KITAGAWA Kyoko 北川恭子

… Alternative Names

Kitagawa Kyoko 北川恭子

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Researcher Number	20299605
Other IDs
Affiliation (Current)	2025: 宮崎大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023: 宮崎大学, 医学部, 助教 2022: 金沢大学, がん進展制御研究所, 研究協力員 2020 – 2021: 産業医科大学, 医学部, 講師 2006 – 2018: Hamamatsu University School of Medicine, Medical, Research Associate, 医学部, 助教 2001 – 2006: Hamamatsu University School of Medicine, Assistant Professor, 医学部, 助手 2004: Hamamatsu University School of Medicine, Assistant Professor, 医学部, 助手 1998 – 2000: 産業医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Functional biochemistry / Biological Sciences / Hygiene / Basic Section 50010:Tumor biology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Biological Sciences / Functional biochemistry / Molecular biology / Tumor biology … More / Digestive surgery / Functional biochemistry / Hygiene / General medical chemistry Less
Keywords	Principal Investigator p27 / タンパク分解 / 癌 / Skp2 / p27Kip1 / Fbw7 / Pirh2 / 分子生物学 / 胃がん / スキルス胃がん … More / オルガノイド / 造血障害 / 血球細胞分化 / 鉄過剰 / 貧血 / 鉄剤 / 造血幹細胞 / GATA2 / CXCL13 / 血球細胞 / c-Myb / 炎症 / metastasis / invasion / がん / 転移 / 浸潤 / 浸潤転移 / intracellular signaling / cell cycle / colorectal carcinoma / ubiquitin / 癌抑制遺伝子産物 / プロテアソーム / 細胞周期 / 大腸癌 / ユビキチン / T cell / 蛋白分解 / T 細胞分化 / GATA3 / タナパク分解 / ユビキチン化 / GPR / 予後 / p27^<Kip1> / ジーンターゲッティング / 遺伝子多型 / CYP2A6 / ニコチン / ジーンターゲティング / アルデヒド脱水素酵素 / ノックアウトマウス … More Except Principal Investigator 細胞周期 / ユビキチン / p27^<Kip1> / RBタンパク質 / プロテアソーム / 癌 / Skp2 / Cell cycle / p27 / 癌抑制遺伝子産物 / 予後 / RB / cancer / RB protein / prognosis / Ubiquitin ligase / ユビキチンリガーゼ / 発がん / p53 / p27Kip1 / ジーンターゲッティング / 染色体構築・機能・分配 / X染色体不活性化 / 相同組換え / ノンコーディングRNA / lncRNA / gastric cancer / colon cancer / 消化器癌 / ubiquitin / Mdm2 / 癌化 / Gene therapy / リン酸化 / ユビキチン-プロテアソーム / p27^<kip1> / 遺伝子治療 / Environmental Chemicals / Ethanol / Acetaldehyde / Alcohol preference / Genetic Polymorphism / Alcohol / Knockout mice / Acetaldehyde dehydrogenase / 内因性オピオイド / 食道癌 / Cytochrome P450 2E1 / エタノール嗜好性 / アルコール / 遺伝子多型 / 環境中化学物質 / アセトアルデヒド / アルコール嗜好性 / Cytochrome P450 / アルデヒド脱水素酵素 / ノックアウトマウス / サイクリン / タンパク質分解 / 大腸癌 / Cks1 / p27^<Kipl> Less

ゲノム編集オルガノイド由来プレクリニカルモデルによるスキルス胃がん発生進展の解明Principal Investigator
- Principal Investigator
  
  北川恭子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  University of Miyazaki
Study of the health effects of long-term iron use with a focus on impaired blood cell differentiation.Principal Investigator
- Principal Investigator
  
  Kitagawa Kyoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kanazawa University
  University of Occupational and Environmental Health, Japan
Regulatory mechanism of homologous recombination in a Sex-chromosome-dependent manner
- Principal Investigator
  
  Kitagawa Masatoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Hamamatsu University School of Medicine
Regulation of inflammatory response via ubiquitin-dependent degradation by Fbw7Principal Investigator
- Principal Investigator
  
  KITAGAWA KYOKO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hamamatsu University School of Medicine
Long non-coding RNA associated with cancer stemness
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Hamamatsu University School of Medicine
Analysis of the novel function of SCF-Fbw7Principal Investigator
- Principal Investigator
  
  KITAGAWA Kyoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hamamatsu University School of Medicine
The analysis of the correlation between the increase of Pirh2 expression and cancer progressPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Kyoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hamamatsu University School of Medicine
p53制御分子Pirh2の新規ユビキチン化標的を介したがん化への寄与Principal Investigator
- Principal Investigator
  
  北川恭子
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
Evaluation of GPR48 as a novel molecular target which is involved in the tumor progressionPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Kyoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hamamatsu University School of Medicine
p53制御分子Pirh2の新たなユビキチン化標的分子とがん化との関連
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
個体レベルでの細胞周期のリアルタイムイメージングの試み
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Hamamatsu University School of Medicine
Analysis of p27 responsive gene as a novel molecular therapeutic targetPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Kyoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hamamatsu University School of Medicine
p27^<Kip1>の発現量低下を伴う予後不良の癌の分子標的の同定
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
RBファミリータンパク質のリン酸化と分解を介した細胞周期制御機構
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
Regulation of tumor suppressor RB pathway via ubiquitin system.
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hamamatsu University School of Medicine
Roles of P27/Skp2 pathway and identification of target genes on tumor malignancy of colon cancer
- Principal Investigator
  
  KAMIYA Kinji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hamamatsu University School of Medicine
p27Kip1の発現量低下を伴う予後不良の癌における悪性形質の形成機構
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
Identification of genes associated with poor prognosisPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Kyoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hamamatsu University School of Medicine
p27^<kip1>の発現量低下による予後不良の癌形質の形成メカニズムの研究
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
RBタンパク質のリン酸化と分解を介した標的遺伝子選択的制御機構
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
Accelerated degradation of tumor suppressor gene products in human cancers
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
p27^<kip1>のコンデショナルノックアウトによるヒト腫瘍の悪性化の解析
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
癌関連細胞周期調節遺伝子のソマティックノックアウト細胞の作成とその解析Principal Investigator
- Principal Investigator
  
