Nemoto Yasuhiro 根本泰宏

… Alternative Names

NEMOTO Yasuhiro 根本泰宏

根元泰宏ネモトヤスヒロ

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Researcher Number	20456213
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 大学院医歯学総合研究科, 准教授 2022 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2021 – 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2016 – 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 … More 2012: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教 2010 – 2011: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, GCOE拠点形成特任教員 2008 – 2010: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 特任助教 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Medium-sized Section 53:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator 腸管免疫 / 炎症性腸疾患 / 抗原提示細胞 / アナジー / DNT細胞 / double negative T細胞 / メモリーT細胞 / IL-7 / GLP1R / Adrb1 … More / 神経免疫 / CD4-CD8-T細胞 / 腸管上皮間リンパ球 / 抗原提示 / 腸管粘膜免疫 / γδT細胞 / Double Negative T細胞 / CD4-CD8αβ-T細胞 / 上皮間リンパ球 / クローン病 / 腸管上皮間細胞 / メモリー幹細胞 / 長期培養 / CD4 / CD4+T細胞 / CD4^+T細胞 / CD4^+ T細胞 / 間葉系幹細胞 / 無菌マウス / 腸内細菌 / 骨髄 … More Except Principal Investigator 炎症性腸疾患 / オルガノイド / 上皮間リンパ球 / 腸管免疫 / メモリーT細胞 / 腸管上皮間リンパ球 / 粘膜免疫 / 空間トランスクリプトーム / バイオマーカー / クローン病 / 再生医療 / 腸管上皮間細胞 / イメージング / 小腸腫瘍 / 大腸癌 / IEL / がん免疫 / 腸管腫瘍 / 癌免疫 / アナジー / T細胞 / T-T presentation / photoconversion / intravital microscopy / in vivo live imaging / IL-7R / IL-7 / double negatuve T細胞 / 腸管上皮内リンパ球 / γδT細胞 / Double Negative T細胞 Less

Development of Novel Therapeutic Strategies for Inflammatory Bowel Disease Through the Integration of Tissue Regeneration and Immune Modulation
- Principal Investigator
  
  岡本隆一
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Institute of Science Tokyo
DNT細胞を基点とした-腸管における免疫-神経-内分泌ネットワークの解明Principal Investigator
- Principal Investigator
  
  根本泰宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Institute of Science Tokyo
Investigation of Refractory Mechanisms in Small Intestinal Lesions of Crohn's Disease and Their Application to AI-Assisted Personalized Medicine
- Principal Investigator
  
  河本亜美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Institute of Science Tokyo
炎症性腸疾患病態におけるT-T presentationの役割の解明
- Principal Investigator
  
  齊藤詠子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
疾患／臓器／領域レベルでのアナジー誘導性抗原提示細胞；DNT細胞研究の拡大Principal Investigator
- Principal Investigator
  
  根本泰宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Tokyo Medical and Dental University
Analysis of CD4-CD8alphabeta-TCRalphabeta+ T cells as anergic antigen presenting cellsPrincipal Investigator
- Principal Investigator
  
  Nemoto Yasuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
複合イメージング系による腸管腫瘍ニッチにおけるT細胞動態の可視化
- Principal Investigator
  
  小田柿智之
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
Visualization of the dynamics of colitogenic memory T cells in vivo
- Principal Investigator
  
  Okada Eriko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of unconventional T cells as novel antigen presenting cellsPrincipal Investigator
- Principal Investigator
  
  Nemoto Yasuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Analysis of intestinal CD4-CD8- double negative T cells
- Principal Investigator
  
  OKADA Eriko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
複数の機能的マーカーを用いた炎症性腸疾患における腸炎惹起性メモリー幹細胞の探求Principal Investigator
- Principal Investigator
  
  根本泰宏
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
The functional analysis of IL-7 receptor in colitogenic memory Tcell.
- Principal Investigator
  
  OKADA Eriko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Colitogenic memory T cells are maintained by IL-7-producing cells in bone marrow.Principal Investigator
- Principal Investigator
  
  NEMOTO Yasuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University

All 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] INTESTINE　Vol.162012
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-24590933
[Book] G.I.Research　20巻2012
- Author(s)
  根本泰宏、渡辺守
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24590933
[Book] 臨床免疫・アレルギー科　57巻2012
- Author(s)
  根本泰宏、渡辺守
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24590933
[Book] リンパ学　35巻2012
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Publisher
  日本リンパ学会
- Data Source
  KAKENHI-PROJECT-24590933
[Book] 消化器と免疫　49巻2012
- Author(s)
  根本泰宏
- Publisher
  マイライフ社
- Data Source
  KAKENHI-PROJECT-24590933
[Book] 実験医学増刊号:免疫記憶の制御と疾患治療2011
- Author(s)
  根本泰宏、金井孝典、渡辺守
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22590695
[Book] 消化器と免疫2009
- Author(s)
  根本泰宏、渡辺守, 他
- Publisher
  マイライフ社
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4+ memory T cells.2013
- Author(s)
  Nemoto Y, Nakamura T, Watanabe M et al
- Journal Title
  
  Gut.
  
