YAMAKUCHI Munekazu 山口宗一

… Alternative Names

山口宗一ヤマクチムネカズ

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Researcher Number	20325814
Other IDs
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 鹿児島大学, 医歯学域医学系, 准教授 2017: 鹿児島大学, 医歯(薬)学総合研究科, 准教授 2017: 鹿児島大学, 医歯(薬)学総合研究科, 助手 2014: 鹿児島大学, 大学院医歯学総合研究科, 准教授 2013 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 准教授 2005: 鹿児島大学, 大学院医歯学総合研究科, 助手 2001 – 2002: 鹿児島大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 52010:General internal medicine-related / Medium-sized Section 52:General internal medicine and related fields / Orthopaedic surgery Except Principal Investigator Basic Section 52010:General internal medicine-related / Basic Section 55030:Cardiovascular surgery-related / Emergency medicine / Laboratory medicine / Basic Section 53020:Cardiology-related / Basic Section 53050:Dermatology-related … More / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Ophthalmology / General internal medicine(including psychosomatic medicine) / Dermatology / Neurology / Anesthesiology/Resuscitation studies / Hematology / Laboratory medicine / Circulatory organs internal medicine Less
Keywords	Principal Investigator 血管内皮細胞 / miRNA / microRNA / エクソゾーム / 動脈硬化 / 単球 / 一酸化窒素 / 糖尿病 / 血小板 / マイクロRNA … More / exosome / ASO / 血管内皮機能 / 血管 / p53 / 単核球 / TP53 / two-hybrid / BMP-2 / L6細胞 / 14-3-3 / Yeast two hybrid / 筋肉分化 / MEF2C … More Except Principal Investigator VEGF / HMGB1 / 血小板 / マイクロRNA / VEGF-A / アポトーシス / miRNA / microRNA / エクソソーム / platelet / DIC / DAMPs / PAMPs / 血管新生 / eryptosis / 赤血球 / HMG-1 / ずり応力 / 大動脈弁狭窄症 / 血小板機能異常症 / CalDAG-GEFI / 人工心肺 / Thrombomodulin / 五苓散 / 漢方薬 / 腎炎 / 乾癬 / 好中球 / erythrocyte / Crow-Fukase syndrome / diabetic retinopathy / atherosclerosis / megakaryocyte / transgenic mouse / POEMS syndrome / トロンボモジュリン / protein C / RAMPs / Histones / 老化 / 鉄 / B細胞 / 免疫 / 血球貪食 / リンパ節 / 脾臓 / 多臓器不全 / 敗血症性ショック / HMGB-1 / 血管内皮細胞 / フォンウィルブランド因子 / Large multimer index / von Willebrand factor / 心房細動 / 唾液 / 血小板内シグナリング / 血栓止血 / MYLK / MLCK / 血管平滑筋細胞石灰化 / 心血管疾患 / 石灰化 / 血管平滑筋 / 食後高血糖 / 血管内皮細胞機能障害 / シアストレス / ステントグラフト内挿術 / 大動脈瘤 / 低密度好中球 / 好中球性皮膚症 / ケラチノサイト / マイクロＲＮＡ / 凝固カスケード / 臨床検査 / トロンビン阻害薬濃度 / 活性化凝固第Ⅹ因子阻害薬 / 偽陽性 / トロンビン阻害薬血中濃度測定 / 活性化凝固第Ⅹ因子阻害薬血中濃度測定 / 凝固波形解析 / 凝固因子活性 / クロスミキシングテスト / DOACs血中濃度 / トロンビン阻害薬 / 活性化凝固第X因子阻害薬 / 血管内皮増殖因子 / klotho / 酸化 / 炎症 / RASGRP2 / カルシウム / 血小板シグナリング / Rap1 / RasGRP2 / バイオマーカー / 心室中隔欠損症 / 血管増殖因子 / 腎機能障害 / 肺高血圧症 / 小児心臓手術 / NASH / ＶＥＧＦ / ＮＡＳＨ / 2型糖尿病 / 肝細胞癌 / shock / skimming / sludging / exosome / Thrombomodulin(TM) / Blood sludging / Blood skimming / 組織因子 / 第Ⅶ因子 / 血栓塞栓症 / 癌 / blood sludging / blood skimming / Trousseau syndrome / Thrombosis / Cancer Procoagulant / Exosome / 血球成分 / 血漿成分 / 出血 / 血栓・塞栓 / T-TAS / Sludging / Skimming / 血流動態異常 / choroid / vitrectomy / image analysis / vitreous body / ヒアロサイト / 網膜剥離 / 網膜色素上皮細胞 / 光干渉断層計 / 網膜疾患 / 硝子体細胞 / 画像診断 / 脈絡膜 / 網膜色素上皮 / 画像 / 機械学習 / 画像処理 / サイトカイン / 硝子体 / thrombin / EPCR / Protein C / TM / Thrombin / 修復 / 止血 / 組織損傷 / プロテインC / 生体損傷 / RAMPｓ / PAMPｓ / DAMPｓ / 炎症制御 / 顆粒球吸着除去療法 / NETosis / ネクローシス / プログラム細胞死 / 白血球 / 血栓 / 生理学 / 生体分子 / シグナル伝達 / 細胞・組織 / トランスレーショナルリサーチ / inflammation / thrombosis / programmed cell death / molecular clock / program cell death / apoptosis / 肝癌 / セロトニン / prognosis / exhaust platelet / hepatocellular carcinoma / serotonin / メラノーマ細胞株A375 / Alix / Heat shock protein / 糖鎖構造 / iron metabolism / phagocytosis / lymph node / programmed cell deat / 免疫寛容 / リンパ管新生 / 血栓症 / 動脈硬化 / 内皮細胞 / Crow-Rukase syndrome / VFGF / polymyxin B / septic shock / 2-arachidonylflyceorol / endocannabinoids / anandamide / ポリミキシンB / エンドトキシンショック / アナンダマイド / 妊娠中毒症 / 敗血症 / ショックのメディエーター / 内因性カンナビノイド / 感染症性ショック / エピジェネティック / HMGB1酸化還元型 / ヒト化モノクローナル抗体 / レドックス状態 / ヒストン / NETs / thrombomodulin / histones / Shock / Alarmin / 活性酸素 / 肝 / 脾 / hepcidin / 血管内皮細胞増殖因子 / 病態検査学 / 貧血 / 鉄代謝 / 血管透過性 / 病理学 / 微生物 / 細菌 / 感染症 / 個体死 / 核内蛋白 / 細胞壊死 / TNFα / ARDS / RAGE / トロンボモヂュリン / EC-SOD / セレノプロテインP Less

CalDAG-GEFIの網膜色素変性症における機能解析と新規機能の探索
- Principal Investigator
  
  古城剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
MicroRNA elucidation of the pathogenesis of vascular smooth muscle cell calcification from postprandial hyperglycemia
- Principal Investigator
  
  藤崎知園子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
止血異常を引き起こしたMLCK分子異常の原因解明に向けた網羅的機能解析
- Principal Investigator
  
  小浜祐行
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
Search for MicroRNAs in Saliva as a Pathway to Early Detection of Atrial Fibrillation
- Principal Investigator
  
  二宮雄一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kagoshima University
VEGFアイソフォームに着目したずり応力による血管異型の機序解明
- Principal Investigator
  
  立岡修治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kagoshima University
低密度好中球(LDN)のmiRNAを治療標的とした好中球性皮膚症の病態解明
- Principal Investigator
  
  東裕子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kagoshima University
大動脈瘤ステントグラフト内挿術前後の凝固線溶動態の解析とエンドリークの機序解明
- Principal Investigator
  
  豊川建二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kagoshima University
circRNA-miRNAによる大動脈弁狭窄症病態解明とバイオマーカー創出の挑戦Principal Investigator
- Principal Investigator
  
  山口宗一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
活性化凝固第X因子阻害薬内服患者のトロンビン阻害薬濃度偽陽性となるメカニズム解明
- Principal Investigator
  
  中村政敏
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
The regulatory mechanism of vascular inflammation convergence by temporal and spatial axesPrincipal Investigator
- Principal Investigator
  
  Yamakuchi Munekazu
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kagoshima University
Elucidation of the molecular mechanism of hemostasis and search for novel functions of CalDAG-GEF1
- Principal Investigator
  
  Kojo Tsuyoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
Large metabolic nexus of the concept of renal deficiency as seen from Klotho
- Principal Investigator
  
