Fujiwara Hiroshi 藤原弘

… Alternative Names

FUJIWARA Hiroshi 藤原弘

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Researcher Number	20398291
Other IDs
Affiliation (Current)	2025: 三重大学, 医学系研究科, 産学官連携講座教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 三重大学, 医学系研究科, 産学官連携講座教授 2020: 三重大学, 医学系研究科, 産学官連携講座准教授 2018 – 2019: 三重大学, 医学系研究科, 特任准教授(研究担当) 2007 – 2017: Ehime University, 医学部附属病院, 講師 2008: Ehime University, 医学部・附属病院, 講師
Review Section/Research Field	Principal Investigator Hematology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 細胞免疫療法 / 白血病幹細胞 / 遺伝子改変T細胞 / 免疫記憶細胞 / T細胞受容体（TCR）遺伝子 / 遺伝子細胞免疫療法 / 養子免疫療法 / 白血病性幹細胞 / 遺伝子改変Tリンパ球 / 同種造血幹細胞移植 … More / 造血幹細胞移植 / off-the-shelf / 固形がん / persistence / CAR-T細胞 / 幹細胞様メモリーT細胞 / 同種γδ-T細胞 / 免疫療法 / 白血病 / 急性骨髄性白血病 / 骨髄性白血病 / 遺伝子改変ヘルパーT細胞 / ネオアンチゲン / キメラ型受容体（CAR）遺伝子 / キメラ型抗原受容体（CAR）遺伝子 / 抗腫瘍性T細胞ネットワーク / キメラ型抗原受容体遺伝子 / T細胞受容体遺伝子 / 抗白血病効果 / T細胞受容体遺伝子（TCR）遺伝子 / 細胞傷害性Tリンパ球（CTL） / 遺伝子導入 / T細胞受容体遺伝子(TCR)遺伝子 / T細胞受容体(TCR)遺伝子 / 同種造血幹細胞移植術 / がん抗原特異的T細胞受容体(TCR)遺伝子 / 細胞傷害性Tリンパ球(CTL) / 抗造血器悪性腫瘍ワクチン / 成人T細胞白血病リンパ腫(ATLL) / T細胞悪性リンパ腫 / 癌ワクチン / 細胞障害性Tリンパ球(CTL) / T細胞悪性リンパ / 造血幹細胞移植術 / がんワクチン / 細胞傷害性T リンパ球 / 成人T細胞白血病(ATL) / T 細胞性悪性リンパ腫 / 造血器悪性腫瘍 / 腫瘍免疫 … More Except Principal Investigator T細胞レセプター / 細胞傷害性T細胞 / 遺伝子治療 / 白血病 / WT1 / がん免疫療法 / CAR-T / 癌幹細胞 / 乳癌 / GD2 / 免疫療法 / CD16 / 抗体療法 / CAR-T細胞 / がん免疫 / ヒト化マウス / 幹細胞様メモリーT細胞 / CAR / γδ-T細胞 / 微小環境 / CAR-T細胞療法 / 多発性骨髄腫 / 乳癌幹細胞 / 病理診断 / トリプルネガティブ / 腫瘍浸潤リンパ球 / キメラ抗原受容体 / MAGE-A4 / TCR様抗体 / サイトメガロウイルス / 胸腺 / 非共有HLA / HLA半合致移植 / HLA拘束性T細胞 / HLA不適合造血細胞移植 / HLA拘束性 / HLA不適合移植 / ADCC / 遺伝子細胞治療 / NY-ESO1 / 骨髄腫 / がん免役療法 / NE-ESO1 / 遺伝子改変T細胞 / 移植・再生医療 / 免疫学 / 癌 / 再生医療 / 移植 / hTERT / Ｔ細胞レセプター / 白血病幹細胞 / 細胞障害性Ｔ細胞 / レトロウイルスベクター / ケモカイン / WTI / 肺がん / Aurora-A kinase / ケモカイン・ケモカインレセプター / T細胞レセプター遺伝子 Less

キメラ抗原受容体T細胞療法における標的抗原以外に対する免疫応答の意義
- Principal Investigator
  
  吉原哲
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hyogo Medical University
トリプルネガティブ乳癌におけるがん幹細胞を標的とする新規CAR-T療法の開発
- Principal Investigator
  
  齋藤佳菜子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Mie University
Analysis of tumor supressing function by Hybrid-TCR system
- Principal Investigator
  
  赤堀泰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Mie University
Aim to eliminate a bottleneck in the practical realization of anticancer immunotherapy with gene-modified allogeneic gammadelta T cells.Principal Investigator
- Principal Investigator
  
  藤原弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Mie University
幹細胞様メモリーT細胞分画に優れるγδ-T細胞の誘導法の検討
- Principal Investigator
  
  石原幹也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Mie University
Are T cells present restricted to the HLA not shared with patient and donor in HLA-mismatched transnplantation??
- Principal Investigator
  
  Ikegame Kazuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hyogo Medical University
Development of a novel immunotherapy targeting GD2 for the treatment of refractory breast cancer
- Principal Investigator
  
  齋藤佳菜子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Mie University
Development of novel anti-leukemia immunotherapy using neo-antigen specific CD4 helper T cellsPrincipal Investigator
- Principal Investigator
  
  Fujiwara Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Mie University
Immunotherapy for Adult T-cell Leukemia with novel chimeric antigen receptor T cells
- Principal Investigator
  
  Tanimoto Kazushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Ehime University
Therapeutic employment of leukemia-reactive CD4-CD8 T-cell network aiming at improved clinical efficacy.Principal Investigator
- Principal Investigator
  
  Fujiwara Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Ehime University
Development of novel gene-modified T cell therapy against chemotherapy-resistant leukemia
- Principal Investigator
  
  Yasukawa Masaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Ehime University
Development of the novel gene-immunotherapy using artificial CTL targeting leukemia stem cells
- Principal Investigator
  
  YASUKAWA Masaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Ehime University
Development of a novel antileukemia adoptive immunotherapy using leukemia-reactive gene-modified memory T cells.Principal Investigator
- Principal Investigator
  
  FUJIWARA HIROSHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Ehime University
Development of cancer immunotherapy using co-transfer of cancer-specific TCR gene and chemokine receptor gene
- Principal Investigator
  
  YASUKAWA Masaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Ehime University
Attempts to answer the crucial qeustion if the anti-tumor cellular immune system can eradicate leukemia stem cells-an analysis using humanized mouse system-Principal Investigator
- Principal Investigator
  
  FUJIWARA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Ehime University
Development of immune-cell therapy for human T cell lymphoma : Cancer vaccine in combination with allogeneic hematopoietic stem cell transplantation.Principal Investigator
- Principal Investigator
  
  FUJIWARA Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Ehime University

[Book] 遺伝子医学MOOK 31号「がん免疫療法-What’s now and what’s next?-」2017
- Author(s)
  藤原　弘
- Total Pages
  286
- Publisher
  株式会社メディカルドゥ
- ISBN
- Data Source
  KAKENHI-PROJECT-15K09506
[Book] Oncogene Proteins : Structure, Functions and Analyses.(Edited by Peter B Murphy and Jason R.)Oncogene proteins : Targets for cancer immuno-cell therapy2008
- Author(s)
  Fujiwara H, Yasukawa M
- Publisher
  Nova Publishers
- Data Source
  KAKENHI-PROJECT-19591121
[Book] Oncogene Proteins : Structure, Functions and Analyses. . Edited by Peter B Murphy and Jason R. Clarke、Chapter 2, Oncogene proteins : Targets for cancer immuno-cell therapy.2008
- Author(s)
  Fujiwara H, Yasukawa M
- Publisher
  Nova Publishers
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] CAR-T細胞療法の標的拡大へ向けた取り組み2024
- Author(s)
  藤原　弘
- Journal Title
  
  医学のあゆみ
  
  Volume: 288 Pages: 224-229
- Data Source
  KAKENHI-PROJECT-23K27455
[Journal Article] αβ-T cell receptor transduction gives superior mitochondrial function to γδ-T cells with promising persistence2023
- Author(s)
  Ishihara Mikiya、Miwa Hiroshi、Fujiwara Hiroshi、Akahori Yasushi、Kato Takuma、Tanaka Yoshimasa、Tawara Isao、Shiku Hiroshi
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 10 Pages: 107802-107802
- DOI
  10.1016/j.isci.2023.107802
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07228, KAKENHI-PROJECT-23K06714, KAKENHI-PROJECT-23K06740, KAKENHI-PROJECT-23K27455
[Journal Article] CAR-Modified Vγ9Vδ2 T Cells Propagated Using a Novel Bisphosphonate Prodrug for Allogeneic Adoptive Immunotherapy2023
- Author(s)
  Yizheng Wang, Linan Wang, Naohiro Seo, Satoshi Okumura, Tae Hayashi, Yasushi Akahori, Hiroshi Fujiwara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Yoshimasa Tanaka, Takuma Kato, Hiroshi Shiku
- Journal Title
  
  Int J Mol Sci
  
  Volume: 24 Issue: 13 Pages: 10873-10873
- DOI
  10.3390/ijms241310873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06714, KAKENHI-PROJECT-23K27455
[Journal Article] Therapeutic efficacy of the resorcylic acid lactone LL‐Z1640‐2 for adult T‐cell leukaemia/lymphoma2023
- Author(s)
  Oura M、Harada T、Oda A、Teramachi J、Nakayama A、Sumitani R、Inoue Y、Maeda Y、Sogabe K、Maruhashi T、Takahashi M、Fujii S、Nakamura S、Miki H、Nakamura M、Hara T、Yamagami H、Kurahashi K、Endo I、Hasegawa H、Fujiwara H、Abe M
- Journal Title
  
  eJHaem
  
  Volume: 4 Issue: 3 Pages: 667-678
- DOI
  10.1002/jha2.758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-23K21485, KAKENHI-PROJECT-23K24233, KAKENHI-PROJECT-23K27455
[Journal Article] Ganglioside GD2 Expression Is Associated With Unfavorable Prognosis in Early Triple-negative Breast Cancer2023
- Author(s)
  HIGASHI CHIHIRO、SAITO KANAKO、KOZUKA YUJI、YUASA HIROTO、NAKAMURA KAHO、ISHITOBI MAKOTO、ISHIHARA MIKIYA、MIZUNO TOSHIRO、TAWARA ISAO、FUJIWARA HIROSHI、OGAWA TOMOKO
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 9 Pages: 4045-4053
- DOI
  10.21873/anticanres.16593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08593, KAKENHI-PROJECT-18K06988, KAKENHI-PROJECT-23K27455
[Journal Article] 腫瘍特異的T細胞受容体遺伝子導入T細胞療法2023
- Author(s)
  藤原　弘
- Journal Title
  
  腫瘍内科
  
  Volume: 31 Pages: 468-473
- Data Source
  KAKENHI-PROJECT-23K27455
[Journal Article] A single-chain antibody generation system yielding CAR-T cells with superior antitumor function2021
- Author(s)
  Ochi Toshiki、Maruta Masaki、Tanimoto Kazushi、Kondo Fumitake、Yamamoto Toshihiro、Kurata Mie、Fujiwara Hiroshi、Masumoto Junya、Takenaka Katsuto、Yasukawa Masaki
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 273-273
- DOI
  10.1038/s42003-021-01791-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07376, KAKENHI-PROJECT-18H02839, KAKENHI-PROJECT-20H03719, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-21H02949, KAKENHI-PROJECT-21K15569
[Journal Article] Chromosomal defects and survival in adult T cell leukemia/lymphoma patients after allogeneic HSCT.2021
- Author(s)
  Nakano N, Utsunomiya A, Matsuo K, Yoshida N, Seto M, Ohshima K, Fujiwara H, Fuji S, Takatsuka1 Y, Ito A, Miyamoto T, Suehiro Y, Nakamae H, Sawayama Y, Yuasa M, Miyazaki Y, Ota S, Imada K, Fukuda T, Ichinohe T, Atsuta Y, Kato K.
- Journal Title
  
  Blood Advances
  
  Volume: 5(2) Issue: 2 Pages: 475-486
- DOI
  10.1182/bloodadvances.2020003639
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-21H02951
[Journal Article] Rinketsu Dictionary 免疫チェックポイント阻害剤2021
- Author(s)
  藤原　弘
- Journal Title
  
  臨床血液
  
  Volume: 62(2) Pages: 1-1
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] 固形がんに対する新たな複合免疫療法の考え方2020
- Author(s)
  藤原　弘
- Journal Title
  
  実験医学
  
  Volume: 38(2) Pages: 135-141
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] CAR-T細胞療法2020
- Author(s)
  藤原　弘
- Journal Title
  
  日本臨床
  
  Volume: 78 Pages: 261-266
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] Disseminated infection with novel human adenovirus (genotype 79) following allogeneic hematopoietic stem cell transplantation2020
- Author(s)
  Ikeda Yuichi、Tanimoto Kazushi、Azuma Taichi、Fujiwara Hiroshi、Ochi Toshiki、Asai Hiroaki、Nabe Shogo、Maruta Masaki、Takeuchi Kazuto、Yamanouchi Jun、Kitazawa Sohei、Takenaka Katsuto
- Journal Title
  
  Annals of Hematology
  
  Volume: - Issue: 9 Pages: 2421-2422
- DOI
  10.1007/s00277-020-04151-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08713, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-19K08816
[Journal Article] TCR受容体遺伝子改変T細胞療法の問題点と改善策 -エピトープ・HLA複合体を標的とした遺伝子改変T細胞療法-2020
- Author(s)
  藤原　弘
- Journal Title
  
  腫瘍内科
  
  Volume: 26(6) Pages: 1-7
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] Use of RNA Interference with TCR Transfer to Enhance Safety and Efficiency.2020
- Author(s)
  Casey NP, Kyte JA, Fujiwara H
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2115 Pages: 327-349
- DOI
  10.1007/978-1-0716-0290-4_18
- ISBN
  9781071602898, 9781071602904
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] Improving TCR affinity on 293T cells2019
- Author(s)
  Ohta Rieko、Demachi-Okamura Ayako、Akatsuka Yoshiki、Fujiwara Hiroshi、Kuzushima Kiyotaka
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 466 Pages: 1-8
- DOI
  10.1016/j.jim.2018.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07285, KAKENHI-PROJECT-18K08341, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-16K07192, KAKENHI-PROJECT-17K07238
[Journal Article] 急性リンパ性白血病に対するCAR-T細胞療法-その現状と展望2019
- Author(s)
  藤原　弘
- Journal Title
  
  医学のあゆみ
  
  Volume: 268(1) Pages: 54-60
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] 再発・難治性多発性骨髄腫に対するCAR-T細胞療法の開発状況と今後の展開2019
- Author(s)
  藤原　弘
- Journal Title
  