  Volume: 62 Issue: 8 Pages: 1142-1152
- DOI
  10.1136/gutjnl-2012-302029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506
[Journal Article] T-helper 17 and Interleukin-17-Producing Lymphoid Tissue Inducer-Like T Cells Make Different Contributions to Colitis in Mice.2012
- Author(s)
  Ono Y, Kanai T, Sujino T, Nemoto Y, Kanai Y, Mikami Y, Hayashi A, Matsumoto A, Takaishi H, Ogata H, Matsuoka K, Hisamatsu T, Watanabe M, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 143 Issue: 5 Pages: 1288-1297
- DOI
  10.1053/j.gastro.2012.07.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-22590763, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24659375
[Journal Article] Upregulated IL-7 receptor (alpha) expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis.2011
- Author(s)
  Shinohara T, Nemoto Y Watanabe M, et al.
- Journal Title
  
  J Immunol. 186
  
  Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Upregulated IL-7 receptor (alpha) expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis.2011
- Author(s)
  Shinohara T, Nemoto Y, et al.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 186 Pages: 2623-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590695
[Journal Article] Upregulated IL-7 receptor(alpha)expression on colitogenic memory CD4^+ T cells may participate in the development and persistence of chronic colitis.2011
- Author(s)
  Shinohara T, Nemoto Y, et al.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Luminal CD4+ T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation2011
- Author(s)
  Nemoto Y, Watanabe M
- Journal Title
  
  Gastroenterology
  
  Volume: 141 Issue: 6 Pages: 2130-2139
- DOI
  10.1053/j.gastro.2011.08.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590804, KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777
[Journal Article] IL-2 is positively involved in the development of colitogenic CD4+ IL-7R alpha high memory T cells in chronic colitis.2010
- Author(s)
  Kameyama K, Nemoto Y, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol. 40
  
  Pages: 2423-2436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] IL-2 is positively involved in the development of colitogenic CD4+ IL-7R alpha high memory T cells in chronic colitis.2010
- Author(s)
  Kameyama K, Nemoto Y, et al
- Journal Title
  
  European Journal of Immunology
  
  Volume: 40 Pages: 2423-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590695
[Journal Article] IL-2 is positively involved in the development of colitogenic CD4^+ IL-7Ralpha high memory T cells in chronic colitis.2010
- Author(s)
  Kameyama K, Nemoto Y, et al
- Journal Title
  
  European Journal of Immunology
  
  Volume: 40 Pages: 2423-2436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4^+ memory T cells in chronic colitis.2009
- Author(s)
  Tomita T, Nemoto Y, et al.
- Journal Title
  
  Eur J Immunol. 39
  
  Pages: 2737-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Persistent retention of colitogenic CD4+ memory T cells causes inflammatory bowel diseases to become intractable.2009
- Author(s)
  Kanai T, Nemoto Y, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Dis. 15(Review)
  
  Pages: 926-934
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Long-lived colitogenic CD4^+ memory T cells residing outside the intestine participate in the perpetuation of chronic colitis.2009
- Author(s)
  Nemoto Y, Kanai T, et al.
- Journal Title
  
  J Immunol. 183
  
  Pages: 5059-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Persistent retention of colitogenic CD4^+ memory T cells causes inflammatory bowel diseases to become intractable.2009
- Author(s)
  Kanai T, Nemoto Y, et al.
- Journal Title
  
  Inflamm Bowel Dis 15
  
  Pages: 926-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Long-lived colitogenic CD4+ memory T cells residing outside the intestine participate in the perpetuation of chronic colitis.2009
- Author(s)
  Nemoto Y, Kanai T, Watanabe M, et al.
- Journal Title
  
  J Immunol. 183
  
  Pages: 5059-5068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4+ memory T cells in chronic colitis.2009
- Author(s)
  Tomita T, Nemoto Y, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol. 39
  
  Pages: 2737-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Homeostatic(IL-7)and effector(IL-17)cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease.2009
- Author(s)
  Kanai T, Nemoto Y, et al.
- Journal Title
  