  北川恭子
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hamamatsu University School of Medicine
チトクロムP450(CTP)2A6遺伝子多型が喫煙者の健康に及ぼす影響Principal Investigator
- Principal Investigator
  
  北川恭子
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hygiene
- Research Institution
  Hamamatsu University School of Medicine
  University of Occupational and Environmental Health, Japan
Application of ubiquitin ligase against tumor suppressor gene products for cancer therapy
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hamamatsu University School of Medicine
A study about individual sensitivity to environmental chemicals using acetaldehyde dehydrogenase 2 knockout mice
- Principal Investigator
  
  KAWAMOTO Toshihiro
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  University of Occupational and Environmental Health
ジーンターゲティング法を用いたアルデヒト脱水素酵素(aldh)2次損マウスの作成Principal Investigator
- Principal Investigator
  
  北川恭子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hygiene
- Research Institution
  University of Occupational and Environmental Health, Japan

[Book] ユビキチン-ブロテアソーム系とオートファジー(田中啓二・大隅良典編)2006
- Author(s)
  北川雅敏(分担執筆)
- Total Pages
  434
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590056
[Book] 細胞周期集中マスター2006
- Author(s)
  北川雅敏 (編者)
- Total Pages
  154
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590056
[Book] ユビキチン-プロテアソーム糸とオートファジー(田中啓二, 大隅良典編)2006
- Author(s)
  北川雅敏 (分担執筆)
- Total Pages
  434
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17590056
[Book] ユビキチン-フロテアソーム糸とオートファジー(田中啓二・大隅良典編)2006
- Author(s)
  北川雅敏 (分担執筆)
- Total Pages
  434
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17659079
[Book] 細胞周期集中マスター2006
- Author(s)
  北川雅敏 (編者)
- Total Pages
  154
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17659079
[Book] キーワードで理解する細胞周期イラストマップ2005
- Author(s)
  北川雅敏(編集中山敬一)
- Total Pages
  189
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16591308
[Book] キーワードで理解する細胞周期イラストマップ2005
- Author(s)
  北川雅敏(編集中山敬一)
- Total Pages
  189
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590058
[Book] キーワードで理解する細胞周期イラストマップ(編集中山敬一)2005
- Author(s)
  北川雅敏
- Total Pages
  189
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15590058
[Book] キーワードで理解する細胞周期イラストマップ(中山敬一編)2005
- Author(s)
  北川雅敏(分担執筆)
- Total Pages
  190
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16026214
[Book] キーワードで理解する細胞周期イラストマップ(中山敬一編)2005
- Author(s)
  北川雅敏(分担執筆)
- Total Pages
  190
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370060
[Book] キーワードで理解する細胞周期イラストマップ(中山敬一編)2005
- Author(s)
  北川雅敏(分担執筆)
- Total Pages
  190
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17659079
[Book] キーワードで理解する細胞周期イラストマップ(中山敬一編)2005
- Author(s)
  北川雅敏(分担執筆)
- Total Pages
  190
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17013037
[Book] キーワードで理解する細胞周期イラストマップ2005
- Author(s)
  北川雅敏(編集中山敬一)
- Total Pages
  189
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16021220
[Book] キーワードで理解する細胞周期イラストマップ(編集中山敬一)2005
- Author(s)
  北川雅敏
- Total Pages
  189
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16370060
[Book] キーワードで理解する細胞周期イラストマップ2005
- Author(s)
  北川雅敏(編集中山敬一)
- Total Pages
  189
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16026214
[Journal Article] Measurement of Bisphenol A Diglycidyl Ether (BADGE), BADGE derivatives, and Bisphenol F Diglycidyl Ether (BFDGE) in Japanese infants with NICU hospitalization history2024
- Author(s)
  Kuwamura Mami、Tanaka Kentaro、Onoda Atsuto、Taki Kentaro、Koriyama Chihaya、Kitagawa Kyoko、Kawamoto Toshihiro、Tsuji Mayumi
- Journal Title
  
  BMC Pediatrics
  
  Volume: 24 Issue: 1 Pages: 26-26
- DOI
  10.1186/s12887-023-04493-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18403, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-23K24593
[Journal Article] p130RB2 positively contributes to ATR activation in response to replication stress via the RPA32-ETAA1 axis2023
- Author(s)
  Uchida Chiharu、Niida Hiroyuki、Sakai Satoshi、Iijima Kenta、Kitagawa Kyoko、Ohhata Tatsuya、Shiotani Bunsyo、Kitagawa Masatoshi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 1870 Issue: 6 Pages: 119484-119484
- DOI
  10.1016/j.bbamcr.2023.119484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-20K07614, KAKENHI-PROJECT-23K24999
[Journal Article] The quantity and quality of scientific evidence about the health of working women in occupational health of Japan: A scoping review2023
- Author(s)
  Nomura Kyoko、Kitagawa Kyoko、Tsuji Mayumi、Iida Miho、Aoki Mizuki、Miyauchi Kasane、Hirayama Junko、Nagashima Kengo、Takebayashi Toru、Tsutsumi Akizumi
- Journal Title
  
  Journal of Occupational Health
  
  Volume: 65 Issue: 1 Pages: n/a
- DOI
  10.1002/1348-9585.12427
- ISSN
  1341-9145, 1348-9585
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-21H03192
[Journal Article] Subacute exposure to bisphenol F diglycidyl-ether induces chronic dermatitis characterized by psoriasis-like skin inflammation in mice.2023
- Author(s)
  Kitagawa K, Shibata E, Yamamoto M, Harada H, Yoshino K, Iwashita T, Oshima M, Tsuji M
- Journal Title
  
  Genes Cells.
  