  血液内科
  
  Volume: 78(1) Pages: 50-55
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] 急性リンパ性白血病に対するCAR-T細胞療法2019
- Author(s)
  藤原　弘
- Journal Title
  
  Pharma Medica
  
  Volume: 37(10) Pages: 49-53
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] Cytomegalovirus reactivation is associated with increased mortality more than 100 days after allogeneic hematopoietic stem cell transplantation for adult T-cell leukemia-lymphoma.2019
- Author(s)
  Sawayama Y, Itonaga H, Fukushima T, Nakano N, Fujiwara H, Utsunomiya A, Fukuda T, Miyamoto T, Eto T, Miyashita K, Nakamae H, Ogata M, Yamanoha A, Miyazaki Y, Kanda J, Atsuta Y, Kato K; ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.
- Journal Title
  
  American Journal of Hematology
  
  Volume: 94(5) Issue: 5 Pages: 143-146
- DOI
  10.1002/ajh.25438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-17K16189
[Journal Article] A retrospective analysis of haplo-identical HLA-mismatch hematopoietic transplantation without posttransplantation cyclophosphamide for GVHD prophylaxis in patients with adult T-cell leukemia-lymphoma.2019
- Author(s)
  Yoshimitsu M, Utsunomiya A, Fuji S, Fujiwara H, Fukuda T, Ogawa H, Takatsuka Y, Ishitsuka K, Yokota A, Okumura H, Ishii K, Nishikawa A, Eto T, Yonezawa A, Miyashita K, Tsukada J, Tanaka J, Atsuta Y, Kato K.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: 印刷中 Issue: 8 Pages: 1266-1274
- DOI
  10.1038/s41409-018-0400-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09882, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-19K08818
[Journal Article] Direct comparisoin of target-reactivity and cross-reactivity induced by CAR-and BiTE-redirected T cells for the development of antibody-based T-cell therapy.2019
- Author(s)
  Masaki Maruta, Toshiki Ochi, Kazushi Tanimoto, Hiroaki Asai, et al.
- Journal Title
  
  Scientific reports
  
  Volume: 9 Issue: 1 Pages: 13293-13293
- DOI
  10.1038/s41598-019-49834-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08330, KAKENHI-PROJECT-18K08331, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-18H02839, KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-17K09957
[Journal Article] 白血病細胞のCAR-T耐性獲得機序としてのtrogocytosisとCAR遺伝子細胞内ドメインの共刺激シグナル分子2019
- Author(s)
  藤原　弘
- Journal Title
  
  腫瘍内科
  
  Volume: 24(6) Pages: 684-690
- NAID
  40022108625
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] 急性骨髄性白血病に対するCAR-T細胞療法の展望2019
- Author(s)
  藤原　弘
- Journal Title
  
  血液内科
  
  Volume: 79(1) Pages: 12-18
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] AMLに対する免疫療法の可能性2018
- Author(s)
  丸田雅樹、谷本一史、藤原　弘
- Journal Title
  
  血液内科
  
  Volume: 76(2) Pages: 216-221
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] 遺伝子改変技術・ゲノム編集技術のCAR-T細胞療法への応用2018
- Author(s)
  藤原　弘
- Journal Title
  
  Pharma Medica
  
  Volume: 36(11) Pages: 45-50
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] An unusual, CD4 and CD8 dual-positive, CD25 negative, tumor cell phenotype in a patient with adult T-cell leukemia/lymphoma2018
- Author(s)
  Casey Nicholas、Fujiwara Hiroshi、Azuma Taichi、Murakami Yuichi、Yoshimitsu Makoto、Masamoto Izumi、Nawa Yuichiro、Yamanouchi Jun、Narumi Hiroshi、Yakushijin Yoshihiro、Hato Takaaki、Yasukawa Masaki
- Journal Title
  
  Leukemia & Lymphoma
  
  Volume: 印刷中 Issue: 11 Pages: 2740-2742
- DOI
  10.1080/10428194.2018.1439168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09957, KAKENHI-PROJECT-15H04858, KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-18K08361
[Journal Article] 次世代型CAR-T細胞療法の展望2018
- Author(s)
  藤原　弘
- Journal Title
  
  Bio INDUSTRY
  
  Volume: 35(7) Pages: 47-56
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination.2018
- Author(s)
  Akahori Y, Wang L, Yoneyama M, Seo N, Okumura S, Miyahara Y, Amaishi Y, Okamoto S, Mineno J, Ikeda H, Maki T, Fujiwara H, Akatsuka Y, Kato T, Shiku H.
- Journal Title
  
  Blood. 2018 Sep 13;132(11):
  
  Volume: 132 Issue: 11 Pages: 1134-1145
- DOI
  10.1182/blood-2017-08-802926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08341, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-18K19474, KAKENHI-PROJECT-18K19584, KAKENHI-PROJECT-18H02872, KAKENHI-PROJECT-16K09533
[Journal Article] AMLに対する免疫療法の可能性2018
- Author(s)
  丸田雅樹, 谷本一史, 藤原　弘
- Journal Title
  
  血液内科
  
  Volume: 76 Pages: 216-221
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] Follow-up of a randomised phase II study of chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma: impact on allogeneic haematopoietic stem cell transplantation2018
- Author(s)
  Ishida T、Jo T、Takemoto S、Suzushima H、Suehiro Y、Choi I、Yoshimitsu M、Saburi Y、Nosaka K、Utsunomiya A、Kobayashi Y、Yamamoto K、Fujiwara H、Ishitsuka K、Yoshida S、Taira N、Imada K、Kato K、Moriuchi Y、Yoshimura K、Takahashi T、Tobinai K、Ueda R
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中 Issue: 3 Pages: 479-483
- DOI
  10.1111/bjh.15123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09957, KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-16H04713, KAKENHI-PROJECT-16K09865
[Journal Article] びまん性大細胞型B細胞リンパ腫に対するCD19を標的とするCAR-T細胞療法の開発現状と今後の展開2018
- Author(s)
  藤原　弘
- Journal Title
  
  血液内科
  
  Volume: 77(4) Pages: 481-487
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] がん微小環境と腫瘍免疫の最前線2018
- Author(s)
  藤原　弘
- Journal Title
  
  臨床血液
  
  Volume: 59(10) Pages: 35-44
- NAID
  130007496778
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] Dasatinib-induced anti-leukemia cellular immunity through a novel subset of CD57 positive helper/cytotoxic CD4 T cells in chronic myelogenous leukemia patients.2018
- Author(s)
  Watanabe N, Takaku T, Takeda K, Shirane S, Toyota T, Koike M, Noguchi M, Hirano T, Fujiwara H, Komatsu N.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 108(6) Issue: 6 Pages: 588-597
- DOI
  10.1007/s12185-018-2517-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08361
[Journal Article] AMLに対する免疫療法の可能性2018
- Author(s)
  丸田雅樹、谷本一史、藤原　弘
- Journal Title
  
  血液内科
  
  Volume: 76 Pages: 216-221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09957
[Journal Article] Peripheral T-cell lymphoma cell line T8ML-1 highlights conspicuous targeting of PVRL2 by t(14;19)(q11.2;q13.3)2017
- Author(s)
  Ehrentraut Stefan、Nagel Stefan、Pommerenke Claudia、Dirks Wilhelm G.、Quentmeier Hilmar、Kaufmann Maren、Meyer Corinna、Zaborski Margarete、Geffers Robert、Fujiwara Hiroshi、Drexler Hans G.、MacLeod Roderick A. F.
- Journal Title
  
  Haematologica
  
  Volume: 102 Issue: 9 Pages: e356-e359
- DOI
  10.3324/haematol.2017.168203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09957, KAKENHI-PROJECT-15K09506
[Journal Article] ATLに対するmogamulizumab併用遺伝子修飾T細胞療法の可能性2017
- Author(s)
  藤原　弘、丸田雅樹
- Journal Title
  
  血液内科
  
  Volume: 74 Pages: 51-57
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09957
[Journal Article] T-cell Receptor Signaling Activates an ITK/NF-κB/GATA-3 axis in T-cell Lymphomas Facilitating Resistance to Chemotherapy.2017
- Author(s)
  Wang T, Lu Y, Polk A, Chowdhury P, Zamalloa CM, Fujiwara H, Suemori K, Beyersdorf N, Hristov AC, Lim MS, Bailey NG, Wilcox RA.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: in print Issue: 10 Pages: 2506-2515
- DOI
  10.1158/1078-0432.ccr-16-1996
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] 遺伝子改変T細胞療法におけるCAR-T細胞療法の位置づけ2017
- Author(s)
  藤原　弘
- Journal Title
  
  血液フロンティア
  
  Volume: 27 Pages: 31-39
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09957
[Journal Article] TCR/CAR遺伝子導入T細胞を用いた血液腫瘍に対する養子免疫療法2017
- Author(s)
  藤原　弘
- Journal Title
  
  血液内科
  
  Volume: 74 Pages: 24-30
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] ATLに対するmogamulizumab併用遺伝子修飾T細胞療法の可能性2017
- Author(s)
  藤原　弘、丸田雅樹
- Journal Title
  
  血液内科
  
  Volume: 74（1） Pages: 51-57
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] ATLに対するmogamulizumab併用遺伝子修飾T細胞療法の可能性2017
- Author(s)
  藤原　弘, 丸田雅樹
- Journal Title
  
  血液内科
  
  Volume: 74 Pages: 51-57
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] 遺伝子改変T細胞療法におけるCAR-T細胞療法の位置づけ2017
- Author(s)
  藤原　弘
- Journal Title
  
  血液フロンティア
  
  Volume: 27 Pages: 31-39
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] 遺伝子改変T細胞による癌免疫療法2017
- Author(s)
  丸田雅樹, 藤原　弘
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 68 Pages: 601-606
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] Safety and persistence of WT1-specific T-cell receptor gene-transduced lymphocytes in patients with AML and MDS.2017
- Author(s)
  Tawara I, Kageyama S, Miyahara Y, Fujiwara H, Nishida T, Akatsuka Y, Ikeda H, Tanimoto K, Terakura S, Murata M, Inaguma Y, Masuya M, Inoue N, Kidokoro T, Okamoto S, Tomura D, Chono H, Nukaya I, Mineno J, Naoe T, Emi N, Yasukawa M, Katayama N, Shiku H.
- Journal Title
  
  Blood
  
  Volume: 130 Issue: 18 Pages: 1985-1994
- DOI
  10.1182/blood-2017-06-791202
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09307, KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-17K09949, KAKENHI-PROJECT-17K09957, KAKENHI-PROJECT-15H04858, KAKENHI-PROJECT-15H04918, KAKENHI-PROJECT-15K09497, KAKENHI-PROJECT-15K09498, KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-15K10093
[Journal Article] Dismal outcome of allogeneic hematopoietic stem cell transplantation for relapsed adult T-cell leukemia/lymphoma, a Japanese nation-wide study.2017
- Author(s)
  Fujiwara H, Fuji S, Wake A, Kato K, Takatsuka Y, Fukuda T, Taguchi J, Uchida N, Miyamoto T, Hidaka M, Miyazaki Y, Tomoyose T, Onizuka M, Takanashi M, Ichinohe T, Atsuta Y, Utsunomiya A; ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 52 (3) Issue: 3 Pages: 484-488
- DOI
  10.1038/bmt.2016.313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-17K09957
[Journal Article] Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice.2016
- Author(s)
  Najima Y, Tomizawa-Murasawa M, Saito Y, Watanabe T, Ono R, Ochi T, Suzuki N, Fujiwara H, Ohara O, Shultz LD, Yasukawa M, Ishikawa F.
- Journal Title
  
  Blood
  
  Volume: 127(6) Issue: 6 Pages: 722-734
- DOI
  10.1182/blood-2014-10-604777
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-15H04858, KAKENHI-PLANNED-24111009
[Journal Article] Novel Immunotherapy for Adult T-cell Leukemia/Lymphoma; Targeting Aurora-A kinase.2016
- Author(s)
  Casey NP, Fujiwara H, Ochi T, Yasukawa M.
- Journal Title
  
  Oncoimmunology
  
  Volume: 5(11) Issue: 11 Pages: e1239006-e1239006
- DOI
  10.1080/2162402x.2016.1239006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] Multicenter Phase II Study of Lenalidomide in Relapsed or Recurrent Adult T-Cell Leukemia-Lymphoma: ATLL-002.2016
- Author(s)
  Ishida T, Fujiwara H, Nosaka K, Taira N, Abe Y, Imaizumi Y, Moriuchi Y, Jo T, Ishizawa K, Tobinai K, Tsukasaki K, Ito S, Yoshimitsu M, Otsuka M, Ogura M, Midorikawa S, Ruiz W, Ohtsu T.
- Journal Title
  
  J Clin Oncol.
  
