• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Shiiba Masashi  椎葉 正史

ORCIDConnect your ORCID iD *help
… Alternative Names

SHIIBA Masashi  椎葉 正史

椎葉 正史  シイバ マサシ

Less
Researcher Number 20301096
Other IDs
Affiliation (Current) 2023: 東京大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help 2016 – 2021: 千葉大学, 大学院医学研究院, 准教授
2012 – 2015: 千葉大学, 医学(系)研究科(研究院), 准教授
2012: 千葉大学, 大学院・医学研究院, 准教授
2009 – 2011: Chiba University, 医学部附属病院, 講師
2007 – 2009: 千葉大学, 大学院・医学研究院, 講師
2002 – 2004: 千葉大学, 大学院・医学研究院, 助手
1999: 千葉大学, 医学部・附属病院, 助手
Review Section/Research Field
Principal Investigator
Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Surgical dentistry / Basic Section 53030:Respiratory medicine-related
Keywords
Principal Investigator
口腔癌 / マイクロアレイ解析 / 口腔扁平上皮癌 / maspin / stathmin / long non coding RNA / miRNA / microRNA / 癌関連遺伝子 / micro RNA … More / 癌関連遣伝子 / アルドースケトース還元酵素 / 抗癌剤多剤耐性遺伝子 / アルドケトース還元酵素(AKR) / 抗癌剤耐性 / メフェナム酸 / アルドース‐ケトース還元酵素(AKR) / long non-cording RNA / long non-coding RNA / 発がん / がん遺伝子 / 浸潤・転移 / 腫瘍 / Aly/REF / 唾液腺癌 / 扁平上皮癌 / 遺伝子機能評価 / 庸平上皮癌 / マイクロアレイ / cDNA / 遺伝子発現プロファイリング / 腺癌 / 遺伝子クローニング / oral cancer / microarray analysis / salivary gland tumor / squamous cell carcinoma / pleomorphic adenoma / UCA1 / LINC00256A / 共培養 / 腫瘍の浸潤・転移能 / 放射線耐性試験 / 抗癌剤耐性試験 / 抗がん剤・放射線耐性 / 抗がん剤耐性試験 / lncRNA / スーパーエンハンサー / ChIP-seq 法 / 組織特異性 / 疾患特異性 / 機能特異性 / H3K27ac / エピジェネティックな修飾 / スーパーエンハンサー(SE) / Chip-seq法 / H3K27 … More
Except Principal Investigator
口腔癌 / DNA methylation / 口腔扁平上皮癌 / DNA methyltransferase / 舌癌 / 完全長cDNAライブラリー / ケラチン遺伝子 / 腫瘍拒絶抗原 / 扁平上皮癌 / ワクチン療法 / 養子免疫療法 / 免疫療法 / 臨床腫瘍学 / 低病原性ウイルス / ウイルスカプシド / 腫瘍特異的吸着 / リポソーム / 腫瘍特異性 / リボソーム / drug delivery system / シンドビスウイルス / MyoD family 遺伝子 / 脂肪幹細胞 / 筋再生 / MyoD family遺伝子 / methyltransferase / 細胞周期関連遺伝子 / 5-Aza-C / 腺癌 / CDKN2A / p16遺伝子 / APC遺伝子 / FEZ1遺伝子 / p73遺伝子 / oral squamous cell carcinoma / APC gene / p16 gene / FEZ1 gene / KAI1 gene / survivin / ノックアウトマウス / CRISPR/Cas9 / PLOD2 / LH2 / 胎生致死 / コラーゲンクロスリンク / HIF-1α / HIF1-α / 低酸素応答 / 転移モデル / GFP標識癌細胞 / Plod2 / クロスリンク解析 / ナノインデンテーション試験 / KOマウス / 扁平上皮がん / 肺扁平上皮がん / 口腔扁平上皮がん / 上皮間葉移行 / EPSTI1 / 口腔がん / 肺がん / 分子標的治療 / 頭頸部扁平上皮がん / 微小管阻害抗癌剤 / 頭頚部悪性腫瘍 / 化学療法 / 微小管阻害薬剤 / 薬剤耐性機構 / 克服薬 Less
  • Research Projects

    (15 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (23 People)
  •  Molecular analysis and overcoming of drug resistance to microtubule inhibitors

    • Principal Investigator
      伏見 一章
    • Project Period (FY)
      2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Chiba University
  •  CRISPRスクリーニング法を用いたセツキシマブ耐性分子機構の解明

    • Principal Investigator
      小池 一幸
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Chiba University
  •  Development of molecular targeted therapy for pulmonary squamous cell carcinoma

    • Principal Investigator
      瀧口 裕一
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Chiba University
  •  口腔癌悪性度を決定するスーパーエンハンサーによる系統的転写制御機構の解明Principal Investigator

