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TOMA Hiroki  当間 宏樹

ORCIDConnect your ORCID iD *help
Researcher Number 80437780
Affiliation (Current) 2021: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help 2015 – 2018: 九州大学, 医学研究院, 共同研究員
2012 – 2015: 九州大学, 医学(系)研究科(研究院), 共同研究員
2012: 九州大学, 医学研究院, 共同研究員
2011: 九州大学, 大学病院, 講師
2007 – 2010: 九州大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Digestive surgery
Except Principal Investigator
Digestive surgery / Tumor biology and related fields
Keywords
Principal Investigator
膵癌 / microRNA / miRNA / 膵臓外科学 / 治療抵抗性 / 膵液 / Gemcitabine / マイクロダイセクション / 癌間質相互作用 / エクソソーム … More / 脂肪組織由来幹細胞 / 癌関連線維芽細胞 / 活性化型膵星細胞 / High fat diet / 脂肪酸 / リノレン酸 / S100A4 / 膵周囲脂肪組織 … More
Except Principal Investigator
膵癌 / 癌間質相互作用 / 膵星細胞 / 膵臓外科学 / IPMN / mRNA / microRNA / オートファジー / 膵臓癌 / S100 family / LM04 / 電気化学チップ / テロメラーゼ / hTERT / FFPEサンプル / twist / Muc family / H-tert / S100P / S100A11 / 癌幹細胞 / セルソート / 治療抵抗性 / 間質幹細胞 / ニッチ / 間質細胞 / 癌間相互作用 / mRNA/microRNA / セルソーティング / 上皮間葉移行(EMT) / セルソーテング / 癌微小環境 / 膵癌間質細胞 / 抗間質薬 / ドラッグデリバリーシステム(DDS) / 化学療法抵抗性 / ナノカプセル / 抗繊維化薬 / 周皮細胞 / 血管リモデリング / 腫瘍血管 / 細胞外基質 / CD51 / PDAC / ADM / exosome / micro RNA / biomarker / バイオマーカー / エクソゾーム / miRNA / 膵液 / 膵前癌病変 / 早期診断 / 創薬 / オートファジー抑制剤 / 3Dバイオプリンター / オルガノイド / 微小環境 / 癌関連線維芽細胞 / 3Dバイオプリンター / 膵癌微小環境 / 基質リモデリング制御 Less
  • Research Projects

    (14 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (19 People)
  •  Novel method to visualize invasion and metastasis of pancreatic cancer using in vitro microenvironment model constructed by 3D bioprinter

    • Principal Investigator
      NAKAMURA Masafumi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Tumor biology and related fields
    • Research Institution
      Kyushu University
  •  Development of biomarkers target on exosomes which derived from stromal cells in premalignant microenvironment.

    • Principal Investigator
      MIYASAKA Yoshihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  New drug discovery screening targeting autophagy

    • Principal Investigator
      NAKATA Kohei
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Role of adipose tissue in pancreatic cancer local invasion as a component of tumor microenvironmentPrincipal Investigator

    • Principal Investigator
      TOMA Hiroki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Refractory cancer therapy development by cancer microenvironment elucidation and new drug delivery system based on autophagy

    • Principal Investigator
      NAGAI Eishi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Investigation of mechanisms about therapeutic resistance due to the difference of pancreatic stellate cell phenotypes and development of nano capsule including anti-stromal drugs

    • Principal Investigator
      MAEYAMA Ryo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  A new strategy in the treatment of pancreatic cancer focused on the tumor vessel remodeling by pericytes

    • Principal Investigator
      MANABE Tatsuya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  New development in the study of tumor-stromal interaction focused on extracellular miRNA via exosome.Principal Investigator

    • Principal Investigator
      TOMA Hiroki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Investigation the mechanism and the role of RNA activation by micro RNA in pancreatic cancer

    • Principal Investigator
      NAGAI Eishi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  General overview of research on diagnosis of pancreatic cancer using molecular makersinpancreaticjuiccandclinicalapPlicationofmolecularmakersondiagnosisofIPMNsubtype

    • Principal Investigator
      MIZUMOTO Kazihiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Prospective isolation of pancreatic cancer cells with highly malignant phenotype and development of future individualized therapy

    • Principal Investigator
      TANAKA Masao
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Identification of microRNA which is related to chemoresistance of pancreatic cancer, and intensification of the sensitivity by controlling the microRNA.Principal Investigator

    • Principal Investigator
      TOMA Hiroki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  膵癌幹細胞の同定とニッチの機能解析〜膵癌の治療抵抗性を克服するために

