Imoto Shuhei 井本修平

… Alternative Names

井本修平イモトシュウヘイ

IMOTO Syuhei 井本修平

IMOTO Shuhei 井本修平

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Researcher Number	20447189
Other IDs
Affiliation (Current)	2025: 崇城大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2024: 崇城大学, 薬学部, 教授 2022: 崇城大学, 薬学部, 教授 2020 – 2021: 崇城大学, 薬学部, 准教授 2011 – 2012: 崇城大学, 薬学部, 講師 2011: 東北大学, 多元物質科学研究所, 助教 2007 – 2009: 東北大学, 多元物質科学研究所, 助教
Review Section/Research Field	Principal Investigator Drug development chemistry Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Chemistry related to living body / Drug development chemistry / Science and Engineering
Keywords	Principal Investigator クロスリンク / RNA修飾 / 人工核酸 / 核酸修飾 / 架橋反応 / RNA 修飾 Except Principal Investigator アルブミン / 一酸化窒素 / 膵臓がん / 遺伝子発現制御 … More / RNA標的 / In Cell Chemistry / オリゴDNA / クロスリンク / クロスリンク反応 / 核酸・蛋白質・糖化学 / ドラッグデリバリー / NOラジカル / 膵がん / フェニル酪酸 / ニトロ化合物 / オートファジー / がん治療 / 細胞死 / DNA変異 / DNA修飾 / 人工核酸 / インテリジェント核酸 / miRNA / 薬物放出システム / ハイブリダイゼーション / インベージョン / ペプチド核酸 / ランダムスクリーニング / コンビケム / インターカレーター / DNA高次構造 / クリックケミストリー / ペプチド Less

Development of NO donors with high albumin affinity for treatment of pancreatic cancer
- Principal Investigator
  
  西弘二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Sojo University
Development of albumin-binding nitric oxide donors for treatment of pancreatic cancer
- Principal Investigator
  
  Nishi Koji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Sojo University
G:C→A:T変異を誘導する人工核酸ツールの開発
- Principal Investigator
  
  國枝武久
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Sojo University
Development of methodology for site-specific RNA modification using the Reactive OligonucleotidesPrincipal Investigator
- Principal Investigator
  
  IMOTO Shuhei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Sojo University
Development of the Functional Molecules for Genome Targeting Chemistry
- Principal Investigator
  
  NAGATSUGI Fumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Tohoku University
細胞内におけるDNA高次構造認識分子の開発
- Principal Investigator
  
  NAGATSUGI Fumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Application of the Activated Reaction by Hybridization to Target Genes for the Regulation of Gene Expression in Cells
- Principal Investigator
  
  NAGATSUGI Fumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Tohoku University

All 2022 2021 2020 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] Novel nitric oxide donor, nitrated phenylbutyrate, induces cell death of human pancreatic cancer cells and suppresses tumor growth of cancer xenografts2022
- Author(s)
  Beppu Takuro、Nishi Koji、Imoto Shuhei、Araki Waka、Setoguchi Itaru、Ueda Ayaka、Suetsugi Naho、Ishima Yu、Ikeda Tokunori、Otagiri Masaki、Yamasaki Keishi
- Journal Title
  
  Oncology Reports
  
  Volume: 48 Issue: 4 Pages: 178-178
- DOI
  10.3892/or.2022.8393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-20K07193, KAKENHI-PROJECT-21K19716, KAKENHI-PROJECT-20K06995
[Journal Article] The Nitrated Form of Nateglinide Induces Apoptosis in Human Pancreatic Cancer Cells Through a Caspase-dependent Mechanism.2022
- Author(s)
  Nishi K, Imoto S, Beppu T, Uchibori S, Yano A, Ishima YU, Ikeda T, Tsukigawa K, Otagiri M, Yamasaki K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 42 Issue: 3 Pages: 1333-1338
- DOI
  10.21873/anticanres.15601
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07193, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-20K06995
[Journal Article] Production of truncated protein by the crosslink formation of mRNA with 2’-OMe oligoribonucleotide containing 2-amino-6-vinylpurine2012
- Author(s)
  Hagihara, S., Kusano, S., Lin, W.C., Chao, X.G., Hori, T., Imoto, S., Nagatsugi, F.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Issue: 12 Pages: 3870-3872
- DOI
  10.1016/j.bmcl.2012.04.123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659002, KAKENHI-PROJECT-23750180, KAKENHI-PROJECT-23790146, KAKENHI-PUBLICLY-24102508, KAKENHI-PUBLICLY-24115701
[Journal Article] Fast DNA Interstrand Cross-linking Reaction by 6-Vinylpurine2012
- Author(s)
  Imoto, S., Chikuni, T., Kansui, H, Kunieda, T. , Nagatsugi, F.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids.
  
