Nakata Kohei 仲田興平

… Alternative Names

Researcher Number	30419569
Affiliation (Current)	2021: 九州大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2021: 九州大学, 大学病院, 講師 2016 – 2019: 九州大学, 大学病院, 助教 2015: 九州大学, 大学病院, 特別教員 2014: 九州大学, 医学(系)研究科(研究院), 共同研究員 2014: 九州大学, 医学研究院, 共同研究員 2012 – 2013: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator オートファジー / 膵臓癌 / 膵星細胞 / 膵癌 / 癌間質相互作用 / 癌 / 癌幹細胞 / 細胞周期 / Drug Delivary System / 人工ウイルス … More Except Principal Investigator 膵癌 / オートファジー / 癌微小環境 / 膵星細胞 / 膵臓癌 / 癌関連線維芽細胞 / PDX / シングルセル解析 / heterogeneity / 治療抵抗性 / 細胞外マトリックス / 低酸素 / PLOD2 / 線維構築 / 治療耐性 / ウイルス / レンチウイルス / calpeptin / ramininα4 / MAL2遺伝子 / Nodal / HDAC1 / Sainomycin / Pirfenidone / S100A4 / ポックスウイルス / 細胞外基質クリアランス / 上皮間葉移行 / Pancreatic cancer / microRNA / miR-5100 / podcalyxin (PODXL) / CD110 / 人工ウイルス / Mir-5100 / podcalyxin / オルガノイド / MiR-5100 / podocalyxin / NGS解析 / 遺伝子変異 / 微小環境 / ゲノム不均一性 / 次世代シークエンサー / リキッドバイオプシー / 次世代シーケンサー / 遺伝子変異解析 / KPCマウス / 不均一性 (heterogeneity) / 患者腫瘍組織移植モデル (PDXモデル) / 腫瘍内不均一性 / 患者腫瘍組織移植モデル / 不均一性(heterogeneity) / PDXマウス / 化合物スクリーニング / ナノ粒子 / 間質 / 薬剤送達 / 薬物送達システム Less

PDX-3D法を用いた創薬ライブラリ構築と新規膵癌治療薬探索
- Principal Investigator
  
  水元一博
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  International University of Health and Welfare
  Kyushu University
膵星細胞抑制薬とナノ粒子の組み合わせにより間質障壁を打破する新規膵癌治療薬の開発
- Principal Investigator
  
  江上拓哉
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
膵癌PDXライブラリ-を用いたシングルセル解析による腫瘍内治療抵抗不均一性の解明
- Principal Investigator
  
  中村雅史
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
膵星細胞活性化におけるオートファジーを標的としたHIT化合物の同定とその評価Principal Investigator
- Principal Investigator
  
  仲田興平
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
NGS解析による膵癌微小環境とゲノム不均一性の解明とその治療への応用
- Principal Investigator
  
  進藤幸治
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
New drug discovery screening targeting autophagyPrincipal Investigator
- Principal Investigator
  
  NAKATA Kohei
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
A novel treatment of pancreatic cancer through microRNA management using a drug delivery system by artificial virus.
- Principal Investigator
  
  NAGAI Eishi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Elucidation of the role of microRNA as a cancer treatment-resistant mechanism by autophagyPrincipal Investigator
- Principal Investigator
  
  NAKATA Kohei
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Refractory cancer therapy development by cancer microenvironment elucidation and new drug delivery system based on autophagy
- Principal Investigator
  
  NAGAI Eishi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
The development of pancreatic cancer therapy based on regulating extracellular matrix remodeling by pancreatic stellate cells
- Principal Investigator
  
  MIYASAKA Yoshihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
The improvement of therapy-resistance with modified new virus and application to the treatment in pancreatic cancer
- Principal Investigator
  
  EGAMI Takuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of novel therapies that focus on autophagy-induced cancer cell substrate clearance function
- Principal Investigator
  
  NAGAI Eishi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Elucidation of G0 phase maintenance mechanism by autophagy in cancer stem cells and development of artificial virus therapy methodPrincipal Investigator
- Principal Investigator
  
  NAKATA Kohei
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
The role of autophagy in tumor-stromal cell interactionPrincipal Investigator
- Principal Investigator
  