  Volume: ３４ Issue: 34 Pages: 4086-4093
- DOI
  10.1200/jco.2016.67.7732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04713, KAKENHI-PROJECT-15K09506
[Journal Article] がん抗原特異的TCRを用いた養子細胞免疫療法2016
- Author(s)
  谷本一史、藤原　弘
- Journal Title
  
  臨床血液
  
  Volume: 57(11) Pages: 2355-2364
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] がん抗原特異的TCRを用いた細胞免疫療法2016
- Author(s)
  谷本一史、藤原　弘
- Journal Title
  
  臨床血液
  
  Volume: 57(7)
- NAID
  130005433498
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] Usefulness of Low-Dose Splenic Irradiation prior to Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Elderly Patients with Myelofibrosis.2016
- Author(s)
  Matsubara E, Yamanouchi J, Kitazawa R, Azuma T, Fujiwara H, Hato T, Yasukawa M.
- Journal Title
  
  Case Reports in Hematology
  
  Volume: 2016 Pages: 8751329-8751329
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] Development of engineered T cells expressing a chimeric CD16-CD3ζ receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia2016
- Author(s)
  Tanaka H, Yasukawa M, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 22 Issue: 17 Pages: 4405-4416
- DOI
  10.1158/1078-0432.ccr-15-2714
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04858, KAKENHI-PROJECT-15K09506
[Journal Article] A functionally superior second-generation vector expressing an Aurora Kinase-A-specific T-cell receptor for anti-leukaemia adoptive immunotherapy2016
- Author(s)
  Casey, N.P., Yasukawa M, et al.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 6 Pages: e0156896-e0156896
- DOI
  10.1371/journal.pone.0156896
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04858, KAKENHI-PROJECT-15K09506
[Journal Article] Early application of related SCT might improve clinical outcome in adult T-cell leukemia/lymphoma.2016
- Author(s)
  Fuji S, Fujiwara H, Nakano N, Wake A, Inoue Y, Fukuda T, Hidaka M, Moriuchi Y, Miyamoto T, Uike N, Taguchi J, Eto T, Tomoyose T, Kondo T, Yamanoha A, Ichinohe T, Atsuta Y, Utsunomiya A; ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 51(2) Issue: 2 Pages: 205-211
- DOI
  10.1038/bmt.2015.265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] Development of engineered T cells expressing a chimeric CD16-CD3ζ receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia2016
- Author(s)
  Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett J, Yasukawa M.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: in press
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04858
[Journal Article] Antileukemia multifunctionality of CD4+ T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer.2015
- Author(s)
  Fujiwara H*, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M.
- Journal Title
  
  Lｅｕｋｅｍｉａ
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] Optimization of T-cell reactivity y exploiting TCR chain centricity for the purpose of safe and effective antitumor TCR gene therapy.2015
- Author(s)
  Ochi T, Nakatsugawa M, Chamoto K, Tanaka S, Yamashita Y, Guo T, Fujiwara H*, Yasukawa M, Butler M, Hirano N.
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy.2015
- Author(s)
  Ochi T, Nakatsugawa M, Chamoto K, Tanaka S, Yamashita Y, Guo T, Fujiwara H, Yasukawa M, Butler MO, Hirano N.
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 3(9) Issue: 9 Pages: 1070-1081
- DOI
  10.1158/2326-6066.cir-14-0222
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-15H04858, KAKENHI-PROJECT-26670467
[Journal Article] 腫瘍関連抗原特異的T細胞受容体を発現させたTリンパ球を用いる癌遺伝子治療2015
- Author(s)
  藤原　弘
- Journal Title
  
  血液フロンティア
  
  Volume: 25(5) Pages: 61-70
- Data Source
  KAKENHI-PROJECT-15K09506
[Journal Article] Antileukemia multifunctionality of CD4+ T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer2015
- Author(s)
  Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, and Yasukawa M
- Journal Title
  
  Leukemia
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390245
[Journal Article] Dose-intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma: a randomized phase II study.2015
- Author(s)
  Ishida T, Jo T, Takemoto S, Suzushima H, Uozumi K, Yamamoto K, Uike N, Saburi Y, Nosaka K, Utsunomiya A, Tobinai K, Fujiwara H, Ishitsuka K, Yoshida S, Taira N, Moriuchi Y, Imada K, Miyamoto T, Akinaga S, Tomonaga M, Ueda R
- Journal Title
  
  Br J Haematol
  
  Volume: 未定 Issue: 5 Pages: 672-682
- DOI
  10.1111/bjh.13338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390254, KAKENHI-PROJECT-24591426, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-25290058
[Journal Article] Antileukemia multifunctionality of CD4(+) T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer.2015
- Author(s)
  Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M.
- Journal Title
  
  Leukemia
  
  Volume: 29(12) Issue: 12 Pages: 2393-2401
- DOI
  10.1038/leu.2015.155
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506, KAKENHI-PROJECT-15H04858, KAKENHI-PROJECT-26670467, KAKENHI-PROJECT-26830109
[Journal Article] Adoptive T-cell therapy for hematological malignancies using T cells gene-modified to express tumor antigen-specific receptors.2014
- Author(s)
  Fujiwara H
- Journal Title
  
  International Journal of Hematology
  
  Volume: 99 Issue: 2 Pages: 123-131
- DOI
  10.1007/s12185-013-1493-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] Genetically engineered fixed K562 cells: potent “off the shelf” antigen presenting cells for generating virus specific T cells.2014
- Author(s)
  Tanimoto K, Muranski P, Miner S, Fujiwara H*, Kajigaya S, Keyvanfer K, Hensel N, Barrett AJ, Melenhorst JJ.
- Journal Title
  
  Cytotherapy
  
  Volume: 16(1) Issue: 1 Pages: 135-146
- DOI
  10.1016/j.jcyt.2013.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] 腫瘍抗原特異的T細胞受容体遺伝子導入を用いた遺伝子改変T細胞による抗白血病養子免疫療法2014
- Author(s)
  藤原　弘
- Journal Title
  
  臨床血液
  
  Volume: 55(6) Pages: 657-669
- NAID
  130004501866
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] TCR/CAR遺伝子導入T細胞を用いた養子免疫療法2014
- Author(s)
  藤原　弘
- Journal Title
  
  細胞
  
  Volume: 46(2) Pages: 409-413
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] Gene-Modified Human α/β-T Cells Expressing a Chimeric CD16-CD3ζ Receptor as Adoptively Transferable Effector Cells for Anticancer Monoclonal Antibody Therapy.2014
- Author(s)
  Yasukawa M, et al.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 2 Issue: 3 Pages: 249-262
- DOI
  10.1158/2326-6066.cir-13-0099-t
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12F02773, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24591426, KAKENHI-PROJECT-26670467
[Journal Article] Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression.2014
- Author(s)
  Rowan AG, Suemori K, Fujiwara H, Yasukawa M, Tanaka Y, Taylor GP, Bangham C.
- Journal Title
  
  Retrovirology
  
  Volume: 11 Pages: 116-116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390245
[Journal Article] Adoptive immunotherapy for hematological malignancies using T cells gene-modified to express tumor antigen-specific receptors.2014
- Author(s)
  Fujiwara H
- Journal Title
  
  Pharmaceuticals
  
  Volume: 7(12) Issue: 12 Pages: 1049-1068
- DOI
  10.3390/ph7121049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] 遺伝子改変T細胞による血液腫瘍に対する養子免疫療法2014
- Author(s)
  藤原　弘
- Journal Title
  
  臨床血液
  
  Volume: 55(10) Pages: 2162-2174
- NAID
  130004696111
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression.2014
- Author(s)
  Rowan AG, Suemori K, Fujiwara H*, Yasukawa M, Tanaka Y, Taylor GP, Bangham　C.
- Journal Title
  
  Retrovirology
  
  Volume: 11(1) Pages: 116-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] TCR/CAR遺伝子導入T細胞を用いた白血病・リンパ腫に対する養子免疫療法2014
- Author(s)
  藤原　弘
- Journal Title
  
  血液フロンティア
  
  Volume: 24(11) Pages: 45-53
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] Cutaneous lesions of blastic plasmacytoid dendritic cell neoplasm.2014
- Author(s)
  Suemori K, Fujiwara H*, Niiya T, Yasukawa M.
- Journal Title
  
  Internal Medicine
  
  Volume: 53(4) Pages: 339-340
- NAID
  130003392659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591426
[Journal Article] Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury2014
- Author(s)
  Asai H, Fujiwara H, Kitazawa S, Kobayashi N, Ochi T, Miyazaki Y, Ochi F, Akatsuka Y, Okamoto S, Mineno J, Kuzushima K, Ikeda H, Shiku H, Yasukawa M
- Journal Title
  
  J Hematol Oncol.
  
  Volume: 7 Issue: 1 Pages: 3-3
- DOI
  10.1186/1756-8722-7-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12F02773, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24390300, KAKENHI-PROJECT-24591426, KAKENHI-PROJECT-24591435, KAKENHI-PROJECT-26670467
[Journal Article] Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia.2013
- Author(s)
  Yasukawa M, et al.
- Journal Title
  
  Blood
  
  Volume: 121 Issue: 24 Pages: 4894-4901
- DOI
  10.1182/blood-2012-11-465971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02773, KAKENHI-PROJECT-23591419, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24591426
[Journal Article] Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model.2013
- Author(s)
  Iwami K, Natsume A, Ohno M, Ikeda H, Mineno J, Nukaya I, Okamoto S, Fujiwara H, Yasukawa M, Shiku H, Wakabayashi T.
- Journal Title
  
  Neuro Oncol.
  
  Volume: 15 Issue: 6 Pages: 747-758
- DOI
  10.1093/neuonc/not007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24249073, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24390300, KAKENHI-PROJECT-24591426
[Journal Article] Co-introduced functional CCR2 potentiates in vivo anti-lung cancer func tionality mediated by T cells double gene-modified to express WT1-specific T-cell receptor.2013
- Author(s)
  Yasukawa M, et al.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 2 Pages: e56820-e56820
- DOI
  10.1371/journal.pone.0056820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02773, KAKENHI-PROJECT-23659489, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24591426
[Journal Article] HLA-restricted presentation of WT1 tumor antigen in B-lymphoblastoid cell lines established using a maxi-EBV system.2012
- Author(s)
  Kanda, T, et al.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: 19 Issue: 8 Pages: 566-571
- DOI
  10.1038/cgt.2012.34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659489, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24590567, KAKENHI-PROJECT-24591426
[Journal Article] Aurora kinase A-specific T-cell receptor gene transfer redirects T-lymphocytes to display effective anti-leukemia reactivity2012
- Author(s)
  Nagai, K., Fujiwara, H., Yasukawa, M., 他9名
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 368-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Defucosylated anti-CCR4 monoclonal antibody (KW-0761) for relapsed adult T-cell leukemia-lymphoma a multicenter phase II study2012
- Author(s)
  Ishida T.
- Journal Title
  
  J Clin Oncol
  
  Volume: 30(8) Issue: 8 Pages: 837-42
- DOI
  10.1200/jco.2011.37.3472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300333, KAKENHI-PROJECT-22689029, KAKENHI-PROJECT-24590422, KAKENHI-PROJECT-24591426, KAKENHI-PROJECT-221S0001
[Journal Article] A promising vector for TCR gene therapy: differential effect of siRNA, 2A peptide, and disulfide bond on the introduced TCR expression.2012
- Author(s)
  Okamoto S, et al.
- Journal Title
  
  Mol Ther Nucleic Acids.
  
  Volume: 18 Pages: e63-e63
- DOI
  10.1038/mtna.2012.52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659489, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24390300, KAKENHI-PROJECT-24591426
[Journal Article] Aurora kinase A-specific T-cell receptor gene transfer redirects T-lymphocytes to display effective anti-leukemia reactivity2012
- Author(s)
  Kozo Nagai, et al
- Journal Title
  
  Blood
  
  Volume: 119(2) Issue: 2 Pages: 368-76
- DOI
  10.1182/blood-2011-06-360354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245, KAKENHI-PROJECT-23591419, KAKENHI-PROJECT-23659489, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24591426
[Journal Article] Aurora kinase A-specific T-cell receptor gene transfer redirects T-lymphocytes to display effective anti-leukemia reactivity2012
- Author(s)
  Nagai K, Ochi T, Fujiwara H, An J, Shirakata T, Mineno J, Kuzushima K, Shiku H, Melenhorst J, Gostic E, Price D. A., Ishii E, Yasukawa M
- Journal Title
  
  Blood.
  
  Volume: 119(2) Pages: 368-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] 遺伝子改変T細胞を用いた悪性腫瘍に対する細胞免疫療法2011
- Author(s)
  藤原弘
- Journal Title
  
  臨床血液
  
  Volume: 52(5) Pages: 243-255
- NAID
  10029424729
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] T細胞レセプター遺伝子を用いたがん免疫遺伝子治療のトランスレーショナルリサーチ2011
- Author(s)
  越智俊元、藤原弘、安川正貴
- Journal Title
  
  愛媛医学
  
  Volume: 30(1) Pages: 6-12
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Activation of T-cell receptor signaling in peripheral T-cell lymphoma cells plays an important role in the development of lymphoma-associated hemophagocytosis2011
- Author(s)
  An J, Fujiwara H, Suemori K, Niiya T, Azuma T, Tanimoto K, Ochi T, Akatsuka Y, Mineno J, Ozawa H, Ishikawa F, Kuzushima K, Yasukawa M
- Journal Title
  
  Int J Hematol.
  
  Volume: 93(2) Pages: 176-185
- NAID
  10029533085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Activation of T-cell receptor signaling in peripheral T-cell lymphoma cells plays an important role in the development of lymphoma-associated hemophagocytosis2011
- Author(s)
  An, J., Fujiwara, H., Yasukawa, M., 他10名
- Journal Title
  
  Int. J. Hemattol
  
  Volume: 93 Pages: 176-185
- NAID
  10029533085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Gemcitabine enhances Wilms' tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response2011
- Author(s)
  Takahara A, Koido S, Ito M, Nagasaki E, Sagawa Y, Iwamoto T, Komita H, Ochi T, Fujiwara H, Yasukawa M, Mineno J, Shiku H, Nishida S, Sugiyama H, Tajiri H, Homma S
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 60(9) Pages: 1289-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Gemcitabine enhances Wilms' tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response2011
- Author(s)
  Takahara, A., Fujiwara, H., Yasukawa, M., 他13名
- Journal Title
  
  Cancer Immunol. Immunother.
  
  Volume: 60 Pages: 1289-1297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Requisite considerations for successful adoptive immunotherapy with engineered T-lymphocytes using tumor antigen-specific T-cell receptor gene transfer2011
- Author(s)
  Ochi T, Fujiwara H, Yasukawa M
- Journal Title
  
  Expert Opin Biol Ther.
  
  Volume: 11(6) Pages: 699-713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked anti-leukemia reactivity and safety2011
- Author(s)
  Ochi T, Fujiwara H, Okamoto S, An J, Nagai K, Shirakata T, Mineno J, Kuzushima K, Shiku H, Yasukawa M
- Journal Title
  
  Blood.
  
  Volume: 118(6) Pages: 1495-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Requisite considerations for successful adoptive immunotherapy with engineered T lymphocytes using tumor antigen-specific T-cell receptor genetransfer2011
- Author(s)
  Ochi, T., Fujiwara, H., Yasukawa M.
- Journal Title
  
  Expert Opin.Biol.Ther.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Feasibility of gene-immunotherapy using WT1-specific T-cell receptor gene transfer for infant acute lymphoblastic leukemia with MLL gene rearrangement2011
- Author(s)
  Nagai K, Fujiwara H, Ochi T, Okamoto S, Mineno J, Shiku H, Koh K, Sugita K, Ishii E, Yasukawa M
- Journal Title
  
  Blood Cancer Journal
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked anti-leukemia reactivity and safety2011
- Author(s)
  Ochi, T., Fujiwara, H., Yasukawa, M., 他7名
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 1495-1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Adoptive T-cell immunotherapy using T-cell receptor gene transfer : aiming at a cure for cancer2011
- Author(s)
  Yasukawa, M. Fujiwara, H., 他1名
- Journal Title
  
  Immunotherapy
  
  Volume: 3 Pages: 135-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Requisite considerations for successful adoptive immunotherapy with engineered T lymphocytes using tumor antigen-specific T-cell receptor gene transfer2011
- Author(s)
  Ochi, T., Fujiwara, H. and Yasukawa, M.
- Journal Title
  
  Expert Opin. Biol. Ther.
  
