Yasuda Takahiko 安田貴彦

Researcher Number	20723977
Other IDs
Affiliation (Current)	2025: 独立行政法人国立病院機構(名古屋医療センター臨床研究センター), その他部局等, 分子診断研究室長
Affiliation (based on the past Project Information) *help	2018 – 2025: 独立行政法人国立病院機構(名古屋医療センター臨床研究センター), その他部局等, 分子診断研究室長 2016 – 2017: 独立行政法人国立病院機構(名古屋医療センター臨床研究センター), その他部局等, その他
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Tumor biology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Basic Section 49030:Experimental pathology-related
Keywords	Principal Investigator RNA-seq / AYA / 急性リンパ性白血病 / ゲノム / サブタイプ / B-ALL / adult / IDH1/2 / CDX2 / メチル化 … More / subtype / acute leulemia / AID / RAG / 染色体転座 / breakpoint / 年齢依存的 / 融合遺伝子 / 同種造血幹細胞移植 / T細胞レパトア解析 / ドナー由来骨髄不全症候群 / 全エクソン解析 / ドナー由来 / 造血幹細胞移植 / 骨髄不全症候群 … More Except Principal Investigator 白血病 / リキッドバイオプシー / 悪性リンパ腫 / 融合遺伝子 / 急性リンパ性白血病 / クローン性造血 / 同種造血幹細胞移植 / RNA-seq / GSEA / ZNF384融合遺伝子 / CEBP-IGH / 転写標的探索 / 転写因子 / ドライバー / 急性リンパ性 / regulon / hidden driver / ドライバー遺伝子 / NGS / Droplet digital PCR / Liquid biopsy / 血管内リンパ腫 / 不明熱 / 網羅的遺伝子変異解析 / 微小残存病変 / 遺伝子変異解析 / 遺伝子異常 / 微少残存病変 / 遺伝子変異 / B細胞 / 多段階発癌 / マウスモデル / 転写因子ネットワーク / クロマチン免疫沈降 / CRLF2 / MEF2D Less

同種造血幹細胞移植後のドナー由来クローン性造血の体内動態とその臨床的意義の解明
- Principal Investigator
  
  今橋伸彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Hospital Organization Nagoya Medical Center
T細胞受容体由来環状DNAによる白血病発症機構の解明と新規がん遺伝子探索Principal Investigator
- Principal Investigator
  
  安田貴彦
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Hospital Organization Nagoya Medical Center
Mechanisms of establishment and maintenance of intractable lymphoblastic leukemia from the viewpoint of hidden drivers
- Principal Investigator
  
  都築忍
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Aichi Medical University
日本人に特徴的な白血病原性融合遺伝子の白血病発症機構の解明
- Principal Investigator
  
  早川文彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
Identification of New Subtypes and Elucidation of Molecular Pathogenesis in Adult B-Cell Acute Lymphoblastic LeukemiaPrincipal Investigator
- Principal Investigator
  
  Yasuda Takahiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Hospital Organization Nagoya Medical Center
Evaluation of minimal residual disease by liquid biopsy in malignant lymphoma for precise therapeutic stratification.
- Principal Investigator
  
  Tomita Akihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fujita Health University
悪性リンパ腫疑い不明熱患者に対するリキッドバイオプシーによる診断法の確立
- Principal Investigator
  
  岡本晃直
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fujita Health University
Study of pathogenic mechanism of age-dependent chromosome translocation in adult acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  Yasuda Takahiko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Hospital Organization Nagoya Medical Center
Deciphering leukemia development and maintenance from the perspective of functions of fusion genes
- Principal Investigator
  
  Tsuzuki Shinobu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Aichi Medical University
Molecular analysis of bone marrow failure syndrome modeled on donor derived bone marrow failure syndromePrincipal Investigator
- Principal Investigator
  
  Yasuda Takahiko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  National Hospital Organization Nagoya Medical Center

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 白血病診療の実際2017
- Author(s)
  安田貴彦
- Total Pages
  208
- Publisher
  日本医師会雑誌
- Data Source
  KAKENHI-PROJECT-16K20973
[Book] Annual Review 20162016
- Author(s)
  安田貴彦
- Total Pages
  234
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-16K20973
[Book] AYA世代ALLのゲノム異常2016
- Author(s)
  安田貴彦
- Total Pages
  211
- Publisher
  腫瘍内科
- Data Source
  KAKENHI-PROJECT-16K20973
[Journal Article] Clonal hematopoiesis of a novel dic(18;20) clone following allogeneic hematopoietic stem cell transplantation2023
- Author(s)
  Ito Makoto、Fukushima Nobuaki、Fujii Tomoki、Numata Masaya、Morikawa Shiori、Kawamura Yuma、Goto Miyo、Kohno Akio、Imahashi Nobuhiko、Yasuda Takahiko、Sanada Masashi、Ishikawa Yuichi、Kiyoi Hitoshi、Ozeki Kazutaka
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 1 Pages: 80-87
- DOI
  10.1007/s12185-023-03673-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-23K27624
[Journal Article] EBF1-JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity.2023
- Author(s)
  Kojima Y, Kawashima F, Yasuda T, et al.
- Journal Title
  
  Int J Hematol.
  