  NAKATA Kohei
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] Necroptosis in Pancreatic Cancer Promotes Cancer Cell Migration and Invasion by Release of CXCL52020
- Author(s)
  Yohei Ando, Kenoki Ohuchida , Yoshiki Otsubo, Shin Kibe, Shin Takesue, Toshiya Abe, Chika Iwamoto, Koji Shindo, Taiki Moriyama, Kohei Nakata, Yoshihiro Miyasaka, Takao Ohtsuka, Yoshinao Oda, Masafumi Nakamura
- Journal Title
  
  PLOS ONE
  
  Volume: 15
- DOI
  10.1371/journal.pone.0228015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07943, KAKENHI-PROJECT-18K08708, KAKENHI-PROJECT-19K09125, KAKENHI-PROJECT-18H02881, KAKENHI-PROJECT-19K21274, KAKENHI-PROJECT-18K16366
[Journal Article] FoundationOne CDx gene profiling in Japanese pancreatic ductal adenocarcinoma patients: a single-institution experience2020
- Author(s)
  Kimura R, Ohtsuka T, Kubo M, Kajihara A, Fujii A, Watanabe Y, Mori Y, Ikenaga N, Nakata K, Shindo K, Ohuchida K,Nakamura M
- Journal Title
  
  Surgery Today
  
  Volume: 51 Pages: 619-626
- DOI
  10.1007/s00595-020-02123-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02881, KAKENHI-PROJECT-18K08577
[Journal Article] Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer-stromal interaction and metastasis2019
- Author(s)
  Yan Zilong、Ohuchida Kenoki、Fei Shuang、Zheng Biao、Guan Weiyu、Feng Haimin、Kibe Shin、Ando Yohei、Koikawa Kazuhiro、Abe Toshiya、Iwamoto Chika、Shindo Koji、Moriyama Taiki、Nakata Kohei、Miyasaka Yoshihiro、Ohtsuka Takao、Mizumoto Kazuhiro、Hashizume Makoto、Nakamura Masafumi
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 38 Pages: 221-221
- DOI
  10.1186/s13046-019-1226-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16366, KAKENHI-PROJECT-18H02881, KAKENHI-PROJECT-17K10700, KAKENHI-PROJECT-17K10701
[Journal Article] Adipose tissue-derived stromal cells are sources of cancer-associated fibroblasts and enhance tumor progression by dense collagen matrix2019
- Author(s)
  Okumura T, Ohuchida K, Kibe S, Iwamoto C, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Koikawa K, Sada M, Horioka K, Mochidome N, Arita M, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Oda Y, Hashizume M, Nakamura M
- Journal Title
  
  International Journal of Cancer
  
  Volume: 144 Pages: 1401-1403
- DOI
  10.1002/ijc.31775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10700, KAKENHI-PROJECT-18K07943, KAKENHI-PROJECT-18K16366, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-16H05418, KAKENHI-PROJECT-18H02880, KAKENHI-PROJECT-17H06942, KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-17K19602, KAKENHI-INTERNATIONAL-15K21716
[Journal Article] Clinical assessment of the GNAS mutation status in patients with intraductal papillary mucinous neoplasm of the pancreas.2019
- Author(s)
  htsuka T, Tomosugi T, Kimura R, Nakamura S, Miyasaka Y, Nakata K, Mori Y, Morita M, Torata N, Shindo K, Ohuchida K, Nakamura M
- Journal Title
  
  Surgery Today
  
  Volume: 印刷中 Pages: 887-893
- DOI
  10.1007/s00595-019-01797-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05417, KAKENHI-PROJECT-18H02881, KAKENHI-PROJECT-19K08409, KAKENHI-PROJECT-17K10699
[Journal Article] S100P regulates the collective invasion of pancreatic cancer cells into the lymphatic endothelial monolayer2019
- Author(s)
  Nakayama H, Ohuchida K, Yonenaga A, Sagara A, Ando Y, Kibe S, Takesue S, Abe T, Endo S, Koikawa K, Okumura T, Shido K, Miyoshi K, Nakata K, Moriyama T, Miyasaka Y, Inoue S, Ohtsuka T, Mizumoto K, Nakamura M
- Journal Title
  
  International Journal of Oncology
  
  Volume: 55 Pages: 211-222
- DOI
  10.3892/ijo.2019.4812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02881, KAKENHI-PROJECT-17K10700
[Journal Article] Autophagy inhibition enhances antiproliferative effect of salinomycin in pancreatic cancer cells.2017
- Author(s)
  Endo Sho、Nakata Kohei、Sagara Akiko、Koikawa Kazuhiro、Ando Yohei、Kibe Shin、Takesue Shin、Nakayama Hiromichi、Abe Toshiya、Okumura Takashi、Moriyama Taiki、Miyasaka Yoshihiro、Ohuchida Kenoki、Ohtsuka Takao、Mizumoto Kazuhiro、Nakamura Masafumi
- Journal Title
  
