MIZUMOTO Kazuhiro 水元一博

Researcher Number	90253418
Other IDs
External Links
Affiliation (Current)	2020: 九州大学, 大学病院, 准教授
Affiliation (based on the past Project Information) *help	2007 – 2020: Kyushu University, Hospital, Cancer Center, Associate Professor 2003 – 2006: Kyushu University, Graduate School of Medical Sciences, Surgery and Oncology, 大学病院, 講師 2005: 九州大学, 病院, 講師 2002: Department of Surgery and Oncology, Graduate School of Medical Sciences, Assistant Professor, 医学部附属病院, 講師 2000 – 2001: Kyushu University, Assistant professor, 医学部・附属病院, 助手 1994 – 1999: 九州大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Digestive surgery / Medical systems / General surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery / Digestive surgery / Gastroenterology / Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / General surgery / Basic Section 53010:Gastroenterology-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 膵癌 / 膵星細胞 / テロメラーゼ / 癌間質相互作用 / 膵臓外科学 / IPMN / hTERT / mRNA / 治療抵抗性 / ニッチ … More Except Principal Investigator 膵癌 / 膵星細胞 / HGF / NK4 / 癌間質相互作用 / 遺伝子治療 / IPMN / microRNA / アデノウイルス / c-met / 浸潤 / 転移 / Pancreatic cancer / 癌微小環境 / GM-CSF / 膵臓外科学 / マイクロダイセクション / 治療抵抗性 / miRNA / 腫瘍免疫 / 間質細胞 / オートファジー / 腫瘍血管 / S100A4 / Helicobacter pylori / 腹膜播種 / 血管新生阻害 / Gene therapy / drug delivery system / Endo180 / 微小環境 / 膵癌オルガノイド / 小腸移植 / 拒絶反応 / トラフィッキング / ホーミング / IgA / 短腸症候群 / ホ-ミング / IFN-γ / MCP-1 / ハムスター / 胆嚢癌 / p53 / p21 / テロメラーゼ / アデノウイルスベクター / 腫瘍ワクチン / 腫瘍細切片 / 放射線照射 / MMP / MMP阻害剤 / 浸潤・転移 / c-Met / 遺伝子多型 / 相関解析 / 発がん感受性 / 膵液 / Gemcitabine / マクロファージ / 薬剤耐性 / ASC / ミクロベシクル / マイクロベシクル / ギャップジャンクション / 併存膵癌 / GNAS / 早期診断 / ペリサイト / 薬剤送達 / 血管内皮細胞 / 間質 / NG2 / PDGFRβ / 膵癌間質細胞 / 抗間質薬 / ドラッグデリバリーシステム(DDS) / 化学療法抵抗性 / ナノカプセル / 抗繊維化薬 / 周皮細胞 / 血管リモデリング / 細胞外基質 / CD51 / 治療耐性 / ウイルス / レンチウイルス / calpeptin / ramininα4 / MAL2遺伝子 / Nodal / HDAC1 / Sainomycin / Pirfenidone / ポックスウイルス / 胆嚢癌細胞 / 癌浸潤 / 線維芽細胞 / 肝細胞増殖因子 / プロテアーゼ / 胆嚢癌細胞株 / タンパク分解酵素 / gallbladder cancer cells / cancer invasion / proteolytic enzymes / fibroblasts / cancer-mesenchymal interaction / 胃悪性リンパ腫 / MALTリンパ腫 / 外科治療 / 胃全摘 / リンパ節郭清 / MALT型リンパ腫 / 臨床病理学 / 遺伝子解析 / 化学療法 / gastric malignant lymphoma / MALT lymphoma / surgical treatment / total gastrectomy / lymph node dissection / 胆道癌 / HGFアンタゴニスト / Cancer / Pancreas / Biliary tract / HGF antagonist / Invasion / Metastasis / Dissemination / MK4 / Angiogenesis inhibitor / Smad4 / Smad 4 / Inhibition of angiogenesis / ゲムシタビン / adenovirus / gene therapy / 遺伝子 / 診断 / 癌 / 臨床 / gene / pancreatic cancer / diagnosis / leading cells / 基質リモデリング / leading cell / 腹膜中皮細胞 / 湿潤・転移 / リモデリング / 膵臓癌 / 繊維芽細胞 / 播種 / 脂肪組織由来幹細胞 / 癌関連線維芽細胞 / 活性化型膵星細胞 / High fat diet / 脂肪酸 / リノレン酸 / 膵周囲脂肪組織 / 化合物ライブラリー / 間質標的治療 / 化合物スクリーニング / 脂肪滴 / MALDI-MSI / Energy Charge / 凍結組織アレイ / バイオマーカー検索 / バイオマーカー探索 / 膵オルガノイド / 腺房萎縮 / ADM / 局所浸潤 / Acinar atrophy / 膵腺房細胞 / 膵癌周囲微小環境 / ネオアンチゲン / がん微小環境 / 乳癌 / 腫瘍遺伝子変異量 / 腫瘍浸潤リンパ球 / 免疫チェックポイント阻害薬 / Tumor mutational burden / ペプチドがんワクチン療法 / 細胞死 / necroptosis / 細胞死形態 / desmoplasia / Pin1 / オルガノイド / ハイスループットスクリーニング / 大腸癌 / 大腸癌肝転移オルガノイド / シングルセル解析 / 腫瘍微小環境 / シングルセル発現解析 / 微小環境因子 / 膵癌subtype分類 Less

ヒト膵癌組織を使用した抗癌剤スクリーニングシステムの構築とその治療応用Ongoing
- Principal Investigator
  
  小薗真吾
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
PDX-3D法を用いた創薬ライブラリ構築と新規膵癌治療薬探索Principal InvestigatorOngoing
- Principal Investigator
  
  水元一博
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
大腸癌肝転移オルガノイドと単細胞解析を用いた微小環境改変に伴う治療抵抗機序の解明Ongoing
- Principal Investigator
  
  藤田逸人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
単一細胞解析とオルガノイドを用いた微小環境依存性に基づく膵癌subtype分類Ongoing
- Principal Investigator
  
  三好圭
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
膵癌微小環境によるAcinar atrophyの新機序と局所浸潤での役割の解明Ongoing
- Principal Investigator
  
  嶋本正弥
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyushu University
個別化精密がん免疫療法開発を目的とした腫瘍組織からのネオアンチゲン解析Ongoing
- Principal Investigator
  
  久保真
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
3D膵癌オルガノイドモデルを用いた新たな癌細胞死形態とそれに伴う浸潤機構の解明Ongoing
- Principal Investigator
  
  森山大樹
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Reproduction of the three dimensional coculture model reflecting pancreatic cancer microenvironment and metabolic analysis for the stromal remodeling by MALDI Mass-spectrometry Imaging.
- Principal Investigator
  
  SAKAI Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
The mechanism of invasion in pancreatic cancer cell - Identification and analysis of leading cells to invasion -
- Principal Investigator
  
  SHIMIZU Yukiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Relationship between stromal cells and pancreatic cancer cells in metastasis and dissemination
- Principal Investigator
  
  MORIYAMA Taiki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Role of adipose tissue in pancreatic cancer local invasion as a component of tumor microenvironment
- Principal Investigator
  
  TOMA Hiroki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of novel therapeutic agent targeting pancreatic cancer stroma by screening compound library
- Principal Investigator
  
  TOMINAGA Yohei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Induction of tumor-suppressing pancreatic stellate cell subpopulation by pancreatic cancer microenvironment reprogrammingPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Early detection of pancreatic ductal adenocarcinoma based on the molecular assessment of pancreatic ductal adenocarcinoma concomitant with IPMN of the pancreas.
- Principal Investigator
  
  OHTSUKA Takao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Normalization of tumor vessels targeting pericytes; a new approach in treatment of pancreatic cancer
- Principal Investigator
  
  SHIMAMOTO Masaya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Investigation of mechanisms about therapeutic resistance due to the difference of pancreatic stellate cell phenotypes and development of nano capsule including anti-stromal drugs
- Principal Investigator
  
  MAEYAMA Ryo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
A new strategy in the treatment of pancreatic cancer focused on the tumor vessel remodeling by pericytes
- Principal Investigator
  
  MANABE Tatsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
The improvement of therapy-resistance with modified new virus and application to the treatment in pancreatic cancer
- Principal Investigator
  
  EGAMI Takuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Biological and clinical significance of niche during carcinogenesis in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Identification of the key stromal cell responsible for desmoplasia of pancreatic cancer, elucidation of the origin of it, and regulation of its functionPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Functional analysis and regulation of microvesicles that affect tumor-stromal interaction in pancreatic cancer.
- Principal Investigator
  
  SHIMIZU Yukiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Identification of pancreatic stellate cell associated-microRNA that suppress tumor-stromal interaction and clarification of its mechanism.
- Principal Investigator
  
  TOMINAGA Yohei
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
A novel approach for early diagnosis and personalized therapy to pancreatic cancer by metabolic profilingPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Investigation the mechanism and the role of RNA activation by micro RNA in pancreatic cancer
- Principal Investigator
  
  NAGAI Eishi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Evaluating of a new role of mesenchymal cells for immunity in pancreatic cancer and new standard for treatment of pancreatic cancer by using the immunity
- Principal Investigator
  
  INOUE Shigetaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Role of autophagy in the chemoresistance in pancreatic cancer
- Principal Investigator
  
  OHTSUKA Takao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
General overview of research on diagnosis of pancreatic cancer using molecular makersinpancreaticjuiccandclinicalapPlicationofmolecularmakersondiagnosisofIPMNsubtypePrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
人工ウイルスを用いた新規早期ガン診断システムの構築Principal Investigator
- Principal Investigator
  
