Makabe Koki 眞壁幸樹

… Alternative Names

MAKABE Koki 真壁幸樹

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Researcher Number	20508072
Other IDs
Affiliation (Current)	2025: 山形大学, 大学院理工学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 山形大学, 大学院理工学研究科, 教授 2013 – 2022: 山形大学, 大学院理工学研究科, 准教授 2011 – 2015: 山形大学, 理工学研究科, 准教授 2012: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 助教 2012: 山形大学, 大学院・理工学研究科, 准教授 … More 2011: 大学共同利用機関法人自然科学研究機構(共通施設), 岡崎統合バイオサイエンスセンター, 助教 2010: 自然科学研究機構, 岡崎統合バイオサイエンスセンター, 助教 2009: National Institutes of Natural Sciences Okazaki Research Facilities, 岡崎統合バイオサイエンスセンター, 助教 2008 – 2009: National Institutes of Natural Sciences Okazaki Research Facilities, 岡崎統合バイオサイエンスセンター, 助教 Less
Review Section/Research Field	Principal Investigator Biophysics / Basic Section 27040:Biofunction and bioprocess engineering-related / Drug development chemistry Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 35030:Organic functional materials-related / Basic Section 38030:Applied biochemistry-related / Tumor therapeutics / Engineering / Science and Engineering / Biofunction/Bioprocess / Science and Engineering
Keywords	Principal Investigator 蛋白質工学 / アミロイド / βシート / 人工酵素 / アミロイド触媒 / インテイン / 蛋白質ライゲーション / 抗体 / 重鎖抗体 / 二重特異性抗体 … More / 蛋白質トランススプライシング / 抗体工学 / 水素重水素交換 / タンパク質 / 構造揺らぎ / 蛋白質 / GroEL / 水素交換 / シャペロン / タンパク質工学 / 自己組織化 / X線結晶構造解析 / ナノ繊維 / 生物物理 / フォールディング / 蛋白質デザイン … More Except Principal Investigator 蛋白質 / バイオテクノロジー / 分子認識 / 二重特異性抗体 / ナノバイオ / 構造モデリング / クライオ電顕構造解析 / 蛍光標識 / 分子軌道制御 / π共役系 / 蛍光色素 / スルホニルアニリン / 抗真菌 / 耐熱性 / キチナーゼ / 次世代抗体設計 / マルチスケール解析 / 癌 / がん / 抗体 / タンパク質 / 生物機能工学 / 分子シャペロニン / アロステリック転移 / 生体分子 / 分子機械 / 生物物理 / 二次元NMR / 水素交換法 / 構造揺らぎ / シャペロニン / 分子シャペロン / フォールディング Less

New Frontiers in Sulfonylaniline Fluorescent Dyes: Functional Design Based on Structural Control and Transformation
- Principal Investigator
  
  片桐洋史
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 35030:Organic functional materials-related
- Research Institution
  Yamagata University
酸性条件下で耐熱性を示すGH19型キチナーゼの構造解析と抗真菌酵素製剤の開発
- Principal Investigator
  
  矢野成和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Yamagata University
アミロイド触媒型の原始酵素モデルに着想した人工酵素のデザインと応用Principal Investigator
- Principal Investigator
  
  眞壁幸樹 (真壁幸樹)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Yamagata University
高活性二重特異性抗体の創製に資する至適な抗原配置の先端的構造解析による描像
- Principal Investigator
  
  熊谷泉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo University of Agriculture and Technology
Consideration on the high activation mechanism of bispecific antibodies by multi-scale analysis for the design of next-generation antibodies
- Principal Investigator
  
  Kumagai Izumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo University of Agriculture and Technology
Innovative cancer-specific structural conversion design into high functional small bispecific antibodies
- Principal Investigator
  
  Asano Ryutaro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Tokyo University of Agriculture and Technology
Construction of bispecific antibodies from the camelid antibody VHHs via in-cell protein trans-splicingPrincipal Investigator
- Principal Investigator
  
  Makabe Koki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Yamagata University
Bio-design for interface molecules in nano scale
- Principal Investigator
  
  KUMAGAI IZUMI
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Engineering
- Research Institution
  Tohoku University
Structural fluctuations of protein complexes measured by combination of protein engineering and solvent quenching meshodPrincipal Investigator
- Principal Investigator
  
  MAKABE koki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Yamagata University
  National Institutes of Natural Sciences Okazaki Research Facilities
ナノ世界のインターフェイス構築へのタンパク質工学的デザイン学
- Principal Investigator
  
  KUMAGAI IZUMI
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tohoku University
Structural fluctuations and functional expression of the chaperonin complexes
- Principal Investigator
  
  KUWAJIMA Kunihiro
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  National Institutes of Natural Sciences Okazaki Research Facilities
Study of the self-assembling nano-fibrils by protein design approachPrincipal Investigator
- Principal Investigator
  
  MAKABE Koki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biophysics
- Research Institution
  National Institutes of Natural Sciences Okazaki Research Facilities

