BUKAWA Hiroki 武川寛樹

… Alternative Names

Researcher Number	80173558
Other IDs
Affiliation (Current)	2022: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help	2021: 筑波大学, 医学医療系, 教授 2011 – 2019: 筑波大学, 医学医療系, 教授 2009 – 2010: 筑波大学, 医学部, 教授 2009: 筑波大学, 医学部・臨床医学系, 教授 2008: 千葉大学, 医学部・附属病院, 講師 … More
Review Section/Research Field	Principal Investigator Surgical dentistry / 病態科学系歯学(含放射線系歯学) / Surgical dentistry Except Principal Investigator Surgical dentistry / Basic Section 56010:Neurosurgery-related / Anesthesiology/Resuscitation studies / Applied pharmacology / Surgical dentistry / Morphological basic dentistry / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 口腔がん / OK-432 / microRNA / 腫瘍ワクチン / 重合 / Sq-1979 / 血液 / 唾液 / 臨床腫瘍学 / KLN-205 … More Except Principal Investigator 口腔癌 / マイクロアレイ解析 / マイクロアレイ / 神経再生 / VEGF / 遺伝子治療 / 臨床腫瘍学 / 低病原性ウイルス / ウイルスカプシド / 腫瘍特異的吸着 / リポソーム / 腫瘍特異性 / リボソーム / drug delivery system / シンドビスウイルス / microRNA / 癌関連遺伝子 / micro RNA / 癌関連遣伝子 / 口腔扁平上皮癌 / Pax Family / リアルタイムPCR法 / 免疫染色法 / Pax family / プロテオーム解析 / マイクロRNA / 肺高血圧症 / マイクロＲＮＡ / 低酸素 / 腫瘍マーカー / サイトケラチン19フラグメント / 扁平上皮癌 / 半減期 / シフラ / tumor marker / cytokeratin 19 fragment / oral cancer / squamous cell carcinoma / half-life / Ca結合タンパク遺伝子 / 遺伝子発現解析 / 発癌予測 / Ca結合タンパク / ATP2A遺伝子群 / ATP2B遺伝子群 / S100遺伝子群 / oral carcinoma / Ca^<2+> binding protein / microarray / gene expression profile / predictive carcinogenesis / 軸索様神経束の作製 / 歯肉上皮下層由来神経幹細胞 / 脊髄再生治療 / 神経幹細胞 / 脊髄再生 / 脳梗塞 / 歯髄 / 脳神経 / 歯髄幹細胞 / 中枢神経原基 / 神経導管 Less

歯髄幹細胞由来の中枢神経原基を用いた機能的脳脊髄神経の再生医療法の創出
- Principal Investigator
  
  丸島愛樹
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  University of Tsukuba
新規培養法を用いたヒト歯髄・歯肉初代培養由来神経細胞による脳梗塞急性期治療の開発
- Principal Investigator
  
  松丸祐司
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
歯肉上皮下層由来神経幹細胞由来の軸索様神経束の移植による脊髄再生促進
- Principal Investigator
  
  安部哲哉
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Effect of dental pulp stem cell on peripheral nerve regeneration: An experimental study in the nude rat model.Principal Investigator
- Principal Investigator
  
  Bukawa Hiroki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Tsukuba
Functional characterization of oral cancer related microRNA and identification of novel therapeuticsPrincipal Investigator
- Principal Investigator
  
  Bukawa Hiroki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Tsukuba
Altered expression of miRNA and gene expression in lungs of pulmonary arterial hypertension
- Principal Investigator
  
  SAKAI SATOSHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Tsukuba
Functional analysis and clinical application of let-7 microRNA in oral cancerPrincipal Investigator
- Principal Investigator
  
  BUKAWA HIROKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Tsukuba
Development of new bio-therapy with chimeric peptide target tumor cell surface molecules of oral cancerPrincipal Investigator
- Principal Investigator
  