  水元一博
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Identification of microRNA which is related to chemoresistance of pancreatic cancer, and intensification of the sensitivity by controlling the microRNA.
- Principal Investigator
  
  TOMA Hiroki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
The expression and function analysis of microRNA in pancreatic cancer
- Principal Investigator
  
  SHUNICHI Takahata
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
膵癌幹細胞の同定とニッチの機能解析〜膵癌の治療抵抗性を克服するためにPrincipal Investigator
- Principal Investigator
  
  水元一博
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Gene expressions in microdissected target cells as the diagnostic markers of pancreatic cancer and the prediction of treatment outcome using nano-technologyPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
候補遺伝子アプローチによるIPMN感受性遺伝子のGENE-BASED相関検定
- Principal Investigator
  
  田中雅夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
表面増強ラマン分光法による膵液解析-新しい膵癌診断機器の開発へ向けてPrincipal Investigator
- Principal Investigator
  
  水元一博
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Kyushu University
Quantitative analysis of mRNA of Intraductal papillary mucinous neoplasms: To differentiate carcinoma from benign neoplasms
- Principal Investigator
  
  NAGAI Eishi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY
Tailor-made NK4-gene therapy for pancreatic cancer using nano devise.
- Principal Investigator
  
  TANAKA Masao
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of genetic diagnosis system for pancreatic cancer using modified telomeric repeat amplification protocols and electrochemical array chipPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY
放射線照射は癌浸潤を促進する-膵癌治療の新たな複合療法へむけて
- Principal Investigator
  
  田中雅夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Adenovirus-mediated Smad4 gene transfer inhibit.s tumor growth and metastasis of human pancreatic carcinoma
- Principal Investigator
  
  NAGAI Eishi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Treatment of pancreatic cancer by HGF antagonist, NK4, through new drug delivery system. -Approach from bench to practice
- Principal Investigator
  
  TANAKA Masao
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Anti-cancer chemoagents-triggered centrosome aberrance and its relationship with mitotic cell death in pancreatic cancer cells.Principal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Molecular diagnosis of pancreatic cancer by telomerasePrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY
胆嚢癌に対する遺伝子治療とテロメラーゼ測定の意義
- Principal Investigator
  
  小川尚洋
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
腫瘍細切片とGM-CSF遺伝子組換えアデノウイルスを用いた免疫遺伝子治療
- Principal Investigator
  
  田中雅夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
New strategy against pancteato-biliary carcinoma using NK4, a four-kringle antagonist of hepatocyte growth factor
- Principal Investigator
  
  TANAKA Masao
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
小腸移植の拒絶反応に対する新しいアプローチ：リンパ球トラフィッキングとホーミング
- Principal Investigator
  
  NAKAMURA Kenjiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
膵癌切除後のAdjuvant Cytokine Gene Therapy-ハムスター膵管癌を用いた基礎的研究-
- Principal Investigator
  
  TANAKA Masao
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
MECHANISTIC ANALYSIS AND ENHANCEMENT OF CELL DEATH OF HUMAN PANCREATIC CANCER CELL LINE EXPOSED BY HIGH DOSE X-RAY IRRADIATION - FOR THE IMPROVEMENT OF ADJUVANT CHEMOTHERPY OF PANCREATIC CANCERPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY
Mechanisms of invasion induced by hepatocyte growth factor in gallbladder carcinoma cell lines
- Principal Investigator
  
  SHIMURA Hideo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Analysis of malignant biology and gene disorder in gastric MALT lymphomas
- Principal Investigator
  
  SATOH Hiroshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
NECROSIS AND APORTOSIS OF HUMAN PANCREATIC CANCER CELL LINES-FOR THE IMPROVEMENT OF ADJUVANT CHEMOTHERAPY FOR PANCREATIC CANCERPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY

[Book] Annual Review 2014 消化器2014
- Author(s)
  佐田政史、水元一博、大内田研宙、大塚隆生、田中雅夫
- Total Pages
  306
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24390319
[Book] Annual Review 2014 消化器2014
- Author(s)
  佐田政史、水元一博、大内田研宙、大塚隆生、田中雅夫
- Total Pages
  306
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25670585
[Book] 分子生物学的研究に基づく膵癌の診断と治療臨床応用を目指して(総説)2011
- Author(s)
  藤田逸人, 大内田研宙, 水元一博, 田中雅夫
- Data Source
  KAKENHI-PROJECT-22591523
[Book] 【膵がん・膵内分泌腫瘍の最近の動向】膵がんの分子生物学的解析の現状(解説/特集)2011
- Author(s)
  大内田研宙, 藤田逸人, 水元一博, 田中雅夫
- Data Source
  KAKENHI-PROJECT-22591523
[Book] 【膵癌診療と研究の最先端】膵癌における癌間質相互作用(解説/特集)2011
- Author(s)
  大内田研宙, 大塚隆生, 水元一博, 田中雅夫
- Data Source
  KAKENHI-PROJECT-22591523
[Book] Pancreatic cancer; Methods and Protocols2005
- Author(s)
  Mizumoto K, Tanaka M
- Total Pages
  352
- Publisher
  Human Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390399
[Journal Article] CD110 promotes pancreatic cancer progression and its expression is correlated with poor prognosis.2019
- Author(s)
  Yan Z, Ohuchida K, Zheng B, Okumura T, Takesue S, Nakayama H, Iwamoto C, Shindo K, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Oda Y, Hashizume M, Nakamura M
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 145 Pages: 1147-1164
- DOI
  10.1007/s00432-019-02860-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10702, KAKENHI-PROJECT-18K07943, KAKENHI-PROJECT-17H06942, KAKENHI-PROJECT-16K10599, KAKENHI-PROJECT-17K19602, KAKENHI-PROJECT-17K16566, KAKENHI-PROJECT-18K16366
[Journal Article] Cancer-associated acinar-to-ductal metaplasia within the invasive front of pancreatic cancer contributes to local invasion.2019
- Author(s)
  Kibe S, Ohuchida K, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Koikawa K, Okumura T, Iwamoto C, Shindo K, Moriyama T, Nakata K, Miyasaka Y, Shimamoto M, Ohtsuka T, Mizumoto K, Oda Y, Nakamura M.
- Journal Title
  
  Cancer Lett.
  
  Volume: 444 Pages: 70-81
- DOI
  10.1016/j.canlet.2018.12.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07943, KAKENHI-PROJECT-18K16366, KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-17K19605, KAKENHI-PROJECT-17K10701
[Journal Article] Adipose tissue-derived stromal cells are sources of cancer-associated fibroblasts and enhance tumor progression by dense collagen matrix2019
- Author(s)
  Okumura T, Ohuchida K, Kibe S, Iwamoto C, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Koikawa K, Sada M, Horioka K, Mochidome N, Arita M, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Oda Y, Hashizume M, Nakamura M
- Journal Title
  
  International Journal of Cancer
  
  Volume: 144 Pages: 1401-1403
- DOI
  10.1002/ijc.31775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10700, KAKENHI-PROJECT-18K07943, KAKENHI-PROJECT-18K16366, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-16H05418, KAKENHI-PROJECT-18H02880, KAKENHI-PROJECT-17H06942, KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-17K19602, KAKENHI-INTERNATIONAL-15K21716
[Journal Article] Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo180.2018
- Author(s)
  Koikawa K, Ohuchida K, Takesue S, Ando Y, Kibe S, Nakayama H, Endo S, Abe T, Okumura T, Horioka K, Sada M, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Ohuchida R, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M.
- Journal Title
  
  Cancer Lett
  
  Volume: 412 Pages: 143-154
- DOI
  10.1016/j.canlet.2017.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-16K10599, KAKENHI-PROJECT-16K10601, KAKENHI-PROJECT-17K10700, KAKENHI-PROJECT-17K10701, KAKENHI-PROJECT-17K19607, KAKENHI-PROJECT-17K16563, KAKENHI-PROJECT-17K16566, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-15H04933, KAKENHI-PROJECT-16H06258, KAKENHI-PROJECT-16J03962, KAKENHI-PROJECT-15K09046, KAKENHI-PROJECT-15K10185, KAKENHI-PROJECT-15K10187, KAKENHI-PROJECT-15K10189, KAKENHI-PROJECT-16K19937, KAKENHI-ORGANIZER-26108001, KAKENHI-PROJECT-16K10600, KAKENHI-INTERNATIONAL-15K21716
[Journal Article] Visualizing Energy Charge in Breast Carcinoma Tissues by MALDI Mass-spectrometry Imaging Profiles of Low-molecular-weight Metabolites.2018
- Author(s)
  TORATA NOBUHIRO、KUBO MAKOTO、MIURA DAISUKE、OHUCHIDA KENOKI、MIZUUCHI YUSUKE、FUJIMURA YOSHINORI、HAYAKAWA EISUKE、KAI MASAYA、ODA YOSHINAO、MIZUMOTO KAZUHIRO、HASHIZUME MAKOTO、NAKAMURA MASAFUMI
- Journal Title
  
  Anticancer Res.
  
