Ryo Haruko 梁治子

… Alternative Names

Researcher Number	90301267
Other IDs
Affiliation (Current)	2019: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所難治性疾患研究開発・支援センター, 研究サブリーダー
Affiliation (based on the past Project Information) *help	2017 – 2019: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所難治性疾患研究開発・支援センター, 研究サブリーダー 2016: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所疾患モデル小動物研究室, 研究サブリーダー 2011 – 2014: 独立行政法人医薬基盤研究所, 難病・疾患資源研究部, サブプロジェクトリーダー 2010: 独立行政法人医薬基盤研究所, プロジェクトサブリーダー 2010: 独立行政法人医薬基盤研究所, 難病・疾患資源研究部, プロジェクトサブリーダー … More
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) / Risk sciences of radiation and chemicals Except Principal Investigator Risk sciences of radiation/Chemicals / Hygiene / Basic Section 52040:Radiological sciences-related / 環境影響評価(含放射線生物学) / Risk sciences of radiation and chemicals / Experimental pathology
Keywords	Principal Investigator マイクロサテライト / マイクロサテライト変異 / 核実験周辺住民 / 性細胞の変異 / 放射能被ばくの遺伝的リスク / 放射能被ばくのリスク / 次世代影響 / human mutation / 生殖細胞突然変異 / 紫外線 … More Except Principal Investigator ヒト臓器・組織置換マウス / マウス / 放射性ヨード / 継世代的影響 / Super-SCIDマウス / ヒト甲状腺ホルモン分泌能 / 放射線ヨード / 重度複合免疫不全マウス / 放射線ヒト臓器・組織障害 / mouse with human tissues / 遺伝子変異と発現 / Food chain / 粒子線治療 / 低線量率放射線被 / ヒト臓器・組織 / 遺伝子発現 / K-ras遺伝子 / Low dose radiation / change in gene expression / 化学物質 / 低線量放射線測定 / p53がん抑制遺伝子 / ヒト前立腺肥大症 / ダイオキシン / 生物濃縮 / GeneChip / 遺伝的不安定性 / ヒト甲状腺障害 / 生物線量計 / 低線量率放射線被曝 / ヒト前立腺肥大症PDX / Environmental Contamination / ^<137>Csガンマ線 / 感受性 / Mouse / 疾病 / 低線量率放射線被爆 / 疾病との相関 / 中性子線 / 環境 / Transgenerational effects / Biodosimeter / 改良SCIDマウス / 人体影響 / 炭素線 / N5マウス / 肺がん / マイクロサテライト / 放射線、粒子線、X線 / 長期維持 / Low dose rate radiation / ヒト正常皮膚 / 核分裂放射能 / ヒト甲状腺遺伝子変異 / 137Csガンマ線 / 放射線、X線、粒子線 / PSA / 環境有害物質 / 食物連鎖 / 遺伝子損傷 / Teratogenicity / ヒト疾患移植モデル / 環境汚染 / 内部被曝 / 放射能汚染地域 / 住民と子孫の健康調査 / radioactive iodine / 病態解析 / ^<137>Cs γ-rays / 疾患 / radio-iodine / 突然変異 / Gene damages / 抑制効果 / ヒト臓器・組織障害 / severe combined immuno-deficiency / Radioactive contamination / human thyroid hormone / PDXモデル / Super-SCID / Genetic Effects / チェルノブイリ原発事故 / improved SDID mice / mutation in human tissues / 生殖毒性 / 放射能汚染 / ヒト組織遺伝子変異 / 皮膚癌 / 日光ケラトーシス / radiation damage in human tissue / 機能異常 / 遺伝子発現異常(ジーンチップ) / mutation in human thyroid tissue / Chernobyl catastrophe / 放射線、粒子線、Ｘ線 / c-kit遺伝子 / 催奇形性 / Reproductive toxicity / 放射線・化学物質 / Dioxins / functional damage / 継世代影響 / 超臨界事故 / ジーンチップ / 遺伝的影響 / 内部被爆 / fission radionuclides / 白血病 / 放射線の継世代影響 / メカニズム / Biological concentration / organ and tissue damage / 機能測定 Less