  Oyama Yoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
Elucidation of molecular mechanism of systemic vascular changes due to aortic stenosis-role of platelet activation by shear stress
- Principal Investigator
  
  Kanda Hideaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kagoshima University
Clarification of the mechanism on hepatocellular carcinoma in diabetes: VEGF-targeted therapy strategy
- Principal Investigator
  
  NAKASHIMA Kazuhisa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
Molecular mechanism of activated white blood cells by cardiopulmonary bypass for human body in pediatric cardiac surgery.
- Principal Investigator
  
  Imoto Yutaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kagoshima University
The role of p53 in atherosclerosisPrincipal Investigator
- Principal Investigator
  
  Yamakuchi Munekazu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kagoshima University
Cellular and molecular mechanism of blood sludging/skimming. Causative role of cancer exosomes and their pathophysiological view points
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kagoshima University
Construction of A New Paradigm for Diagnosis and Treatment of Atherosclerosis ObliteransPrincipal Investigator
- Principal Investigator
  
  Yamakuchi Munekazu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagoshima University
Can Kampo Medicines treat chronic kidney disease? : Challenge to elucidate the inflammation control mechanism of traditional herbal medicine
- Principal Investigator
  
  OYAMA Yoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Kagoshima University
Novel therapeutic proposal for DIC/Shock: from Damage-Sensing/-Control to Damage Resolution
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Kagoshima University
Analysis for pro grammed cell death of anuclear platelets and erythrocytes for application of laboratory medicine
- Principal Investigator
  
  Hashiguchi Teruto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
Elucidation of pathophysiology of inflammatory skin disease from the viewpoint of neutrophil function and establishment of its treatment
- Principal Investigator
  
  Higashi Yuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kagoshima University
Construction of the system ofPrincipal Investigator
- Principal Investigator
  
  Yamakuchi Munekazu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
Fine tuning the immune response through physiological hemophagocytosis
- Principal Investigator
  
  Hashiguchi Teruto
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
Proposal of novel concept, Exosome cargo as a novel DAMPs delivery system
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Kagoshima University
Study of comprihensive vitreology
- Principal Investigator
  
  SAKAMOTO Taiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University
The role of Endothelial miRNA in the regulation of vascular integrityPrincipal Investigator
- Principal Investigator
  
  Yamakuchi Munekazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
Multi-layered and topological regulatory system of PAMPs and DAMPs. Its relevance in various pathophysiology.
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Kagoshima University
The role of microRNA in diabetes associated vascular dysfunctionPrincipal Investigator
- Principal Investigator
  
  MUNEKAZU Yamakuchi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
Contribution of vascular permeability for aging erythrocyte selection in spleen
- Principal Investigator
  
  HASHIGUCHI Teruto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
凝固外因系と自然免疫系のクロストークとシナージズム
- Principal Investigator
  
  丸山征郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kagoshima University
"死のメディエーター":HMG-1の高感度測定と多臓器不全の診断法の確立
- Principal Investigator
  
  丸山征郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagoshima University
筋萎縮のメカニズム解明:転写因子MEF2familyを介してのシグナルPrincipal Investigator
- Principal Investigator
  
  山口宗一
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
新規レドックス制御因子:セレノプロテインPの機能とその分子病態
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kagoshima University
Molecular and cellular basis of septic shock : Involvement of anandamide and HMG-1
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kagoshima University
Proposal of the new concept, "Platelet VEGF"
- Principal Investigator
  
  HASHIGUCHI Teruto
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Patent

[Book] 細胞　p53分子と血管炎症のかかわり2020
- Author(s)
  山口宗一
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-18K19523
[Book] 細胞　p53分子と血管炎症のかかわり2020
- Author(s)
  山口宗一
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-18H02734
[Book] 臨床病理　miRNAによる自然免疫制御機構2019
- Author(s)
  山口宗一, 郡山豊泰, 清水利昭, 竹之内和則, 大山陽子, 政元いずみ, 橋口照人
- Total Pages
  12
- Publisher
  日本臨床検査医学会
- Data Source
  KAKENHI-PROJECT-18K19523
[Book] Cardio-Coagulation 　バイオマーカーを理解する　von Willebrand 因子2019
- Author(s)
  山口宗一
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18K19523
[Book] 臨床病理　miRNAによる自然免疫制御機構2019
- Author(s)
  山口宗一, 郡山豊泰, 清水利昭, 竹之内和則, 大山陽子, 政元いずみ, 橋口照人
- Total Pages
  12
- Publisher
  日本臨床検査医学会
- Data Source
  KAKENHI-PROJECT-18H02734
[Book] 血栓止血血管学2015
- Author(s)
  山口宗一
- Total Pages
  250
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-26293130
[Book] 血管病のmicroRNA2015
- Author(s)
  山口宗一
- Total Pages
  50
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-15K15196
[Book] 血栓止血血管学2015
- Author(s)
  一瀬白帝、丸山征郎、内山真一郎、山口宗一
- Total Pages
  250
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-15K15196
[Book] 血管病のmicroRNA2015
- Author(s)
  山口宗一
- Total Pages
  50
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-26293130
[Book] 広がる血管microRNAの役割2014
- Author(s)
  山口宗一、橋口照人
- Total Pages
  8
- Publisher
  臨床化学
- Data Source
  KAKENHI-PROJECT-26293130
[Book] Post-marketing surveillance of thrombomodulin alfa, a novel treatment of disseminated intravascular coagulation ;Safety and efficacy in 1.032 patients with hematologic malignancy.2014
- Author(s)
  Teruto Hashiguchi and Munekazu yamakuchi
- Total Pages
  4
- Publisher
  International Review of Thrombosis
- Data Source
  KAKENHI-PROJECT-26293130
[Book] 臨床化学2014
- Author(s)
  山口宗一
- Total Pages
  9
- Publisher
  日本臨床化学会
- Data Source
  KAKENHI-PROJECT-25893192
[Book] Iron Regulatory Protein 1 / HIF2α軸―鉄代謝調節メカニズムの新展開―臨床化学会2014
- Author(s)
  橋口照人、Binita Shrestha、伊藤隆史、山口宗一
- Data Source
  KAKENHI-PROJECT-25893192
[Book] デオキシチミジンキナーゼ臨床検査ガイド2013～20142013
- Author(s)
  山口宗一
- Total Pages
  1128
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25893192
[Journal Article] Anti-ganglionic acetylcholine receptor antibodies in functional neurological symptom disorder/conversion disorder2023
- Author(s)
  Nagata Ryusei、Matsuura Eiji、Nozuma Satoshi、Dozono Mika、Noguchi Yutaka、Ando Masahiro、Hiramatsu Yu、Kodama Daisuke、Tanaka Masakazu、Kubota Ryuji、Yamakuchi Munekazu、Higuchi Yujiro、Sakiyama Yusuke、Arata Hitoshi、Higashi Keiko、Hashiguchi Teruto、Nakane Shunya、Takashima Hiroshi
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 14 Pages: 01-07
- DOI
  10.3389/fneur.2023.1137958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19454, KAKENHI-PROJECT-23K24234, KAKENHI-PROJECT-23K24380
[Journal Article] Neutrophil-Derived MicroRNA-1290 Promotes Keratinocyte Proliferation in Psoriasis2023
- Author(s)
  Higashi Yuko、Yamakuchi Munekazu、Ibusuki Atsuko、Okubo Aoi、Fukushige Tomoko、Hashiguchi Teruto、Kanekura Takuro
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: - Issue: 7 Pages: 03209-8
- DOI
  10.1016/j.jid.2023.10.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08385, KAKENHI-PROJECT-21K08329, KAKENHI-PROJECT-23K24234
[Journal Article] VEGF-A165 is the predominant VEGF-A isoform in platelets, while VEGF-A121 is abundant in serum and plasma from healthy individuals2023
- Author(s)
  Yamakuchi Munekazu、Okawa Masashi、Takenouchi Kazunori、Bibek Aryal、Yamada Shingo、Inoue Keiichi、Higurashi Kazuhiko、Tabaru Akito、Tanoue Kiyonori、Oyama Yoko、Higashi Sadayuki、Fujisaki Chieko、Kanda Hideaki、Terasaki Hiroto、Sakamoto Taiji、Soga Yoshiharu、Hashiguchi Teruto
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 4 Pages: 1-15
- DOI
  10.1371/journal.pone.0284131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19454, KAKENHI-PROJECT-22K07388, KAKENHI-PROJECT-21K11626, KAKENHI-PROJECT-21H03095, KAKENHI-PROJECT-23K24234
[Journal Article] Total atrial conduction time as a possible predictor of atrial fibrillation recurrence after catheter ablation for paroxysmal atrial fibrillation: relationship between electrical atrial remodeling and structural atrial remodeling time courses2021
- Author(s)
  Maenosono Ryuichi、Mizukami Naoko、Ichiki Hitoshi、Oketani Naoya、Namino Fuminori、Masamoto Izumi、Yuasa Toshinori、Yamakuchi Munekazu、Ohishi Mitsuru、Hashiguchi Teruto
- Journal Title
  
