y., Tsuji N., Oka Y., Sugiyama H. et al (岡芳弘 : 19人中18番目、尾路祐介 : 19人中2番目)
- Journal Title
  
  International Journal of oncology 32
  
  Pages: 707-711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] "Cancer antigen WT1 protein-derived peptide"-based treatment of cancer-Toward the further development-2008
- Author(s)
  Oka Y., Tsuboi A., Fujiki F., Shirakata T., Oji Y. et al (岡芳弘 : 11人中1番目、尾路祐介 : 11人中10番目)
- Journal Title
  
  Current Medicinal Chemistry 15
  
  Pages: 3052-3061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] 癌抗原WT1を標的とした免疫療法-WT1ペプチド癌ワクチン-2008
- Author(s)
  岡芳弘、川瀬一郎
- Journal Title
  
  日本臨床免疫学会会誌 31
  
  Pages: 375-382
- NAID
  10024961409
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] A WT1 protein-derived, naturally processed 16-mer peptide, WT1332, is a promiscuous helper peptide for induction of WT1-specific Th1-type CD4+ T cells.2008
- Author(s)
  Fujiki F, Oka Y, Kawakatsu M, Tsuboi A, Nakajima H, Elisseeva OA, Harada Y, Li Z, Tatsumi N, Kamino E, Shirakata T, Nishida S, Taniguchi Y, Kawase I, Oji Y, Sugiyama H.
- Journal Title
  
  Microbiol Immunol 52
  
  Pages: 591-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] “Cancer antigen WT1 protein-derived peptide"-based treatment of cancer-Toward the further development2008
- Author(s)
  Oka Y., et al
- Journal Title
  
  Current Medicinal Chemistry 15
  
  Pages: 3052-3061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] Phase II clinical trial of WT1(Wilms tumor gene) peptide vaccination for patients with recurrent glioblastoma2008
- Author(s)
  Izumoto S., Tsuboi A., Oka Y., Oji Y., et al (岡芳弘 : 22人中3番目、尾路祐介 : 22人中12番目)
- Journal Title
  
  Journal of Neurosurgery 108
  
  Pages: 963-971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] WT1 peptide vaccine for the treatment of cancer.2008
- Author(s)
  Oka Y., et al
- Journal Title
  
  Current Opinion in Immunology 20
  
  Pages: 211-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] WT1 peptide vaccine for the treatment of cancer2008
- Author(s)
  Oka Y., Tsuboi A., Oji Y., Kawase I., Sugiyama H.
- Journal Title
  
  Current Opinion in Immunology 20
  
  Pages: 211-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] Identification of a WT1 protein-derived peptide, WT1187 as an HLA-A*0206-restricted WT1-specific CTL epitope2008
- Author(s)
  Li Z., Oka Y., Tsuboi A., Oji Y. et al (岡芳弘 : 20人中2番目、尾路祐介 : 20人中19番目)
- Journal Title
  
  Microbiology and Immunology 52
  
  Pages: 551-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] A WT1 protein-derived, naturally processed 16-mer peptide, WT1332, is a promiscuous helper peptide for induction of WT1-specific Th1-type CD4+ T cells2008
- Author(s)
  Fujiki F., Oka Y., Kawakatsu M., Oji Y. et al(岡芳弘 : 16人中2番目、尾路祐介 : 16人中15番目)
- Journal Title
  
  Microbiology and Immunology 52
  
  Pages: 591-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] Identification of a WT1 protein-derived peptide, WT1187 as an HLA-A*0206-restricted, WT1-specific CTL epitope" is currently at the following stage of production.2008
- Author(s)
  Li Z, Oka Y, Tsuboi A, Fujiki F, Harada Y, Nakajima H, Masuda T, Fukuda Y, Kawakatsu M, Morimoto S, Katagiri T, Tatsumi N, Hosen N, Shirakata T, Nishida S, Kawakami Y, Udaka K, Kawase I, Oji Y, Sugiyama H.
- Journal Title
  
  Microbiol Immunol 52
  
  Pages: 551-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] WT1 peptide cancer vaccine for patients with hematopoietic malignancies and solid cancers2007
- Author(s)
  Oka Y., et. al.
- Journal Title
  
  The Scientific World JOURNAL 7
  
  Pages: 649-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] Clinical and immunologic responses to very low-dose vaccination with WT1 peptide (5 mug/body) in a patient with chronic myelomonocytic leukemia.2007
- Author(s)
  Kawakami M, Oka Y, Tsuboi A, Harada Y, Elisseeva OA, Furukawa Y, Tsukaguchi M, Shirakata T, Nishida S, Nakajima H, Morita S, Sakamoto J, Kawase I, Oji Y, Sugiyama H.
- Journal Title
  
  Int J Hematol 85
  
  Pages: 426-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Wilms' tumor geneWT1 peptide-based immunotherapy induced minimal response in a patient with advanced, therapy-resistant multiple myeloma2007
- Author(s)
  Tsuboi A., Oka Y., Nakajima H. Oji Y. et al (岡芳弘 : 21人中2番目、尾路祐介 : 21人中15番目)
- Journal Title
  
  International Journal of Hematology 86
  
  Pages: 414-417
- NAID
  10019533221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] Identification and characterization of a WT1 (Wilms' tumor gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes.2007
- Author(s)
  Fujiki F, Oka Y, Tsuboi A, Kawakami M, Nakajima H, Elisseeva OA, Harada Y, Ito K, Li Z, Tatsumi N, Sakaguchi N, Fujioka T, Masuda T, Yasukawa M, Udaka K, Oji Y, Sugiyama H.
- Journal Title
  