[Journal Article] Addition of α-1,3-glucan-binding domains to α-1,3-glucanase Agn1p from　 <i>Schizosaccharomyces pombe</i> enhances hydrolytic activity of insoluble α-1,3-glucan2024
- Author(s)
  Horaguchi Yui、Yokomichi Moe、Takahashi Masaki、Xu Fusheng、Konno Hiroyuki、Makabe Koki、Yano Shigekazu
- Journal Title
  
  J. Gen. Appl. Microbiol.
  
  Volume: 70 Issue: 2 Pages: n/a
- DOI
  10.2323/jgam.2024.02.001
- ISSN
  0022-1260, 1349-8037
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05423
[Journal Article] α-1,3-Glucanase from the gram-negative bacterium Flavobacterium sp. EK-14 hydrolyzes fungal cell wall α-1,3-glucan2023
- Author(s)
  Takahashi Masaki、Yano Shigekazu、Horaguchi Yui、Otsuka Yuitsu、Suyotha Wasana、Makabe Koki、Konno Hiroyuki、Kokeguchi Susumu
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 21420-21420
- DOI
  10.1038/s41598-023-48627-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05423
[Journal Article] Cloning and structural basis of fluorescent protein color variants from identical species of sea anemone, Diadumene lineata2023
- Author(s)
  Horiuchi Yuki、Makabe Koki、Laskaratou Danai、Hatori Kuniyuki、Sliwa Michel、Mizuno Hideaki、Hotta Jun-ichi
- Journal Title
  
  Photochemical & Photobiological Sciences
  
  Volume: - Issue: 7 Pages: 1591-1601
- DOI
  10.1007/s43630-023-00399-0
- Data Source
  KAKENHI-PROJECT-23K23141
[Journal Article] Construction of IgG-Fab2 bispecific antibody via intein-mediated protein trans-splicing reaction2023
- Author(s)
  Risa Yamada, Ishin Nakahara, Izumi Kumagai, Ryutaro Asano, Takeshi Nakanishi, and Koki Makabe
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 15961-15961
- DOI
  10.1038/s41598-023-43110-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K04846, KAKENHI-PROJECT-23K24176
[Journal Article] Surface Engineering of Top7 to Facilitate Structure Determination2022
- Author(s)
  Yuki Ito, Takuya Araki, Shota Shiga, Hiroyuki Konno, Koki Makabe
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23(2) Issue: 2 Pages: 701-701
- DOI
  10.3390/ijms23020701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03511
[Journal Article] Mutational analysis of the effects of N-glycosylation sites on the activity and thermal stability of rutinosidase from Aspergillus oryzae2022
- Author(s)
  Koseki Takuya、Ishida Naoki、Hirota Ruka、Shiono Yoshihito、Makabe Koki
- Journal Title
  
  Enzyme and Microbial Technology
  
  Volume: 161 Pages: 110112-110112
- DOI
  10.1016/j.enzmictec.2022.110112
- Data Source
  KAKENHI-PROJECT-23K23141
[Journal Article] 二重特異性がん治療抗体の機能的な構造の理解に向けたあゆみ2021
- Author(s)
  浅野竜太郎, 真壁幸樹, 田中良和, 熊谷泉
- Journal Title
  
  医学のあゆみ
  
  Volume: 278 (6) Pages: 617-622
- Data Source
  KAKENHI-PROJECT-19H03511
[Journal Article] Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope2021
- Author(s)
  Makabe Koki、Yokoyama Takeshi、Uehara Shiro、Uchikubo-Kamo Tomomi、Shirouzu Mikako、Kimura Kouki、Tsumoto Kouhei、Asano Ryutaro、Tanaka Yoshikazu、Kumagai Izumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5790-5790
- DOI
  10.1038/s41598-021-84171-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0178, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19H02519, KAKENHI-PROJECT-19H03511, KAKENHI-PROJECT-20H02534, KAKENHI-PROJECT-19H02831, KAKENHI-PROJECT-19H00918
[Journal Article] Structural analysis of the β-sheet edge of peptide self-assembly using a model protein2021
- Author(s)
  Shota Shiga, Koki Makabe
- Journal Title
  
  Proteins
  
  Volume: 89(7) Issue: 7 Pages: 845-852
- DOI
  10.1002/prot.26063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03511
[Journal Article] Construction of a Circularly Connected VHH Bispecific Antibody (Cyclobody) for the Desirable Positioning of Antigen-Binding Sites.2020
- Author(s)
  Hemmi S, Asano R, Kimura K, Umetsu M, TNakanishi T, Kumagai I, Makabe K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 523(1) Issue: 1 Pages: 72-77
- DOI
  10.1016/j.bbrc.2019.12.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-17K08368, KAKENHI-PROJECT-19H03511, KAKENHI-PROJECT-20H00315
[Journal Article] Residue-Specific Binding Mechanisms of Thioflavin T to a Surface of Flat β-Sheets within a Peptide Self-Assembly Mimic2020
- Author(s)
  Sae Namioka, Norio Yoshida, Hiroyuki Konno, Koki Makabe
- Journal Title
  