  Volume: 28 Issue: 1 Pages: 42-52
- DOI
  10.1111/gtc.12995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06947, KAKENHI-PROJECT-20K07043
[Journal Article] Dynamics of transcription-mediated conversion from euchromatin to facultative heterochromatin at the Xist promoter by Tsix2021
- Author(s)
  Ohhata Tatsuya、Yamazawa Kazuki、Miura-Kamio Asuka、Takahashi Saori、Sakai Satoshi、Tamura Yuka、Uchida Chiharu、Kitagawa Kyoko、Niida Hiroyuki、Hiratani Ichiro、Kobayashi Hisato、Kimura Hiroshi、Wutz Anton、Kitagawa Masatoshi
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 13 Pages: 108912-108912
- DOI
  10.1016/j.celrep.2021.108912
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20582, KAKENHI-PLANNED-18H05527, KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18K14681, KAKENHI-PROJECT-17K08727, KAKENHI-PROJECT-19H03628, KAKENHI-PROJECT-20K07043, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-20K06541
[Journal Article] Substitution of Thr572 to Ala in mouse c-Myb attenuates progression of early erythroid differentiation.2020
- Author(s)
  3.Kitagawa K, Uchida C, Horiguchi R, Ohhata T, Sakai S, Niida H, Yasumoto S, Handa Y, Suzuki M, Hashimoto M, Tazawa T, Yokochi Y, Tsuji M, Kitagawa M.
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Issue: 1 Pages: 14381-14381
- DOI
  10.1038/s41598-020-71267-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07308, KAKENHI-PROJECT-20K07043
[Journal Article] Long noncoding RNA ELIT-1 acts as a Smad3 cofactor to facilitate TGF-β/Smad signaling and promote epithelial-mesenchymal transition.2019
- Author(s)
  Sakai, S., Ohhata, T., Kitagawa, K., Uchida, C., Aoshima, T., Niida, H., Suzuki, T., Inoue, Y., Miyazawa, K. and Kitagawa, M.
- Journal Title
  
  Cancer Res.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06994
[Journal Article] Inhibiting Skp2 E3 Ligase Suppresses Bleomycin-Induced Pulmonary Fibrosis.2018
- Author(s)
  Mikamo M, Kitagawa K, Sakai S, Uchida C, Ohhata T, Nishimoto K7,8, Niida H9, Suzuki S, Nakayama KI, Inui N, Suda T, Kitagawa M
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 (2) Issue: 2 Pages: 474-474
- DOI
  10.3390/ijms19020474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06994, KAKENHI-PROJECT-17K08727
[Journal Article] Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair2017
- Author(s)
  Niida, H., Matsunuma, R., Horiguchi, R., Uchida, C., Nakazawa, Y., Motegi, A., Nishimoto, K., Sakai, S., Ohhata, T., Kitagawa, K., Moriwaki, S., Nishitani, H., Ui, A., Ogi, T. and Kitagawa, M.
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 16102-16102
- DOI
  10.1038/ncomms16102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06994, KAKENHI-PROJECT-16K08580, KAKENHI-PROJECT-17K00548, KAKENHI-PROJECT-17K19615
[Journal Article] Homeobox Transcription Factor NKX2-1 Promotes Cyclin D1 Transcription in Lung Adenocarcinomas.2017
- Author(s)
  Harada M, Sakai S, Ohhata T, Kitagawa K, Mikamo M, Nishimoto K, Uchida C, Niida H, Kotake Y, Sugimura H, Suda T, Kitagawa M.
- Journal Title
  
  Mol. Cancer Res.
  
  Volume: 15(10) Pages: 1388-1397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06994
[Journal Article] Tenascin C in colorectal cancer stroma is a predictive marker for liver metastasis and is a potent target of miR-198 as identified by microRNA analysis.2017
- Author(s)
  Murakami, T., Kikuchi, H., Ishimatsu, H., Iino, I., Hirotsu, A., Matsumoto, T., Ozaki, Y., Kawabata, T., Hiramatsu, Y., Ohta, M., Kamiya, K., Fukushima, M., Baba, S., Kitagawa, K., Kitagawa, M. and Konno H
- Journal Title
  
  Br J Cancer.
  
  Volume: 117(9) Issue: 9 Pages: 1360-1370
- DOI
  10.1038/bjc.2017.291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06994, KAKENHI-PROJECT-15K10132
[Journal Article] Long non-coding RNA, PANDA, contributes to the stabilization of p53 tumor suppressor protein.2016
- Author(s)
  Kotake, Y., Kitagawa, K., Ohhata, T., Sakai, S., Uchida, C., Niida, H., Naemura, M. and Kitagawa, M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Issue: 1 Pages: 1605-1611
- DOI
  10.21873/anticanres.11292
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06994
[Journal Article] Oncogenic Ras influences the expression of multiple lncRNAs.2016
- Author(s)
  Kotake Y, Naemura M, Kitagawa K, Niida H, Tsunoda T, Shirasawa S, Kitagawa M.
- Journal Title
  
  Cytotechnology
  
  Volume: 68 Issue: 4 Pages: 1591-1596
- DOI
  10.1007/s10616-014-9834-9
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430127, KAKENHI-PROJECT-15K06994
[Journal Article] The SCF-type E3 ubiquitin ligases as cancer targets.2016
- Author(s)
  Kitagawa, K. and Kitagawa, M.
- Journal Title
  
  Curr. Cancer Drug Targets
  
  Volume: 16 Issue: 2 Pages: 119-29
- DOI
  10.2174/1568009616666151112122231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06994
[Journal Article] Long Non-coding RNA, PANDA, Contributes to the Stabilization of p53 Tumor Suppressor Protein.2016
- Author(s)
  Kotake Y, Kitagawa K, Ohhata T, Sakai S, Uchida C, Niida H, Naemura M, Kitagawa M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Pages: 1605-1611
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26640073
[Journal Article] Roles of defective ALDH2 polymorphism on liver protection and cancer development.2016
- Author(s)
  Matsumoto A, Thompson DC, Chen Y, Kitagawa K and Vasiliou V.
- Journal Title
  
  Environ Health Prev Med.
  
