Nagayoshi Kinuko 永吉絹子

… Alternative Names

NAGAYOSHI Kinuko 永吉絹子

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Researcher Number	90761015
Other IDs
Affiliation (Current)	2025: 九州大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help	2019 – 2025: 九州大学, 大学病院, 助教 2017 – 2018: 九州大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related / Medium-sized Section 8:Sociology and related fields / Digestive surgery / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50010:Tumor biology-related / Basic Section 09070:Educational technology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator 大腸癌 / 空間トランスクリプトミクス解析 / scRNA-seq解析 / 腫瘍免疫抑制環境の構築 / Tr1細胞 / single cell RNA sequence / 腸内細菌叢 / CMS / scRNA-seq / 免疫微小環境 … More / CMS分類 / microbiome / Single cell RNA sequence / 癌微小環境 / heterogeneity / PDXモデル / 腫瘍不均一性 / 肝転移 / 間質 / oxaliplatin (L-OHP) / 抗癌剤耐性 / Spring-8 / 腫瘍内分布 / SPring-8 / 蛍光X線分析 / 治療効果予測 / 治療抵抗性 / 白金製剤 / oxaliplatin … More Except Principal Investigator 膵癌 / 微小環境 / 大腸癌 / 腫瘍免疫 / 腫瘍微小環境 / 消化器癌 / scRNA-seq / 免疫微小環境 / シングルセル解析 / 高度専門職 / 精神的健康度 / 労働衛生的視点 / キャリア継続 / 女性医療人 / 癌間質相互作用 / exosome / 肝転移 / 免疫抑制 / 腎移植 / 空間的遺伝子発現解析 / 血液循環腫瘍細胞 / signature gene / シングルセル遺伝子発現解析 / 肥満 / metabolism / 癌関連線維芽細胞 / 膵星細胞 / 神経内分泌経路 / 癌免疫微小環境 / ゲノムワイドスクリーニング / 樹状細胞 / 癌微小環境 / 免疫療法 / Genom wide screening / CRISPR-Cas9 / 樹状細胞(DC) / オルガノイド / 腫瘍関連好中球 / マイクロバイオーム / e-learning / オンデマンド / 医療教育 / 遠隔医療 / 360度カメラ / 医療体制 / 多様な働き方 / 職場環境 / 医療職 / 海外研究 / キャリアの継続 / 医療環境の国際比較 / 働き方改革 / 持続可能な医療体制 / 治療抵抗性 / 免疫逃避機構 / 免疫チェックポイント阻害剤 / CTLA4 / PD-L1 / 免疫チェックポイント / 免疫逃避 / シングルセル発現解析 / heterogeneity / 食道癌 / 胃癌 / 縦断調査 / 女性医療職者 / タンパク解析 / DNA/RNA解析 / 門脈系血液中マーカー解析 / タンパク / RNA / 大腸癌肝転移 / 化学療法抵抗性 / 蛍光分析 / 抗癌剤耐性 / 腹膜播種 Less

大腸癌Coldサブタイプにおけるcytotoxic Tr1による免疫抑制環境の構築Principal Investigator
- Principal Investigator
  
  永吉絹子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
腎移植後大腸癌の発癌と腫瘍免疫システムの解明：免疫抑制薬のジレンマ克服を目指して
- Principal Investigator
  
  田村公二
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Development of on-demand medical teaching materials using 360 degree videos
- Principal Investigator
  
  久田由紀子
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 09070:Educational technology-related
- Research Institution
  Kyushu University
網羅的解析による膵癌免疫抑制環境メカニズムの解明
- Principal Investigator
  
  三好圭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyushu University
膵癌免疫微小環境-神経内分泌ネットワークの解明による免疫抑制解除への挑戦
- Principal Investigator
  
  坂井寛
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
核内transcriptomeから解明する肥満大腸がん患者のmetabolism
- Principal Investigator
  
  藤田逸人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
scRNAseqによる血液循環腫瘍細胞検出と腫瘍内空間的トランスクリプトミクス
- Principal Investigator
  
  進藤幸治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
腸内細菌叢による大腸癌subtypingとその免疫微小環境のscRNAseq解析Principal Investigator
- Principal Investigator
  
  永吉絹子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
マイクロバイオームと腫瘍関連好中球から見た膵がんミニエコシステム
- Principal Investigator
  
  池永直樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
Development of an international survey and research on diverse work styles of healthcare professionals toward a sustainable healthcare system
- Principal Investigator
  
  Chishaki Akiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 8:Sociology and related fields
- Research Institution
  Fukuoka Nursing College
Elucidation of the mechanism of anti-tumor effect by disabling the immune escape mechanism and development of treatment based on regulation of the pancreatic cancer microenvironment
- Principal Investigator
  