  Journal of Medical Ultrasonics
  
  Volume: 48 Issue: 3 Pages: 295-306
- DOI
  10.1007/s10396-021-01090-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17608, KAKENHI-PROJECT-19K07918, KAKENHI-PROJECT-21K19454
[Journal Article] 1,5-Anhydro-D-fructose Protects against Rotenone-Induced Neuronal Damage In Vitro through Mitochondrial Biogenesis2021
- Author(s)
  Kasamo Yuki、Kikuchi Kiyoshi、Yamakuchi Munekazu、Otsuka Shotaro、Takada Seiya、Kambe Yuki、Ito Takashi、Kawahara Ko-ichi、Arita Kazunori、Yoshimoto Koji、Maruyama Ikuro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 18 Pages: 9941-9941
- DOI
  10.3390/ijms22189941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19312, KAKENHI-PROJECT-21H03037, KAKENHI-PROJECT-20K11640, KAKENHI-PROJECT-21K19454, KAKENHI-PROJECT-21K19544
[Journal Article] Dynamic changes in platelets caused by shear stress in aortic valve stenosis2021
- Author(s)
  Hideaki Kanda, Munekazu Yamakuchi, Kazuhisa Matsumoto, Kosuke Mukaihara, Yoshiya Shigehisa, Shuji Tachioka, Masashi Okawa, Kazunori Takenouchi, Yoko Oyama, Teruto Hashiguchi, and Yutaka Imotoa
- Journal Title
  
  Clinical Hemorheology and Microcirculation
  
  Volume: 77 Issue: 1 Pages: 71-81
- DOI
  10.3233/ch-200928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09130, KAKENHI-PROJECT-18H02734
[Journal Article] Evaluation of VEGF-A in platelet and microRNA-126 in serum after coronary artery bypass grafting2021
- Author(s)
  Mukaihara Kosuke、Yamakuchi Munekazu、Kanda Hideaki、Shigehisa Yoshiya、Arata Kenichi、Matsumoto Kazuhisa、Takenouchi Kazunori、Oyama Yoko、Koriyama Toyoyasu、Hashiguchi Teruto、Imoto Yutaka
- Journal Title
  
  Heart and Vessels
  
  Volume: 36 Issue: 11 Pages: 1635-1645
- DOI
  10.1007/s00380-021-01855-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19454, KAKENHI-PROJECT-20K16527
[Journal Article] Bivalent property of intra-platelet VWF in liver regeneration and HCC recurrence: A prospective multicenter study2019
- Author(s)
  Aryal Bibek、Yamakuchi Munekazu、Shimizu Toshiaki、Kadono Jun、Furoi Akira、Gejima Kentaro、Takenouchi Kazunori、Komokata Teruo、Hashiguchi Teruto、Imoto Yutaka
- Journal Title
  
  Cancer Biomarkers
  
  Volume: 26 Issue: 1 Pages: 51-61
- DOI
  10.3233/cbm-190168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02734, KAKENHI-PROJECT-18K19523
[Journal Article] Dynamics of Soluble Thrombomodulin and Circulating miRNAs in Patients with Atrial Fibrillation Undergoing Radiofrequency Catheter Ablation2019
- Author(s)
  Namino F, Yamakuchi M, Iriki Y, Okui H, Ichiki H, Maenosono R, Oketani N, Masamoto I, Miyata M, Horiuchi M, Hashiguchi T, Ohishi M, Maruyama I
- Journal Title
  
  Clin Appl Thromb Hemost
  
  Volume: 25 Pages: 107602961985157-107602961985157
- DOI
  10.1177/1076029619851570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09593, KAKENHI-PROJECT-19K17608, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
[Journal Article] Application of high-mannose-type glycan-specific lectin from Oscillatoria Agardhii for affinity isolation of tumor-derived extracellular vesicles2019
- Author(s)
  Yamamoto Mika、Harada Yoichiro、Suzuki Takehiro、Fukushige Tomoko、Yamakuchi Munekazu、Kanekura Takuro、Dohmae Naoshi、Hori Kanji、Maruyama Ikuro
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 580 Pages: 21-29
- DOI
  10.1016/j.ab.2019.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08272, KAKENHI-PROJECT-17H03926, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18H02734, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19523, KAKENHI-PROJECT-18K19587
[Journal Article] Predictive Value of Diminished Serum PDGF-BB after Curative Resection of Hepatocellular Cancer2019
- Author(s)
  Aryal Bibek、Yamakuchi Munekazu、Shimizu Toshiaki、Kadono Jun、Furoi Akira、Gejima Kentaro、Komokata Teruo、Koriyama Chihaya、Hashiguchi Teruto、Imoto Yutaka
- Journal Title
  
  Journal of Oncology
  
  Volume: 2019 Pages: 1-8
- DOI
  10.1155/2019/1925315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19523, KAKENHI-PROJECT-16H05229, KAKENHI-PROJECT-18H02734
[Journal Article] Intra-platelet Serotonin as a Biomarker in HCC Recurrence: When Time Matters2019
- Author(s)
  Aryal Bibek、Yamakuchi Munekazu、Hashiguchi Teruto、Imoto Yutaka
- Journal Title
  
  Journal of Cancer
  
  Volume: 10 Issue: 11 Pages: 2384-2385
- DOI
  10.7150/jca.30696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02734, KAKENHI-PROJECT-18K19523
[Journal Article] Legionella pneumophila infection-mediated regulation of RICTOR via miR-218 in U937 macrophage cells2019
- Author(s)
  Koriyama Toyoyasu、Yamakuchi Munekazu、Takenouchi Kazunori、Oyama Yoko、Takenaka Hiroyoshi、Nagakura Takumi、Masamoto Izumi、Hashiguchi Teruto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Issue: 2 Pages: 608-613
- DOI
  10.1016/j.bbrc.2018.11.093
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19523, KAKENHI-PROJECT-18H02734, KAKENHI-PROJECT-18K15395
[Journal Article] Therapeutic implication of platelets in liver regeneration ?hopes and hues2018
- Author(s)
  Aryal Bibek、Yamakuchi Munekazu、Shimizu Toshiaki、Kadono Jun、Furoi Akira、Gejima Kentaro、Komokata Teruo、Hashiguchi Teruto、Imoto Yutaka
- Journal Title
  
  Expert Review of Gastroenterology & Hepatology
  
  Volume: 12 Issue: 12 Pages: 1219-1228
- DOI
  10.1080/17474124.2018.1533813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19523, KAKENHI-PROJECT-16H05229, KAKENHI-PROJECT-18H02734
[Journal Article] Deciphering Platelet Kinetics in Diagnostic and Prognostic Evaluation of Hepatocellular Carcinoma2018
- Author(s)
  Aryal Bibek、Yamakuchi Munekazu、Shimizu Toshiaki、Kadono Jun、Furoi Akira、Gejima Kentaro、Komokata Teruo、Hashiguchi Teruto、Imoto Yutaka
- Journal Title
  
  Canadian Journal of Gastroenterology and Hepatology
  
  Volume: 2018 Pages: 1-9
- DOI
  10.1155/2018/9142672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19523, KAKENHI-PROJECT-16H05229, KAKENHI-PROJECT-18H02734, KAKENHI-PROJECT-18F16420, KAKENHI-PROJECT-16K10130
[Journal Article] IL-13 enhances mesenchymal transition of pulmonary artery endothelial cells via down-regulation of miR-424/503 in vitro.2018
- Author(s)
  Takagi K, Yamakuchi M, Matsuyama T, Kondo K, Uchida A, Misono S, Hashiguchi T, Inoue H.
- Journal Title
  
  Cell Signal.
  