  Volume: 21 Issue: 6 Pages: 395-402
- DOI
  10.1007/s12199-016-0579-2
- NAID
  50010159078
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870515, KAKENHI-PROJECT-15K06994
[Journal Article] Regulation of GATA binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of Thr176 in GATA binding protein 2.2015
- Author(s)
  Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama K-I, Masumoto K, Katou F, Niida H, Kitagawa M
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 16 Pages: 10368-10381
- DOI
  10.1074/jbc.m114.613018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25860241, KAKENHI-PROJECT-15K06994
[Journal Article] Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development2014
- Author(s)
  Kitagawa, K., Shibata, K., Matsumoto, A., Matsumoto, M., Ohhata, T., Nakayama, K. I., Niida, H., Kitagawa, M.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 34 Issue: 14 Pages: 2732-2744
- DOI
  10.1128/mcb.01549-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-24570151, KAKENHI-PUBLICLY-25112508
[Journal Article] YB1 binds to and represses the p16 tumor suppressor gene.2013
- Author(s)
  Kotake Y, Ozawa Y, Harada M, Kitagawa K, Niida H, Morita Y, Tanaka K, Suda T, Kitagawa M.
- Journal Title
  
  Genes Cells.
  
  Volume: 11 Issue: 11 Pages: 999-1006
- DOI
  10.1111/gtc.12093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390072, KAKENHI-PROJECT-24570151, KAKENHI-PROJECT-24659130, KAKENHI-PUBLICLY-25112508, KAKENHI-PROJECT-25290044
[Journal Article] Cell cycle regulation by long non-coding RNAs.2013
- Author(s)
  Kitagawa M, Kitagawa K, Kotake Y, Niida H, Ohhata T.
- Journal Title
  
  Cell Mol Life Sci.
  
  Volume: 24 Issue: 24 Pages: 4785-4794
- DOI
  10.1007/s00018-013-1423-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390072, KAKENHI-PROJECT-24570151, KAKENHI-PROJECT-24659130, KAKENHI-PROJECT-24700975, KAKENHI-PUBLICLY-25112508, KAKENHI-PROJECT-25290044
[Journal Article] Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis2012
- Author(s)
  Hoshi H, Hao W, Fujita Y, Funayama A, Miyauchi Y, Hashimoto K, Miyamoto K, (他21名)
- Journal Title
  
  J. Bone Miner Res
  
  Volume: 27(9) Issue: 9 Pages: 2015-2023
- DOI
  10.1002/jbmr.1634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300257, KAKENHI-PROJECT-23390217, KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24500882, KAKENHI-PROJECT-24570151, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24651055, KAKENHI-PROJECT-24659395, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-24792252
[Journal Article] Decreased tonic inhibition in cerebellar granule cells causes motor dysfunction in a mouse model of Angelman syndrome.2012
- Author(s)
  Egawa, K., et al.
- Journal Title
  
  Sci. Transl. Med.
  
  Volume: 4 Issue: 163
- DOI
  10.1126/scitranslmed.3004655
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057005, KAKENHI-PROJECT-22300329, KAKENHI-PROJECT-23500413, KAKENHI-PROJECT-24570151, KAKENHI-PROJECT-24659130, KAKENHI-PROJECT-24659508
[Journal Article] The SCF ubiquitin ligases involved in hematopoietic lineage.2012
- Author(s)
  Kitagawa K. and Kitagawa M.
- Journal Title
  
  Curr. Drug Targets
  
  Volume: 13 Pages: 641-648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570151
[Journal Article] Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15^<INK4B> tumor suppressor gene2011
- Author(s)
  Kotake, Y., Nakagawa, T., Kitagawa, K., Suzuki, S., Liu, N., Kitagawa, M. and Xiong, Y.
- Journal Title
  
  Oncogene
  
  Volume: 30(16) Pages: 1956-62
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] GSK3 regulates the expression of human and mouse c-Myb via different mechanisms2010
- Author(s)
  Kitagawa, K., Kotake, Y., Hiramatsu, Y., Liu, N., Suzuki, S., Nakamura, S., Kikuchi, A. and Kitagawa, M.
- Journal Title
  
  Cell Div
  
  Volume: 5(27)
- NAID
  120005305355
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Formation of acetaldehyde-derived DNA adducts due to alcohol exposure2010
- Author(s)
  Yu, Hs., Oyama, T., Isse, T., Kitagawa, K., Pham, T. T., Tanaka, M. and Kawamoto, T.
- Journal Title
  
  Chem Biol Interact
  
  Volume: 188(3) Pages: 367-75
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Reduction of transforming growth factor-beta type II receptor is caused by the enhanced ubiquitin-dependent degradation in human renal cell carcinoma2010
- Author(s)
  Fukasawa, H., Yamamoto, T., Fujigaki, Y., Misaki, T., Ohashi, N., Takayama, T., Suzuki, S., Mugiya, S., Oda, T., Uchida, C., Kitagawa, K., Hattori, T., Hayashi, H., Ozono, S., Kitagawa, M. and Hishida, A.
- Journal Title
  
  Int J Cancer
  
  Volume: 127 Pages: 1517-25
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression : Role of protein phosphatases2010
- Author(s)
  Ma, H., Yu, L., Byra, EA., Hu, N., Kitagawa, K., Nakayama, KI., Kawamoto, T and Ren, J.
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 49(2) Pages: 322-9
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] GSK3 regulates the expression of human and mouse c-Myb via different mechanisms.2010
- Author(s)
  Kitagawa, K., et al.
- Journal Title
  