  Volume: 38 Pages: 4267-4272
- DOI
  10.21873/anticanres.12723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10699, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-16K10598, KAKENHI-INTERNATIONAL-15K21716, KAKENHI-PROJECT-17H03819
[Journal Article] Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination.2017
- Author(s)
  Abe T, Ohuchida K, Koikawa K, Endo S, Okumura T, Sada M, Horioka K, Zheng B, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 50 Pages: 457-467
- DOI
  10.3892/ijo.2016.3829
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05418, KAKENHI-PROJECT-16J03962, KAKENHI-PROJECT-26462063, KAKENHI-PROJECT-15K15498, KAKENHI-PROJECT-15K10185, KAKENHI-PROJECT-16K10599, KAKENHI-PROJECT-16K10600, KAKENHI-PROJECT-16K10602
[Journal Article] Autophagy inhibition enhances antiproliferative effect of salinomycin in pancreatic cancer cells.2017
- Author(s)
  Endo Sho、Nakata Kohei、Sagara Akiko、Koikawa Kazuhiro、Ando Yohei、Kibe Shin、Takesue Shin、Nakayama Hiromichi、Abe Toshiya、Okumura Takashi、Moriyama Taiki、Miyasaka Yoshihiro、Ohuchida Kenoki、Ohtsuka Takao、Mizumoto Kazuhiro、Nakamura Masafumi
- Journal Title
  
  Pancreatology
  
  Volume: 17 Pages: 990-996
- DOI
  10.1016/j.pan.2017.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-16K10598, KAKENHI-PROJECT-16K10601, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-15K10188, KAKENHI-PROJECT-15K10189, KAKENHI-PROJECT-16K15621
[Journal Article] Degree of desmoplasia in metastatic lymph node lesions is associated with lesion size and poor prognosis in pancreatic cancer patients. Oncol Lett.2017
- Author(s)
  Nakayama H, Ohuchida K, Yoshida M, Miyazaki T, Takesue S, Abe T, Endo S, Koikawa K, Okumura T, Moriyama T, Nakata K, Miyasaka Y, Shirahane K, Manabe T, Ohtsuka T, Toma H, Tominaga Y, Nagai E, Mizumoto K, Oda Y, Nakamura M.
- Journal Title
  
  Oncol Lett.
  
  Volume: 14 Pages: 3141-3147
- DOI
  10.3892/ol.2017.6549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-16K10598, KAKENHI-PROJECT-16K10600, KAKENHI-PROJECT-16K10602, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-16J03962
[Journal Article] Distinction of Invasive Carcinoma Derived From Intraductal Papillary Mucinous Neoplasms From Concomitant Ductal Adenocarcinoma of the Pancreas Using Molecular Biomarkers2016
- Author(s)
  Tamura K, Ohtsuka T, Date K, Fujimoto T, Matsunaga T, Kimura H, Watanabe Y, Miyazaki T, Ohuchida K, Takahata S, Ishigami K, Oda Y, Mizumoto K, Nakamura M, Tanaka M.
- Journal Title
  
  Pancreas
  
  Volume: 印刷中 Pages: 826-35
- DOI
  10.1097/mpa.0000000000000563
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293285, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010
[Journal Article] Overexpression of microRNA-5100 decreases the aggressive phenotype of pancreatic cancer cells by targeting PODXL2016
- Author(s)
  Chijiiwa Y, Moriyama T, Ohuchida K, Nabae T, Ohtsuka T, Miyasaka Y, Fujita H, Maeyama R, Manabe T, Abe A, Mizuuchi Y, Oda Y, Mizumoto K, Nakamura M
- Journal Title
  
  Int J Oncol.
  
  Volume: 48 Pages: 1499-1508
- DOI
  10.3892/ijo.2016.3389
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10185, KAKENHI-PROJECT-15K10186, KAKENHI-PROJECT-26462062, KAKENHI-PROJECT-26462064, KAKENHI-PROJECT-25461024, KAKENHI-PROJECT-25462117, KAKENHI-PROJECT-26670607, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010
[Journal Article] Suppression of CD51 in pancreatic stellate cells inhibits tumor growth by reducing stroma and altering tumor-stromal interaction in pancreatic cancer.2016
- Author(s)
  Horioka K, Ohuchida K, Sada M, Zheng B, Moriyama T, Fujita H, Manabe T, Ohtsuka T, Shimamoto M, Miyazaki T, Mizumoto K, Oda Y, Nakamura M.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 48 Pages: 1499-1508
- DOI
  10.3892/ijo.2016.3374
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10185, KAKENHI-PROJECT-15K10188, KAKENHI-PROJECT-26462063, KAKENHI-PROJECT-26462064, KAKENHI-PROJECT-15K19895, KAKENHI-PROJECT-15H04933, KAKENHI-PROJECT-25462116, KAKENHI-PROJECT-25462118, KAKENHI-PROJECT-26670607, KAKENHI-PROJECT-26861084, KAKENHI-PROJECT-26293305, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-15K09046
[Journal Article] Calpain inhibitor calpeptin suppresses pancreatic cancer by disrupting cancer-stromal interactions in a mouse xenograft model.2016
- Author(s)
  Yoshida M, Miyasaka Y, Ohuchida Kenoki, Okumura T, Zheng B, Torata N, Fujita H, Nabae T, Manabe T, Shimamoto M, Ohtsuka T, Mizumoto K, Nakamura M
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Pages: 1443-1452
- DOI
  10.1111/cas.13024
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-15H04933, KAKENHI-PROJECT-26293305, KAKENHI-PROJECT-26462063, KAKENHI-PROJECT-16K10599, KAKENHI-PROJECT-16K10600
[Journal Article] CD146 attenuation in cancer-associated fibroblasts promotes pancreatic cancer progression2016
- Author(s)
  Zheng B, ohuchida K, Chijiiwa Y, Zhao M, Mizuuchi Y, Cui L, Horioka K, Ohtsuka T, Mizumoto K, Oda Y, Hashizume M, Nakamura M, Tanaka M
- Journal Title
  
  Mol Carcinog
  
  Volume: - Pages: 1560-1572
- DOI
  10.1002/mc.22409
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-25462119, KAKENHI-PROJECT-26861084, KAKENHI-PROJECT-15H04933, KAKENHI-PROJECT-15K09046
[Journal Article] Predictive factors for the metachronous development of malignant lesions in the remnant pancreas after partial pancreatectomy for IPMN.2016
- Author(s)
  Miyasaka Y, Ohtsuka T, Tamura K, Mori Y, Shindo K, Yamada D, Takahata S, Ishigami K, Ito T, Tokunaga S, Oda Y, Mizumoto K, Nakamura M, Tanaka M.
- Journal Title
  
  Ann Surg
  
  Volume: 印刷中
- DOI
  10.1097/sla.0000000000001368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293285
[Journal Article] Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility.2016
- Author(s)
  Sada M, Ohuchida K, Horioka K, Okumura T, Moriyama T, Miyasaka Y, Ohtsuka T, Mizumoto K, Oda Y, Nakamura M
- Journal Title
  
  Cancer letter
  
  Volume: 372 Pages: 1499-1508
- DOI
  10.1016/j.canlet.2016.01.016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10185, KAKENHI-PROJECT-26462062, KAKENHI-PROJECT-26462063, KAKENHI-PROJECT-15K19895, KAKENHI-PROJECT-15H04933, KAKENHI-PROJECT-25461024, KAKENHI-PROJECT-25462117, KAKENHI-PROJECT-26670607, KAKENHI-PROJECT-26861084, KAKENHI-PROJECT-26293305, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-15K09046
[Journal Article] Clinical Significance of GNAS Mutation in Intraductal Papillary Mucinous Neoplasm of the Pancreas With Concomitant Pancreatic Ductal Adenocarcinoma2015
- Author(s)
  Ideno N, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Tamura K, Aso T, Aishima S, Miyasaka Y, Ohuchida K, Ueda J, Takahata S, Oda Y, Mizumoto K, Tanaka M
- Journal Title
  
  Pancreas
  
  Volume: 44 Pages: 311-320
- DOI
  10.1097/mpa.0000000000000258
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293285
[Journal Article] Predictors and diagnostic strategies for early-stage pancreatic ductal adenocarcinoma. A retrospective review2015
- Author(s)
  Kimura H, Ohtsuka T, Matsunaga T, Watanabe Y, Tamura K, Ideno N, Aso T, Miyazaki T, Osoegawa T, Aishima S, Miyasaka Y, Ueda J, Ushijima Y, Igarashi H, Ito T, Takahata S, Oda Y, Mizumoto K, Tanaka M.
- Journal Title
  
  Pancreas
  
  Volume: 44 Pages: 1148-1154
- DOI
  10.1097/mpa.0000000000000393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293285
[Journal Article] Assessment of Clonality of Multisegmental Main Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas Based on GNAS Mutation Analysis2015
- Author(s)
  Tamura K, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Ideno N, Aso T, Miyazaki T, Ohuchida K, Takahata S, Ito T, Ushijima Y, Oda Y, Mizumoto K, Tanaka M
- Journal Title
  
  Surgery
  
  Volume: 157 Pages: 277-284
- DOI
  10.1016/j.surg.2014.09.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293285
[Journal Article] CD166/ALCAM Expression Is Characteristic of Tumorigenicity and Invasive and Migratory Activities of Pancreatic Cancer Cells.2014
- Author(s)
  Fujiwara K, Ohuchida K, Sada M, Horioka K, Ulrich CD 3rd, Shindo K, Ohtsuka T, Takahata S, Mizumoto K, Oda Y, Tanaka M.
- Journal Title
  
  CD166/ALCAM expression is characteristic of tumorigenicity and invasive and migratory activities of pancreatic cancer cells
  