  J Immunother 30
  
  Pages: 282-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Development of WT1 peptide cancer vaccine against hematopoietic malignancies and solid cancers.2006
- Author(s)
  Oka, Y., et al.
- Journal Title
  
  Current Medicinal Chemistry 13
  
  Pages: 2345-2352
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201013
[Journal Article] A phase I/II trial of a WT1 (Wilms' Tumor Gene) peptide vaccine in patients with solid malignancy: Safety assessment based on the phase I data.2006
- Author(s)
  Morita S, Oka Y., Tsuboi A, Kawakami M, Maruno M, Izumoto S, Osaki T, Taguchi T, Ueda T, Myoui A, Nishida S, Shirakata T, Ohno S, Oji Y, Aozasa K, Hatazawa J, Udaka K, Yoshikawa H, Yoshimine T, Noguchi S, Kawase I, Nakatsuka S, Sugiyama H, Sakamoto J.
- Journal Title
  
  Japanese Journal of Clinical Oncology 36
  
  Pages: 231-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Generation of human tumor-specific, HLA class I-restricted Th1 and Tc1 cells by cell engineering with tumor peptide-specific T cell receptor genes.2005
- Author(s)
  Tsuji T, Yasukawa M, Matsuzaki J, Ohkuri T, Chamoto K, Wakita D, Azuma T, Niiya H, Miyoshi H, Kuzushima K, Oka Y, Sugiyama H, Ikeda H, Nishimura T.
- Journal Title
  
  Blood 106
  
  Pages: 470-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] WT1(235), a ninemer peptide derived from Wilms' tumor gene product, is a candidate peptide for the vaccination of HLA-A*0201-positive patients with hematopoietic malignancies.2005
- Author(s)
  Li Z, Oka Y, Tsuboi A, Masuda T, Tatsumi N, Kawakami M, Fujioka T, Sakaguchi N, Nakajima H, Fujiki F, Udaka K, Oji Y, Kawase I, Sugiyama H.
- Journal Title
  
  Int J Hematol 82
  
  Pages: 458-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies.2005
- Author(s)
  Wu F, Oka Y, Tsuboi A, Elisseeva O. A, Nakajima H, Fujiki F, Masuda T, Murakami M, Yoshihara S, Ikegame K, Hosen N, Kawakami M, Nakagawa M, Kubota T, Soma T, Yamagami T, Tsukaguchi M, Ogawa H, Oji Y, Hamaoka T, Kawase I, Sugiyama H.
- Journal Title
  
  Leukemia 19
  
  Pages: 268-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Induction of WT1(Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004
- Author(s)
  Oka Y., et. al.
- Journal Title
  
  Proc Natl Acad Sci USA 101
  
  Pages: 13885-13890
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15109007
[Journal Article] Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004
- Author(s)
  Oka, Y., et al.
- Journal Title
  
  Proceedings of National Academy of Science USA 101
  
  Pages: 13885-13890
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Induction of WT1 (Wilms' tumor gene)-specific cytotoxic Tlymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004
- Author(s)
  Oka, Y.et al.
- Journal Title
  
  Proceedings of National Academy of Science USA 101・38
  
  Pages: 13885-13890
- Data Source
  KAKENHI-PROJECT-15109007
[Journal Article] Induction of WT1(Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004
- Author(s)
  Oka, Y, et. al.
- Journal Title
  
  Proc Natl Acad. Sci USA 101
  
  Pages: 13885-13890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15109007
[Journal Article] Induction of WT1 (Wilms tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004
- Author(s)
  Oka, Y.et al.
- Journal Title
  
  Proceedings of National Academy of Science USA 101・38
  
  Pages: 13885-13890
- Data Source
  KAKENHI-PROJECT-14030044
[Journal Article] WT1 peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome(MDS) or MDS with myelofibrosis.2003
- Author(s)
  Oka, Y, et. al.
- Journal Title
  
  International Journal of Hematology 78
  
  Pages: 56-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15109007
[Journal Article] WT1 peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndome(MDS)or MDS with myelofibrosis.2003
- Author(s)
  Oka Y., et al.
- Journal Title
  
  International Journal of Hematology 78
  
  Pages: 56-61
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15109007
[Journal Article] HLA-DRB1*05:01-restricted WT1332-specific TCR-transduced CD4+ T lymphocytes display a helper activity for WT1-specific CTL induction and a cytotoxicity against leukemia cells.
- Author(s)
  Lin Y., Fujiki F., Katsuhara A., Oka Y., Tsuboi A., Aoyama N., Tanii S., Nakajima H., Tatsumi N., Morimoto S., Tamanaka T., Tachino S., Hosen N., Nishida S., Oji Y., Kumanogoh A., Sugiyama H.
- Journal Title
  
  Journal of Immunotherapy
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] WT1 IgG antibody for early detection of non-small cell lung cancer and as its prognostic factor
- Author(s)
  Oji Y., Kitamura Y., Kamino E., Kitano A., Oka Y., Kawase I., et.al. (岡芳弘 : 27人中22番目、尾路祐介 : 27人中1番目)
- Journal Title
  
  International Journal of Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590894
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8 T cells in bone marrow in tumor-bearing patients : Animportant role of bone marrow as a secondary lymphoid organ
- Author(s)
  Murao A., Oka Y., et al.
- Journal Title
  
  Cancer Science
- Description
  in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8 T cells in bone marrow in tumor-bearing patients : An important role of bone marrow as a secondary lymphoid organ
- Author(s)
  Murao A., Oka Y., et al.
- Journal Title
  