  Biochemistry
  
  Volume: 59(30) Issue: 30 Pages: 2782-2787
- DOI
  10.1021/acs.biochem.0c00280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03511
[Journal Article] Cooperative unfolding of a single-layer β-sheet protein, CPAP G-box2020
- Author(s)
  Hideki Fujiwara, Shota Shiga, Koki Makabe
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 526(1) Issue: 1 Pages: 105-109
- DOI
  10.1016/j.bbrc.2020.03.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03511
[Journal Article] Structural considerations for functional anti-EGFR × anti-CD3 bispecific diabodies in light of domain order and binding affinity2018
- Author(s)
  1.Asano R., Nagai K., Makabe K., Takahashi K., Kumagai T., Kawaguchi H., Ogata H., Arai K., Umetsu M., Kumagai I.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 17 Pages: 13884-13893
- DOI
  10.18632/oncotarget.24490
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14227, KAKENHI-PROJECT-15H04306, KAKENHI-PROJECT-16K14483
[Journal Article] Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing2017
- Author(s)
  Yuki Shibuya, Natsuki Haga, Ryutaro Asano, Hikaru Nakazawa, Takamitsu Hattori, Daisuke Takeda Aruto Sugiyama, Reiko Kurotani, Izumi Kumagai, Mitsuo Umetsu, Koki Makabe
- Journal Title
  
  Protein Engineering, Design & Selection
  
  Volume: 30 Pages: 15-21
- DOI
  10.1093/protein/gzw057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J04866, KAKENHI-PROJECT-16K14483, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16K18296, KAKENHI-PROJECT-16H04570, KAKENHI-PROJECT-15K09208
[Journal Article] Zinc ion-binding activity of an anti-ZnO VHH antibody, 4F22015
- Author(s)
  Ryosuke Sasaki, Soichiro Kitazawa, Ryo Kitahara, Hikaru Nakazawa, Yoshikazu Tanaka, Izumi Kumagai, Mitsuo Umetsu, and Koki Makabe
- Journal Title
  
  Chem. Lett.
  
  Volume: 44 Issue: 10 Pages: 1309-1311
- DOI
  10.1246/cl.150537
- NAID
  130005101454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670051, KAKENHI-PROJECT-25840025, KAKENHI-PROJECT-24000011
[Journal Article] Aromatic cluster mutations produce focal modulations of β-sheet structure.2015
- Author(s)
  Biancalana M, Makabe K, Yan S, Koide S.
- Journal Title
  
  Protein Sci.
  
  Volume: epub Issue: 5 Pages: 841-849
- DOI
  10.1002/pro.2657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670051
[Journal Article] Dissection of the ATP-dependent conformational change cycle of a group II chaperonin.2014
- Author(s)
  Nakagawa A, Moriya K, Arita M, Yamamoto Y, Kitamura K, Ishiguro N, Kanzaki T, Oka T, Makabe K, Kuwajima K, Yohda M.
- Journal Title
  
  J Mol Biol.
  
  Volume: 426 Issue: 2 Pages: 447-459
- DOI
  10.1016/j.jmb.2013.09.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24370064, KAKENHI-PROJECT-25440075
[Journal Article] Native-state Heterogeneity ofβ2-Microglobulin as Revealed by Kinetic Folding and Real-time NMR Experiments2013
- Author(s)
  Mukaiyama A, Nakamura T, Makabe K, Maki K, Goto Y, Kuwajima K
- Journal Title
  
  J Mol Biol
  
  Volume: 425 Pages: 257-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] NMR characterization of the interaction of GroEL with amyloid β as a model ligand.2013
- Author(s)
  Yagi-Utsumi, M., Kunihara, T., Nakamura, T., Uekusa, Y., Makabe, K., Kuwajima, K. & Kato, K.
- Journal Title
  
  FEBS Lett.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] The Molten Globule ofβ2-Microglobulin Accumulated at pH 4 and Its Role in Protein Folding2013
- Author(s)
  Mukaiyama A, Nakamura T, Makabe K, Maki K, Goto Y, Kuwajima K
- Journal Title
  
  J Mol Biol
  
  Volume: 425 Pages: 273-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] The H/D-exchange Kinetics of the Escherichia coli Co-chaperonin GroES Studied by 2D-NMR and DMSO-Quenched Exchange Methods2013
- Author(s)
  Chandak MS, Nakamura T, Makabe K, Takenaka T, Mukaiyama A, Chaudhuri TK, Kato K, Kuwajima K
- Journal Title
  
  J Mol Biol
  
  Volume: 425 Pages: 2541-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] The H/D-Exchange Kinetics of the Escherichia coli Co-Chaperonin GroES Studied by 2D NMR and DMSO-Quenched Exchange Methods.2013
- Author(s)
  Chandak, M.S., Nakamura, T., Makabe, K., Takenaka, T., Mukaiyama, A., Chaudhuri, T.K., Kato, K. & Kuwajima, K.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Structural insights into the stability perturbations induced by N-terminal variation in human and goat α-lactalbumin.2013
- Author(s)
  Makabe, K., Nakamura, T. & Kuwajima, K.
- Journal Title
  
  Protein Eng. Des. Sel.
  