  Volume: 9 Pages: 1-11
- DOI
  10.1371/journal.pone.0107247
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J03692, KAKENHI-ORGANIZER-21103001, KAKENHI-PROJECT-24390318, KAKENHI-PROJECT-24390319, KAKENHI-PROJECT-24591014, KAKENHI-PROJECT-24591015, KAKENHI-PROJECT-24592031, KAKENHI-PROJECT-24592032, KAKENHI-PROJECT-25293285, KAKENHI-PROJECT-25461024, KAKENHI-PROJECT-25670585, KAKENHI-PROJECT-25670586, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-26293305, KAKENHI-PROJECT-26462063
[Journal Article] Peritoneal myofibroblasts at metastatic foci promote dissemination of pancreatic cancer2014
- Author(s)
  Akagawa S, Ohuchida K, Torata N, Hattori M, Eguchi D, Fujiwara K, Kozono S, Cui L, Ikenaga N, Ohtsuka T, Oishima S, Mizumoto K, Oda Y, Tanaka M
- Journal Title
  
  International Journal of Oncology
  
  Volume: 45 Pages: 113-120
- DOI
  10.3892/ijo.2014.2391
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390318, KAKENHI-PROJECT-24390319, KAKENHI-PROJECT-24591014, KAKENHI-PROJECT-24591015, KAKENHI-PROJECT-24592031, KAKENHI-PROJECT-24592032, KAKENHI-PROJECT-24791431, KAKENHI-PROJECT-25293285, KAKENHI-PROJECT-25461024, KAKENHI-PROJECT-25670585, KAKENHI-PROJECT-25670586, KAKENHI-PROJECT-25861198, KAKENHI-PROJECT-26293305, KAKENHI-PROJECT-26462063
[Journal Article] MicroRNA-373 is down regulated in pancreatic cancer and inhibits cancer cell incasion2014
- Author(s)
  Nakata K, Ohuchida K, Mizumoto K, Aishima S, Oda Y, Nagai E, Tanaka M
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 21
- DOI
  10.1245/s10434-014-3676-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390318, KAKENHI-PROJECT-24390319, KAKENHI-PROJECT-24591014, KAKENHI-PROJECT-24592031, KAKENHI-PROJECT-24592032, KAKENHI-PROJECT-24659615, KAKENHI-PROJECT-25293285, KAKENHI-PROJECT-25293287, KAKENHI-PROJECT-25461024, KAKENHI-PROJECT-25670585, KAKENHI-PROJECT-25670586, KAKENHI-PROJECT-25670587, KAKENHI-PROJECT-25713050, KAKENHI-PROJECT-26293305, KAKENHI-PROJECT-26462063, KAKENHI-PROJECT-26670607
[Journal Article] Role of pancreatic juice cytology in the preoperative management of intraductal papillary mucinous neoplasm of the pancreas in the era of international consensus guidelines 20122014
- Author(s)
  Ohtsuka T, Matsunaga T, KImura H, Watanabe Y, Tamura K, ideno N, Aso T, Miyasaka Y, Ueda J, Takahata S, Osoegawa T, Igarashi H, Ito T, Ushijima Y, Ookubo F, Oda Y, Mizumoto K, Tanaka M
- Journal Title
  
  World J Surg
  
  Volume: 38 Pages: 2994-3001
- DOI
  10.1007/s00268-015-2948-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293285
[Journal Article] Pancreatic Cancer: Clinical Significance of Biomarkers.2014
- Author(s)
  Mori M, Chiba T, Nakamizo A, Kumashiro R, Murata M, Akahoshi T, Tomikawa M, Ohuchida K, Ohtsuka T,Mizumoto K, Hashizume M,Tanaka M
- Journal Title
  
  GastroIntestinal Tumors
  
  Volume: 1 Pages: 33-40
- DOI
  10.1159/000354996
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21103001, KAKENHI-PROJECT-23390327, KAKENHI-PROJECT-24390318, KAKENHI-PROJECT-25282157, KAKENHI-PROJECT-25670585, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-26293305
[Journal Article] 【臨床検体から導き出す消化器病研究】膵液中バイオマーカーで膵疾患の診断、早期発見はできるか2014
- Author(s)
  大内田研宙、大塚隆生、水元一博、田中雅夫
- Journal Title
  
  分子消化器病
  
  Volume: 11 Pages: 42-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390319
[Journal Article] Migratory activity of CD105+ pancreatic cancer cells is strongly enhanced by pancreatic stellate cells2013
- Author(s)
  Kenji Fujiwara, Kenoki Ohuchida, Takao Ohtsuka, Kazuhiro Mizumoto, Koji Shindo, Naoki Ikenaga, Lin Cui, Shunichi Takahata, Shinichi Aishima, and Masao Tanak
- Journal Title
  
  Pancreas
  
  Volume: 42(8) Pages: 1283-90
- Data Source
  KAKENHI-PROJECT-23592012
[Journal Article] Elevated Expression Level of MicroRNA-196a Is Predictive of Intestinal-Type Intraductal Papillary Mucinous Neoplasm of the Pancreas2013
- Author(s)
  Aso T, Ohtsuka T, Tamura K, Ideno N, Kono H, Nagayoshi Y, Ohuchida K, Ueda J, Takahata S, Shindo K, Aishima S, Oda Y, Mizumoto K, Tanaka M.
- Journal Title
  
  Pancreas
  
  Volume: 43(3) Pages: 361-366
- Data Source
  KAKENHI-PROJECT-23592012
[Journal Article] MAL2 expression predicts distant metastasis and short survival in pancreatic cancer2013
- Author(s)
  Daiki Eguchi, Kenoki Ohuchida, Shingo Kozono, Naoki Ikenaga, Koji Shindo, Lin Cui, Kenji Fujiwara, Shin Akagawa, Takao Ohtsuka, Shunichi Takahata, Shoji Tokunaga, Kazuhiro Mizumoto, Masao Tanaka
- Journal Title
  
  Surgery
  
  Volume: 154(3) Pages: 573-82
- Data Source
  KAKENHI-PROJECT-23592012
[Journal Article] CD271 subpopulation of pancreatic stellate cells correlates with prognosis of pancreatic cancer and is regulated by interaction with cancer cells2012
- Author(s)
  Kenji Fujiwara, Kenoki Ohuchida, KazuhiroMizumoto, Koji Shindo, Daiki Eguchi,Shingo Kozono, Naoki Ikenaga, Takao Ohtsuka, Shunichi Takahata, Shinichi Aishima, Masao Tanaka
- Journal Title
  
  PLos One
  
  Volume: 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591523
[Journal Article] MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA gene2012
- Author(s)
  Ohuchida K, Mizumoto K, Nagai E, Tanaka M et al
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19(7) Pages: 2394-402
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] Senescence in intraductal papillary mucinous neoplasm of the pancreas2011
- Author(s)
  Miyasaka Y, Nagai E, Ohuchida K, Mizumoto K, Tsuneyoshi M, Tanaka M
- Journal Title
  
  Hum Pathol
  
  Volume: 42(12) Pages: 2010-7
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] Senescence in intraductal papillary mucinous neoplasm of the pancreas2011
- Author(s)
  Miyasaka Y, Nagai E, Ohuchida K, Fuijita H, Nakata K, Hayashi A, Mizumoto K, Tsuneyoshi M and Tanaka M
- Journal Title
  
  Human Pathology
  
  Volume: 42 Pages: 2010-17
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] Inhibition of p600 expression suppresses both invasiveness and anoikis resistance of gastric cancer2011
- Author(s)
  Sakai H, Ohuchida K, Mizumoto K, Cui L, Nakata K, Toma H, Nagai E, Tanaka M
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18(7) Pages: 2057-65
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] Expressionofclaudin・4(CLDN4) mRNAinintraductal papi■arymucinousneoplasmsofthe pancreas2011
- Author(s)
  TsutsumiK, SatoN, CuiL, MizumotoK, SadakariヱFujitaH, OhuchidaK, OhtsukaT, TakahataSandTanakaM
- Journal Title
  
  ModernPatholog
  
  Volume: 24 Pages: 533-541
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] Invasive carcinoma derived from intestinal type intraductal papillary mucinous neoplasm is associated with minimal invasion colloid carcinoma, and less invasisve behabiors, leading to better prognosis2011
- Author(s)
  Nakata K, Ohuchida K, Nagai E, Mizumoto K
- Journal Title
  
  Pancreas
  
  Volume: 40 Pages: 581-7
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] High EGFR mRNA expression is a prognostic factor for reduced survival in pancreaticcancer after gemcitabine-based adjuvant chemotherapy2011
- Author(s)
  Fujita H, Ohuchida K, Mizumoto K, Itaba S, Ita T, Nakata K, Yu J, Kayashima T, Hayashi A, Souzaki R, Tajiri T, Onimaru M, Manabe T, Ohtsuka T, Tanaka M.
- Journal Title
  
  International journal of oncology
  
  Volume: 38(3) Pages: 629-641
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] MicroRNA expression as a predictive marker for gemcitabine response after surgical resection of pancreatic cancer2011
- Author(s)
  Ohuchida K, Mizumoto K, Kayashima T, Ueda J, Nagai E, Tanaka M
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18(8) Pages: 2381-7
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] Invasive carcinoma derived from intestinal-type intraductal papillary mucinous neoplasm is associated with minimal invasion, colloid carcinoma, and less invasive behavior , leading to a better prognosis2011
- Author(s)
  Nakata K, Ohuchida K, Aishima S, Sadakari Y, Kayashima T, Miyasaka Y, Nagai E, Mizumoto K, Tanaka M
- Journal Title
  
  Pancreas
  
  Volume: 40(4) Pages: 581-7
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness and is correlated with a poor prognosis2011
- Author(s)
  Nakata K, Ohuchida K, Mizumoto K, Nagai E, Tanaka M
- Journal Title
  