  BUKAWA HIROKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Tsukuba
Diagnosis by microRNA in blood and saliva, and development of the new treatment method to oral cancerPrincipal Investigator
- Principal Investigator
  
  BUKAWA Hiroki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Tsukuba
Functional analysis of microRNA in oral carcinoma.
- Principal Investigator
  
  SHIIBA Masashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Total analysis of Pax family genes in oral carcinoma.
- Principal Investigator
  
  OGAWARA Katsunori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Development of cancer-targeted liposome with viral proteins
- Principal Investigator
  
  UZAWA Katsuhiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Molecular biologic and histopathologic study on the expression status of Ca^<2+> binding protein genes in oral carcinoma
- Principal Investigator
  
  OGAWARA Katsunori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Chiba University
Study on the role of DNA methyltransferases in regulation of the expression of genes associated with the control of cell cyclePrincipal Investigator
- Principal Investigator
  
  BUKAWA Hiroki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Basic research of the OK-432-conjugated tumor vaccinePrincipal Investigator
- Principal Investigator
  
  BUKAWA Hiroki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Yokohama City University
Prediction of relapse of oral cancer by measurement of serum cytokeratin 19 fragment
- Principal Investigator
  
  FUJITA Kiyohide
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Yokohama City University
腫瘍ワクチンによる悪性腫瘍特異的免疫の誘導Principal Investigator
- Principal Investigator
  
  武川寛樹
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Yokohama City University
VEGF発現による虚血性心疾患の遺伝子治療
- Principal Investigator
  
  熊坂秀和
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yokohama City University

All 2018 2017 2016 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] MicroRNA-205-5p suppresses the invasiveness of oral squamous cell carcinoma by inhibiting TIMP?2 expression2018
- Author(s)
  Nagai H, Hasegawa S, Uchida F, Terabe T, Ishibashi Kanno N, Kato K, Yamagata K, Sakai S, Kawashiri S, Sato H, Yanagawa T, Bukawa H.
- Journal Title
  
  Int J Oncol
  
  Volume: 52 Pages: 841-850
- DOI
  10.3892/ijo.2018.4260
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05038, KAKENHI-PROJECT-15H05042, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-26463038
[Journal Article] MicroRNA-155-5p is associated with oral squamous cell carcinoma metastasis and poor prognosis2016
- Author(s)
  Osamu Baba,Shogo Hasegawa,Hiroki Nagai,Fumihiko Uchida,Masanobu Yamatoji,Naomi I. Kanno,Kenji Yamagata,Satoshi Sakai,Toru Yanagawa,Hiroki Bukawa
- Journal Title
  
  J Oral Pathol Med
  
  Volume: 45 Pages: 248-255
- DOI
  10.1111/jop.12351
- NAID
  120007135548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05038, KAKENHI-PROJECT-25293125, KAKENHI-PROJECT-15K15318, KAKENHI-PROJECT-16H05220
[Journal Article] Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer.2006
- Author(s)
  Saito K, Uzawa K, Endo Y, Kato Y, Nakashima D, Ogawara K, Shiba M, Bukawa H, Yokoe H, Tanzawa H.
- Journal Title
  
  Oncol Rep. 15
  
  Pages: 49-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591820
[Journal Article] Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer.2006
- Author(s)
  Saito K, Uzawa K, Endo Y, Kato Y, Nakashima D, Ogawara K, Shiba M, Bukawa H, Yokoe H, Tanzawa H
- Journal Title
  
  Oncol Rep. 15
  
  Pages: 49-55
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591820
[Journal Article] Chromosome 1 open reading frame 10(Clorf10) gene is frequently down-regulated and inhibits cell proliferation in oral squamous cell carcinoma2005
- Author(s)
  Imai FL, Uzawa K, Nimura Y, Moriya T, Imai MA, Shiiba M, Bukawa H, Yokoe H, Tanzawa H.
- Journal Title
  