  Volume: 42 Pages: 270-280
- DOI
  10.1016/j.cellsig.2017.10.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10130
[Journal Article] Endothelial Cell Aging: How miRNAs Contribute?2018
- Author(s)
  Yamakuchi Munekazu、Hashiguchi Teruto
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 7 Issue: 7 Pages: 170-170
- DOI
  10.3390/jcm7070170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19523, KAKENHI-PROJECT-18H02734, KAKENHI-PROJECT-16K10130
[Journal Article] Deciphering Platelet Kinetics in Diagnostic and Prognostic of Hepatocellular Carcinoma2018
- Author(s)
  Bibek Aryal, Munekazu Yamakuchi, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Teruo Komokata, Kentaro Gejima, Teruto Hashiguchi, Yutaka Imoto
- Journal Title
  
  Canadian Journal of Gastroenterology and Hepatology
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05229
[Journal Article] High-fat diet exacerbates imiquimod-induced psoriasis-like dermatitis in mice.2018
- Author(s)
  Higashi Y, Yamakuchi M, Fukushige T, Ibusuki A, Hashiguchi T, Kanekura T.
- Journal Title
  
  Exp Dermatol.
  
  Volume: 27 Issue: 2 Pages: 178-184
- DOI
  10.1111/exd.13484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10130, KAKENHI-PROJECT-16K19732
[Journal Article] Low grade inflammation inhibits VEGF induced HUVECs migration in p53 dependent manner.2017
- Author(s)
  Panta S, Yamakuchi M, Shimizu T, Takenouchi K, Oyama Y, Koriyama T, Kojo T, Hashiguchi T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 483 Issue: 2 Pages: 803-809
- DOI
  10.1016/j.bbrc.2016.12.096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05229, KAKENHI-PROJECT-26293130, KAKENHI-PROJECT-15K15196, KAKENHI-PROJECT-15K15197
[Journal Article] Post-Resection Exhaustion of Intra-Platelet Serotonin: Also an Indicator of Early Hepatocellular Carcinoma Recurrence?2017
- Author(s)
  Aryal B, Shimizu T, Kadono J, Furoi A, Komokata T, Kitazono I, Koriyama C, Yamakuchi M, Hashiguchi T, Imoto Y.
- Journal Title
  
  J Cancer
  
  Volume: 8 Issue: 19 Pages: 3984-3991
- DOI
  10.7150/jca.20971
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05229, KAKENHI-PROJECT-16F16420
[Journal Article] PERMEABILITY AND ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR EFFECTS OF BEVACIZUMAB, RANIBIZUMAB, AND AFLIBERCEPT IN POLARIZED RETINAL PIGMENT EPITHELIAL LAYER IN VITRO.2017
- Author(s)
  Yoshihara N, Terasaki H, Shirasawa M, Kawano H, Sonoda S, Yamakuchi M, Hashiguchi T, Hisatomi T, Ishibashi T, Sakamoto T.
- Journal Title
  
  Retina
  
  Volume: 37(1) Issue: 1 Pages: 179-190
- DOI
  10.1097/iae.0000000000001117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293130, KAKENHI-PROJECT-15K15196, KAKENHI-PROJECT-15K20270, KAKENHI-PROJECT-15K10873
[Journal Article] Decreased Expression of Thrombomodulin in Endothelial Cells by Fibroblast Growth Factor-23/α-Klotho.2017
- Author(s)
  Tanaka K, Salunya T, Motomiya Y, Motomiya Y, Oyama Y, Yamakuchi M, Maruyama I.
- Journal Title
  
  Ther Apher Dial
  
  Volume: 21（4） Issue: 4 Pages: 395-404
- DOI
  10.1111/1744-9987.12524
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04363
[Journal Article] A Switch in the Dynamics of Intra-Platelet VEGF-A from Cancer to the Later Phase of Liver Regeneration after Partial Hepatectomy in Humans2016
- Author(s)
  Aryal B, Shimizu T, Kadono J, Furoi A, Komokata T, Inoue M, Ikeda S, Fukukura Y, Nakamura M, Yamakuchi M, Hashiguchi T, Imoto Y
- Journal Title
  
  PLoS One
  
  Volume: 11(3) Issue: 3 Pages: e0150446-e0150446
- DOI
  10.1371/journal.pone.0150446
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15196, KAKENHI-PROJECT-15K15197, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-26293130, KAKENHI-PROJECT-16H05229
[Journal Article] HMGB1 is secreted by 3T3-L1 adipocytes through JNK signaling and the secretion is partially inhibited by adiponectin.2016
- Author(s)
  Shimizu T, Yamakuchi M, Biswas KK, Aryal B, Yamada S, Hashiguchi T, Maruyama I.
- Journal Title
  
  Obesity (Silver Spring).
  
  Volume: 24(9) Issue: 9 Pages: 1913-21
- DOI
  10.1002/oby.21549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293385, KAKENHI-PROJECT-16K15763
[Journal Article] SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor2015
- Author(s)
  Zhu Q, Yamakuchi M, Lowenstein CJ
- Journal Title
  
  PLoS One
  
  Volume: 10(8) Issue: 8 Pages: e0118737-e0118737
- DOI
  10.1371/journal.pone.0118737
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15196, KAKENHI-PROJECT-26293130
[Journal Article] Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.2014
- Author(s)
  Huang J, Huffman JE, Yamakuchi M,... Lowenstein CJ, Strachan DP, O'Donnell CJ; CHARGE Consortium Hemostatic Factor Working Group.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 34(5) Issue: 5 Pages: 1093-1101
- DOI
  10.1161/atvbaha.113.302088
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293130
[Journal Article] Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.2014
- Author(s)
  Zhu Q, Yamakuchi M, Ture S, de la Luz Garcia-Hernandez M, Ko KA, Modjeski KL, LoMonaco MB, Johnson AD, O'Donnell CJ, Takai Y, Morrell CN, Lowenstein CJ.
- Journal Title
  
  J Clin Invest.
  
  Volume: 124 Issue: 10 Pages: 4503-4516
- DOI
  10.1172/jci71245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21227005, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26293130
[Journal Article] Upregulation of non-β Cell-derived Vascular Endothelial Growth FactorA Increases Small Clusters of Insulin producing Cells in the Pancreas.2014
- Author(s)
  Takenouchi K, Shrestha B, Yamakuchi M, Yoshinaga M, Arimura N, Kawaguchi H, Nagasato T, Feil R, Kawahara K-I, Sakamoto T, Maruyama I, Hashiguchi T.
- Journal Title
  
  Experimental and Clinical Endocrinology & Diabetes
  
  Volume: in press Issue: 05 Pages: 308-15
- DOI
  10.1055/s-0034-1371811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659282, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26293130
[Journal Article] Post- marketing surveillance of thrombomodulin alfa, a novel treatment of disseminated intravascular coagulation - Safety and efficacy in 1,032 patients with hematologic malignancy2014
- Author(s)
  Hashiguchi T, Yamakuchi M
- Journal Title
  
  Thrombosis Research
  
  Volume: 133 Pages: 364-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893192
[Journal Article] Upregulation of non-βCell-derived Vascular Endothelial Growth Factor A Increases Small Clusters of Insulin-producing Cells in the Pancreas2014
- Author(s)
  Takenouchi K, Shrestha B, Yamakuchi M, Yoshinaga N, Arimura N, Kawaguchi H, Nagasato T, Feil R, Kawahara K, Sakamoto T, Maruyama I, Hashiguchi T
- Journal Title
  
