Sugiyama Haruo 杉山治夫

… Alternative Names

SUGIYAMA Haruo 杉山治夫

杉山.治夫ハルオスギヤマハルオ

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Researcher Number	70162906
Other IDs
Affiliation (Current)	2023: 大阪大学, 大学院医学系研究科, 寄附講座教授
Affiliation (based on the past Project Information) *help	2009: Osaka University, 大学院・医学系研究科, 教授 2003 – 2009: OSAKA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE, PROFESSOR, 医学系研究科, 教授 2007: Osaka University, 医学研究科, 教授 2007: Osaka University, 医学糸研究科, 教授 1995 – 2002: 大阪大学, 医学部, 教授 … More 2000: 大阪大学, 医学系研究科, 教授 1994: 大阪大学, 医学部, 講師 1986 – 1993: 大阪大学, 医学部, 助手 1992: 大阪大学, 医学部第三内科, 助手 1991: 大阪大学, 医学部・第3内科, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Biological Sciences / Immunology / Hematology Except Principal Investigator 環境影響評価(含放射線生物学) / Pathological medical chemistry / Biological Sciences
Keywords	Principal Investigator WT1 / 白血病 / leukemia / oncogene / WT1遺伝子 / leukemogenesis / tumor suppressor gene / WT1アッセイ / Abelsonマウス白血病ウイルス / 造血幹細胞 … More / 免疫療法 / Wilms' tumor gene / 骨髄異形成症候群 / ウイルムス腫瘍遺伝子 / Stat3 / 32D細胞 / 微小残存病変 / MRD / 微少残存病変 / 造血幹細胞株 / 温度感受性変異株 / 免疫グロブリン遺伝子の再構成 / Abelsonウイルス / immunoglobulin heavy chain variable region genes / V_Hgene family / 免疫グロブリンH鎖 / 免疫グロブリン可変部領域遺伝子 / immunotherany / myelochisplastic syndrome / Wilm's tumor gene / single-cell RT-PCR / 32D / tumor marker / cell cycle / M / G2 / CD34 / ウィルムス腫瘍遺伝子 / oncogenic / 白血病腫瘍マーカー / apoptosis / The WT1 gene / WWドメイン / アポトーシス / hematopoietic progenitor cells / 32D cells / M期 / G_2 / がん遺伝子 / がん抑制遺伝子 / Wilms tumor gene / Abelson ウイルス / 免疫学 / 癌 / 遺伝子 / 免役療法 / 分子標的治療法 / 分子標的治療 / 分子標的療法 / 分子診断 / 遺伝子診断 / WT1結合タンパク / 顆粒球系コロニー / G-CSF / MDS / AML / real time PCR / WT1 assay / ドナーリンパ球輸注 / 骨髄移植 / 化学療法 / subtraction hybridization / ヒト造血幹細胞 / SCIDマウス / bcr-abl / リボザイム / 遺伝子治療 / 慢性骨髄性白血病 / RT-PCR / go130 / IL-6レセプター / IL-6 / non-Hodgkin's lymphoma / cDNAサブトラクション / 幼若B細胞 / サブトラクション / DNA結合タンパク / 遺伝子再構成 / Ig遺伝子 / Dexture culture / Stem cell line / T細胞抗原レセプタ-遺伝子 / 免疫グロブリンH鎖遺伝子 / B細胞の分化 / 温度感受性Abelsonウイルス / recombinase / ts mutant … More Except Principal Investigator 白血病 / WT1遺伝子 / Leukemia / パラクライン / サイトカイン / ヒト癌細胞 / GeneChip / human thyroid hormone / mutation in human thyroid tissue / radio-iodine / ^<137>Cs γ-rays / mouse with human tissues / improved SDID mice / radiation damage in human tissue / 超臨界事故 / 放射線ヨード / ヒト甲状腺障害 / 137Csガンマ線 / ジーンチップ / ヒト甲状腺ホルモン分泌能 / ヒト甲状腺遺伝子変異 / 放射性ヨード / ^<137>Csガンマ線 / ヒト臓器・組織置換マウス / 重度複合免疫不全マウス / 放射線ヒト臓器・組織障害 / Lung cancer / WT1 gene / WT1 / ウイルムス腫瘍遺伝子 / 肺癌 / WTl gene / Biological concentration / Wild animals and plants / Ecological effects / Genetic effects / Chernobyl catastrophe / Low dose radiations / 野生動植物 / 遺伝的影響 / 白血球 / 生物学的濃縮 / 野性動植物 / 生態系への影響 / 遺伝子影響 / チェルノブイリ核施設崩壊 / 微量放射線 / Mutation / Mortality and malformation / Solid tumor / Genetic risk / Physical risk / Dose rate effectiveness factor / Low dose and low dose rate radiation / 突然変異 / 致死と奇形 / 固型腫瘍 / 遺伝的リスク / 身体的リスク / 線量率効果係数 / 低線量・低線量率放射線 / キメラ / クリスタリン遺伝子 / 形質転換 / 奇形がん腫細胞 / 細胞分化 / B系幹細胞株 / yes関連遺伝子 / SV40 / transformation / Mo-MSV / 癌抑制遺伝子 / 細胞変異株 / 細胞因子 / WT1 mRNA / 遺伝性乳癌 / 微小転移 / 易罹患性 / 遺伝子診断 / 乳癌 / 化学療法感受性 / 予後 / ATAC-PCR / 遺伝子発現プロファイル / 乳がん / β-FGF / TNF-α / TGF-β / IL-6 / IL-1 / 癌増殖 / オートクライン Less