  Volume: 31 Issue: 10 Pages: 752-762
- DOI
  10.1080/15257770.2012.726756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659002, KAKENHI-PROJECT-23790146, KAKENHI-PUBLICLY-24102508
[Journal Article] Imoto Induced cross-linking reactions to target genes using modified oligonucleotides2011
- Author(s)
  F.Nagatsugi,and S.
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 9 Issue: 8 Pages: 2579-2585
- DOI
  10.1039/c0ob00819b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659002, KAKENHI-PROJECT-23790146
[Journal Article] Induced cross-linking reactions to target genes using modified oligonucleotides2011
- Author(s)
  F. Nagatsugi, and S. Imoto
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 9 Pages: 2579-2585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Alteration of cross-linking selectivity with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects2010
- Author(s)
  S. Imoto, T. Hori, S. Hagihara, Y. Taniguchi, S. Sasaki, F. Nagatsugi
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 20 Pages: 6121-6124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Alteration of cross-linking selectivity with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects2010
- Author(s)
  Imoto, S.; Hori, T.; Hagihara, S.; Taniguchi, Y.; Sasaki, S.; Nagatsugi, F
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 20 Pages: 6121-6124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Design and Synthesis of the Novel cross-linking Agent2009
- Author(s)
  S.Kusano, K.Hattori, S.Imoto, F.Nagatsugi
- Journal Title
  
  Nucleic Acids Symp.Ser 53
  
  Pages: 169-170
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
- Author(s)
  M. M. Ali, S. Imoto, Y. Li , S. Sasaki and F. Nagatsugi
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 17 Pages: 2859-2863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
- Author(s)
  Md. M. Ali b, S. Imoto, Y. Li S. Sasaki F. Nagatsugi
- Journal Title
  
  Bioorg. Med. Chem 17(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021004
[Journal Article] Formation of Highly Selective and Efficient Interstrand Cross-Linking to Thymine Without Photo-Irradiation2009
- Author(s)
  Hattori, K. ; Hirohama, T. ; Imoto, S. ; Kusano, S. ; Nagatsugi, F.
- Journal Title
  
  Chem.Comm. 42
  
  Pages: 6463-6465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
- Author(s)
  M.M.Ali, S.Imoto, Y.Li, S.Sasaki, F.Nagatsugi
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 2859-2863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
- Author(s)
  Md. M. Ali b, S. Imoto, Y. Li S. Sasaki F. Nagatsugi
- Journal Title
  
  Bioorg. Med. Chem. 17(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] Formation of highly selective and efficient interstrand cross-linking to thymine without photo-irradiation2009
- Author(s)
  K. Hattori, T. Hirohama, S. Imoto, S. Kusano, F. Nagatsugi
- Journal Title
  
  Chem. Commun
  
  Volume: 42 Pages: 6463-6465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Journal Article] Synthesis of the Peptide Nucleic Acid(PNA)Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
- Author(s)
  Imoto S., Shimotazawa A., Goto M., Hirohama T., Nagatsugi F.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 391-392
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] New Methodology to Search for DNA Binding Ligands Basedon Duplex DNA-Templated Click Chemistry2008
- Author(s)
  S. Imoto, T. Hirohama, F. Nagatsugi
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 381-382
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] Synthesis and Evaluation of the Peptide Nucleic Acids (PNAs) Incorporating Reactive Artificial Molecules2008
- Author(s)
  S. Imoto, M. Goto, T. Hirohama, F. Nagatsugi
- Journal Title
  
  Collection symposium series (2008) 10
  
  Pages: 414-416
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] DNA Templated Click Chemistry for Creation of Novel DNA Binding Molecules2008
- Author(s)
  Imoto S., Hirohama T., Nagatsugi F.
- Journal Title
  
  Bioorg. Chem. Lett. 18
  
  Pages: 5660-5663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] Synthesis of the Peptide Nucleic Acid (PNA) Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
- Author(s)
  S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 391-392
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] DNA Templated Click Chemistry for Creation of Novel DNA Binding Molecules2008
- Author(s)
  S. Imoto, T. Hirohama, F. Nagatsugi
- Journal Title
  
  Bioorg. Med. Chem. Lett. 18
  
  Pages: 5660-5663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] Synthesis and Evaluation of the Peptide Nucleic Acids (PNAs) Incorp orating Reactive Artificial Molecules2008
- Author(s)
  S. Imoto, M.Goto, T. Hirohama , F. Nagatsugi
- Journal Title
  