  ONIMARU Manabu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
Elucidation of Tumor Heterogeneity and Treatment Resistance Mechanisms Using PDX Model Library of Colorectal Cancer MetastasesPrincipal Investigator
- Principal Investigator
  
  NAGAYOSHI Kinuko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyushu University
Tracking the transition of a decade of career continuity among women medical professionals
- Principal Investigator
  
  CHISYAKI Akiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 8:Sociology and related fields
- Research Institution
  Fukuoka Nursing College
  Fukuoka Dental College
  Kyushu University
Analysis of single-cell transcriptome with Drop-seq for heterogeneity in the tumor microenvironment derived from digestive cancers.
- Principal Investigator
  
  OHUCHIDA Kenoki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
Quantitative evaluation of the intratumoral distribution of platinum in colorectal cancer via synchrotron radiation X-ray fluorescence spectrometryPrincipal Investigator
- Principal Investigator
  
  NAGAYOSHI Kinuko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Elucidation of microenvironment induction mechanism by exosome in liver metastasis and peritoneal dissemination of colorectal cancer
- Principal Investigator
  
  FUJITA Hayato
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
RNA / protein analysis in portal blood exosomes to detect a high risk group of colorectal cancer liver metastases
- Principal Investigator
  
  SADAKARI Yoshihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Microenvironmental changes in familial adenomatous polyposis during colorectal cancer carcinogenesis2024
- Author(s)
  Hisano Kyoko、Mizuuchi Yusuke、Ohuchida Kenoki、Kawata Jun、Torata Nobuhiro、Zhang Jinghui、Katayama Naoki、Tsutsumi Chikanori、Nakamura Shoichi、Okuda Sho、Otsubo Yoshiki、Tamura Koji、Nagayoshi Kinuko、Ikenaga Naoki、Shindo Koji、Nakata Kohei、Oda Yoshinao、Nakamura Masafumi
- Journal Title
  
  Cancer Letters
  
  Volume: 589 Pages: 216822-216822
- DOI
  10.1016/j.canlet.2024.216822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07283, KAKENHI-PROJECT-23K08093, KAKENHI-PROJECT-21K08713, KAKENHI-PROJECT-22K16447
[Journal Article] Relationship between job stress by effort-reward imbalance and work-related and medical accidents among medical professionals at university hospitals in Japan2023
- Author(s)
  NISHIKITANI Mariko、IZUKURA Rieko、SAWATARI Hiroyuki、A. KIDO Mizuho、MORIYA Fukuko、KAWANAMI Shoko、YASUMOTO Sawa、TAKETOMI Kikuko、FUJINO Yuriko、NAGAYOSHI Kinuko、KATO Kiyoko、NAKASHIMA Naoki、CHISHAKI Akiko
- Journal Title
  
  Journal of Occupational Safety and Health
  
  Volume: 16 Issue: 2 Pages: 117-125
- DOI
  10.2486/josh.JOSH-2023-0004-GE
- ISSN
  1882-6822, 1883-678X
- Year and Date
  2023-09-30
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18462, KAKENHI-PROJECT-23K24665
[Journal Article] Quantitative evaluation of the intratumoral distribution of platinum in oxaliplatin‐treated rectal cancer: In situ visualization of platinum via synchrotron radiation X‐ray fluorescence spectrometry.2019
- Author(s)
  Ryo Koba Hayato Fujita Maiko Nishibori Kiyoshi Saeki Kinuko Nagayoshi Yoshihiko Sadakari Shuntaro Nagai Oki Sekizawa Kiyofumi Nitta Tatsuya Manabe Takashi Ueki Tatsuhiro Ishida Yoshinao Oda Masafumi Nakamura
- Journal Title
  