Development of molecular diagnosis and molecule-targeted therapy for leukemiaPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
WT1 protein-targeted immunotherapy for leulemiaPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
WT1アッセイを用いた、白血病及び類縁疾患の遺伝子診断Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Role of the Wilms' tumor gene WT1 in human leukemogenesisPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
乳がんの遺伝子診断とその臨床応用
- Principal Investigator
  
  野口眞三郎
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
EFFECT OF RADIATION EXPOSURE ON HUMAN ORGAN/TISSUE AND I'TS EXPERIMENTAL PROTECTION AND THERAPY
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  OSAKA UNIVERSITY
WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
転写因子WT1の造血幹細胞の増殖,分化の制御に果たす役割の解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
The role of the tumor suppressor gene WT1 in human leukemogenesis.Principal Investigator
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Oncogenic role of the Wilms' tumor gene in tumorigenesis of lung cancer
- Principal Investigator
  
  OJI Yusuke
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
白血病の遺伝子診断と白血病治療の個別化Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
転写因子WT1の造血幹細胞の増殖、分化の制御に果たす役割の解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
微小残存白血病細胞の新しい検出法の確立による白血病の個性化した治療法の開発Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Analysis of roles of tumor suppressor gene WT1 in human leukemogenesis.Principal Investigator
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
微少残存白血病細胞の新しい検出法の確立による白血病の新しい治療法の開発Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Genetic Effects of Low Dose Radiations in Man and Animals
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Osaka University
Role of the tumor suppressor gene WT1 in human leukemogenesis.Principal Investigator
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
微少残存白血病細胞の新しい検出法の確立による白血病の新しい治療法の開発Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Dose and dose rate effectiveness to determine the risk of low dose radiation to human
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Osaka University
多能性造血幹細胞に特異的に発現する新しい分子の単離Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
ヒトがん細胞のパラクライン因子とがん増殖の免疫生物学的研究
- Principal Investigator
  
  小倉剛
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokushima
慢性骨髄性白血病に対する遺伝子治療に向けのての基礎研究Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
hIL-6/SCIDマウスを用いた、ヒト造血幹細胞の定量とヒト造血系の再構築Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
ヒトがん細胞のパラクライン因子とがん増殖の免疫生物学的研究
- Principal Investigator
  