  Surgery
  
  Volume: 150 Pages: 916-22
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] MicroRNA expression as a predictive marker for gemcitabine response after surgical resection of pancreatic cancer2011
- Author(s)
  Ohuchida K, Mizumoto K, Kayashima T, Fujita H, Moriyama T, Ohtsuka T, Ueda J, Nagai E, Hashizume M and Tanaka M
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18 Pages: 2381-2387
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] MicroRNA-2os expression as a new prognostic marker of pancreatic adenocarcinoma2010
- Author(s)
  Ikenaga N, Ohuchida K, Mizumoto K, Yu J, Kayashima T, Sakai H, Fujita H, Nakata K and Tanaka M
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 17 Pages: 3120-8
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells2010
- Author(s)
  Onimaru M, Ohuchida K, Egami T,Mizumoto K, Nagai E, Toma H, Tanaka M
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 17(8) Pages: 541-9
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] Invasive carcinoma derived from the nonintestinal type intraductal papillary mucinous neoplasm of the pancreas has a poorer prognosis than that derived from the intestinal type2010
- Author(s)
  Sadakari Y, Ohuchida K, Nakata K, Ohtsuka T, Aishima S, Takahata S, Nakamura M, Mizumoto K and Tanaka M
- Journal Title
  
  Surgery
  
  Volume: 147 Pages: 812-817
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] Combination with low-dose gemcitabine andhTERT-promoter-dependent conditionally replicative adenovirus enhances cytotoxicity through their crosstalk mechanisms in pancreatic cancer2010
- Author(s)
  Onimaru M, Ohuchida K, Nagai E,Mizumoto K, Egami T, Tanaka M
- Journal Title
  
  Cancer Lett
  
  Volume: 294(2) Pages: 178-86
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] MicroRNA, has-miR-2ooc, is an independent prognostic factor in pancreatic cancer and its up regulation inhibits pancreatic cancer invasion but increases cell proliferation2010
- Author(s)
  Ohuchida K, Mizumoto K, Fujita H, Nakata K and Tanaka M
- Journal Title
  
  Mol Cancer
  
  Volume: 9 Pages: 169-169
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] S100P is a novel marker to identify intraductal papillary mucinous neoplasms2010
- Author(s)
  Nakata K, Nagai E, Ohuchida K, Mizumoto K, Tanaka M
- Journal Title
  
  Hum Pathol
  
  Volume: 41(6) Pages: 824-31
- Data Source
  KAKENHI-PROJECT-22390258
[Journal Article] CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer2010
- Author(s)
  Naoki Ikenaga, Kenoki Ohuchida, Kazuhiro Mizumoto, Lin Cui, Tadashi Kayashima, Katsuya Morimatsu, Taiki Moriyama, Kohei Nakata, Hayato Fujita, Masao Tanaka
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 1041-1051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591523
[Journal Article] MicroRNA expression analyses in preoperative juice samples of pancreatic ductal adenocarcinoma2010
- Author(s)
  Sadakari Y, Ohtsuka T, Ohuchida K, Tsutsumi K, Takahata S, Nakamura M, Mizumoto K and Tanaka M
- Journal Title
  
  Jap
  
  Volume: 11 Pages: 587-92
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy2010
- Author(s)
  Fujita H, Ohuchida K, Mizumoto K, Itaba S, Ita T, Nakata K, Yu J, Kayashima T, Souzaki R, Tajiri T, Manabe T, Ohtsuka T and Tanaka M
- Journal Title
  
  Neoplasia
  
  Volume: 12 Pages: 807-817
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] SiooA4 mRNA is a diagnostic and prognostic marker in pancreatic carcinoma2009
- Author(s)
  Ikenaga N, Ohuchida K, Mizumoto K, Yu J, Fujita H, Nakata K, Ueda J, Sate N, Nagai E, Tanaka M
- Journal Title
  
  J Gastrointest Surg
  
  Volume: 13 Pages: 1852-1858
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] LMO2 is a novel predictive marker for a better prognosis in pancreatic cancer2009
- Author(s)
  0 Nakata K, Ohuchida K, Nagai E, Hayashi A, Miyasaka Y, Kayashima T, Yu J, Aishima S, Oda Y, Mizumoto K, Tanaka M and Tsuneyoshi M
- Journal Title
  
  Neoplasia
  
  Volume: 11 Pages: 712-719
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] MircoRNA-2l modulates biological functions of pancreatic cacner cells including their proliferation, invasion and chemoresistance2009
- Author(s)
  Moriyama T, Ohuchida K, Mizumoto K, Yu J, Sate N, Nabae T, Takahata S, Toma H, Nagai E and Tanaka M
- Journal Title
  
  Molecular cancer therapeutics
  
  Volume: 8 Pages: 1067-1074
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] MicroRNA-21(miR-21)modulates biologic functions of pancreatic cancercells including their proliferation, invasion andchemoresistance2009
- Author(s)
  Taiki Moriyama, Kenoki Ohuchida, KazuhiroMizumoto, Jun Yu, Norihiro Sato, ToshinagaNabae, Shunichi Takahata, Hiroki Toma, EishiNagai, Masao Tanaka
- Journal Title
  
  Molecular Cancer Therapeutics (in press)
- Data Source
  KAKENHI-PROJECT-19591592
[Journal Article] REG4 is associated with carcinogenesis in the intestinal pathway of intraductal papillary mucinous neoplasms of the pancreas2009
- Author(s)
  Nakata K, Nagai E, Ohuchida K, Aishima S, Hayashi A, Miyasaka Y, Yu J, Mizumoto K, Tanaka M and Tsuneyoshi M
- Journal Title
  
  Mod Pathol
  
  Volume: 24 Pages: 533-541
- Data Source
  KAKENHI-PROJECT-21390380
[Journal Article] Pancreatic cancer ; Methods and Protocols2005
- Author(s)
  K.Mizumoto, M.Tanaka, et al.
- Journal Title
  
  Human Press
  
  Pages: 199-205
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390399
[Journal Article] CD271 subpopulation of pancreatic stellate cells correlates with prognosis of pancreatic cancer and is regulated by interaction with cancer cells
- Author(s)
  Fujiwara K, Ohuchida K, Mizumoto K, Shindo K, Eguchi D, Kozono S, Ikenaga N, Ohtsuka T, Takahata S, Aishima S, Tanaka M.
- Journal Title
  