  Cell Division
  
  Volume: 5 Pages: 1-10
- NAID
  120005305355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Adenovirus E1A inhibits SCF^<Fbw7> ubiquitin ligase2009
- Author(s)
  Isobe, T., Hattori, T., Kitagawa, K., Uchida, C., Kotake, Y., Kosugi, I., Oda, T. and Kitagawa, M.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 284 Pages: 27766-79
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Fbw7 promotes ubiquitin-dependent degradation of c-Myb : involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.2009
- Author(s)
  Kitagawa, K., et al.
- Journal Title
  
  Oncogene 28
  
  Pages: 2393-2405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012022
[Journal Article] Ubiquitin-mediated control of oncogene and tumor suppressor geneproducts2009
- Author(s)
  Kitagawa, K., et al.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1374-81
- NAID
  10027192844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers2009
- Author(s)
  Shimada, M., Kitagawa, K., Dobashi, Y., Isobe, T., Hattori, T., Uchida, C., Abe, K., Kotake, Y., Oda, T., Suzuki, H., Hashimoto, K. and Kitagawa, M.
- Journal Title
  
  Cancer Sci
  
  Volume: 100(5) Pages: 866-72
- NAID
  10025145601
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Cholinergic alterations following alcohol exposure in the frontal cortex of Aldh2-deficient mice models2009
- Author(s)
  Jamal, M., Ameno, K., Miki, T., Wang, W., Kumihashi, M., Isse, T, Kawamoto, T., Kitagawa, K, , Nakayama, K., Ijiri, I and Kinoshita, H.
- Journal Title
  
  Brain Res
  
  Volume: 1295 Pages: 37-43
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Fbw7 promotes ubiquitin-dependent degradation of c-Myb : involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb2009
- Author(s)
  Kitagawa, K., et al.
- Journal Title
  
  Oncogene 28
  
  Pages: 2393-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Fbw7 promotes ubiquitin-dependent degradation of c-Myb : involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb2009
- Author(s)
  Kitagawa, K., Hiramatsu, Y., Uchida, C., Isobe, T., Hattori, T., Oda, T., Shibata, K., Nakamura, S., Kikuchi, A. and Kitagawa, M.
- Journal Title
  
  Oncogene
  
  Volume: 28(25) Pages: 2393-405
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Characteristics of aldehyde dehydrogenase 2(Aldh2) knockout mice2009
- Author(s)
  Yu, HS, Oyama, T, Isse, T, Kitagawa, K., Ogawa, M., Pham, T. T. and Kawamoto, T.
- Journal Title
  
  Toxicol. Mechanisms and Methods
  
  Volume: 19(9) Pages: 535-40
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Ubiquitin-mediated control of oncogene and tumor suppressor gene products2009
- Author(s)
  Kitagawa, K., Kotake, Y. and Kitagawa, M.
- Journal Title
  
  Cancer Sci
  
  Volume: 100(8) Pages: 1374-81
- NAID
  10027192844
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Ubiquitin-mediated control of oncogene and tumor suppressor gene products.2009
- Author(s)
  Kitagawa, K., et al.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1374-1381
- NAID
  10027192844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012022
[Journal Article] Decrease in TRADD resulted from ubiquitin-dependent degradation in the obstructive renal injury in rats. Am2009
- Author(s)
  Misaki, T., Yamamoto, T., Suzuki, S., Fukasawa, H., Togawa, A., Ohashi, N., Suzuki, H., Fujigaki, Y., Oda, T., Uchida, C., Kitagawa, K., Hattori, T., Kitagawa, M. and Hishida, A.
- Journal Title
  
  J. Pathol
  
  Volume: 175(1) Pages: 74-83
- Data Source
  KAKENHI-PROJECT-21590062
[Journal Article] Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells2008
- Author(s)
  Kurata, K, Yanagisawa, R., Ohira, M. Kitagawa, M, Nakagawara, A, Kamijo, T.
- Journal Title
  
  Oncogene 27
  
  Pages: 741-754
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] TSU68 prevents liver metastasis of colon cancer xenografts by modulating the pre-metastatic niche2008
- Author(s)
  Yamamoto, M, Kikuchi, H, Ohta, M, Kawabata, T, Hiramatsu, Y, Kondo, K, Baba, M, Kamiya, K, Tanaka, T, Kitagawa and M. Konno H.
- Journal Title
  
  Cancer Res 68
  
  Pages: 9754-9762
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Regulation of TGF-beta signaling by Smads and its roles in tissue fibrosis2008
- Author(s)
  Fukasawa, H. Yamamato, T. Kitagawa, M. and Hishida A.
- Journal Title
  
  Current signal transduction therapy 3
  
  Pages: 1-6
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Increased frequencies of micronucleated reticulocytes and T-cell receptor mutation in Aldh2 knockout mice exposed to acetaldehyde2008
- Author(s)
  Kunugita, N, Isse, T, Oyama, T, Kitagawa, K, Ogawa, M, Yamaguchi,T, Kinaga, T,and Kawamoto, T.
- Journal Title
  
  J.Toxicol. Sci 33(1)
  
  Pages: 31-6
- NAID
  110006596029
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF^<FWD1/b-TrCP>-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD12008
- Author(s)
  Hayakawa, M, Matsushima, M, Hagiwara, H, Oshima, T, Fujino, T, Ando, K, Kikugawa, K, Tanaka, H, Miyazawa,K.and Kitagawa, M.
- Journal Title
  
  Genes to Cells 13
  
  Pages: 329-442
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Intrarenal RAS activity and urinary angiotensinogen excretion in anti-thymocyte serum nephritis rats2008
- Author(s)
  Ohashi, N, Yamamoto, T, Huang, Y, Misaki, T, Fukasawa, H, Suzuki, H, Togawa, A, Suzuki, S, Fujigaki, Y, Nakagawa, T, Nakamura, Y, Suzuki, F, Kitagawa, M, Hishida, A.
- Journal Title
  
  Am J.Physiol Renal Physiol 295
  
  Pages: 1512-1518
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Effects of 5-week ethanol feeding on the liver of aldehyde dehydrogenase 2 knockout mice2008
- Author(s)
  Matsumoto, A, Kawamoto, T, Mutoh,F, Isse, T, Oyama, T, Kitagawa, K, Nakayama, K.-i.and Ichiba, M.
- Journal Title
  