  小倉剛
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokushima
造血幹細胞株の樹立とその分化の分子生物的解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
悪性リンパ腫でのIL-6とその関連遺伝子発現の解析と新しい治療法の確立Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
温度感受性変異株を用いたAbelsonマウス白血病ウイルスの発がん機構の解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
温度感受性変異レトロウイルスを用いた造血幹細胞株の樹立と分子生物学解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
免疫グロブリン遺伝子の再構成に関与するrecombinaseの単離Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
幼弱B細胞の分化を駆動させるcDNAクロ-ンの単離Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
温度感受性レトロウイルスを用いた造血幹細胞株の樹立と分子生物学的解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
温度感受性変異株を用いたAbelsonウイルスの発ガン機構の解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
免疫グロブリンH鎖遺伝子の再構成に関与する核内因子のcDNAクロ-ニングPrincipal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
温度感受性変異株を用いたAbelsonウイルスの発ガン機構の解析Principal Investigator
- Principal Investigator
  
  杉山治夫
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Analysis of the mechanisms of V_H gene selection in theformation of immunoglovulin heavy chain variable region genes.Principal Investigator
- Principal Investigator
  
  SUGIYAMA Haruo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University Medical School
癌遺伝子産物の発現に関与する細胞因子
- Principal Investigator
  
  羽倉明
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
組織特異的に発現する遺伝子を用いた腫瘍細胞における遺伝子発現機構の発生工学的研究
- Principal Investigator
  
  岡田節人
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Okazaki National Research Institutes

All 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Biased usage of BV gene families of T cell receptors of WT1 (Wilms' tumor gene)-specific CD8+ T cells in patients with myeloid malignancies2010
- Author(s)
  Tanaka-Harada Y, Kawakami M, Oka Y, Tsuboi A, Katagiri T, Elisseeva O, Nishida S, Shirakata T, Hosen N, Fujiki F, Murao A, Nakajima H, Oji Y, Kanda Y, Kawase I, Sugiyama H.
- Journal Title
  
  Cancer Science 101
  
  Pages: 594-600
- NAID
  10026589035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow (BM) in tumor-bearing patients: an important role of BM as a secondary lymphoid organ.2010
- Author(s)
  Murao A, Oka Y, Tsuboi A, Elisseeva OA, Harada Y, Fujiki F, Nakajima H, Nishida S, Hosen N, Shirakata T, Hashimoto N, Myoui A, Ueda T, Takeda Y, Osaki T, Enomoto T, Yoshikawa H, Kimura T, Oji Y, Kawase I, Sugiyama H.
- Journal Title
  
  Cancer Science (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Prognostic Significance of WT1 mRNA and anti-WT1 Antibody Levels in Peripheral Blood in Patients with Myelodysplastic Syndromes.2010
- Author(s)
  Tamura H, Dan K, Yokose N, Iwakiri R, Ohta M, Sakamaki H, Tohyama K, Kondo A, Hyodo H, Nakamura K, Yamashita T, Elisseeva O. A, Oka Y, Oji Y, Sugiyama H, Ogata K.
- Journal Title
  
  Leukemia Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] WT1 peptide immunotherapy for cancer in children and young adults.2009
- Author(s)
  Hashii Y, Sato E, Ohta H, Oka Y, Sugiyama H, Ozono K.
- Journal Title
  
  Pediat Blood Cancer 26
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] A WT1 protein-derived, naturally processed 16-mer peptide, WT1332, is a promiscuous helper peptide for induction of WT1-specific Th1-type CD4+ T cells.2008
- Author(s)
  Fujiki F, Oka Y, Kawakatsu M, Tsuboi A, Nakajima H, Elisseeva OA, Harada Y, Li Z, Tatsumi N, Kamino E, Shirakata T, Nishida S, Taniguchi Y, Kawase I, Oji Y, Sugiyama H.
- Journal Title
  