  Collection symposium series(2008) 10
  
  Pages: 414-416
- Data Source
  KAKENHI-PROJECT-19021004
[Journal Article] DNA Templated Click Chemistry for Creation of Novel DNABinding Molecules2008
- Author(s)
  S. Imoto, T. Hirohama, F. Nagatsugi
- Journal Title
  
  Bioorg. Med. Chem. Lett 18
  
  Pages: 5660-5663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021004
[Journal Article] Synthesis of the Peptide Nucleic Acid (PNA) Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
- Author(s)
  S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
- Journal Title
  
  Nucleic Acids Symp. Ser 52
  
  Pages: 391-392
- Data Source
  KAKENHI-PROJECT-19021004
[Journal Article] New Methodology to Search for DNA Binding Ligands Based on Duplex DNA-Templated Click Chemistry2008
- Author(s)
  Imoto S., Hirohama, T., Nagatsugi F.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 381-382
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] New Methodology to Search for DNA Binding Ligands Basedon Duplex DNA-Templated Click Chemistry2008
- Author(s)
  S. Imoto, T. Hirohama, F. Nagatsugi
- Journal Title
  
  Nucleic Acids Symp. Ser 52
  
  Pages: 381-382
- Data Source
  KAKENHI-PROJECT-19021004
[Journal Article] Enzymatic Incorporation of 2-amino-6-Vinylpurine Derivative2007
- Author(s)
  Imoto, S
- Journal Title
  
  Nucleic Acids Symp. Ser. 51
  
  Pages: 357-358
- Data Source
  KAKENHI-PROJECT-19021004
[Journal Article] Enzymatic Incorporation of 2-amino-6-Vinylpurine Derivative2007
- Author(s)
  Imoto, S
- Journal Title
  
  Nucleic Acids Symp. Ser. 51
  
  Pages: 357-358
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] Enzymatic Incorporation of 2-amino-6-Vinylpurine Derivative2007
- Author(s)
  Imoto, S.; Ali, M. M.; Li, Y.; Sasaki, S.; Nagatsugi, F.
- Journal Title
  
  Nucleic Acids Symp. Ser. 51
  
  Pages: 357-358
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] Efficient Synthesis of 6-Substituted Purine Derivatives Using Pd-Catalyzed Cross-Coupling Reactions with 2'-Deoxyguanosine O^6-Tosylate2007
- Author(s)
  Nagatsugi F.; Ogata, Y ; Imoto, S.; Sasaki, S.
- Journal Title
  