臨床肺がんおよび正常肺移植マウスモデルを用いた粒子線治療効果と副作用評価Ongoing
- Principal Investigator
  
  足立成基
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Japan-Russia Study on the Health Concern in Future Generation of Residents Exposed to Radionuclides in Radiation-contaminated AreaOngoing
- Principal Investigator
  
  野村大成
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
核物質汚染地域住民（カザフスタン）の子孫におけるマイクロサテライト変異の調査研究Principal InvestigatorOngoing
- Principal Investigator
  
  梁治子
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Establishment of human benign prostatic hyperplasia model in super-SCID mice and its pathological analysis
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  独立行政法人医薬基盤研究所
Direct effect of radiation and chemicals on human tissues and its mechanism
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  独立行政法人医薬基盤研究所
放射線、化学物質の継世代的(遺伝的)影響-マイクロサテライト突然変異誘発と疾病
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Biomedical Innovation
Development and analysis of human organ/tissue damage by fission radionuclides
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Osaka University
Genetic effects and biological concentration of radionuclides in plants and animals after Chernobyl catastrophe.
- Principal Investigator
  
  NAKAJIMA Hiroo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Osaka University
Transgenermonal mutations in the children of the liquidators who worked for the Chernobyl nuclear power plant accidentPrincipal Investigator
- Principal Investigator
  
  RYO Haruko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Osaka University
EFFECT OF RADIATION EXPOSURE ON HUMAN ORGAN/TISSUE AND I'TS EXPERIMENTAL PROTECTION AND THERAPY
- Principal Investigator
  
  NOMURA Taisei
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  OSAKA UNIVERSITY
Spermatotoxicity and Transgenerational Effects of Dioxin
- Principal Investigator
  
  NAKAJIMA Hiroo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Osaka University
A,B領域紫外線によるヒト皮膚がんと日光角化症の誘発と特異的遺伝子変異の関与
- Principal Investigator
  
  HONGYO Tadashi
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Tergite anormality induced by ultraviolet light in Drodophila melanogasterPrincipal Investigator
- Principal Investigator
  
  RYO Haruko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Osaka University

All 2017 2015 2014 2010 2008 2006 Other

All Journal Article Presentation

[Journal Article] Transgenerational effects of radiation on cancer and other disorders in mice and humans2017
- Author(s)
  Nomura Taisei、Baleva Larisa S、Ryo Haruko、Adachi Shigeki、Sipyagina Alla E、Karakhan Natalya M
- Journal Title
  
  Journal of Radiation and Cancer Research
  
  Volume: 8 Pages: 123-123
- DOI
  10.4103/jrcr.jrcr_30_17
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00555, KAKENHI-PROJECT-17H01623
[Journal Article] ヒトがん組織等移植SCIDマウスを用いた重粒子線治療の有効性・安全性の研究2015
- Author(s)
  野村大成、足立成基、梁　治子、坂巻　靖、鳥　正幸、吉留克英、野々村祝夫、古澤佳也、鵜澤玲子
- Journal Title
  
  平成26年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書
  
  Volume: 26 Pages: 56-58
- Data Source
  KAKENHI-PROJECT-23241023
[Journal Article] ヒトがん組織等移植SCIDマウスを用いた重粒子線治療の有効性・安全性の研究2015
- Author(s)
  野村大成、足立成基、梁　治子、坂巻　靖、鳥　正幸、吉留克英、野々村祝夫、古澤佳也、鵜澤玲子
- Journal Title
  
  平成26年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書
  
  Volume: 26 Pages: 56-58
- Data Source
  KAKENHI-PROJECT-26670196
[Journal Article] p53-Dependent Suppression of Genome Instability in Germ Cells2014
- Author(s)
  Otozai S, Ishikawa-Fujiwara T, Oda S, Kamei Y, Ryo H, Sato A, Nomura T, Mitani H, Tsujimura T, Inohara H, Todo T.
- Journal Title
  