  Pancreatology
  
  Volume: 17 Pages: 990-996
- DOI
  10.1016/j.pan.2017.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-16K10598, KAKENHI-PROJECT-16K10601, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-15K10188, KAKENHI-PROJECT-15K10189, KAKENHI-PROJECT-16K15621
[Journal Article] Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice2017
- Author(s)
  Endo S, Nakata K, Ohuchida K, Takesue S, Nakayama H, Abe T, Koikawa K, Okumura T, Sada M, Horioka K, Zheng B, Mizuuchi Y, Iwamoto C, Murata M, Moriyama T, Miyasaka Y, Ohtsuka T, Mizumoto K, Oda Y, Hashizume M, Nakamura M.
- Journal Title
  
  Gastroenterology
  
  Volume: 印刷中 Pages: 1492-1506
- DOI
  10.1053/j.gastro.2017.01.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06480, KAKENHI-PROJECT-15H03007, KAKENHI-PROJECT-16H06258, KAKENHI-PROJECT-16J03962, KAKENHI-PROJECT-25713050, KAKENHI-PROJECT-15K19895, KAKENHI-PROJECT-15K10188, KAKENHI-PROJECT-15K10189, KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-15K12544, KAKENHI-PROJECT-16K15621, KAKENHI-PROJECT-16K19937, KAKENHI-INTERNATIONAL-15K21716, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010
[Journal Article] Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination.2017
- Author(s)
  Abe T, Ohuchida K, Koikawa K, Endo S, Okumura T, Sada M, Horioka K, Zheng B, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 50 Pages: 457-467
- DOI
  10.3892/ijo.2016.3829
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05418, KAKENHI-PROJECT-16J03962, KAKENHI-PROJECT-26462063, KAKENHI-PROJECT-15K15498, KAKENHI-PROJECT-15K10185, KAKENHI-PROJECT-16K10599, KAKENHI-PROJECT-16K10600, KAKENHI-PROJECT-16K10602
[Journal Article] Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells2017
- Author(s)
  Okumura T, Ohuchida K, Sada M, Abe T, Endo S, Koikawa K, Iwamoto C, Miura D, Mizuuchi Y, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Oda Y, Hashizume M, Nakamura M.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 18280-18295
- DOI
  10.18632/oncotarget.15430
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06480, KAKENHI-PROJECT-16J03962, KAKENHI-PROJECT-26462066, KAKENHI-PROJECT-15K15498, KAKENHI-PROJECT-16K10601, KAKENHI-PROJECT-16K19937, KAKENHI-PROJECT-16K10600, KAKENHI-INTERNATIONAL-15K21716, KAKENHI-PROJECT-26713020, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108010
[Journal Article] 膵癌におけるmiRNA発現と上皮間葉転換2015
- Author(s)
  仲田興平、大内田研宙、大塚隆生、中村雅史
- Journal Title
  
  胆と膵
  
  Volume: 36 Pages: 1117-1122
- Data Source
  KAKENHI-PROJECT-25713050
[Journal Article] 膵癌におけるmiRNA発現と上皮間葉転換2015
- Author(s)
  仲田興平、大内田研宙、大塚隆生、中村雅史
- Journal Title
  
  胆と膵
  
  Volume: 36 Pages: 1117-1122
- Data Source
  KAKENHI-PROJECT-26670607
[Journal Article] MicroRNA-373 is down regulated in pancreatic cancer and inhibits cancer cell incasion2014
- Author(s)
  Nakata K, Ohuchida K, Mizumoto K, Aishima S, Oda Y, Nagai E, Tanaka M
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 21
- DOI
  10.1245/s10434-014-3676-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390318, KAKENHI-PROJECT-24390319, KAKENHI-PROJECT-24591014, KAKENHI-PROJECT-24592031, KAKENHI-PROJECT-24592032, KAKENHI-PROJECT-24659615, KAKENHI-PROJECT-25293285, KAKENHI-PROJECT-25293287, KAKENHI-PROJECT-25461024, KAKENHI-PROJECT-25670585, KAKENHI-PROJECT-25670586, KAKENHI-PROJECT-25670587, KAKENHI-PROJECT-25713050, KAKENHI-PROJECT-26293305, KAKENHI-PROJECT-26462063, KAKENHI-PROJECT-26670607
[Journal Article] MicroRNA-373 is down regulated in pancreatic cancer and inhibits cancer cell incasion2014
- Author(s)
  Nakata K, Ohuchida K, Mizumoto K, Aishima S, Nagai E, Oda Y and Tanaka M
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24659615
[Journal Article] laparoscopic surgery for gastric intestinal stromal tumor is feasible irrespective of tumor size2014
- Author(s)
  Kasetsermwiriya W, Nagai E, Nakata K, et al
- Journal Title
  
