Kitagawa Takao 北川孝雄

… Alternative Names

KITAGAWA Takao 北川孝雄

Less

Researcher Number	20614928
Other IDs	https://orcid.org/0000-0001-7753-827X
Affiliation (Current)	2025: 北海道医療大学, 先端研究推進センター, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 北海道医療大学, 先端研究推進センター, 助教 2023: 北海道医療大学, 先端研究推進センター, 講師 2017 – 2019: 山口大学, 大学院医学系研究科, 助教(特命) 2017: 山口大学, 大学院医学系研究科, 助教 2016: 山口大学, 医学(系)研究科(研究院), 助教(特命) 2013 – 2016: 山口大学, 医学(系)研究科(研究院), 助教 2014: 山口大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 50010:Tumor biology-related / Pediatric surgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Basic Section 48040:Medical biochemistry-related / Applied microbiology / Basic Section 57060:Surgical dentistry-related / Surgery of the organs maintaining homeostasis and related fields / Tumor therapeutics / General medical chemistry / General anatomy (including histology/embryology)
Keywords	Principal Investigator EWS-FLI1 / ユーイング肉腫 / ewing sarcoma / BioID / miniTurboID / AHDC1 / がん遺伝子 / 質量分析 / インタラクトーム解析 / 微生物 … More / 蛋白質 / 遺伝子 / 応用微生物 / 癌 / Yeast two-hybrid / 酵母 / プロテオミクス … More Except Principal Investigator メカノホメオスターシス / YAP / neurofibromatosis / interactome / proteomics / NF2 / NF1 / 神経線維腫症 / フィードバック / オルガノイド / プロテオミクス / 細胞外基質 / 再生 / 出芽酵母 / ターミネーター / 化合物スクリーニング / ゲノム編集 / 口腔潜在的悪性疾患 / CTGF / 数理モデル / 3次元臓器 / YAPメカノホメオスターシス / signaltransduction / NF遺伝子 / 分子標的 / シグナルネットワーク / multiomics / Proteomics / Neurofibromatosis / ネットワーク解析 / 融合プロテオミクス / インタラクトミクス / 臓器形成 / 立体臓器 / 時空間的ダイナミクス制御 / YAP メカノホメオスターシス / 力学恒常性 / ３次元培養 / 炎症性サイトカイン / 角強膜線維柱帯細胞 / 分子標的治療 / Bio-ID / 線維肉腫 / 癌の悪性化 / BioID / プログレッション / 悪性化 / 膵癌 / GLO1 / 発生医学 / 力学制御 / 臓器 / 三次元構築 / KTR プローブ / Hippoシグナル / RNA結合タンパク質 / 遺伝子発現 / 転写後発現制御 / 遺伝子発現制御 Less

Mechanistic analysis of pathogenesis by systems analysis of YAP activation dynamics regulation
- Principal Investigator
  
  清木誠
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Yamaguchi University
Development of Oral Epithelial Dysplasia Inhibitors Focusing on CTGF
- Principal Investigator
  
  堀江尚弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Elucidation of transcription control mechanism by the intrinsically disordered proteinsPrincipal Investigator
- Principal Investigator
  
  北川孝雄
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Health Sciences University of Hokkaido
Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of therapeutic strategies
- Principal Investigator
  
  荒木令江
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kumamoto University
Elucidation of molecular feedback mechanisms underlying mechano-homeostasis governing 3D organ formation and regeneration
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Yamaguchi University
Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of the therapeutic strategies
- Principal Investigator
  
  Araki Norie
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kumamoto University
Elucidation of an oncogenic mechanism that induced by the prion-like proteinsPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Takao
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Health Sciences University of Hokkaido
  Yamaguchi University
Mechanism of YAP control of whole organ mechanical property
- Principal Investigator
  
  SEIKI Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Yamaguchi University
The role of GLO1 in Cancer malignant progression
- Principal Investigator
  
  KURAMITSU Yasuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Health Sciences University of Hokkaido
A novel tissue culture system recapitulating in vivo physical properties
- Principal Investigator
  
  SEIKI MAKOTO
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
Analysis of gene regulartory network dynamics governing tissue mechanics
- Principal Investigator
  
  SEIKI Makoto
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Yamaguchi University
Identification of novel biding partners for oncogenes of Ewing sarcomaPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Takao
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Yamaguchi University
Elucidation of the molecular mechanism of action of the yeast strongest DIT1 terminator and its application
- Principal Investigator
  
  Matsuyama Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Toyota Central R&D Lab., Inc.
Elucidation of the molecular mechanism for highly active terminator regions in Saccharomyces cerevisiae
- Principal Investigator
  
  MATSUYAMA Takashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  Toyota Central R&D Lab., Inc.