  Mutation Research
  
  Volume: 760 Pages: 24-32
- DOI
  10.1016/j.mrfmmm.2013.12.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-21221003, KAKENHI-PROJECT-23241023, KAKENHI-PROJECT-24241018, KAKENHI-PROJECT-24310039, KAKENHI-PROJECT-24651048, KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-25281019, KAKENHI-PROJECT-25550029, KAKENHI-PROJECT-26670196
[Journal Article] Altered actions of memantine and NMDA-induced currents in new Grid2-deleted mouse line2014
- Author(s)
  Ayako Kumagai, Akira Fujita, Tomoki Yokoyama, Yuki Nonobe, Yasuhiro Hasaba, Tsutomu Sasaki, Yumi Itoh, Minako Koura, Osamu Suzuki, Shigeki Adachi, Haruko Ryo, Arihiro Kohara, Lokesh P. Tripathi, Masato Sanosaka, Toshiki Fukushima, Taisei Nomura, Hiroshi Takemori, et al.
- Journal Title
  
  Genes (Basel).
  
  Volume: 5 Pages: 1095-1114
- DOI
  10.3390/genes5041095
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241023, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-25670155, KAKENHI-PROJECT-25740023, KAKENHI-PROJECT-26430012, KAKENHI-PROJECT-26670196, KAKENHI-PROJECT-24390222
[Journal Article] Effects of Fission Neutrons on Human Thyroid Tissues Maintained in SCID Mice.2010
- Author(s)
  S.Adachi, H.Ryo, T.Hongyo, H.Nakajima, R.Tsuboi-Kikuya, Y.Tokita, F.Matsuzuka, K.Hiramatsu, K.Fujikawa, T.Itoh, T.Nomura
- Journal Title
  
  Mutat Res. 696
  
  Pages: 107-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241014
[Journal Article] No evidence of increased mutation rates at microsatellite loci in offspring of A-bomb survivors.2010
- Author(s)
  M.Kodaira, H.Ryo, N.Kamada, K.Furukawa, N.Takahashi, H.Nakajima, T.Nomura, N.Nakamura
- Journal Title
  
  Radiat.Res. 173
  
  Pages: 205-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241014
[Journal Article] Differential radiation sensitivity to morphological, functional and molecular changes of human thyroid tissues and bone marrow cells maintained in SCID mice.2008
- Author(s)
  T.Nomura, T.Hongyo, H.Nakajima, L.Y.Li, M.Syaifudin, S.Adachi, H.Ryo, R.Baskar, K.Fukuda, Y.Oka, H.Sugiyama, F.Matsuzuka.
- Journal Title
  
  Mutat Res. 657(1)
  
  Pages: 68-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241014
[Journal Article] Germ-line Mutations at a Mouse ESTR (Pc-3) Locus and Human Microsatellite Loci.2006
- Author(s)
  Ryo, H., et al.
- Journal Title
  
  J. Radiation Research 47: Suppl. B
  
  Pages: 31-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201013
[Journal Article] Germ-line Mutations at a Mouse ESTR (Pc-3) Locus and Human Microsatellite Loci.2006
- Author(s)
  Ryo, H., et al.
- Journal Title
  
  J.Radiation Research 47: Suppl.B
  
  Pages: 31-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201013
[Journal Article] Germ-Line Mutations at a Mouse ESTR (Pc-3) Locus and Human Microsatellite Loci.2006
- Author(s)
  Haruko Ryo
- Journal Title
  
  J.Radiat.Res. 47(in press)
- Data Source
  KAKENHI-PROJECT-16201013
[Journal Article] Germ-line Mutations at a Mouse ESTR (Pc-3) Locus and Human Microsatellite Loci.2006
- Author(s)
  Haruko Ryo, Hiroo Nakajima, Taisei Nomura
- Journal Title
  
  J. Radiation Research 47号
  
  Pages: 31-37
- Data Source
  KAKENHI-PROJECT-16201013
[Journal Article] Germ-Line Mutations at a Mouse ESTR (Pc-3) Locus and Human Microsatellite Loci.2006
- Author(s)
  Ryo, H.
- Journal Title
  
