Kudo Ko 工藤耕

Researcher Number	20455728
Other IDs
Affiliation (Current)	2025: 弘前大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 弘前大学, 医学研究科, 准教授 2014 – 2024: 弘前大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 54010:Hematology and medical oncology-related / Basic Section 49020:Human pathology-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 遺伝子改変 / 免疫細胞療法 / 抗体依存性細胞傷害 / 細胞療法 / 遺伝子治療 / 小児がん / 免疫療法 / 骨髄病変 / BRAFV600E / BRAFV600E変異 … More / 測定可能残存病変 / 微小残存病変 / BRAF遺伝子 / ランゲルハンス細胞組織球症 / 組織球症 / トランスレーショナルリサーチ / 移植・再生医療 / 免疫学 / 癌 / キメラ受容体 / キメラ型受容体 / 抗体依存性細胞性障害 / T細胞 / 遺伝子改変T細胞療法 / 抗体医療 / 抗体療法 / 抗体依存性細胞障害 … More Except Principal Investigator ダウン症候群 / 組織球症 / GATA1 / 急性巨核芽球性白血病 / TAM / 病態解明 / 診断基準 / バイオマーカー / ランゲルハンス細胞組織球症関連神経変性症 / 神経変性疾患 / ランゲルハンス細胞組織球症 / 分子標的療法 / MYC / CDKN2A / RUNX1 / 骨髄性白血病 / pathology / NTRK / BRAF / ALK / juvenile xanthogranuloma / 免疫染色 / 分子標的 / 急性巨核芽性白血病 / 付加的遺伝子異常 / MYC/E2F経路 Less

骨髄微小残存病変に着目したランゲルハンス細胞組織球症の分子機構解明Principal Investigator
- Principal Investigator
  
  工藤耕
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Understanding of the molecular mechanisms of myeloid leukemia associated with Down syndrome and developing molecular target therapy
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Establishment of new diagnostic criteria for Langerhans cell histiocytosis-associated neurodegeneration and investigation of underlying pathogenesis
- Principal Investigator
  
  坂本謙一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Shiga University of Medical Science
Molecular pathological classification and identification of molecular target in the non-Langerhans cell histiocytosis
- Principal Investigator
  
  Nakazawa Atsuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Saitama Children's Medical Center
Molecular Mechanisms of Bone Marrow Disease in Langerhans cell histiocytosis (LCH)Principal Investigator
- Principal Investigator
  
  Kudo Ko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Clarification of the mechanism of multistep leukemogenesis of acute megakaryoblastic leukemia associated with Down syndrome and development of the molecular targeted therapy
- Principal Investigator
  
  伊藤悦朗
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hirosaki University
Multistep molecular mechanisms for acute megakaryoblastic leukemia in Down syndrome
- Principal Investigator
  
  Ito Etsuro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hirosaki University
Cancer immnotherapy to augment antibody dependent cellular cytotoxicityPrincipal Investigator
- Principal Investigator
  
  Kudo Ko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University
a novel adoptive T cell therapy exerting ADCC for pediatric cancerPrincipal Investigator
- Principal Investigator
  
  Kudo Ko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hirosaki University

All 2024 2023 2022 2021 2020 2019 2018 2016 2014

All Journal Article Presentation Patent

[Journal Article] Juvenile xanthogranuloma manifesting with LCH‐associated neurodegenerative disease‐like radiological findings2024
- Author(s)
  Daifu Tomoo、Umeda Katsutsugu、Yokoyama Atsushi、Yoshida Takeshi、Saida Satoshi、Kato Itaru、Hiramatsu Hidefumi、Kudo Ko、Higuchi Yoshihisa、Takita Junko
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: NA Issue: 7
- DOI
  10.1002/pbc.31043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07813
[Journal Article] Antileukemic effect of azacitidine, a DNA methyltransferase inhibitor, on cell lines of myeloid leukemia associated with Down syndrome2024
- Author(s)
  Tanaka Tatsuhiko、Kudo Ko、Kanezaki Rika、Yuzawa Kentaro、Toki Tsutomu、Okuse Ryo、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Terui Kiminori、Ito Etsuro
- Journal Title
  