  Volume: 11 Pages: 699-713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Feasibility of gene-immunotherapy using WT1-specific T-cell receptor gene transfer for infant acute lymphoblastic leukemia with MLL gene rearrangement2011
- Author(s)
  Nagai, K., Fujiwara, H., Yasukawa, M., 他7名
- Journal Title
  
  Blood Cancer J
  
  Volume: 1 Pages: 10-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] 白血病に対する細胞免疫療法(総説)2010
- Author(s)
  越智俊元, 藤原弘, 安川正貴
- Journal Title
  
  Medical Science Digest
  
  Volume: 36 Pages: 884-887
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Allo-HLA reactivity of leukemia-specific cytotoxic T lymphocytes2010
- Author(s)
  Yasukawa M, Nagai K, Fujiwara H, Ochi T, Akatsuka Y, Mineno J and Shiku H
- Journal Title
  
  Blood
  
  Volume: (e-Letters)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] がんワクチン療法の現状と課題(総説)2010
- Author(s)
  永井功造・藤原弘・安川正貴
- Journal Title
  
  血液・腫瘍科
  
  Volume: 60(1) Pages: 106-112
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Application of adoptive T-cell therapy using tumor antigen-specific T-cell receptor gene transfer for the treatment of human leukemia2010
- Author(s)
  Ochi T, Fujiwara H, Yasukawa M
- Journal Title
  
  J Biomed Biotechnol.
  
  Pages: 521248-521248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice2010
- Author(s)
  Shultz LD, Saito Y, Najima Y, Tanaka S, Ochi T, Tomizawa M, Doi T, Sone A, Suzuki N, Fujiwara H, Yasukawa M, Ishikawa F
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 107(29) Pages: 13022-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Generation of functional human T cells with HLA-restricted immune responses in HLA-class I expressing NOD/SCID/IL2rγ^<null> humanized mice2010
- Author(s)
  Shultz, L., Fujiwara, H., Yasukawa, M., 他9名
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 13022-13027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Allo-HLA reactivity of leukemia-specific cytotoxic T lymphocytes. e-Letter2010
- Author(s)
  Yasukawa, M. Fujiwara, H., 他5名
- Journal Title
  
  Blood Accessed April
  
  Volume: 19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Relapse of renal cell carcinoma with disappearance of HLA class I following hTERT peptide vaccination2010
- Author(s)
  Yasukawa, M., Ochi, T., Fujiwara, H.
- Journal Title
  
  Ann.Oncol.
  
  Volume: 21 Pages: 2122-2124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] HLA class I binding of HBZ determines outcome in HTLV-1 infection2010
- Author(s)
  MacNamara, A., Fujiwara, H., Yasukawa, M., 他7名
- Journal Title
  
  PLoS Pathog
  
  Volume: 6 Pages: 1001117-1001117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR2010
- Author(s)
  Okamoto, S, Fujiwara, H., Yasukawa, M., 他4名
- Journal Title
  
  Cancer Res
  
  Volume: 69 Pages: 9003-9011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Derivative(1 ; 18)(q10 ; q10) in essential thrombocythemia2010
- Author(s)
  Azuma, T., Fujiwara, H., Yasukawa M., 他6名
- Journal Title
  
  Cancer Genet. Cytogenet
  
  Volume: 199 Pages: 62-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Relapse of renal cell carcinoma with disappearance of HLA class I following hTERT peptide vaccination2010
- Author(s)
  Yasukawa, M. Fujiwara, H., 他2名
- Journal Title
  
  Ann. Oncol
  
  Volume: 21 Pages: 2122-2124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Subtypes of familial hemophagocytic lymphohistiocytosis in Japan based on genetic and functional analyses of cytotoxic T lymphocytes2010
- Author(s)
  Nagai, K., Fujiwara, H., Yasukawa, M., 他9名
- Journal Title
  
  PLoS One
  
  Volume: 5 Pages: 14173-14173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] ウイルス関連悪性リンパ腫の発症機構(総説)2010
- Author(s)
  藤原弘・安川正貴
- Journal Title
  
  血液・腫瘍科
  
  Volume: 60(2) Pages: 157-163
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Aurora-A kinase : a novel target of cellular immunotherapy for leukemia2009
- Author(s)
  Ochi T, Fujiwara H, Suemori K, Azuma T, Yakushijin Y, Hato T, Kuzushima K, Yasukawa M.
- Journal Title
  
  Blood 113
  
  Pages: 66-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] HBZ is an immunogenic protein but not a target antigen for HTLV-1-specific cytotoxic T lymphocytes2009
- Author(s)
  Suemori, K., Fujiwara, H., Yasukawa, M., 他5名
- Journal Title
  
  J. Gen. Virol
  
  Volume: 90 Pages: 1806-1811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients.2009
- Author(s)
  Kozako T, Fujiwara H, et al.
- Journal Title
  
  Leukemia 23
  
  Pages: 375-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients2009
- Author(s)
  Kozako T, Yoshimitsu M, Fujiwara H, Masamoto I, Horai S, White I, Akimoto M, Suzuki S, Matsushita K, Uozumi K, Tei C, Arima N.
- Journal Title
  
  Leukemia 23
  
  Pages: 375-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] 抗ATL腫瘍免疫抗原としてのHBZの検討 WS1-2-32009
- Author(s)
  小川泰司, 藤原弘, 他
- Journal Title
  
  第31回日本造血細胞移植学会総会抄録集 113
  
  Pages: 179-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Aurora-A kinase : A novel target of cellular immunotherapy for leukemia2009
- Author(s)
  Ochi, T., Fujiwara, H., Yasukawa, M., 他5名
- Journal Title
  
  Blood
  
  Volume: 113 Pages: 66-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Identification of a novel epitope derived from CML66 which is recognized by anti-leukaemia cytotoxic T lymphocytes2009
- Author(s)
  Suemori, K., Fujiwara, H., Yasukawa, M., 他6名
- Journal Title
  
  Br. J. Haematol
  
  Volume: 146 Pages: 115-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR2009
- Author(s)
  Okamoto S, Mineno J, Ikeda H, Fujiwara H, Yasukawa M, Shiku H, Kato I
- Journal Title
  
  Cancer Res.
  
  Volume: 69(23) Pages: 9003-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] 造血器腫瘍関連抗原の同定と臨床応用2009
- Author(s)
  藤原弘
- Journal Title
  
  臨床血液
  
  Volume: 50(5) Pages: 340-351
- NAID
  10024959712
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Aurora-A kinase : a novel target both for cellular immunotherapy and molecular target therapy against human leukemia2009
- Author(s)
  Ochi T, Fujiwara H, Yasukawa M
- Journal Title
  
  Expert Opin Ther Targets.
  
  Volume: 13(12) Pages: 1399-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591245
[Journal Article] Clinical efficacy of WT1 peptide vaccination in patients with acute myelogenous leukemia and myelodysplastic syndrome2009
- Author(s)
  Yasukawa, M. Fujiwara, H., 他5名
- Journal Title
  
  Am. J. Hematol
  
  Volume: 84 Pages: 314-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390294
[Journal Article] Identification of a novel epitope derived from OML66 which is recognized by anti-leukaemia cytotoxic T lymphocytes.2009
- Author(s)
  Suemori K, Fujiwara H, et al.
- Journal Title
  
  British Journal of Haematology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Aurora-A kinase : a novel target of cellular immunotherapy for leukemia.2009
- Author(s)
  Ochi T, Fujiwara H, et al.
- Journal Title
  
  Blood 113
  
  Pages: 66-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Allogeneic stem cell transplantation for refractory adult adult T-cell leukemia using a non T-cell-depleted HLA-incompatible family donor graft,with reference to the grown-up child donor to parent recipient setting report of a pilot study2008
- Author(s)
  Fujiwara H, et. al.
- Journal Title
  
  International Journal of Hematology 87
  
  Pages: 319-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Identification of an epitope derived from CML66, a novel tumor-associated antigen expressed broadly in human leukemia, recognized by human leukocyte antigen-A*2402-restricted cytotoxic T lymphocytes.2008
- Author(s)
  Suemori K, Fujiwara H, Ochi T, Azuma T, Yamanouchi J, Narumi H, Yakushijin Y, Hato T, Hasegawa H, Yasukawa M.
- Journal Title
  
  Cancer Science 99
  
  Pages: 1414-9
- NAID
  10024008706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Allogeneic stem cell transplantation for refractory adult T-cell leukemia using a non-T-cell-depleted HLA-incompatible family donor graft, with reference to the grown-up child donor to parent recipient setting : report of a pilot study2008
- Author(s)
  Fujiwara H, Ozaki A, Yoshimitsu M, Hamada H, Masamoto I, Matsushita K, Yasukawa M, Tei C.
- Journal Title
  
  International Journal of Hematology 87
  
  Pages: 319-326
- NAID
  10021256219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Allogeneic Stem cell transplantation for refractory adult T-cell leukemia using a non-T-cell-depleted HLA-incompatible family donor graft, with reference to the grown-up child donor to parent recipient setting : report of a pilot study.2008
- Author(s)
  Fujiwara H, Ozaki A, et al.
- Journal Title
  
  International Journal of Hematology 87
  
  Pages: 319-326
- NAID
  10021256219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Identification of an epitope derived from CML66, a novel tumor-associated antigen broadly expressed in huma n leukemia,recognized by HLA-A^*2402-restricted cytotoxic T lymphocytes2008
- Author(s)
  Suemori K, Fujiwara H, et. al.
- Journal Title
  
  Cancer Science (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Case of a patient with Philadelphia-chromosome-positive acute lymphoblastic leukemia relapsed after myeloablative allogeneic hematopoietic stem cell transplantation treated successfully with imatinib and sequential donor lymphocyte infusions.2008
- Author(s)
  Yoshimitsu M, Fujiwara H, et al.
- Journal Title
  
  International Journal of Hematology 88
  
  Pages: 331-335
- NAID
  10023970479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Identification of an epitope derived from CML66, a novel tumor-associated antigen expressed broadly in human leukemia, recognized by human leukocyte antigen-A*2402-restricted cytotoxic T lymphocytes.2008
- Author(s)
  Suemori K, Fujiwara H, et al.
- Journal Title
  
  Cancer Science 99
  
  Pages: 1414-1419
- NAID
  10024008706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Journal Article] Identification of a novel epitope derived from CML66 which is recognized by anti-leukaemia cytotoxic T lymphocytes
- Author(s)
  Suemori K, Fujiwara H, Ochi T, Azuma T, Yamanouchi J, Narumi H, Yakushijin Y, Hato T, Yasukawa M.
- Journal Title
  
