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ADACHI Jun  足立 淳

… Alternative Names

足立 淳  アダチ ジュン

Less
Researcher Number 20437255
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-1220-3246
Affiliation (Current) 2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, 副センター長
Affiliation (based on the past Project Information) *help 2023 – 2024: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, 副センター長
2018 – 2022: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, プロジェクトリーダー
2017: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 プロテオームリサーチプロジェクト, 上席研究員
2016: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 プロテオームリサーチプロジェクト, サブプロジェクトリーダー
2016: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 プロテオームリサーチプロジェクト, プロジェクト研究員 … More
2015: 国立研究開発法人医薬基盤・健康・栄養研究所, その他部局等, 研究員
2015: 国立研究開発法人医薬基盤・健康・栄養研究所, プロテオームリサーチプロジェクト, 研究員
2015: 医薬基盤・健康・栄養研究所, プロテオームリサーチプロジェクト, 研究員
2015: 国立研究開発法人医薬基盤・健康・栄養研究所, 創薬基盤研究部, プロジェクト研究員
2013 – 2014: 独立行政法人医薬基盤研究所, 創薬基盤研究部, 研究員
2012 – 2014: 独立行政法人医薬基盤研究所, その他部局等, 研究員
2012 – 2014: 独立行政法人医薬基盤研究所, 創薬基盤研究部, プロジェクト研究員
2011: 独立行政法人医薬基盤研究所, プロテオームリサーチセンター, 研究員
2007 – 2009: Kyoto University, 地球環境学堂, 助教 Less
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics / Tumor diagnostics / Risk sciences of radiation/Chemicals / Structural biochemistry
Except Principal Investigator
Tumor diagnostics / Basic Section 48040:Medical biochemistry-related / Basic Section 53010:Gastroenterology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 63020:Radiation influence-related / Basic Section 50010:Tumor biology-related / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals
Keywords
Principal Investigator
プロテオミクス / プロテオーム / リン酸化プロテオミクス / キナーゼ阻害剤 / リン酸化 / シグナル伝達 / 質量分析 / 翻訳後修飾 / 大腸がん / 化学療法耐性 … More / 大腸癌肝転移 / 薬剤反応性 / 酵素反応 / 酵素活性 / 分子標的 / 食道がん / キナーゼ / ユビキチン化 / DNA損傷応答 … More
Except Principal Investigator
KRAS / バイオマーカー / 大腸癌 / HOX遺伝子 / 急性白血病 / ヌクレオポリン融合遺伝子 / ゲノム高次構造 / 相分離 / 白血病 / 融合遺伝子 / 次世代シークエンス / 治療抵抗性の克服 / リン酸化プロテオゲノミクス解析 / BRAFV600E変異陽性大腸癌 / リン酸プロテオミクス / リン酸化プロテオミクス / 生検組織 / 精密医療 / がん多様性 / リン酸化プロテオーム解析 / ゲノム不安定性 / 癌遺伝子 / 発がん機構 / DNA複製ストレス / Lung cancer / genome instability / DNA replication stress / ATR / 体細胞変異 / 遺伝的背景 / 遺伝学的背景 / 家族性大腸腺腫症 / MEK阻害剤 / IFN/STATシグナル / 大腸がん / 患者由来オルガノイド / 膜タンパク質 / 癌転移 / プロテオミクス / マイクロアレイ / 生物影響 / 遮蔽 / 自然放射線 / 次世代DNAシーケンサー / タンパク質複合体解析 / DNAアダクトーム / ヒストンH2AX / 変異原試験 / ヒストン修飾 / プロテオーム / クロマチン / DNA損傷応答 / 小核試験 / SMRTシーケンサー / 1分子リアルタイムDNAシーケンサー / 遺伝毒性試験 / 染色体異常 / DNA損傷 / 突然変異 Less
  • Research Projects

    (14 results)
  • Research Products

    (67 results)
  • Co-Researchers

    (23 People)
  •  The novel roles of nuclear bodies formed by nucleoporin fusion proteins

    • Principal Investigator
      岡 正啓
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Osaka University
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Using phosphoproteogenomics analysis to elucidate resistance to therapy in BRAF mutated colorectal cancer

    • Principal Investigator
      庄司 広和
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      National Cancer Center Japan
  •  Elucidation of cancer diversity mechanism by analysis of phosphorylation signal using biopsy tissue and application to precision medicine

