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Kitagawa Takao  北川 孝雄

… Alternative Names

KITAGAWA Takao  北川 孝雄

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Researcher Number 20614928
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7753-827X
Affiliation (Current) 2025: 北海道医療大学, 先端研究推進センター, 講師
Affiliation (based on the past Project Information) *help 2020 – 2024: 北海道医療大学, 先端研究推進センター, 助教
2023: 北海道医療大学, 先端研究推進センター, 講師
2017 – 2019: 山口大学, 大学院医学系研究科, 助教(特命)
2017: 山口大学, 大学院医学系研究科, 助教
2016: 山口大学, 医学(系)研究科(研究院), 助教(特命)
2013 – 2016: 山口大学, 医学(系)研究科(研究院), 助教
2014: 山口大学, 医学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related / Basic Section 50010:Tumor biology-related / Pediatric surgery
Except Principal Investigator
Basic Section 56010:Neurosurgery-related / Basic Section 48040:Medical biochemistry-related / Applied microbiology / Basic Section 57060:Surgical dentistry-related / Surgery of the organs maintaining homeostasis and related fields / Tumor therapeutics / General medical chemistry / General anatomy (including histology/embryology)
Keywords
Principal Investigator
EWS-FLI1 / ユーイング肉腫 / ewing sarcoma / BioID / miniTurboID / AHDC1 / がん遺伝子 / 質量分析 / インタラクトーム解析 / 微生物 … More / 蛋白質 / 遺伝子 / 応用微生物 / 癌 / Yeast two-hybrid / 酵母 / プロテオミクス … More
Except Principal Investigator
メカノホメオスターシス / YAP / neurofibromatosis / interactome / proteomics / NF2 / NF1 / 神経線維腫症 / フィードバック / オルガノイド / プロテオミクス / 細胞外基質 / 再生 / 出芽酵母 / ターミネーター / 化合物スクリーニング / ゲノム編集 / 口腔潜在的悪性疾患 / CTGF / 数理モデル / 3次元臓器 / YAPメカノホメオスターシス / signaltransduction / NF遺伝子 / 分子標的 / シグナルネットワーク / multiomics / Proteomics / Neurofibromatosis / ネットワーク解析 / 融合プロテオミクス / インタラクトミクス / 臓器形成 / 立体臓器 / 時空間的ダイナミクス制御 / YAP メカノホメオスターシス / 力学恒常性 / 3次元培養 / 炎症性サイトカイン / 角強膜線維柱帯細胞 / 分子標的治療 / Bio-ID / 線維肉腫 / 癌の悪性化 / BioID / プログレッション / 悪性化 / 膵癌 / GLO1 / 発生医学 / 力学制御 / 臓器 / 三次元構築 / KTR プローブ / Hippoシグナル / RNA結合タンパク質 / 遺伝子発現 / 転写後発現制御 / 遺伝子発現制御 Less
  • Research Projects

    (14 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (31 People)
  •  Mechanistic analysis of pathogenesis by systems analysis of YAP activation dynamics regulation

    • Principal Investigator
      清木 誠
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Yamaguchi University
  •  Development of Oral Epithelial Dysplasia Inhibitors Focusing on CTGF

    • Principal Investigator
      堀江 尚弘
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Elucidation of transcription control mechanism by the intrinsically disordered proteinsPrincipal Investigator

    • Principal Investigator
      北川 孝雄
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of therapeutic strategies

    • Principal Investigator
      荒木 令江
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Kumamoto University
  •  Elucidation of molecular feedback mechanisms underlying mechano-homeostasis governing 3D organ formation and regeneration

    • Principal Investigator
      Seiki Makoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Yamaguchi University
  •  Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of the therapeutic strategies

    • Principal Investigator
      Araki Norie
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Kumamoto University
  •  Elucidation of an oncogenic mechanism that induced by the prion-like proteinsPrincipal Investigator

    • Principal Investigator
      KITAGAWA Takao
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Health Sciences University of Hokkaido
      Yamaguchi University
  •  Mechanism of YAP control of whole organ mechanical property

    • Principal Investigator
      SEIKI Makoto
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Yamaguchi University
  •  The role of GLO1 in Cancer malignant progression

    • Principal Investigator
      KURAMITSU Yasuhiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Health Sciences University of Hokkaido
  •  A novel tissue culture system recapitulating in vivo physical properties

    • Principal Investigator
      SEIKI MAKOTO
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Yamaguchi University
  •  Analysis of gene regulartory network dynamics governing tissue mechanics

    • Principal Investigator
      SEIKI Makoto
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Yamaguchi University
  •  Identification of novel biding partners for oncogenes of Ewing sarcomaPrincipal Investigator

    • Principal Investigator
      KITAGAWA Takao
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatric surgery
    • Research Institution
      Yamaguchi University
  •  Elucidation of the molecular mechanism of action of the yeast strongest DIT1 terminator and its application

    • Principal Investigator
      Matsuyama Takashi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied microbiology
    • Research Institution
      Toyota Central R&D Lab., Inc.
  •  Elucidation of the molecular mechanism for highly active terminator regions in Saccharomyces cerevisiae

    • Principal Investigator
      MATSUYAMA Takashi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      Toyota Central R&D Lab., Inc.