  Exp C lin Endocrinol Diabetes
  
  Volume: 122(5) Pages: 308-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893192
[Journal Article] CHARGE Consortium Hemostatic Factor Working Group. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX22014
- Author(s)
  Huang J, Huffman JE, Yamakuchi M, Trompet S,Lowenstein CJ, Strachan DP, O'Donnell CJ
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 4(5) Pages: 1093-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893192
[Journal Article] Saturated fatty acid palmitate induces extracellular release of histone H3: a possible mechanistic basis for high-fat diet-induced inflammation and thrombosis2013
- Author(s)
  Shrestha C, Ito T, Kawahara K, Shrestha B, Yamakuchi M, Hashiguchi T, Maruyama I
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 437(4) Pages: 573-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893192
[Journal Article] Saturated fatty acid palmitate induces extracellular release of histone H3 : a Possible mechanistic basis for high-fat diet-induced inflammation and thrombosis.2013
- Author(s)
  Shrestha C, Ito T, et al.
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 437(4) Issue: 4 Pages: 573-578
- DOI
  10.1016/j.bbrc.2013.06.117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02424, KAKENHI-PROJECT-24659282, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-25670764
[Patent] 抗 VEGF-A 抗体による癌に対する治療応答性を予測又は決定するための方法2020
- Inventor(s)
  橋口照人・山口宗一・竹之内和則・大川政士・井本浩以下2名
- Industrial Property Rights Holder
  橋口照人・山口宗一・竹之内和則・大川政士・井本浩以下2名
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] MicroRNA and granulocyte and monocyte adsorption apheresis (GMA) on Neutrophilic skin diseases2023
- Author(s)
  Higashi Y, Yamakuchi M, Fukushige T, Hashiguchi T, Kanekura T.
- Organizer
  First international societies for investigative dermatology meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] 閉塞性動脈硬化症手術前後のABIとmicroRNAについての検討2023
- Author(s)
  立岡修治、重久喜哉、上田英昭、大川政士、山口宗一、里園秀之、樋渡啓生、安村拓人、白桃雄太、藏元慎也、川井田啓介、向原公介、豊川建二、今釜逸美、松本和久、橋口照人、曽我欣治
- Organizer
  第53回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] 冠動脈バイパス手術における血清中miR-223変化の検討2023
- Author(s)
  立岡修治, 向原公介, 上田英昭, 山口宗一, 里園秀之, 樋渡啓生, 白桃雄太, 藏元慎也, 川井田啓介, 豊川建二, 今釜逸美, 松本和久, 橋口照人, 曽我欣治
- Organizer
  第76回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] 左房内Pentraxin3の心房細動アブレーション前後の変化と左房機能関連因子との関連2023
- Author(s)
  鉛山かおり, 波野史典, 市来仁志, 鎌田博之, 吉元一成, 二宮雄一, 堀添善尚, 笠畑拓志, 政元いずみ, 山口宗一, 橋口照人, 大石充
- Organizer
  第87回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19454
[Presentation] VEGF-A121とVEGF-A165の血漿、血清、血小板中の定量比較解析2023
- Author(s)
  藤崎知園子, 山口宗一, 大川政士, 竹之内和則, 東貞行, 田上聖徳, 田原明人, 大山陽子, 橋口照人
- Organizer
  第70回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] MicroRNA and granulocyte and monocyte adsorption apheresis (GMA) on Neutrophilic skin diseases2023
- Author(s)
  Yuko Higashi, Munekazu Yamakuchi, Tomoko Fukushige, Teruto Hashiguchi, Takuro Kanekura
- Organizer
  First international societies for investigative dermatology meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08385
[Presentation] 血漿、血清中と血小板内のVEGF-A121 とVEGF-A165の検討　－VEGF-Aアイソフォーム特異的ELISAの構築－2023
- Author(s)
  山口宗一、大川政士、竹之内和則、東貞行、藤崎知園子、大山陽子、田上聖徳、田原明人、橋口照人
- Organizer
  日本医療検査科学会第55回大会
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] 閉塞性動脈硬化症手術前後のABIとmicroRNAについての検討2023
- Author(s)
  立岡修治、重久喜哉、上田英昭、大川政士、山口宗一、里園秀之、樋渡啓生、安村拓人、白桃雄太、藏元慎也、川井田啓介、向原公介、豊川建二、今釜逸美、松本和久、橋口照人、曽我欣治
- Organizer
  第53回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19454
[Presentation] 左房内Pentraxin3の心房細動アブレーション前後の変化と左房機能関連因子との関連2023
- Author(s)
  鉛山かおり, 波野史典, 市来仁志, 鎌田博之, 吉元一成, 二宮雄一, 堀添善尚, 笠畑拓志, 政元いずみ, 山口宗一, 橋口照人, 大石充
- Organizer
  第87回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] 乾癬性関節炎における好中球関連マイクロRNAの検討2022
- Author(s)
  山口宗一、東裕子、竹之内和則、大山陽子、東貞行、藤崎知園子、田上聖徳、金蔵拓郎、橋口照人
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19454
[Presentation] 大動脈狭窄症での大動脈弁置換術による血流変化がもたらす血中マイクロRNAの変化2022
- Author(s)
  上田英昭, 山口宗一, 松本和久, 今釜逸美, 向原公介, 重久喜哉, 豊川建二, 川井田啓介, 立岡修治, 橋口照人, 曽我欣治
- Organizer
  第75回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] 大動脈狭窄症での大動脈弁置換術による血流変化がもたらす血中マイクロRNAの変化2022
- Author(s)
  上田英昭, 山口宗一, 松本和久, 今釜逸美, 向原公介, 重久喜哉, 豊川建二, 川井田啓介, 立岡修治, 橋口照人, 曽我欣治
- Organizer
  第75回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K19454
[Presentation] 乾癬性関節炎における好中球関連マイクロRNAの検討2022
- Author(s)
  山口宗一、東裕子、竹之内和則、大山陽子、東貞行、藤崎知園子、田上聖徳、金蔵拓郎、橋口照人
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24234
[Presentation] 血管平滑筋細胞石灰化のmiRNA依存性制御機構の検討2021
- Author(s)
  山口宗一, 上田英昭, 向原公介, 松本和久, 大川政士, 竹之内和則, 大山陽子, 東貞行, 藤崎知園子, 井本浩, 橋口照人
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19454
[Presentation] The significance of platelet dynamics in perioperative period of aortic valve replacement for aortic valve stenosis2021
- Author(s)
  Hideaki KANDA, Munekazu YAMAKUCHI, Kazuhisa MATSUMOTO, Kosuke MUKAIHARA, Yoshiya SHIGEHISA, Shuji TACHIOKA, Masashi OKAWA, Kazunori TAKENOUCHI, Yoko OYAMA, Teruto HASHIGUCHI, Yutaka IMOTO
- Organizer
  The Asian-Pacific Society on Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09130
[Presentation] 血中microRNA-126と血小板VEGF-Aの相互関連性についての検討2021
- Author(s)
  山口宗一, 向原公介, 上田英昭, 大川政士, 松本和久, 竹之内和則, 大山陽子, 東貞行, 藤崎知園子, 井本浩, 橋口照人
- Organizer
  日本医療検査医学会第54回大会
- Data Source
  KAKENHI-PROJECT-21K19454
[Presentation] 血清、血漿、血小板におけるVEGF-A 121、165アイソフォームの比較定量2021
- Author(s)
  大川政士, 山口宗一, 竹之内和則, 東貞行, 井上恵一, 山田晋吾, 橋口照人
- Organizer
  第22回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19454
[Presentation] 冠動脈バイパス術周術期における血小板内VEGFの推移2020
- Author(s)
  向原公介, 山口宗一, 松本和久, 上田英昭, 重久喜哉, 大川政士, 橋口照人, 井本浩
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] 冠動脈バイパス術周術期における血小板内VEGF-Aの変化についての検討2020
- Author(s)
  山口宗一, 向原公介, 上田英昭, 重久善哉, 大川政士, 松本和久, 竹之内和則, 大山陽子, 井本浩, 橋口照人
- Organizer
  第60回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] microRNAによる血管平滑筋石灰化制御の検討2020
- Author(s)
  山口宗一, 上田英昭, 大川政士, 向原公介, 重久善哉, 松本和久, 竹之内和則, 大山陽子, 東貞行, 藤崎知園子, 井本浩, 橋口照人
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] 冠動脈バイパス術周術期におけるmicroRNA-126についての検討2020
- Author(s)
  山口宗一, 向原公介, 上田英昭, 重久善哉, 大川政士, 松本和久, 竹之内和則, 大山陽子, 東貞行, 藤崎知園子, 井本浩, 橋口照人
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] マイクロRNAが血管平滑筋の石灰化に与える影響の解析2020
- Author(s)
  上田英昭, 山口宗一, 松本和久, 大川政士, 向原公介, 重久喜哉, 橋口照人, 井本浩
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] miR-375 attenuated innate immune response in bronchial epithelial cell through modulate of JAK2-STAT1 pathway2019
- Author(s)
  Koichi Takagi, Kentaro Machida, Takahiro Matsuyama, Kota Sakaue, Kiyotaka Kondo, Munekazu Yamakuchi, Teruto Hashiguchi, Hiromasa Inoue
- Organizer
  American Thoracic Society International Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] レジオネラ菌感染におけるマクロファージ様細胞U937のmicroRNAを介した応答機構2019
- Author(s)
  山口宗一, 郡山豊泰, 清水利昭, 竹之内和則, 大山陽子, 政元いずみ, 橋口照人
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19523
[Presentation] 大動脈弁狭窄症に対する大動脈弁置換術前後での末梢血、凝固系の検討2019
- Author(s)
  上田英昭、松本和久、山口宗一、竹之内和則、大山陽子、橋口照人、井本　浩
- Organizer
  第51回日本臨床検査自動化学学会
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] 大動脈弁狭窄症に対する大動脈弁置換術前後での末梢血、凝固系の検討2019
- Author(s)
  上田英昭、松本和久、山口宗一、竹之内和則、大山陽子、橋口照人、井本　浩
- Organizer
  第51回日本臨床検査自動化学学会
- Data Source
  KAKENHI-PROJECT-18K19523
[Presentation] miR-375 attenuated innate immune response in bronchial epithelial cell through modulate of JAK2-STAT1 pathway2019
- Author(s)
  Koichi Takagi, Kentaro Machida, Takahiro Matsuyama, Kota Sakaue, Kiyotaka Kondo, Munekazu Yamakuchi, Teruto Hashiguchi, Hiromasa Inoue
- Organizer
  American Thoracic Society International Conference 2019
- Data Source
  KAKENHI-PROJECT-18K19523
[Presentation] 未破裂肝細胞癌に対しマイクロスフィア塞栓後(DEB-TACE後)に肝切除を行った症例の病理学的検討2019
- Author(s)
  中島一壽, 小森園康二, 迫勝巳, 柴藤俊彦, 北薗正樹, 田中貞夫, 東貞行, 大山陽子, 竹之内和則, 山口宗一, 橋口照人
- Organizer
  日本臨床化学会
- Data Source
  KAKENHI-PROJECT-19K07892
[Presentation] レジオネラ菌感染におけるマクロファージ様細胞U937のmicroRNAを介した応答機構2019
- Author(s)
  山口宗一, 郡山豊泰, 竹之内和則, 大山陽子, 政元いずみ, 橋口照人
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] Chinese herbal medicine "Wu Ling San" had a renal protecting function in crystal induced granulomatous nephritis in rats.2019
- Author(s)
  Oyama Y, Tancharoen S, Ito T, Yamakuchi M, Higashi S, Hashiguchi T, Maruyama I.
- Organizer