  J laparoendosc Adv Surg Tech A
  
  Volume: 24(3) Pages: 123-9
- Data Source
  KAKENHI-PROJECT-24659615
[Journal Article] Insulin-like growth factor II messenger RNA-binding protein-3 is a valuable diagnostic and prognostic marker of intraductal papillary mucinous neoplasm2013
- Author(s)
  Morimatsu K, Aishima S, Yamamoto H, Hayashi A, Nakata K, Oda Y, Shindo K, Fujino M, Tanaka M, Oda Y
- Journal Title
  
  Hum Pathol
  
  Volume: 44(9) Pages: 1714-21
- Data Source
  KAKENHI-PROJECT-24659615
[Journal Article] Feasibility and safety of intracorporeal esophagojejunostomy after laparoscopic total gastrectomy : Inverted T-shaped anastomosis using linear staplers2013
- Author(s)
  Nagai E, Ohuchida K, Nakata K, Toma H, Tanaka M
- Journal Title
  
  Surgery
  
  Volume: 153(5) Pages: 732-8
- Data Source
  KAKENHI-PROJECT-24659615
[Patent] オートファジー阻害剤及び抗癌剤2020
- Inventor(s)
  仲田興平
- Industrial Property Rights Holder
  仲田興平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-178556
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] 膵癌に対するナノ粒子DDSの有用性の検討2021
- Author(s)
  松本奏吉、仲田興平、伊達聡美、関維雨、相良亜希子、池永直樹、大内田研宙、中村雅史
- Organizer
  第57回九州外科学会
- Data Source
  KAKENHI-PROJECT-20K07661
[Presentation] 抗ヒスタミン薬Azelastineは膵星細胞の活性化を抑制する2021
- Author(s)
  相良亜希子、仲田興平、鐘坪杉、池永直樹、大内田研宙、水元一博、中村雅史
- Organizer
  第57回九州外科学会
- Data Source
  KAKENHI-PROJECT-20K07661
[Presentation] 癌関連線維芽細胞が膵癌分化度に与える影響についての検討2021
- Author(s)
  新川智彦、大内田研宙、中村祥一、久野恭子、奥田翔、大坪慶志輝、進藤幸治、池永直樹、森山大樹、永井俊太郎、仲田興平、中村雅史
- Organizer
  第57回九州外科学会
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] 微小環境因子依存性に基づいた膵癌subtype分類および薬物治療抵抗性についての検討2020
- Author(s)
  新川智彦、大内田研宙、奥田翔、大坪慶志輝、岩本千佳、進藤幸治、仲田興平、大塚隆生、中村雅史
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] Efficient Targeted Therapy for Pancreatic Cancer Using Nanosystem and Focusing on the Suppression of Pancreatic Stellate Cell Activation2020
- Author(s)
  Matsumoto S, Nakata K, Ikenaga N, Date S, Guan W, Sagara A, Ohuchida K, Ohtsuka T, Nakamura M
- Organizer
  14th World Congress of International Hepeto-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03754
[Presentation] Subtype classification of pancreatic ductal adenocarcinoma based on microenvironmental niche factors dependency and chemotherapy resistance2020
- Author(s)
  Shinkawa T, Ohuchida K, Iwamoto C, Shindo K, Nakata K, Ohtsuka T, Nakamura M
- Organizer
  14th World Congress of International Hepeto-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] Efficient Targeted Therapy for Pancreatic Cancer Using Nanosystem and Focusing on the Suppression of Pancreatic Stellate Cell Activation2020
- Author(s)
  Matsumoto S, Nakata K, Ikenaga N, Date S, Guan W, Sagara A, Ohuchida K, Ohtsuka T, Nakamura M
- Organizer
  14th World Congress of International Hepeto-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] ナノ粒子DDSを用いた新規膵星細胞活性化抑制剤の開発2020
- Author(s)
  松本奏吉、仲田興平、関維雨、相良亜希子、池永直樹、大内田研宙、大塚隆生、中村雅史
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] Human macrophages-derived CAF-like cells lead the invasion of pancreatic cancer2020
- Author(s)
  Iwamoto C, Ohuchida K, Shinkawa T, Otsubo Y, Shindo K, Moriyama T, Nakata K, Ohtsuka T, Nakamura M
- Organizer
  14th World Congress of International Hepeto-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] 膵癌微小環境の制御に着目した新規膵癌治療薬剤の探索2020
- Author(s)
  相良亜希子、仲田興平、山下智大、関維雨、松本奏吉、伊達聡美、池永直樹、大内田研宙、大塚隆生、中村雅史
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K07661
[Presentation] ナノ粒子DDSを用いた新規膵星細胞活性化抑制剤の開発2020
- Author(s)
  松本奏吉、仲田興平、関維雨、相良亜希子、池永直樹、大内田研宙、大塚隆生、中村雅史