All 2022 2019 2018 2017 2016 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells2022
- Author(s)
  Takao Kitagawa, Daiki Kobayashi, Byron Baron, Hajime Okita, Tatsuo Miyamoto, Rie Takai, Durga Paudel, Tohru Ohta, Yoichi Asaoka, Masayuki Tokunaga, Koji Nakagawa, Makoto Furutani-Seiki, Norie Araki, Yasuhiro Kuramitsu, Masanobu Kobayashi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 10 Pages: 0269077-0269077
- DOI
  10.1371/journal.pone.0269077
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06899, KAKENHI-PROJECT-22K10229, KAKENHI-PROJECT-21H02718, KAKENHI-PROJECT-19K07352, KAKENHI-PROJECT-20K21845, KAKENHI-PUBLICLY-20H05037, KAKENHI-PROJECT-19H03772, KAKENHI-PROJECT-22F22111
[Journal Article] Up‐regulation of the pentose phosphate pathway and HIF‐1α expression during neural progenitor cell induction following glutamate treatment in rat ex vivo retina2019
- Author(s)
  Tokuda Kazuhiro、Baron Byron、Yamashiro Chiemi、Kuramitsu Yasuhiro、Kitagawa Takao、Kobayashi Masaaki、Sonoda Koh‐Hei、Kimura Kazuhiro
- Journal Title
  
  Cell Biology International
  
  Volume: 44 Issue: 1 Pages: 137-144
- DOI
  10.1002/cbin.11212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-17K07218
[Journal Article] Optimization of fixative solution for retinal morphology: a comparison with Davidson’s fixative and other fixation solutions2018
- Author(s)
  Tokuda Kazuhiro、Baron Byron、Kuramitsu Yasuhiro、Kitagawa Takao、Tokuda Nobuko、Morishige Naoyuki、Kobayashi Masaaki、Kimura Kazuhiro、Nakamura Kazuyuki、Sonoda Koh-Hei
- Journal Title
  
  Japanese Journal of Ophthalmology
  
  Volume: 62 Issue: 4 Pages: 481-490
- DOI
  10.1007/s10384-018-0592-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00856, KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-17K11451, KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-16K11323
[Journal Article] CUB domain-containing protein 1 (CDCP1) was down-regulated by active hexose-correlated compound in human pancreatic cancer cells.2018
- Author(s)
  Kuhara K, Tokuda K, Kitagawa T, Baron B, Tokunaga M, Harada K, Terasaki M, Uehara O, Ohta T, Takai R, Hamada J, Kobayashi M, Shimo T, Nagayasu H, Kuramitsu Y.
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 11 Pages: 6107-6111
- DOI
  10.21873/anticanres.12961
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-16K07880, KAKENHI-PROJECT-16K11323
[Journal Article] Enzyme treated asparagus extract down-regulates heat shock protein 27 of pancreatic cancer cells.2018
- Author(s)
  Shimada T, Nanimoto Y, Baron B, Kitagawa T, Tokuda K, Kuramitsu Y.
- Journal Title
  
  In Vivo
  
  Volume: 32 Issue: 4 Pages: 759-763
- DOI
  10.21873/invivo.11305
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-16K11323
[Journal Article] Enzyme treated asparagus extract down-regulates heat shock protein 27 of pancreatic cancer cells.2018
- Author(s)
  Shimada T, Nanimoto Y, Baron B, Kitagawa T, Tokuda K, Kuramitsu Y.
- Journal Title
  
  IN VIVO
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07218
[Journal Article] PI3K inhibitor LY294002, as opposed to wortmannin, enhances AKT phosphorylation in gemcitabine-resistant pancreatic cancer cells.2017
- Author(s)
  Wang Y, Kuramitsu Y, Baron B, Kitagawa T, Tokuda K, Akada J, Maehara S, Maehara Y, Nakamura K.
- Journal Title
  
  Int J Oncol
  
  Volume: 50 Issue: 2 Pages: 606-612
- DOI
  10.3892/ijo.2016.3804
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07218
[Journal Article] Enhancement of protein production via the strong DIT1 terminator and two RNA-binding proteins in Saccharomyces cerevisiae.2016
- Author(s)
  Y. Ito, T. Kitagawa, M. Yamanashi, S. Katahira, S. Izawa, K. Irie, M. Furutani-Seiki, and T. Matsuyama
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 36997-36997
- DOI
  10.1038/srep36997
- NAID
  120007129256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26292039, KAKENHI-PROJECT-15K06944, KAKENHI-PROJECT-15K07378
[Journal Article] Characterization of five terminator regions that increase the protein yield of a transgene in Saccharomyces cerevisiae.2013
- Author(s)
  Ito Y, Yamanishi M, Ikeuchi A, Imamura C, Tokuhiro K, Kitagawa T, Matsuyama T.
- Journal Title
  