  British Journal of Haematology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591121
[Patent] GD2結合性分子2019
- Inventor(s)
  珠玖洋、三輪啓志、赤堀泰、藤原弘、古川鋼一、古川圭子、大海雄介
- Industrial Property Rights Holder
  珠玖洋、三輪啓志、赤堀泰、藤原弘、古川鋼一、古川圭子、大海雄介
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-142358
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K08361
[Patent] 抗原受容体2019
- Inventor(s)
  珠玖洋、三輪啓志、赤堀泰、藤原弘
- Industrial Property Rights Holder
  珠玖洋、三輪啓志、赤堀泰、藤原弘
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-142357
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K08361
[Patent] T細胞レセプター及び該レセプターをコードする核酸2010
- Inventor(s)
  藤原弘, 他
- Industrial Property Rights Holder
  国立大学法人愛媛大学, 他
- Filing Date
  2010-10-07
- Overseas
- Data Source
  KAKENHI-PROJECT-21591245
[Patent] T細胞レセプター及び該レセプターをコードする核酸2010
- Inventor(s)
  安川正貴、藤原弘、越智俊元、峰野純一、加藤郁之進
- Industrial Property Rights Holder
  国立大学法人愛媛大学、タカラバイオ(株)
- Acquisition Date
  2010-10-07
- Overseas
- Data Source
  KAKENHI-PROJECT-21591245
[Patent] CML66抗原によるがんワクチンの製造2007
- Inventor(s)
  安川正貴、藤原弘、末盛浩一郎
- Industrial Property Rights Holder
  愛媛大学
- Industrial Property Number
  2007-179843
- Filing Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-19591121
[Patent] HLA-A2拘束性抗原ペプチドおよびその用途(Aurora-Aペプチド)2007
- Inventor(s)
  安川正貴、藤原弘、越智俊元
- Industrial Property Rights Holder
  愛媛大学
- Industrial Property Number
  2007-139441
- Filing Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Development of novel adoptive immunotherapy with gene-modified allogeneic γδ-T cells.2023
- Author(s)
  Hiroshi Fujiwara
- Organizer
  Cell and Gene Therapy Days, 2023: Advancing and translating cellular immunotherapy.
- Invited
- Data Source
  KAKENHI-PROJECT-23K27455
[Presentation] 遺伝子改変同種γδ-T細胞を用いるがん免疫療法の開発2023
- Author(s)
  藤原　弘
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27455
[Presentation] αβ-TCR transduction into γδ-T cells enhances mitochondrial function2023
- Author(s)
  Mikiya Ishihara, Hiroshi Miwa, Hiroshi Fujiwara, Yasushi Akahori, Takuma Kato, Yoshimasa Tanaka, Isao Tawara and Hiroshi Shiku
- Organizer
  The 10th International γδ T cell conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06740
[Presentation] Updates on the latest developments in CAR-T therapies.2023
- Author(s)
  Hiroshi Fujiwara
- Organizer
  The 2023 Korean Society of Hematology, International Conference and 64th Annual Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27455
[Presentation] がんに対する遺伝子改変同種γδ-T細胞療法開発2023
- Author(s)
  藤原　弘
- Organizer
  第27回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27455
[Presentation] CAR-T療法に関する最新の世界情勢2021
- Author(s)
  藤原　弘
- Organizer
  第43回日本造血細胞移植学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] TCR遺伝子導入T細胞療法-エピトープ・HLA複合体特異的免疫細胞療法の視点から-2020
- Author(s)
  藤原　弘
- Organizer
  第58回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] CAR-T bioengineering for solid cancers; choice of therapeutic targets and immune cells engineered.2020
- Author(s)
  Hiroshi Fujiwara.
- Organizer
  第79回日本癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] CTL誘導とGVHD/GVL -TCR-T/CAR-T療法時代の同種造血幹細胞移植-2020
- Author(s)
  藤原　弘
- Organizer
  第56回日本移植学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] 固形がんに対する新規GD2特異的CAR遺伝子導入アロγ/δ-T細胞療法の開発2020
- Author(s)
  藤原弘、赤堀泰、三輪啓志、王立楠、日向千咲、瀬尾尚宏、宮原慶裕、田中義正、大海雄介、、古川圭子、古川鋼一、森実飛鳥、髙橋淳、池田裕明、珠玖洋
- Organizer
  第82回日本日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] 新規GD2特異的CAR遺伝子導入アロγ/δ-T細胞の開発2020
- Author(s)
  藤原弘、赤堀泰、三輪啓志、王立楠、日向千咲、大海雄介、宮原慶裕、田中義正、古川圭子、古川鋼一、珠玖洋
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] Combined immunotherapy using CAR-T cells and immune checkpoint inhibitors.2019
- Author(s)
  藤原弘
- Organizer
  第11回日本血液疾患免疫療法学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] Novel treatment strategy using HTLV-1 p40Tax-specific TCR gene-modified allogeneic gamma/delta-T cells for the treatment of adult T-cell leukemia/lymphoma.2019
- Author(s)
  Fujiwara H., Okumura S., Fujii K., Miyahara Y, Tawara I., Jo T., Tanaka Y., Tanaka Y., Ikeda H., Shiku H
- Organizer
  The 10th JSH International Symposium 2019 in Ise-Shima,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] Genetically re-directed /-T cells towards cancer antigens: another promising player of anticancer immunotherapy?2019
- Author(s)
  藤原弘
- Organizer
  第23回日本がん免疫学会総会　シンポジウム4　がん免疫細胞療法
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] Novel cellular immunotherapy using allogeneic Vgamma9/delta2-T cells gene-modified to express HTLV-1 P40Tax-specific TCR for the treatment of adult T cell leukemia.2019
- Author(s)
  Fujiwara H., Okumura S., Fujii K., Miyahara Y., Linan W., Tawara I., Jo T., Tanaka Y., Tanaka Y., Ikeda H., M.D., Shiku H.
- Organizer
  The 61st American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] Adoptive immunotherapy using gene-modified T cells to express myeloma-associated Ag-reactive receptors against r/r MM.2019
- Author(s)
  藤原弘
- Organizer
  第44回日本骨髄腫学会シンポジウム3-2
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] CAR-T therapy against B-cell malignancy; Up-dated2019
- Author(s)
  藤原弘
- Organizer
  第6回　免疫細胞療法研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] Development of TCR-like scFv zG CAR that specifically recognizes MAGE-4230-239/HLA-A*02:01 complex.2019
- Author(s)
  Akahori Y., Kato Y., Miyahara Y., Amaike C., Wang L., Takuma K., Fujiwara H., Miwa H., Ikeda H., Shiku H.
- Organizer
  2nd International Conference of Lymphocyte Engineering.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] TCR/CAR gene-modified allogeneic gamma/delta-T cells for the treatment of hematological cancers.2019
- Author(s)
  Fujiwara H., Okumura H., Miwa H., Akahori Y., Miyahara Y., Linan W., Tawara I., Jo T., Tanaka Y., Tanaka Y., Ikeda H., Shiku H.
- Organizer
  2nd International Conference of Lymphocyte Engineering.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] がん微小環境と腫瘍免疫の最前線2018
- Author(s)
  藤原　弘
- Organizer
  第80回日本血液学会学術集会教育講演EL-2-4A
- Invited
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] 発作性夜間血色素尿症患者に発症した悪性リンパ腫はリツキシマブの効果が増強する2018
- Author(s)
  朝井洋晶, 竹内一人, 池田祐一, 越智俊元, 谷本一史, 山之内純, 東太地, 藤原弘, 羽藤高明, 安川正貴, 薬師神芳洋
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] 改変抗体を応用した難治性骨髄腫に対する新規T細胞免疫療法の開発2018
- Author(s)
  越智俊元, 丸田雅樹, 谷本一史, 朝井洋晶, 斉藤卓, 藤原弘, 今村健志, 竹中克斗, 安川正貴
- Organizer
  第10回血液疾患免疫療法学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] 本態性血小板血症患者での出血症状の検討2018
- Author(s)
  山之内純, 羽藤高明, 池田祐一, 朝井洋晶, 越智俊元, 谷本一史, 竹内一人, 東太地, 藤原弘, 薬師神芳洋, 安川正貴
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] 改変抗体を用いた難治性骨髄腫に対する新規T細胞免疫療法の開発2018
- Author(s)
  丸田雅樹, 越智俊元, 谷本一史, 東太地, 齋藤卓, 藤原弘, 今村健志, 安川正貴
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Development of anti-myeloma immunotherapy by exploiting modified antibodies specific for A2/NY-ESO-1.2018
- Author(s)
  Ochi, T., Maruta, M., Tanimoto, K., Asai, H., Saitou, T., Yakushijin, Y., Fujiwara, H., Imamura,T., Takenaka, K., Yasukawa, M.
- Organizer
  The fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] 難治性骨髄腫を標的とした改変抗体T細胞免疫療法2018
- Author(s)
  丸田雅樹, 越智俊元, 谷本一史, 東太地, 斉藤卓, 藤原弘, 今村健志, 安川正貴
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] ATRAおよびATOにて治療したcryptic APLの一例2018
- Author(s)
  谷本一史, 越智俊元, 東太地, 朝井洋晶, 池田祐一, 竹内一人, 山之内純, 藤原弘, 羽藤高明, 安川正貴
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] 難治性骨髄腫を標的とした改変抗体T細胞免疫療法2018
- Author(s)
  丸田雅樹, 越智俊元, 谷本一史, 東太地, 斉藤卓, 藤原弘, 今村健志, 安川正貴
- Organizer
  第80回　日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08361
[Presentation] Strategically Comprehensive Immunotherapy Utilizing Modified Antibody Targeting NY-ESO-1 for Myeloma.2017
- Author(s)
  Maruta, M., Ochi, T., Fujiwara, H., Yasukawa, M.
- Organizer
  The 8th JSH International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Development of a novel ADCC effector cell; an application for mogamulizumab therapy against ATL2017
- Author(s)
  藤原弘,Casey N, 谷本一史, 岡本幸子, 峰野純一, 葛島清隆, 珠玖　洋, Barrett AJ, 安川正貴
- Organizer
  第39回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] A2/NY-ESO-1特異的改変抗体を応用した多発性骨髄腫に対する新規免疫療法の開発2017
- Author(s)
  丸田雅樹，越智俊元，谷本一史，東太地，藤原弘，安川正貴
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] A2/NY-ESO-1特異的改変抗体を応用した多発性骨髄腫に対する新規免疫療法の開発2017
- Author(s)
  丸田雅樹，越智俊元，谷本一史，東太地，藤原弘，安川正貴
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Gene-modified T cell therapy for hematological malignancy: Current status and future prospective in Japan.2017
- Author(s)
  Fujiwara H.
- Organizer
  The 8th JSH International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Development of T-Cell Therapy By Exploiting Modified Antibodies Specific for A2/NY-ESO-1 for Refractory Myeloma2017
- Author(s)
  Masaki Maruta, Toshiki Ochi, Kazushi Tanimoto, Taichi Azuma, Hiroshi Fujiwara, and Masaki Yasukawa
- Organizer
  59th American Society of Hematology Annual Meeting
- Data Source
  KAKENHI-PROJECT-15H04858
[Presentation] Combined administration of gene-modified T cells expressing chimeric CD16-CD3ζ receptors with mogamulizmab for the treatment of ATL.2017
- Author(s)
  Fujiwara H, Tanimoto K, Maurta M, Takeuchi K, Azuma T, Yasukawa M.
- Organizer
  18th International Conference on Human Retrovirology, HTLV and Related Viruses Tokyo 2017
- Place of Presentation
  Chiyoda-ku, Tokyo, Japan, Hotel Grand Arc Hanzomon
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] A2/NY-ESO-1特異的改変抗体を応用した骨髄腫に対する新たな免疫療法の開発2017
- Author(s)
  越智俊元, 丸田雅樹, 谷本一史, 東太地, 藤原弘, 安川正貴
- Organizer
  第9回血液疾患免疫療法学会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Development of T-cell therapy by exploiting modified antibodies specific for A2/NY-ESO-1 for refractory myeloma.2017
- Author(s)
  Maruta, M., Ochi, T., Tanimoto, K., Azuma, T., Fujiwara, H., Yasukawa, M.
- Organizer
  The 59th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] 成人T細胞白血病治療コンセプトの進展20172017
- Author(s)
  藤原弘
- Organizer
  平成29年度　第1回　四国・愛媛臨技　血液検査研究班研修会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Combined administration of gene-modified T cells expressing chimeric CD16-CD3Z receptors with mogamulizmab for the treatment of ATL.2017
- Author(s)
  Fujiwara H, Tanimoto K, Maurta M, Takeuchi K, Azuma T, Yasukawa M.
- Organizer
  18th International Conference on Human Retrovirology, HTLV and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Redirecting T cells towards epitope/HLA complexes for the treatment of hematological cancers.2017
- Author(s)
  Fujiwara H.
- Organizer
  第21回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 大量の乳び胸水を契機に診断された節性濾胞辺縁帯リンパ腫の一例2017
- Author(s)
  谷本一史, 東太地, 朝井洋晶, 池田祐一, 越智俊元, 竹内一人,山之内純, 薬師神芳洋, 藤原弘, 羽藤高明, 安川正貴
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Combined administration of gene-modified T cells expressing chimeric CD16-CD3zeta receptors with mogamulizmab for the treatment of ATL.2017
- Author(s)
  Fujiwara H, Tanimoto K, Maurta M, Takeuchi K, Azuma T, Yasukawa M.
- Organizer
  18th International Conference on Human Retrovirology, HTLV and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Strategically Comprehensive Immunotherapy Utilizing Modified Antibody Targeting NY-ESO-1 for Myeloma.2017
- Author(s)
  Maruta, M., Ochi, T., Fujiwara, H., Yasukawa, M.
- Organizer
  The 8th JSH International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Phase I/II clinical trial of Aurora kinase peptide vaccination for the treatment of refractory or relapsed acute myeloid leukemia.2017
- Author(s)
  Fujiwara H, Tanimoto K, Ochi T, Kuzushima K, Yasukawa M
- Organizer
  43th Annual Meeting of the European Group for Blood and Marrow Transplantation
- Place of Presentation
  Marseille, France
- Year and Date
  2017-03-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] A2/NY-ESO-1特異的改変抗体を応用した骨髄腫に対する新たな免疫療法の開発2017
- Author(s)
  越智俊元, 丸田雅樹, 谷本一史, 東太地, 藤原弘, 安川正貴
- Organizer
  第9回血液疾患免疫療法学会
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] ATL治療戦略20172017
- Author(s)
  藤原　弘
- Organizer
  徳島Hematology Forum
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Development of immunotherapy for myeloma utilizing T cells redirected with modified antibodies specific for NY-ESO-1.2017
- Author(s)
  Ochi, T., Maruta, M., Tanimoto, K., Azuma, T., Fujiwara, H., Yasukawa M.
- Organizer
  The 36th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Anti-myeloma immunotherapy utilizing T cells redirected by modified antibodies targeting NY-ESO-1.2017
- Author(s)
  Ochi, T., Maruta, M., Fujiwara, H., Yasukawa M.
- Organizer
  第42回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 両側乳房への孤立性病変にて再発した急性リンパ性白血病の一例2017
- Author(s)
  丸田雅樹, 谷本一史, 東太地, 朝井洋晶, 池田祐一, 越智俊元, 竹内一人, 山之内純, 藤原弘, 薬師神芳洋, 羽藤高明, 安川正貴
- Organizer
  第56回日本血液学会　中国四国地方会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Development of a novel ADCC effector cell; an application for mogamulizumab therapy against ATL.2017
- Author(s)
  藤原弘,Casey N, 谷本一史, 岡本幸子, 峰野純一, 葛島清隆, 珠玖　洋, Barrett AJ, 安川正貴
- Organizer
  第39回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] NY-ESO-1を認識する改変抗体を応用した骨髄腫に対する新たな包括的免疫療法の開発2017
- Author(s)
  越智俊元, 丸田雅樹, 藤原弘, 安川正貴
- Organizer
  第54回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 治療抵抗性多発性骨髄腫に対する免疫療法- 加速度的に開発が進む新規抗がん剤に抵抗性を獲得した骨髄腫を打破できるか？2017
- Author(s)
  藤原　弘
- Organizer
  Hiroshima Myeloma Forum
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Development of T-cell therapy by exploiting modified antibodies specific for A2/NY-ESO-1 for refractory myeloma.2017
- Author(s)
  Maruta, M., Ochi, T., Tanimoto, K., Azuma, T., Fujiwara, H., Yasukawa, M.
- Organizer
  The 59th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 改変抗体を応用した多発性骨髄腫に対する新たな免疫療法の開発2017
- Author(s)
  丸田雅樹, 越智俊元, 藤原弘, 安川正貴
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Development of immunotherapy for myeloma utilizing T cells redirected with modified antibodies specific for NY-ESO-1.2017
- Author(s)
  Ochi, T., Maruta, M., Tanimoto, K., Azuma, T., Fujiwara, H., Yasukawa M.
- Organizer
  The 36th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 造血幹細胞移植におけるTCR/CAR遺伝子改変エフェクター細胞の位置づけ2017
- Author(s)
  藤原　弘
- Organizer
  第16回先端医療フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Strategically Comprehensive Immunotherapy Employing Modified Antibody Targeting NY-ESO-1 for Multiple Myeloma.2017
- Author(s)
  丸田雅樹，越智俊元，谷本一史，東太地，藤原弘，安川正貴
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Phase I/II clinical trial of Aurora kinase peptide vaccination for the treatment of refractory or relapsed acute myeloid leukemia.2017
- Author(s)
  Fujiwara H, Tanimoto K, Ochi T, Kuzushima K, Yasukawa M.
- Organizer
  43th Annual Meeting of the European Group for Blood and Marrow Transplantation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] Phase I/II clinical trial of Aurora kinase peptide vaccination for the treatment of refractory or relapsed acute myeloid leukemia.2017
- Author(s)
  Fujiwara H, Tanimoto K, Ochi T, Kuzushima K, Yasukawa M.
- Organizer
  43th Annual Meeting of the European Group for Blood and Marrow Transplantation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Strategically Comprehensive Immunotherapy Employing Modified Antibody Targeting NY-ESO-1 for Multiple Myeloma2017
- Author(s)
  丸田雅樹，越智俊元，谷本一史，東太地，藤原弘，安川正貴
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09957
[Presentation] 治療抵抗性急性骨髄性白血病に対するAurora Kinase Aペプチドワクチン療法第I/II2016
- Author(s)
  谷本一史、藤原弘、越智俊元、東太地、竹内一人、葛島清隆、安川正貴.
- Organizer
  第8回　血液疾患免疫療法学会学術集会
- Place of Presentation
  北海道札幌市　北海道大学医学部学友会館「フラテ」
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 白血病に対する遺伝子免疫細胞療法の新展開2016
- Author(s)
  藤原　弘
- Organizer
  第77回　日本血液学会学術集会
- Place of Presentation
  石川県金沢市　ホテル日航金沢
- Year and Date
  2016-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] WT1ペプチド-HLA-A24複合体を認識するヒト抗体の単離とそれを用いたCAR治療法の開発2016
- Author(s)
  赤堀泰、米山元裕、池田裕明、宮原慶裕、織戸由貴、天石泰典、岡本幸子、峰野純一、竹迫一任、珠玖洋、安川正貴、藤原弘
- Organizer
  第20回　日本がん免疫学会総会
- Place of Presentation
  大阪府大阪市　大阪国際交流センター
- Year and Date
  2016-07-27
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 造血器腫瘍に対するWT1特異的T細胞受容体遺伝子導入Tリンパ球輸注療法2016
- Author(s)
  俵功、藤原弘、村田誠、赤塚美樹、西田徹也、寺倉精太郎、恵美宣彦、桝屋正浩、池田裕明、片山直之、安川正貴、影山慎一、珠玖洋
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市・パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] がん免疫療法の可能性2016
- Author(s)
  藤原　弘
- Organizer
  「九州がんプロ養成基盤推進プラン」第2回がんプロ講演会
- Place of Presentation
  佐賀県佐賀市　佐賀大学医学部
- Year and Date
  2016-01-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 治療抵抗性急性骨髄性白血病に対するAurora Kinase ペプチドワクチン療法2016
- Author(s)
  谷本一史、藤原弘、越智俊元、東太地、竹内一人、葛島清隆、安川正貴.
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市・パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Dasatinib combined with IFN-a induces a major molecular response in a patient with T315I-CML.2016
- Author(s)
  東太地、谷本一史、朝井洋晶、竹内一人、山之内純、藤原弘、羽藤高明、安川正貴.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Antileukemia adoptive immunotherapy using gene-modified T cells to2016
- Author(s)
  Fujiwara H
- Organizer
  第20回日本がん免疫学総会（シンポジウム）
- Place of Presentation
  大阪府大阪市　大阪国際交流センター
- Year and Date
  2016-07-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Phase 1 Clinical Trial of Adoptive Immunotherapy for Acute Myelogenous Leukemia and Myelodysplastic Syndrome, Using Gene-Modified Autologous Lymphocytes Expressing WT1-Specific T-Cell Receptor2016
- Author(s)
  Kazushi Tanimoto, Hiroshi Fujiwara, Isao Tawara, Masahiro Masuya, Shinichi Kageyama, Tetsuya Nishida, Makoto Murata, Seitaro Terakura, Yoshiki Akatsuka, Hiroaki Ikeda, Yoshihiro Miyahara, Ikuei Nukaya, Kazutoh Takesako, Nobuhiko Emi, Naoyuki Katayama, Hiroshi Shiku, Masaki Yasukawa
- Organizer
  American Society of Hematology Annual Meeting 2016
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04858
[Presentation] がんに対する細胞免疫療法の新展開2016
- Author(s)
  藤原　弘
- Organizer
  第66回日本輸血・細胞治療学会東海支部例会