All 2022 2019 2018 2017 2016 2014 2013 Other

All Journal Article Presentation Patent

  • [Journal Article] AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells2022

    • Author(s)
      Takao Kitagawa, Daiki Kobayashi, Byron Baron, Hajime Okita, Tatsuo Miyamoto, Rie Takai, Durga Paudel, Tohru Ohta, Yoichi Asaoka, Masayuki Tokunaga, Koji Nakagawa, Makoto Furutani-Seiki, Norie Araki, Yasuhiro Kuramitsu, Masanobu Kobayashi
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 10 Pages: 0269077-0269077

    • DOI

      10.1371/journal.pone.0269077

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06899, KAKENHI-PROJECT-22K10229, KAKENHI-PROJECT-21H02718, KAKENHI-PROJECT-19K07352, KAKENHI-PROJECT-20K21845, KAKENHI-PUBLICLY-20H05037, KAKENHI-PROJECT-19H03772, KAKENHI-PROJECT-22F22111
  • [Journal Article] Up‐regulation of the pentose phosphate pathway and HIF‐1α expression during neural progenitor cell induction following glutamate treatment in rat ex vivo retina2019

    • Author(s)
      Tokuda Kazuhiro、Baron Byron、Yamashiro Chiemi、Kuramitsu Yasuhiro、Kitagawa Takao、Kobayashi Masaaki、Sonoda Koh‐Hei、Kimura Kazuhiro
    • Journal Title

      Cell Biology International

      Volume: 44 Issue: 1 Pages: 137-144

    • DOI

      10.1002/cbin.11212

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-17K07218
  • [Journal Article] Optimization of fixative solution for retinal morphology: a comparison with Davidson’s fixative and other fixation solutions2018

    • Author(s)
      Tokuda Kazuhiro、Baron Byron、Kuramitsu Yasuhiro、Kitagawa Takao、Tokuda Nobuko、Morishige Naoyuki、Kobayashi Masaaki、Kimura Kazuhiro、Nakamura Kazuyuki、Sonoda Koh-Hei
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 62 Issue: 4 Pages: 481-490

    • DOI

      10.1007/s10384-018-0592-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K00856, KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-17K11451, KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-16K11323
  • [Journal Article] CUB domain-containing protein 1 (CDCP1) was down-regulated by active hexose-correlated compound in human pancreatic cancer cells.2018

    • Author(s)
      Kuhara K, Tokuda K, Kitagawa T, Baron B, Tokunaga M, Harada K, Terasaki M, Uehara O, Ohta T, Takai R, Hamada J, Kobayashi M, Shimo T, Nagayasu H, Kuramitsu Y.
    • Journal Title

      Anticancer Research

      Volume: 38 Issue: 11 Pages: 6107-6111

    • DOI

      10.21873/anticanres.12961

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-16K07880, KAKENHI-PROJECT-16K11323
  • [Journal Article] Enzyme treated asparagus extract down-regulates heat shock protein 27 of pancreatic cancer cells.2018

    • Author(s)
      Shimada T, Nanimoto Y, Baron B, Kitagawa T, Tokuda K, Kuramitsu Y.
    • Journal Title

      In Vivo

      Volume: 32 Issue: 4 Pages: 759-763

    • DOI

      10.21873/invivo.11305

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-18K07199, KAKENHI-PROJECT-16K11323
  • [Journal Article] Enzyme treated asparagus extract down-regulates heat shock protein 27 of pancreatic cancer cells.2018

    • Author(s)
      Shimada T, Nanimoto Y, Baron B, Kitagawa T, Tokuda K, Kuramitsu Y.
    • Journal Title

      IN VIVO

      Volume: in press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07218
  • [Journal Article] PI3K inhibitor LY294002, as opposed to wortmannin, enhances AKT phosphorylation in gemcitabine-resistant pancreatic cancer cells.2017

    • Author(s)
      Wang Y, Kuramitsu Y, Baron B, Kitagawa T, Tokuda K, Akada J, Maehara S, Maehara Y, Nakamura K.
    • Journal Title

      Int J Oncol

      Volume: 50 Issue: 2 Pages: 606-612

    • DOI

      10.3892/ijo.2016.3804

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07218
  • [Journal Article] Enhancement of protein production via the strong DIT1 terminator and two RNA-binding proteins in Saccharomyces cerevisiae.2016

    • Author(s)
      Y. Ito, T. Kitagawa, M. Yamanashi, S. Katahira, S. Izawa, K. Irie, M. Furutani-Seiki, and T. Matsuyama
    • Journal Title

      Sci. Rep.