  Cancer Science (in press)
- NAID
  10026590478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 急性骨髄性白血病に対するWT1ワクチン療法の進捗2017
- Author(s)
  中田　潤、中江吉希、川上　学、岡　芳弘 et al
- Organizer
  第9回血液疾患免疫療法学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09173
[Presentation] 切除不能進行膵臓癌に対するゲムシタビン併用HLA拘束性WT1ペプチドワクチン療法で誘導されたWT1特異的CTLの免疫学的機能解析2017
- Author(s)
  森本創世子、西田純幸、岡　芳弘、杉山治夫ら
- Organizer
  第21回日本がん免疫学会学術総会
- Data Source
  KAKENHI-PROJECT-15K09173
[Presentation] Randamized phase II study of WT1 peptide vaccine plus gemcitabine for advanced pancreatic ductal adenocarcinoma (PDAC): Clinical efficacy and immune response.2016
- Author(s)
  Nishida S., Ishikawa T., Kokura S., Egawa S., Koido S., Yasuda H., Yanagimoto H., Ishii J., Kanno Y., Oba M.S., Sato M., Morimoto S., Eguchi H., Nagano H., Homma S., Oka Y., Morita S., Sugiyama H.
- Organizer
  2016 ASCO Annual Meeting
- Place of Presentation
  McCormick Place I、Chicago、Illiois、USA
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09173
[Presentation] An open-label phase II randomized trial of WI1 peptide vaccine plus gemcitabine for advanced pancreatic cancer.2016
- Author(s)
  Ishikawa T., Nishida S., Egawa S., Koido S., Ishii J., Kanno Y., Yanagimoto H., Kokura S., Morimoto S., Oba M.S., Oka Y., Sugiyama H.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K09173
[Presentation] 急性骨髄性白血病に対するWT1ワクチン療法2016
- Author(s)
  中田　潤、中江吉希、川上　学、森本創世子、藤木文博、中島博子、西田純幸、保仙直毅、坪井昭博、尾路祐介、岡　芳弘、杉山治夫
- Organizer
  第8回血液疾患免疫療法学会学術集会
- Place of Presentation
  北海道大学医学部学友会館「フラテ」、札幌市
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-15K09173
[Presentation] WT1ペプチドを用いたがんワクチン療法2015
- Author(s)
  岡　芳弘
- Organizer
  第13回日本組織適合性学会近畿地方会
- Place of Presentation
  大阪市
- Year and Date
  2015-02-07
- Invited
- Data Source
  KAKENHI-PROJECT-24591164
[Presentation] WT1 peptide IgG autoantibody: a predictive marker for WT1 peptide-based immunotherapy for glioblastoma.2015
- Author(s)
  岩井美樹、尾路祐介、村上由衣、橋本直哉、坪井昭博、保仙直樹、西田純幸、中田　潤、中島博子、岡　芳弘、吉峰俊樹、杉山治夫
- Organizer
  第7４回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K09173
[Presentation] 再発悪性神経膠芽腫を対象としたWT1キラーペプチドとWT1ヘルパーペプチドを用いた免疫療法　第１相試験2014
- Author(s)
  坪井昭博、橋本直哉、岡　芳弘、森本創世子、尾路祐介、保仙直毅、西田純幸、中田　潤、中江吉希、中島博子、吉峰俊樹、杉山治夫
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山市
- Year and Date
  2014-07-31
- Data Source
  KAKENHI-PROJECT-24591164
[Presentation] 悪性神経膠腫に対するWT1ペプチドワクチン療法の効果増強の試み2014
- Author(s)
  坪井昭博、橋本直哉、香川尚己、泉本修一、岡　芳弘、尾路祐介、森本創世子、保仙直毅、西田純幸、中田　潤、中江吉希、吉峰俊樹、杉山治夫
- Organizer
  第27回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  大阪市
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-24591164
[Presentation] WT1 peptide-based immunotherapy combined with Temozoromide for patients with newly diagnosed glioblastoma2014
- Author(s)
  Tsuboi A., Hashimoto N., Kagawa N., Izumoto S., Oka Y., Oji Y., Hosen N., Nishida S., Morimoto S., Yoshimine T., Sugiyama H.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24591164
[Presentation] がん抗原ペプチドを用いたワクチン治療の原理・現況・将来展望 -WT1ペプチドがんワクチンをそのモデルとして- シンポジウム(招待)2013
- Author(s)
  岡芳弘、杉山治夫
- Organizer
  第11回日本組織適合性学会近畿地方会
- Place of Presentation
  大阪.
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] Biased usage of T cell receptor β-chain variable region genes of cancer antigen WT1-specific CTLs in patients with solid tumors and healthy donors2012
- Author(s)
  Morimoto S., Oka Y., Tsuboi A., Fujiki F., Nakajima H., Hosen N., Oji Y., Kumanogoh A., Sugiyama H
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] Haruo Sugiyama, Keiichi Oaono2012
- Author(s)
  Yo shi ko Hshi i, Takako Miyamura, Risa Matsumura, Hisao Yoshida, Emiko Miyashita, Akihiro Tsuboi, Yusuke Oji, Naoki Hosen, Yoshihiro Oka
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 再発ハイリスク同種造血幹細胞移植後患者に対するWT1ペプチドワクチン第1相臨床試験.2012
- Author(s)
  保仙直毅、前田哲生、福島健太郎、森本創世子、中田潤、中江吉希、西田純幸、坪井昭博、近藤忠一、門脇則光、日野雅之、尾路祐介、岡芳弘、熊ノ郷淳、金倉譲、杉山治夫.
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] HLA class II-restricted WT1332-specific TCR-transduced CD4+ T lymphocytes display a helper activity for WT1-specific CTL induction and a cytotoxicity against leukemia cells2012
- Author(s)
  Lin Y., Fujiki F., Katsuhara A., Oka Y., Tsuboi A., Aoyama N., Tanii S., Nakajima H., Tatsumi N., Morimoto S., Tamanaka T., Tachino S., Hosen N., Nishida S., Oji Y., Kumanogoh A., Sugiyama H
- Organizer
  The 6th International Conference on WT1 in Human Neoplasia
- Place of Presentation