  Volume: in press Issue: 1 Pages: 65-74
- DOI
  10.1007/s12185-023-03585-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24362, KAKENHI-PROJECT-23K15298, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-23K27624
[Journal Article] Leukaemic cells expressing ETV6::FRK are sensitive to dasatinib in vivo2023
- Author(s)
  Mayumi Azusa、Imamura Toshihiko、Yoshida Hideki、Osone Shinya、Yasuda Takahiko、Iehara Tomoko
- Journal Title
  
  eJHaem
  
  Volume: - Issue: 3 Pages: 751-755
- DOI
  10.1002/jha2.701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07759, KAKENHI-PROJECT-21K08384
[Journal Article] Suppression of super-enhancer-driven TAL1 expression by KLF4 in T-cell acute lymphoblastic leukemia2023
- Author(s)
  Noura Mina、Matsuo Hidemasa、Yasuda Takahiko、Tsuzuki Shinobu、Kiyoi Hitoshi、Hayakawa Fumihiko
- Journal Title
  
  Oncogene
  
  Volume: 43 Issue: 6 Pages: 447-456
- DOI
  10.1038/s41388-023-02913-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15298, KAKENHI-PROJECT-22K08475, KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-23K27624
[Journal Article] BCL6 inhibition ameliorates resistance to ruxolitinib in <i>CRLF2</i>-rearranged acute lymphoblastic leukemia2022
- Author(s)
  Tsuzuki Shinobu、Yasuda Takahiko、Goto Hiroaki、Maeda Naoko、Akahane Koshi、Inukai Takeshi、Yamamoto Hideyuki、Karnan Sivasundaram、Ota Akinobu、Hyodo Toshinori、Konishi Hiroyuki、Hosokawa Yoshitaka、Kiyoi Hitoshi、Hayakawa Fumihiko
- Journal Title
  
  Haematologica
  
  Volume: 108 Issue: 2 Pages: 394-408
- DOI
  10.3324/haematol.2022.280879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08426, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-23K24118, KAKENHI-PROJECT-23K24298, KAKENHI-PROJECT-23K24362
[Journal Article] Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2and IDH1/2 mutations2022
- Author(s)
  Yasuda Takahiko、Ogawa Seishi, et al.
- Journal Title
  
  Blood
  
  Volume: 139 Issue: 12 Pages: 1850-1862
- DOI
  10.1182/blood.2021011921
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K08723, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-22K08490
[Journal Article] Oncogenic lesions and molecular subtypes in adults with B‐cell acute lymphoblastic leukemia2022
- Author(s)
  Yasuda Takahiko、Sanada Masashi、Tsuzuki Shinobu、Hayakawa Fumihiko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 1 Pages: 8-15
- DOI
  10.1111/cas.15583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20K08723, KAKENHI-PROJECT-23K24362
[Journal Article] Functional inhibition of MEF2 by C/EBP is a possible mechanism of leukemia development by <i>CEBP‐IGH</i> fusion gene2022
- Author(s)
  Odaira Koya、Yasuda Takahiko、Okada Kentaro、Shimooka Takuya、Kojima Yukino、Noura Mina、Tamura Shogo、Kurahashi Shingo、Iwamoto Eisuke、Sanada Masashi、Matsumura Itaru、Miyazaki Yasushi、Kojima Tetsuhito、Kiyoi Hitoshi、Tsuzuki Shinobu、Hayakawa Fumihiko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 3 Pages: 781-792
- DOI
  10.1111/cas.15641
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20K08723, KAKENHI-PROJECT-23K24362
[Journal Article] Genomic analysis of multiple myeloma using targeted capture sequencing in the Japanese cohort.2020
- Author(s)
  Kanamori T, Sanada M, Ri M, Ueno H, Nishijima D, Yasuda T, Tachita T, Narita T, Kusumoto S, Inagaki A, Ishihara R, Murakami Y, Kobayashi N, Shiozawa Y, Yoshida K, Nakagawa MM, Nannya Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Horibe K, Handa H, Ogawa S, Iida S.
- Journal Title
  
  Br J Haematol.
  