  Curr Opin Gastroenterol 25
  
  Pages: 306-13
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Negative feedback regulation of colitogenic CD4^+T cells by increasedgranulopoiesis.2008
- Author(s)
  Nemoto Y, Kanai T, et al
- Journal Title
  
  Inflamm Bowel Dis. 2008 14
  
  Pages: 1491-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis.2008
- Author(s)
  Nemoto Y, Kanai T, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Dis. 14
  
  Pages: 1491-1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Colitogenic CD4+ effector-memory T cells actively recirculate in chronic colitic mice.2008
- Author(s)
  Tomita T, Nemoto Y, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Dis. 14
  
  Pages: 1630-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Colitogenic CD4^+ effector-memory T cells actively recirculate in chroniccolitic mice.2008
- Author(s)
  Tomita T, Nemoto Y, et al.
- Journal Title
  
  Inflamm Bowel Dis. 14
  
  Pages: 1630-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Persistent retention of colitogenic CD4^+ memory T cells causes inflammatorybowel diseases to become intractable.2008
- Author(s)
  Kanai T, Nemoto Y, et al.
- Journal Title
  
  Inflamm Bowel Dis. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice bymodulating the trafficking of colitogenic CD4^+ T cells in bone marrow.2008
- Author(s)
  Fujii T, Nemoto Y, et al
- Journal Title
  
  Eur J Immunol. 38
  
  Pages: 3290-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion ofcolitogenic CD4^+T cells in chronic colitis.2008
- Author(s)
  Tomita T, Nemoto Y, et al
- Journal Title
  
  J Immunol 180
  
  Pages: 5291-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow.2008
- Author(s)
  Fujii T, Nemoto Y, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 3290-3303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Continuous generation of colitogenic CD4+ T cells in persistent colitis.2008
- Author(s)
  Tomita T, Nemoto Y, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol. 38
  
  Pages: 1264-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4+ T cells in chronic colitis.2008
- Author(s)
  Tomita T, Nemoto Y, Watanabe M, et al.
- Journal Title
  
  J Immunol. 180
  
  Pages: 5291-5299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Continuous generation of colitogenic CD4^+ T cells in persistent colitis.2008
- Author(s)
  Tomita T, Nemoto Y, et al
- Journal Title
  