  Volume: 26 Pages: 165-170
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] The molten globule of β(2)-microglobulin accumulated at pH 4 and its role in protein folding2013
- Author(s)
  A. Mukaiyama, T. Nakamura, K. Makabe, K. Maki, Y. Goto, K. Kuwajima
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 425 Issue: 2 Pages: 273-291
- DOI
  10.1016/j.jmb.2012.11.002
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20107001, KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PLANNED-20107009
[Journal Article] ATP dependent rotational motion of group II chaperonin observed by X-ray single molecule tracking2013
- Author(s)
  Sekiguchi H, Nakagawa A, Moriya K, Makabe K, Ichiyanagi K, Nozawa S, Sato T, Adachi S, Kuwajima K, Yohda M, Sasaki YC
- Journal Title
  
  PLoS One
  
  Volume: 29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] NMR characterization of interaction of GroEL with amyloid β as a model ligand.2013
- Author(s)
  M.Yagi-Utsumi, T.Kunihara, T.Nakamura, Y.Uekusa, K.Makabe, K.Kuwajima, and K.Kato
- Journal Title
  
  FEBS Lett.
  
  Volume: 587 Issue: 11 Pages: 605-609
- DOI
  10.1016/j.febslet.2013.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107004, KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-23870043, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25440075, KAKENHI-PLANNED-20107009
[Journal Article] The molten globule of β_2-microglobulin accumulated at pH 4 and its role in protein folding.2013
- Author(s)
  Mukaiyama, A., Nakamura, T., Makabe, K., Maki, K., Goto, Y. & Kuwajima, K.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 425 Pages: 273-291
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes.2013
- Author(s)
  Nakamura, T., Aizawa, T., Kariya, R., Okada, S., Demura, M., Kawano, K., Makabe, K. & Kuwajima, K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 14408-14416
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Native-state heterogeneity of β_2-microglobulin as revealed by kinetic folding and real-time NMR experiments.2013
- Author(s)
  Mukaiyama, A., Nakamura, T., Makabe, K., Maki, K., Goto, Y. & Kuwajima, K.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 425 Pages: 257-272
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Molecular mechanisms of the cytotoxicity of humanα-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes2013
- Author(s)
  Nakamura T, Aizawa T, Kariya R, Okada S, Demura M, Kawano K, Makabe K, Kuwajima K
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 14408-14416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] Structural insights into the stability perturbations induced by N-terminal variation in human and goat α-lactalbumin.2013
- Author(s)
  Makabe K, Nakamura T, Kuwajima K
- Journal Title
  
  Protein Eng Des Sel.
  
  Volume: 26 Issue: 2 Pages: 165-170
- DOI
  10.1093/protein/gzs093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011
[Journal Article] Structural insights into the stability perturbations induced by N-terminal variation in human and goatα-lactalbumin2013
- Author(s)
  Makabe K, Nakamura T, Kuwajima K
- Journal Title
  
  Protein Eng Des Sel
  
  Volume: 26 Pages: 165-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and non-substrate tRNA via an induced-fit process2013
- Author(s)
  Ochi A, Makabe K, Yamagami R, Hirata A, Sakaguchi R, Hou YM, Watanabe K, Nureki O, Kuwajima K, Hori H
- Journal Title
  
  J Biol Chem
  
  Volume: 30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and nonsubstrate tRNA via an induced-fit process.2013
- Author(s)
  A. Ochi, K. Makabe, R. Yamagami, A. Hirata, R. Sakaguchi, Y.M. Hou, K. Watanabe, O. Nureki, K. Kuwajima, and H. Hori
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 35 Pages: 25562-25574
- DOI
  10.1074/jbc.m113.485128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081, KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25440075
[Journal Article] NMR characterization of the interaction of GroEL with amyloidβas a model ligand2013
- Author(s)
  Yagi-Utsumi M, Kunihara T, Nakamura T, Uekusa Y, Makabe K, Kuwajima K, Kato K
- Journal Title
  
  FEBS Lett
  
  Volume: 587 Pages: 1605-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] The H/D-exchange Kinetics of the Escherichia coli Co-chaperonin GroES Studied by 2D-NMR and DMSO-Quenched Exchange Methods.2013
- Author(s)
  Chandak MS, Nakamura T, Makabe K, Takenaka T, Mukaiyama A, Chaudhuri TK, Kato K, Kuwajima K.
- Journal Title
  
  J Mol Biol.
  
  Volume: 425 Issue: 14 Pages: 2541-2560
- DOI
  10.1016/j.jmb.2013.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25440075, KAKENHI-PLANNED-20107009
[Journal Article] ATP dependent rotational motion of group II chaperonin observed by X-ray single molecule tracking.2013
- Author(s)
  Sekiguchi H, Nakagawa A, Moriya K, Makabe K, Ichiyanagi K, Nozawa S, Sato T, Adachi S, Kuwajima K, Yohda M, Sasaki YC.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 5 Pages: e64176-e64176
- DOI
  10.1371/journal.pone.0064176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24370064, KAKENHI-PROJECT-25440075
[Journal Article] Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes.2013
- Author(s)
  Nakamura T, Aizawa T, Kariya R, Okada S, Demura M, Kawano K, Makabe K, Kuwajima K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288 Issue: 20 Pages: 14408-14416
- DOI
  10.1074/jbc.m112.437889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25440075
[Journal Article] Native-state heterogeneity of β(2)-microglobulin as revealed by kinetic folding and real-time NMR experiments.2013
- Author(s)
  Mukaiyama A, Nakamura T, Makabe K, Maki K, Goto Y, Kuwajima K.
- Journal Title
  
  J Mol Biol.
  