  Int J Biochem Cell Biol. 37
  
  Pages: 1641-1655
- Data Source
  KAKENHI-PROJECT-16591820
[Journal Article] Chromosome 1 open reading frame 10 (C1orf10) gene is frequently down-regulated and inhibits cell proliferation in oral squamous cell carcinoma2005
- Author(s)
  Imai FL, Uzawa K, Nimura Y, Moriya T, Imai MA, Shiiba M, Bukawa H, Yokoe H, Tanzawa H.
- Journal Title
  
  Int J Biochem Cell Biol. 37
  
  Pages: 1641-1655
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591820
[Journal Article] Chromosome 1 open reading frame 10(Clorf10) gene is frquently down-regulated and inhubits cell proliferation in oral squamous cell carcimoma2005
- Author(s)
  Imai FL, Uzawa K, Nimura Y, Moriya T, Imai MA, Shiiba M, Bukawa H, Yokoe H, Tanzawa H
- Journal Title
  
  Int J Biochem Cell Biol. 37
  
  Pages: 1641-55
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591820
[Journal Article] Sarcoendoplasmic reticulum Ca2+ ATPase type 2 downregulated in human oral squamous cell carcinoma2004
- Author(s)
  Endo Y, Uzawa K, Mochida Y, Shiiba M, Bukawa H, Yokoe H, Tanzawa H
- Journal Title
  
  Int J Cancer 110
  
  Pages: 225-231
- Data Source
  KAKENHI-PROJECT-16591820
[Presentation] 口腔がん組織におけるmicroRNA発現の網羅的解析の意義2017
- Author(s)
  飯泉誠一郎、内田文彦、長井宏樹、寺邊健人、高岡昇平、武内保敏、石橋直美、山縣憲司、柳川　徹、武川寛樹
- Organizer
  第62回（公社）日本口腔外科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15H05038
[Presentation] 口腔がんにおけるmiRNA let-7 family 発現の意義
- Author(s)
  長井宏樹 , 長谷川正午, 馬場脩 , 内田文彦 , 寺邊健人 , 菅野直美 , 大和地正信 , 山縣憲司 , 柳川徹 , 武川寛樹
- Organizer
  第33回日本口腔腫瘍学会総会・学術大会
- Place of Presentation
  奈良
- Year and Date
  2015-01-29 – 2015-01-30
- Data Source
  KAKENHI-PROJECT-25670844
[Presentation] miR-205-5p Targets Interferon Regulatory Factor 1 and Suppresses Metastasis in Oral Cancer Cells
- Author(s)
  Shogo Hasegawa, Fumihiko Uchida, Osamu Baba, Takaaki Ito, Masanobu Yamatoji, Naomi I. Kanno, Kenji Yamagata, Toru Yanagawa, Hiroki Bukawa
- Organizer
  2014 AAOMS Annual Meeting - American Association of Oral and Maxillofacial Surgeons
- Place of Presentation
  ホノルル(USA)
- Year and Date
  2014-09-08 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25670844
[Presentation] 血清・唾液をサンプルとした口腔がん関連遊離microRNAの網羅的発現解析
- Author(s)
  内田文彦、大和地正信、瀬戸佳穂里、馬場　脩、伊藤寛之、山縣憲司、柳川　徹、武川寛樹
- Organizer
  第67回　日本口腔科学会学術会
- Place of Presentation
  栃木県総合分化センター（栃木県）
- Data Source
  KAKENHI-PROJECT-25670844
[Presentation] 口腔癌の頸部リンパ節転移におけるmiR-155-5p とzinc finger protein 703 の関係
- Author(s)
  内田文彦, 長谷川正午, 馬場　脩, 寺邊健人, 伊藤孝明, 大和地正信, 菅野直美, 山縣憲司, 柳川　徹, 武川寛樹
- Organizer
  第59回公益社団法人日本口腔外科学会総会・学術大会
- Place of Presentation
  千葉
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25670844
[Presentation] 口腔がんにおけるmiR-203 の機能解析と臨床応用
- Author(s)
  馬場　脩, 伊藤孝明, 内田文彦, 大和地正信, 菅野直美, 山縣憲司, 長谷川正午, 柳川　徹, 鬼澤浩司郎, 武川寛樹
- Organizer
  第59回公益社団法人日本口腔外科学会総会・学術大会
- Place of Presentation
  千葉
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25670844
[Presentation] miRNA-155-5p Targets ZNF703 and Suppresses Metastasis in Oral Cancer Cells
- Author(s)
  Fumihiko Uchida, Shogo Hasegawa, Osamu Baba, Takaaki Ito, Masanobu Yamatoji, Naomi I. Kanno, Kenji Yamagata, Toru Yanagawa, Hiroki Bukawa
- Organizer
  2014 AAOMS Annual Meeting - American Association of Oral and Maxillofacial Surgeons
- Place of Presentation
  ホノルル(USA)
- Year and Date
  2014-09-08 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25670844
[Presentation] 口腔癌の頸部リンパ節転移におけるmiR-205 とInterferon Regulatory Factor 1 の関係
- Author(s)
  長谷川正午, 内田文彦, 馬場　脩, 長井宏樹, 伊藤孝明, 大和地正信, 菅野直美, 山縣憲司, 柳川　徹, 武川寛樹
- Organizer
  第59回公益社団法人日本口腔外科学会総会・学術大会
- Place of Presentation
  千葉
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25670844
[Presentation] Utility of Saliva in the Evaluation of Microrna Functions as a Tumor Suppressor in Oral Squamous Cell Carcinoma
- Author(s)
  Osamu Baba, Takaaki Ito, Fumihiko Uchida, Masanobu Yamatoji, Naomi I. Kanno, Kenji Yamagata, Shogo Hasegawa, Toru Yanagawa, Hiroki Bukawa
- Organizer
  2014 AAOMS Annual Meeting - American Association of Oral and Maxillofacial Surgeons
- Place of Presentation
  ホノルル(USA)
- Year and Date
  2014-09-08 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25670844