  京都
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1 peptide vaccination following allogeneic stem cell transplantation in pediatric patients2012
- Author(s)
  Yo shi ko Hshi i, Takako Miyamura, Risa Matsumura, Hisao Yoshida, Emiko Miyashita, Akihiro Tsuboi, Yusuke Oji, Naoki Hosen, Yoshihiro Oka, keiichi Ozono, Haruo Sugiyama
- Organizer
  The 6th International Conference on WT1 In Human Neoplasia
- Place of Presentation
  京都
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンを用いた小児血液腫瘍に対する同種造血幹細胞移植後免疫療法.2012
- Author(s)
  橋井佳子、宮村能子、松村梨紗、吉田寿雄、宮下恵実子、平松英文、谷澤昭彦、坪井昭博、尾路祐介、保仙直毅、岡芳弘、杉山治夫、.大薗恵一
- Organizer
  第4回造血器腫瘍免疫療法研究会学術総会
- Place of Presentation
  金沢
- Year and Date
  2012-08-18
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 慢性期CMLに対するイマチニブ併用WT1ペプチドワクチン免疫療法2012
- Author(s)
  尾路祐介、岡芳弘、坪井昭博、保仙直毅、西田純幸、中田潤、中江吉希、中島博子、藤木文博、辰巳直也、杉山治夫
- Organizer
  第4回造血器腫瘍免疫療法研究会学術総会
- Place of Presentation
  金沢
- Year and Date
  2012-08-18
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] International harmonization on immunohistochemical evaluation of WT1 positivity in solid cancers.2012
- Author(s)
  Oji Y., Berneman Z.N., Keilholz U., O'Reilly R., Saglio G., Wagner N., Heike Y., Lundin E., Morii E., Pauwells P., Pappotti M., Anguille S., Cilloni D., Letsch A., Ohashi H., Ohno Y., Waelput W., Duregon E., Hiraoka N., Udaka K., Izumoto S., Ohno S., Iwaf
- Organizer
  The 6th International Conference on WT1 in Human Neoplasia
- Place of Presentation
  京都
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ヘルパーペプチド投与による抗腫瘍免疫反応の増強マウスモデルを用いた検討2012
- Author(s)
  中島博子、岡芳弘、坪井昭博、藤木文博、辰巳直也、尾路祐介、杉山治夫
- Organizer
  第4回造血器腫瘍免疫療法研究会学術総会
- Place of Presentation
  金沢
- Year and Date
  2012-08-18
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] chair person with Z. N. Bernemann, Section VI: Immunotherapy II: Clinical trials in solid cancers2012
- Author(s)
  Yo shi hi ro Oka
- Organizer
  in The 6th International Conference on WT1 in Human Neoplasia
- Place of Presentation
  京都
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1 immunohistochemical staining and evaluation of WT1 positivity in solid cancers.2012
- Author(s)
  尾路祐介、福田菜莉、森井英一、辰己直也、北条望、村上由衣、斉藤千紗恵、鈴木望友、川田紗世、澄川美穂子、坪井昭博、岡芳弘、杉山治夫
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌.
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] Cancer vaccine therapy and patients' quality of life, cover-makeup for unsightly skin reaction.2012
- Author(s)
  分田貴子、西田純幸、坪井昭博、保仙直毅、尾路祐介、梅田智恵、種村篤、片山一郎、岡芳弘、杉山治夫、平家勇司
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] Phase II trial of WT1 peptide vaccine to gynecologic malignancies which are resistant to conventional chemotherapy.2012
- Author(s)
  森本晶子、上田豊、宮武崇、榎本隆之、岡芳弘、西田純幸、坪井昭博、白方俊章、尾路祐介、森田智視、坂本純一、杉山治夫、木村正
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌.
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] Wilms tumor 1 (WT1) peptide vaccine as an enhancer of graft versus leukemia effects.2012
- Author(s)
  Hosen N., Maeda T., Fukushima K., Morimoto S., Nakata J., Nakae Y., Takashima S., Nakajima H., Fujiki F., Tatsumi N., Nishida S., Tsuboi A., Kondo T., Hino M., Oji Y., Oka Y., Kumanogoh A., Sugiyama H
- Organizer
  The 6th International Conference on WT1 in Human Neoplasia
- Place of Presentation
  京都
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 再発ハイリスク同種造血幹細胞移植患者に対するWT1ペプチドワクチン第1相臨床試験2012
- Author(s)
  保仙直毅、前田哲生、福島健太郎、近藤忠一、日野雅之、岡芳弘、熊ノ郷淳、金倉譲、杉山治夫
- Organizer
  第4回造血器腫瘍免疫療法研究会学術総会
- Place of Presentation
  金沢
- Year and Date
  2012-08-18
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] Cancer antigen WT1-specific helper and suppressive Th17 derived from a single precursor cell2012
- Author(s)
  Tachino S, Oka Y, Fujiki F, Tsuboi A, Tamanaka T, Kondo K, Hosen N, Oji Y, Kumanogoh A, Sugiyama H
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 再発ハイリスク同種造血幹細胞移植後患者に対するWT1ペプチドワクチン第1相臨床試験2012
- Author(s)
  保仙直毅、前田哲夫、福島健太郎、近藤忠一、日野雅之、岡芳弘、熊ノ郷淳、金倉譲、杉山治夫.
- Organizer
  第16回日本がん免疫学会総会
- Place of Presentation
  札幌.
- Year and Date
  2012-07-28
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1 peptide vaccination combined with IFN-βenhances tumor rejection in a mice model2011
- Author(s)
  Nakajima H., Oka Y., Tsuboi A., Tatsumi N., Fujiki F., Morimoto S., Hosen N., Shirakata T., Nishida S., Oji Y., Sugiyama H
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 腫瘍抗原WT1特異的ヒトTh17細胞クローンの樹立と機能解析/ Establishment and characterization of tumor antigen WT1-specific human Th17 clone2011