  Microbiol Immunol 52
  
  Pages: 591-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Identification of a WT1 protein-derived peptide, WT1187 as an HLA-A*0206-restricted, WT1-specific CTL epitope" is currently at the following stage of production.2008
- Author(s)
  Li Z, Oka Y, Tsuboi A, Fujiki F, Harada Y, Nakajima H, Masuda T, Fukuda Y, Kawakatsu M, Morimoto S, Katagiri T, Tatsumi N, Hosen N, Shirakata T, Nishida S, Kawakami Y, Udaka K, Kawase I, Oji Y, Sugiyama H.
- Journal Title
  
  Microbiol Immunol 52
  
  Pages: 551-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Identification and characterization of a WT1 (Wilms' tumor gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes.2007
- Author(s)
  Fujiki F, Oka Y, Tsuboi A, Kawakami M, Nakajima H, Elisseeva OA, Harada Y, Ito K, Li Z, Tatsumi N, Sakaguchi N, Fujioka T, Masuda T, Yasukawa M, Udaka K, Oji Y, Sugiyama H.
- Journal Title
  
  J Immunother 30
  
  Pages: 282-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Clinical and immunologic responses to very low-dose vaccination with WT1 peptide (5 mug/body) in a patient with chronic myelomonocytic leukemia.2007
- Author(s)
  Kawakami M, Oka Y, Tsuboi A, Harada Y, Elisseeva OA, Furukawa Y, Tsukaguchi M, Shirakata T, Nishida S, Nakajima H, Morita S, Sakamoto J, Kawase I, Oji Y, Sugiyama H.
- Journal Title
  
  Int J Hematol 85
  
  Pages: 426-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] A phase I/II trial of a WT1 (Wilms' Tumor Gene) peptide vaccine in patients with solid malignancy: Safety assessment based on the phase I data.2006
- Author(s)
  Morita S, Oka Y., Tsuboi A, Kawakami M, Maruno M, Izumoto S, Osaki T, Taguchi T, Ueda T, Myoui A, Nishida S, Shirakata T, Ohno S, Oji Y, Aozasa K, Hatazawa J, Udaka K, Yoshikawa H, Yoshimine T, Noguchi S, Kawase I, Nakatsuka S, Sugiyama H, Sakamoto J.
- Journal Title
  
  Japanese Journal of Clinical Oncology 36
  
  Pages: 231-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies.2005
- Author(s)
  Wu F, Oka Y, Tsuboi A, Elisseeva O. A, Nakajima H, Fujiki F, Masuda T, Murakami M, Yoshihara S, Ikegame K, Hosen N, Kawakami M, Nakagawa M, Kubota T, Soma T, Yamagami T, Tsukaguchi M, Ogawa H, Oji Y, Hamaoka T, Kawase I, Sugiyama H.
- Journal Title
  
  Leukemia 19
  
  Pages: 268-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] Generation of human tumor-specific, HLA class I-restricted Th1 and Tc1 cells by cell engineering with tumor peptide-specific T cell receptor genes.2005
- Author(s)
  Tsuji T, Yasukawa M, Matsuzaki J, Ohkuri T, Chamoto K, Wakita D, Azuma T, Niiya H, Miyoshi H, Kuzushima K, Oka Y, Sugiyama H, Ikeda H, Nishimura T.
- Journal Title
  
  Blood 106
  
  Pages: 470-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Journal Article] WT1(235), a ninemer peptide derived from Wilms' tumor gene product, is a candidate peptide for the vaccination of HLA-A*0201-positive patients with hematopoietic malignancies.2005
- Author(s)
  Li Z, Oka Y, Tsuboi A, Masuda T, Tatsumi N, Kawakami M, Fujioka T, Sakaguchi N, Nakajima H, Fujiki F, Udaka K, Oji Y, Kawase I, Sugiyama H.
- Journal Title
  