1. UZAWA Katsuhiro (30302558)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. 石川博 (30089784)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SHIIBA Masashi (20301096)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OGAWARA Katsunori (20372360)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. SHODA Junichi (90241827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TANZAWA Hideki (50236775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. 丸島愛樹 (40722525)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SHIRASAWA Hiroshi (00216194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAITO Kengo (70451755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YOKOE Hidetaka (70261930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAWAKAMI Koji (70422318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAKAI SATOSHI (30282362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. SUMIDA Takayuki (00183054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYAUCHI Takashi (60222329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. WARABI Eiji (70396612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUJITA Kiyohide (90106328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. CHIKUMARU Hiroshi (80217231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ONO Kanae (60344983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 熊坂秀和 (80234516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 野一色泰晴 (60033263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 工藤一大 (30145700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 奥村福一郎 (50028487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 柳川徹 (10312852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. 安部哲哉 (00708430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 國府田正雄 (50361449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 松丸祐司 (70323300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 豊村順子 (80645630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 大山晃弘 (90538232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 川尻秀一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 内田隆史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
31. 加藤広禄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

BUKAWA Hiroki 武川 寛樹

武川 寛樹 ブカワ ヒロキ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of dental pulp stem cell on peripheral nerve regeneration: An experimental study in the nude rat model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional characterization of oral cancer related microRNA and identification of novel therapeuticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis and clinical application of let-7 microRNA in oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new bio-therapy with chimeric peptide target tumor cell surface molecules of oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Diagnosis by microRNA in blood and saliva, and development of the new treatment method to oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the role of DNA methyltransferases in regulation of the expression of genes associated with the control of cell cyclePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

BUKAWA Hiroki 武川寛樹

武川寛樹ブカワヒロキ