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K07661
[Presentation] 膵癌微小環境の制御に着目した新規膵癌治療薬剤の探索2020
- Author(s)
  相良亜希子、仲田興平、山下智大、関維雨、松本奏吉、伊達聡美、池永直樹、大内田研宙、大塚隆生、中村雅史
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] Efficient Targeted Therapy for Pancreatic Cancer Using Nanosystem and Focusing on the Suppression of Pancreatic Stellate Cell Activation2020
- Author(s)
  Matsumoto S, Nakata K, Ikenaga N, Date S, Guan W, Sagara A, Ohuchida K, Ohtsuka T, Nakamura M
- Organizer
  14th World Congress of International Hepeto-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07661
[Presentation] Repositioning of Duloxetine as a New Drug for Targeting Pancreatic Cancer Microenvironment2019
- Author(s)
  Sagara A, Nakata K, Yamashita T, Guan W, Matsumoto S, Date S, Ohtsubo Y, Shinkawa T, Kimura R, Fujii A, Ando Y, Iwamoto C, Watanabe Y, Shindo K, Ikenaga N, Moriyama T, Ohuchida K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 50th Annual Meeting of the American Pancreatic Association(APA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] 膵癌におけるERK1/2阻害剤による癌間質相互作用の抑制効果の検討2019
- Author(s)
  新川智彦、厳子龍、大内田研宙、大坪慶志輝、松本奏吉、米永晃子、相良亜希子、関維雨、馮海旻、安藤陽平、岐部晋、武居晋、中山宏道、進藤幸治、森山大樹、仲田興平、宮坂義浩、永井俊太郎、大塚隆生、中村雅史
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] 膵癌細胞への異なった細胞死誘導による遊走・浸潤能への影響の比較2019
- Author(s)
  安藤陽平、大内田研宙、岐部晋、武居晋、中山宏道、森山大樹、仲田興平、宮坂義浩、大塚隆生、中村雅史
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] A new investigation of drug repurposing using for duloxetine as targeting pancreatic cancer microenvironment2019
- Author(s)
  Sagara A, Nakata　K, Yamashita T, Matsumoto S, Ohotsubo Y, Shinkawa T, Shindo K, Moriyama T, Ohuchida K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  Digestive Disease Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] AUTOPHAGY INHIBITION ENHANCES ANTIPROLIFERATIVE EFFECT OF SALINOMYCIN IN PANCREATIC CANCER CELLS2019
- Author(s)
  Sagara A, Nakata K, Endo S, Matsumoto S, Ohtsubo Y, Shinkawa Tomohiko S, Shindo K, Moriyama T, Ohuchida K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  Digestive Disease Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] Necroptosis in Pancreatic Cancer Promotes Cancer Cell Migration and Invasion by Release of CXCL52019
- Author(s)
  Ando Y, Ohuchida K, Otsubo Y, Sagara A, Kibe S, Takesue S, Nakayama M, Shindo K, Moriyama T, Nakata K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 50th Annual Meeting of the American Pancreatic Association(APA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] 膵癌細胞のオートファジー抑制は、サリノマイシンによる増殖抑制効果を増強する2019
- Author(s)
  相良亜希子、仲田興平、遠藤翔、大坪慶志輝、新川智彦、松本奏吉、米永晃子、安藤陽平、岐部晋、中山宏道、武居晋、進藤幸治、森山大樹、大内田研宙、大塚隆生、水元一博、中村雅史
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] 膵癌微小環境を構築する骨髄由来細胞が膵癌浸潤を先導する2019
- Author(s)
  岩本千佳、大内田研宙、安藤陽平、新川智彦、大坪慶志輝、進藤幸治、森山大樹、仲田興平、宮脇恒太、赤司浩一、江藤正俊、中村雅史
- Organizer
  第78回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] A Novel Target That Required for Autophagy, Associated With Activation of Pancreatic Stellate Cells, Promotes Pancreatic Cancer Progression2019
- Author(s)
  Guan W, Nakata K, Ohuchida K, Sagara A, Endo S, Ando Y, Yan Z, Matsumoto S, Shinkawa T, Ohtsubo Y, Iwamoto C, Moriyama T, Ikenaga N, Shindo K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 50th Annual Meeting of the American Pancreatic Association(APA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] BM-Derived Cells Destruct Basement Membrane and Induce Local Invasion of Pancreatic Cancer2019
- Author(s)
  Iwamoto C, Ohuchida K, Ando Y, Shinkawa T, Ohtsubo Y, Shindo K, Moriyama T, Nakata K, Miyawaki K, Ohtsuka T, Akashi K, Eto M, Nakamura M