  Int J Hematol 82
  
  Pages: 458-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] MDSに対するWT1ワクチン療法2009
- Author(s)
  坪井昭博、岡芳弘、川上学、尾路祐介、保仙直毅、西田純幸、米谷昇、杉山治夫
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] グリベックとの併用によるCMLに対するWT1ペプチドワクチン免疫療法2009
- Author(s)
  尾路祐介、岡芳弘、西田純幸、白方俊章、保仙直毅、坪井昭博、中島博子、村尾綾子、杉山治夫
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 骨髄異形成症候群における末梢血WT1mRNA発現と抗WT1抗体産生の臨床的意義2009
- Author(s)
  田村秀人、緒方清行、横瀬紀夫、岩切理歌、大田雅嗣、坂巻壽、遠山薫、山下泰史、近藤麻加、兵働英也、中村恭子、尾路祐介、杉山治夫、壇和夫
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] グリベックとの併用によるCMLに対するWT1ペプチドワクチン免疫療法2008
- Author(s)
  尾路祐介、岡芳弘、西田純幸、白方俊章、保仙直毅、高橋和子、村尾綾子、中島博子、坪井昭博、杉山治夫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] グリベックとの併用によるCMLに対するWT1ペプチドワクチン免疫療法2008
- Author(s)
  尾路祐介、白方俊章、岡芳弘、西田純幸、坪井昭博、保仙直毅、杉山治夫
- Organizer
  第89回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ペプチドワクチン療法を行い2008
- Author(s)
  西田純幸、岡芳弘、坪井昭博、杉山治夫、川上学、塚口真知子
- Organizer
  長期間AMLの再発なく経過しているMDS-AMLの1例、第89回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] MDS-AMLに対しHLA-A*2402拘束性改変型WT1ペプチドワクチン療法を行い、長期間AMLの再発なく経過している1例2008
- Author(s)
  西田純幸、川上学、坪井昭博、村尾綾子、宮井沙緒里、白方俊章、保仙直毅、尾路祐介、塚口真知子、岡芳弘、杉山治夫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1 peptide vaccination at very low-dose for myelodysplastic syndrome.2007
- Author(s)
  Kawakami M, Oka Y, Tsuboi A, Harada Y, Elisseeva OA, Furukawa Y, Hayashi T, Nishida S, Shirakata T; Hosen N, Nakajima H, Yamagami T, Soma T, Oji Y, Sugiyama H.
- Organizer
  3rd International Conference on WT1 in Human Malignancies
- Place of Presentation
  Berlin
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] Co-administration of WT1 peptide vaccine and IFN-・enhances tumor rejection compared to the injection of WT1 peptide vaccine alone in a mouse model.2007
- Author(s)
  Nakajima H, Oka Y, Tsuboi A, Oji Y, Sugiyama H.
- Organizer
  3rd International Conference on WT1 in Human Malignancies
- Place of Presentation
  Berlin
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ペプチド癌ワクチン投与患者末梢血中のWT1特異的CTLの解析2006
- Author(s)
  岡芳弘、OLGA ELISSEEBA、長谷浩志、川上学、西田純幸、白方俊章、原田ゆきえ、中島博子、李哲雨、藤木文博、尾路祐介、川瀬一郎、坪井昭博、杉山治夫
- Organizer
  第68回日本血液学会総会・第48回日本臨床血液学会総会合同総会
- Place of Presentation
  福岡
- Year and Date
  2006-10-07
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 分子再発後にWT1ワクチンを投与し長期寛解を維持している急性骨髄性白血病の3例2006
- Author(s)
  尾路祐介, 坪井昭博, 西田純幸, 白方俊章, 杉山治夫, 岡芳弘, 川上学
- Organizer
  第86回近畿血液学地方会
- Place of Presentation
  和歌山
- Year and Date
  2006-11-18
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 骨髄異形成症候群(MDS)に対する少量WT1ペプチド療法2006
- Author(s)
  川上学、坪井昭博、西田純幸、白方俊章、原田ゆきえ、中島博子、藤木文博、李哲雨、OLGA ELISSEEVA、尾路祐介、古川佳央、林孝昌、岡芳弘、杉山治夫
- Organizer
  第68回日本血液学会総会・第48回日本臨床血液学会総会合同総会
- Place of Presentation
  福岡
- Year and Date
  2006-10-07
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 分子再発急性骨髄性白血病に対してWT1ペプチドワクチン療法施行し長期血液学的寛解を維持している3症例2006
- Author(s)
  西田純幸、坪井昭博、岡芳弘、川上学、中島博子、OLGA ELISSEEVA、許泰一、杉山治夫
- Organizer
  第68回日本血液学会総会・第48回日本臨床血液学会総会合同総会
- Place of Presentation
  福岡
- Year and Date
  2006-10-09
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1(Wilms' tumor gene) peptide-based immunotherapy for myelodysplastic syndrome2005
- Author(s)
  Haruo Sugiyama, Akihiro Tsuboi, Manabu Kawakami Yusuke Oji, Yoshihiro Oka
- Organizer
  8th International Symposium on Myelodysplastic Syndromes MDS 2005
- Place of Presentation
  長崎
- Year and Date
  2005-05-14
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1 (Wilms'tumor Gene) Peptide-Based Cancer Immunotherapy2005