  Experimental Hematology
  
  Volume: 132 Pages: 104179-104179
- DOI
  10.1016/j.exphem.2024.104179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Transient erythroblastopenia due to a GATA1 variant in an infant female2023
- Author(s)
  Yamashita Motoi、Tomoda Takahiro、Mizuo Ami、Isoda Takeshi、Egawa Makiko、Yoshida Masayuki、Toki Tsutomu、Kudo Ko、Terui Kiminori、Ito Etsuro、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 71 Issue: 3
- DOI
  10.1002/pbc.30834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Detection of BRAF V600E mutation in radiological Langerhans cell histiocytosis-associated neurodegenerative disease using droplet digital PCR analysis.2023
- Author(s)
  Shimizu S, Sakamoto K, Kudo K, Morimoto A, Shioda Y.
- Journal Title
  
  Int J Hematol.
  
  Volume: 118 Issue: 1 Pages: 119-124
- DOI
  10.1007/s12185-023-03588-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07851, KAKENHI-PROJECT-21K07813
[Journal Article] Early chemotherapeutic intervention to avoid thyroidectomy in pediatric Langerhans cell histiocytosis with thyroid involvement accompanying tracheal stenosis: a report of two cases2023
- Author(s)
  Aoyama S、Fukuoka K、Kubota H、Narita K、Kudo K、Mitani Y、Oshima K、Mori M、Arakawa Y、Ichimura K、Terui K、Tanami Y、Kawashima H、Nakazawa A、Niitsu T、Takahashi Y、Koh K
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 1 Pages: 99-103
- DOI
  10.1007/s12185-023-03662-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06938, KAKENHI-PROJECT-21K07813
[Journal Article] Optimal timing of liver transplantation for liver cirrhosis caused by sclerosing cholangitis in a patient with Langerhans cell histiocytosis: a case report2023
- Author(s)
  Watakabe Mai、Fukuoka Kohei、Ihara Yoshiyuki、Hara Tomoko、Kudo Ko、Tamura Megumi、Ichimura Kayoko、Tanami Yutaka、Kawashima Hiroshi、Iwama Itaru、Nakazawa Atsuko、Mizuta Koichi、Koh Katsuyoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 5 Pages: 759-764
- DOI
  10.1007/s12185-022-03500-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07813
[Journal Article] Intensification of treatment with vinca alkaloid does not improve outcomes in pediatric patients with Langerhans cell histiocytosis: results from the JPLSG LCH-12 study2023
- Author(s)
  Morimoto A、Shioda Y、Kudo K、Kanegane H、Imamura T、Koh K、Kosaka Y、Yuza Y、Nakazawa A、Saito A M.、Watanabe T、Nakazawa Y
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 1 Pages: 107-118
- DOI
  10.1007/s12185-023-03568-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06938
[Journal Article] Dyserythropoietic anaemia with an intronic GATA1 splicing mutation in patients suspected to have Diamond‐Blackfan anaemia2022
- Author(s)
  Kobayashi Akie、Ohtaka Ryusei、Toki Tsutomu、Hara Junichi、Muramatsu Hideki、Kanezaki Rika、Takahashi Yuka、Sato Tomohiko、Kamio Takuya、Kudo Ko、Sasaki Shinya、Yoshida Taro、Utsugisawa Taiju、Kanno Hitoshi、Yoshida Kenichi、Nannya Yasuhito、Takahashi Yoshiyuki、Kojima Seiji、Miyano Satoru、Terui Kiminori、et al.
- Journal Title
  