  9th International Symposium DAMPS and HMGB1, Okayama, Japan 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09310
[Presentation] Regulation of von Willebrand factor release in endothelial cells2019
- Author(s)
  山口宗一, 竹之内和則, 大山陽子, 橋口照人
- Organizer
  第41回日本血栓止血学会学術集会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K19523
[Presentation] 大動脈弁狭窄症に対する大動脈弁置換術前後での末梢血、凝固系の検討2019
- Author(s)
  上田英昭, 松本和久, 山口宗一, 竹之内和則, 大山陽子, 橋口照人, 井本　浩
- Organizer
  第13 回日本血栓止血学会学術標準化委員会（SSC）シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] Regulation of von Willebrand factor release in endothelial cells2019
- Author(s)
  山口宗一, 竹之内和則, 大山陽子, 橋口照人
- Organizer
  第41回日本血栓止血学会学術集会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02734
[Presentation] Depleted PDGF-BB Kinetic in Post-Resection HCC Recurrence- A Risk2018
- Author(s)
  アリアルビベック、清水利昭、門野潤、風呂井彰、槐島健太郎、菰方輝夫、郡山千早、山口宗一、橋口照人、井本浩
- Organizer
  第65回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10130
[Presentation] PDGF-BB低値はHCC切除後再発のリスク因子なのか、単なる指標なのか?2018
- Author(s)
  アリアル・ビベック, 清水利昭, 門野潤, 風呂井彰, 槐島健太郎, 菰方輝夫, 郡山千早, 山口宗一, 橋口照人, 井本浩
- Organizer
  第65回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] The role of IL-13 in regulating pulmonary artery endothelial cell2018
- Author(s)
  Munekazu Yamakuchi, Koichi Takagi, Takahiro Matsuyama, Kiyotaka Kondo, Akifumi Uchida, Shunsuke Misono, Kazunori Takenouchi, Yoko Oyama, Hiromasa Inoue, Teruto Hashiguchi.
- Organizer
  APSTH
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10130
[Presentation] 好中球性皮膚疾患の病勢マーカーとしてのmicroRNAの検索2018
- Author(s)
  東　裕子、山口宗一、坂ノ上正直、福重智子、金蔵拓郎
- Organizer
  第48回日本皮膚免疫アレルギー学会総会学術大会
- Data Source
  KAKENHI-PROJECT-16K10130
[Presentation] The role of IL-13 in regulating pulmonary artery endothelial cell migration2018
- Author(s)
  Yamakuchi M, Takagi K, Matsuyama T, Kondo K, Uchida A, Misono S, Takenouchi K, Oyama Y, Inoue H, Hashiguchi T
- Organizer
  The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] 大動脈弁狭窄症でのシアストレスが血小板に与える影響2018
- Author(s)
  上田　英昭、重久　喜哉、向原　公介、井本　浩、山口　宗一、橋口　照人
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] ヒト巨核芽球細胞株における高血糖時のGLP-1受容体発現と機能の解析2018
- Author(s)
  郡山豊泰、山口宗一、竹之内和則、大山陽子、政元いずみ、橋口照人
- Organizer
  第65回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10130
[Presentation] The impact of endothelial marker on catheter ablation in patients with atrial fibrillation2018
- Author(s)
  Namino F, Yamakuchi M, Iriki Y, Okui H, Ichiki H, Maenosono R, Masamoto I, Hashiguchi T, Ohishi M, Maruyama I
- Organizer
  The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] Tracking the signaling pathway for the anti-angiogenic activity of proinflammatory factor TNF alpha2017
- Author(s)
  Sushil Panta、山口宗一、清水利昭、竹之内和則、大山陽子、郡山豊泰、古城　剛、橋口照人
- Organizer
  第62回日本臨床検査医学会　九州地方会　第28回日本臨床化学会　九州支部総会
- Place of Presentation
  久留米大学病院　筑水会館（福岡県久留米市）
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] Platelet derived growth factors predict HCC recurrence after partial hepatectomy in humans2017
- Author(s)
  Bibek Aryal、清水利昭、門野　潤、風呂井　彰、山口宗一、菰方輝夫、橋口照人、井本　浩
- Organizer
  第62回日本臨床検査医学会　九州地方会　第28回日本臨床化学会　九州支部総会
- Place of Presentation
  久留米大学病院　筑水会館（福岡県久留米市）
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] CalDAG-GEFI分子異常による血小板機能異常症2017
- Author(s)
  古城　剛、山口宗一、吉村明子、竹之内和則、伊藤隆史、清水利昭、大山陽子、郡山豊泰、波野史典、Sushil Panta 、松下昌風、丸山征郎、髙嶋　博、橋口照人
- Organizer
  第62回日本臨床検査医学会　九州地方会　第28回日本臨床化学会　九州支部総会
- Place of Presentation
  久留米大学病院　筑水会館（福岡県久留米市）
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] Platelet derived growth factors predict HCC recurrence after partial hepatectomy in humans2017
- Author(s)
  Bibek Aryal、清水利昭、門野　潤、風呂井　彰、山口宗一、菰方輝夫、橋口照人、井本　浩
- Organizer
  第62回日本臨床検査医学会　九州地方会　第28回日本臨床化学会　九州支部総会
- Place of Presentation
  久留米大学病院　筑水会館（福岡県久留米市）
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] Tracking the signaling pathway for the anti-angiogenic activity of proinflammatory factor TNF alpha2017
- Author(s)
  Sushil Panta、山口宗一、清水利昭、竹之内和則、大山陽子、郡山豊泰、古城　剛、橋口照人
- Organizer
  第62回日本臨床検査医学会　九州地方会　第28回日本臨床化学会　九州支部総会
- Place of Presentation
  久留米大学病院　筑水会館（福岡県久留米市）
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] CalDAG-GEFI分子異常による血小板機能異常症2017
- Author(s)
  古城　剛、山口宗一、吉村明子、竹之内和則、伊藤隆史、清水利昭、大山陽子、郡山豊泰、波野史典、Sushil Panta 、松下昌風、丸山征郎、髙嶋　博、橋口照人
- Organizer
  第62回日本臨床検査医学会　九州地方会　第28回日本臨床化学会　九州支部総会
- Place of Presentation
  久留米大学病院　筑水会館（福岡県久留米市）
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] Platelet-derived Growth Factors Predict HCC Recurrence After Partial Hepatectomy in Humans2017
- Author(s)
  Bibek Aryal, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Teruo Komokata, Munekazu Yamakuchi, Teruto Hashiguchi, Yutaka Imoto
- Organizer
  Twenty-eighth Japanese society of Clinical Chemistry
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] Intra-Platelet Serotonin After Partial Hepatectomy: A Candidate Predictor of HCC recurrence2017
- Author(s)
  Bibek Aryal, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Teruo Komokata, Munekazu Yamakuchi ,Teruto Hashiguchi ,Yutaka Imoto
- Organizer
  Sixth Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA) and the 29th meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery (JSHBPS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] 血液培養陽性データよりみる検出菌とその臨床背景2016
- Author(s)
  大山陽子, 竹之内和則, 古城剛, 郡山豊泰, 福山竜子, 山口宗一, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016
- Author(s)
  古城　剛、山口宗一、吉村明子、竹之内和則、伊藤隆史、清水利昭、大山陽子、郡山豊泰、Sushil Panta 、松下昌風、丸山征郎、髙嶋　博、橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム～I・RA・KA～（奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] Co-operation of TNFalpha and VEGF to regulate PAI-1 through synergistically upregulated p532016
- Author(s)
  Sushil Panta, Munekazu Yamakuchi, Toshiaki Shimizu, Kazunori Takenouchi, Yoko Oyama, Teruto Hashiguchi
- Organizer
  XXlllrd International Congress on Fibrinolysis & Proteolysis and XVlth International Workshop on Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  Nippondaira Hotel, Nihondaira, Shizuoka, Japan（静岡県静岡市）
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] High fat diet exacerbates imiquimod-induced psoriasis-like skin lesion by inducing IL-17A and inflammasomes in mice2016
- Author(s)
  Yuko　Higashi, Munekazu Yamakuchi, et al.
- Organizer
  Asia-Pacific Combined Dermatology Research Conference
- Place of Presentation
  Noosa,Queensland,Australia
- Year and Date
  2016-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10130
[Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016
- Author(s)
  古城剛, 山口宗一, 吉村明子, 竹之内和則, 伊藤隆, 清水利昭, 大山陽子, 郡山豊泰, Panta Sushil, 松下昌風, 丸山征郎, 高嶋博, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] L.pneumophila感染マクロファージ系細胞におけるmiRNAの役割2016
- Author(s)
  山口宗一, 郡山豊泰, 古城剛, 竹之内和則, 清水利昭, 大山陽子, 松下昌風, 橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム（奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] L.pneumophila感染マクロファージ系細胞におけるmiRNAの役割2016
- Author(s)
  山口宗一、郡山豊泰、古城　剛、竹之内和則、清水利昭、大山陽子、松下昌風、橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム～I・RA・KA～(奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] miRNAによる自然免疫制御機構の解明2016
- Author(s)
  山口宗一, 郡山豊泰, 向原公介, 重久喜哉, 古城剛, 清水利昭, 竹之内和則, 大山陽子, 井本浩, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Invited
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016
- Author(s)
  古城剛, 山口宗一, 吉村明子, 竹之内和則, 伊藤隆, 清水利昭, 大山陽子, 郡山豊泰, Panta Sushil, 松下昌風, 丸山征郎, 高嶋博, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] 血液培養陽性データよりみる検出菌とその臨床背景2016
- Author(s)
  大山陽子, 竹之内和則, 古城剛, 郡山豊泰, 福山竜子, 山口宗一, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] L.pneumophila感染マクロファージ系細胞におけるmiRNAの役割2016
- Author(s)
  山口宗一, 郡山豊泰, 古城剛, 竹之内和則, 清水利昭, 大山陽子, 松下昌風, 橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム（奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016
- Author(s)
  古城剛, 山口宗一, 吉村明子, 竹之内和則, 伊藤隆史, 清水利昭, 大山陽子, 郡山豊泰, Sushil Panta, 松下昌風, 丸山征郎, 高嶋博, 橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム（奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] L.pneumophila感染マクロファージ系細胞におけるmiRNAの役割2016
- Author(s)
  山口宗一、郡山豊泰、古城　剛、竹之内和則、清水利昭、大山陽子、松下昌風、橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム～I・RA・KA～(奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] miR-22の血管内皮細胞での役割の検討2016
- Author(s)
  竹中大喜, 山口宗一, 竹之内和則, 大山陽子, 清水利昭, 郡山豊泰, 古城剛, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016