  Heterocycles 73
  
  Pages: 493-501
- NAID
  40015763816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19350079
[Journal Article] Production of truncated protein by the crosslink formation of mRNA with 2'-OMe oligoribonucleotide containing 2-amino-6-vinylpurine
- Author(s)
  Hagihara, S., Kusano, S., Lin, W. C., Chao, X. G., Hori, T., Imoto, S., Nagatsugi, F.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350086
[Patent] sj2001UU2020
- Inventor(s)
  西弘二、山崎啓之、井本修平、小田切優樹、別府拓豪
- Industrial Property Rights Holder
  西弘二、山崎啓之、井本修平、小田切優樹、別府拓豪
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-010513
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導メカニズムの解明2021
- Author(s)
  別府拓豪、西弘二、井本修平、小田切優樹、山崎啓之
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞におけるニトロ化フェニル酪酸のオートファジー阻害効果2021
- Author(s)
  別府拓豪、西弘二、井本修平、異島　優、月川　健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2021
- Author(s)
  別府拓豪、西弘二、井本修平、異島　優、月川　健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞におけるニトロ化フェニル酪酸の細胞死誘導メカニズムの解明と抗腫瘍効果の評価2021
- Author(s)
  別府拓豪、西弘二、井本修平、異島　優、月川　健士、小田切優樹、山崎啓之
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2020
- Author(s)
  別府拓豪、西弘二、井本修平、小田切優樹、山崎啓之
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2020
- Author(s)
  別府拓豪、西弘二、井本修平、小田切優樹、山崎啓之
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] 6-ビニルプリンによるシトシンへの極めて早い架橋反応2012
- Author(s)
  井本修平、千國友子、永次史、寒水壽朗、國枝武久
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 反応性核酸誘導体を用いたウイルス複製制御を目指した創薬研究2012
- Author(s)
  岩本直生、草野修平、萩原伸也、佐々木要、河治久実、児玉栄一、井本修平、永次史
- Organizer
  第12回多元物質科学研究所研究発表会
- Place of Presentation
  東北大学、仙台
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 架橋反応性核酸を用いた効率的蛋白質発現阻害2012
- Author(s)
  永次史、萩原伸也、草野修平、井本修平
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 6-ビニルプリンによるシトシンへの極めて速いDNA架橋反応2012
- Author(s)
  井本修平、永次史、千國友子、寒水壽朗、國枝武久
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、札幌
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 架橋反応性核酸を用いた効率的蛋白質発現阻害2012
- Author(s)
  永次史、萩原伸也、草野修平、井本修平
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、北海道
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 6-ビニルプリンによるシトシンへの極めて早いDNA架橋反応2012
- Author(s)
  井本修平、永次史、千国友子、寒水壽朗、國枝武久
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、北海道
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 架橋反応性核酸を用いた効率的蛋白質発現阻害2012
- Author(s)
  永次史、萩原伸也、草野修平、井本修平
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、札幌
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 2'-OMe RNA containing 2-amino-6-vinylpurine as a potent gene regulator2011
- Author(s)
  Shinya Hagihara, Shuhei Imoto, Xiau-guang Chao, Tsuneaki Hori, Shuhei Kusano, Fumi Nagatsugi
- Organizer
  第３８回国際核酸化学シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] グアニン6位酸素との架橋反応を目指した人工核酸塩基の開発2011
- Author(s)
  井本修平、千國友子、永次史、寒水壽朗、國枝武久
- Organizer
  第２８回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 細胞内遺伝子発現制御に向けた架橋性核酸の開発2011
- Author(s)
  萩原伸也、井本修平、堀常晃、X. Chao、永次史
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学、神奈川県
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 核酸医薬を目指したチミン選択的クロスリンク剤の開発2011
- Author(s)
  永次史、井本修平、萩原伸也、堀常晃、Cho Xio. Guang
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡大学、静岡県
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Evaluation of the Antisense Effects Using the Reactive Oligonucleotides with High Selectivity to the Target Base2011
- Author(s)
  Fumi Nagatsugi, Tuneaki Hori, Shuhei Kusano, Shuhei Imoto, Shinya Hagihara, Chao Xiao-Guang
- Organizer
  8th AFMC International Medicinal Chemistry Symposium "Frontier of Medicinal Science
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] グアニン6位酸素との架橋反応を目指した人工核酸塩基の開発2011
- Author(s)
  井本修平、千國友子、永次史、寒水壽朗、國枝武久
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学、福岡
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] グアニン6位酸素との架橋反応を目指した人工核酸塩基の開発2011
- Author(s)
  井本修平、千國友子、永次史、寒冰壽朗、國枝武久
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-23659060
[Presentation] 新規ピリミジン誘導体を導入したオリゴ核酸の合成と架橋反応評価2011
- Author(s)
  井本修平、永次史、寒水壽朗、國枝武久
- Organizer
  第41回複素環化合物討論会崇城大学市民ホール
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] Evaluation of the Antisense Effects Using the Reactive Oligonucleotides with High Selectivity to the Target Base2011
- Author(s)
  F.Nagatsugi, T.Hori, S.Kusano, S.Imoto, S.Hagihara, C.H.Guang
- Organizer
  AFMC International Medicinal Chemistry Symposium "Frontier of Medicinal Science
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 新規ピリミジン誘導体を導入したオリゴ核酸の合成と架橋反応評価2011
- Author(s)
  井本修平、永次史、寒水壽朗、國枝武久
- Organizer
  第４１回複素環化学討論会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 架橋性オリゴ核酸による遺伝子発現制御2011
- Author(s)
  萩原伸也、井本修平、堀常晃、鈔暁光、永次史
- Organizer
  第6回日本ケミカルバイオロジー年会
- Place of Presentation
  東京工業大学大岡山キャンパス、東京都
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 架橋性オリゴ核酸による遺伝子発現制御2011
- Author(s)
  萩原伸也、井本修平、堀常晃、ChaoXiao-guang、永次史
- Organizer
  第6回日本ケミカルバイオロジー学会年会東京工業大学大岡山キャンパス
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] Evaluation of the Antisense Effects Using the Reactive Oligonucleotides with High Selectivity to the Target Base2011
- Author(s)