- Place of Presentation
  愛知県名古屋市名古屋市立大学
- Year and Date
  2016-02-06
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Wilms Tumor 1 specific T-cell receptor gene-modified autologous lymphocytes displayed a transient clinical response in a patient with acute myeloid leukemia.2016
- Author(s)
  Hiroshi Fujiwara, Kazushi Tanimoto, Nicholas Casey, Taichi Azuma, Kazuto Takeuchi, Shinichi Kageyama, Hiroaki Ikeda, Sachiko Okamoto, Junichi Mineno, Hiroyoshi Nishikawa, Hiroshi Shiku, Masaki Yasukawa
- Organizer
  42nd Annual Meeting of the European Society for Blood and Marrow Transplantation
- Place of Presentation
  Valencia, Spain
- Year and Date
  2016-04-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Optimization of antitumor TCR by exploiting TCR chain centricity for successful TCR gene therapy.2016
- Author(s)
  越智俊元、Bulter M、藤原弘、安川正貴、平野直人
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Clinical study of novel adoptive immunotherapy using gene-modified2016
- Author(s)
  Fujiwara H
- Organizer
  第22回　日本遺伝子細胞治療学会学術集会（シンポジウム）
- Place of Presentation
  東京都港区　虎の門ヒルズ
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] AML-MRCに対しWT1-siTCR-T細胞療法を施行した一例2016
- Author(s)
  谷本一史、藤原　弘、東　太地、影山慎一、池田裕明、糠谷育衛、岡本幸子、峰野純一、珠玖　洋、安川正貴
- Organizer
  第38回　日本造血細胞移植学会総会
- Place of Presentation
  愛知県名古屋市　国際会議場
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Adoptive immunotherapy using WT1-specific T-cell receptor gene-modified lymphocytes for the treatment of patients with acute myelogenous leukemia and myelodysplastic syndrome.2016
- Author(s)
  Fujiwara H, Tanimoto K, Tawara I, Masuya M, Miyahara Y, Nishida T, Murata M, Terakura S, Akatsuka Y, Ikeda H, Kageyama S, Nukaya I, Takesako K, Nobuyuki Emi N, Katayama N, Shiku H, Yasukawa M.
- Organizer
  The 7th JSH International Symposium
- Place of Presentation
  Awaji, Hyogo, Japan, Westin Hotel Awaji
- Year and Date
  2016-05-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Phase 1 Clinical Trial of Adoptive Immunotherapy for Acute Myelogenous Leukemia2016
- Author(s)
  Tanimoto K, Fujiwara H, Tawara I, Masuya M, Kageyama S, Nishida T, Murata
- Organizer
  The 58th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] 治療抵抗性急性骨髄性白血病及び予後不良骨髄異形成症候群に対するWT1特異的TCR遺伝子導入T細胞療法・第I相臨床試験.2016
- Author(s)
  藤原　弘
- Organizer
  第8回　血液疾患免疫療法学会学術集会（シンポジウム）
- Place of Presentation
  北海道札幌市　北海道大学医学部学友会館「フラテ」
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Clinical application of anti-CML immunity in the era of TKI therapy.2016
- Author(s)
  Fujiwara H
- Organizer
  Hematology Winter Symposium, Combined meeting of Hematology Society of
- Place of Presentation
  Kaohsiung, Taiwan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Aurora-A kinase vaccine therapy in myeloid leukemia patients.2016
- Author(s)
  Tanimoto K, Fujiwara H, Ochi T, Yamanouchi J, Azuma T, Hato T, Yasukawa M.
- Organizer
  第20回　日本がん免疫学会総会
- Place of Presentation
  大阪府大阪市　大阪国際交流センター
- Year and Date
  2016-07-27
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Development of antileukemia adoptive immunotherapy using gene-2015
- Author(s)
  Hiroshi Fujiwara
- Organizer
  第21回　日本遺伝子治療学会学術集会　Symposium III
- Place of Presentation
  大阪府大阪市　国際会議場
- Year and Date
  2015-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Immunotherapy with Chimeric Antigen Receptor Targeting Intracellular WT1 Gene Product Complexed with HLA-a*24:02 Molecule2015
- Author(s)
  Hiroaki Ikeda, Yasushi Akahori, Motohiro Yoneyama, Yuki Orito, Yoshihiro Miyahara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Kazutoh Takesako, Hiroshi Fujiwara, Masaki Yasukawa, Hiroshi Shiku
- Organizer
  American Society of Hematology 2015 Annual Meeting
- Place of Presentation
  米国　オーランド
- Year and Date
  2015-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04858
[Presentation] Targeting Aurora Kinase with a Superior T-Cell Receptor Gene-Transfer Vector2015
- Author(s)
  Nicholas Casey, Hiroshi Fujiwara, Kazushi Tanimoto, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Masaki Yasukawa
- Organizer
  57th Annual Meeting of American Society of Hematology
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Targeting Aurora Kinase A utilizing and improved TCR gene-transfer vector.2015
- Author(s)
  Nicholas Casey, Hiroshi Fujiwara, Sachiko Okamoto, Junichi Mineno, Kiyotaka
- Organizer
  第19回日本がん免疫学会総会
- Place of Presentation
  東京都文京区　東京大学　伊藤国際学術研究センター
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Adoptive Transfer of WT1-Specific TCR Gene-Transduced Lymphocytes in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia2015
- Author(s)
  Isao Tawara, Masahiro Masuya, Shinichi Kageyama, Tetsuya Nishida, Seitaro Terakura, Makoto Murata, Hiroshi Fujiwara, Yoshiki Akatsuka, Hiroaki Ikeda, Yoshihiro Miyahara, Daisuke Tomura, Ikuei Nukaya, Kazutoh Takesako, Nobuhiko Emi, Masaki Yasukawa, Naoyuki Katayama, Hiroshi Shiku
- Organizer
  57th Annual Meeting of American Society of Hematology
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Immunotherapy with Chimeric Antigen Receptor Targeting Intracellular WT1 Gene Product Complexed with HLA-A*24:02 Molecule2015
- Author(s)
  Hiroaki Ikeda, Yasushi Akahori, Motohiro Yoneyama, Yuki Orito, Yoshihiro Miyahara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Kazutoh Takesako, Hiroshi Fujiwara, Masaki Yasukawa, Hiroshi Shiku
- Organizer
  57th Annual Meeting of American Society of Hematology
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Lentivirally gene-modified T cells expressing chimeric CD16-CD3zeta receptors and mogamulizumab for the treatment of adult T cell leukemia2015
- Author(s)
  Hiroki Tanaka, Hiroshi Fujiwara, Kazushi Tanimoto, Fumihiro Ochi, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Masaki Yasukawa
- Organizer
  第19回日本がん免疫学会総会
- Place of Presentation
  東京都文京区　東京大学　伊藤国際学術研究センター
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Targeting Aurora Kinase with a Superior T-Cell Receptor Gene-Transfer Vector2015
- Author(s)
  Nicholas Casey, Hiroshi Fujiwara, Kazushi Tanimoto, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Masaki Yasukawa
- Organizer
  American Society of Hematology 2015 Annual Meeting
- Place of Presentation
  米国　オーランド
- Year and Date
  2015-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04858
[Presentation] Multicenter Phase II Study of Lenalidomide in Patients with Relapsed Adult T-Cell Leukemia-Lymphoma2015
- Author(s)
  Hiroshi Fujiwara, Takashi Ishida, Kisato Nosaka, Naoya Taira, Yasunobu Abe, Yoshitaka Imaizumi, Yukiyoshi Moriuchi, Tatsuro Jo, Kenichi Ishizawa, Kensei Tobinai, Kunihiro Tsukasaki, Shigeki Ito, Makoto Yoshimitsu, Maki Otsuka, Michinori Ogura, Shuichi Midorikawa, Wanda Ruiz, Tomoko Ohtsu
- Organizer
  57th Annual Meeting of American Society of Hematology
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] WT1-siTCR細胞療法を施行したAML/MTDの一例2015
- Author(s)
  谷本一史、藤原　弘、Nicholas Casey、東　太地、影山慎一、池田裕明、糠谷育衛、
- Organizer
  第7回　血液疾患免疫療法研究会学術集会
- Place of Presentation
  東京都文京区　東京大学　伊藤国際学術研究センター
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Souped-up gene-modified T cells expressing chimeric CD16-CD3zeta receptors against mogamulizumab-opsonized ATL cells.2015
- Author(s)
  Hiroki Tanaka, Hiroshi Fujiwara, Kazushi Tanimoto, Fumihiro Ochi, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Masaki Yasukawa
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市　国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Gene-modified T cells expressing souped-up chimeric CD16-CD3zeta receptors with mogamulizumab for ATL2015
- Author(s)
  Hiroki Tanaka, Hiroshi Fujiwara, Kazushi Tanimoto, Fumihiro Ochi, Masaki Yasukawa
- Organizer
  第77回　日本血液学会学術集会
- Place of Presentation
  石川県金沢市　ホテル日航金沢
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Adoptive Transfer of WT1-Specific TCR Gene-Transduced Lymphocytes in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia2015
- Author(s)
  Isao Tawara, Masahiro Masuya, Shinichi Kageyama, Tetsuya Nishida, Seitaro Terakura, Makoto Murata, Hiroshi Fujiwara, Yoshiki Akatsuka, Hiroaki Ikeda, Yoshihiro Miyahara, Daisuke Tomura, Ikuei Nukaya, Kazutoh Takesako, Nobuhiko Emi, Masaki Yasukawa, Naoyuki Katayama, Hiroshi Shiku
- Organizer
  American Society of Hematology 2015 Annual Meeting
- Place of Presentation
  米国　オーランド
- Year and Date
  2015-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04858
[Presentation] A new dimension of gene-modified T cell-based adoptive immunotherapy for the treatment of leukemia2015
- Author(s)
  Hiroshi Fujiwara
- Organizer
  第74回　日本癌学会学術総会　JCA-AACR Joint Symposia
- Place of Presentation
  愛知県名古屋市　国際会議場
- Year and Date
  2015-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] A phase I clinical trial of adoptive transfer of WT1 redirected T cells for refractory AML and MDS2015
- Author(s)
  Hiroshi Fujiwara, Isao Tawara, Kazushi Tanimoto, Tetsuya Nishida, Makoto Murata, Seitaro Terakura, Ikuei Nukaya, Yoshiki Akatsuka, Masataka Okamoto, Masahiro Masuya, Hiroaki Ikeda, Sinichi Kageyama, Nobuhiko Emi, Naoyuki Katayama, Masaki Yasukawa, Hiroshi Shiku
- Organizer
  第77回　日本血液学会学術集会
- Place of Presentation
  石川県金沢市　ホテル日航金沢
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K09506
[Presentation] Activation Status of Integrin αIIbβ3 in Essential Thrombocythemia with Calreticulin Mutation2014
- Author(s)
  Jun Yamanouchi , Takaaki Hato, Etsuko Matsubara, Taichi Azuma, Hideyuki Nakanishi, Hiroshi Fujiwara, Yoshihiro Yakushijin, and Masaki Yasukawa
- Organizer
  56th ASH Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24390245
[Presentation] Concomitant Administration of Gene-Modified T Cells Expressing a Chimeric CD16-CD3ζ Receptor with Mogamulizmab Synergistically Suppresses Adult T Cell Leukemia Cells in Vivo2014
- Author(s)
  Kazushi Tanimoto , Hiroshi Fujiwara, Hiroki Tanaka, Fumihiro Ochi , Hiroaki Asai, Sachiko Okamoto, JunichiMineno , Kiyotaka Kuzushima, Hiroshi Shiku, John Barrett, and Masaki Yasukawa
- Organizer
  56th ASH Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-24390245
[Presentation] TCR遺伝子導入T細胞を用いる養子免疫療法・最近の知見2014
- Author(s)
  藤原　弘*
- Organizer
  第6回　血液疾患免疫療法研究会　シンポジウム
- Place of Presentation
  京都市
- Year and Date
  2014-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Human telomerase reverse transcriptase-specific T-cell receptor gene transfer redirects T cells to display an effective antitumour reactivity against adult T-cell leukemia.2013
- Author(s)
  Fujiwara H et al.
- Organizer
  39th Annual Meeting of the European Group for Blood and Marrow Transplantation
- Place of Presentation
  London, UK
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] TCR遺伝子改変T細胞を用いて白血病性幹細胞を狙い撃つ。2013
- Author(s)
  藤原　弘
- Organizer
  第11回神奈川ヘマトロジーカンファレンス
- Place of Presentation
  神奈川県　横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective antileukemia reactivity.2012
- Author(s)
  Fujiwara H
- Organizer
  The 10th Advanced Hematology Seminar.
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] WT1を治療標的抗原とする白血病幹細胞制御を目指した細胞免疫療法の可能性の検討。2012
- Author(s)
  藤原　弘　他.
- Organizer
  第4回造血器腫瘍免疫療法研究会学術集会
- Place of Presentation
  石川県　金沢市
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Multifactorial help by WT1-specific TCR gene transduced CD4+ T cells in T cell-based immunotherapy.2012
- Author(s)
  Fujiwara H et al.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] 抗白血病性T細胞ネットワークを輸注する次世代型遺伝子免疫療法の開発研究2012
- Author(s)
  藤原弘, 他
- Organizer
  第34回日本造血細胞移植学会総会(ワークショップ)
- Place of Presentation
  大阪市
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Adoptive T-cell immunotherapy for leukemia using T-cell receptor gene transfer2012
- Author(s)
  Hiroshi Fujiwara
- Organizer
  The 27^<th> Nagoya International Cancer Treatment Symposium
- Place of Presentation
  Nagoya, Japan(招聘講演)
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] 白血病に対する細胞免疫療法の考え方-ペプチドワクチンから細胞療法へ-2012
- Author(s)
  藤原　弘
- Organizer
  第28回セルセラピーセミナー
- Place of Presentation
  群馬県　前橋市
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] 血液がんに対する免疫療法の考え方-ワクチンから細胞療法へ-2012
- Author(s)
  藤原　弘
- Organizer
  第5回大隅血液セミナー
- Place of Presentation
  鹿児島県　鹿屋市
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Human Telomerase Reverse Transcriptase-specific T-Cell Receptor Gene Transfer Redirects T Cells to Display an Effective Antitumor Reactivity Against Adult T-Cell Leukemia.2012
- Author(s)
  Fujiwara H et al.
- Organizer
  The 54th Annual Meeting of the American Society of Hematology.
- Place of Presentation
  Atlanta, GA
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Detailed analysis of helper functions mediated by genetically engineered CD4+ T cells to express HLA-A24 and WT1-specific T-cell receptor in redirected T cell-based adoptive immunotherapy against human leukemia.2012
- Author(s)
  Fujiwara H et al.
- Organizer
  The 6th International Conference on WT1 in Human Neoplasia.
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Active Application of Genetically Redirected CD4+ T cells Using Tumor Antigen-specific TCR Gene Transfer in Redirected T cell-based Antileukemia Adoptive Immunotherapy.2012
- Author(s)
  Fujiwara H et al.
- Organizer
  The 3rd Workshop of Synthetic Immunology.
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Human Telomerase Reverse Transcriptase-specific T-Cell Receptor Gene Transfer Redirects T Cells to Display an Effective Antitumor Reactivity Against Adult T-Cell Leukemia2012
- Author(s)
  Fujiwara H, Yasukawa M, et al.
- Organizer
  54th Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, USA
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-24390245
[Presentation] Active application of leukemia antigen-specific T-cell receptor introduced CD4+ T cells immunocell therapy.2012
- Author(s)
  Fujiwara H et al.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  北海道　札幌市
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Engineered T-lymphocytes using a novel anti-leukemia antigen, aurora-Akinase-specific T-cell receptor gene transfer successfully displayed anti-leukemia reactivity2011
- Author(s)
  Hiroshi Fujiwara, et al
- Organizer
  37^<th> Annual congress of the European Group for Blood and Marrow Transpalnt-ation
- Place of Presentation
  Paris, France(Van Bekkum Award受賞講演)
- Year and Date
  2011-04-03
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] WT1特異的TCR遺伝子導入CD4リンパ球の機能解析とAurora kinase Aペプチドワクチン臨床試験の経過報告2011
- Author(s)
  越智俊元、藤原弘、安川正貴
- Organizer
  平成23年度がん研究開発費・佐藤班班会議
- Place of Presentation
  札幌市
- Year and Date
  2011-07-26
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] 白血病性幹細胞を標的とした細胞免疫療法の開発研究2011
- Author(s)
  藤原弘
- Organizer
  第7回HLA不適合移植研究会
- Place of Presentation
  岡山市(招聘講演)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] 腫瘍抗原特異的T細胞受容体遺伝子を用いた白血病に対する遺伝子免疫療法の開発研究(続報)-TCR遺伝子治療の抱える問題点の克服に向けた試み-2011
- Author(s)
  藤原弘, 他
- Organizer
  第33回日本造血細胞移植学会総会
- Place of Presentation
  松山市
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Anti-leukemia functionality mediated by redirected T cells using LAA-specific TCR ; aiming at the persistent control of leukemia stem cells2011
- Author(s)
  Hiroshi Fujiwara
- Organizer
  Invited lecture at National Heart, Lung and Blood Institute/NIH(招聘講演)
- Place of Presentation
  Bethesda, MA, USA
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Dual engineering of human CD8^+ T-cells with WT1-specific TCR gene and chemokine receptor gene transfer confers functionally strengthened anti-cancer reactivity2011
- Author(s)
  Hiroshi Fujiwara, et al
- Organizer
  5^<th> International Conference on WT1 in Human Neoplasia
- Place of Presentation
  Turin, Italy(招聘講演)
- Year and Date
  2011-04-15
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Detailed assessment of anti-leukemia effect and safety of redirected T cells using WT1-siTCR vector2011
- Author(s)
  Hiroshi Fujiwara et al
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Engineered T-lymphocytes using a novel anti-leukemia antigen, aurora-Akinase-specific T-cell receptor gene transfer successfully displayed anti-leukemia reactivity2011
- Author(s)
  Hiroshi Fujiwara et al
- Organizer
  37^<th> Annual Congress of European Group for Blood and Barrow Transplantation(EBMT総会)(Van Bekkum Award受賞講演)
- Place of Presentation
  Paris France
- Year and Date
  2011-04-03
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] がん抗原特異的T細胞受容体遺伝子を用いた遺伝子免疫療法の開発研究2011
- Author(s)
  藤原弘, 他
- Organizer
  がん研究助成金佐藤班平成21年度第2回班会議
- Place of Presentation
  札幌市
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Dual engineering of human CD8^+ T-cells with WT1-specific TCR gene and chemokine receptor gene transfer confers functionally strengthened anti-cancer reactivity2011
- Author(s)
  Hiroshi Fujiwara et al
- Organizer
  5^<th> International Conference on WT1 in Human Neoplasia(招聘講演)
- Place of Presentation
  Turin, Italy
- Year and Date
  2011-04-15
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Anti-leukemia functionality mediated by redirected T cells using LAA-specific TCR ; aiming at the persistent control of leukemia stem cells2011
- Author(s)
  Hiroshi Fujiwara
- Organizer
  Lecture at National Heart, Lung and Blood Institute/National Institute of Health
- Place of Presentation
  Bethesda, MD, USA(招聘講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Our current attempts to develop a novel gene-immunotherapy agains thuman leukemia.2010
- Author(s)
  Hiroshi Fujiwara.
- Organizer
  Lecture at National Heart, Lung and Blood Institute/National Institute of Health
- Place of Presentation
  Bethesda, USA(招聘講演)
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Development of gene-immunotherapy against human leukemia with engineered T-cells using WT-1-specific T-cell receptor gene transfer2010