  International Journal of Cancer
  
  Volume: 146 Issue: 9 Pages: 2498-2509
- DOI
  10.1002/ijc.32592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10636, KAKENHI-PROJECT-17K10637, KAKENHI-PROJECT-18K16367
[Presentation] FAP発癌過程におけるTregの免疫抑制能の変化2023
- Author(s)
  久野恭子、水内祐介、大内田研宙、片山直樹、堤　親範、中村祥一、奥田　翔、大坪慶志輝、寅田信博、佐田政史、田村公二、永吉絹子、中村雅史
- Organizer
  第123回日本外科学会定期学術学会
- Data Source
  KAKENHI-PROJECT-22K07283
[Presentation] Single cell RNA sequenceを用いた家族性大腸腺腫症各発癌段階のmyeloid cellの比較2023
- Author(s)
  久野恭子、水内祐介、大内田研宙、孫起和、片山直樹、堤親範、寅田信博、藤本崇聡、田村公二、永吉絹子、中村雅史
- Organizer
  第44回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-22K07283
[Presentation] Single cell RNA sequenceを用いた家族性大腸腺腫症各発がん段階のCD4+ Tcellの比較2022
- Author(s)
  久野恭子、水内祐介、大内田研宙、堤親範、中村祥一、奥田翔、大坪慶志輝、寅田信博、佐田政史、田村公二、永吉絹子、進藤幸治、仲田興平、森山大樹、中村雅史
- Organizer
  第29回日本消化器関連学会週間（JDDW 2021）
- Data Source
  KAKENHI-PROJECT-22K07283
[Presentation] Single cell RNA sequenceを用いた家族性大腸腺腫症におけるmacrophageのheterogeneityの解明2021
- Author(s)
  久野恭子、水内祐介、大内田研宙、中村祥一、奥田翔、大坪慶志輝、佐田政史、永吉絹子、寅田信博、進藤幸治、仲田興平、森山大樹、永井俊太郎、中村雅史
- Organizer
  第29回日本消化器関連学会週間（JDDW 2021）
- Data Source
  KAKENHI-PROJECT-20K07678
[Presentation] 大学病院における医療職者の働き方と健康・安全との関係2021
- Author(s)
  錦谷まりこ，城戸瑞穂，中川朋子，安元佐和，守屋普久子，川波祥子，武冨貴久子，藤野ユリ子，永吉絹子，伊豆倉理江子，加藤聖子，中島直樹，樗木晶子
- Organizer
  第37回日本ストレス学会
- Data Source
  KAKENHI-PROJECT-21K18462
[Presentation] Single cell RNA sequenceを用いた家族性大腸腺腫症におけるmacrophageのheterogeneityの解明2021
- Author(s)
  久野恭子、水内祐介、大内田研宙、中村祥一、奥田翔、大坪慶志輝、佐田政史、永吉絹子、寅田信博、進藤幸治、仲田興平、森山大樹、永井俊太郎、中村雅史
- Organizer
  第29回日本消化器関連学会週間（JDDW 2021）
- Data Source
  KAKENHI-PROJECT-20K16360
[Presentation] 大学病院における医療職者の働き方と健康・安全との関係2021
- Author(s)
  錦谷まりこ，城戸瑞穂，中川朋子，安元佐和，守屋普久子，川波祥子，武冨貴久子，藤野ユリ子，永吉絹子，伊豆倉理江子，加藤聖子，中島直樹，樗木晶子
- Organizer
  第37回日本ストレス学会
- Data Source
  KAKENHI-PROJECT-19K21724
[Presentation] ダイバーシティ時代の女性医師の育成と支援　九州大学病院のキャリア支援策と当科における女性外科医師支援の現状と取り組み;2020
- Author(s)
  永吉絹子, 樗木晶子, 藤田逸人, 永井俊太郎, 武冨貴久子, 藤野ユリ子, 中村雅史, 赤司浩一, 石橋達朗
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K21724
[Presentation] 九州大学病院のキャリア継続支援策・きらめきプロジェクトの13年間を振り返って2020
- Author(s)
  永吉絹子, 樗木晶子, 中村雅史, 赤司浩一, 石橋達朗
- Organizer
  第115回日本消化器病学会九州支部例会・第109回日本消化器内視鏡学会九州支部例会
- Data Source
  KAKENHI-PROJECT-19K21724
[Presentation] 腫瘍間質における直腸癌L-OHP抵抗性の誘導：放射光蛍光X線を用いた白金分布分析2019
- Author(s)
  木庭遼、藤田逸人、西堀麻衣子、永吉絹子、貞苅良彦、永井俊太郎、関澤央輝、新田清文、大内田研宙、大塚隆生、植木隆、石田竜弘、中村雅史
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K16367
[Presentation] 腫瘍間質における直腸癌L-OHP抵抗性の誘導：放射光蛍光X線を用いた白金分布分析2019
- Author(s)
  木庭遼、藤田逸人、西堀麻衣子、永吉絹子、貞苅良彦、永井俊太郎、関澤央輝、新田清文、大内田研宙、大塚隆生、植木隆、石田竜弘、中村雅史
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10637
[Presentation] Stage IV大腸癌に対する外科的治療の役割2019
- Author(s)
  藤田逸人、木庭遼、永吉絹子、貞苅良彦、永井俊太郎、大内田研宙、大塚隆生、中村雅史
- Organizer
  第119回日本外科学会
- Data Source
  KAKENHI-PROJECT-17K10636
[Presentation] Oxaliplatin投与後の大腸癌組織における蛍光X線分析－組織内の白金分布と治療効果との関連性の検討－2019
- Author(s)
  木庭遼、藤田逸人、西堀麻衣子、永吉絹子、貞苅良彦、永井俊太郎、関澤央輝、新田清文、大内田研宙、大塚隆生、植木隆、石田竜弘、中村雅史
- Organizer
  日本分析化学会第79回分析化学討論会
- Data Source
  KAKENHI-PROJECT-17K10636
[Presentation] Oxaliplatin投与後の大腸癌組織における蛍光X線分析－組織内の白金分布と治療効果との関連性の検討－2019
- Author(s)
  木庭遼、藤田逸人、西堀麻衣子、永吉絹子、貞苅良彦、永井俊太郎、関澤央輝、新田清文、大内田研宙、大塚隆生、植木隆、石田竜弘、中村雅史
- Organizer
  日本分析化学会第79回分析化学討論会
- Data Source
  KAKENHI-PROJECT-17K10637
[Presentation] 腫瘍間質における直腸癌L-OHP抵抗性の誘導：放射光蛍光X線を用いた白金分布分析2019
- Author(s)
  木庭遼、藤田逸人、西堀麻衣子、永吉絹子、貞苅良彦、永井俊太郎、関澤央輝、新田清文、大内田研宙、大塚隆生、植木隆、石田竜弘、中村雅史
- Organizer
  第119回日本外科学会
- Data Source
  KAKENHI-PROJECT-17K10636
[Presentation] Oxaliplatin投与後の大腸癌組織における蛍光X線分析－組織内の白金分布と治療効果との関連性の検討－2019
- Author(s)
  木庭遼、藤田逸人、西堀麻衣子、永吉絹子、貞苅良彦、永井俊太郎、関澤央輝、新田清文、大内田研宙、大塚隆生、植木隆、石田竜弘、中村雅史
- Organizer
  日本分析化学会第79回分析化学討論会
- Data Source
  KAKENHI-PROJECT-18K16367
[Presentation] Stage IV大腸癌症例に対する外科的治療戦略2018
- Author(s)
  藤田逸人、永吉絹子、貞苅良彦、永井俊太郎、大内田研宙、大塚隆生、中村雅史
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10636
[Presentation] Oxaliplatin投与後直腸癌における組織中の白金分布と抗腫瘍効果との関連性の検討2018
- Author(s)
  木庭遼、植木隆、西堀麻衣子、石田竜弘、永吉絹子、貞苅良彦、藤田逸人、永井俊太郎、大内田研宙、大塚隆生、中村雅史
- Organizer
  第55回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16367
[Presentation] Oxaliplatin投与後の直腸癌組織における蛍光X線分析を用いた金属元素の分布測定2018
- Author(s)
  木庭遼、植木隆、西堀麻衣子、石田竜弘、永吉絹子、藤田逸人、永井俊太郎、大内田研宙、大塚隆生、中村雅史
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10636