  Pharmacogenet Genomics 18(10)
  
  Pages: 847-52
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit2008
- Author(s)
  Abe, K, Hattori, T, Isobe, T, Kitagawa, K, Oda, T, Uchida, C.and Kitagawa, M.
- Journal Title
  
  Biomed Res 29
  
  Pages: 53-60
- NAID
  130004470702
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Contribution of Extracellular Signal-Regulated Kinases to the IL-1-induced Growth Inhibition of Human Melanoma Cells A3752007
- Author(s)
  Arakawa, T, Yamamura, T, Hattori, T, Hayashi H, Mori, A, Yoshida, A, Uchida, C, Kitagawa, M, and Onozaki, K.
- Journal Title
  
  International Immunopharmacology 8
  
  Pages: 80-89
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Reproductive Toxicity of Ethylene Glycol Monoethyl Ether in Aldh2 Knockout Mice2007
- Author(s)
  Wang, R.S, Ohtani, K, Suda, M, Kitagawa, K, Nakayama, K.-I, Kawamoto, T,and Nakajima, T.
- Journal Title
  
  Industrial Health 45(4)
  
  Pages: 574-578
- NAID
  130004828493
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Increased formation of hepaticN2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2 knockout mice treated with ethanol2007
- Author(s)
  Matsuda, T, Matsumoto, A, Uchida, M, Kanaly, R., Misaki, K, Shibutani, S, Kawamoto, T, Kitagawa, K, Nakayama, K.-I, Tomokuni, K,and Ichiba, M.
- Journal Title
  
  Carcinogenesis 28(11)
  
  Pages: 2363-2366
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells2007
- Author(s)
  Kikuchi, H, Uchida, C, Hattori, T, Isobe, T, Hiramatsu, Y, Kitagawa, K, Oda, T, Konno, H,and Kitagawa, M.
- Journal Title
  
  Carcinogenesis 28
  
  Pages: 1752-1758
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Cys-881 is essential for the trafficking and secretion of truncated mutant ceruloplasmin in aceruloplasminemia2007
- Author(s)
  Kono, S, Suzuki, H, Oda, T, Takahashi, Y, Shirakawa, K, Takahashi, Y, Kitagawa, M,and Miyajima, H.
- Journal Title
  
  J. Hepatology 47
  
  Pages: 844-850
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites2007
- Author(s)
  Li, S, Gao, Y, Tokuyama, T, Yamamoto, J, Yokota, N, Yamamoto, S, Terakawa, S, Kitagawa, M,and Namba, H.
- Journal Title
  
  Cancer Letters 251(2)
  
  Pages: 220-227
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Effect of loss of heterozygosity of the c-kit gene on prognosis after hepatectomy for metastatic liver gastrointestinal stromal tumors2007
- Author(s)
  Kikuchi, H, Yamamoto, M, Hiramatsu, Y, Baba, M, Ohta, M, Kamiya, K, Tanaka, T, Suzuki, S, Sugimura, H, Kitagawa, M, Kanai, T, Kitayama, Y, Kanda, T, Nishikura, K,and Konno, H.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1734-1739
- NAID
  10020119012
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice2007
- Author(s)
  Suzuki, S, Fukasawa, H, Kitagawa, K, Uchida, C, Hattori, T, Isobe, T, Oda, T, Misaki, T, Ohashi, N, Nakayama, K, Nakayama, K.I., Hishida, A., Yamamoto, T,and Kitagawa, M.
- Journal Title
  
  Am.J.Pathol 171
  
  Pages: 473-483
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Critical and functional regulation of CHOP(C/EBP homologous protein)through the N-terminal portion2007
- Author(s)
  Ohoka, N, Hattori, T, Kitagawa, M, Onozaki, K,and Hayashi H.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 35687-35694
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Pirh2 Promotes Ubiquitin-Dependent Degradation of the CDK Inhibitor p27Kip12007
- Author(s)
  Hattori, T, Isobe, T, Abe, K, Kikuchi, H, Kitagawa, K, Oda, T, Uchida, C,and Kitagawa, M.
- Journal Title
  
  Cancer Research 67
  
  Pages: 10789-10795
- Data Source
  KAKENHI-PROJECT-19590064
[Journal Article] Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage2007
- Author(s)
  Inoue, Y, Kitagawa, M,and Taya, Y.
- Journal Title
  