  Volume: 425 Issue: 2 Pages: 257-272
- DOI
  10.1016/j.jmb.2012.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194, KAKENHI-PLANNED-20107009
[Journal Article] Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone2012
- Author(s)
  Chen J, Yagi H, Sormanni P, Vendruscolo M, Makabe K, Nakamura T, Goto Y, Kuwajima K.
- Journal Title
  
  FEBS Letters
  
  Volume: 586 Pages: 1120-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] Fibrillogenic propensity of the GroEL apical domain : A Janus-faced minichaperone2012
- Author(s)
  Chen J, Yagi H, Sormanni P, Vendruscolo M, Makabe K, Nakamura T, Goto Y, Kuwajima K
- Journal Title
  
  FEBS Letters
  
  Volume: 586 Pages: 1120-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] Fibrillogenic propensity of the GroEL apical domain: a Janus-faced minichaperone.2012
- Author(s)
  Chen, J., Yagi, H., Sormanni, P., Vendruscolo, M., Makabe, K., Nakamura, T., Goto, Y. & Kuwajima, K.
- Journal Title
  
  FEBS Lett.
  
  Volume: 586 Pages: 1120-1127
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Sequential four-state folding/unfolding of goat α-lactalbumin and its N-terminal variants.2012
- Author(s)
  Tomoyori K, Nakamura T, Makabe K, Maki K, Saeki K, Kuwajima K.
- Journal Title
  
  Proteins.
  
  Volume: 80 Issue: 9 Pages: 2191-2206
- DOI
  10.1002/prot.24109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] Sequential four-state folding/unfolding of goat α-lactalbumin and its N-terminal variants.2012
- Author(s)
  Tomoyori, K., Nakamura, T., Makabe, K., Maki, K., Saeki, K. & Kuwajima, K.
- Journal Title
  
  Proteins
  
  Volume: 80 Pages: 2191-2206
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Sequential Four-state Folding/unfolding of Goatα-Lactalbumin and Its N-Terminal Variants Proteins2012
- Author(s)
  Tomoyori K, Nakamura T, Makabe K, Maki K, Saeki K, Kuwajima K
- Volume
  80
- Pages
  2191-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] Dissecting a Bimolecular Process of MgATP2- Binding to the Chaperonin GroEL2011
- Author(s)
  Chen J, Makabe K, Nakamura T, Inobe T, Kuwajima K
- Journal Title
  
  J Mol Biol
  
  Volume: 410 Pages: 343-356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] Dissecting a bimolecular process of MgATP2- binding to the chaperonin GroEL.2011
- Author(s)
  Chen J, Makabe K, Nakamura T, Inobe T, Kuwajima K.
- Journal Title
  
  J Mol Biol
  
  Volume: 412 Pages: 343-356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770194
[Journal Article] Dissecting a bimolecular process of MgATP^2- binding to the chaperonin GroEL.2011
- Author(s)
  Chen, J., Makabe, K., Nakamura, T., Inobe, T., Kuwajima, K.
- Journal Title
  
  J.Mol.Biol. in the press.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Dissecting a bimolecular process of MgATP^<2-> binding to the chaperonin GroEL.2011
- Author(s)
  Chen, J., Makabe, K., Nakamura, T., Inobe, T. & Kuwajima, K.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 410 Pages: 343-356
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Different folding pathways taken by highly homologous proteins, goat α-lactalbumin and canine milk lysozyme.2010
- Author(s)
  Nakamura, T., Makabe, K., Tomoyori, K., Maki, K., Mukaiyama, A. & Kuwajima, K.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 396 Pages: 1361-1378
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Different Folding Pathways Taken by Highly Homologous Proteins, Goat alpha-Lactalbumin and Canine Milk Lysozyme.2010
- Author(s)
  Nakamura T, Makabe K, Tomoyori K, Maki K, Mukaiyama A, Kuwajima K.
- Journal Title
  
  J Mol Biol. 396
  
  Pages: 1361-1378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] Different folding pathways taken by highly homologous proteins, goat α-lactalbumin and canine milk lysozyme.2010
- Author(s)
  Nakamura, T., Makabe, K., Tomoyori, K., Maki, K., Mukaiyama, A., Kuwajima, K.
- Journal Title
  
  J.Mol.Biol. 396
  
  Pages: 1361-1378
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Different folding pathways taken by highly homologous proteins, goat alpha-lactalbumin and canine milk lysozyme2010
- Author(s)
  Nakamura T, Makabe K, Tomoyori K, Maki K, Mukaiyama A, Kuwajima K.
- Journal Title
  
  J Mol Biol. 396
  
  Pages: 1361-1378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] Minimalist design of water-soluble cross-beta architecture.2010
- Author(s)
  Biancalana M, Makabe K, Koide S.
- Journal Title
  
  Proc Natl Acad Sci U S A. 107
  
  Pages: 3469-3474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] βシートの構造構築機構2010
- Author(s)
  真壁幸樹
- Journal Title
  