  PLoS One
  
  Volume: 7(12)
- Data Source
  KAKENHI-PROJECT-23592012
[Presentation] Necroptosis in Pancreatic Cancer Promotes Cancer Cell Migration and Invasion by Release of CXCL52019
- Author(s)
  Ando K, Ohuchida K, Otsubo Y, Sagara A, Kibe S, Takesue S, Nakayama M, Shindo K, Moriyama T, Nakata K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 50th Annual Meeting of the American Pancreatic Association(APA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07943
[Presentation] Necroptosis in Pancreatic Cancer Promotes Cancer Cell Migration and Invasion by Release of CXCL52019
- Author(s)
  Ando Y, Ohuchida K, Otsubo Y, Sagara A, Kibe S, Takesue S, Nakayama M, Shindo K, Moriyama T, Nakata K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 50th Annual Meeting of the American Pancreatic Association(APA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08708
[Presentation] 膵癌細胞のnecroptosisによって放出されるCXCL5は膵癌細胞の遊走・浸潤を促進する2019
- Author(s)
  安藤陽平, 大内田研宙, 相良亜希子, 米永晃子, 岐部晋, 武居晋, 中山宏道, 森山大樹, 仲田興平, 宮坂義浩, 大塚隆生, 水元一博, 中村雅史
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08708
[Presentation] Basement membrane destruction by pancreatic stellate cells leads to local invasion in pancreatic ductal adenocarcinoma2018
- Author(s)
  Koikawa K, Ohuchida K, Ando Y, Kibe S, Nakayama H, Takesue S, Endo S, Abe T, Okumura T, Iwamoto C, Shindo K, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M
- Organizer
  Pancreas 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10598
[Presentation] Endo180 Expression and Histologic Categorization in Cancer Stroma is an Independent Prognostic Index in Pancreatic Cancer.2018
- Author(s)
  Koikawa K, Ohuchida K, Yonenaga A, Sagara A, Ando Y, Kibe S, Takesue S,Nakayama H, Iwamoto C, Shindo K, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  49th Annual Meeting of the APA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10598
[Presentation] ADM are Classified Three Distinct Phenotypical Profiles Depending on its Different Microenvironment2018
- Author(s)
  S. Kibe, K. Ohuchida, Y. Ando, S. Takesue, M. Nakayama, T. Abe, S. Endo, K. Koikawa, T. Okumura, C. Iwamoto, K. Shindo, T. Moriyama, K. Nakata, S. Nagai, Y. Miyasaka, M. Shimamoto, T. Ohtsuka, K. Mizumoto, M. Nakamura.
- Organizer
  American Pancreatic Association Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07943
[Presentation] 膵癌局所浸潤を先導するleading cell －膵星細胞がつくる膵癌局所微少環境の機序解明－2017
- Author(s)
  肥川和寛、大内田研宙、安藤陽平、岐部晋、中山宏道、武居晋、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第38回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-15K09046
[Presentation] 膵癌局所浸潤を先導するleading cell －膵星細胞がつくる膵癌局所微少環境の機序解明－2017
- Author(s)
  肥川和寛、大内田研宙、安藤陽平、岐部晋、中山宏道、武居晋、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第38回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] Pancreatic organoids elucidate the new mechanisms of pancreatic cancer local invasion.2017
- Author(s)
  Koikawa K, Ohuchida K, Ando Y, Kibe S, Nakayama H, Takesue S, Yan Z, Abe T, Okumura T, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Okabe Y, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 48th Annual Meeting of The American Pancreatic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10598
[Presentation] 膵癌における膵周囲脂肪組織線維化と脂肪組織由来幹細胞の役割2017
- Author(s)
  奥村隆志、大内田研宙、安藤陽平、岐部晋、武居晋、中山宏道、阿部俊也、遠藤翔、肥川和寛、厳子龍、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K10187
[Presentation] 膵癌局所浸潤を先導するleading cell －膵星細胞がつくる膵癌局所微少環境の機序解明－2017
- Author(s)
  肥川和寛、大内田研宙、安藤陽平、岐部晋、中山宏道、武居晋、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第38回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-15H04933
[Presentation] 脂肪組織由来幹細胞は膵癌における癌関連線維芽細胞の供給源となり腫瘍形成を促進する2017
- Author(s)
  肥川和寛、奥村隆志、大内田研宙、岐部晋、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第48回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-15K10187
[Presentation] Pancreatic organoids elucidate the new mechanisms of pancreatic cancer local invasion2017
- Author(s)
  Koikawa K, Ohuchida K, Ando Y, Kibe S, Nakayama H, Takesue S, Yan Z, Abe T, Okumura T, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Okabe Y, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 48th Annual Meeting of The American Pancreatic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] 膵星細胞におけるEndo180発現の意義および治療標的因子としての検討2017
- Author(s)
  肥川和寛、大内田研宙、安藤陽平、岐部晋、中山宏道、武居晋、阿部俊也、遠藤翔、奥村隆志、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第48回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-15K09046
[Presentation] Pancreatic organoids elucidate the new mechanisms of pancreatic cancer local invasion2017
- Author(s)
  Koikawa K, Ohuchida K, Ando Y, Kibe S, Nakayama H, Takesue S, Yan Z, Abe T, Okumura T, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Okabe Y, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 48th Annual Meeting of The American Pancreatic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10188
[Presentation] Adipose Tissue Derived Stromal Cells Accelerate Tumor Progression and Desmoplasia of Pancreatic Cancer2017
- Author(s)
  Okumura T, Ohuchida K, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 48th Annual Meeting of The American Pancreatic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10598
[Presentation] 膵星細胞が誘導する新たな膵癌局所微小浸潤機序の解明2017
- Author(s)
  肥川和寛、大内田研宙、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第25回日本消化器関連学会週間　第15回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-15H04933
[Presentation] 膵星細胞におけるEndo180発現の意義および治療標的因子としての検討2017
- Author(s)
  肥川和寛、大内田研宙、安藤陽平、岐部晋、中山宏道、武居晋、阿部俊也、遠藤翔、奥村隆志、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第48回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] 膵星細胞におけるEndo180発現の意義および治療標的因子としての検討2017
- Author(s)
  肥川和寛、大内田研宙、安藤陽平、岐部晋、中山宏道、武居晋、阿部俊也、遠藤翔、奥村隆志、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第48回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-15H04933
[Presentation] 膵星細胞が誘導する新たな膵癌局所微小浸潤機序の解明2017
- Author(s)
  肥川和寛、大内田研宙、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第25回日本消化器関連学会週間　第15回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] 膵オルガノイドによる新たな膵癌局所微小浸潤機序の解明‐膵星細胞が誘導する基底膜破壊と間質浸潤‐2017
- Author(s)
  肥川和寛、大内田研宙、岐部晋、安藤陽平、武居晋、中山宏道、阿部俊也、遠藤翔、奥村隆志、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] オートファジーは膵星細胞の活性化に関与しており、その抑制は膵癌の進展を制御する2017
- Author(s)
  仲田興平、遠藤翔、大内田研宙、水元一博、小田義直、橋爪誠、中村雅史
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10188
[Presentation] 癌関連腹膜中皮細胞は膵癌腹膜播腫形成を促進する2017
- Author(s)
  阿部俊也、大内田研宙、肥川和寛、遠藤翔、奥村隆志、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10598
[Presentation] 膵星細胞が誘導する新たな膵癌局所微小浸潤機序の解明2017
- Author(s)
  肥川和寛、大内田研宙、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第25回日本消化器関連学会週間　第15回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-15K09046
[Presentation] 脂肪組織由来幹細胞は膵癌における癌関連線維芽細胞の供給源となり腫瘍形成を促進する2017
- Author(s)
  肥川和寛、奥村隆志、大内田研宙、岐部晋、森山大樹、仲田興平、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第48回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-15K10188
[Presentation] マウスモデルを用いた膵癌微小転移形成機序の解析2017
- Author(s)
  武居晋、大内田研宙、安藤陽平、岐部晋、中山宏道、阿部俊也、肥川和寛、遠藤翔、厳子龍、奥村隆志、仲田興平、森山大樹、宮坂義浩、真鍋達也、大塚隆生、永井英司、水元一博、中村雅史
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10598
[Presentation] 膵星細胞は基質リモデリングにより、leading cell として膵癌浸潤を先導する2016
- Author(s)
  肥川和寛、大内田研宙、佐田政史、阿部俊也、遠藤翔、奥村隆志、堀岡宏平、森山大樹、宮坂義浩、真鍋達也、大塚隆生、大内田理一、植木隆、永井英司、水元一博、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] Peripancreatic adipose tissue inhibits the proliferation of pancreatic cancer cells and contributes chemoresistance.2016
- Author(s)
  Okumura T, Ohuchida K, Abe T, Endo S, Koikawa K, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Nakamura M
- Organizer
  Joint Meeting of the IAP / JPS / AOPA 2016
- Place of Presentation
  Sendai(JAPAN)
- Year and Date
  2016-08-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10187
[Presentation] 膵癌におけるCD51発現は予後と相関する2016
- Author(s)
  堀岡宏平、大内田研宙、佐田政史、鄭彪、千々岩芳朗、吉田真樹、奥村隆志、遠藤翔、阿部俊也、肥川和寛、大塚隆生、植木隆、永井英司、水元一博、小田義直、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15H04933
[Presentation] 膵癌の癌関連線維芽細胞におけるオートファジーの役割2016
- Author(s)
  遠藤翔、仲田興平、佐田政史、大内田研宙、阿部俊也、肥川和寛、奥村隆志、佐田政史、堀岡宏平、水内祐介、大塚隆生、植木隆、永井英司、水元一博、小田義直、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15K10188
[Presentation] Novel role of peritoneal mesothelial cells that lead to pancreatic cancer peritoneal dissemination formation.2016
- Author(s)
  Abe T, Ohuchida K, Kibe S, Ando Y, Nakayama H, Takesue S, Endo S, Koikawa K, Okumura T, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Nakamura M.
- Organizer
  47th Annual Meeting of the American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] 膵周囲脂肪組織は肝癌細胞の遊走・浸潤機能を増強し、局所浸潤に関与する2016
- Author(s)
  奥村隆志、大内田研宙、武居晋、中山宏道、阿部俊也、遠藤翔、肥川和寛、千々岩芳朗、吉田真樹、鄭彪、佐田政史、堀岡宏平、森山大樹、三好圭、宮坂義浩、真鍋達也、大塚隆生、植木隆、永井英司、水元一博、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K10187
[Presentation] Autophagy Drives Pancreatic Stellate Cells Activation and Promotes Pancreatic Cancer2016
- Author(s)
  Endo S, Nakata K, Ohuchida K, Ando Y, Kibe S, Takesue S, Nakayama H, Abe T, Koikawa K, Okumura T, Mizuuchi Y, Moriyama T, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Oda Y, Nakamura M
- Organizer
  47th Annual Meeting of the American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10188
[Presentation] 膵癌腹膜播種形成を導く腹膜中皮細胞の新たな役割～防御から促進へ～2016
- Author(s)
  阿部俊也、大内田研宙、遠藤翔、肥川和寛、千々岩芳朗、吉田真樹、奥村隆志、堀岡宏平、佐田政史、大塚隆生、植木隆、永井英司、水元一博、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] 低酸素下膵星細胞による癌間質マトリックス・リモデリングは膵癌浸潤能を増強する2016
- Author(s)
  佐田政史、大内田研宙、阿部俊也、遠藤翔、肥川和寛、奥村隆志、千々岩芳朗、吉田真樹、堀岡宏平、森山大樹、宮坂義浩、大塚隆生、植木隆, 永井英司、水元一博、小田義直、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15K09046
[Presentation] Fatty acid uptake via CD36 enhances invasiveness of pancreatic cancer cells.2016
- Author(s)
  Okumura T, Ohuchida K, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Nakamura M
- Organizer
  The 47th Annual meeting of American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10187
[Presentation] 癌と間質を同時に標的とするカルパイン阻害薬カルペプチンの膵癌に対する治療効果の検討2016
- Author(s)
  吉田真樹、宮坂義浩、大内田研宙、遠藤翔、阿部俊也、肥川和寛、厳子龍、千々岩芳朗、奥村隆志、佐田政史、堀岡宏平、鄭彪、森山大樹、真鍋達也、大塚隆生、植木隆、永井英司、水元一博、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15H04933
[Presentation] 膵星細胞は基質リモデリングにより、leading cell として膵癌浸潤を先導する2016
- Author(s)
  肥川和寛、大内田研宙、佐田政史、阿部俊也、遠藤翔、奥村隆志、堀岡宏平、森山大樹、宮坂義浩、真鍋達也、大塚隆生、大内田理一、植木隆、永井英司、水元一博、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K09046
[Presentation] Endo180 regulate phosphorylation of myosin light chain 2 activity and increase the ability of extracellular matrix remodeling in leading pancreatic stellate cells.2016
- Author(s)
  koikawa K, Ohuchida K, Kibe S, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Okumura T, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Nakamura M.
- Organizer
  The 47th Annual meeting of American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09046
[Presentation] Endo180 regulate phosphorylation of myosin light chain 2 activity and increase the ability of extracellular matrix remodeling in leading pancreatic stellate cells.2016
- Author(s)
  Koikawa K, Ohuchida K, Kibe S, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Okumura T, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Nakamura M
- Organizer
  47th Annual Meeting of the American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] Suppression of CD51 in Pancreatic Stellate Cells Inhibits Tumor Growth by Reducing Stroma and Altering Tumor-Stromal Interaction in Pancreatic Cancer2015
