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Abe Toshiya  阿部 俊也

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ABE Toshiya  阿部 俊也

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Researcher Number 20722028
Affiliation (Current) 2025: 九州大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help 2022 – 2025: 九州大学, 大学病院, 助教
2019 – 2020: 九州大学, 医学研究院, 共同研究員
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / 0901:Oncology and related fields
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related / Basic Section 50010:Tumor biology-related
Keywords
Principal Investigator
膵癌 / 個別化医療 / 遺伝子変異 / microbiome / Microbiome / 家族性膵癌 / 腫瘍免疫微小環境 / DDR関連遺伝子バリアント / 癌間質相互作用 / 腸内細菌叢 … More / 次世代シーケンシング (NGS) / 膵癌周囲微小環境 / 癌微小環境 / 転移 / NGS / 化学療法耐性 / オルガノイド … More
Except Principal Investigator
膵癌 / 癌関連線維芽細胞 / 膵星細胞 / 癌免疫微小環境 / 腫瘍免疫微小環境 / 樹状細胞 / 腫瘍免疫 / 腫瘍微小環境 / 癌間質相互作用 / 免疫療法 / 老化細胞 / シングルセル遺伝子発現解析 / 集学的個別化治療 / 治療の個別化 / 免疫治療 / 膵癌サブタイプ分類 / サブタイプ分類 / 個別化治療 / 免疫微小環境 / 肝転移 / 肝星細胞 / 神経内分泌経路 / 抗腫瘍免疫 / single cell RNA-sequence / 大腸癌 / 樹状細胞(DC) / scRNA-seq / 不均一性 / 腫瘍免疫サイクル / scRNAseq / 食道癌 / 腫瘍免疫療法 / Autophagy抑制 / 膵癌微小環境 / 膵癌間質 / CAF / Autophagy / オートファジー / Single Cell遺伝子発現解析 / エネルギー代謝 / Single Cell解析 / メタボロミクス解析 Less
  • Research Projects

    (9 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (16 People)
  •  CAFを標的とした癌免疫の再活性化メカニズムの解明

    • Principal Investigator
      白羽根 健吾
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  TIME誘導能に応じた膵癌サブタイプ分類と個別TIME改変を目指した新規治療戦略

    • Principal Investigator
      大内田 研宙
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  膵癌DDR関連遺伝子バリアントにおける癌間質相互作用を標的とした個別化医療の実現Principal Investigator

    • Principal Investigator
      阿部 俊也
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  膵癌免疫微小環境-神経内分泌ネットワークの解明による免疫抑制解除への挑戦

    • Principal Investigator
      坂井 寛
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  Elucidation of Metabolite Distribution in Pancreatic Cancer Stroma through Metabolomics and Single-Cell Analysis.

    • Principal Investigator
      TORATA Nobuhiro
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kyushu University
  •  Targeting Autophagy to Uncover Immunosuppressive Mechanisms and Develop Novel Therapies for Pancreatic Cancer

    • Principal Investigator
      TOMA Hiroki
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  Elucidating DC Dysfunction in the Esophageal Cancer TME using scRNA-seq and Strategies for Overcoming It

    • Principal Investigator
      MIYASAKA Yoshihiro
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Elucidation of the interaction between the pancreatic cancer-related microbiome and host gene mutations to achieve precision medicinePrincipal Investigator

    • Principal Investigator
      ABE Toshiya
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  Elucidation of Microbiome which is related to pancreatic carcinogenesis, metastasis using NGS and application to the treatmentPrincipal Investigator

    • Principal Investigator
      ABE Toshiya
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Kyushu University

All 2025 2024 2023

All Journal Article Presentation

  • [Journal Article] Identification of cold tumor induction-related markers in pancreatic cancer and the clinical implication of PCDH72025

    • Author(s)
      Mochida Yuki、Ohuchida Kenoki、Zhang Bo、Yamada Yutaka、Tsutsumi Chikanori、Kubo Akihiro、Oyama Koki、Shinkawa Tomohiko、Iwamoto Chika、Torata Nobuhiro、Abe Toshiya、Ideno Noboru、Ikenaga Naoki、Nakata Kohei、Oda Yoshinao、Nakamura Masafumi
    • Journal Title

      Journal of Cancer Research and Clinical Oncology

      Volume: 151 Issue: 2 Pages: 45-45

    • DOI

      10.1007/s00432-025-06095-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08777, KAKENHI-PROJECT-23K19636, KAKENHI-PROJECT-23KJ1748, KAKENHI-PROJECT-23K27461, KAKENHI-PROJECT-24K19321
  • [Journal Article] Combined Autophagy Inhibition and Dendritic Cell Recruitment Induces Antitumor Immunity and Enhances Immune Checkpoint Blockade Sensitivity in Pancreatic Cancer2024