- Organizer
  The 50th Annual Meeting of the American Pancreatic Association(APA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] S100Pが癌細胞塊のリンパ管内皮層へのクリアランスに関与しリンパ節転移に関わる2019
- Author(s)
  中山宏道、大内田研宙、相良亜希子、米永晃子、安藤陽平、岐部晋、武居晋、進藤幸治、仲田興平、森山大樹、宮坂義浩、藤田逸人、永井俊太郎、岡部安博、大塚隆生、水元一博、中村雅史
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H02881
[Presentation] Repositioning of Duloxetine as a New Drug for Targeting Pancreatic Cancer Microenvironment2019
- Author(s)
  Sagara A, Nakata K, Yamashita T, Guan W, Matsumoto S, Date S, Ohtsubo Y, Shinkawa T, Kimura R, Fujii A, Ando Y, Iwamoto C, Watanabe Y, Shindo K, Ikenaga N, Moriyama T, Ohuchida K, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 50th Annual Meeting of the American Pancreatic Association(APA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] 膵癌微小環境の制御に着目した既存薬剤を用いた膵癌治療の新たな展開2019
- Author(s)
  相良亜希子、仲田興平、山下智大、松本奏吉、大坪慶志輝、新川智彦、安藤陽平、大内田研宙、大塚隆生、中村雅史
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] オートファジー抑制は、サリノマイシンによる膵癌細胞増殖抑制効果を増強する2018
- Author(s)
  相良亜希子、仲田興平、遠藤翔、米永晃子、安藤陽平、岐部晋、中山宏道、武居晋、進藤幸治、森山大樹、宮坂義浩、大内田研宙、大塚隆生、水元一博、中村雅史
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] Endo180 Expression and Histologic Categorization in Cancer Stroma is an Independent Prognostic Index in Pancreatic Cancer.2018
- Author(s)
  Koikawa K, Ohuchida K, Yonenaga A, Sagara A, Ando Y, Kibe S, Takesue S,Nakayama H, Iwamoto C, Shindo K, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  49th Annual Meeting of the APA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02880
[Presentation] Pancreatic organoids elucidate the new mechanisms of pancreatic cancer local invasion2017
- Author(s)
  Koikawa K, Ohuchida K, Ando Y, Kibe S, Nakayama H, Takesue S, Yan Z, Abe T, Okumura T, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Okabe Y, Ohtsuka T, Mizumoto K, Nakamura M
- Organizer
  The 48th Annual Meeting of The American Pancreatic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15621
[Presentation] オートファージは膵星細胞の活性化に関与しており、その抑制は膵癌の進展を制御する2017
- Author(s)
  仲田興平、遠藤翔、大内田研宙、水元一博、小田義直、橋爪誠、中村雅史
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15621
[Presentation] Novel role of peritoneal mesothelial cells that lead to pancreatic cancer peritoneal dissemination formation2016
- Author(s)
  Abe T, Ohuchida K, Kibe S, Ando Y, Nakayama H, Takesue S, Endo S, Koikawa K, Okumura T, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Nakamura M
- Organizer
  47th Annual Meeting of the American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15498
[Presentation] Autophagy Drives Pancreatic Stellate Cells Activation and Promotes Pancreatic Cancer.2016
- Author(s)
  Endo S,Nakata K,Ohuchida K,Ando Y,Kibe S,Takesue S,Nakayama H,Abe T,Koikawa K,Okumura T,Mizuuchi Y,Moriyama T,Miyasaka Y,Manabe T,Ohtsuka T,Nagai E,Mizumoto K,Oda Y,Nakamura M
- Organizer
  47th Annual Meeting of the American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15621
[Presentation] 膵癌の癌関連線維芽細胞におけるオートファジーの役割2016
- Author(s)
  遠藤翔、仲田興平、大内田研宙、阿部俊也、肥川和寛、奥村隆志、佐田政史、堀岡宏平、水内祐介、大塚隆生、植木隆、永井英司、水元一博、小田義直、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪市
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15K15498
[Presentation] 膵癌の癌関連線維芽細胞におけるオートファジーの役割2016
- Author(s)
  遠藤翔、仲田興平、大内田研宙、阿部俊也、肥川和寛、奥村隆志、佐田政史、堀岡宏平、水内祐介、大塚隆生、植木隆、永井英司、水元一博、小田義直、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪市
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-25293287
[Presentation] 膵癌の癌関連線維芽細胞におけるオートファジーの役割2016
- Author(s)