- Author(s)
  Sugiyama H
- Organizer
  10th JAPANESE-GERMAN WORKSHOP
- Place of Presentation
  Essen
- Year and Date
  2005-10-01
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] Increase in numbers of antigen-experienced CD45RA+CD-CCR7+WT1-specific CTLs correlate with clinical response to WT1 vaccine2005
- Author(s)
  エリセーバ・オリガ, 長谷浩志, 坪井昭博, 岡芳弘, 杉山治夫
- Organizer
  第9回基盤的癌免疫研究会総会
- Place of Presentation
  東京
- Year and Date
  2005-07-15
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ワクチンによる特異的細胞傷害性T細胞の解析2005
- Author(s)
  エリセーバ・オリガ, 長谷浩志, 坪井昭博, 岡芳弘, 杉山治夫
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-16
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ペプチドワクチン療法が奏効した多発性骨髄腫の1例2005
- Author(s)
  坪井昭博, 川上学, 西田純幸, 中島博子, 岡芳弘, 白方俊章, 大野智, 尾路祐介, 杉山治夫
- Organizer
  第83回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2005-06-11
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1-peptide vaccination for acute myeloid leukemia2005
- Author(s)
  Manabu Kawakami, Yoshihiro Oka, Akihiro Tsuboi, Hiroko Nakajima, Olga A. Elisseeva, Hiroshi Hase, Yukie Harada, Fumihiro Fujiki, Zheyu LI, Tatsumi, Sumiyuki Nishida, Satoshi Ohno, Toshiaki Shirakata, Ichiro Kawase, Yusuke Oji, Haruo Sugiyama
- Organizer
  The Second International Conference on WT1 in Human Neoplasia
- Place of Presentation
  Kyoto
- Year and Date
  2005-10-22
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1 specific CTLs in WT1 peptide vaccine-treated patients2005
- Author(s)
  Olga Elisseeva, Yoshihiro Oka, Akihiro Tsuboi, Hiroshi Hase, Hiroko Nakajima, Yukie Harada, Manabu Kawakami, Fumihiro Fujiki, Sumiyuki Nishida, Toshiaki Shirakata, Satoshi Oono, Ichirou Kawase, Yusuke Oji, Haruo Sugiyama
- Organizer
  The Second International Conference on WT1 in Human Neoplasia
- Place of Presentation
  Kyoto
- Year and Date
  2005-10-22
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1ペプチドを用いた免疫療法2005
- Author(s)
  杉山治夫
- Organizer
  第9回基盤的癌免疫研究会総会
- Place of Presentation
  東京
- Year and Date
  2005-07-15
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] Identification and characterization of a WT1 (Wilms' tumor gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes2005
- Author(s)
  Fumihiro Fujiki, Yoshihiro Oka, Akihiro Tsuboi, Manabu Kawakami, Mai Kawakatsu, Hiroko Nakajima, Olga A. Elisseeva, Yukie Harada, Ken Ito, Zheyu Li, Naoya Tatsumi, Nao Sakaguchi, Tatsuya Fujioka, Tomoki Masuda, Masaki Yasukawa, Keiko Udaka, Yusuke Oji, Haruo Sugiyama
- Organizer
  The Second International Conference on WT1 in Human Neoplasia
- Place of Presentation
  Kyoto
- Year and Date
  2005-10-21
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 少量WT1ペプチド療法により慢性骨髄単球性白血病(CMML)の進行が抑制された1例2005
- Author(s)
  川上学, 坪井昭博, 西田純幸, 白方俊章, 岡芳弘, 尾路祐介, 杉山治夫, 古川佳央
- Organizer
  第83回近畿血液学地方会
- Place of Presentation
  大阪
- Year and Date
  2005-06-11
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] 骨髄異形成症候群(MDS)に対する少量WT1ペプチド療法2005
- Author(s)
  川上学, 坪井昭博、原田ゆきえ, 中島博子, 白方俊章, 大野智, 藤木文博, 李哲雨, エリセーバ・オリガ, 尾路祐介, 古川佳央, 岡芳弘, 杉山治夫
- Organizer
  第9回基盤的癌免疫研究会総会
- Place of Presentation
  東京
- Year and Date
  2005-07-15
- Data Source
  KAKENHI-PROJECT-17015028
[Presentation] WT1特異的CD4*ヘルパーT細胞を誘導できるHLA-classII拘束性ペプチドの同定2005
- Author(s)
  藤木文博, 岡芳弘, 坪井昭博, 川上学, 川勝真衣, 中島博子, オリガ・エリセーバ, 原田ゆきえ, 李哲雨, 伊藤憲, 宇高恵子, 尾路祐介, 杉山治夫
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-16
- Data Source
  KAKENHI-PROJECT-17015028