  生物物理
  
  Volume: 50 Pages: 126-127
- NAID
  10026476932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22226013
[Journal Article] Flexible recognition of the tRNA G18 methylation target site by TrmH methyltransferase through first binding and induced fit processes.2010
- Author(s)
  Ochi, A., Makabe, K., Kuwajima, K. & Hori, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 285 Pages: 9018-9029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107009
[Journal Article] Flexible recognition of the tRNA G18 methylation target site by TrmH methyltransferase through first binding and induced fit processes.2010
- Author(s)
  Ochi A, Makabe K, Kuwajima K, Hori H.
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 9018-9029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] Minimalist design of water-soluble cross-beta architecture2010
- Author(s)
  Biancalana M, Makabe K, Koide S.
- Journal Title
  
  Proc Natl Acad Sci USA 107
  
  Pages: 3469-3474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies2009
- Author(s)
  Biancalana M, Makabe K, Koide A, Koide S.
- Journal Title
  
  J Mol Biol. 385
  
  Pages: 1052-1063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] Molecular Mechanism of Thioflavin-T Binding to the Surface of beta-Rich Peptide Self-Assemblies.2009
- Author(s)
  Biancalana M, Makabe K, Koide A, Koide S.
- Journal Title
  
  J Mol Biol. 385
  
  Pages: 1052-1063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] Structural Basis for Exquisite Specificity of Affinity Clamps, Synthetic Binding Proteins Generated through Directed Domain-interface Evolution.2009
- Author(s)
  Huang J, Makabe K, Biancalana M, Koide A, Koide S.
- Journal Title
  
  J Mol Biol. 392
  
  Pages: 1221-1231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution2009
- Author(s)
  Huang J, Makabe K, Biancalana M, Koide A, Koide S.
- Journal Title
  
  J Mol Biol. 392
  
  Pages: 1221-1231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] The promiscuity of beta-strand pairing allows for rational design of beta-sheet face inversion2008
- Author(s)
  Makabe K, Koide S.
- Journal Title
  
  J Am Chem Soc. 130
  
  Pages: 14370-14371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Journal Article] The promiscuity of beta-strand pairing allows for rational design of beta-sheet face inversion.2008
- Author(s)
  Makabe K, Koide S.
- Journal Title
  