  Eur J Immunol. 38
  
  Pages: 1264-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Journal Article] Immunosenescent colitogenic CD4^+ T cells convert to regulatory cells andsuppress colitis.2008
- Author(s)
  Totsuka T, Nemoto Y, et al
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1275-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 炎症性腸疾患難治性の要因としての腸炎惹起性メモリーCD4^+ T細胞再循環機構2011
- Author(s)
  根本泰宏
- Organizer
  日本消化器免疫学会総会
- Place of Presentation
  金沢
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] Luminal CD4^+ T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation2011
- Author(s)
  根本泰宏
- Organizer
  ICMI
- Place of Presentation
  Paris
- Year and Date
  2011-07-07
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] 炎症性腸疾患メモリーCD4^+ T細胞の腸管-骨髄循環経路2011
- Author(s)
  根本泰宏
- Organizer
  第35回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] 炎症性腸疾患病原性メモリーCD4^+ T細胞は腸管粘膜から全身血流に再循環する2011
- Author(s)
  根本泰宏
- Organizer
  JDDW2011
- Place of Presentation
  福岡
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] IL-7Rα expression on CD4^+ T cells, but not on other cells is essential for the development of chronic colitis2011
- Author(s)
  根本泰宏
- Organizer
  DDW2011
- Place of Presentation
  シカゴ
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] CD4^+CD45RB^<high>T細胞移入大腸炎マウスの病態における腸内細菌の役割2011
- Author(s)
  根本泰宏
- Organizer
  日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] IL-7-producing mesenchymal stem cells sustain colitogenic memory CD4^+ T cells for the persistence of chronic colitis2010
- Author(s)
  Nemoto T
- Organizer
  DDW 2010(米国消化器病関連週間)
- Place of Presentation
  米国(ニューオリンズ)
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 炎症性腸疾患メモリーCD4+ T細胞は腸内細菌非依存的/IL-7 依存的に維持される2010
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  第47回日本消化器免疫学会総会
- Place of Presentation
  滋賀
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] IL-7-producing mesenchymal stemcells sustain colitogenic memory CD4+ T cells for the persistence of chcolitis2010
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  DDWronic2010
- Place of Presentation
  ニューオリンズ
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] IL-7-producing mesenchymal stromal cells sustaincolito genic memory CD4+ T cells for thepersistence of inflammatory bowel disease2010
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  第14回国際免疫学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] IL-7-producing mesenchymal stem cells sustain colitogenic memory CD4+ Tcells for the persistence of chronic colitis2010
- Author(s)
  Nemoto T
- Organizer
  DDW 2010(米国消化器病関連週間)
- Place of Presentation
  米国(ニューオリンズ)
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] 腸炎惹起性メモリーCD4+ T細胞再循環経路をターゲットとした炎症性腸疾患の治療戦略2010
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  JDDW2011
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 炎症性腸疾患メモリーCD4^+ T細胞は腸内細菌非依存的/IL-7依存的に維持される2010
- Author(s)
  根本泰宏
- Organizer
  日本消化器免疫学会総会
- Place of Presentation
  滋賀
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] IL-7-producing mesenchymal stromal cells sustain colitogenic memory CD4+ Tcells for the persistence of inflammatory bowel disease2010
- Author(s)
  Nemoto T
- Organizer
  国際免疫学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] 腸炎惹起性メモリーCD4^+ T細胞再循環経路をターゲットとした炎症性腸疾患の治療戦略2010
- Author(s)
  根本泰宏
- Organizer
  JDDW 2011(日本消化器病関連週間)
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 炎症性腸疾患メモリーCD4+T細胞は腸内細菌非依存的/IL-7依存的に維持される2010
- Author(s)
  根本泰宏
- Organizer
  日本消化器免疫学会総会
- Place of Presentation
  滋賀
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] IL-7-producing mesenchymal stromal cells sustain colitogenic memory CD4^+T cells for the persistence of inflammatory bowel disease2010
- Author(s)
  Nemoto T
- Organizer
  国際免疫学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 腸炎惹起性メモリーCD4+T細胞再循環経路をターゲットとした炎症性腸疾患の治療戦略2010
- Author(s)
  根本泰宏
- Organizer
  JDDW 2011(日本消化器病関連週間)
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22590695
[Presentation] Long-lived Colitogenic CD4^+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis2009
- Author(s)
  根本泰宏、渡辺守, 他
- Organizer
  DDW 2009(米国消化器病関連週間)
- Place of Presentation
  シカゴ
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] Long-lived Colitogenic CD4+ Memory T Cells can be Maintained Outside the Intestine in the Absence of Commesal Bacteria2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  14thICMI
- Place of Presentation
  ボストン
- Year and Date
  2009-07-07
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] Long-lived Colitogenic CD4^+ Memory T Cells can be Maintained Outside the Intestine in the Absence of Commesal Bacteria.2009
- Author(s)
  根本泰宏、渡辺守, 他
- Organizer
  The 3rd Japan & US Collaboration Conference in Gastroenterology
- Place of Presentation
  東京
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 腸内細菌から直接的自然免疫と抗原刺激を受ける炎症性腸疾患メモリーCD4+T細胞の維持機構2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  JDDW2009
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 炎症性腸疾患治療標的としてのIL-7 高産生細胞の同定2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  第46回消化器免疫学会
- Place of Presentation
  松山
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] Long-lived Colitogenic CD4+ Memory TCells Residing Outside the Intestine Participate in the Perpetuation of ChronicColitis2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  DDW2009
- Place of Presentation
  シカゴ
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 腸内細菌から直接的自然免疫と抗原刺激を受ける炎症性腸疾患メモリーCD4^+T細胞の維持機構2009
- Author(s)
  根本泰宏、渡辺守, 他
- Organizer
  JDDW 2009(日本消化器関連学会週間)
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] Long-lived Colitogenic CD4+ Memory T Cells can be Maintained Outside the Intestine in theAbsence of Commesal Bacteria2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  The 3rd Japan & US Collaboration Conferencein Gastroenterology
- Place of Presentation
  東京
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] Long-lived Colitogenic CD4^+ Memory T Cells can be Maintained Outside the Intestine in the Absence of Commesal Bacteria2009
- Author(s)
  根本泰宏、渡辺守, 他
- Organizer
  14^<th>ICMI(国際粘膜免疫学会)
- Place of Presentation
  ボストン
- Year and Date
  2009-07-07
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 炎症性腸疾患治療標的としてのIL-7高産生細胞の同定2009
- Author(s)
  根本泰宏、渡辺守, 他
- Organizer
  第46回消化器免疫学会
- Place of Presentation
  松山
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] Negative Feedback Regulation of Pathogenic CD4^<+>T Cells by Increased Granulopoiesis2008
- Author(s)
  Nemoto
- Organizer
  DDW
- Place of Presentation
  San Diego
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 腸炎骨髄に存在する腸炎惹起性CD4+メモリー細胞による自然免疫系へのフィードバック機構2008
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  第94回消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-08
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 骨髄における腸炎惹起性メモリーT細胞と顆粒球造血系のクロストーク, ミニシンポジウム2008
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  日本本泰宏第45回消化器免疫学会
- Place of Presentation
  京都
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] IL-7 を標的とした腸炎惹起性メモリーT細胞の制御2008
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  JDDW2008
- Place of Presentation
  東京
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 腸炎骨髄に存在する腸炎惹起性CD4^+メモリー細胞による自然免疫系へのフィードバック機構2008
- Author(s)
  根本泰宏
- Organizer
  消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-08
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] Negative Feedback Regulation of Pathogenic CD4+ T Cells by Increased Granulopoiesis.2008
- Author(s)
  根本泰宏, 金井隆典, 渡辺守, 他
- Organizer
  DDW2008
- Place of Presentation
  San Diego.
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20590736
[Presentation] 炎症性腸疾患難治性の要因としての腸炎惹起性メモリーCD4+T細胞維持機構の解析
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Organizer
  第49回日本消化器免疫学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590933
[Presentation] Colitogenic effector memory CD4+ T cells develop Th1/Th17 mediated interstitial pneumonia independent to intestinal bacterial antigens.
- Author(s)
  Nemoto Y, Watanabe M　et al
- Organizer
  DDW2012
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-24590933
[Presentation] Regeneration of damaged colon epithelium by transplanted colon Lgr5+ stem cells maintained and expanded in vitro.
- Author(s)
  Yui S, Nemoto Y, Watanabe M et al
- Organizer
  第10回幹細胞シンポジウム
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PROJECT-24590933