  eJHaem
  
  Volume: 3 Issue: 1 Pages: 163-167
- DOI
  10.1002/jha2.374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome-related myeloid disorders2022
- Author(s)
  Kanezaki Rika、Toki Tsutomu、Terui Kiminori、Sato Tomohiko、Kobayashi Akie、Kudo Ko、Kamio Takuya、Sasaki Shinya、Kawaguchi Koji、Watanabe Kenichiro、Ito Etsuro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20587-20587
- DOI
  10.1038/s41598-022-25046-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07790, KAKENHI-PROJECT-23K21429
[Journal Article] Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report2022
- Author(s)
  Kudo Ko、Kubota Yasuo、Toki Tsutomu、Kanezaki Rika、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Sasaki Shinya、Shiba Norio、Tomizawa Daisuke、Adachi Souichi、Yoshida Kenichi、Ogawa Seishi、Seki Masafumi、Takita Junko、Ito Etsuro、Terui Kiminori
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 10 Pages: 3162-3166
- DOI
  10.1182/bloodadvances.2021006383
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-23K21429
[Journal Article] BRAFV600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.2022
- Author(s)
  Ko Kudo, Tsutomu Toki, Rika Kanezaki, and Etsuro Ito
- Journal Title
  
  Haematologica
  
  Volume: epub ahead Issue: 7 Pages: 000-000
- DOI
  10.3324/haematol.2021.279857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-21K06909, KAKENHI-PROJECT-21K06938, KAKENHI-PROJECT-20K07442, KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-23K24297
[Journal Article] Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiopurine Intolerance During the Treatment of Acute Lymphoblastic Leukemia2021
- Author(s)
  Kudo Ko、Sato Tomohiko、Takahashi Yuka、Yuzawa Kentaro、Kobayashi Akie、Kamio Takuya、Sasaki Shinya、Shimada Jun、Otani Katsuki、Tusjimoto Shinichi、Kato Motohiro、Toki Tsutomu、Terui Kiminori、Ito Etsuro
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 43 Issue: 8 Pages: e1173-e1176
- DOI
  10.1097/mph.0000000000002085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-23K21429
[Journal Article] Isolated Bone Recurrence of Medulloblastoma With MYCN Amplification and TP53 Loss: A Case Report2021
- Author(s)
  Takahashi Yuka、Kudo Ko、Ogawa Kaoru、Sato Tomohiko、Kamio Takuya、Sasaki Shinya、Kobayashi Akie、Ito Tatsuya、Yamamoto Tatsuya、Asano Kenichiro、Ohkuma Hiroki、Kurose Akira、Ito Etsuro、Terui Kiminori
- Journal Title
  
  Journal of Pediatric Hematology/Oncology
  
  Volume: 44 Issue: 2 Pages: e593-e596
- DOI
  10.1097/mph.0000000000002234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07813, KAKENHI-PROJECT-23K21429
[Journal Article] Salvage therapy with 2-chlorodeoxyadenosine for refractory and relapsed pediatric Langerhans cell histiocytosis: an updated nationwide survey in Japan2021
- Author(s)
  Taniguchi Maki、Sakamoto Kenichi、Shioda Yoko、Doi Takehiko、Kudo Ko、Fujino Hisanori、Kudo Kazuko、Morimoto Akira
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 3 Pages: 461-463
- DOI
  10.1007/s12185-020-03073-8
- Data Source
  KAKENHI-PROJECT-21K07813
[Journal Article] An international retrospective study for tolerability of 6-mercaptopurine on NUDT15 bi-allelic variants in children with acute lymphoblastic leukemia2021
- Author(s)
  Tanaka Y et al.
- Journal Title
  