  遠藤翔、仲田興平、佐田政史、大内田研宙、阿部俊也、肥川和寛、奥村隆志、佐田政史、堀岡宏平、水内祐介、大塚隆生、植木隆、永井英司、水元一博、小田義直、中村雅史
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪市）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-25713050
[Presentation] Endo180 regulate phosphorylation of myosin light chain 2 activity and increase the ability of extracellular matrix remodeling in leading pancreatic stellate cells.2016
- Author(s)
  Koikawa K, Ohuchida K, Kibe S, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Okumura T, Moriyama T, Nakata K, Miyasaka Y, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Nakamura M.
- Organizer
  47th Annual Meeting of the American Pancreatic Association
- Place of Presentation
  Boston(USA)
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15498
[Presentation] オートファジーが膵癌の癌間質相互作用に与える影響の検討2015
- Author(s)
  遠藤翔、仲田興平、大内田研宙、阿部俊也、肥川和寛、堀岡宏平、水内祐介、小田義直、水元一博、田中雅夫
- Organizer
  第46回日本膵臓学会大会
- Place of Presentation
  名古屋市
- Year and Date
  2015-06-19
- Data Source
  KAKENHI-PROJECT-25713050
[Presentation] オートファジーが膵癌の癌間質相互作用に与える影響の検討2015
- Author(s)
  遠藤翔、仲田興平、大内田研宙、阿部俊也、肥川和寛、堀岡宏平、水内祐介、小田義直、水元一博、田中雅夫
- Organizer
  第46回日本膵臓学会大会
- Place of Presentation
  名古屋市
- Year and Date
  2015-06-19
- Data Source
  KAKENHI-PROJECT-26670607
[Presentation] 膵癌関連繊維芽細胞におけるCD146発現と膵がんの進展抑制2014
- Author(s)
  鄭彪、大内田研宙、崔林、水内祐介、藤原謙次、赤川進、堀岡宏平、田中友晴、佐田政史、仲田興平、前山良、大塚隆生、小田義直、水元一博、田中雅夫
- Organizer
  第45回日本膵臓学会大会
- Place of Presentation
  北九州市
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-25293287
[Presentation] トラニラストによる膵星細胞の抑制についての検討2014
- Author(s)
  田中友晴、大内田研宙、水元一博、奥村隆志、千々岩芳朗、吉田真樹、佐田政史、堀岡宏平、鄭彪、赤川進、藤原謙次、仲田興平、宮坂義浩、前山良、大塚隆生、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-25293287
[Presentation] 膵癌におけるTM4SF1発現の意義2014
- Author(s)
  鄭彪、崔林、大内田研宙、進藤幸治、藤原謙次、赤川進、堀岡宏平、田中友晴、佐田政史、吉田真樹、千々岩芳朗、奥村隆志、仲田興平、大塚隆生、小田義直、水元一博、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-26670607
[Presentation] 膵癌の肝転移におけるfollistatin-like1の役割2014
- Author(s)
  堀岡宏平、大内田研宙、江口大樹、佐田政史、田中友晴、赤川進、藤原謙次、鄭彪、仲田興平、宮坂義浩、前山良、大塚隆生、水元一博、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-26670607
[Presentation] 膵癌の肝転移におけるfollistatin-like1の役割2014
- Author(s)
  堀岡宏平、大内田研宙、江口大樹、佐田政史、田中友晴、赤川進、藤原謙次、鄭彪、仲田興平、宮坂義浩、前山良、大塚隆生、水元一博、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-25670587
[Presentation] 膵癌の肝転移・腹膜播種巣における癌関連繊維芽細胞の機能解析2014
- Author(s)
  赤川進、大内田研宙、大塚隆生、寅田信博、藤原謙次、仲田興平、宮坂義浩、前山良、水元一博、田中雅夫
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-25293287
[Presentation] Salinomycin induced Autophagy and is Related with its Killing Effect for Pancreatic Cells2013
- Author(s)
  K Nakata, et al
- Organizer
  American Pancreatic Association, 44th Annual Meeting
- Place of Presentation
  Miami
- Year and Date
  2013-10-31
- Data Source
  KAKENHI-PROJECT-24659615
[Presentation] Salinomycin induced autophagy in pancreatic cancer cells and related with its cell killing effect
- Author(s)
  Nakata K et al
- Organizer
  44th Annual meeting of the American pancreatic association
- Place of Presentation
  Miami, USA
- Data Source
  KAKENHI-PROJECT-24659615
[Presentation] Salinomycin induced Autophagy and is Related with its Killing Effect for Pancreatic Cells
- Author(s)
  Nakata K
- Organizer
  Ammerican Pancreatic Association, 44th Annual Meeting
- Place of Presentation
  Miami, USA
- Data Source
  KAKENHI-PROJECT-25670587
[Presentation] Salinomycin induced Autophagy and is Related with its Killing Effect for Pancreatic Cells
- Author(s)
  Nakata K
- Organizer
  Ammerican Pancreatic Association, 44th Annual Meeting
- Place of Presentation
  Miami, USA
- Data Source
  KAKENHI-PROJECT-25293287