  F. Nagatsugi, T. Hori, S. Kusano, S. Imoto, S. Hagihara, C. H. Guang
- Organizer
  8th AFMC International Medicinal Chemistry Symposium"Frontier of Medicinal Science"
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 新規ピリミジン誘導体を導入したオリコ核酸の合成と架橋反応評価2011
- Author(s)
  井本修平、永次史、寒冰壽朗、國技武久
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23659060
[Presentation] Fumi Nagatsugi"2'-OMe RNA containing 2-amino-6-vinylpurine as a potent gene regulator2011
- Author(s)
  Shinya Hagihara, Shuhei Imoto, Chao Xiao-guang, Tuneaki Hori, Shuhei Kusano
- Organizer
  The 38th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  北海道大学、札幌
- Data Source
  KAKENHI-PROJECT-23790146
[Presentation] 2'-OMe RNA containing 2-amino-6-vinylpurine as a potent gene regulator2011
- Author(s)
  S. Hagihara, S. Imoto, C. X. Guang, S. Kusano, F. Nagatsugi
- Organizer
  The 38th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Crosslink forming oligonucleotide that enhances translation in cells2010
- Author(s)
  S. Hagihara, W.-C. Lin, S. Imoto, T. Hori, F. Nagatsugi
- Organizer
  The 37th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Hamagin Hall"VIA MARE", Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] チミジンを標的とした新規クロスリンク剤の合成と評価2010
- Author(s)
  草野修平・服部恵一・井本修平・永次史
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学本部キャンパス(大阪)
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] チミジンを標的とした新規クロスリンク剤の合成と評価2010
- Author(s)
  草野修平、服部恵一、井本修平、永次史
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学本部キャンパス、大阪府
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] チミンとの架橋反応性を有する新規人工核酸の開発2010
- Author(s)
  井本修平、服部恵一、草野修平、廣濱智哉、萩原伸也、永次史
- Organizer
  第5回日本ケミカルバイオロジー年会
- Place of Presentation
  慶應義塾大学日吉キャンパス、神奈川県
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 反応性核酸を導入した2'-OMeオリゴRNAを用いたアンチセンス効果及びmiRNAの阻害2010
- Author(s)
  永次史、萩原伸也、堀常晃、井本修平
- Organizer
  第20回アンチセンスシンポジウム
- Place of Presentation
  甲南大学ポートアイランドキャンパス
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the Effective Cross-linking Reaction to Target Gene2010
- Author(s)
  F.Nagatsugi, T.Hori, S.Kusano, S.Imoto, S.Hagihara
- Organizer
  Pacifichem 2010
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Cross-linking reactions with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects2010
- Author(s)
  S. Imoto, T. Hori, C. X. Guang, S. Hagihara, Y. Taniguchi, S. Sasaki., F. Nagatsugi
- Organizer
  The 37th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Hamagin Hall"VIA MARE", Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Crosslink forming oligonucleotide that enhances translation in cells (The 37th International Symposium on Nucleic Acids Chemistry2010
- Author(s)
  S.Hagihara, W.-C.Lin, S.Imoto, T.Hori, F.Nagatsugi
- Organizer
  The 37th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Hamagin Hall "VIA MARE", Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] チミンとの架橋反応性を有する新規人工核酸の開発2010
- Author(s)
  井本修平、服部恵一、草野修平、廣濱智哉、萩原伸也、永次史
- Organizer
  第5回日本ケミカルバイオロジー年会
- Place of Presentation
  慶應義塾大学日吉キャンパス協生館
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 2本鎖形成により活性化されるクロスリンク反応の開発2010
- Author(s)
  永次史、井本修平、堀常晃、萩原伸也、谷口陽祐、佐々木茂貴
- Organizer
  第59回高分子討論会
- Place of Presentation
  北海道大学高等教育機能開発総合センター
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 2本鎖形成により活性化されるクロスリンク反応の開発2010
- Author(s)
  永次史、井本修平、堀常晃、萩原伸也、谷口陽祐、佐々木茂貴
- Organizer
  第59回高分子討論会
- Place of Presentation
  北海道大学高等教育機能開発総合センター、北海道
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 新規反応性核酸の開発及びmiRNA阻害に向けた検討2010
- Author(s)
  永次史、堀常晃、井本修平、草野修平、萩原伸也
- Organizer
  第10回遺伝子デリバリー研究会シンポジウム
- Place of Presentation
  北海道大学学術交流会館、北海道
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the effective cross-linking reaction to target gene2010
- Author(s)
  F. Nagatsugi., T. Hori, S. Kusano, S. Imoto, S. Hagihara
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 架橋性核酸を用いた遺伝子発現制御2010
- Author(s)
  萩原伸也、井本修平、堀常晃、永次史
- Organizer
  第10回多元物質科学研究所研究発表会
- Place of Presentation
  東北大学片平キャンパス・さくらホール仙台
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Cross-linking Reactions with the 2'-OMe Analogue of 2-Amino-6-Vinylpurine and Evaluation of Antisense Effects2010
- Author(s)
  S.Imoto, T.Hori, C.X.Guang, S.Hagihara, Y.Taniguchi, S.Sasaki, F.Nagatsug
- Organizer
  The 37th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Hamagin Hall "VIA MARE", Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] チミジン選択的クロスリンク剤の開発2010
- Author(s)
  永次史、服部恵一、廣濱智哉、草野修平、井本修平
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山大学津島キャンパス他(岡山)
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 反応性核酸を導入した2'-OMeオリゴRNAを用いたアンチセンス効果及びmiRNAの阻害2010
- Author(s)
  永次史、萩原伸也、堀常晃、井本修平
- Organizer
  第20回アンチセンスシンポジウム
- Place of Presentation
  甲南大学ポートアイランドキャンパス、兵庫県
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the cross-linking reactions to thymine with high selectivity2010
- Author(s)
  S. Imoto, T. Hori, K. Hattori, S. Kusano, S. Hagihara, Y. Taniguchi, S. Sasaki, F. Nagatsugi
- Organizer
  IRT 2010-XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 新規反応性核酸の開発及びmiRNA阻害に向けた検討2010
- Author(s)
  永次史、堀常晃、井本修平、草野修平、萩原伸也