  Haematologica
  
  Volume: Epub ahead of print Issue: 7 Pages: 2026-2029
- DOI
  10.3324/haematol.2020.266320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07836, KAKENHI-PROJECT-23K21429
[Journal Article] Epstein-Barr Virus-Negative Granulomatous Disease Due to SAP Deficiency.2021
- Author(s)
  Karasawa T, Kudo K, Tanita K, Takahashi Y, Kanegane H, Terui K.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 41(6) Issue: 6 Pages: 1372-1375
- DOI
  10.1007/s10875-021-01032-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20J10721, KAKENHI-PROJECT-21K07813
[Journal Article] A pediatric case of secondary T-cell acute lymphoblastic leukemia with KMT2A-MAML2 developing after hepatoblastoma treatment2020
- Author(s)
  Takahashi Y, Terui K, Chinen Y, Tandai S, Kudo K, Sasaki S, Tono C, Taki T, Ito E
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 67 Issue: 1
- DOI
  10.1002/pbc.28033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08335, KAKENHI-PROJECT-18H04039
[Journal Article] Clinical, cytogenetic, and molecular analyses of 17 neonates with transient abnormal myelopoiesis and nonconstitutional trisomy 212020
- Author(s)
  Yuzawa Kentaro、Terui Kiminori、Toki Tsutomu、Kanezaki Rika、Kobayashi Akie、Sato Tomohiko、Kamio Takuya、Kudo Ko、Sasaki Shinya、Endo Mikiya、Ozono Shuichi、Nomura Keiko、Ito Etsuro
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 67 Issue: 4
- DOI
  10.1002/pbc.28188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07782, KAKENHI-PROJECT-18K07810
[Journal Article] Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond?Blackfan anemia2020
- Author(s)
  Koyamaishi Shun、Ogawa Seishi et al.
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 56 Issue: 5 Pages: 1013-1020
- DOI
  10.1038/s41409-020-01056-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07868, KAKENHI-PROJECT-23K21429
[Journal Article] Correction: Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia2020
- Author(s)
  Koyamaishi Shun、Ogawa Seishi et al.
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 56 Issue: 5 Pages: 1218-1219
- DOI
  10.1038/s41409-020-01076-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-21K07813
[Journal Article] A Rapid Cytologic Double Staining of Epstein-Barr Virus-encoded Small RNA and Cell Surface Markers for Diagnosis of Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis2019
- Author(s)
  Takahashi N, Kudo K, Tanaka M, Kumagai N, Sato T, Kamio T, Sasaki S, Terui K, Kurose A, Yanagisawa R, Nakazawa Y, Ito E.
- Journal Title
  
  J Pediatr Hematol Oncol.
  
  Volume: - Issue: 8 Pages: 1-1
- DOI
  10.1097/mph.0000000000001647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17K10095
[Journal Article] Comprehensive genetic analyses of relapsed B-cell precursor acute lymphoblastic leukemia in children2019
- Author(s)
  Kaori Kubo, Ko Kudo, Tsutomu Toki, Rika Kanezaki, Fumika Ikeda, Tatsuya Ito, Akie Kobayashi, Tomohiko Sato, Takuya Kamio, Shinya Sasaki, Kiminori Terui, Etsuro Ito
- Journal Title
  
  Hirosaki Medical Journal
  
  Volume: 70 Pages: 13-13
- NAID
  130007757470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10095
[Journal Article] Highly sensitive detection of GATA1 mutations in patients with myeloid leukemia associated with Down syndrome by combining Sanger and targeted next generation sequencing.2019
- Author(s)
  Terui K, Toki T, Taga T, Iwamoto S, Miyamura T, Hasegawa D, Moritake H, Hama A, Nakashima K, Kanezaki R, Kudo K, Saito AM, Horibe K, Adachi S, Tomizawa D, Ito E.
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: - Issue: 3 Pages: 160-167
- DOI
  10.1002/gcc.22816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04110
[Journal Article] Zoledronic acid for relapsed Langerhans cell histiocytosis with isolated skull bone lesion.2019
- Author(s)
  Kudo K, Tanaka T, Kobayashi A, Terui K, Ito E.
- Journal Title
  
  Pediatr Int.
  
  Volume: 61 Issue: 3 Pages: 315-317
- DOI
  10.1111/ped.13774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17K10095
[Journal Article] Two siblings with familial neuroblastoma with distinct clinical phenotypes harboring an ALK germline mutation.2018
- Author(s)
  Kudo K, Ueno H, Sato T, Kubo K, Kanezaki R, Kobayashi A, Kamio T, Sasaki S, Terui K, Kurose A, Yoshida K, Shiozawa Y, Toki T, Ogawa S, Ito E.
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: 57 Issue: 12 Pages: 665-669
- DOI
  10.1002/gcc.22676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04039
[Journal Article] Diplotype analysis of NUDT15 variants and 6-mercaptopurine sensitivity in pediatric lymphoid neoplasms2018
- Author(s)
  Tsujimoto S, Osumi T, Uchiyama M, Shirai R, Moriyama T, Nishii R, Yamada Y, Kudo K, Sekiguchi M, Arakawa Y, Yoshida M, Uchiyama T, Terui K, Ito S, Koh K, Takita J, Ito E, Tomizawa D, Manabe A, Kiyokawa N, Yang JJ, Kato M.
- Journal Title
  