1. MIYASAKA Yoshihiro (40507795)

# of Collaborated Projects: 8 results

# of Collaborated Products: 20 results
2. OHUCHIDA Kenoki (20452708)

# of Collaborated Projects: 5 results

# of Collaborated Products: 40 results
3. NAGAI Eishi (30264021)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
4. EGAMI Takuya (40507787)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. SHIRAHANA Kengo (10529803)

# of Collaborated Projects: 3 results

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6. MAEYAMA Ryo (10611668)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
7. 池永直樹 (90759755)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
8. TANAKA Masao (30163570)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. TOMA Hiroki (80437780)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MIZUMOTO Kazuhiro (90253418)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. 進藤幸治 (00788432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
12. 中村雅史 (30372741)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
13. 藤田逸人 (40611281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 冨永洋平 (90304823)

# of Collaborated Projects: 1 results

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15. 森泰寿 (50632642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
16. 貞苅良彦 (80784503)

# of Collaborated Projects: 1 results

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17. 井上重隆 (00529802)

# of Collaborated Projects: 1 results

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18. 鬼丸学 (80529876)

# of Collaborated Projects: 1 results

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19. 大塚隆生 (20372766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 森山大樹 (70586859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
21. 岩本千佳 (10752842)

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22. 水内祐介 (20849088)

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23. 中山宏道 (80866773)

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24. 堀岡宏平 (10783699)

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25. OKUMURA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. ENDO Sho

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
27. KOIKAWA Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. TAKESUE Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. MIURA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. KUBO Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 森健策

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
32. 橋爪誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
33. 村田正治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 小田義直

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
35. 真鍋達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. 寅田信博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 三好圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakata Kohei 仲田 興平

NAKATA Kohei 仲田 興平

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膵星細胞活性化におけるオートファジーを標的としたHIT化合物の同定とその評価Principal Investigator

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New drug discovery screening targeting autophagyPrincipal Investigator

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Elucidation of the role of microRNA as a cancer treatment-resistant mechanism by autophagyPrincipal Investigator

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Elucidation of G0 phase maintenance mechanism by autophagy in cancer stem cells and development of artificial virus therapy methodPrincipal Investigator

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The role of autophagy in tumor-stromal cell interactionPrincipal Investigator

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Nakata Kohei 仲田興平

NAKATA Kohei 仲田興平