  EMBO J 26
  
  Pages: 2083-2093
- Data Source
  KAKENHI-PROJECT-19590064
[Patent] 癌治療用組成物2012
- Inventor(s)
  北川雅敏、高芸、北川恭子
- Industrial Property Rights Holder
  浜松医科大学
- Industrial Property Number
  2007-528119
- Acquisition Date
  2012-02-16
- Data Source
  KAKENHI-PROJECT-21590062
[Patent] 癌の転移性及び浸潤能の検査方法2006
- Inventor(s)
  北川雅敏、高芸、北川恭子
- Industrial Property Rights Holder
  浜松医科大学
- Acquisition Date
  2006-04-14
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] ビスフェノールFジグリシジルエーテル (BFDGE)ばく露による健康障害リスクの検討2023
- Author(s)
  北川恭子　桑村真美　櫻木俊秀　辻真弓
- Organizer
  第93回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07043
[Presentation] ブレオマイシンで誘発した肺線維症の進行におけるSkp2の関与2021
- Author(s)
  北川恭子　美甘真史　辻真弓　北川雅敏
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07043
[Presentation] オンライン型産業医学実習の成果2021
- Author(s)
  田中里枝　北川恭子　辻真弓
- Organizer
  第39回産業医科大学学会
- Data Source
  KAKENHI-PROJECT-20K07043
[Presentation] 福岡県某クリニックにおける新型コロナウイルス感染症診療体制とその実際2021
- Author(s)
  山口優子　小山倫太郎　山口哲右　小山倫浩　田中里枝　北川恭子　辻真弓
- Organizer
  第94回日本産業衛生学会
- Data Source
  KAKENHI-PROJECT-20K07043
[Presentation] マウス赤血球の初期分化の遅延をもたらした転写因子c-Myb Thr572のアミノ酸置換2020
- Author(s)
  北川恭子　内田千晴　辻真弓北川雅敏
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07043
[Presentation] 赤血球初期分化時のc-Myb発現量調節の役割2020
- Author(s)
  北川恭子　辻真弓　北川雅敏
- Organizer
  第90回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07043
[Presentation] ブレオマイシン誘導性肺線維症モデルマウスにおいてユビキチンE3 リガーゼ Skp2の阻害は症状を軽減する2018
- Author(s)
  北川恭子　美甘真史　北川雅敏
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06994
[Presentation] SCF-type E3 ligase Fbw7 plays pivotal roles in the maintenance of the development and commitment in hematopoietic cells.2016
- Author(s)
  Kyoko Kitagawa, Masatoshi Kitagawa
- Organizer
  The 5th JCA-AACR Special Joint Conference
- Place of Presentation
  Urayasu
- Year and Date
  2016-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06994
[Presentation] Behavioral anlysis of ALDH2 deficient mice.2016
- Author(s)
  Toru Hosoi, Kohei Mori, Kyoko Kitagawa, Koichiro Ozawa
- Organizer
  the 18th International Symposium of Society for Aldh2 Knockout Mouse Research
- Place of Presentation
  Kitakyushu
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06994
[Presentation] Fbw7による GATA2のユビキチン化分解機構2015
- Author(s)
  北川恭子　中嶋友美　北川雅敏
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06994
[Presentation] CDK1によるリン酸化に依存した GATA2のFbw7による分解2015
- Author(s)
  北川恭子　中嶋友美　北川雅敏
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06994
[Presentation] 癌抑制ユビキチンリガーゼFbw7の新規基質2013
- Author(s)
  北川雅敏　北川恭子
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] リン酸化とユビキチン化修飾による転写因子 GATA3タンパク質の安定性制御機構2013
- Author(s)
  北川恭子　北川雅敏
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] Analysis of the regulation of the stability of transcription factor GATA32013
- Author(s)
  北川恭子　柴田清　北川雅敏
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] Fbw7 contributes to regulation of T-cell development and targets GATA32013
- Author(s)
  北川恭子　柴田清　北川雅敏
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] リン酸化を介したGATA3転写因子の制御機構2012
- Author(s)
  北川恭子　中嶋友美　北川雅敏
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] 転写因子GATA3の安定性の制御に関わるリン酸化とユビキチン化修飾機構2012
- Author(s)
  北川恭子　松本雅記　北川雅敏
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] Skp2ノックアウトマウスで見られた腎障害の軽減はSkp2-p27ダブルノックアウトマウスで解除される2012
- Author(s)
  鈴木小由里　深澤洋敬　三崎太郎　戸川証　大橋温　北川恭子　神武洋二郎　Liu Ning　丹伊田浩行　山本龍夫　北川雅敏
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] 転写因子YB-1の新規標的遺伝子としてのCyclin D1 の解析と非小細胞肺癌における解析2012
- Author(s)
  原田雅教　神武洋二郎　鈴木小由里　大畑樹也　北川恭子　丹伊田浩行　北川雅敏
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] The epigenetic regulation of INK4 locus by Polycomb and long noncoding RNA, ANRIL2011
- Author(s)
  神武洋二郎,中川直,北川恭子,鈴木小由里,劉寧,丹伊田浩行, Yue Xiong,北川雅敏
- Organizer
  第34回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] 増殖分化制御因子のタンパク量調節機構の解析2011
- Author(s)
  北川恭子,　中村悟己,　北川雅敏
- Organizer
  第73回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] ヒトおよびマウスc-Mybタンパク量調節におけるGSK3βの異なる関与2011
- Author(s)
  北川恭子
- Organizer
  日本血液学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] 慢性進行性腎障害におけるCks1およびSkp2の発現亢進の意義2010
- Author(s)
  鈴木小由里,深沢洋敬,三崎太郎,戸川証,北川恭子,神武洋二郎,山本龍夫,北川雅敏
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] GSK3によるc-Mybの量的制御機構2010
- Author(s)
  北川恭子, 他
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] GSK3によるc-Mybの量的制御機構2010
- Author(s)
  北川恭子, 神武洋二郎, 北川雅敏
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] 増殖シグナルの新たな制御機構2010
- Author(s)
  北川雅敏, 他
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] c-Mybの量的制御機構におけるGSK3の関与2010
- Author(s)
  北川恭子, 他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] 癌抑制遺伝子産物Mig-6のリン酸化とその責任酵素の解析2010
- Author(s)
  Ning Liu,北川恭子,神武洋二郎,丹伊田浩行,北川雅敏
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] 転写因子c-Mybのユビキチン-プロテアソームシステムによる分解機構の解明2010
- Author(s)
  北川恭子, 神武洋二郎, 小田敏明, 北川雅敏
- Organizer
  日本薬学会第130年会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] A novel target and function of Chkl2010
- Author(s)
  Masatoshi Kitagawa
- Organizer
  MEXT Priority Research Project "Cell Proliferation Control" International Symposium Cell Cycle and Cell Differentiation From A to Z
- Place of Presentation
  名古屋
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] c-Mybの量的制御機構におけるGSK3の関与2010
- Author(s)
  北川恭子, 神武洋二郎, 北川雅敏
- Organizer
  第69回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] CUL4A-DDB1ユビキチンリガーゼとMLLヒストンメチルトランスフェラーゼは癌化シグナルによるP16転写活性化に必要である2010
- Author(s)
  神武洋二郎,北川恭子,北川雅敏
- Organizer
  第69回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] CUL4-DDB1/MLL complex activates the p16 transcription through histone H3K4 methylation2010
- Author(s)
  Yojiro Kotake、Xiong Yue, Kyoko Kitagawa, Masatoshi Kitagawa
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] 細胞老化誘導のキーレギュレーター、p16の転写制御機構の解明2010
- Author(s)
  神武洋二郎,北川恭子, Xiong Yue,北川雅敏
- Organizer
  日本農芸化学会2010年度大会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] SCF-Fbw7 E3 ligase targets c-Myb for GSK3-dependent degradation2009
- Author(s)
  北川恭子, 平松良浩, 磯部智康, 柴田清, 中村悟己, 北川雅敏
- Organizer
  第32回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] Regulation of c-Myb by Fbw7 via ubiquitin-proteasome-dependent degradation2009
- Author(s)
  北川恭子,　中村悟己,北川雅敏
- Organizer
  第71回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] エピジェネティックなp16転写制御機構2009
- Author(s)
  神武洋二郎,北川恭子,北川雅敏
- Organizer
  第68回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] Pirh2はp27のユビキチンリガーゼとしてヒトの癌の悪性度に関与する2009
- Author(s)
  北川雅敏,島田真衣,土橋洋,服部隆行,神武洋二郎,橋本賢二,北川恭子
- Organizer
  第68回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] Fbw7はGSK3によるリン酸化を介してc-Mybのユビキチン依存的分解を実行する2009
- Author(s)
  北川恭子, 中村悟己, 神武洋二郎, 北川雅敏
- Organizer
  第68回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21590062
[Presentation] GPR48による癌転移機構の解析2008
- Author(s)
  磯部智康, 島田真衣, 劉寧, 北川恭子, 鈴木小由里, 小田敏明, 服部隆行, 内田千晴, 北川雅敏
- Organizer
  第31回日本分子生物学会、第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590064
[Presentation] タンパク質過剰発現誘導性小胞体の構造と機能2008
- Author(s)
  小田敏明, 服部隆行, 磯部智康、北川恭子, 内田千晴, 横田貞記, 北川雅敏
- Organizer
  第31回日本分子生物学会、第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590064
[Presentation] Novel regulatory mechanisms of Cyclin Dl expression2007
- Author(s)
  Kitagawa, M., et. al.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590064
[Presentation] 細胞周期制御分子p27のユビキチン依存的分解機構と病態2007
- Author(s)
  北川雅敏
- Organizer
  第30回日本分子生物学会第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590064
[Presentation] 癌関連核内因子のユビキチン依存的制御機構2007
- Author(s)
  北川雅敏
- Organizer
  Nuclear Signaling JAPAN 2007シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19590064
[Presentation] 細胞周期制御分子p27のユビキチン依存的分解機構と病態2007
- Author(s)
  北川雅敏
- Organizer
  第30回日本分乎生物学会第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590064
[Presentation] Novel regulatory mechanisms of Cyclin D1 expression2007
- Author(s)
  Kitagawa, M, et.al.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590064
[Presentation] GATA3 is a novel target for an E3 ligase SCF-Fbw7 in T-cell development.
- Author(s)
  Masatoshi Kitagawa, Kyoko Kitagawa
- Organizer
  The FEBS EMBO 2014 Conference
- Place of Presentation
  Paris, France
- Year and Date
  2014-08-30 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] T 細胞分化過程におけるGATA3のFbw7依存的分解の分子機構
- Author(s)
  北川雅敏、北川恭子
- Organizer
  第87回日本生化学学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] Fbw7 targets GATA3 and contributes to regulation of T-cell development.
- Author(s)
  Kyoko Kitagawa, Masatoshi Kitagawa:
- Organizer
  FASEB Science Research Conferences, Ubiquitin and Cellylar Regulation 2014
- Place of Presentation
  Saxtons River, VT, USA
- Year and Date
  2014-06-15 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] Fbw7のT 細胞分化の制御における新規基質GATA3の分解の寄与
- Author(s)
  北川恭子　丹伊田浩行　北川雅敏
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24570151
[Presentation] T細胞分化過程におけるGATA3分解機構
- Author(s)
  北川恭子　柴田清　大畑樹也　丹伊田浩行　北川雅敏
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570151