    • Author(s)
      Oyama K、Nakata K、Tsutsumi C、Hayashi M、Zhang B、Mochida Y、Shinkawa T、Hirotaka K、Zhong P、Date S、Luo H、Kubo N、Ohuchida K、Onishi H、Morisaki T、Kuba K、Higashijima N、Yamada Y、Abe T、Ideno N、Koikawa K、Iwamoto C、Ikenaga N、Ohuchida K、Onishi H、Morisaki T、Kuba K、Oda Y、Nakamura M
    • Journal Title

      Cancer Research

      Volume: 84 Issue: 24 Pages: 4214-4232

    • DOI

      10.1158/0008-5472.can-24-0830

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H00480, KAKENHI-PROJECT-23K24422, KAKENHI-PROJECT-21K08712, KAKENHI-PROJECT-21K08906, KAKENHI-PROJECT-22K07235, KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-23KJ1748, KAKENHI-PROJECT-23K27673, KAKENHI-PROJECT-24K02215, KAKENHI-PROJECT-23K06653, KAKENHI-PROJECT-23K08073, KAKENHI-PROJECT-23K08132, KAKENHI-PROJECT-24K11869, KAKENHI-PROJECT-24K22147
  • [Journal Article] Intratumor Fusobacterium nucleatum promotes the progression of pancreatic cancer via the CXCL1‐CXCR2 axis2023

    • Author(s)
      Hayashi Masataka、Ikenaga Naoki、Nakata Kohei、Luo Haizhen、Zhong PingShan、Date Satomi、Oyama Koki、Higashijima Nobuhiro、Kubo Akihiro、Iwamoto Chika、Torata Nobuhiro、Abe Toshiya、Yamada Yutaka、Ohuchida Kenoki、Oda Yoshinao、Nakamura Masafumi
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 9 Pages: 3666-3678

    • DOI

      10.1111/cas.15901

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07171, KAKENHI-PROJECT-22K08694, KAKENHI-PROJECT-21K08779, KAKENHI-PROJECT-21K08780, KAKENHI-PROJECT-22K15560, KAKENHI-PROJECT-22KJ2429, KAKENHI-PROJECT-22H00480, KAKENHI-PROJECT-23K24183
  • [Presentation] 膵癌をhot tumorに誘導する遺伝子群の検討2024

    • Author(s)
      持田郁己、大内田研宙、孫紀和、片山直樹、堤親範、久野恭子、寅田信博、阿部俊也、池永直樹、仲田興平、中村雅史
    • Organizer
      第124回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K27461
  • [Presentation] Autophagy inhibition in pancreatic cancer cells augments anti-tumor immunotherapy via dendritic cell activation due to antigen accumulation2024

    • Author(s)
      Koki Oyama, Kohei Nakata, Chikanori Tsutsumi, Bo Zhang, Yuki Mochida, Kento Hirotaka, Naoki Ikenaga, Toshiya Abe, Noboru Ideno, Chika Iwamoto, Kenoki Ohuchida, Keiji Kuba and Masafumi Nakamura
    • Organizer
      55th American Pancreatic Association 2024 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07235
  • [Presentation] 膵癌をhot tumorに誘導する遺伝子群の検討2024

    • Author(s)
      持田郁己、大内田研宙、孫紀和、片山直樹、堤親範、久野恭子、寅田信博、阿部俊也、池永直樹、仲田興平、中村雅史
    • Organizer
      第124回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K07171
  • [Presentation] Combination of autophagy inhibition, DC induction, and LAG3 blockade induces potent antitumor immunity and therapeutic response in PDAC2024

    • Author(s)
      Koki Oyama, Kohei Nakata, Naoki Ikenaga, Chikanori Tsutsumi, Bo Zhang, Yuki Mochida, Kento Hirotaka, Toshiya Abe, Noboru Ideno, Chika Iwamoto, Kenoki Ohuchida, Keiji Kuba, Masafumi Nakamura
    • Organizer
      第83回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07235
  • 1.  佐田 政史 (10783508)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  森山 大樹 (70586859)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  田村 公二 (90909582)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TORATA Nobuhiro (00398075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  TOMA Hiroki (80437780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MIYASAKA Yoshihiro (40507795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  堀岡 宏平 (10783699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  坂井 寛 (80611665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  永吉 絹子 (90761015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  大内田 研宙 (20452708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  白羽根 健吾 (10529803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  小薗 真吾 (40706850)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  森崎 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  中村 雅史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  仲田 興平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  岩本 千佳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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