1. 森山大樹 (70586859)

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2. FUJITA Hayato (40611281)

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3. 佐田政史 (10783508)

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4. CHISYAKI Akiko (60216497)

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5. SADAKARI Yoshihiko (80784503)

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6. 錦谷まりこ (40327333)

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8. 伊豆倉理江子 (80805292)

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9. 寅田信博 (00398075)

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13. OHUCHIDA Kenoki (20452708)

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14. ONIMARU Manabu (80529876)

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15. 城戸瑞穂 (60253457)

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16. 守屋普久子 (80449917)

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17. 武冨貴久子 (80543412)

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18. 藤野ユリ子 (90320366)

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23. 川波祥子 (70449940)

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24. 樗木浩朗 (70607093)

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26. 森山智彦 (20452758)

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31. 阿部俊也 (20722028)

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32. 木庭遼 (10866776)

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33. 久野恭子 (11003559)

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Nagayoshi Kinuko 永吉 絹子

NAGAYOSHI Kinuko 永吉 絹子

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大腸癌Coldサブタイプにおけるcytotoxic Tr1による免疫抑制環境の構築Principal Investigator

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腸内細菌叢による大腸癌subtypingとその免疫微小環境のscRNAseq解析Principal Investigator

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Elucidation of Tumor Heterogeneity and Treatment Resistance Mechanisms Using PDX Model Library of Colorectal Cancer MetastasesPrincipal Investigator

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Quantitative evaluation of the intratumoral distribution of platinum in colorectal cancer via synchrotron radiation X-ray fluorescence spectrometryPrincipal Investigator

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Nagayoshi Kinuko 永吉絹子

NAGAYOSHI Kinuko 永吉絹子