      Volume: 6 Issue: 1 Pages: 36997-36997

    • DOI

      10.1038/srep36997

    • NAID

      120007129256

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26292039, KAKENHI-PROJECT-15K06944, KAKENHI-PROJECT-15K07378
  • [Journal Article] Characterization of five terminator regions that increase the protein yield of a transgene in Saccharomyces cerevisiae.2013

    • Author(s)
      Ito Y, Yamanishi M, Ikeuchi A, Imamura C, Tokuhiro K, Kitagawa T, Matsuyama T.
    • Journal Title

      Journal of Biotechnology

      Volume: 168 Issue: 4 Pages: 486-492

    • DOI

      10.1016/j.jbiotec.2013.09.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25660071
  • [Patent] 酵母における外来遺伝子の高発現システム2014

    • Inventor(s)
      松山崇、伊藤洋一郎、片平悟史、中村和行、北川孝雄
    • Industrial Property Rights Holder
      豊田中央研究所、山口大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-007964
    • Filing Date
      2014-01-20
    • Data Source
      KAKENHI-PROJECT-25660071
  • [Presentation] The effect of ETASR50 on expression of heat shock protein 27 in pancreatic cancer cells.2018

    • Author(s)
      Nanimoto Y, Shimada T, Baron B, Kitagawa T, Tokuda K, Kuramitsu Y.
    • Organizer
      The 26th International Congress on Nutrition and Integrative Medicine, July 21-22, 2018, Sapporo
    • Data Source
      KAKENHI-PROJECT-17K07218
  • [Presentation] DIT1ターミネーターと2つのRNA結合タンパク質による目的タンパク質の増産技術2018

    • Author(s)
      松山崇、伊藤洋一郎、北川孝雄、山西守、片平悟史、井沢真吾、入江賢児、清木誠
    • Organizer
      日本農芸化学会2018年度大会
    • Data Source
      KAKENHI-PROJECT-15K07378
  • [Presentation] DIT1ターミネーターと2つのRNA結合タンパク質による目的タンパク質の増産技術2017

    • Author(s)
      松山崇、伊藤洋一郎、北川孝雄、山西守、片平悟史、井沢真吾、入江賢児、清木誠
    • Organizer
      日本生物工学会第69回大会
    • Data Source
      KAKENHI-PROJECT-15K07378
  • [Presentation] 細胞壁合成阻害剤を用いたNAB6遺伝子の機能解析2016

    • Author(s)
      松山崇、北川孝雄、入江賢児
    • Organizer
      日本農芸化学会 2016年度大会
    • Place of Presentation
      札幌コンベンションセンター、札幌市、北海道
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-15K07378
  • [Presentation] 出芽酵母のタンパク質発現量を2倍以上高めるDIT1ターミネーター2014

    • Author(s)
      松山崇、伊藤洋一郎、山西守、池内暁紀、今村千絵、徳弘健郎、北川孝雄
    • Organizer
      日本農芸化学会
    • Place of Presentation
      明治大学生田キャンパス
    • Data Source
      KAKENHI-PROJECT-25660071
  • [Presentation] 出芽酵母の高活性ターミネーターDIT1tを活性化する遺伝子の同定

    • Author(s)
      ○北川孝雄、伊藤洋一郎、片平悟史、倉満保宏、中村和行、松山崇
    • Organizer
      酵母遺伝学フォーラム 第47回研究報告会
    • Place of Presentation
      東京大学弥生講堂
    • Year and Date
      2014-09-01 – 2014-09-03
    • Data Source
      KAKENHI-PROJECT-25660071
  • 1.  SEIKI Makoto (50226619)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  浅岡 洋一 (10436644)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 3.  Araki Norie (80253722)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  古元 礼子 (70311818)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  MATSUYAMA Takashi (90394882)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  徳永 雅之 (10845043)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  田尾 嘉誉 (30425417)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  有賀 隆行 (30452262)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  江良 択実 (00273706)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  武笠 晃丈 (90463869)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  IRIE Kenji (90232628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  KURAMITSU Yasuhiro (50281811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  井沢 真吾 (10273517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  吉野 茂文 (60294633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  木村 和博 (60335255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  浅井 義之 (00415639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  尹 浩信 (20282634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  岡田 眞里子 (10342833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  堀江 尚弘 (30802318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  星 和人 (30344451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  江草 宏 (30379078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  志茂 剛 (40362991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  疋田 温彦 (60443397)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  永易 裕樹 (90265075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  福島 聡 (50398210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  藤田 美歌子 (00322256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  小林 大樹 (20448517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  南部 晶子 (40572087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  早野 崇英 (30642392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  徳田 信子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  蔵満 保宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results

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