  J.Radiat.Res. 47(in press)
- Data Source
  KAKENHI-PROJECT-16406019
[Presentation] Transgenerational Effects of Radiation on Cancer and Other Disorders in Mice and Humans.2017
- Author(s)
  Nomura Т., Ryo H., Adachi S.
- Organizer
  XVI RUSSIAN CONGRESS
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-16K00555
[Presentation] Transgenerational Effects of Radiation on Cancer and Other Disorders in Mice and Humans.2017
- Author(s)
  Nomura Т., Ryo H., Adachi S.
- Organizer
  XVI RUSSIAN CONGRESS
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-17H01623
[Presentation] Suppressive Effects of AHCC on Human Renal Carcinoma Growth in Super-SCID Mice.2017
- Author(s)
  Nomura T., Adachi S., Ryo H., Hatanaka E., Kaji M., Yasuda K., Yoshii R.,Takada S., Yoshidome K., Nishioka H.
- Organizer
  ＩＣＮＩM 2017
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-17H01623
[Presentation] Suppression of Mouse and Human Cancer by AHCC.
- Author(s)
  Taisei Nomura, Shigeki Adachi, Haruko Ryo, Eiko Hatanaka, Momoyo Kaji, Koujun Yasuda.
- Organizer
  22nd ICNIM 2014
- Place of Presentation
  Hotel Royton Sapporo, Sapporo
- Year and Date
  2014-07-27 – 2014-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-23241023
[Presentation] Suppression of Mouse and Human Cancer by AHCC.
- Author(s)
  Taisei Nomura, Shigeki Adachi, Haruko Ryo, Eiko Hatanaka, Momoyo Kaji, Koujun Yasuda
- Organizer
  22nd ICNIM 2014
- Place of Presentation
  Hotel Royton Sapporo, Sapporo
- Year and Date
  2014-07-27 – 2014-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-26670196

1. NOMURA Taisei (90089871)

# of Collaborated Projects: 11 results

# of Collaborated Products: 15 results
2. NAKAJIMA Hiroo (20237275)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
3. ADACHI Shigeki (60379261)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
4. HONGYO Tadashi (90271569)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
5. FUJIKAWA Kazuo (90247958)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. YOSHIDOME Katsuhide (80598813)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. OKUMURA Meinosin (40252647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TODO Takeshi (90163948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MURAKAMI Masao (50210018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AKAGI Takashi (50500005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SUGIYAMA Haruo (70162906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OKA Yoshihiro (20273691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SAITO Tadashi (50153812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 笠井文生 (60393055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 振津かつみ (10418965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 坂巻靖 (70623693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NONOMURA Norio

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 中村敏明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 千森弘子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ODA Shoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. YOKOYAMA Tomoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. FUKUSHIMA Toshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 三谷啓志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 藤原智子(石川智子)

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 水口賢司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 竹森洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 田端俊英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 佐々木勉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 北川一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 長岡康夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ryo Haruko 梁 治子

梁 治子 リヨウ ハルコ

RYO Haruko 梁 治子

Research Projects

Research Products

Co-Researchers

臨床肺がんおよび正常肺移植マウスモデルを用いた粒子線治療効果と副作用評価Ongoing

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Review Section

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Japan-Russia Study on the Health Concern in Future Generation of Residents Exposed to Radionuclides in Radiation-contaminated AreaOngoing

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Research Institution

核物質汚染地域住民（カザフスタン）の子孫におけるマイクロサテライト変異の調査研究Principal InvestigatorOngoing

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Principal Investigator

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Transgenermonal mutations in the children of the liquidators who worked for the Chernobyl nuclear power plant accidentPrincipal Investigator

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Tergite anormality induced by ultraviolet light in Drodophila melanogasterPrincipal Investigator

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[Journal Article] Transgenerational effects of radiation on cancer and other disorders in mice and humans2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ヒトがん組織等移植SCIDマウスを用いた重粒子線治療の有効性・安全性の研究2015

Ryo Haruko 梁治子

梁治子リヨウハルコ

RYO Haruko 梁治子