- Author(s)
  Hiroshi Fujiwara et al
- Organizer
  36^<th> EBMT総会
- Place of Presentation
  Vienna Austria
- Year and Date
  2010-03-23
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Gene-engineered T-cell therapy against malignancies2010
- Author(s)
  Hiroshi Fujiwara
- Organizer
  第72回血液学会学術集会・シンポジウム1 Cancer immunotherapy : Current status and future prospects(招聘講演)
- Place of Presentation
  横浜市
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Gene-engineered T-cell therapy against malignancies.2010
- Author(s)
  Hiroshi Fujiwara
- Organizer
  第72回血液学会学術集会・シンポジウム1 Cancer immunotherapy : Current status and future prospects
- Place of Presentation
  横浜市(招聘講演)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] 移植片対白血病効果に関する再考察:同種免疫応答は必要か?2010
- Author(s)
  藤原弘
- Organizer
  Meet the Expert
- Place of Presentation
  岡山市(招聘講演)
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Genetically engineered T-cell therapy for cancer.2010
- Author(s)
  Hiroshi Fujiwara, et al.
- Organizer
  第16回日本遺伝子治療学会(JSGT)年次学術集会・Joint Symposium with the Society of Immunotherapy for Hematological Malignancies Cancer Immunotherapy & Gene Therapy
- Place of Presentation
  宇都宮市
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Co-engineered T cells using chemokine-receptor and tumor-specific TCR genes for adoptive therapy2010
- Author(s)
  Hiroshi Fujiwara, et al.
- Organizer
  第72回血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Our current attempts to develop a novel gene-immunotherapy against human leukemia2010
- Author(s)
  Hiroshi Fujiwara
- Organizer
  Invited lecture at National Heart, Lung and Blood Institute/NIH(招聘講演)
- Place of Presentation
  Bethesda, MA, USA
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Genetically engineered T-cell therapy for cancer2010
- Author(s)
  Hiroshi Fujiwara
- Organizer
  第16回日本遺伝子治療学会(JSGT)年次学術集会・Joint Symposium with the Society of Immunotherapy for Hematological Malignancies Cancer Immunotherapy & Gene Therapy(招聘講演)
- Place of Presentation
  宇都宮市
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Engineered T cells using both chemokine-receptor gene and tumor-specific TCR gene transfer for adoptive therapy.2010
- Author(s)
  Hiroshi Fujiwara, et al.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] WT1を標的とした遺伝子免疫療法の開発研究up-dated2010
- Author(s)
  藤原弘, 他
- Organizer
  第12回WT1癌抗原ペプチド癌免疫療法研究会
- Place of Presentation
  大阪市
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] TCR遺伝子治療開発研究の現状と抗腫瘍免疫の可視化2010
- Author(s)
  藤原弘, 他
- Organizer
  平成22年度がん研究開発費佐藤班班会議
- Place of Presentation
  小樽市
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] WT1-targeting immuno-gene therapy for human leukemia by using WT1-specific T cell receptor gene transfer2009
- Author(s)
  Hiroshi Fujiwara, et al
- Organizer
  4^<th> International Congress on WT1 in Human Neoplasia
- Place of Presentation
  Osaka, Japan
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Development of cancer gene-immunotherapy using Aurora-A kinase-specific T-cell receptor genes2009
- Author(s)
  Hiroshi Fujiwara, et al
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] Aurora A kinase : a novel target of immunotherapy against human leukemia2009
- Author(s)
  H. Fujiwara, T. Ochi, et al.
- Organizer
  35th Annual Meeting of the European Group for Blood and Marrow Transplantation, Presidential Symposium
- Place of Presentation
  Goteborg, Sweden
- Year and Date
  2009-03-31
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Development of immune-gene therapy using Aurora-A kinase specific T-cell receptor gene2009
- Author(s)
  Hiroshi Fujiwara et al
- Organizer
  第68回日本癌学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] 抗ATL腫瘍免疫抗原としてのHBZの検討2009
- Author(s)
  小川泰司、藤原弘、末盛浩一郎、東太地、松岡雅雄、松元正、安川正貴
- Organizer
  第31回日本造血細胞移植学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-02-05
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora A kinase : a novel target of immunotherapy against human leukemia2009
- Author(s)
  Hiroshi Fujiwara, Toshiki Ochi, Taichi Azuma, Kiyotaka Kuzushima, Masaki Yasukawa
- Organizer
  35^<th> Annual Meeting of the European Group for Blood and Marrow Transplantation
- Place of Presentation
  Goeteborg, Sweden
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Development of immune-gene therapy using Aurora-Akinase-specific T-cell receptor gene2009
- Author(s)
  Hiroshi Fujiwara, et al
- Organizer
  第68回日本癌学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21591245
[Presentation] 抗ATL腫瘍免疫抗原としてのHBZの検討2009
- Author(s)
  小川泰司, 藤原弘, 他
- Organizer
  第31回日本造血細胞移植学会総会WS-1-2-3
- Place of Presentation
  札幌市
- Year and Date
  2009-02-05
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A Kinaseを標的とした白血病に対する免疫療法の開発2008
- Author(s)
  越智俊元, 藤原弘, 他
- Organizer
  第12回基盤的癌免疫療法研究会
- Place of Presentation
  大宮市
- Year and Date
  2008-07-02
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A kinase : A novel target of cellular immunotherapy for human leukemia.2008
- Author(s)
  T. Ochi, H. Fujiwara, et al.
- Organizer
  50th Annual Meeting of American Society of Hematology.
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] 細胞傷害活性を持った新しいCD3+CD8+腫瘍性T細胞株(SF-1)の樹立2008
- Author(s)
  藤原弘, 末盛浩一郎, 他
- Organizer
  第70回日本血液学会絵会
- Place of Presentation
  京都市
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A Kinaseを標的とした白血病に対する免疫療法の開発2008
- Author(s)
  越智俊元, 藤原弘, 他
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Perforin/Granzyme系を介した細胞傷害活性を持つCD3+CD8+T細胞リンパ腫細胞株の樹立2008
- Author(s)
  藤原弘, 末盛浩一郎, 他
- Organizer
  第2回基盤的癌免疫療法研究会
- Place of Presentation
  大宮市
- Year and Date
  2008-07-02
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] 腫瘍関連抗原CML66の臨床的有用性2008
- Author(s)
  末盛浩一郎, 藤原弘, 他
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都市
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] 細胞傷害活性を持った新しいCD3+CD8+腫瘍性T 細胞株(SF-1)の樹立2008
- Author(s)
  藤原弘、末盛浩一郎、東太地、新家敏之、安川正貴
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] パーフォリン/グランザイムBを介した細胞傷害活性を示す新たなCD8陽性T細胞株の樹立2008
- Author(s)
  末盛浩一郎, 藤原弘, 他
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] 腫瘍関連抗原CML66 の臨床的有用性2008
- Author(s)
  末盛浩一郎、藤原弘、越智俊元、東太地、成見弘、安川正貴
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A kinase : A novel target of cellular immunotherapy for human leukemia2008
- Author(s)
  Toshiki Ochi, Hiroshi Fujiwara, Koichiro Suemori, Taichi Azuma, Kiyotaka Kuzuhima, Masaki Yasukawa
- Organizer
  50^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco, California, USA.
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] HBZ特異的細胞傷害性T細胞クローンの樹立と機能解析2008
- Author(s)
  安川正貴, 藤原弘, 他
- Organizer
  第56回日本ウイルス学会総会
- Place of Presentation
  岡山市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] HBZ特異的細胞傷害性T細胞クローンの樹立と機能解析2008
- Author(s)
  安川正貴、末盛浩一郎、藤原弘、松岡雅雄
- Organizer
  第56回日本ウイルス学会総会
- Place of Presentation
  岡山
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A Kinaseを標的とした白血病に対する免疫療法の開発2008
- Author(s)
  越智俊元, 藤原弘, 他
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都市
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] パーフォリン/グランザイムB を介した細胞傷害活性を示す新たなCD8 陽性T 細胞株の樹立。2007
- Author(s)
  末盛浩一郎、藤原弘、越智俊元、東太地、安川正貴
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Cytotoxic T-lymphocyte harnessing CML66 can kill human myeloid leukemia cells, in vitro.2007
- Author(s)
  Koichiro Suemori, Hiroshi Fujiwara, Toshiki Ochi, Masaki Yasukawa
- Organizer
  49^<th> Annual meeting of American Society of Hematology 2007
- Place of Presentation
  Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A特異的CTLの誘導と機能解析2007
- Author(s)
  越智俊元、藤原弘, 他
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] 成人T細胞白血病リンパ腫におけるPD-1/PD-L1経路の関与の検討2007
- Author(s)
  吉満誠、小迫知弘、藤原弘、政元いずみ、鈴木伸介、松下格司、魚住公治、鄭忠和、有馬直道
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Identification of epitopes derived from Aurora-A kinase which induce leukemia-specific CTL2007
- Author(s)
  越智俊元、藤原弘, 他
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] CTL exhaustion in persistent HTLV-I infection and ATLL is restored through PD-1/PD-L1 pathway2007
- Author(s)
  Kozako T, Fujiwara H, et. al.
- Organizer
  49^<TH> Annual meeting and exposition American Society of Hematology
- Place of Presentation
  Atlanta,U.S.A.
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] 新規骨髄性自血病関連抗原CML66に対する細胞傷害性Tリンパ球の誘導2007
- Author(s)
  末盛浩一郎、藤原弘, 他
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] CTL exhaustion in persistent HTLV-1 infection and ATLL is restored through PD-1/PD-L1 pathway.2007
- Author(s)
  Tomohiro Kozako, Makoto Yoshimitsu, Hiroshi Fujiwara, Izumi Masamoto, Sawako Horai, Masaki Akimoto, Yukio Suruga, Hideaki Kawada, Heiichiro Hamada, Noriko Aoki, Sinsuke Suzuki, Kakushi Matsushita, Kimiharu Uozumi, Chuwa Tei, Naomichi Arima
- Organizer
  49^<th>Annual meeting of American Society of Hematology 2007
- Place of Presentation
  Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Induction and functional analysis of CML66-specific cytotoxic T lymphocytes2007
- Author(s)
  末盛浩一郎、藤原弘, 他
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A kinase: A novel target for the immunotherapy against human leukemia2007
- Author(s)
  Ochi T, Fujiwara H, et. al.
- Organizer
  49^<TH> Annual meeting and exposition American Society of Hematology
- Place of Presentation
  Atlanta,U.S.A.
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Aurora-A kinase : A novel target for the immunotherapy against human leukemias.2007
- Author(s)
  Toshiki Ochi, Hiroshi Fujiwara, Koichiro Suemori, Taichi Azuma, Kiyotaka Kuzushima, Masaki Yasukawa
- Organizer
  49^<th> Annual meeting of American Society of Hematology 2007
- Place of Presentation
  Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] HTLV-I陽性donor由来のHTLV-I Tax特異的CTLは移植後早期の移植片対ATL効果に必ずしも寄与しない2007
- Author(s)
  藤原弘, 他
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] HTLV-1陽性donor 由来のHTLV-1Tax 特異的CTLは、移植後早期の移植片対ATL効果に必ずしも寄与しない2007
- Author(s)
  藤原弘、尾崎厚夫、吉満誠、小迫知弘、濱田平一郎、政元いずみ、安川正貴、鄭忠和
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] Cytotoxic T-lymphocyte harnessing CML66 can kill human myeloid leukemia cells,in Vitro2007
- Author(s)
  Suemori K, Fujiwara H, et. al.
- Organizer
  49^<TH> Annual meeting and exposition American Society of Hematology
- Place of Presentation
  Atlanta,U.S.A.
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19591121
[Presentation] キメラ型CD16遺伝子改変T細胞は抗腫瘍性ADCC活性におけるNK細胞の問題点を解決できる可能性がある。
- Author(s)
  藤原　弘　他
- Organizer
  第36回日本造血細胞移植学会
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] High-quality TCR-gene modified T cells using siTCR lentiviral vector in combination with anti-CD3/CH296 stimulation.
- Author(s)
  岡本幸子、池田裕明、藤原　弘*、安川正貴、珠玖　洋、峰野純一
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Generation of HLA class I-restricted TCR-gene modified CD4+ T-cell subtype for antileukemia adoptive immunotherapy.
- Author(s)
  朝井洋晶、藤原　弘*、越智史博、越智俊元、岡本幸子、峰野純一、葛島清隆、珠玖　洋、安川正貴
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] ポテリジオを併用したATLに対する新たな細胞免疫療法の可能性.
- Author(s)
  田中寛希、藤原　弘*、越智史博、谷本一史、朝井洋晶、那波明宏、安川正貴
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Gene-modified CD4+ T cells using HLA class I-restricted and WT1-specific T-cell receptor gene transfer successfully enhance the antileukemia efficacy of redirected T cell-based adoptive immunotherapy
- Author(s)
  Hiroshi Fujiwara.
- Organizer
  The 4th JSH (Japanese Society of Hematology) International Symposium
- Place of Presentation
  Matsuyama, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Concomitant administration of gene-modified T cells expressing a chimeric CD16-CD3zeta receptor with Mogamulizmab synergistically suppresses adult T cell leukemia cells in vivo.
- Author(s)
  Tanimoto K, Fujiwara H*, Tanaka H, Ochi F, Asai H, Okamoto S, Mineno J, Kuzushima K, Shiku H, Barrett AJ, Yasukawa M.
- Organizer
  56th American Society of Hematology, Annual meeting and Exposition
- Place of Presentation
  San Francisco, CA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Activation Status of Integrin αIIbβ3 in Essential Thrombocythemia with Calreticulin Mutation.
- Author(s)
  Yamanouchi J, Hato T, Matsubara E, Azuma T, Nakanishi H, Fujiwara H*, Yakushijin Y, Yasukawa M.
- Organizer
  56th American Society of Hematology, Annual meeting and Exposition
- Place of Presentation
  San Francisco, CA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Gene-modified human α/β-T cells expressing a chimeric CD16-CD3ζ receptor as adoptively transferable effector cells for anticancer monoclonal antibody therapy
- Author(s)
  Hiroshi Fujiwara
- Organizer
  40th Annual Meeting of the European Society for Blood and Marrow Transplantation.
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Co-Administration of Gene-Modified CD4+ T Cells Targeting HLA Class I-Restricted WT1 Epitope Diversely Enhances The Antitumor Effect Mediated By Redirected T-Cell Based Adoptive Immunotherapy Against Human Leukemia.
- Author(s)
  Hiroshi Fujiwara et al.
- Organizer
  55th American Society of Hematology, Annual meeting and Exposition.
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Targeting Aurora Kinase A with an enhanced T-cell receptor gene-transfer vector.
- Author(s)
  Hiroshi Fujiwara*, Nicholas Casey, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Shiku Hiroshi, Masaki Yasukawa
- Organizer
  第76回　日本血液学会学術集会（English Session）
- Place of Presentation
  大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Redirected T cell-based antileukemia adoptive immunotherapy using tumor-specific TCR gene transfer.
- Author(s)
  Hiroshi Fujiwara
- Organizer
  第75回日本血液学会学術集会 Symposium4. (English Session)
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] hTERTを治療標的抗原とするATLに対する新規細胞免疫療法の開発研究
- Author(s)
  藤原　弘
- Organizer
  第2回　ATLシンポジウム／第6回HTLV-1研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] 遺伝子改変T細胞による血液腫瘍に対する養子免疫療法
- Author(s)
  藤原　弘*
- Organizer
  第76回日本血液学会学術集会　教育講演EL-56
- Place of Presentation
  大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] がんに対するT細胞受容体（TCR）遺伝子導入T細胞を用いる細胞免疫療法
- Author(s)
  藤原　弘*
- Organizer
  第18回　日本がん免疫学会総会、シンポジウム2
- Place of Presentation
  松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Human telomerase reverse transcriptase‒specific T-cell receptor gene transfer redirects T cells to display an effective antitumor reactivity against adult T-cell leukemia.
- Author(s)
  Hiroshi Fujiwara
- Organizer
  39th Annual Meeting of the European Group for Blood and Marrow Transplantation.
- Place of Presentation
  London, UK
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] HLA class-I restricted tumor antigen-specific CD4+ T cells for antileukemia adoptive immunotherapy.
- Author(s)
  Hiroshi Fujiwara et al.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] モガムリツマブと人工CD16陽性T細胞を併用した成人T細胞白血病に対する新規治療法開発.
- Author(s)
  田中寛希、藤原　弘*、谷本一史、越智史博、安川正貴
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] 移植と抗腫瘍免疫療法
- Author(s)
  藤原　弘*
- Organizer
  第37回　日本造血細胞移植学会総会教育講演3
- Place of Presentation
  神戸市
- Year and Date
  2015-03-05 – 2015-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] ポテリジオを併用したATLに対する新たな細胞免疫療法の可能性.
- Author(s)
  田中寛希、藤原　弘*、越智史博、谷本一史、朝井洋晶、那波明宏、安川正貴
- Organizer
  第76回　日本血液学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Generation of high-quality TCR-gene modified T cells using siTCR lentiviral vector combined with anti-CD3/CH296 stimulation and transduction method.
- Author(s)
  Okamoto S, Isoe K, Amaishi Y, Shimomura M, Ikeda H, Fujiwara H*, Yasukawa M, Shiku H, Mineno J.
- Organizer
  American Society of Gene & Cell Therapy, 17th Annual Meeting
- Place of Presentation
  Washington DC
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] 抗体療法と細胞療法を組み合わせたハイブリッド型抗腫瘍免疫療法の開発研究。
- Author(s)
  藤原　弘　他
- Organizer
  第5回造血器腫瘍免疫療法研究会学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Development of HLA class I-restricted Th1 and Th17 CD4+ T cells gene-modified to target WT1.
- Author(s)
  朝井洋晶、藤原　弘*、越智俊元、岡本幸子、峰野純一、葛島清隆、珠玖　洋、安川正貴
- Organizer
  第76回　日本血液学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Redirected T-cell based adoptive immunotherapy for human leukemia; where we are now and where we will go next.
- Author(s)
  Hiroshi Fujiwara.
- Organizer
  Lecture at Hematology Branch, NHLBI/NIH
- Place of Presentation
  Hematology Branch, National Heart, Lung and Blood Institute/ NIH, Bethesda, MA
- Invited
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] HLA class I拘束性WT1特異的Th1及びTh17 CD4+ T細胞作製の試み.
- Author(s)
  朝井洋晶、藤原　弘*、越智俊元、岡本幸子、峰野純一、葛島清隆、珠玖　洋、安川正貴
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Targeting Aurora Kinase A with an enhanced TCR gene-transfer vector.
- Author(s)
  Nicholas Casey、藤原　弘*、岡本幸子、峰野純一、葛島清隆、珠玖　洋、安川正貴
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Myeloid leukemia cells suppress T cell proliferation.
- Author(s)
  谷本一史、藤原　弘*、安川正貴
- Organizer
  第73回日本癌学会学術集会（English oral session）
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] High-quality TCR-gene modified T cells using siTCR lentiviral vector in combination with anti-CD3/CH296 stimulation.
- Author(s)
  岡本幸子、礒江加奈子、池田裕明、藤原　弘*、安川正貴、珠玖　洋、峰野純一
- Organizer
  第20回日本遺伝子治療学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Aurora Kinase-A vaccination therapy in leukemia patients.
- Author(s)
  谷本一史、藤原　弘*、宮崎幸大、越智俊元、朝井洋晶、山之内　純、東　大地、羽藤高明、安川正貴
- Organizer
  第76回　日本血液学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24591426
[Presentation] Myeloid leukemia cells suppress T cell proliferation.
- Author(s)
  谷本一史、Miner Samantha、伊藤沙和、Pawel Muranski、藤原　弘*、Nancy Hensel、J.Joseph Melenhorst、A John Barrett、安川正貴
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山市
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24591426