    • Principal Investigator
      Tomonaga Takeshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Elucidation of chemoresistance-resistant signal mechanism of colon cancer liver metastasisPrincipal Investigator

    • Principal Investigator
      ADACHI JUN
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Genetic- and Somatic-regualtion of colorectal cancer

    • Principal Investigator
      YAO Ryoji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Elucidation of the mechanism underlying tumor initiation via DNA replication stress regulated by ATR

    • Principal Investigator
      Shiotani Bunsyo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 63020:Radiation influence-related
    • Research Institution
      National Cancer Center Japan
  •  ATP turnover proteomics for cancer drug target discoveryPrincipal Investigator

    • Principal Investigator
      ADACHI JUN
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Tumor therapeutics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Biomarker discovery of colorectal cancer metastasis from cancer tissues and verification in plasma exosomes by targeted proteomics.

    • Principal Investigator
      Shiromizu Takashi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  In situ pharmacoproteomics for the prediction of efficacy and side effectsPrincipal Investigator

    • Principal Investigator
      ADACHI JUN
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor diagnostics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Comprehensive functional analysis of colorectal cancer biomarker candidates for the exploitation of diagnostic and therapeutic methods

    • Principal Investigator
      Hara Yasuhiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Osaka University
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Molecular mechanism of growth retardation of mouse cells by shielding them from background radiation

    • Principal Investigator
      KAWANISHI Masanobu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Osaka Prefecture University
  •  High-sensitive proteomic analysis of proteins modified in response to DNA damage.Principal Investigator

    • Principal Investigator
      ADACHI Jun
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      独立行政法人医薬基盤研究所
  •  Innovation of genotoxicity tests - DNA damage, Mutation, Chromosome -

    • Principal Investigator
      Matsuda Tomonari
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Kyoto University
  •  未知翻訳後修飾にも対応する翻訳後修飾の一斉定量分析法の開発Principal Investigator

    • Principal Investigator
      足立 淳
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation Patent

  • [Journal Article] Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure2023

    • Author(s)
      Oka Masahiro、Otani Mayumi、Miyamoto Yoichi、Oshima Rieko、Adachi Jun、Tomonaga Takeshi、Asally Munehiro、Nagaoka Yuya、Tanaka Kaori、Toyoda Atsushi、Ichikawa Kazuki、Morishita Shinichi、Isono Kyoichi、Koseki Haruhiko、Nakato Ryuichiro、Ohkawa Yasuyuki、Yoneda Yoshihiro
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 8 Pages: 112884-112884

    • DOI

      10.1016/j.celrep.2023.112884

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0111, KAKENHI-PROJECT-22K19275, KAKENHI-PLANNED-19H05745, KAKENHI-PUBLICLY-22H04676, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23H00372, KAKENHI-PROJECT-23K27373
  • [Journal Article] Integration of pharmacoproteomic and computational approaches reveals the cellular signal transduction pathways affected by apatinib in gastric cancer cell lines.2023

    • Author(s)
      Nojima, Y., Aoki, M., Re, S., Hirano, H., Abe, Y., Narumi, R., Muraoka, S., Shoji, H., Honda, K., Tomonaga, T., Mizuguchi, K., Boku, N., and Adachi, J.
    • Journal Title

      Comput Struct Biotechnol J

      Volume: 21 Pages: 2172-2187

    • DOI

      10.1016/j.csbj.2023.03.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03544, KAKENHI-PROJECT-20K07333, KAKENHI-PROJECT-20K15422, KAKENHI-PROJECT-20K17069, KAKENHI-PROJECT-23K20389, KAKENHI-PROJECT-22K08068
  • [Journal Article] Temporal dynamics from phosphoproteomics using endoscopic biopsy specimens provides new therapeutic targets in stage IV gastric cancer2022

    • Author(s)
      Hirano H, Abe Y, Nojima Y, Aoki M, Shoji H, Isoyama J, Honda K, Boku N, Mizuguchi K, Tomonaga T, Adachi J.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 4419-4419

    • DOI

      10.1038/s41598-022-08430-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08432, KAKENHI-PROJECT-20H03544, KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-20K15422, KAKENHI-PROJECT-20K07333, KAKENHI-PROJECT-20K17069, KAKENHI-PROJECT-23K20389, KAKENHI-PROJECT-19H03856
  • [Journal Article] Systematic identification of ALK substrates by integrated phosphoproteome and interactome analysis.2022

    • Author(s)
      Adachi, J., Kakudo, A., Takada, Y., Isoyama, J., Ikemoto, N., Abe, Y., Narumi, R., Muraoka, S., Gunji, D., Hara, Y., Katayama, R., and Tomonaga, T.
    • Journal Title

      Life Sci Alliance

      Volume: 5 Issue: 8 Pages: e202101202-e202101202

    • DOI

      10.26508/lsa.202101202

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03544, KAKENHI-PROJECT-20K07333, KAKENHI-PROJECT-23K20389
  • [Journal Article] Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens.2020

    • Author(s)
      Abe Y, Hirano H, Shoji H, Tada A, Isoyama J, Kakudo A, Gunji D, Honda K, Boku N, Adachi J, Tomonaga T.
    • Journal Title

      Theranostics

      Volume: 10(5) Issue: 5 Pages: 2115-2129

    • DOI

      10.7150/thno.37623

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08432, KAKENHI-PROJECT-20H03544, KAKENHI-PROJECT-19H03856
  • [Journal Article] Improved phosphoproteomic analysis for phosphosignaling and active-kinome profiling in Matrigel-embedded spheroids and patient-derived organoids2018

    • Author(s)
      Abe Yuichi、Tada Asa、Isoyama Junko、Nagayama Satoshi、Yao Ryoji、Adachi Jun、Tomonaga Takeshi
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 11401-11401

    • DOI

      10.1038/s41598-018-29837-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-16H04707, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-16H06150, KAKENHI-PROJECT-16K14620, KAKENHI-PROJECT-17K15014
  • [Journal Article] Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics2017

    • Author(s)
      Shiromizu Takashi、Kume Hideaki、Ishida Mimiko、Adachi Jun、Kano Masayuki、Matsubara Hisahiro、Tomonaga Takeshi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 12782-12782

    • DOI

      10.1038/s41598-017-13092-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06865, KAKENHI-PROJECT-16K15626
  • [Journal Article] Coordinated regulation of TIP60 and PARP-1 in damaged chromatin dynamics.2016

    • Author(s)
      Ikura M
    • Journal Title

      Mol. Cell. Biol.

      Volume: Epub ahead of print Issue: 10 Pages: 1595-1607

    • DOI

      10.1128/mcb.01085-15

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12203, KAKENHI-PUBLICLY-15H01181, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-26550028, KAKENHI-PROJECT-26281020
  • [Journal Article] Data for Proteomic Analysis of ATP-Binding Proteins and Kinase Inhibitor Target Proteins Using an ATP Probe.2015

    • Author(s)
      Adachi, J., Kishida, M., Watanabe, S., Hashimoto, Y., Fukamizu, K., and Tomonaga, T.
    • Journal Title

      Data in Brief

      Volume: 5 Pages: 726-729

    • DOI

      10.1016/j.dib.2015.10.018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-26640098, KAKENHI-PROJECT-26670614, KAKENHI-PROJECT-25290054
  • [Journal Article] Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor.2015

    • Author(s)
      Shun Matsuda, Jun Adachi, Masaru Ihara, Nobuhiro Tanuma, Hiroshi Shima, Akira Kakizuka, Masae Ikura, Tsuyoshi Ikura, Tomonari Matsuda
    • Journal Title

      Nucleic Acids Res

      Volume: 44(2) Issue: 2 Pages: 636-647

    • DOI

      10.1093/nar/gkv967

    • NAID

      120005818255

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430130, KAKENHI-PROJECT-15K12203, KAKENHI-PUBLICLY-15H01181, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-26550028, KAKENHI-PROJECT-26281020
  • [Journal Article] Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged Chromatin.2015

    • Author(s)
      Ikura M
    • Journal Title

      Mol. cell. Biol.

      Volume: 35 Issue: 24 Pages: 4147-4157

    • DOI

      10.1128/mcb.00757-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12203, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-26550028, KAKENHI-PROJECT-26281020
  • [Journal Article] Proteome-wide discovery of unknown ATP-binding proteins and kinase inhibitor target proteins using an ATP probe.2014

    • Author(s)
      Jun Adachi, Marina Kishida, Shio Watanabe, Yuuki Hashimoto, Kazuna Fukamizu, Takeshi Tomonaga.
    • Journal Title

      Journal of proteome research

      Volume: 13 Issue: 12 Pages: 5461-5470

    • DOI

      10.1021/pr500845u

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-24681009, KAKENHI-PROJECT-25290054, KAKENHI-PROJECT-26640098, KAKENHI-PROJECT-26670614
  • [Journal Article] A novel mechanism of keratin cytoskeleton organization through casein kinase I alpha and FAM83H in colorectal cancer.2013

    • Author(s)
      Kuga, T., Kume, H., Kawasaki, N., Sato, M., Adachi, J., Shiromizu, T., Hoshino, I., Nishimori, T., Matsubara, H., and Tomonaga T.
    • Journal Title

      J Cell Sci

      Volume: 126 Pages: 4721-31

    • DOI

      10.1242/jcs.129684

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659622, KAKENHI-PROJECT-24681009, KAKENHI-PROJECT-24790184, KAKENHI-PROJECT-25290054, KAKENHI-PROJECT-25460715, KAKENHI-PROJECT-25871241
  • [Journal Article] A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair2013

    • Author(s)
      J Tomida, A Itaya, T Shigechi, J Unno, E Uchida, M Ikura, Y Masuda, S Matsuda J Adachi, M Kobayashi, AR Meetei, Y Maehara, K Yamamoto K Kamiya, A Matsuura, T Matsuda. T Ikura, M Ishiai, M Takata
    • Journal Title

      Nucleic Acids Research

      Volume: VOL. 41 Issue: 14 Pages: 6930-6941

    • DOI

      10.1093/nar/gkt467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05844, KAKENHI-PLANNED-22131004, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-24310040, KAKENHI-PROJECT-24310042, KAKENHI-PUBLICLY-25131706, KAKENHI-PROJECT-25281020, KAKENHI-PROJECT-25550031
  • [Patent] 難治性癌に対する治療薬の探索方法2023

    • Inventor(s)
      足立淳、朝長毅、軍司大悟
    • Industrial Property Rights Holder
      足立淳、朝長毅、軍司大悟
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-074693
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] Phosphoproteomic subtyping of gastric cancer reveals dynamic transformation with chemotherapy2023

    • Author(s)
      Hirokazu Shoji, Masahiko Aoki, Hidekazu Hirano, Yuichi Abe, Ryohei Narumi, Kazufumi Honda, Takeshi Tomonaga, Kenji Mizuguchi, Takaki Yoshikawa, Narikazu Boku, and Jun Adachi
    • Organizer
      AACR2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08068
  • [Presentation] Phosphoproteomic subtyping of gastric cancer reveals dynamic transformation with chemotherapy2023

    • Author(s)
      Hirokazu Shoji, Masahiko Aoki, Hidekazu Hirano, Yuichi Abe, Ryohei Narumi, Kazufumi Honda, Takeshi Tomonaga, Kenji Mizuguchi, Takaki Yoshikawa, Narikazu Boku, and Jun Adachi
    • Organizer
      AACR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08068
  • [Presentation] リン酸化プロテオミクスと公共薬剤感受性データの統合解析による薬剤耐性大腸がん肝転移巣の新規創薬探索2022

    • Author(s)
      軍司大悟、阿部 雄一、長山聡、坂井 義治、小濵 和貴、朝長毅、足立淳
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] リン酸化プロテオミクスと公共薬剤感受性データの統合解析による薬剤耐性大腸がん肝転移巣の新規創薬探索2022

    • Author(s)
      軍司大悟、阿部 雄一、長山聡、坂井 義治、小濵 和貴、朝長毅、足立淳
    • Organizer
      日本プロテオーム学会2022年大会
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] リン酸化プロテオームデータと薬剤感受性データの統合解析による薬剤耐性大腸がん肝転移巣の新規治療標的探索2022

    • Author(s)
      軍司大悟、阿部 雄一、長山聡、坂井 義治、小濵 和貴、朝長毅、足立淳
    • Organizer
      第42回 日本分子腫瘍マーカー研究会
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] リン酸化シグナル解析を用いたがん個別化医療への展開2022

    • Author(s)
      足立淳
    • Organizer
      第19回北里疾患プロテオーム研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03530
  • [Presentation] リン酸化プロテオーム解析とインタラクトーム解析を組み合わせたALKキナーゼの 基質同定2022

    • Author(s)
      足立淳、覚道 明美、高田洋子、池本 成美、磯山純子、阿部 雄一 、鳴海 良平、村岡 賢、軍司 大悟、原 康弘、片山量平、朝長毅
    • Organizer
      日本プロテオーム学会2022年大会
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] Identification of ALK substrate candidates by the combination of phosphoproteome and interactome analysis.2021

    • Author(s)
      足立淳、朝長毅
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] リン酸化シグナル解析を用いたがん個別化医療への展開2021

    • Author(s)
      足立淳
    • Organizer
      第75回 NPO法人日本口腔科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03530
  • [Presentation] リン酸化シグナル解析を用いたがん個別化医療への展開2020

    • Author(s)
      足立淳
    • Organizer
      第16回日本臨床プロテオゲノミクス研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03530
  • [Presentation] Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens.2020

    • Author(s)
      Shoji H, Abe Y, Hirano H, Adachi J, Aoki M, Honda K, Boku N, Tomonaga T
    • Organizer
      2020 ASMS Reboot
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens.2020

    • Author(s)
      Shoji H, Abe Y, Hirano H, Adachi J, Aoki M, Honda K, Boku N, Tomonaga T.
    • Organizer
      AACR Annual Meeting 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] Combination of phosphoproteomic data, drug sensitivity data, gene dependency data reveals potential therapeutic targets.2020

    • Author(s)
      Adachi J, Tomonaga T
    • Organizer
      第79回日本がん学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03544
  • [Presentation] プロテオミクスを駆使したがん最適医療への挑戦2019

    • Author(s)
      足立淳
    • Organizer
      第25回日本質量分析学会北海道談話会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06150
  • [Presentation] Quantitative proteomic analysis of colorectal cancer liver metastases resistant to postoperative adjuvant chemothrapy.2019

    • Author(s)
      軍司 大悟、阿部雄一、朝長毅、長山聡、足立淳
    • Organizer
      日本プロテオーム学会2019年大会 第70回日本電気泳動学会総会
    • Data Source
      KAKENHI-PROJECT-19H03530
  • [Presentation] Phosphoproteomics of non-small-cell lung cancer cells treated with erlotinib reveals drug-resistant signatures and potential targets.2018

    • Author(s)
      J. Adachi, Y. Abe, M. Nagano, J. Isoyama, M. Kishida, T. Tomonaga
    • Organizer
      THE 22nd INTERNATIONAL MASS SPECTROMETRY CONFERENCE (IMSC) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06150
  • [Presentation] リン酸化プロテオーム解析を用いた肺がん細胞株の薬剤応答解析2017

    • Author(s)
      足立 淳
    • Organizer
      第65回質量分析総合討論会
    • Data Source
      KAKENHI-PROJECT-16H06150
  • [Presentation] 血中細胞外小胞を用いた新規大腸がんマーカー候補タンパク質の探索とターゲットプロテオミクスによる評価2017

    • Author(s)
      白水崇、石田美海子、足立淳、朝長毅
    • Organizer
      日本プロテオーム学会2017年大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] Phosphoproteomics of non-small-cell lung cancer cells reveals drug-resistant signatures and potential targets.2017

    • Author(s)
      足立 淳、朝長 毅
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H06150
  • [Presentation] Acid-based SCX fractionation for in-depth proteome and phosphoproteome analysis2016

    • Author(s)
      Jun Adachi, Kazunari Hashiguchi, Misako Sato, Kazuna Fukamizu, Yasushi Ishihama, Takeshi Tomonaga
    • Organizer
      the 64th ASMS Conference
    • Place of Presentation
      サンアントニオ、米国
    • Year and Date
      2016-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06150
  • [Presentation] 大腸癌転移性株の定量的プロテオーム解析による新規転移因子の探索およびSRM/MRM法による検証2016

    • Author(s)
      白水崇、足立淳、朝長毅
    • Organizer
      日本プロテオーム学会2016年大会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] Proteomic analysis of metastatic colorectal cancer cell and verification by SRM/MRM analysis.2016

    • Author(s)
      Takashi Shiromizu, Jun Adachi and Takeshi Tomonaga.
    • Organizer
      15th Human Proteome Organization World Congress
    • Place of Presentation
      台湾
    • Year and Date
      2016-09-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] エルロチニブ処理時の非小細胞肺癌培養細胞株におけるリン酸化経時変化大規模情報の取得と活用2016