- Organizer
  第10回遺伝子デリバリー研究会シンポジウム
- Place of Presentation
  北海道大学学術交流会館
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the Novel Cross-linking Agent with High Selectivity to Thymine2009
- Author(s)
  F.Nagatsugi, K.Hattori, T.Hirohama, S.Kusano, S.Imoto
- Organizer
  Joint Symposium of the 5^<th> Annual Meeting of the Oligonucleotide Therapeutics Society and the 19^<th> Antisense Symposium
- Place of Presentation
  Kyushu University Hospital Campus(福岡)
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the novel cross-linking agent with high selectivity to thymine2009
- Author(s)
  F. Nagatsugi, K. Hattori, T. Hirohama, S. Kusano, S. Imoto
- Organizer
  Joint Symposium of the 5^<th> Annual Meeting of the Oligonucleotide Therapeutics Society and the 19^<th> Antisense Symposium
- Place of Presentation
  Centennial Hall, Kyushu University Hospital Campus Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the novel cross-linking reaction to thymine with high selectivity2009
- Author(s)
  F. Nagatsugi, T. Hirohama, S. Kusano, Hattori, S. Imoto
- Organizer
  The 4th International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  Convention Center, Chulabhorn Research Institute, Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Design and synthesis of the novel cross-linking agent2009
- Author(s)
  S. Kusano, K. Hattori, S. Imoto, F. Nagatsugi
- Organizer
  35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Takayama, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the Novel Cross-linking Reaction to Thymine with High Selectivity2009
- Author(s)
  F.Nagatsugi, T.Hirohama, S.Kusano, K.Hattori, S.Imoto
- Organizer
  The 4th International Conference on Cutting-Edge Organic Chemistry in Asia, Convention Center, 2009/11/29-12/3)
- Place of Presentation
  Chulabhorn Research Institue、Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 2本鎖DNA上におけるクリックケミストリーを応用したDNA結合分子探索手法の開発2009
- Author(s)
  永次史、廣濱智哉、井本修平
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸市産業進行センター、兵庫県
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 2本鎖DNA上におけるクリックケミストリーを応用したDNA結合分子探索手法の開発2009
- Author(s)
  永次史、廣濱智哉、井本修平
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸市産業進行センター神戸
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the novel cross-linking reagents to react to the target genes with high selectivity2009
- Author(s)
  F. Nagatsugi, T. Hirohama, S. Kusano, K. Hattori, S. Imoto
- Organizer
  2^<nd> Switzerland-Japan Biomolecular Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] チミジン選択的クロスリンク剤の開発2009
- Author(s)
  草野修平、服部恵一、井本修平、永次史
- Organizer
  第9回多元物質科学研究所研究発表会
- Place of Presentation
  東北大学片平キャンパス・さくらホール(仙台)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 反応性核酸を含むペプチド核酸(PNA)の合成と機能評価2009
- Author(s)
  下田沢梓, 井本修平, 廣濱智哉, 後藤真, 永次史
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  東京
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] 2'修飾型反応性核酸の合成2009
- Author(s)
  堀常晃、井本修平、萩原伸也、永次史
- Organizer
  第9回多元物質科学研究所研究発表会
- Place of Presentation
  東北大学片平キャンパス・さくらホール(仙台)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] Development of the Novel Cross-linking Reagents to React to the Target Genes with High Selectivity2009
- Author(s)
  F.Nagatsugi, T.Hirohama, S.Kusano, K.Hattori, S.Imoto
- Organizer
  2^<nd> Switzerland-Japan Biomolecular Chemistry Symposium
- Place of Presentation
  東京大学駒場リサーチキャンパス・コンベンションホール(東京)
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] RNA選択的クロスリンク剤の開発2009
- Author(s)
  堀常晃, 井本修平, 萩原伸也, 永次史
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  東京
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] RNA選択的クロスリンク剤の開発2009
- Author(s)
  堀常晃, 井本修平, 萩原伸也, 永次史
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  東京
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] 反応性核酸を含むペプチド核酸(PNA)の合成と機能評価2009
- Author(s)
  下田沢梓, 井本修平, 廣濱智哉, 後藤真, 永次史
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  東京
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Design and Synthesis of the Novel cross-linking Agent, (35th Intemational Symposium on Nucleic Acids Chemistry2009
- Author(s)
  S.Kusano, K.Hattori, S.Imoto, F.Nagatsugi
- Organizer
  35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  高山市民文化会館(高山)
- Data Source
  KAKENHI-PROJECT-21350086
[Presentation] 誘起反応性クロスリンク核酸を用いた遺伝子配列特異的な薬物放出システムの開発2008
- Author(s)
  永次史, 中山静香, 志茂祐輔, 井本修平, 佐々木茂貴
- Organizer
  第3回ケミカルバイオロジー研究会
- Place of Presentation
  東京
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] クリックケミストリーを応用した新規DNA結合分子探索手法の開発2008
- Author(s)
  井本修平
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  東京
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] 誘起反応性クロスリンク核酸を用いた遺伝子配列特異的な薬物放出システムの開発2008
- Author(s)
  永次史, 中山静香, 志茂祐輔, 井本修平, 佐々木茂貴
- Organizer
  第3回ケミカルバイオロジー研究会
- Place of Presentation
  東京
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Synthesis of the Peptide Nucleic Acid (PNA) Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
- Author(s)
  S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
- Organizer