1. KITAGAWA Masatoshi (50294971)

# of Collaborated Projects: 21 results

# of Collaborated Products: 89 results
2. UCHIDA Chiharu (60223567)

# of Collaborated Projects: 11 results

# of Collaborated Products: 1 results
3. ODA Toshiaki (90126805)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
4. HATTORI Takayuki (50377751)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OHHATA Tatsuya (80616459)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. NIIDA Hiroyuki (20336671)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. KAWAMOTO Toshihiro (60177748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUMOTO Akiko (10330979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. ISSE Toyohi (80341494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OYAMA Tsunihiro (00309965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAMIYA Kinji (20324361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KONNO Hiroyuki (00138033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 辻真弓 (40457601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. 小野田淳人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 平谷伊智朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 神武洋二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 岩下寿秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 峯岸直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KITAGAWA Kyoko 北川 恭子

Kitagawa Kyoko 北川 恭子

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ゲノム編集オルガノイド由来プレクリニカルモデルによるスキルス胃がん発生進展の解明Principal Investigator

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Study of the health effects of long-term iron use with a focus on impaired blood cell differentiation.Principal Investigator

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Regulation of inflammatory response via ubiquitin-dependent degradation by Fbw7Principal Investigator

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Analysis of the novel function of SCF-Fbw7Principal Investigator

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The analysis of the correlation between the increase of Pirh2 expression and cancer progressPrincipal Investigator

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p53制御分子Pirh2の新規ユビキチン化標的を介したがん化への寄与Principal Investigator

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Evaluation of GPR48 as a novel molecular target which is involved in the tumor progressionPrincipal Investigator

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Analysis of p27 responsive gene as a novel molecular therapeutic targetPrincipal Investigator

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KITAGAWA Kyoko 北川恭子

Kitagawa Kyoko 北川恭子