    • Principal Investigator
      椎葉 正史
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Chiba University
  •  Evaluate changes in collagen cross-linking in lysyl hydroxylase 2 knockout mice and elucidate the role of PLOD2 in cancer metastasis

    • Principal Investigator
      Nakashima Dai
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Chiba University
  •  Development of novel therapy based on functions of long non coding RNA in the cancer and cancer-associated cellsPrincipal Investigator

    • Principal Investigator
      SHIIBA Masashi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Regeneration of muscle by introduction of MyoD family gene into adipose-derived stem cells

    • Principal Investigator
      SAKAMOTO Yousuke
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Control mechanism elucidation of the Wnt pathway, extracellular matrix by the CD82 and the development of cancer metastasis inhibitorPrincipal Investigator

    • Principal Investigator
      SHIIBA MASASHI
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Studies of the clinical significance and the role of long non coding RNA in oral cancer.Principal Investigator

    • Principal Investigator
      SHIIBA MASASHI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Development of enhancement chemotherapy by overcoming an anti-cancer resistant mechanism of AKR1C familyPrincipal Investigator

    • Principal Investigator
      SHIIBA Masashi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Functional analysis of microRNA in oral carcinoma.Principal Investigator

    • Principal Investigator
      SHIIBA Masashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Development of cancer-targeted liposome with viral proteins

    • Principal Investigator
      UZAWA Katsuhiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Search for oral cancer specific genes and molecular cloning using in-house cDNA microarayPrincipal Investigator

    • Principal Investigator
      SHIBA Masashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  Study on the role of DNA methyltransferases in regulation of the expression of genes associated with the control of cell cycle

    • Principal Investigator
      BUKAWA Hiroki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  腫瘍拒絶抗原分子による口腔癌の免疫療法の確立

    • Principal Investigator
      大越 基弘
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo

All 2020 2010 2009 2008

All Journal Article Presentation Patent

  • [Journal Article] Oncolytic activity of Sindbis virus in human oral squamous carcinoma cells2009

    • Author(s)
      Saito K, Uzawa K, Kasamatsu A, Shinozuka K, Sakuma K, Yamatoji M, Shiiba M, Shino Y, Shirasawa H, Tanzawa H
    • Journal Title

      Br J Cancer 101(4)

      Pages: 684-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390508
  • [Journal Article] Oncolytic virotherapy for oral squamous cell carcinoma using replication-competent viruses2009

    • Author(s)
      Saito K, Shirasawa H, Isegawa N, Shiiba M, Uzawa K, Tanzawa H
    • Journal Title

      Oral Oncology 45(12)

      Pages: 1021-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390508
  • [Patent] 腫瘍特異性を有する新型リポソーム2010

    • Inventor(s)
      鵜沢一弘, 齋藤謙悟, 丹沢秀樹, 白澤浩, 山本惠司, 森部久仁一, 椎葉正史
    • Industrial Property Rights Holder
      千葉大学
    • Industrial Property Number
      2010-086071
    • Filing Date
      2010-04-02
    • Data Source
      KAKENHI-PROJECT-19390508
  • [Presentation] Epithelial-stromal interaction 1 (EPSTI1) in human oral and lung squamous cell carcinomas2020

    • Author(s)
      Fan, M. Arai, M. Tawada, A. Chiba, T. Fukushima, R. Uzawa, K. Shiiba, M. Kato, N. Takiguchi, Y.
    • Organizer
      The 79th Annual Meeting of the Japanese Cancer Asssociation
    • Data Source
      KAKENHI-PROJECT-20K08561
  • [Presentation] Oncolytic activity of sindbis virus for oral cancer cells2008

    • Author(s)
      Saito k., Shirasawa H., Shiiba M., Uzawa K., Tanzawa H
    • Organizer
      3th World Congress on Advances in Oncology and 11th International Symposium on Molecular Medicine
    • Place of Presentation
      Greece Krete
    • Data Source
      KAKENHI-PROJECT-19390508
  • 1.  UZAWA Katsuhiro (30302558)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 2.  TANZAWA HIDEKI (50236775)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  KASAMATSU ATSUSHI (60375730)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  BUKAWA Hiroki (80173558)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  SHIRASAWA Hiroshi (00216194)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 6.  SAITO Kengo (70451755)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 7.  SAKAMOTO Yousuke (50451745)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  OGAWARA KATSUNORI (20372360)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  Nakashima Dai (50431747)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  小池 一幸 (10618060)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  YOKOE Hidetaka (70261930)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SEKI Naohiko (50345013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAKIGUCHI Masaki (40179578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  大越 基弘 (80022888)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  森 良之 (70251296)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  神津 由直 (70400942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  小池 博文 (10595995)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  皆川 康之 (30639787)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  瀧口 裕一 (30272321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  太和田 暁之 (10596159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  新井 誠人 (30396684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  伏見 一章 (90375733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TAKIGUCHI Yuuichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi