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SASAKI TSUTOMU  佐々木 勉

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SASAKI Tsutomu  佐々木 勉

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Researcher Number 20534879
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院 医学系研究科, 特任教授(常勤)
Affiliation (based on the past Project Information) *help 2023 – 2024: 大阪大学, 大学院医学系研究科, 特任教授(常勤)
2022 – 2023: 大阪大学, 大学院医学系研究科, 寄附講座准教授
2022: 大阪大学, 大学院医学系研究科, 特任教授
2020 – 2021: 大阪大学, 医学系研究科, 寄附講座准教授
2017 – 2019: 大阪大学, 医学系研究科, 講師
2010 – 2016: 大阪大学, 医学部附属病院, 助教
2009: Osaka University, 医学系研究科, 助教
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 52020:Neurology-related / Applied pharmacology
Except Principal Investigator
Basic Section 38050:Food sciences-related / Medium-sized Section 38:Agricultural chemistry and related fields / Epidemiology and preventive medicine / Food science / Neurology
Keywords
Principal Investigator
脳虚血 / 血液脳関門 / 血管内皮細胞 / 低分子化合物 / パーキンソン病 / CREB / occludin / claudin / 脳梗塞 / アストロサイト … More / 神経病態 / クロ―ディン / オクルディン / クローディン / グリア細胞 / タイトジャンクション / トランスレーショナルリサーチ / 創薬化学 / 蛋白蛋白相互作用 / 蛋白質 / 脳神経疾患 / 神経保護剤 / 蛋白相互作用阻害剤 / 血管内皮 / 神経細胞 / MDMX / MDM2 / p53 / PPI阻害剤 / 脳卒中 / 神経疾患 / TORC / エピゲノム / アポトーシス / HDAC / SIK(塩誘導性キナーゼ) / CRTC / 創薬 / HDAC阻害剤 / HDAC(ヒストン脱アセチル化酵素) / SIK(塩誘導性キナーゼ) / CREB / シグナルトランスダクション / 虚血耐性 / NDMA受容 / TORC1 / α7 nchR / サブタイプ / NDMA受容体 / SIK2 / TORC1/ CRTC1 / NR2B / NR2A / NMDA受容体 … More
Except Principal Investigator
転写因子 / 油脂 / 肥満 / 高脂肪食 / 嗜好性 / 糖尿病 / cAMP / 神経 / 過食 / 油脂摂取 / 神経細胞 / 脂肪 / 嗜好 / 臨床疫学 / 社会医学 / 認知機能低下 / 脳血管障害 / 血栓溶解療法 / 急性期脳梗塞 / バイオバンク / 認知機能 / 急性期脳卒中 / 認知機能検査 / 認知機能障害 / ラクナ梗塞 / 脳卒中 / 脳小血管病 / disability / cotnitive impairment / cerebrovascular disease / 行動学 / 生理学 / 栄養学 / 褐色脂肪組織 / ストレス / 脳血流 / db/db マウス / 慢性低潅流 / db/dbマウス / インスリン抵抗性 / 脳虚血 / 高血圧 / 造血因子 / 慢性脳低灌流 / 側副血行 Less
  • Research Projects

    (10 results)
  • Research Products

    (103 results)
  • Co-Researchers

    (29 People)
  •  Neuronal mechanism of hyperphagia in High fat foods

    • Principal Investigator
      松村 成暢
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Osaka Metropolitan University
  •  Significance of tight junctions in glial cells and their involvement in neuropathologyPrincipal Investigator

    • Principal Investigator
      Sasaki Tsutomu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Osaka University
  •  Mechanism of suppression and induction of obesity by dietary fat

    • Principal Investigator
      Matsumura Shigenobu
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Osaka Metropolitan University
      Osaka Prefecture University
      Kyoto University
  •  Mechanism of obesity in female CRTC1 Knockout mice

    • Principal Investigator
      Matsumura Shigenobu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      Kyoto University
  •  Research for cerebrovascular disease-related conditions

    • Principal Investigator
      Kaori Miwa
    • Project Period (FY)
      2017 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Epidemiology and preventive medicine
    • Research Institution
      National Cardiovascular Center Research Institute
      Osaka University
  •  Obesity induced by fat palatability and mental stress

    • Principal Investigator
      Matsumura Shigenobu
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      Kyoto University
  •  Novel therapy for neurological disorders by protein-protein interaction inhibitorPrincipal Investigator

    • Principal Investigator
      SASAKI Tsutomu
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied pharmacology
    • Research Institution
      Osaka University
  •  The role and mechanisms of TORC and HDAC signaling pathway and therapeutic new-class small compounds for neurological diseasePrincipal Investigator

    • Principal Investigator
      sasaki tsutomu
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Osaka University
  •  Mechanisms of arteriogenesis enhancement by granulocyte colony stimulating factor – Potential application to patients with subacute ischemic stroke

    • Principal Investigator
      KITAGAWA KAZUO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Osaka University
  •  Differential contribution of individual receptor subunits of N-methyl-d-aspartate to ischemic neuronal damage.Principal Investigator

    • Principal Investigator
      SASAKI Tsutomu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent Other

  • [Book] 最新臨床脳卒中学(第2版)下 最新の診断と治療 ラクナ梗塞の急性期治療2022

    • Author(s)
      藤堂 謙一、佐々木 勉、望月 秀樹
    • Total Pages
      703
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Book] 最新臨床脳卒中学(第2版)上 最新の診断と治療   治療概論 慢性期の内科治療2022

    • Author(s)
      佐々木 勉、権 泰史、藤堂 謙一
    • Total Pages
      703
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Journal Article] The tight junction protein occludin modulates blood brain barrier integrity and neurological function after ischemic stroke in mice2023

    • Author(s)
      Sugiyama Shintaro、Sasaki Tsutomu、Tanaka Hiroo、Yan Haomin、Ikegami Takeshi、Kanki Hideaki、Nishiyama Kumiko、Beck Goichi、Gon Yasufumi、Okazaki Shuhei、Todo Kenichi、Tamura Atsushi、Tsukita Sachiko、Mochizuki Hideki
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 2892-2892

    • DOI

      10.1038/s41598-023-29894-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07414, KAKENHI-PROJECT-20K16497, KAKENHI-PROJECT-20K06910, KAKENHI-PROJECT-19H03453, KAKENHI-PROJECT-21K15092, KAKENHI-PROJECT-19H05468
  • [Journal Article] <scp>CRTC1</scp> deficiency, specifically in melanocortin‐4 receptor‐expressing cells, induces hyperphagia, obesity, and insulin resistance2022

    • Author(s)
      Matsumura Shigenobu、Miyakita Motoki、Miyamori Haruka、Kyo Satomi、Ishikawa Fuka、Sasaki Tsutomu、Jinno Tomoki、Tanaka Jin、Fujita Kotomi、Yokokawa Takumi、Goto Tsuyoshi、Momma Keiko、Takenaka Shigeo、Inoue Kazuo
    • Journal Title

      The FASEB Journal

      Volume: 36 Issue: 12

    • DOI

      10.1096/fj.202200617r

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02909, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330
  • [Journal Article] MDMX elevation by a novel Mdmx?p53 interaction inhibitor mitigates neuronal damage after ischemic stroke2022

    • Author(s)
      Yan Haomin、Sasaki Tsutomu、Kanki Hideaki、Hirata Yoshiyuki、Nishiyama Kumiko、Hisada Sunao、Matsumura Shigenobu、Nagaoka Yasuo、Sumiyoshi Takaaki、Nagano Seiichi、Nakata Akiko、Yoshida Minoru、Uesato Shinichi、Mochizuki Hideki
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 21110-21110

    • DOI

      10.1038/s41598-022-25427-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07414, KAKENHI-PROJECT-21H02841, KAKENHI-PROJECT-19H05640
  • [Journal Article] Stimulation of G<sub>s</sub> signaling in MC4R cells by DREADD increases energy expenditure, suppresses food intake, and increases locomotor activity in mice2022

    • Author(s)
      Matsumura Shigenobu、Miyakita Motoki、Miyamori Haruka、Kyo Satomi、Shima Daisuke、Yokokawa Takumi、Ishikawa Fuka、Sasaki Tsutomu、Jinno Tomoki、Tanaka Jin、Goto Tsuyoshi、Momma Keiko、Ishihara Kengo、Berdeaux Rebecca、Inoue Kazuo
    • Journal Title

      American Journal of Physiology-Endocrinology and Metabolism

      Volume: 322 Issue: 5 Pages: E436-E445

    • DOI

      10.1152/ajpendo.00439.2021

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330, KAKENHI-PROJECT-19H02909
  • [Journal Article] Disruption of CRTC1 and CRTC2 in Sim1 cells strongly increases high-fat diet intake in female mice but has a modest impact on male mice2022

    • Author(s)
      Tanaka Jin、Ishikawa Fuka、Jinno Tomoki、Miyakita Motoki、Miyamori Haruka、Sasaki Tsutomu、Yokokawa Takumi、Goto Tsuyoshi、Inoue Kazuo、Matsumura Shigenobu
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 1 Pages: e0262577-e0262577

    • DOI

      10.1371/journal.pone.0262577

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H02909, KAKENHI-PROJECT-20K19498, KAKENHI-PROJECT-19K24330
  • [Journal Article] MiRNA-132/212 regulates tight junction stabilization in blood brain barrier after stroke2021

    • Author(s)
      Yan Haomin、Kanki Hideaki、Matsumura Shigenobu、Kawano Tomohiro、Nishiyama Kumiko、Sugiyama Shintaro、Takemori Hiroshi、Mochizuki Hideki、Sasaki Tsutomu
    • Journal Title

      Cell Death Discovery

      Volume: 7 Issue: 1 Pages: 380-380

    • DOI

      10.1038/s41420-021-00773-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15695, KAKENHI-PROJECT-21K07414
  • [Journal Article] Loss of CREB Coactivator CRTC1 in SF1 Cells Leads to Hyperphagia and Obesity by High-fat Diet But Not Normal Chow Diet2021

    • Author(s)
      Matsumura Shigenobu、Ishikawa Fuka、Sasaki Tsutomu、Terkelsen Mike Krogh、Ravnskjaer Kim、Jinno Tomoki、Tanaka Jin、Goto Tsuyoshi、Inoue Kazuo
    • Journal Title

      Endocrinology

      Volume: 162 Issue: 9

    • DOI

      10.1210/endocr/bqab076

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H02909
  • [Journal Article] Cerebral microbleeds development after stroke thrombolysis: A secondary analysis of the THAWS randomized clinical trial2021

    • Author(s)
      Kaori Miwa, Masatoshi Koga, Manabu Inoue, Sohei Yoshimura, Makoto Sasaki, Yusuke Yakushiji, Mayumi Fukuda-Doi, Yasushi Okada, Taizen Nakase, Masafumi Ihara, Yoshinari Nagakane, Shunya Takizawa, Koko Asakura, Junya Aoki, Kazumi Kimura, Haruko Yamamoto, Kazunori Toyoda
    • Journal Title

      Int J Stroke

      Volume: - Issue: 6 Pages: 628-636

    • DOI

      10.1177/17474930211035023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09084, KAKENHI-PROJECT-20K12707, KAKENHI-PROJECT-21K17241
  • [Journal Article] CREB coactivator CRTC2 plays a crucial role in endothelial function.2020

    • Author(s)
      Kanki H, Sasaki T, Matsumura S, Kawano T, Todo K, Okazaki S, Nishiyama K, Takemori H, Mochizuki H.
    • Journal Title

      Journal of Neuroscience

      Volume: 40 (49) Issue: 49 Pages: 9533-9546

    • DOI

      10.1523/jneurosci.0407-20.2020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08867, KAKENHI-PROJECT-18K19174
  • [Journal Article] Chronic high corticosterone with voluntary corn oil ingestion induces significant body weight gain in mice2019

    • Author(s)
      Matsumura Shigenobu、Odanaka Mayuki、Ishikawa Fuka、Sasaki Tsutomu、Manio Mark Christian C.、Fushiki Tohru、Inoue Kazuo
    • Journal Title

      Physiology & Behavior

      Volume: 204 Pages: 112-120

    • DOI

      10.1016/j.physbeh.2019.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04924
  • [Journal Article] β-arrestin-2 in PAR-1-biased signaling has a crucial role in endothelial function via PDGF-β in stroke2019

    • Author(s)
      Kanki Hideaki、Sasaki Tsutomu、Matsumura Shigenobu、Yokawa Satoru、Yukami Toshiro、Shimamura Munehisa、Sakaguchi Manabu、Furuno Tadahide、Suzuki Takahiro、Mochizuki Hideki
    • Journal Title

      Cell Death & Disease

      Volume: 10 Issue: 2 Pages: 1375-1380

    • DOI

      10.1038/s41419-019-1375-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04924
  • [Journal Article] A 9-Year Longitudinal Study of Basilar Artery Diameter2019

    • Author(s)
      Takeuchi M, Miwa K, Tanaka M, Zhou Y, Todo K, Sasaki T, Sakaguchi M, Kitagawa K, Mochizuki H.
    • Journal Title

      J Am Heart Assoc.

      Volume: 8 Issue: 5

    • DOI

      10.1161/jaha.118.011154

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09084
  • [Journal Article] New 5-Aryl-Substituted 2-Aminobenzamide-Type HDAC Inhibitors with a Diketopiperazine Group and Their Ameliorating Effects on Ischemia-Induced Neuronal Cell Death.2018

    • Author(s)
      Hirata Y, Sasaki T, Kanki H, Choong CJ, Nishiyama K, Kubo G, Hotei A, Taniguchi M, Mochizuki H, Uesato S.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 1400-1400

    • DOI

      10.1038/s41598-018-19664-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05700, KAKENHI-PROJECT-17F17413, KAKENHI-PROJECT-16K15317
  • [Journal Article] Voluntary Corn Oil Ingestion Increases Energy Expenditure and Interscapular UCP1 Expression Through the Sympathetic Nerve in C57BL/6 Mice2018

    • Author(s)
      Matsumura Shigenobu、Ishikawa Fuka、Sasaki Tsutomu、Odanaka Mayuki、Manio Mark Christian C.、Fushiki Tohru、Inoue Kazuo
    • Journal Title

      Molecular Nutrition & Food Research

      Volume: 62 Issue: 22 Pages: 1800241-1800241

    • DOI

      10.1002/mnfr.201800241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04924
  • [Journal Article] Plasma D-dimer levels and ischaemic lesions in multiple vascular regions can predict occult cancer in patients with cryptogenic stroke.2017

    • Author(s)
      Gon Y, Sakaguchi M, Takasugi J, Kawano T, Kanki H, Watanabe A, Oyama N, Terasaki Y, Sasaki T, Mochizuki H.
    • Journal Title

      Eur J Neurol.

      Volume: Mar;24(3) Issue: 3 Pages: 503-508

    • DOI

      10.1111/ene.13234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Journal Article] Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner2017

    • Author(s)
      Honorat Josephe A.、Nakatsuji Yuji、Shimizu Mikito、Kinoshita Makoto、Sumi-Akamaru Hisae、Sasaki Tsutomu、Takata Kazushiro、Koda Toru、Namba Akiko、Yamashita Kazuya、Sanda Eri、Sakaguchi Manabu、Kumanogoh Atsushi、Shirakura Takashi、Tamura Mizuho、Sakoda Saburo、Mochizuki Hideki、Okuno Tatsusada
    • Journal Title

      PLoS One

      Volume: 12 Issue: 11 Pages: e0187215-e0187215

    • DOI

      10.1371/journal.pone.0187215

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09339, KAKENHI-PROJECT-16K15317
  • [Journal Article] Potential Application of 5-Aryl-Substituted 2-Amino- benzamide Type of HDAC1/2-Selective Inhibitors to Pharmaceuticals.2016

    • Author(s)
      Uesato S, Hirata Y, Sasaki T.
    • Journal Title

      Current Pharmaceutical Design

      Volume: 22, Dec Issue: 40 Pages: 6149-6159

    • DOI

      10.2174/1381612822666161208143417

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Journal Article] Characteristics of cryptogenic stroke in cancer patients2016

    • Author(s)
      Gon Y, Okazaki S, Terasaki Y, Sasaki T, Yoshimine T, Sakaguchi M, Mochizuki H.
    • Journal Title

      Ann Clin Transl Neurol.

      Volume: Feb 11;3(4) Issue: 4 Pages: 280-7

    • DOI

      10.1002/acn3.291

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Journal Article] Discovery of new low-molecular-weight p53-Mdmx disruptors and their anti-cancer activities2016

    • Author(s)
      Uesato, S.; Matsuura, Y.; Matsue, S.; Sumiyoshi, T.; Hirata, Y.; Takemoto, S.; Kawaratani, Y.; Yamai, Y.; Ishida, K.; Sasaki, T.; Enari, M.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 24 Issue: 8 Pages: 1919-1926

    • DOI

      10.1016/j.bmc.2016.03.021

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18903, KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-16K15317
  • [Journal Article] A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease.2016

    • Author(s)
      Choong CJ, Sasaki T, Hayakawa H, Yasuda T, Baba K, Hirata Y, Uesato S, Mochizuki H.
    • Journal Title

      Neurobiology of Aging

      Volume: 37 Pages: 103-116

    • DOI

      10.1016/j.neurobiolaging.2015.10.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01558, KAKENHI-PROJECT-24390222
  • [Journal Article] Association between cerebral small vessel diseases and mild parkinsonian signs in the elderly with vascular risk factors.2016

    • Author(s)
      Hatate J, Miwa K, Matsumoto M, Sasaki T, Yagita Y, Sakaguchi M, Kitagawa K, Mochizuki H.
    • Journal Title

      Parkinsonism Relat Disord.

      Volume: Feb 13. pii: S1353-8020(16) Pages: 30039-6

    • DOI

      10.1016/j.parkreldis.2016.02.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-15K19227
  • [Journal Article] Serine racemase inhibition induces nitric oxide-mediated neurovascular protection during cerebral ischemia2016

    • Author(s)
      Watanabe A, Sasaki T, Kanki H, Yukami T, Takemori H, Sakaguchi M, Kitagawa K, Mochizuki H
    • Journal Title

      Neuroscience

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Journal Article] Chronic Elevation of Tumor Necrosis Factor-α Mediates the Impairment of Leptomeningeal Arteriogenesis in db/db Mice.2015

    • Author(s)
      Yukami T, Yagita Y, Sugiyama Y, Oyama N, Watanabe A, Sasaki T, Sakaguchi M, Mochizuki H, Kitagawa K.
    • Journal Title

      Stroke

      Volume: 46 Issue: 6 Pages: 1657-63

    • DOI

      10.1161/strokeaha.114.008062

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04844, KAKENHI-PROJECT-24390222
  • [Journal Article] Granulocyte colony-stimulating factor fails to enhance leptomeningeal collateral growth in spontaneously hypertensive rats2014

    • Author(s)
      Sugiyama Y, Yagita Y, Yukami T, Watanabe A, Oyama N, Terasaki Y, Omura-Matsuoka E, Sasaki T, Mochizuki H, Kitagawa K
    • Journal Title

      Neurosci Lett

      Volume: 564 Pages: 16-20

    • DOI

      10.1016/j.neulet.2014.01.053

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390234, KAKENHI-PROJECT-24591260, KAKENHI-PROJECT-24390222
  • [Journal Article] Altered Actions of Memantine and NMDA-Induced Currents in a New Grid2-Deleted Mouse Line.2014

    • Author(s)
      Ayako Kumagai, Akira Fujita, Tomoki Yokoyama, Yuki Nonobe, Yasuhiro Hasaba, Tsutomu Sasaki, Yumi Itoh, Minako Koura, Osamu Suzuki, Shigeki Adachi, Haruko Ryo, Arihiro Kohara, Lokesh P. Tripathi, Masato Sanosaka, Toshiki Fukushima, Taisei Nomura, Hiroshi Takemori, et al.
    • Journal Title

      Genes

      Volume: 5 Issue: 4 Pages: 1095-1114

    • DOI

      10.3390/genes5041095

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23241023, KAKENHI-PROJECT-25430186, KAKENHI-PROJECT-25670155, KAKENHI-PROJECT-25740023, KAKENHI-PROJECT-26430012, KAKENHI-PROJECT-26670196, KAKENHI-PROJECT-24390222
  • [Journal Article] Functional deterioration of endothelial nitric oxide synthase after focal cerebral ischemia2013

    • Author(s)
      Yagita Y, Kitagawa K, Oyama N, Yukami T, Watanabe A, Sasaki T, Mochizuki H
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 33 Issue: 10 Pages: 1532-9

    • DOI

      10.1038/jcbfm.2013.112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390234, KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-24591260
  • [Journal Article] CREB activation is a key player for ischemic tolerance in the brain2012

    • Author(s)
      Kitagawa K, Sasaki T, Terasaki Y, Yagita Y, Mochizuki H
    • Journal Title

      Rinsho Shinkeigaku

      Volume: 52(11) Pages: 904-7

    • NAID

      130004505204

    • Data Source
      KAKENHI-PROJECT-23390234
  • [Journal Article] Suppression of dynamin GTPase decreases alpha-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.2012

    • Author(s)
      Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A.
    • Journal Title

      Mol Neurodegener

      Volume: 7 Issue: 1 Pages: 38-38

    • DOI

      10.1186/1750-1326-7-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-23790974, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-24659423, KAKENHI-PUBLICLY-24111502
  • [Journal Article] CREB activation is a key player for ischemic tolerance in the brain .2012

    • Author(s)
      Kitagawa K, Sasaki T, et. al.
    • Journal Title

      Rinsho Shinkeigaku.

      Volume: 52(11) Pages: 904-2

    • NAID

      130004505204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Journal Article] A potent inhibitor of SIK2, 3,3',7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells2011

    • Author(s)
      A.Kumagai, N.Horike, Y.Satoh, H.Takemori, Y.Naeaoka, 他6名
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 10 Pages: 26148-26148

    • DOI

      10.1371/journal.pone.0026148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590131, KAKENHI-PROJECT-21591081
  • [Journal Article] Granulocyte colony-stimulating factor enhances arteriogenesis and amelioratescerebral damage in a mouse model of ischemic stroke.2011

    • Author(s)
      Sugiyama Y, Yagita Y, Sasaki T, et.al.
    • Journal Title

      Stroke

      Volume: 42(3) Pages: 770-775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Journal Article] SIK2 is a key regulator for neuronal survival after ischemia via TORC1-CREB2011

    • Author(s)
      Sasaki T, et.al.
    • Journal Title

      Neuron

      Volume: 69(1) Issue: 1 Pages: 106-119

    • DOI

      10.1016/j.neuron.2010.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081, KAKENHI-PROJECT-22591015
  • [Journal Article] Granulocyte colony-stimulating factor enhances arteriogenesis and ameliorates cerebral damage in a mouse model of ischemic stroke2011

    • Author(s)
      Sugiyama Y, Yagita Y, Oyama N, Terasaki Y, Omura-Matsua E, Sasaki T, Kitagawa K.
    • Journal Title

      Stroke

      Volume: 42(3) Issue: 3 Pages: 770-5

    • DOI

      10.1161/strokeaha.110.597799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081, KAKENHI-PROJECT-23390234
  • [Journal Article] SIK2 is a new key regulator for neuronal survival after ischemia through TORC1-CREB2011

    • Author(s)
      Sasaki T, Takemori H, Yagita Y, Terasaki Y, Uebi T, Horike N, Takagi H, Susumu T, Teraoka H, Kusano K, Hatano O, Oyama N, Sugiyama Y, Sakoda S, Kitagawa K.
    • Journal Title

      Neuron

      Volume: 13 ; 69(1) Pages: 106-19

    • URL

      http://dx.doi.org/10.1016/j.neuron.2010.12.004,

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Journal Article] SIK2 is a key regulator for neuronal survival after ischemia via TORC1-CREB.2011

    • Author(s)
      Sasaki T, et.al.
    • Journal Title

      Neuron

      Volume: 69(1) Pages: 106-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Journal Article] Cilostazol, not aspirin, reduces ischemic brain injury via endothelial protection in spontaneously hypertensive rats2011

    • Author(s)
      Oyama N, Yagita Y, et al
    • Journal Title

      Stroke

      Volume: 89 Issue: 9 Pages: 2571-2577

    • DOI

      10.1161/strokeaha.110.609834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591080, KAKENHI-PROJECT-21591081, KAKENHI-PROJECT-23390234
  • [Journal Article] An angiotensin II type 1 receptor blocker can preserve endothelial function and attenuate brain ischemic damage in spontaneously hypertensive rats.2010

    • Author(s)
      Oyama N, Yagita Y, Sasaki T, et al.
    • Journal Title

      J Neurosci Res

      Volume: 88(13) Pages: 2889-98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Journal Article] Activation of NR2A receptors induces ischemic tolerance through CREB signaling2010

    • Author(s)
      Terasaki Y, Sasaki T, et al.
    • Journal Title

      J Cereb Blood Flow & Metab (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Journal Article] Downregulation of SIK2 expression promotes the melanogenic program in mice2010

    • Author(s)
      Horike N, Kumagai A, Shimono Y, Onishi T, Itoh Y, Sasaki T, Kitagawa K, Hatano O, Takagi H, Susumu T, Teraoka H, Kusano K, Nagaoka Y, Kawahara H, Takemori H.
    • Journal Title

      Pigment Cell Melanoma Res

      Volume: 23(6) Issue: 6 Pages: 809-19

    • DOI

      10.1111/j.1755-148x.2010.00760.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Journal Article] Activation of NR2A receptors induces ischemic tolerance through CREB signaling2010

    • Author(s)
      Terasaki Y, Sasaki T, Yagita Y, Okazaki S, Sugiyama Y, Oyama N, Omura-ME, Sakoda S, Kitagawa K.
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 30 Issue: 8 Pages: 1441-1449

    • DOI

      10.1038/jcbfm.2010.18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Patent] 含窒素複素環誘導体、神経保護剤及びがん治療用医薬組成物2015

    • Inventor(s)
      佐々木勉、望月秀樹、Choong CJ、上里新一、住吉孝之
    • Industrial Property Rights Holder
      佐々木勉、望月秀樹、Choong CJ、上里新一、住吉孝之
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-09-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Patent] アシルアミノフェニル基を有する化合物及びその用途2015

    • Inventor(s)
      佐々木勉、望月秀樹、Choong CJ、上里新一、住吉孝之
    • Industrial Property Rights Holder
      佐々木勉、望月秀樹、Choong CJ、上里新一、住吉孝之
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-11-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Patent] アイソフォーム特異的新規 HDAC 阻害剤による神経疾患治療法の開発2014

    • Inventor(s)
      佐々木勉、望月秀樹、Choong CJ、上里新一、平田佳之
    • Industrial Property Rights Holder
      佐々木勉、望月秀樹、Choong CJ、上里新一、平田佳之
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-183239
    • Filing Date
      2014-09-09
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Patent] アシルアミノフェニル基を有する化合物及びその用途2014

    • Inventor(s)
      佐々木勉、望月秀樹、Choong CJ、上里新一
    • Industrial Property Rights Holder
      佐々木勉、望月秀樹、Choong CJ、上里新一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-237826
    • Filing Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Patent] 新規含窒素複素環誘導体2014

    • Inventor(s)
      上里新一、住吉孝明、平田佳之、望月秀樹、佐々木 勉
    • Industrial Property Rights Holder
      上里新一、住吉孝明、平田佳之、望月秀樹、佐々木 勉
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-183235
    • Filing Date
      2014-09-09
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] Effect of salt-inducible kinase on Ca2+ oscillations in primar y neuronal cultures2024

    • Author(s)
      Sasaki T, Kanki H, Kawano T, Yan H, Ikegami T, NIshiyama K, Okazaki S, Todo K, Matsumura S, Nagano S, MOchizuki H
    • Organizer
      第65回日本神経学会総会
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] スフェロイド神経培養におけるCa2+振動に対する塩誘導性キナーゼSIKの影響2023

    • Author(s)
      佐々木勉、神吉秀明、河野友裕、西山久美子、久田素、松村成暢、 望月秀樹
    • Organizer
      第29回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] Mdmx plays a crucial role in neuronal damage after ischemic stroke.2022

    • Author(s)
      Yan Haomin, Sasaki Tsutomu, Kanki hideaki, Nishiyama Kumiko, Nagano Seiichi, Mochizuki Hideki
    • Organizer
      第28回遺伝子細胞治療学会学術集会(JSGCT2022)
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] The effect of occludin deficiency in Tight Junction in Blood Brain Barrier after stroke.2022

    • Author(s)
      Shintaro Sugiyama, Tsutomu Sasaki, Hiroo Tanaka, Yan Haomin, Takeshi Ikegami, Hideaki Kanki, Atsushi Tamura, Sachiko Tsukita, Hideki Mochizuki.
    • Organizer
      第63回日本神経学会総会
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] 急性期脳梗塞のHot topics. (シンポジウム)病理、基礎2022

    • Author(s)
      佐々木 勉
    • Organizer
      第41回日本画像医学会.
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] がん診断時の好中球/リンパ球比はがん診断から2年以内の脳梗塞発症を予測する2021

    • Author(s)
      佐々木勉、権泰史、河野友裕、岡崎周平、松村泰志、Huang Ao, 服部聡、藤堂謙一、望月 秀樹
    • Organizer
      Stroke 2022
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] The role of occludin in Tight Junction in Blood Brain Barrier after stroke2021

    • Author(s)
      Shintaro Sugiyama, Tsutomu Sasaki, Hiroo Tanaka, Yen Haomin, Hideaki Kanki, Atsushi Tamura, Sachiko Tsukita, Hideki Mochizuki
    • Organizer
      第62回日本神経学会総会.
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] 急性期脳梗塞のHot topics 基礎と病理2021

    • Author(s)
      佐々木 勉
    • Organizer
      第41回日本画像医学会 学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] Examination of regulation of expression of nAChR by TMEM35 after cerebral ischemia2021

    • Author(s)
      佐々木勉、Yan Haomin、神吉秀明、河野友裕、杉山慎太郎、松村成暢、望月秀樹
    • Organizer
      第62回日本神経学会総会.
    • Data Source
      KAKENHI-PROJECT-21K07414
  • [Presentation] 脳虚血時における分泌型Lynx1の動態の検討2018

    • Author(s)
      佐々木勉、神吉 秀明、松村 成暢、河野 友裕、上里 新一、坂口 学、望月秀樹
    • Organizer
      第43回日本脳卒中学会学術集会(STROKE 2018)
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Presentation] CRTC2 played important role for ischemic stroke2018

    • Author(s)
      Hideaki Kanki, Tsutomu Sasaki, Manabu Sakaguchi, Hideki Mochizuki
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Presentation] Screening for small-molecule inhibitors of protein-protein interaction (PPI) with neuroprotective effect in experimental PD2017

    • Author(s)
      Choong CJ, Sasaki T, Baba K, Hirata Y, Uesato S and Mochizuki H
    • Organizer
      The XXIII World Congress of Neurology (WCN 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Presentation] CRTC2 enhanced angiogenesis and endothelial function2017

    • Author(s)
      Hideaki Kanki, Tsutomu Sasaki, Manabu Sakaguchi, Hideki Mochizuki
    • Organizer
      The XXIII World Congress of Neurology (WCN 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Presentation] The mechanisms of neuroprotective effects of isoform selective HDAC inhibitors for brain ischemia.2017

    • Author(s)
      Sasaki T, Kanki H, Choong CJ, Baba K, Hirata Y, Sakaguchi M, Uesato S and Mochizuki H
    • Organizer
      The XXIII World Congress of Neurology (WCN 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Presentation] Small-molecule p53/negative regulator-interaction inhibitors confer neuroprotection against MPP+/MPTP-induced neurotoxicity in experimental PD2017

    • Author(s)
      Chi-Jing Choong, Tsutomu Sasaki, Hideki Hayakawa, Kousuke Baba, Yoshiyuki Hirata, Shinichi Uesato, and Hideki Mochizuki
    • Organizer
      Suzhou Basic Scientists Summer School 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15317
  • [Presentation] Selective inhibition of NR2B attenuates ischemic neuronal injury in neuronal culture and rats2016

    • Author(s)
      Terasaki Y, Sasaki T, Yukami T, Oyama N, Yagita Y, Sakaguchi M, Kitagawa K, Mochizuki H
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] Novel HDAC1/2 isoform-specific inhibitor K560 ameliorates MPP+/MPTP-mediated experimental Parkinson’s disease2016

    • Author(s)
      Chi-Jing Choong, Tsutomu Sasaki, Hideki Hayakawa, Toru Yasuda, Kousuke Baba, Yoshiyuki Hirata, Shinichi Uesato, and Hideki Mochizuki
    • Organizer
      AOPMC 2016 (5th Asian and Oceanian Parkinson’s Disease and Movement Disorders Congress)
    • Place of Presentation
      MANILA, PHILIPPINES
    • Year and Date
      2016-03-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] Serine racemase inhibition induces NO-mediated neurovascular protection during cerebral ischemia2016

    • Author(s)
      Watanabe A, Sasaki T, Kanki H, Yukami T, Takemori H, Sakaguchi M, Mochizuki H
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] Effect of thrombin and cAMP-PKA signaling on the angiogenesis in brain microvasculature2016

    • Author(s)
      Kanki H, Sasaki T, Watanabe A, Yukami T, Sakaguchi M, Mochizuki H
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] Efficacy and implications of isoform selective Histone deacetylase inhibitors for cerebral ischemia2016

    • Author(s)
      Sasaki T, Chonng Chi-Jing, Watanabe A, Kanki H, Yukami T, Hayakawa H, Yasuda T, Baba K, Sakaguchi M, Uesato S, Mochizuki H
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳虚血におけるSRR-Serineの役割について2015

    • Author(s)
      渡邊 彰弘、佐々木 勉、神吉 秀明、由上 登志郎、竹森 洋、坂口 学、望月 秀樹
    • Organizer
      第27回日本脳循環代謝学会総会
    • Place of Presentation
      富山
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease.2015

    • Author(s)
      Chi-Jing Choong, Tsutomu Sasaki, Hideki Hayakawa, Toru Yasuda, Kousuke Baba, Yoshiyuki Hirata, Shinichi Uesato, and Hideki Mochizuki
    • Organizer
      XXI World Congress on Parkinson’s Disease and Related Disorders. IAPRD 2015
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2015-12-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] Efficacy and implications of selective class I or II Histone deacetylase inhibitors for neurological disorders.2015

    • Author(s)
      CJ Choong, T Sasaki, H Hayakawa, K Baba, Watanabe A, Y Hirata, S Uesato and H Mochizuki
    • Organizer
      17th Annual Meeting of the American Society for Experimental NeuroTherapeutics (ASENT 2015)
    • Place of Presentation
      Georgetown University Hotel And Conference Center, District of Columbia, Washington, USA
    • Year and Date
      2015-02-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳虚血におけるPGC-1αシグナルの調節機構の検討2015

    • Author(s)
      佐々木 勉、渡邊 彰弘、神吉 秀明、由上 登志郎、竹森 洋、坂口 学、望月 秀樹
    • Organizer
      第27回日本脳循環代謝学会総会
    • Place of Presentation
      富山
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] アイソフォーム特異的HDAC阻害剤による虚血性脳血管障害の治療検討2015

    • Author(s)
      佐々木 勉、鐘 其静、渡邊 彰弘、神吉 秀明、馬場 孝輔、 平田 佳之、坂口 学、上里 新一、望月 秀樹
    • Organizer
      第33回日本神経治療学会総会 The 33rd Annual Meeting of Japanese Society of Neurological Therapeutics
    • Place of Presentation
      名古屋
    • Year and Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳虚血におけるCRTC-PGC-1αシグナルの動態についての検討2014

    • Author(s)
      佐々木 勉、 渡邊彰弘、 神吉秀明、 由上登志郎、 竹森 洋、 坂口 学、 望月秀樹
    • Organizer
      第51回日本臨床分子医学会総会
    • Place of Presentation
      東京国際フォーラム、東京都千代田区
    • Year and Date
      2014-04-11
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] ニコチン性アセチルコリン受容体活性化による神経保護作用の検討2014

    • Author(s)
      佐々木勉、北川一夫、渡邉彰弘、竹森 洋、渡邊 彰弘、由上登志郎、竹森 洋、望月秀樹
    • Organizer
      日本脳卒中学会(Stroke2014)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳虚血時のCRTC-PGC-1αシグナルの動態2014

    • Author(s)
      佐々木 勉、 北川一夫、 八木田佳樹、 由上登志郎、佐野坂真人、 八木田佳樹、 竹森 洋、 望月秀樹
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡国際会議場、福岡県福岡市博多区
    • Year and Date
      2014-05-21
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳虚血におけるCRTC-PGC-1αシグナルの動態についての検討2014

    • Author(s)
      佐々木勉、竹森 洋、渡邊 彰弘、由上登志郎、北川一夫、望月秀樹
    • Organizer
      臨床分子医学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 2型糖尿病では脳軟膜動脈吻合の発達は障害される2014

    • Author(s)
      由上登志郎、 八木田佳樹、渡邊彰弘、佐々木勉、坂口学、望月秀樹、北川一夫
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡国際会議場、福岡県福岡市博多区
    • Year and Date
      2014-05-21
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] Efficacy and implications of selective class I or II Histone deacetylase inhibitors for ischemic brain injury.2014

    • Author(s)
      Sasaki T, Choong CJ, Watanabe A, Hirata Y, Sanosaka M, Yukami T, Kitagawa K, Takemori H, Uesato S, Mochizuki H.
    • Organizer
      American Neurological Association's 2014 Annual Meeting
    • Place of Presentation
      Baltimore Marriott Waterfront Hotel, Maryland, USA
    • Year and Date
      2014-10-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳勝血管内皮細胞間接着結合に対する脳虚血の影響2013

    • Author(s)
      八木田佳樹, 北川一夫, 大山直記, 由上登志郎, 佐々木勉, 望月秀樹
    • Organizer
      第38回日本脳卒中学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390234
  • [Presentation] 脳側副血管発達に対する糖尿病の影響2013

    • Author(s)
      由上登志郎, 八木田佳樹, 佐々木勉, 望月秀樹, 北川一夫
    • Organizer
      第25回日本脳循環代謝学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23390234
  • [Presentation] A Role of CREB-CRTC signaling in nicotine-induced neuroprotection.2013

    • Author(s)
      T Sasaki, K Kitagawa, A Watanabe, T Yukami, N Oyama, Y Yagita, H Takemori, and H Mochizuki
    • Organizer
      Brain 2013
    • Place of Presentation
      Shanghai, China
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] ニコチンによる神経保護機構の検討2013

    • Author(s)
      佐々木勉、北川一夫、渡邊彰弘、 由上登志郎、八木田佳樹、竹森 洋 、望月秀樹
    • Organizer
      第54回日本神経学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 中枢神経系におけるCRTC-CREB制御機構とその役割2012

    • Author(s)
      佐々木勉
    • Organizer
      第24回日本脳循環代謝学会総会
    • Place of Presentation
      広島(招待講演)
    • Year and Date
      2012-11-08
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] ニコチンによるCREB活性化を介した神経保護機構の検討2012

    • Author(s)
      佐々木勉
    • Organizer
      第24回日本脳循環代謝学会総会
    • Place of Presentation
      広島
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 2型糖尿病モデルマウスにおける脳側副血管の発達についての検討2012

    • Author(s)
      由上登志郎、八木田佳樹、大山直紀、佐々木勉、望月秀樹、北川一夫
    • Organizer
      第24回日本脳循環代謝学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23390234
  • [Presentation] 脳虚血耐性時における塩誘導キナーゼ(SIK)-CRTC経路の意義2012

    • Author(s)
      佐々木勉
    • Organizer
      第53回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 高血圧自然発症ラットにおける脳軟膜動脈吻合の発達障害2012

    • Author(s)
      杉山幸生, 八木田佳樹, 大山直樹, 由上登志郎, 佐々木勉, 望月秀樹, 北川一夫
    • Organizer
      第37回日本脳卒中学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390234
  • [Presentation] A Role of CREB-CRTC signaling in nicotine-mediated neuroprotection2012

    • Author(s)
      Sasaki Tsutomu
    • Organizer
      Neuroscience2012(第35回日本神経科学会総会)
    • Place of Presentation
      Nagoya
    • Year and Date
      2012-09-18
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳虚血時における内因性保護シグナルの検討2012

    • Author(s)
      北川一夫、佐々木勉
    • Organizer
      第53回日本神経学会総会(招待講演)
    • Place of Presentation
      東京
    • Year and Date
      2012-05-23
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 脳虚血耐性時における塩誘導性キナーゼ(SIK)-CRTC経路の動態。2012

    • Author(s)
      佐々木勉
    • Organizer
      第53回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-24390222
  • [Presentation] 脳虚血後SIK2-TORC1-CREB経路の動態2011

    • Author(s)
      佐々木勉
    • Organizer
      第36回日本脳卒中学会総会(Stroke2011)
    • Place of Presentation
      京都
    • Year and Date
      2011-08-01
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] Implication of TORC1-CREB cascade in neuronal survival2011

    • Author(s)
      Sasaki T et al.
    • Organizer
      Brain 2011
    • Place of Presentation
      Barcelona(Spain)
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] Selective inhibition of NR2B-containing NMDAR attenuates neuronal Injury ofter OGD and in cortical neuron and permanent MCAO2011

    • Author(s)
      寺崎泰和、佐々木勉
    • Organizer
      American Stroke Association
    • Place of Presentation
      Los Angeles(USA)
    • Year and Date
      2011-02-11
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 塩誘導性キナーぜ(SIK2)によるTORC1-CREB経路を介する神経保護効果2011

    • Author(s)
      佐々木勉
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 脳虚血時におけるSIK-TORC1経路の意義2011

    • Author(s)
      佐々木勉
    • Organizer
      9th Future Forum Japan Symposium(招待講演)
    • Place of Presentation
      神戸
    • Year and Date
      2011-07-08
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 脳虚血後CaMKによるCRTC1-CREB制御機構に関する検討2011

    • Author(s)
      佐々木勉
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 神経細胞におけるニコチンによるCREB調節機構の検討2011

    • Author(s)
      佐々木勉
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 脳虚血時におけるSIK-TORC1経路の意義2011

    • Author(s)
      佐々木勉
    • Organizer
      9th Future Forum Japan Symposium
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2011-07-08
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] A role for SIK2-TORC1 cascade in neuronal survival after ischemia2010

    • Author(s)
      佐々木勉
    • Organizer
      Neuro 2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 脳虚血後CREB-CRE制御機構におけるbZIPドメインの重要性2010

    • Author(s)
      佐々木勉
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-23
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] 脳虚血後CREB-CRE制御におけるbZIPドメインの重要性2010

    • Author(s)
      佐々木勉
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-21591081
  • [Presentation] A role for SIK2-TORC1 cascade in neuronal survival after ischemia2010

    • Author(s)
      佐々木勉
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21591081
  • []

  • 1.  Matsumura Shigenobu (70467413)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 11 results
  • 2.  KITAGAWA Kazuo (70301257)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 24 results
  • 3.  nagaoka yasuo (90243039)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  YAGITA Yoshiki (20403066)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  takemori hiroshi (90273672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 6.  mochiduki hideki (90230044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 23 results
  • 7.  uesato shinnichi (50111969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  Kaori Miwa (80645341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  坂口 学 (70432474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  藤堂 謙一 (40403068)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  大山 直紀 (90622895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  高杉 純司 (40796033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  権 泰史 (70751311)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  平田 佳之 (00745854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 15.  田村 淳 (00362525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 16.  原田 直樹 (00529141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  西園 啓文 (10502289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OKUNO Tatsusada
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  NAKATSUJI Yuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  神吉 秀明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  長谷川 隆文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  武田 篤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  住吉 孝明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  梁 治子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  野村 大成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  横川 拓海
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  甲田 亨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  南波 明子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  山下 和哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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