  J Am Chem Soc. 130
  
  Pages: 14370-14371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870043
[Patent] 蛋白質-化学療法剤複合体及びその製造方法,並びに医薬2012
- Inventor(s)
  桑島邦博、中村敬、真壁幸樹、岡田誠治
- Industrial Property Rights Holder
  自然科学研究機構、熊本大学
- Industrial Property Number
  2012-147492
- Filing Date
  2012-06-29
- Data Source
  KAKENHI-PLANNED-20107009
[Patent] 蛋白質―化学療法剤複合体及びその製造方法,並びに医薬への応用2012
- Inventor(s)
  桑島邦博,中村敬,真壁幸樹,岡田誠治
- Industrial Property Rights Holder
  分子科学研究所、熊本大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-147492
- Filing Date
  2012
- Data Source
  KAKENHI-PROJECT-23770194
[Patent] 球状蛋白質の準安定状態を用いた抗癌細胞作用のある分子の作成2011
- Inventor(s)
  桑島邦博、中村敬、真壁幸樹
- Industrial Property Rights Holder
  自然科学研究機構
- Industrial Property Number
  2011-238611
- Filing Date
  2011-10-31
- Data Source
  KAKENHI-PLANNED-20107009
[Patent] 球状蛋白質の準安定状態を用いた抗癌細胞作用のある分子の作成2011
- Inventor(s)
  桑島邦博, 中村敬, 真壁幸樹
- Industrial Property Rights Holder
  自然科学研究機構
- Industrial Property Number
  2011-238611
- Filing Date
  2011-10-31
- Data Source
  KAKENHI-PLANNED-20107009
[Patent] 球状蛋白質の準安定状態を用いた抗癌細胞作用のある分子の作成2011
- Inventor(s)
  桑島邦博,中村敬,真壁幸樹
- Industrial Property Rights Holder
  分子科学研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-238611
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23770194
[Patent] 蛋白質-脂肪酸複合体及び腫瘍細胞の細胞死誘導薬2011
- Inventor(s)
  桑島邦博、中村敬、真壁幸樹
- Industrial Property Rights Holder
  自然科学研究機構
- Industrial Property Number
  2011-238611
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23770194
[Presentation] Lysobacter sp. MK9-1由来キチナーゼChi19MKの構造解析2024
- Author(s)
  横道萌、菅野春樹、真壁幸樹、今野博行、矢野成和
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-22K05423
[Presentation] Lysobacter sp. MK9-1由来GH19型キチナーゼChi19MKのドメイン構造と機能解析2023
- Author(s)
  横道萌、佐藤宏紀、真壁幸樹、矢野成和
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PROJECT-22K05423
[Presentation] 蛋白質連結反応による二重特異性抗体の作製技術2023
- Author(s)
  真壁幸樹
- Organizer
  日本化学会第103春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24176
[Presentation] Schizosaccharomyces pombe由来α-1,3-グルカナーゼの解析2023
- Author(s)
  洞口友依, 矢野成和, 真壁幸樹, 今野博行
- Organizer
  日本農芸化学会東北支部　第158回大会
- Data Source
  KAKENHI-PROJECT-22K05423
[Presentation] 蛋白質連結技術によるIgG型二重特異性抗体の作製におけるFcエンジニアリング2023
- Author(s)
  真壁幸樹
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24176
[Presentation] 蛋白質ライゲーション反応と特異的ペアリングによる二重特異性抗体の構築2023
- Author(s)
  真壁幸樹
- Organizer
  蛋白研セミナー　蛋白質に挑戦する化学
- Invited
- Data Source
  KAKENHI-PROJECT-23K24176
[Presentation] Molecular basis of the hyper-activity of anti-cancer bispecific antibody due to domain rearrangement revealed by cryo-EM2023
- Author(s)
  Kyohei Sato, Ryutaro Asano, Koki Makabe, Izumi Kumagai, Takashi Matsui, Shiro Uehara, Atsushi Tsugita, Takeshi Yokoyama, Yoshikazu Tanaka
- Organizer
  第61回日本生物物理学年会
- Data Source
  KAKENHI-PROJECT-23K24176
[Presentation] Flavobacterium sp. EK-14由来α-1,3-グルカナーゼのC-末端領域の役割2023
- Author(s)
  髙橋将毅、矢野成和、真壁幸樹、今野博行、苔口進
- Organizer
  日本農芸化学会東北支部　第158回大会
- Data Source
  KAKENHI-PROJECT-22K05423
[Presentation] 蛋白質連結による二重特異性抗体の構築2023
- Author(s)
  真壁幸樹
- Organizer
  CHEMINAS48
- Invited
- Data Source
  KAKENHI-PROJECT-23K24176
[Presentation] 蛋白質連結と特異的ペアリングによる多様な二重特異性抗体の構築技術2023
- Author(s)
  真壁幸樹
- Organizer
  第二回日本抗体学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24176
[Presentation] がん治療薬を指向した環状型小型バイスペシフィック抗体(Cyclobody BiTE)の構築と評価2022
- Author(s)
  山田梨沙、中原維新、中西猛、浅野竜太郎、真壁幸樹
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H03511
[Presentation] Construction and evaluation of an amyloid catalyst mimicking artificial protein2022
- Author(s)
  Akifumi Takase and Koki Makabe
- Organizer
  第59回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-23K23141
[Presentation] 環状型小型バイスペシフィック抗体(Cyclobody BiTE)の構築と評価2022
- Author(s)
  山田梨沙、中原維新、中西猛、浅野竜太郎、真壁幸樹
- Organizer
  2021年度生物物理学会北海道支部・東北支部合同例会
- Data Source
  KAKENHI-PROJECT-19H03511
[Presentation] Protein engineering for biogeeks; practical examples of structural redesigns of a model protein and therapeutic antibody designs2022
- Author(s)
  真壁幸樹
- Organizer
  生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24176
[Presentation] Characterization of circularly connected VHH bispecific antibody, Cyclobody2019
- Author(s)
  逸見早紀、浅野竜太郎、木村昂稀、梅津光央、中西猛、熊谷泉、真壁幸樹
- Organizer
  2019年化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H03511
[Presentation] 環状VHH二重特異性抗体Cyclobodyの機能評価2019
- Author(s)
  逸見早紀、木村昂稀、梅津光央、中西猛、浅野竜太郎、真壁幸樹
- Organizer
  蛋白質科学会第19回年会
- Data Source
  KAKENHI-PROJECT-19H03511
[Presentation] 蛋白質トランススプライシングを用いた小型二重特異性抗体の構築2017
- Author(s)
  芳賀奈月、澁谷優希、浅野竜太郎、梅津光央、真壁幸樹
- Organizer
  日本化学会第97春期年会
- Place of Presentation
  慶応大学日吉キャンパス(横浜市)
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 蛋白質トランススプライシングを用いた小型二重特異性抗体の構築と抗体の蛍光ベル化2016
- Author(s)
  芳賀奈月、澁谷優希、浅野竜太郎、梅津光央、真壁幸樹
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2016-06-08
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 抗酸化亜鉛VHH抗体の亜鉛イオン結合特性2015
- Author(s)
  真壁幸樹
- Organizer
  生物物理学会年会 2015
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26670051
[Presentation] βシートモデルタンパク質へのアミロイドコア配列の移植とその構造評価2015
- Author(s)
  堀裕基、真壁幸樹
- Organizer
  蛋白質科学会年会 2015
- Place of Presentation
  徳島阿波銀ホール
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-26670051
[Presentation] Construction of a bispecific antibody via protein trans-splicing2015
- Author(s)
  真壁幸樹
- Organizer
  Pacifichem 2015
- Place of Presentation
  Sheraton Waikiki　（アメリカ合衆国）
- Year and Date
  2015-12-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670051
[Presentation] Folding and redesign of a beta-sheet rich model protein2013
- Author(s)
  Koki Makabe
- Organizer
  International symposium on protein folding and its biological significance
- Place of Presentation
  Okazaki, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-23770194
[Presentation] Folding and redesign of a beta-sheet rich model protein2013
- Author(s)
  Koki Makabe
- Organizer
  International symposium on protein folding and its biological significance
- Place of Presentation
  岡崎
- Year and Date
  2013-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-23770194
[Presentation] Structural fluctuation of free GroES and the GroES-SR1 complex studied by the use of hydrogen/deuterium (H/D) exchange.2013
- Author(s)
  Chandak, M.S., Nakamura, T., Makabe, K., Takenaka, T., Mukaiyama, A., Chaudhuri, T.K., Chen, J., Kato, K. & Kuwajima, K.
- Organizer
  57th Annual Meeting of the Biophysical Society (USA)
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PLANNED-20107009
[Presentation] STRUCTURAL INSIGHTS INTO THE STABILITY PERTURBATIONS BY N-TERMINAL VARIATIONS IN HUMAN AND GOAT ALPHA-LACTALBUMIN2012
- Author(s)
  Koki Makabe, Takashi Nakamura and Kunihiro Kuwajima
- Organizer
  Korea-Japan Seminars on Biomolecular Sciences Experiments and Simulations
- Place of Presentation
  奈良
- Year and Date
  2012-01-09
- Invited
- Data Source
  KAKENHI-PROJECT-23770194
[Presentation] STRUCTURAL INSIGHTS INTO THE STABILITY PERTURBATIONS BY N-TERMINAL VARIATIONS IN HUMAN AND GOAT ALPHA-LACTALBUMIN2012
- Author(s)
  Koki Makabe, Takashi Nakamura and Kunihiro Kuwajima
- Organizer
  Korea-Japan Seminars on Biomolecular Sciences　Experiments and Simulations(招待講演)
- Place of Presentation
  東大寺文化センター（奈良県）
- Data Source
  KAKENHI-PROJECT-23770194
[Presentation] モデル蛋白質によるβシート構造の再設計2012
- Author(s)
  真壁幸樹
- Organizer
  平成24年生物物理学会東北支部会
- Place of Presentation
  仙台
- Year and Date
  2012-12-21
- Data Source
  KAKENHI-PROJECT-23770194
[Presentation] βシート蛋白質の構造形成機構2010
- Author(s)
  真壁幸樹, 小出昌平, 桑島邦博
- Organizer
  生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-20870043
[Presentation] Protein design approach for beta-sheet characterization2009
- Author(s)
  Koki Makabe
- Organizer
  北海道大学-Mahidol 大学若手合同シンポジウム
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2009-05-12
- Data Source
  KAKENHI-PROJECT-20870043
[Presentation] Structures of β-Sheet Self-Assembly Mimics2009
- Author(s)
  Koki Makabe, Shohei Koide, Kunihiro Kuwajima
- Organizer
  Asia Core
- Place of Presentation
  韓国, ソウル
- Data Source
  KAKENHI-PROJECT-20870043
[Presentation] -シート形成における主鎖水素結合の役割2009
- Author(s)
  真壁幸樹, 小出昌平, 桑島邦博
- Organizer
  蛋白質科学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20870043
[Presentation] Protein design approach for β-sheet characterization2009
- Author(s)
  Koki Makabe
- Organizer
  北海道大学-Mahidol大学若手合同シンポジウム
- Data Source
  KAKENHI-PROJECT-20870043
[Presentation] Structures of β-Sheet Self-Assembly Mimics2009
- Author(s)
  Makabe K
- Organizer
  First Korea-Japan Seminars on Biomolecular Sciences-Experiments and Simulations
- Place of Presentation
  KIAS, Seoul, Korea
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-20870043