- Author(s)
  Tachino S, Fujiki F., Oka Y., Tsuboi A., Nakajima H., Hosen N., Oji Y., Kumanogoh A., Sugiyama H
- Organizer
  第40回日本免疫学会学術総会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] A phase I study of WT1 peptide based cancer vaccine combined with gemcitabine for advanced pancreatic cancer2010
- Author(s)
  Nishida S., Oka Y., ら
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] WT1 peptide vaccine for the treatment of malignancies. Symposium 1(Cancer Immunotherapy : Current Status and Future Prospects)2010
- Author(s)
  Oka Y, Sugiyama H
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] WT1 peptide immunotherapy has achieved long-term complete remission for the patients with acute myeloid leukemia with minimal residual disease2010
- Author(s)
  Tsuboi A., Oka Y., ら
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] MDSに対するWT1ペプチドワクチン療法第I相r臨床試験2010
- Author(s)
  坪井昭博、岡芳弘, ら
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 担癌患者の骨髄中には末梢血に比較して癌抗原WT1特異的CD8+T細胞がより高頻度かつ未熟な状態で存在する2010
- Author(s)
  岡芳弘、村尾綾子, ら
- Organizer
  第14回日本がん免疫学会総会
- Place of Presentation
  熊本市
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] ペプチドワクチン-WT1ペプチド癌ワクチンをモデルとして-.シンポジウム(「臓器移植の将来の展望-HLAの医療への関与-」2010
- Author(s)
  岡芳弘
- Organizer
  第8回日本組織適合性学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] WT1 peptide vaccine for the treatment of malignancies2010
- Author(s)
  Oka Y, Sugiyama H.
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜市(招待講演)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] Induction of complete and molecular repmissions in acute myeloid leukemia by Wilms'tumor 1 antigen-targeted dendritic cell vaccination2010
- Author(s)
  Berneman Z.N., Oka Y., ら
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 同種造血幹細胞移植後の難治性小児血液腫瘍患者に対するWT1ペプチドワクチンを用いた免疫療法2010
- Author(s)
  橋井佳子、岡芳弘, ら
- Organizer
  第23回バイオセラピィ学会学術集会総会
- Place of Presentation
  大阪市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 同種造血幹細胞移植後の難治性小児血液腫瘍患者に対する WT1 ペプチドワクチンを用いた免疫療法2010
- Author(s)
  橋井佳子、太田秀明、松村梨沙、吉田寿雄、楠木重範、佐藤恵実子、坪井昭博、尾路祐介、岡芳弘、杉山治夫、大薗恵一
- Organizer
  第52回日本小児血液学会
- Place of Presentation
  大阪
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 膠芽腫に対するWT1ペプチドワクチン療法における長期生存例と予後予測因子2010
- Author(s)
  橋本直哉、岡芳弘, ら
- Organizer
  第23回バイオセラピィ学会学術集会総会
- Place of Presentation
  大阪市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] WT1 peptide vaccine for the treatment of solid and hematological malignancies. Symposium 10(Cancer and Immunity)2010
- Author(s)
  Oka Y, Sugiyama H
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 担癌患者の骨髄中には末梢血に比較して癌抗原WT1特異的CD8^+ T細胞がより高頻度かつ未熟な状態で存在する2010
- Author(s)
  岡芳弘、村尾綾子、坪井昭博、田中ゆきえ、藤木文博、中島博子、西田純幸、保仙直毅、尾路祐介、杉山治夫
- Organizer
  第14回日本がん免疫学会総会
- Place of Presentation
  熊本
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 悪性グリオーマに対するWT1ワクチン療法;治療反応性予測因子としてのDTHとmethionine PET2010
- Author(s)
  橋本直哉、岡芳弘, ら
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] WT1 peptide vaccine for the treatment of solid and hematological malignancies2010
- Author(s)
  Oka Y., Sugiyama H.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市(招待講演)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] グリベックとの併用によるCMLに対するWT1ペプチドワクチン免疫療法2009
- Author(s)
  尾路祐介、岡芳弘、西田純幸、白方俊章、保仙直毅、坪井昭博、中島博子、村尾綾子、杉山治夫
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1 IgG抗体は非小細胞肺癌の早期診断と予後診断に有用なマーカーである2009
- Author(s)
  北野愛子、尾路祐介、中村三千代、岡芳弘ら(岡芳弘 : 9人中2番目、尾路祐介 : 9人中7番目)
- Organizer
  第日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] WT-1 peptide vaccine2009
- Author(s)
  岡芳弘
- Organizer
  14^<th> congress of the European Hematology Association
- Place of Presentation
  ベルリン(ドイツ)
- Year and Date
  2009-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] MDSに対するWT1ワクチン療法2009
- Author(s)
  坪井昭博、岡芳弘、川上学、尾路祐介、保仙直毅、西田純幸、米谷昇、杉山治夫
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT-1 peptide vaccine2009
- Author(s)
  岡芳弘
- Organizer
  14^<th> congress of the European Hematology Association
- Place of Presentation
  ベルリン (ドイツ)
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-21590991
[Presentation] 大腸癌、膵癌に対するWT1ペプチドワクチン療法2008
- Author(s)
  岡芳弘、西田純幸、武田裕、尾路祐介ら(岡芳弘 : 10人中1番目、尾路祐介 : 10人中5番目)
- Organizer
  第21回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  東京
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] 進行大腸癌に対するHLA-A*2402拘束性WT1ワクチン療法第I/II相臨床試験2008