1. WATANABE Mamoru (10175127)

# of Collaborated Projects: 6 results

# of Collaborated Products: 39 results
2. 岡本隆一 (50451935)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. OKADA Eriko (20376784)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 水谷知裕 (80632588)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 齊藤詠子 (00406456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 森川亮 (60910122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小田柿智之 (70740083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松沢優 (30733844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 藤井悟 (00964751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 河本亜美 (70849124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 竹中健人 (10783368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中村哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nemoto Yasuhiro 根本 泰宏

NEMOTO Yasuhiro 根本 泰宏

根元 泰宏 ネモト ヤスヒロ

Research Projects

Research Products

Co-Researchers

Development of Novel Therapeutic Strategies for Inflammatory Bowel Disease Through the Integration of Tissue Regeneration and Immune Modulation

Principal Investigator

Project Period (FY)

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DNT細胞を基点とした-腸管における免疫-神経-内分泌ネットワークの解明Principal Investigator

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Investigation of Refractory Mechanisms in Small Intestinal Lesions of Crohn's Disease and Their Application to AI-Assisted Personalized Medicine

Principal Investigator

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炎症性腸疾患病態におけるT-T presentationの役割の解明

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疾患／臓器／領域レベルでのアナジー誘導性抗原提示細胞；DNT細胞研究の拡大Principal Investigator

Principal Investigator

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Analysis of CD4-CD8alphabeta-TCRalphabeta+ T cells as anergic antigen presenting cellsPrincipal Investigator

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複合イメージング系による腸管腫瘍ニッチにおけるT細胞動態の可視化

Principal Investigator

Project Period (FY)

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Research Institution

Visualization of the dynamics of colitogenic memory T cells in vivo

Principal Investigator

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Review Section

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Analysis of unconventional T cells as novel antigen presenting cellsPrincipal Investigator

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Analysis of intestinal CD4-CD8- double negative T cells

Principal Investigator

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複数の機能的マーカーを用いた炎症性腸疾患における腸炎惹起性メモリー幹細胞の探求Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The functional analysis of IL-7 receptor in colitogenic memory Tcell.

Principal Investigator

Project Period (FY)

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Research Institution

Colitogenic memory T cells are maintained by IL-7-producing cells in bone marrow.Principal Investigator

Principal Investigator

Nemoto Yasuhiro 根本泰宏

NEMOTO Yasuhiro 根本泰宏

根元泰宏ネモトヤスヒロ

[Book] INTESTINE　Vol.162012

[Book] G.I.Research　20巻2012

[Book] 臨床免疫・アレルギー科　57巻2012

[Book] リンパ学　35巻2012

[Book] 消化器と免疫　49巻2012