  Joint Symposium of 18th International Roundtabl e on Nucleosides, Nucleotides and Nucleic Acids (IRTXVIII) and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  京都
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] グアニンを標的とした新規クロスリンク剤の設計と合成2008
- Author(s)
  服部恵一, 井本修平, 永次史
- Organizer
  第34回反応と合成の進歩シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] RNA型クロスリンク剤の合成とその機能評価2008
- Author(s)
  永次史, 堀常晃, 井本修平, 萩原伸也
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜
- Year and Date
  2008-11-18
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Synthesis and Evaluation of the Peptide Nucleic Acids (PNAs) Ihcorporating Reactive Artificial Molecules2008
- Author(s)
  S. Imoto, M. Goto, T. Hiroha ma, F. Nagatsugi
- Organizer
  XIV Symposium on Chemistry of Nucleic Acid Components
- Place of Presentation
  Czech Republic
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] RNA型クロスリンク剤の合成とその機能評価2008
- Author(s)
  永次史, 堀常晃, 井本修平, 萩原伸也
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜
- Year and Date
  2008-11-18
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] 応性ペプチド核酸の合成と機能評価2008
- Author(s)
  下田沢梓, 井本修平, 廣濱智哉, 後藤真, 永次史
- Organizer
  第20回生体機能関連化学若手の会
- Place of Presentation
  白石
- Year and Date
  2008-08-10
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] 応性ペプチド核酸の合成と機能評価2008
- Author(s)
  下田沢梓, 井本修平, 廣濱智哉, 後藤真, 永次史
- Organizer
  第20回生体機能関連化学若手の会
- Place of Presentation
  白石
- Year and Date
  2008-08-10
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] Synthesis of the Peptide Nucleic Acid (PNA) Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
- Author(s)
  S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids (IRTXVIII) and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  京都
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Synthesis and Evaluation of the Peptide Nucleic Acids(PNAs)Incorporating Reactive Artificial Molecules, XIV Symposium on Chemistry of Nucleic Acid Components2008
- Author(s)
  S. Imoto, M. Goto, T. Hirohama, F. Nagatsugi
- Organizer
  Czesky Krumlov
- Place of Presentation
  Czech Republic
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] グアニンを標的とした新規クロスリンク剤の設計と合成2008
- Author(s)
  服部恵一, 井本修平, 永次史
- Organizer
  第34回反応と合成の進歩シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] Development of New DNA Binding Ligand Based on duplex DNA Templated Click Chemistry, Joint Symposium of 18th International Roundtable on Nucleosides2008
- Author(s)
  T. Hirohama, S. Imoto, F. Nagatsugi
- Organizer
  Nucleotides and Nucleic Acids(IRTXVIII)and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Synthesis of the Peptide Nucleic Acid(PNA)Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
- Author(s)
  S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids(IRTXVIII)and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Development of New DNA Binding Ligand Based on duplex DNA Templated Click Chemistry2008
- Author(s)
  S. Imoto, T. Hirohama, F. Nagatsugi
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids (IRTXVIII) and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  京都
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Development of New DNA Binding Ligand Based on duplex DNA Templated Click Chemistry2008
- Author(s)
  S. Imoto, T. Hirohama, F. Nagatsugi
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids (IRTXVIII) and 35 th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  京都
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] Synthesis and Evaluation of the Peptide Nucleic Acids (PNAs) Incorporating Reactive Artificial Molecules2008
- Author(s)
  S. Imoto, M. Goto, T. Hirohama, F. Nagatsugi
- Organizer
  XIV Symposium on Chemistry of Nucleic Acid Components
- Place of Presentation
  Czech Republic
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] クリックケミストリーを応用した新規DNA結合分子探索手法の開発2008
- Author(s)
  井本修平
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Enzymatic Incorporation of 2-amino-6-Vinylpurine Derivative2007
- Author(s)
  Shuhei Imoto
- Organizer
  5th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] Enzymatic Incorporation of 2-amino-6-Vinylpurine Derivative2007
- Author(s)
  Shuhei Imoto
- Organizer
  5th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] DNAを鋳型とするクリックケミストリーを利用した新規DNA結合性ペプチドの開発2007
- Author(s)
  井本修平
- Organizer
  第22回生体機能関連化学シンポジウム
- Place of Presentation
  東北大学・片平さくらホール
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-19021004
[Presentation] Development of the Methodology for Searching New Binding Molecules to highly-Ordered DNA Structure2007
- Author(s)
  F. Nagatsugi, S. Imoto
- Organizer
  The 2^<nd> International Workshop on Approaches to Single-cell Analysis
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] Enzymatic Incorporation of 2-amino-6-Vinylpurine Derivative2007
- Author(s)
  S.Imoto, M. M. Ali, Y. Li, S. Sasaki, F. Nagatsugi
- Organizer
  5^<th> International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19350079
[Presentation] DNAを鋳型とするクリックケミストリーを利用した新規DNA結合性ペプチドの開発2007
- Author(s)
  井本修平
- Organizer
  第22回生体機能関連化学シンポジウム
- Place of Presentation
  東北大学・片平さくらホール
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-19350079