1. ASANO RYUTARO (80323103)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. KUMAGAI IZUMI (10161689)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. TANAKA YOSHIKAZU (20374225)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
4. UMETSU MITSUO (70333846)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 矢野成和 (50411228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. KUWAJIMA Kunihiro (70091444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
7. TSUMOTO KOUHEI (90271866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 古本祥三 (00375198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 片桐洋史 (40447206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 吉田紀生 (10390650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 加藤晃一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 堀弘幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 平田章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中西猛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Makabe Koki 眞壁 幸樹

MAKABE Koki 真壁 幸樹

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アミロイド触媒型の原始酵素モデルに着想した人工酵素のデザインと応用Principal Investigator

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Construction of bispecific antibodies from the camelid antibody VHHs via in-cell protein trans-splicingPrincipal Investigator

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Structural fluctuations of protein complexes measured by combination of protein engineering and solvent quenching meshodPrincipal Investigator

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Study of the self-assembling nano-fibrils by protein design approachPrincipal Investigator

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[Journal Article] Addition of α-1,3-glucan-binding domains to α-1,3-glucanase Agn1p from <i>Schizosaccharomyces pombe</i> enhances hydrolytic activity of insoluble α-1,3-glucan2024

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[Journal Article] α-1,3-Glucanase from the gram-negative bacterium Flavobacterium sp. EK-14 hydrolyzes fungal cell wall α-1,3-glucan2023

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Makabe Koki 眞壁幸樹

MAKABE Koki 真壁幸樹

[Journal Article] Addition of α-1,3-glucan-binding domains to α-1,3-glucanase Agn1p from　 <i>Schizosaccharomyces pombe</i> enhances hydrolytic activity of insoluble α-1,3-glucan2024