- Author(s)
  Horioka K, Ohuchida K, Sada M, Zheng B, Ohtsuka T, Ueki T, Nagai E, Mizumoto K, Oda Y, Nakamura M
- Organizer
  American Pancreatic Association 46th Annual Meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] 脂肪組織由来幹細胞は膵癌細胞の遊走・浸潤を促進し悪性度に関与する2015
- Author(s)
  奥村隆志、大内田研宙、阿部俊也、遠藤翔、肥川和寛、千々岩芳朗、吉田真樹、佐田政史、堀岡宏平、真鍋達也、大塚隆生、高畑俊一、植木隆、永井英司、水元一博、中村雅史、田中雅夫
- Organizer
  JDDW2015 第23回消化器関連学会週間
- Place of Presentation
  東京都
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10187
[Presentation] Pancreatic Stellate Cells Lead and Promote the Local Invasion of Cancer Cells, by Physically Remodeling the Extracellular Matrix with Collagen Fiber Alignment in Pancreatic Cancer2015
- Author(s)
  Koikawa K, Ohuchida K, Sada M, Abe T, Endo S, Horioka K, Moriyama T, Miyasaka Y, Ohtsuka T, Ohuchida R, Ueki T, Nagai E, Mizumoto K, Nakamura M
- Organizer
  American Pancreatic Association 46th Annual Meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04933
[Presentation] Suppression of CD51 in Pancreatic Stellate Cells Inhibits Tumor Growth by Reducing Stroma and Altering Tumor-Stromal Interaction in Pancreatic Cancer2015
- Author(s)
  Horioka K, Ohuchida K, Sada M, Zheng B, Ohtsuka T, Ueki T, Nagai E, Mizumoto K, Oda Y, Nakamura M
- Organizer
  American Pancreatic Association 46th Annual Meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461024
[Presentation] Suppression of CD51 in Pancreatic Stellate Cells Inhibits Tumor Growth by Reducing Stroma and Altering Tumor-Stromal Interaction in Pancreatic Cancer2015
- Author(s)
  Horioka K, Ohuchida K, Sada M, Zheng B, Ohtsuka T, Ueki T, Nagai E, Mizumoto K, Oda Y, Nakamura M
- Organizer
  American Pancreatic Association 46th Annual Meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462118
[Presentation] Pancreatic Stellate Cells Lead and Promote the Local Invasion of Cancer Cells, by Physically Remodeling the Extracellular Matrix with Collagen Fiber Alignment in Pancreatic Cancer2015
- Author(s)
  Koikawa K, Ohuchida K, Sada M, Abe T, Endo S, Horioka K, Moriyama T, Miyasaka Y, Ohtsuka T, Ohuchida R, Ueki T, Nagai E, Mizumoto K, Nakamura M
- Organizer
  American Pancreatic Association 46th Annual Meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10185
[Presentation] calpain阻害剤であるcalpainによる膵癌細胞及び膵星細胞への抑制効果の検討2015
- Author(s)
  吉田真樹、大内田研宙、千々岩芳朗、奥村隆志、田中友晴、佐田政史、堀岡宏平、藤原謙次、森山大樹、宮坂義浩、大塚隆生、高畑俊一、小田義直、水元一博、田中雅夫
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25462116
[Presentation] Suppression of CD51 in Pancreatic Stellate Cells Inhibits Tumor Growth by Reducing Stroma and Altering Tumor-Stromal Interaction in Pancreatic Cancer2015
- Author(s)
  Horioka K, Ohuchida K, Sada M, Zheng B, Ohtsuka T, Ueki T, Nagai E, Mizumoto K, Oda Y, Nakamura M
- Organizer
  American Pancreatic Association 46th Annual Meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04933
[Presentation] 膵癌関連繊維芽細胞におけるCD146発現と膵がんの進展抑制2014
- Author(s)
  鄭彪、大内田研宙、崔林、水内祐介、藤原謙次、赤川進、堀岡宏平、田中友晴、佐田政史、仲田興平、前山良、大塚隆生、小田義直、水元一博、田中雅夫
- Organizer
  第45回日本膵臓学会大会
- Place of Presentation
  北九州市
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-24390319
[Presentation] トラニラストによる膵星細胞の抑制についての検討2014
- Author(s)
  田中友晴、大内田研宙、水元一博、奥村隆志、千々岩芳朗、吉田真樹、佐田政史、堀岡宏平、鄭彪、赤川進、藤原謙次、仲田興平、宮坂義浩、前山良、大塚隆生、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-24390319
[Presentation] 膵癌におけるTM4SF1発現の意義2014
- Author(s)
  鄭彪、崔林、大内田研宙、進藤幸治、藤原謙次、赤川進、堀岡宏平、田中友晴、佐田政史、吉田真樹、千々岩芳朗、奥村隆志、仲田興平、大塚隆生、小田義直、水元一博、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-25461024
[Presentation] 膵癌間質の線維配列が癌細胞の形態と浸潤方向に与える影響2014
- Author(s)
  佐田政史、大内田研宙、堀岡宏平、田中友晴、鄭彪、Cases AI、赤川進、藤原謙次、仲田興平、宮坂義浩、前山良、大塚隆生、高畑俊一、水元一博、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-24390319
[Presentation] 膵癌関連繊維芽細胞におけるCD146発現と膵がんの進展抑制2014
- Author(s)
  鄭彪、大内田研宙、崔林、水内祐介、藤原謙次、赤川進、堀岡宏平、田中友晴、佐田政史、仲田興平、前山良、大塚隆生、小田義直、水元一博、田中雅夫
- Organizer
  第45回日本膵臓学会大会
- Place of Presentation
  北九州市
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-25670585
[Presentation] 膵癌細胞からの作用により膵星細胞中のNPAS1が増加する2014
- Author(s)
  藤原謙次、大内田研宙、赤川進、大塚隆夫、高畑俊一、水元一博、田中雅夫
- Organizer
  第45回日本膵臓学会大会
- Place of Presentation
  北九州市
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-25670585
[Presentation] 膵癌関連繊維芽細胞におけるCD146発現と膵がんの進展抑制2014
- Author(s)
  鄭彪、大内田研宙、崔林、水内祐介、藤原謙次、赤川進、堀岡宏平、田中友晴、佐田政史、仲田興平、前山良、大塚隆生、小田義直、水元一博、田中雅夫
- Organizer
  第45回日本膵臓学会大会
- Place of Presentation
  北九州市
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-24591014
[Presentation] 膵癌間質の線維配列が癌細胞の形態と浸潤方向に与える影響2014
- Author(s)
  佐田政史、大内田研宙、堀岡宏平、田中友晴、鄭彪、Cases AI、赤川進、藤原謙次、仲田興平、宮坂義浩、前山良、大塚隆生、高畑俊一、水元一博、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-25461024
[Presentation] Tissue Tablet(組織タブレット)法-手術切除組織の保存・管理のための新しいアプローチ-2012
- Author(s)
  寅田信博、大内田研宙、崔林、水元一博、相島慎一、小田義直、田中雅夫
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉市
- Year and Date
  2012-04-12
- Data Source
  KAKENHI-PROJECT-23659654
[Presentation] Tissue Tablet 法-新鮮凍結サンプルの新しい保存・管理法-2012
- Author(s)
  寅田信博、大内田研宙、崔林、水元一博、相島慎一、小田義直、田中雅夫
- Organizer
  第49回九州外科
- Place of Presentation
  佐賀市
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-23659654
[Presentation] 膵癌におけるCD271陽性膵星細胞の意義2012
- Author(s)
  藤原謙次, 大内田研宙, 進藤幸治, 赤川進, 江口大樹, 小薗真吾, 池永直樹, 崔林, 相島慎一, 大塚隆生, 高畑俊一, 水元一博, 小田義直, 田中雅夫
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-22591523
[Presentation] CD271+ pancreatic stellate cells are correlated with prognosis of patients with pancreatic cancer and regulated by interaction2012
- Author(s)
  Kenji Fujiwara, Kenoki Ohuchida, Koji Shindo, Shingo Kozono, Naoki Ikenaga, LinCui, Shinichi Aishima, Masafumi Nakamura, Kazuhiro Mizumoto, Yoshinao Oda, Masao Tanaka
- Organizer
  cancer cells International Symposium on Pancreas Cancer 2012 in Kyoto
- Place of Presentation
  京都
- Year and Date
  2012-10-06
- Data Source
  KAKENHI-PROJECT-22591523
[Presentation] CD10陽性膵星細胞は膵癌の進展を促進する2011
- Author(s)
  池永直樹, 大内田研宙, 水元一博, 崔林, 小薗真吾, 藤田逸人, 大塚隆生, 田中雅夫
- Organizer
  第111回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22591523
[Presentation] CD10 positive pancreatic stellatecells enhance the progression of pancreatic cancer2011
- Author(s)
  Naoki Ikenaga, Kenoki Ohuchida, Kazuhiro Mizumoto, Kenji Fujiwara, Shingo Kozono , Takao Otsuka, Masafumi Nakamura, Masao Tanaka
- Organizer
  42nd Annual Meeting of the American Pancreatic Association
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22591523
[Presentation] MicroRNA-373 is downregulated in pancreatic cancer and repressed its invasiveness via induction of mesenchymal-episerial transition2010
- Author(s)
  Nakata K, Ohuchida K, Mizumoto K, Nagai E and Tanaka M
- Organizer
  Joint meeting of the international association of pancreatology and Japan pancreatic society
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-22390258
[Presentation] MicroRNA-10b is a useful prognostic marker in pancreatic cancer and promotes its invasiveness2010
- Author(s)
  Nakata K, Ohuchida K, Mizumoto K, Nagai E and Tanaka M
- Organizer
  Joint meeting of the international association of pancreatology and Japan pancreatic society
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-22390258
[Presentation] 膵癌におけるマイクロRNA-17-5pの発現解析と発現増強による増殖・浸潤促進効果2008
- Author(s)
  余俊, 森山大樹, 大内田研宙, 崔林, 佐藤典宏, 当間宏樹, 高畑俊一, 永井英司, 水元一博, 田中雅夫
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-19591592
[Presentation] MicroRNA-10α is Overexpressed in Human Pancreatic Cancer and Involved in its2008
- Author(s)
  Kenoki Ohuchida, Kazuhiro Mizumoto, TaikiMoriyama, Shunichi Takahata, Hiroki Toma,Norihiro Sato, Eishi Nagai, and Masao Tanaka
- Organizer
  Invasiveness possibly via Suppression of the HOXA1 gene Amecican Pancreatic Assosiation
- Data Source
  KAKENHI-PROJECT-19591592
[Presentation] Micro RNA(miR-17-5p)is overexpressed in pancreaticcancer, and upregulation of miR-17-5p enhancedcancer cell proliferation and invasion in vitro2008
- Author(s)
  Jun Yu, Taiki Moriyama, Kenoki Ohuchida,Lin Cui, Norihiro Sato, Masafumi Nakamura,Shunichi Takahata, Eishi Nagai, KazuhiroMizumoto, Masao Tanaka
- Organizer
  Digestive Disease Week
- Data Source
  KAKENHI-PROJECT-19591592
[Presentation] 膵癌におけるマイクロRNA-17-5pの発現解析と発現増強による増殖・浸潤促進効果2008
- Author(s)
  余俊、森山大樹、大内田研宙、崔林、佐藤典宏、当間宏樹、高畑俊一、永井英司、水元一博、田中雅夫
- Organizer
  第108回日本外科学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19591592
[Presentation] ヒト膵癌細胞株におけるマイクロRNAの過剰発現2007
- Author(s)
  森山大樹、大内田研宙、水元一博、余俊、佐藤典宏、当間宏樹、永井英司、田中雅夫
- Organizer
  第107回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591592
[Presentation] ヒト膵癌細胞におけるマイクロRNA・miR-21の発現解析と増殖・浸潤促進作用2007
- Author(s)
  森山大樹、大内田研宙、水元一博、余俊、佐藤典宏、当間宏樹、永井英司、田中雅夫
- Organizer
  第38回日本膵臓学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19591592
[Presentation] 膵癌の個別化治療を目指したパラフィン包理組織のRNA定量解析〜膵癌術後短期死亡群におけるS100A4の過剰発現2007
- Author(s)
  水元一博, 他
- Organizer
  第107回日本外科学会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209040
[Presentation] Implication of S100P in pancreatic cancer as an early developmental marker and a therapeutic target2006
- Author(s)
  Ohuchida, k., Mizumoto, k., Konomi, H., Nagai, E., Yamaguchi, K., Tanaka, M.
- Organizer
  DDW
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209040
[Presentation] Quantitative Analysis of hTERT mRNA in Pancreatic Juice Is More Useful for Differentiating Pancreatic Cancer from IPMN than from Chronic Pancreatitis2006
- Author(s)
  Ohuchida, k., Mizumoto, k., Konomi, H., Nagai, E., Yamaguchi, K., Tanaka M
- Organizer
  DDW
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209040
[Presentation] Significance of Phosphorylation of Chk2 in Intraductal Papillary Mucinous Neoplasms of the Pancreas2006
- Author(s)
  Miyasaka, Y., Nagai, E., Yamaguchi, H., Fujii, K., Inoue, T., Ohuchida, K., Mizumoto, K., Tsuneyoshi, M., Tanaka M
- Organizer
  American Pancreatic Association &amp ; International Association of Pancreatology
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209040
[Presentation] Twist a novel oncogene, is up-regulated in pancreatic cancer ; clinical implication of Twist expression in pancreatic juice2006
- Author(s)
  Ohuchida, k., Mizumoto, k., Konomi, H., Nagai, E., Yamaguchi, K., Tanaka M
- Organizer
  DDW
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209040
[Presentation] Implication of S100P in pancreatic cancer as an early developmental marker and a therapeutic target2006
- Author(s)
  Ohuchida, k., Mizumoto, k., Konomi, H., Nagai, E., Yamaguchi, K., Tanaka M
- Organizer
  DDW
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209040
[Presentation] LIM only 4 is overexpressed with the progress of invasive ductal carcinoma and intraductal papillary mucinous neoplasm2006
- Author(s)
  Yu, J., Ohuchida, K., Mizumoto, K., Nagai, E., Tanaka, M
- Organizer
  American Pancreatic Association &amp ; International Association of Pancreatology
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209040
[Presentation] The role of S100 family as diagnostic marker and therapeutic target in pancreatic cancer2005
- Author(s)
  Mizumoto, K., Ohuchida, K., Konomi, H., Nagai, E., Yamaguchi, K., Tanaka M
- Organizer
  15th World Congress of the International Association of Surgeons and Gastroenterologists
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209040