    • Author(s)
      足立 淳、阿部雄一、朝長 毅
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16H06150
  • [Presentation] Acid-based SCX fractionation for in-depth proteome and phosphoproteome analysis2016

    • Author(s)
      Jun Adachi, Kazunari Hashiguchi, Misako Sato, Kazuna Fukamizu, Yasushi Ishihama, Takeshi Tomonaga
    • Organizer
      HUPO 15th Annual World Congress
    • Place of Presentation
      台北、台湾
    • Year and Date
      2016-09-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06150
  • [Presentation] C18-SCX StageTipを用いた新規ペプチド分画法の開発2015

    • Author(s)
      足立淳、橋口一成、佐藤美佐子、長野麻衣子、橋本裕希、深水和菜、佐藤彩子、石濱泰、朝長毅
    • Organizer
      日本プロテオーム学会
    • Place of Presentation
      熊本市
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] Mass spectrometry-based quantitative proteome analysis of histone modifications and chromatin proteins2015

    • Author(s)
      足立淳、朝長毅
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] ピルビン酸キナーゼとピルビン酸デヒドロゲナーゼ複合体によるアセチルCoAの地産地消モデル2015

    • Author(s)
      松田俊, 足立淳, 井原賢, 田沼延公, 島礼, 垣塚彰, 井倉正枝, 井倉毅, 松田知成
    • Organizer
      日本生化学会大会
    • Place of Presentation
      神戸市
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] ATP Accessibility Screening (AAS), a high-throughput and high-resolution kinase analysis platform for signaling research2013

    • Author(s)
      1. Adachi J, Higo D, Kishida M, Watanabe S, Kuwano M, Hashimoto Y, Fukamizu K, Nishiwaki E, Tomonaga T
    • Organizer
      Human Proteome Organization (HUPO) 12th annual congress
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] ATP Accessibility Screening (AAS), a high-throughput and high-resolution kinase analysis platform for signaling research2013

    • Author(s)
      Adachi, J., Higo, D., Kishida, M., Watanabe, S., Kuwan, M., Hashimoto, Y., Fukamizu, K., Nishiwaki, E., Tomonaga, T.
    • Organizer
      Human Proteome Organization (HUPO) 12th annual congress
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] リン酸化プロテオミクスを用いた新規DNA損傷初期応答キナーゼの探索2012

    • Author(s)
      足立淳
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] Discovery of early-response kinases in DNA-damage signaling using phosphoproteome analysis2012

    • Author(s)
      足立淳
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] リン酸化プロテオミクスを用いた新規DNA損傷初期応答キナーゼの探索2012

    • Author(s)
      足立淳
    • Organizer
      日本プロテオーム学会2012
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] リン酸化プロテオミクスを用いた新規DNA損傷初期応答キナーゼの探索2012

    • Author(s)
      足立淳
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      仙台(招待講演)
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] リン酸化プロテオミクスを用いた新規DNA損傷初期応答キナーゼの探索2012

    • Author(s)
      足立淳
    • Organizer
      日本プロテオーム学会2012年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] DNA損傷初期応答シグナル解析から創薬標的の探索へ2012

    • Author(s)
      足立淳
    • Organizer
      第10回北里疾患プロテオーム研究会
    • Place of Presentation
      神奈川
    • Year and Date
      2012-08-23
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] ATP Accessibility Screening (AAS), a high-throughput and high-resolution kinase analysis platform for signaling research2012

    • Author(s)
      Jun Adachi
    • Organizer
      2nd Copenhagen Bioscience Conference
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] Global phosphorylation and ubiquitination dynamics in DNA-damage response network2012

    • Author(s)
      Jun Adachi
    • Organizer
      Asia Oceania Human Proteome Organization (AOHUPO)6th congress
    • Place of Presentation
      Beijing, China
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] Phosphorylation dynamics in an early response of DNA damage signaling2012

    • Author(s)
      Jun Adachi
    • Organizer
      HUPO2012
    • Place of Presentation
      Boston, U.S.A
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] Phosphorylation dynamics in an early response of DNA damage signaling2012

    • Author(s)
      足立淳
    • Organizer
      HUPO2012 11th World Congress
    • Place of Presentation
      米国 ボストン
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] リン酸化プロテオミクスを用いた新規DNA損傷初期応答キナーゼの探索2012