  Journal of Biotechnology
  
  Volume: 168 Issue: 4 Pages: 486-492
- DOI
  10.1016/j.jbiotec.2013.09.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25660071
[Patent] 酵母における外来遺伝子の高発現システム2014
- Inventor(s)
  松山崇、伊藤洋一郎、片平悟史、中村和行、北川孝雄
- Industrial Property Rights Holder
  豊田中央研究所、山口大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-007964
- Filing Date
  2014-01-20
- Data Source
  KAKENHI-PROJECT-25660071
[Presentation] The effect of ETASR50 on expression of heat shock protein 27 in pancreatic cancer cells.2018
- Author(s)
  Nanimoto Y, Shimada T, Baron B, Kitagawa T, Tokuda K, Kuramitsu Y.
- Organizer
  The 26th International Congress on Nutrition and Integrative Medicine, July 21-22, 2018, Sapporo
- Data Source
  KAKENHI-PROJECT-17K07218
[Presentation] DIT1ターミネーターと２つのRNA結合タンパク質による目的タンパク質の増産技術2018
- Author(s)
  松山崇、伊藤洋一郎、北川孝雄、山西守、片平悟史、井沢真吾、入江賢児、清木誠
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-15K07378
[Presentation] DIT1ターミネーターと２つのRNA結合タンパク質による目的タンパク質の増産技術2017
- Author(s)
  松山崇、伊藤洋一郎、北川孝雄、山西守、片平悟史、井沢真吾、入江賢児、清木誠
- Organizer
  日本生物工学会第69回大会
- Data Source
  KAKENHI-PROJECT-15K07378
[Presentation] 細胞壁合成阻害剤を用いたNAB6遺伝子の機能解析2016
- Author(s)
  松山崇、北川孝雄、入江賢児
- Organizer
  日本農芸化学会　2016年度大会
- Place of Presentation
  札幌コンベンションセンター、札幌市、北海道
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K07378
[Presentation] 出芽酵母のタンパク質発現量を2倍以上高めるDIT1ターミネーター2014
- Author(s)
  松山崇、伊藤洋一郎、山西守、池内暁紀、今村千絵、徳弘健郎、北川孝雄
- Organizer
  日本農芸化学会
- Place of Presentation
  明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-25660071
[Presentation] 出芽酵母の高活性ターミネーターDIT1tを活性化する遺伝子の同定
- Author(s)
  ○北川孝雄、伊藤洋一郎、片平悟史、倉満保宏、中村和行、松山崇
- Organizer
  酵母遺伝学フォーラム　第47回研究報告会
- Place of Presentation
  東京大学弥生講堂
- Year and Date
  2014-09-01 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-25660071

1. SEIKI Makoto (50226619)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. 浅岡洋一 (10436644)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. Araki Norie (80253722)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 古元礼子 (70311818)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. MATSUYAMA Takashi (90394882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 徳永雅之 (10845043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 田尾嘉誉 (30425417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 有賀隆行 (30452262)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 江良択実 (00273706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 武笠晃丈 (90463869)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. IRIE Kenji (90232628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. KURAMITSU Yasuhiro (50281811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 井沢真吾 (10273517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 吉野茂文 (60294633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 木村和博 (60335255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 浅井義之 (00415639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 尹浩信 (20282634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岡田眞里子 (10342833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 堀江尚弘 (30802318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 星和人 (30344451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 江草宏 (30379078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 志茂剛 (40362991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 疋田温彦 (60443397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 永易裕樹 (90265075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 福島聡 (50398210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 藤田美歌子 (00322256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 小林大樹 (20448517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 南部晶子 (40572087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 早野崇英 (30642392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 徳田信子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 蔵満保宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

Kitagawa Takao 北川 孝雄

KITAGAWA Takao 北川 孝雄

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of transcription control mechanism by the intrinsically disordered proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of an oncogenic mechanism that induced by the prion-like proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel biding partners for oncogenes of Ewing sarcomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells2022

Author(s)

Kitagawa Takao 北川孝雄

KITAGAWA Takao 北川孝雄