1. OHUCHIDA Kenoki (20452708)

# of Collaborated Projects: 23 results

# of Collaborated Products: 116 results
2. TANAKA Masao (30163570)

# of Collaborated Projects: 18 results

# of Collaborated Products: 30 results
3. EISHI Nagai (30264021)

# of Collaborated Projects: 11 results

# of Collaborated Products: 28 results
4. TOMA Hiroki (80437780)

# of Collaborated Projects: 8 results

# of Collaborated Products: 3 results
5. TOMINAGA Yohei (90304823)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. SAKAI Hiroshi (80611665)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. SHUNICHI Takahata (50437779)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
8. UEDA Junji (90529801)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
9. 小川向洋 (90294933)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
10. ONIMARU Manabu (80529876)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
11. EGAMI Takuya (40507787)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
12. MIYASAKA Yoshihiro (40507795)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
13. SHIMURA Hideo (80178996)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
14. ONA Toshihiro (10346835)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. INOUE Shigetaka (00529802)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. OHTSUKA Takao (20372766)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
17. SHIMIZU Yukiko (10404021)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
18. SHIMAMOTO Masaya (00457433)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
19. MORISAKI Takashi (90291517)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
20. NAKAMURA Toshikazu (00049397)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
21. MORIYAMA Taiki (70586859)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
22. 藤田逸人 (40611281)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
23. SATO Norihro (20423527)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
24. TKENAKA Shigeori (60188208)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
25. NAKAMURA Kenjiro (30207873)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
26. SHIRAHANE Kengo (10529803)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
27. MANABE Tatsuya (60546464)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
28. NABAE Toshinaga (10467889)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
29. NAKATA Kohei (30419569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
30. MATSUDA Takehisa (60142189)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
31. MATSUMOTO Kunio (90201780)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
32. 岩本千佳 (10752842)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
33. 久保真 (60403961)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
34. 進藤幸治 (00788432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
35. 水内祐介 (20849088)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
36. TSUTSUMI Kohsuke (00467937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. MAEYAMA Ryo (10611668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. SATOH Hiroshi (40196267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. UCHIYAMA Akihiko (20294936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. IDE Toshinori (60012746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 仏坂正幸 (10294935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 柳雄介 (40182365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 田邊麗子 (70423548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 山本健 (60274528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 許斐裕之 (30343320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 甲斐昌也 (10755242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 中村雅史 (30372741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
48. 大西秀哉 (30553276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 寅田信博 (00398075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
50. 小薗真吾 (40706850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 木庭遼 (10866776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 中山宏道 (80866773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 池永直樹 (90759755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 三好圭 (70755272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. KINOSHITA Moritoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. 有馬剛

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. OKUMURA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. ENDO Sho

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
59. KOIKAWA Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. TAKESUE Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. MIURA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 佐田政史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. 橋爪誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
64. 森健策

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
65. 小田義直

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
66. 藤田廣志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
67. 清水昭伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
68. 藤村由紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 中山功一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
70. 森泰寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIZUMOTO Kazuhiro 水元 一博

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ヒト膵癌組織を使用した抗癌剤スクリーニングシステムの構築とその治療応用Ongoing

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PDX-3D法を用いた創薬ライブラリ構築と新規膵癌治療薬探索Principal InvestigatorOngoing

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大腸癌肝転移オルガノイドと単細胞解析を用いた微小環境改変に伴う治療抵抗機序の解明Ongoing

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単一細胞解析とオルガノイドを用いた微小環境依存性に基づく膵癌subtype分類Ongoing

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膵癌微小環境によるAcinar atrophyの新機序と局所浸潤での役割の解明Ongoing

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個別化精密がん免疫療法開発を目的とした腫瘍組織からのネオアンチゲン解析Ongoing

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3D膵癌オルガノイドモデルを用いた新たな癌細胞死形態とそれに伴う浸潤機構の解明Ongoing

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Induction of tumor-suppressing pancreatic stellate cell subpopulation by pancreatic cancer microenvironment reprogrammingPrincipal Investigator

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MIZUMOTO Kazuhiro 水元一博