    • Author(s)
      足立淳
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] リン酸化プロテオミクスを用いた新規DNA損傷初期応答キナーゼの探索2011

    • Author(s)
      足立淳, ら
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] Bioinformatics-GO annotation-2011

    • Author(s)
      足立淳
    • Organizer
      日本プロテオーム学会2011年会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] DNA損傷応答におけるリン酸化・ユビキチン化プロテオーム定量解析2011

    • Author(s)
      足立淳, ら
    • Organizer
      日本プロテオーム学会2011年会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] Global phosphorylation and ubiquitination dynamics in DNA-damage response network2011

    • Author(s)
      足立淳, ら
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場・名古屋市
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] Oxidative modificomics analysis of cysteine thiols2009

    • Author(s)
      Jun Adachi, Keishi Kihara, Tomonari Matsuda
    • Organizer
      10th International Conference on Environmental Mutagens
    • Place of Presentation
      国際会議場 (イタリア・フィレンツェ)
    • Year and Date
      2009-08-22
    • Data Source
      KAKENHI-PROJECT-19657032
  • [Presentation] Unbiased quantification of oxidative modifications of cysteine thiols by double labeling approach using isotope amino acids and affinity Tags (DLIAA).2008

    • Author(s)
      Jun Adachi, Keishi Kihara, Tomonari Matsuda
    • Organizer
      日本環境変異原学会第37回大会
    • Place of Presentation
      沖縄県宜野湾市
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-19657032
  • [Presentation] The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane2007

    • Author(s)
      足立淳
    • Organizer
      HUPO2007 urine and kidney proteome initiative
    • Place of Presentation
      韓国・ソウルKOEX
    • Year and Date
      2007-10-06
    • Data Source
      KAKENHI-PROJECT-19657032
  • [Presentation] Kinome and ATPome-wide selectivity profiling of ATP-competitive kinase inhibitors.

    • Author(s)
      Adachi, J., Tomonag, T.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] Kinome and ATPome-wide selectivity profiling of ATP-competitive kinase inhibitors.

    • Author(s)
      Jun Adachi, Takeshi Tomonaga
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24681009
  • [Presentation] Simplified and minimized fractionation using StageTips for in-depth proteome and phosphoproteome analysis

    • Author(s)
      Adachi, J., Hashiguchi, K., Sato, M., Fukamizu, K., Tomonaga, T.
    • Organizer
      HUPO2014 13th World Congress
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2014-10-05 – 2014-10-08
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] StageTipを用いた新規分画法により、プロテオーム解析・リン酸化プロテオーム解析の深さと簡易性の両立を図る

    • Author(s)
      足立淳、橋口一成、佐藤美佐子、橋本裕希、深水和菜、朝長毅
    • Organizer
      日本プロテオーム学会2014年会
    • Place of Presentation
      つくば市
    • Year and Date
      2014-07-17 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-23221006
  • [Presentation] Kinome and ATPome-wide selectivity profiling of ATP-competitive kinase inhibitors.

    • Author(s)
      Jun Adachi, Takeshi Tomonaga
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26640098
  • 1.  TOMONAGA Takeshi (80227644)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 16 results
  • 2.  長山 聡 (70362499)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 3.  Matsuda Tomonari (50273488)
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    # of Collaborated Products: 1 results
  • 4.  Ikura Tsuyoshi (70335686)
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    # of Collaborated Products: 3 results
  • 5.  KAWANISHI Masanobu (70332963)
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  • 6.  SHIRAISHI Kazunori (40347513)
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  • 7.  YAGI Takashi (80182301)
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  • 8.  Shiromizu Takashi (00582678)
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  • 9.  Hara Yasuhiro (70568617)
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  • 10.  YAO Ryoji (80291095)
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  • 11.  Shiotani Bunsyo (10627665)
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  • 12.  久米 秀明 (50322714)
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  • 13.  野村 大成 (90089871)
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  • 14.  朴 成和 (50505948)
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  • 15.  佐藤 友美 (10333353)
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  • 16.  庄司 広和 (50765568)
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  • 17.  本田 一文 (10260936)
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  • 18.  岡 正啓 (40432504)
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  • 19.  中戸 隆一郎 (60583044)
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  • 20.  SHOJI Satoshi
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  • 21.  IKURA Masae
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    # of Collaborated Products: 2 results
  • 22.  宮本 洋一
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  • 23.  島 礼
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