1. NAGATSUGI Fumi (90208025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 88 results
2. Nishi Koji (00398249)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 山崎啓之 (30435143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. HAGIHARA Shinnya (80373348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 27 results
5. 國枝武久 (80012649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 寒水壽朗 (90412733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 異島優 (00457590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 小田切優樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Imoto Shuhei 井本 修平

井本 修平 イモト シュウヘイ

IMOTO Syuhei 井本 修平

IMOTO Shuhei 井本 修平

Research Projects

Research Products

Co-Researchers

Development of NO donors with high albumin affinity for treatment of pancreatic cancer

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Development of albumin-binding nitric oxide donors for treatment of pancreatic cancer

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G:C→A:T変異を誘導する人工核酸ツールの開発

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Development of methodology for site-specific RNA modification using the Reactive OligonucleotidesPrincipal Investigator

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Development of the Functional Molecules for Genome Targeting Chemistry

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細胞内におけるDNA高次構造認識分子の開発

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Application of the Activated Reaction by Hybridization to Target Genes for the Regulation of Gene Expression in Cells

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[Journal Article] Novel nitric oxide donor, nitrated phenylbutyrate, induces cell death of human pancreatic cancer cells and suppresses tumor growth of cancer xenografts2022

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[Journal Article] The Nitrated Form of Nateglinide Induces Apoptosis in Human Pancreatic Cancer Cells Through a Caspase-dependent Mechanism.2022

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[Journal Article] Production of truncated protein by the crosslink formation of mRNA with 2’-OMe oligoribonucleotide containing 2-amino-6-vinylpurine2012

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[Journal Article] Fast DNA Interstrand Cross-linking Reaction by 6-Vinylpurine2012

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[Journal Article] Imoto Induced cross-linking reactions to target genes using modified oligonucleotides2011

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[Journal Article] Induced cross-linking reactions to target genes using modified oligonucleotides2011

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[Journal Article] Alteration of cross-linking selectivity with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects2010

Author(s)

Imoto Shuhei 井本修平

井本修平イモトシュウヘイ

IMOTO Syuhei 井本修平

IMOTO Shuhei 井本修平