- Author(s)
  古城　剛、山口宗一、吉村明子、竹之内和則、伊藤隆史、清水利昭、大山陽子、郡山豊泰、Sushil Panta 、松下昌風、丸山征郎、髙嶋　博、橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム～I・RA・KA～（奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] Co-operation of TNFalpha and VEGF to regulate PAI-1 through synergistically upregulated p532016
- Author(s)
  Sushil Panta, Munekazu Yamakuchi, Toshiaki Shimizu, Kazunori Takenouchi, Yoko Oyama, Teruto Hashiguchi
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop
- Place of Presentation
  Nippondaira Hotel（静岡県静岡市）
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] miRNAによる自然免疫制御機構の解明2016
- Author(s)
  山口宗一, 郡山豊泰, 向原公介, 重久喜哉, 古城剛, 清水利昭, 竹之内和則, 大山陽子, 井本浩, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016
- Author(s)
  古城剛, 山口宗一, 吉村明子, 竹之内和則, 伊藤隆史, 清水利昭, 大山陽子, 郡山豊泰, Sushil Panta, 松下昌風, 丸山征郎, 高嶋博, 橋口照人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム（奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] Co-operation of TNFalpha and VEGF to regulate PAI-1 through synergistically upregulated p532016
- Author(s)
  Sushil Panta, Munekazu Yamakuchi, Toshiaki Shimizu, Kazunori Takenouchi, Yoko Oyama, Teruto Hashiguchi
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop
- Place of Presentation
  Nippondaira Hotel（静岡県静岡市）
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] Co-operation of TNFalpha and VEGF to regulate PAI-1 through synergistically upregulated p532016
- Author(s)
  Sushil Panta, Munekazu Yamakuchi, Toshiaki Shimizu, Kazunori Takenouchi, Yoko Oyama, Teruto Hashiguchi
- Organizer
  XXlllrd International Congress on Fibrinolysis & Proteolysis and XVlth International Workshop on Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  Nippondaira Hotel, Nihondaira, Shizuoka, Japan（静岡県静岡市）
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05229
[Presentation] miR-22の血管内皮細胞での役割の検討2016
- Author(s)
  竹中大喜, 山口宗一, 竹之内和則, 大山陽子, 清水利昭, 郡山豊泰, 古城剛, 橋口照人
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] The significance of miRNA measurement in Legionella pneumophila infection2015
- Author(s)
  Toyoyasu Koriyama, Munekazu Yamakuchi, Tuyoshi Kojo, Ryuko Fukuyama, Masakaze Matsushita, Teruto Hashiguchi
- Organizer
  第64回日本医学検査学会
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] L.pneumophila感染単核系細胞におけるmiRNA解析2015
- Author(s)
  郡山豊泰、山口宗一、竹之内和則、大山陽子、清水利昭、橋口照人
- Organizer
  第62回日本臨床検査医学会
- Place of Presentation
  岐阜県岐阜市　長良川国際会議場
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] L.pneumophila感染単核系細胞におけるmiRNA解析2015
- Author(s)
  郡山豊泰、山口宗一、竹之内和則、大山陽子、清水利昭、橋口照人
- Organizer
  第62回日本臨床検査医学会
- Place of Presentation
  岐阜県岐阜市　長良川国際会議場
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] Regulation of Tumor Development by microRNAs- Do microRNAs link to cancer-associated thrombosis?2015
- Author(s)
  Munekazu Yamakuchi，Toshiaki Shimizu，Kazunori Takenouchi，Yoko Oyama，and Teruto Hashiguchi
- Organizer
  第37回日本血栓止血学会学術集会学術推進委員会（SPC）シンポジウム1
- Place of Presentation
  山梨県甲府市　甲府市総合市民会館
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] Platelet Mediated Angiogenesis During Liver regeneration After Partial　Hepatectomy In Humans.2015
- Author(s)
  Bibek Aryal, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Maki Inoue, Teruo Komokata, Munekazu Yamakuchi, Teruto Hashiguchi, Yutaka Imoto.
- Organizer
  第27回日本肝胆膵外科学会学術集会
- Place of Presentation
  東京都港区ホテルグランパシフィック LE DAIBA
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] The significance of miRNA measurement in Legionella pneumophila infection2015
- Author(s)
  Toyoyasu Koriyama, Munekazu Yamakuchi, Tuyoshi Kojo, Ryuko Fukuyama, Masakaze Matsushita, Teruto Hashiguchi
- Organizer
  第64回日本医学検査学会
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] A bidirectional role of platelet sequestered vascular endothelial growth factor-A in cancer and liver regeneration.2015
- Author(s)
  Bibek Aryal, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Maki Inoue, Teruo Komokata, Munekazu Yamakuchi, Teruto Hashiguchi, Yutaka Imoto.
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  岐阜県岐阜市長良川国際会議場
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K15197
[Presentation] Regulation of Tumor Development by microRNAs - Do microRNAs link to cancer-associated thrombosis?2015
- Author(s)
  Munekazu Yamakuchi，Toshiaki Shimizu，Kazunori Takenouchi，Yoko Oyama，and Teruto Hashiguchi
- Organizer
  第37回日本血栓止血学会学術集会学術推進委員会（SPC）シンポジウム1
- Place of Presentation
  山梨県甲府市　甲府市総合市民会館
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K15196
[Presentation] Loop -Mediated Isothermal Amplification (LAMP)法を用いたClostridium difficile toxinの検討2014
- Author(s)
  郡山豊泰、森明日華、古城剛、福山竜子、松下昌風、山口宗一、橋口照人
- Organizer
  第59回日本臨床検査医学会九州地方会第25回日本臨床化学会合同プログラム
- Place of Presentation
  熊本市医師会館
- Year and Date
  2014-03-15
- Data Source
  KAKENHI-PROJECT-25893192
[Presentation] アディポネクチンは新規炎症性アディポサイトカインHMGB1の分泌をJNK経由で阻害する2014
- Author(s)
  清水利昭、竹之内和則、山口宗一、橋口照人
- Organizer
  第59回日本臨床検査医学会九州地方会第25回日本臨床化学会合同プログラム
- Place of Presentation
  熊本市医師会館
- Year and Date
  2014-03-15
- Data Source
  KAKENHI-PROJECT-25893192
[Presentation] マイクロRNAによる直腸がん細胞の低酸素応答制御2013
- Author(s)
  山口宗一、清水利昭、竹ノ内和則、大山陽子、郡山豊康、橋口照人
- Organizer
  日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25893192
[Presentation] New adipocytokine HMGB1 inhibits insulin signaling in adipocyte and adiponectin suppresses this effect2013
- Author(s)
  Toshiaki Shimizu, Munekazu Yamakuchi, Shingo Yamada, Masanori Nakata, Teruto Hashiguchi, and Ikuro Maruyama
- Organizer
  The Merinoff world Congress
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-25893192
[Presentation] New Adipocytokine HMGB1 Inhibits Insulin Signaling in Adipocytes and Suppressed by Adiponection.2013
- Author(s)
  Shimizu T, Yamakuchi M, Nakata M, Hashiguchi T, Maruyama I.
- Organizer
  Merinoff World Congress 2013: HMGB1
- Place of Presentation
  New York
- Data Source
  KAKENHI-PROJECT-24659282
[Presentation] マイクロRNAによる直腸がん細胞の低酸素応答制御2013
- Author(s)
  山口宗一、清水利昭、竹ノ内和則、大山陽子、郡山豊康、橋口照人
- Organizer
  第60回日本臨床検査医学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25893192
[Presentation] マイクロRNAによる直腸がん細胞の低酸素応答制御2013
- Author(s)
  山口宗一、清水利昭、竹之内和則、大山陽子、橋口照人
- Organizer
  第60回　日本臨床検査医学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24659282
[Presentation] 直腸がんの血管新生を制御するマイクロRNAの検討
- Author(s)
  山口宗一, 清水利昭, 竹之内和則, 大山陽子, 郡山豊秦, 伊藤隆史, 橋口照人
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡(福岡国際会議場）
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] Hemophagocytosis as a process of fine tuning immune system in vivo
- Author(s)
  Shrestha Binita　伊藤隆史　郡山豊泰　竹之内和則　大山陽子　清水利昭　山口宗一　丸山征郎　橋口照人
- Organizer
  第61回　日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-24659282
[Presentation] マイクロRNAによる直腸がん血管新生制御機構の解明
- Author(s)
  山口宗一、清水利昭、竹之内和則、大山陽子、橋口照人
- Organizer
  第36回血栓止血学術集会
- Place of Presentation
  大阪（大阪国際交流センター）
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] Automatic Integration of All Laboratory Data in the Analysis Server Supporting
- Author(s)
  M. Yamakuchi, Y. Oyama, K. Takenouchi, T. Ito, T. Shimizu, M. Matsushita, T. Hashiguchi
- Organizer
  The 9th Cherry Bloosom Symposium
- Place of Presentation
  Yokohama, Japan（横浜赤レンガ倉庫1号館）
- Year and Date
  2014-04-17 – 2014-04-19
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] non-β細胞由来VEGF-Aはisletを構成しないインスリン産生細胞のsmall clustersを増加させる
- Author(s)
  竹之内和則、ビニタ・スレスタ、山口宗一、橋口照人
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京（東京大学本郷キャンパス）
- Year and Date
  2014-09-05 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] MIR-503 Modulation of NOS3 Signaling via RICTOR
- Author(s)
  Munekazu Yamakuchi, Teruto Hashiguchi, Charles J Lowenstei
- Organizer
  The 60th SSC
- Place of Presentation
  Milwaukee, USA
- Year and Date
  2014-06-23 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26293130
[Presentation] Novel Insight of B Cell-Derived VEGF-A: Fine Tuning the Immune Response Through Hemophagocytosis
- Author(s)
  Binita Shrestha, Takashi Ito, Naoki Miura, Kazunori Takenouchi, Sushil Panta, Munekazu Yamakuchi, Ikuro Maruyama, Teruto Hashiguchi
- Organizer
  44th Annual Meeting of the German Society for Immunology
- Place of Presentation
  BONN (Germany)
- Year and Date
  2014-09-17 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24659282