    • Principal Investigator
      水元 一博
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Gene expressions in microdissected target cells as the diagnostic markers of pancreatic cancer and the prediction of treatment outcome using nano-technology

    • Principal Investigator
      MIZUMOTO Kazuhiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University

All 2013 2012 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] Feasibility and safety of intracorporeal esophagojejunostomy after laparoscopic total gastrectomy: Inverted T-shaped anastomosis using linear staplers2013

    • Author(s)
      Nagai E, Ohuchida K, Nakata K, Toma H, Tanaka M
    • Journal Title

      Surgery

      Volume: 153(5) Pages: 732-8

    • Data Source
      KAKENHI-PROJECT-22390258
  • [Journal Article] The risk of lymph node metastasis in mucosal gastric carcinoma: especially for a mixture of differentiated and undifferentiated adenocarcinoma2012

    • Author(s)
      Nakata K, Nagai E, Ohuchida K, Ohtsuka T, Toma H, Tanaka M
    • Journal Title

      Hepatogastroenterology

      Volume: 59(118) Pages: 1855-8

    • Data Source
      KAKENHI-PROJECT-22390258
  • [Journal Article] Feasibility of laparoscopic gastrectomy for advanced gastric cancer with positive peritoneal cytology2012

    • Author(s)
      Yamanaka N, Nagai E, Ohuchida K, Ueda J, Toma H, Tanaka M
    • Journal Title

      Surg Today

    • NAID

      10031189764

    • Data Source
      KAKENHI-PROJECT-22390258
  • [Journal Article] Single-incision laparoscopy -assisted surgery for bowel obstruction: report of three cases2011

    • Author(s)
      Ohtsuka T, Nagai E, Toma H, Ohuchida K, Tanaka M
    • Journal Title

      Surg Today

      Volume: 41(11) Pages: 1519-23

    • NAID

      10030229390

    • Data Source
      KAKENHI-PROJECT-22390258
  • [Journal Article] Inhibition of p600 expression suppresses both invasiveness and anoikis resistance of gastric cancer2011

    • Author(s)
      Sakai H, Ohuchida K, Mizumoto K, Cui L, Nakata K, Toma H, Nagai E, Tanaka M
    • Journal Title

      Ann Surg Oncol

      Volume: 18(7) Pages: 2057-65

    • Data Source
      KAKENHI-PROJECT-22390258
  • [Journal Article] Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells2010

    • Author(s)
      Onimaru M, Ohuchida K, Egami T,Mizumoto K, Nagai E, Toma H, Tanaka M
    • Journal Title

      Cancer Gene Ther

      Volume: 17(8) Pages: 541-9

    • Data Source
      KAKENHI-PROJECT-22390258
  • [Journal Article] MircoRNA-2l modulates biological functions of pancreatic cacner cells including their proliferation, invasion and chemoresistance2009

    • Author(s)
      Moriyama T, Ohuchida K, Mizumoto K, Yu J, Sate N, Nabae T, Takahata S, Toma H, Nagai E and Tanaka M
    • Journal Title

      Molecular cancer therapeutics

      Volume: 8 Pages: 1067-1074

    • Data Source
      KAKENHI-PROJECT-21390380
  • [Presentation] 膵癌におけるCD133陽性細胞は、癌間質作用を介してより高い遊走・浸潤能を獲得する.2009

    • Author(s)
      森山大樹, 大内田研宙, 水元一博, 崔林, 余俊, 江上拓哉, 藤田逸人, 佐藤典宏, 当間宏樹, 永井英司, 田中雅夫
    • Organizer
      第109回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21390381
  • 1.  OHUCHIDA Kenoki (20452708)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 8 results
  • 2.  MIZUMOTO Kazuhiro (90253418)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 3 results
  • 3.  TOMINAGA Yohei (90304823)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  TANAKA Masao (30163570)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 5.  EISHI Nagai (30264021)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 6.  UEDA Junji (90529801)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 7.  MIYASAKA Yoshihiro (40507795)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  MAEYAMA Ryo (10611668)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  SATO Norihro (20423527)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 10.  EGAMI Takuya (40507787)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 11.  NAKATA Kohei (30419569)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  白羽根 健吾 (10529803)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  TKENAKA Shigeori (60188208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ONA Toshihiro (10346835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MANABE Tatsuya (60546464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NAKAMURA Masafumi (30372741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  高畑 俊一 (50437779)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  中山 功一 (50420609)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  森山 大樹 (70586859)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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