  Leukemia
  
  Volume: 32 Issue: 12 Pages: 2710-2714
- DOI
  10.1038/s41375-018-0190-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10129, KAKENHI-PROJECT-18K07836, KAKENHI-PROJECT-18K19467, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-17H04234
[Patent] Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors2016
- Inventor(s)
  Campana, Dario Kudo, Ko
- Industrial Property Rights Holder
  Campana, Dario Kudo, Ko
- Industrial Property Rights Type
  特許
- Filing Date
  2016-03-31
- Overseas
- Data Source
  KAKENHI-PROJECT-26461561
[Patent] chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors2014
- Inventor(s)
  Dario Campana, Ko Kudo
- Industrial Property Rights Holder
  National University of Singapore
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-17
- Overseas
- Data Source
  KAKENHI-PROJECT-26461561
[Patent] Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors2014
- Inventor(s)
  Campana, Dario Kudo, Ko
- Industrial Property Rights Holder
  Campana, Dario Kudo, Ko
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-17
- Acquisition Date
  2016-04-13
- Overseas
- Data Source
  KAKENHI-PROJECT-26461561
[Presentation] TARGETABLE JUVENILE XANTHOGRANULOMA DETECTED BY IMMUNOHISTOCHEMISTORY-BASED SCREENING SYSTEM2023
- Author(s)
  Kenichi Sakamoto, Kudo Ko, Atsuko Nakazawa, Takako Yoshioka, Akira Morimoto, Yoko Shioda
- Organizer
  Histiocyte Society Annual Meeting 2023
- Data Source
  KAKENHI-PROJECT-21K06938
[Presentation] Usefulness of immunohistochemistry for identification of targetable tyrosine kinase gene mutation in children with juvenile xanthogranuloma.2023
- Author(s)
  Atsuko Nakazawa, Takako Yoshioka, Kenichi Sakamoto, Ko Kudo, Akira Morimoto, Yoko Shioda
- Organizer
  第69回日本病理学会秋期特別総会
- Data Source
  KAKENHI-PROJECT-21K06938
[Presentation] 小児ランゲルハンス細胞組織球症における骨髄血 BRAFV600E 陽性細胞の臨床的意義2022
- Author(s)
  工藤　耕
- Organizer
  日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-21K07813
[Presentation] Immunohistochemistry-based screening for targetable molecules in patients with Juvenile xanthogranuloma.2022
- Author(s)
  Kenichi Sakamoto, Kudo Ko, Atsuko Nakazawa, Takako Yoshioka, Akira Morimoto, Yoko Shioda.
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06938
[Presentation] 小児ランゲルハンス組織球症の骨髄病変におけるBRAFV600E変異2021
- Author(s)
  工藤　耕
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07813
[Presentation] 硬化性胆管炎を合併し生体肝移植を行ったLCHの1例2021
- Author(s)
  渡壁麻依、福岡講平、井原欣幸、原朋子、工藤耕、田波穣、川嶋寛、中澤温子、水田耕一、康勝好
- Organizer
  第63回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06938
[Presentation] 小児のランゲルハンス細胞組織球症における骨髄血中BRAF V600E陽性細胞の意義について2021
- Author(s)
  工藤　耕
- Organizer
  第63回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07813
[Presentation] BRAFV600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis2021
- Author(s)
  工藤　耕
- Organizer
  第37回国際組織球症学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07813
[Presentation] 小児のランゲルハンス細胞組織球症2021
- Author(s)
  工藤　耕
- Organizer
  第63回日本小児血液・がん学会学術集会　教育講演
- Invited
- Data Source
  KAKENHI-PROJECT-21K07813
[Presentation] 2.BRAF V600E-positive precursors as molecular markers of bone marrow involvement in pediatric langerhans cell histiocytosis2019
- Author(s)
  Kudo K
- Organizer
  The 61th American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10095
[Presentation] 小児ランゲルハンス細胞組織球症における骨髄血中BRAF変異陽性細胞の意義についての検討2019
- Author(s)
  工藤耕
- Organizer
  第61回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-17K10095
[Presentation] 3.BRAFV600E-POSITIVE PRECURSORS AS MOLECULAR MARKERS OF BONE MARROW INVOLVEMENT IN PEDIATRIC LANGERHANS CELL HISTIOCYTOSIS.2019
- Author(s)
  Kudo K
- Organizer
  The 35th Annual Meeting of the Histiocyte Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10095
[Presentation] HNRNPH1-MLLT10融合遺伝子を検出した5q- AMLの1例2019
- Author(s)
  工藤耕
- Organizer
  第81回日本血液学会
- Data Source
  KAKENHI-PROJECT-17K10095
[Presentation] BRAFV600E-POSITIVE PRECURSORS AS MOLECULAR MARKERS OF BONE MARROW INVOLVEMENT IN PEDIATRIC LANGERHANS CELL HISTIOCYTOSIS.2019
- Author(s)
  Ko Kudo, Rika Kanezaki, Masaru Imamura, Chihaya Imai, Masahiro Irie, Yoji Sasahara, Kumiko Ando, Harumi Kakuda, Takehiko Doi, Hiroshi Kawaguchi, Kazuko Kudo, Hirokazu Kanegane, Tsutomu Toki, and Etsuro Ito.
- Organizer
  35th Annual Meeting of the Histiocyte Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04039
[Presentation] T Lymphocytes Expressing a CD16 Signaling Receptor Exert Antibody-Dependant Cancer Cell Killing2014
- Author(s)
  工藤　耕
- Organizer
  第76回日本血液学会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-26461561