- Author(s)
  西田純幸、岡芳弘、坪井昭博、尾路祐介ら(岡芳弘 : 10人中2番目、尾路祐介 : 10人中5番目)
- Organizer
  第日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] グリベックとの併用によるCMLに対するWT1ペプチドワクチン免疫療法2008
- Author(s)
  尾路祐介、岡芳弘、西田純幸、白方俊章ら(岡芳弘 : 10人中2番目、尾路祐介 : 10人中1番目)
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] MDS-AMLに対しHLA-A*2402拘束性改変型WT1ペプチドワクチン療法を行い、長期間AMLの再発なく経過している1例2008
- Author(s)
  西田純幸、川上学、坪井昭博、村尾綾子、宮井沙緒里、白方俊章、保仙直毅、尾路祐介、塚口真知子、岡芳弘、杉山治夫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] グリベックとの併用によるCMLに対するWT1ペプチドワクチン免疫療法2008
- Author(s)
  尾路祐介、白方俊章、岡芳弘、西田純幸、坪井昭博、保仙直毅、杉山治夫
- Organizer
  第89回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] MDS-AMLに対しHLA-A*2402拘束性改変型WT1ペプチドワクチン療法を行い、長期間AMLの再発なく経過している1例2008
- Author(s)
  西田純幸、川上学、坪井昭博、村尾綾子、尾路祐介、岡芳弘ら(岡芳弘 : 11人中10番目、尾路祐介 : 11人中8番目)
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] グリベックとの併用によるCMLに対するWT1ペプチドワクチン免疫療法2008
- Author(s)
  尾路祐介、岡芳弘、西田純幸、白方俊章、保仙直毅、高橋和子、村尾綾子、中島博子、坪井昭博、杉山治夫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 再発神経膠腫に対するWT1ペプチドワクチン療法-臨床第2相試験-2008
- Author(s)
  橋本直哉、坪井昭博、泉本修一、岡芳弘ら(6人中4番目)
- Organizer
  第日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] MRDを有する再発高リスク急性骨髄性白血病患者にWT1ワクチン療法行い5年以上の寛解を維持している3症例2008
- Author(s)
  坪井昭博、岡芳弘、西田純幸、尾路祐介ら(岡芳弘 : 9人中2番目、尾路祐介 : 9人中6番目)
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] WT1ペプチドワクチン療法を行い2008
- Author(s)
  西田純幸、岡芳弘、坪井昭博、杉山治夫、川上学、塚口真知子
- Organizer
  長期間AMLの再発なく経過しているMDS-AMLの1例、第89回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] shRNA targeting WT1 17AA(+) isoforms is a potent apotosis-inducing agent for solid tumors2007
- Author(s)
  辰巳直也、尾路祐介、東尾麻里、岡芳弘ら(尾路祐介 : 9人中2番目、岡芳弘 : 9人中8番目)
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] Co-administration of WT1 peptide vaccine and IFN-・enhances tumor rejection compared to the injection of WT1 peptide vaccine alone in a mouse model.2007
- Author(s)
  Nakajima H, Oka Y, Tsuboi A, Oji Y, Sugiyama H.
- Organizer
  3rd International Conference on WT1 in Human Malignancies
- Place of Presentation
  Berlin
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ペプチドワクチン療法により長期に血液学的寛解を維持しているAML3症例2007
- Author(s)
  岡芳弘、坪井昭博、尾路祐介、川瀬一郎ら(岡芳弘 : 15人中1番目、尾路祐介 : 15人中13番目)
- Organizer
  第69回日本血液学会/第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] 癌抗原WT1を標的とした癌ワクチン療法2007
- Author(s)
  岡芳弘, ら
- Organizer
  日本臨床免疫学会
- Place of Presentation
  ホテル阪急エクスポパーク(吹田市)
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] リアルタイムPCRを用いた担癌患者末梢血中のWT1特異的CD4陽性T細胞の定量的解析2007
- Author(s)
  藤木文博、岡芳弘、川勝真衣、尾路祐介ら(岡芳弘 : 12人中2番目、尾路祐介 : 12人中11番目)
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] Single cell RT-PCR法を用いた、WT1ワクチン投与患者体内でのWT1特異的CTLクローンの動態解析2007
- Author(s)
  原田ゆきえ、岡芳弘、川上学ら(16人中2番目)
- Organizer
  第69回日本血液学会/第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] WT1 peptide vaccination at very low-dose for myelodysplastic syndrome.2007
- Author(s)
  Kawakami M, Oka Y, Tsuboi A, Harada Y, Elisseeva OA, Furukawa Y, Hayashi T, Nishida S, Shirakata T; Hosen N, Nakajima H, Yamagami T, Soma T, Oji Y, Sugiyama H.
- Organizer
  3rd International Conference on WT1 in Human Malignancies
- Place of Presentation
  Berlin
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] Production of anti-Wilms tumor gene WT1 IgG antibody in patients with non small lung cancer (NSCLC)2007
- Author(s)
  尾路祐介、北村弥生、上農枝里子、北野愛子、岡芳弘、三好新一郎、杉山治夫
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] 顎下腺患者に対するWT1ペプチド癌ワクチン療法2007
- Author(s)
  白方俊章、猪原秀典、岡芳弘、尾路祐介、久保武ら(岡芳弘 : 11人中3番目、尾路祐介 : 11人中7番目)
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] 多発性骨髄腫に対してWT1ペプチドワクチンを行って有効であった一例2007
- Author(s)
  坪井昭博、岡芳弘、西田純幸、白方俊章、尾路祐介、杉山治夫
- Organizer
  第69回日本血液学会/第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] Single cell RT-PCR法を用いた、WT1ワクチン投与患者体内でのWT1特異的CTLクローンの動態解析2007
- Author(s)
  原田ゆきえ、岡芳弘、川上学、尾路祐介ら(岡芳弘 : 13人中2番目、尾路祐介 : 13人中11番目)
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] 改良型WT1ペプチドワクチン投与後に誘導されるWT1-CTLの頻度とペプチドの応答性について2007
- Author(s)
  鈴木進、渡辺正人、岡芳弘、恵美宣彦ら(7人中4番目)
- Organizer
  第69回日本血液学会/第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19590894
[Presentation] 分子再発後にWT1ワクチンを投与し長期寛解を維持している急性骨髄性白血病の3例2006
- Author(s)
  尾路祐介, 坪井昭博, 西田純幸, 白方俊章, 杉山治夫, 岡芳弘, 川上学
- Organizer
  第86回近畿血液学地方会
- Place of Presentation
  和歌山
- Year and Date
  2006-11-18
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 骨髄異形成症候群(MDS)に対する少量WT1ペプチド療法2006
- Author(s)