1. OKA Yoshihiro (20273691)

# of Collaborated Projects: 21 results

# of Collaborated Products: 34 results
2. OGAWA Hiroyasu (80194447)

# of Collaborated Projects: 15 results

# of Collaborated Products: 0 results
3. SOMA Toshihiro (40273619)

# of Collaborated Projects: 15 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 11 results

# of Collaborated Products: 29 results
6. 中川雅史

# of Collaborated Projects: 7 results

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8. NOMURA Taisei (90089871)

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10. 小守寿文

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11. 山上保

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# of Collaborated Products: 10 results
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Sugiyama Haruo 杉山 治夫

SUGIYAMA Haruo 杉山 治夫

杉山.治夫 ハルオ スギヤマ ハルオ

Research Projects

Research Products

Co-Researchers

Development of molecular diagnosis and molecule-targeted therapy for leukemiaPrincipal Investigator

Principal Investigator

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Research Institution

WT1 protein-targeted immunotherapy for leulemiaPrincipal Investigator

Principal Investigator

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WT1アッセイを用いた、白血病及び類縁疾患の遺伝子診断Principal Investigator

Principal Investigator

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Research Institution

Role of the Wilms' tumor gene WT1 in human leukemogenesisPrincipal Investigator

Principal Investigator

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乳がんの遺伝子診断とその臨床応用

Principal Investigator

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Research Institution

EFFECT OF RADIATION EXPOSURE ON HUMAN ORGAN/TISSUE AND I'TS EXPERIMENTAL PROTECTION AND THERAPY

Principal Investigator

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Research Institution

WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

転写因子WT1の造血幹細胞の増殖,分化の制御に果たす役割の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of the tumor suppressor gene WT1 in human leukemogenesis.Principal Investigator

Principal Investigator

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Research Institution

Oncogenic role of the Wilms' tumor gene in tumorigenesis of lung cancer

Principal Investigator

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白血病の遺伝子診断と白血病治療の個別化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

転写因子WT1の造血幹細胞の増殖、分化の制御に果たす役割の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Sugiyama Haruo 杉山治夫

SUGIYAMA Haruo 杉山治夫

杉山.治夫ハルオスギヤマハルオ