1. YASUKAWA Masaki (60127917)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
2. 赤堀泰 (80221711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 三輪啓志 (00209967)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 瀬尾尚宏 (50283354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 齋藤佳菜子 (90447871)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 小塚祐司 (50378311)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 石原幹也 (20707369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. HASEGAWA Hitoshi (40164826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Tanimoto Kazushi (40724779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
10. Ikegame Kazuhiro (20372609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 福永景子 (60649185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 百瀬文康 (20798326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小川朋子 (90362334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 吉原哲 (90461037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 玉置広哉 (70416254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 加藤琢磨 (60224515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. OKAMURA Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. WANG Linan

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. ISHIDA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. ITO Asahi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. TERAMACHI Jyumpei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. KURATA Mie

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. MASUYA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 葛島清隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 太田里永子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 赤塚美樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 宮本敏浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 小川啓恭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 夏目敦至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 朝井洋晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujiwara Hiroshi 藤原 弘

FUJIWARA Hiroshi 藤原 弘

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Aim to eliminate a bottleneck in the practical realization of anticancer immunotherapy with gene-modified allogeneic gammadelta T cells.Principal Investigator

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Development of novel anti-leukemia immunotherapy using neo-antigen specific CD4 helper T cellsPrincipal Investigator

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Therapeutic employment of leukemia-reactive CD4-CD8 T-cell network aiming at improved clinical efficacy.Principal Investigator

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Development of a novel antileukemia adoptive immunotherapy using leukemia-reactive gene-modified memory T cells.Principal Investigator

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Attempts to answer the crucial qeustion if the anti-tumor cellular immune system can eradicate leukemia stem cells-an analysis using humanized mouse system-Principal Investigator

Fujiwara Hiroshi 藤原弘

FUJIWARA Hiroshi 藤原弘