  川上学、坪井昭博、西田純幸、白方俊章、原田ゆきえ、中島博子、藤木文博、李哲雨、OLGA ELISSEEVA、尾路祐介、古川佳央、林孝昌、岡芳弘、杉山治夫
- Organizer
  第68回日本血液学会総会・第48回日本臨床血液学会総会合同総会
- Place of Presentation
  福岡
- Year and Date
  2006-10-07
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 分子再発急性骨髄性白血病に対してWT1ペプチドワクチン療法施行し長期血液学的寛解を維持している3症例2006
- Author(s)
  西田純幸、坪井昭博、岡芳弘、川上学、中島博子、OLGA ELISSEEVA、許泰一、杉山治夫
- Organizer
  第68回日本血液学会総会・第48回日本臨床血液学会総会合同総会
- Place of Presentation
  福岡
- Year and Date
  2006-10-09
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ペプチド癌ワクチン投与患者末梢血中のWT1特異的CTLの解析2006
- Author(s)
  岡芳弘、OLGA ELISSEEBA、長谷浩志、川上学、西田純幸、白方俊章、原田ゆきえ、中島博子、李哲雨、藤木文博、尾路祐介、川瀬一郎、坪井昭博、杉山治夫
- Organizer
  第68回日本血液学会総会・第48回日本臨床血液学会総会合同総会
- Place of Presentation
  福岡
- Year and Date
  2006-10-07
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1(Wilms' tumor gene) peptide-based immunotherapy for myelodysplastic syndrome2005
- Author(s)
  Haruo Sugiyama, Akihiro Tsuboi, Manabu Kawakami Yusuke Oji, Yoshihiro Oka
- Organizer
  8th International Symposium on Myelodysplastic Syndromes MDS 2005
- Place of Presentation
  長崎
- Year and Date
  2005-05-14
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1 specific CTLs in WT1 peptide vaccine-treated patients2005
- Author(s)
  Olga Elisseeva, Yoshihiro Oka, Akihiro Tsuboi, Hiroshi Hase, Hiroko Nakajima, Yukie Harada, Manabu Kawakami, Fumihiro Fujiki, Sumiyuki Nishida, Toshiaki Shirakata, Satoshi Oono, Ichirou Kawase, Yusuke Oji, Haruo Sugiyama
- Organizer
  The Second International Conference on WT1 in Human Neoplasia
- Place of Presentation
  Kyoto
- Year and Date
  2005-10-22
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] Identification and characterization of a WT1 (Wilms' tumor gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes2005
- Author(s)
  Fumihiro Fujiki, Yoshihiro Oka, Akihiro Tsuboi, Manabu Kawakami, Mai Kawakatsu, Hiroko Nakajima, Olga A. Elisseeva, Yukie Harada, Ken Ito, Zheyu Li, Naoya Tatsumi, Nao Sakaguchi, Tatsuya Fujioka, Tomoki Masuda, Masaki Yasukawa, Keiko Udaka, Yusuke Oji, Haruo Sugiyama
- Organizer
  The Second International Conference on WT1 in Human Neoplasia
- Place of Presentation
  Kyoto
- Year and Date
  2005-10-21
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 少量WT1ペプチド療法により慢性骨髄単球性白血病(CMML)の進行が抑制された1例2005
- Author(s)
  川上学, 坪井昭博, 西田純幸, 白方俊章, 岡芳弘, 尾路祐介, 杉山治夫, 古川佳央
- Organizer
  第83回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2005-06-11
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 骨髄異形成症候群(MDS)に対する少量WT1ペプチド療法2005
- Author(s)
  川上学, 坪井昭博、原田ゆきえ, 中島博子, 白方俊章, 大野智, 藤木文博, 李哲雨, エリセーバ・オリガ, 尾路祐介, 古川佳央, 岡芳弘, 杉山治夫
- Organizer
  第9回基盤的癌免疫研究会総会
- Place of Presentation
  東京
- Year and Date
  2005-07-15
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] Increase in numbers of antigen-experienced CD45RA+CD-CCR7+WT1-specific CTLs correlate with clinical response to WT1 vaccine2005
- Author(s)
  エリセーバ・オリガ, 長谷浩志, 坪井昭博, 岡芳弘, 杉山治夫
- Organizer
  第9回基盤的癌免疫研究会総会
- Place of Presentation
  東京
- Year and Date
  2005-07-15
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ペプチドワクチン療法が奏効した多発性骨髄腫の1例2005
- Author(s)
  坪井昭博, 川上学, 西田純幸, 中島博子, 岡芳弘, 白方俊章, 大野智, 尾路祐介, 杉山治夫
- Organizer
  第83回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2005-06-11
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1特異的CD4*ヘルパーT細胞を誘導できるHLA-classII拘束性ペプチドの同定2005
- Author(s)
  藤木文博, 岡芳弘, 坪井昭博, 川上学, 川勝真衣, 中島博子, オリガ・エリセーバ, 原田ゆきえ, 李哲雨, 伊藤憲, 宇高恵子, 尾路祐介, 杉山治夫
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-16
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ワクチンによる特異的細胞傷害性T細胞の解析2005
- Author(s)
  エリセーバ・オリガ, 長谷浩志, 坪井昭博, 岡芳弘, 杉山治夫
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-16
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1-peptide vaccination for acute myeloid leukemia2005
- Author(s)
  Manabu Kawakami, Yoshihiro Oka, Akihiro Tsuboi, Hiroko Nakajima, Olga A. Elisseeva, Hiroshi Hase, Yukie Harada, Fumihiro Fujiki, Zheyu LI, Tatsumi, Sumiyuki Nishida, Satoshi Ohno, Toshiaki Shirakata, Ichiro Kawase, Yusuke Oji, Haruo Sugiyama
- Organizer
  The Second International Conference on WT1 in Human Neoplasia
- Place of Presentation
  Kyoto
- Year and Date
  2005-10-22
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] がん抗原ペプチドを用いたワクチン治療の原理・現況・将来展望　－WT1ペプチドがんワクチンをそのモデルとして－
- Author(s)
  岡　芳弘ら
- Organizer
  第11回日本組織適合性学会近畿地方会
- Place of Presentation
  参天製薬株式会社（大阪）
- Invited
- Data Source
  KAKENHI-PROJECT-24591164

