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FUNAKOSHI Shinsuke  船越 信介

ORCIDConnect your ORCID iD *help
… Alternative Names

船越 信介  フナコシ シンスケ

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Researcher Number 20297352
Affiliation (based on the past Project Information) *help 2016: 慶應義塾大学, 医学部(信濃町), 講師(非常勤)
2014 – 2015: 慶應義塾大学, 医学部, 講師
2013 – 2014: 慶應義塾大学, 医学部, 講師(非常勤)
2010 – 2012: 慶應義塾大学, 医学部, 助教
2000 – 2001: 慶應義塾大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology
Except Principal Investigator
Gastroenterology / Gastroenterology
Keywords
Principal Investigator
細胞接着 / IGF / ShRNA / 胃癌 / 第1番染色体 / 癌抑制遺伝子 / RFLP marker / microsatellite marker / LOH / CDX2強制発現大腸癌細胞株 … More / Rac1 / c-MET / sp細胞 / CDX2強制発現大腸癌株 / ShRNA,siRNA / 免疫染色 / ShRNA, SiRNA / caveolin1 / 上皮間葉転換 / EGF / CDX2 / SP細胞 / 細胞接着関連タンパクの破綻 / 化学療法抵抗性大腸癌 / 大腸癌 / Cdx2 / C-MET / columnar morphogenesis / c-Met / SiRNA … More
Except Principal Investigator
胃癌 / バイオマーカー / sulfasaradine / HER2 / 胃がん / 抗がん剤 / 化学療法 / CD44 / 胃癌バイオマーカー / IL-7 / IL-7レセプター / 腸管免疫 / ジフテリア毒素 / トランスジェニックマウス / 炎症性腸疾患 / ノックアウトマウス / interleukin-7 / interleukin-7 receptor / mucosal immunology / knock-out mice / T lymphocytes / inflammatory bowel disease / diphteria toxin Less
  • Research Projects

    (5 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (8 People)
  •  Biomarker research for gastric cancer with proteomics and pathway analysis

    • Principal Investigator
      TAKAISHI HIROMASA
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  The Mechanism of disintegration and redifferentiation of cell adhesion proteins through CDX2 in chemotherapy refractory colorectal cancer.Principal Investigator

    • Principal Investigator
      FUNAKOSHI SHINSUKE
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  The Association between CDX2 and tyrosine kinases in chemotherapy refractory colorectal cancer and its mechanism.Principal Investigator

    • Principal Investigator
      FUNAKOSHI Shinsuke
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  ヒト胃癌における第1番染色体欠失地図の作成と癌抑制遺伝子の単離Principal Investigator

    • Principal Investigator
      船越 信介
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  New therapy targeting IL-7 receptor positive lymphocytes for chronic intestinal inflammation

    • Principal Investigator
      NAGANUMA Makoto
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University

All 2014 2013 2012 2011 Other

All Presentation

  • [Presentation] Rac1 accumulates in the nucleus at the invasive front of colorectal cancer through promoting cell motility2014

    • Author(s)
      Shinsuke Funakoshi
    • Organizer
      AACR(american association cancer research)
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-25460962
  • [Presentation] Rac1 Activation Promotes Invasive Phenotype of Side Population in Colon Cancer Cells by Destabilizing the E-cadherin-βcatenin Ligation2013

    • Author(s)
      Shinsuke Funakoshi
    • Organizer
      AACR meeting 2013
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] Rac1 Activation Promotes Invasive Phenotype of Side Population in Colon Cancer Cells by Destabilizing the E-cadherin-β-catenin Ligation2013

    • Author(s)
      Shinsuke Funakoshi et al
    • Organizer
      The AACR Annual Meeting 2013
    • Place of Presentation
      Washington DC
    • Year and Date
      2013-04-09
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] Inhibition of activated Rac1 signaling induces recovery of E-cadherin function and abrogation of invasive phenotype of side population in colon cancer cells.2013

    • Author(s)
      Shinsuke Funakoshi et al
    • Organizer
      The 6th International Gastrointestinal Consensus Symposium (IGICS)
    • Place of Presentation
      Tokyo
    • Year and Date
      2013-01-26
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] Rac1 Activation Promotes Invasive Phenotype of Side Population in Colon Cancer Cells by Destabilizing the E-cadherin-βcatenin Ligation.2012

    • Author(s)
      Shinsuke Funakoshi et al
    • Organizer
      The 8th International Symposium on cancer research and therapy
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] 大腸癌細胞株におけるside population cell の分離と活性型Rac1 の発現および運動能の解析2012

    • Author(s)
      船越信介 他
    • Organizer
      第21回日本癌病態治療研究会ワークショップ2「癌診療:基礎医学からの提言」
    • Place of Presentation
      前橋
    • Year and Date
      2012-07-06
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] Rac1 Activation Promotes Invasive Phenotype of Side Population in Colon Cancer Cells by Destabilizing the E-cadherin-βcatenin Ligation2012

    • Author(s)
      Shinsuke Funakoshi
    • Organizer
      The 8th International symposium on cancer research and therapy
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] Intestine-specific transcription factor Cdx2 enhances E-cadherin function in colon cancer cells through caveolin-1 mediated suppression of the c-Abl/CrkL/Rac1 signaling pathway2011

    • Author(s)
      船越信介
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] Intestine-specific transcription factor Cdx2 enhances E-cadherin functionin colon cancer cells through caveolin-1 mediated suppression of the c-Abl/CrkL/Rac1 signaling pathway2011

    • Author(s)
      Shinsuke Funakoshi et al
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22790670
  • [Presentation] Inhibition of activated Rac1 signaling induces recovery of E-cadherin function and abrogation of invasive phenotype of side population in colon cancer cells

    • Author(s)
      Shinsuke Funakoshi
    • Organizer
      The 6th international gastrointestinal consensus symposium
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22790670
  • 1.  AZUMA Toshifumi (00222612)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  LYNCH John P
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  TAKAISHI HIROMASA (80286468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  NAGANUMA Makoto (00265810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Mamoru (10175127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  HIBI Toshifumi (50129623)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  足立 雅之 (70338028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  須河 恭敬 (80772566)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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