1. 土岐力 (50195731)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
2. ITO Etsuro (20168339)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. 佐藤知彦 (70587005)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 照井君典 (00333740)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
5. 金崎里香 (60722882)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. 塩田曜子 (30307532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. Nakazawa Atsuko (90227736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 坂本謙一 (20782048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Dario Campana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAGAWA Atsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
11. MORIMOTO Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 滝智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 真部淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kudo Ko 工藤 耕

Research Projects

Research Products

Co-Researchers

骨髄微小残存病変に着目したランゲルハンス細胞組織球症の分子機構解明Principal Investigator

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Understanding of the molecular mechanisms of myeloid leukemia associated with Down syndrome and developing molecular target therapy

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Establishment of new diagnostic criteria for Langerhans cell histiocytosis-associated neurodegeneration and investigation of underlying pathogenesis

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Molecular pathological classification and identification of molecular target in the non-Langerhans cell histiocytosis

Principal Investigator

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Molecular Mechanisms of Bone Marrow Disease in Langerhans cell histiocytosis (LCH)Principal Investigator

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Clarification of the mechanism of multistep leukemogenesis of acute megakaryoblastic leukemia associated with Down syndrome and development of the molecular targeted therapy

Principal Investigator

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Multistep molecular mechanisms for acute megakaryoblastic leukemia in Down syndrome

Principal Investigator

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Cancer immnotherapy to augment antibody dependent cellular cytotoxicityPrincipal Investigator

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a novel adoptive T cell therapy exerting ADCC for pediatric cancerPrincipal Investigator

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[Journal Article] Juvenile xanthogranuloma manifesting with LCH‐associated neurodegenerative disease‐like radiological findings2024

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[Journal Article] Antileukemic effect of azacitidine, a DNA methyltransferase inhibitor, on cell lines of myeloid leukemia associated with Down syndrome2024

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[Journal Article] Transient erythroblastopenia due to a GATA1 variant in an infant female2023

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[Journal Article] Detection of BRAF V600E mutation in radiological Langerhans cell histiocytosis-associated neurodegenerative disease using droplet digital PCR analysis.2023

Author(s)

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[Journal Article] Early chemotherapeutic intervention to avoid thyroidectomy in pediatric Langerhans cell histiocytosis with thyroid involvement accompanying tracheal stenosis: a report of two cases2023

Author(s)

Kudo Ko 工藤耕