1. OJI Yusuke (20294100)

# of Collaborated Projects: 17 results

# of Collaborated Products: 50 results
2. OGAWA Hiroyasu (80194447)

# of Collaborated Projects: 17 results

# of Collaborated Products: 0 results
3. SOMA Toshihiro (40273619)

# of Collaborated Projects: 16 results

# of Collaborated Products: 0 results
4. SUGIYAMA Haruo (70162906)

# of Collaborated Projects: 15 results

# of Collaborated Products: 34 results
5. TATEKAWA Toyoshi

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
6. MIYAKE Seigo (60294097)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. TAKEDA YOSHITO (40452388)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
8. HASHII Yoshiko (60343258)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. OTSUKA Tomoyuki (20730576)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TSUBOI Akihiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. HOSEN Naoki (10456923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
12. FUJIKI Fumihiro (40456926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
13. OSAKI TADASHI (50324778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHTA Hideaki (60322187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. MIYASHITA Emiko (40528395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. TAKAHASHI Ryo (10546865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAGATOMO Izumi (10570583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NOMURA Taisei (90089871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HONGYO Tadashi (90271569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAJIMA Hiroo (20237275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. FUJIKAWA Kazuo (90247958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ADACHI Shigeki (60379261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KOMORI Toshihisa (00252677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 宮村能子 (20379796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 梁治子 (90301267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 谷慶彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MENSSEN H.D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MARGOLIS Dav

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 川上学

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. AKIHIRO Tsuboi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 小守寿文

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. NISHIDA Sumiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
33. Morimoto Soyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
34. KIDA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. CHIBA Yasuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 井上義一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 橋本直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKA Yoshihiro 岡 芳弘

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Analysis of immune response against cancer, which may lead to establishment of WT1 peptide-based immunotherapy for the conventional treatment-resistant malignancies in the respiratory medicine fieldPrincipal Investigator

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Development of WT1 peptide-based immunotherapy for inoperable thoracic malignant tumors, and analysis of immunodynamics of the novel therapyPrincipal Investigator

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Cancer antigen WT1-targeting peptide vaccine therapy for lung cancerPrincipal Investigator

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Development of WT1 peptide cancer vaccine targeting lung cancerPrincipal Investigator

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Development of cancer immunotherapy targeting WT1 which highly expresses in patients with hematopoictic maliganacies including leukemia.Principal Investigator

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肺癌に対する、WT1を標的とした癌ワクチンの開発Principal Investigator

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OKA Yoshihiro 岡芳弘