1. HASHIGUCHI Teruto (70250917)

# of Collaborated Projects: 29 results

# of Collaborated Products: 112 results
2. MARUYAMA Ikuro (20082282)

# of Collaborated Projects: 19 results

# of Collaborated Products: 11 results
3. OYAMA Yoko (20583470)

# of Collaborated Projects: 15 results

# of Collaborated Products: 60 results
4. TAKENOUCHI Kazunori (30646758)

# of Collaborated Projects: 13 results

# of Collaborated Products: 64 results
5. ITO Takashi (20381171)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
6. SHIMIZU Toshiaki (50468055)

# of Collaborated Projects: 6 results

# of Collaborated Products: 47 results
7. HARADA Yoichiro (80464147)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
8. Kanda Hideaki (50598274)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
9. Kojo Tsuyoshi (30837282)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 小浜祐行 (50837276)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. 大川政士 (90869322)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
12. 東貞行 (20866701)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
13. 阿辺山和浩 (30284897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. YAMAMOTO Mika (70791507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. Higashi Yuko (00381179)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
16. Imoto Yutaka (60274461)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
17. 川原幸一 (10381170)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 立岡修治 (30938311)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 向原公介 (40747903)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 曽我欣治 (50568607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. KANMURA Yuichi (30211189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NAKAJIMA Toshihiro (90260752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. IMAIZUMI Hitoshi (70203304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SAKAMOTO Taiji (10235179)

# of Collaborated Projects: 1 results

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YAMAKUCHI Munekazu 山口 宗一

山口 宗一 ヤマクチ ムネカズ

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circRNA-miRNAによる大動脈弁狭窄症病態解明とバイオマーカー創出の挑戦Principal Investigator

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The regulatory mechanism of vascular inflammation convergence by temporal and spatial axesPrincipal Investigator

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YAMAKUCHI Munekazu 山口宗一

山口宗一ヤマクチムネカズ