  Volume: - Issue: 5 Pages: 755-763
- DOI
  10.1111/bjh.16720
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10136, KAKENHI-PROJECT-18K16103, KAKENHI-PROJECT-20K08723, KAKENHI-PROJECT-20K08759, KAKENHI-PROJECT-19H05656
[Journal Article] Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia2020
- Author(s)
  Shinobu Tsuzuki, Takahiko Yasuda, Shinya Kojima, Masahito Kawazu, Koshi Akahane, Takeshi Inukai, Masue Imaizumi, Takanobu Morishita, Masashi Sanada,　Hideki Muramatsu, Yoshiyuki Takahashi, Yasushi Miyazaki, Itaru Matsumura, Hitoshi Kiyoi, Yoshitaka Hosokawa, Hiroyuki Mano, Fumihiko Hayakawa
- Journal Title
  
  Blood Cancer Discovery
  
  Volume: 1 Issue: 1 Pages: 82-95
- DOI
  10.1158/2643-3230.bcd-19-0080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02645, KAKENHI-PROJECT-20K06613, KAKENHI-PROJECT-17K07263
[Journal Article] Chromosomal translocation-mediated evasion from miRNA induces strong MEF2D fusion protein expression, causing inhibition of PAX5 transcriptional activity.2019
- Author(s)
  Hirano D, Hayakawa F, Yasuda T, Tange N, Yamamoto H, Kojima Y, Morishita T, Imoto N, Tsuzuki S, Mano H, Naoe T, Kiyoi H.
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 13 Pages: 2263-2274
- DOI
  10.1038/s41388-018-0573-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K16103, KAKENHI-PROJECT-18H02645, KAKENHI-PROJECT-18H02835
[Journal Article] Precision medicine in hematological malignancies2019
- Author(s)
  安田貴彦、堀部敬三
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 9 Pages: 1386-1395
- DOI
  10.11406/rinketsu.60.1386
- NAID
  130007724644
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16103
[Journal Article] ZNF384-fusion proteins have high affinity for the transcriptional coactivator EP300 and aberrant transcriptional activities.2019
- Author(s)
  3.Yamamoto H, Hayakawa F, Yasuda T, Odaira K, Minamikawa Y, Tange N, Hirano D,Kojima Y, Morishita T, Tsuzuki S, Naoe T, Kiyoi H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 593 Issue: 16 Pages: 2151-2161
- DOI
  10.1002/1873-3468.13506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K16103
[Journal Article] Transcriptional activities of DUX4 fusions in B-cell acute lymphoblastic leukemia2018
- Author(s)
  Tanaka Yosuke、Kawazu Masahito、Yasuda Takahiko、Tamura Miki、Hayakawa Fumihiko、Kojima Shinya、Ueno Toshihide、Kiyoi Hitoshi、Naoe Tomoki、Mano Hiroyuki
- Journal Title
  
  Haematologica
  
  Volume: 103 Issue: 11 Pages: 522-526
- DOI
  10.3324/haematol.2017.183152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K16103, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17J10130
[Journal Article] Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.2018
- Author(s)
  Li JF, Dai YT, Kubota Y, Kiyoi H, Matsumura I, Miyazaki Y, Olsson L, Tan AM, Ariffin H, Chen J, Takita J, Yasuda T, Mano H, Johansson B, Yang JJ, Yeoh AE, Hayakawa F, Chen Z, Pui CH, Fioretos T, Chen SJ, Huang JY.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 115 Issue: 50
- DOI
  10.1073/pnas.1814397115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19467, KAKENHI-PROJECT-18K16103, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-18H02835
[Journal Article] Acute lymphoblastic leukemia of adolescents and young adults: from the viewpoint of physicians2017
- Author(s)
  安田貴彦、早川文彦
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 58 Issue: 8 Pages: 1031-1037
- DOI
  10.11406/rinketsu.58.1031
- NAID
  130006067964
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20973
[Journal Article] Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency2017
- Author(s)
  Kawazu Masahito、Kojima Shinya、Ueno Toshihide、Totoki Yasushi、Nakamura Hiromi、Kunita Akiko et.al.
- Journal Title
  
  PLOS Genetics
  
  Volume: 13 Issue: 6 Pages: e1006853-e1006853
- DOI
  10.1371/journal.pgen.1006853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15611, KAKENHI-PROJECT-16K20973
[Journal Article] PAX5 tyrosine phosphorylation by SYK co-operatively functions with its serine phosphorylation to cancel the PAX5-dependent repression of BLIMP1: A mechanism for antigen-triggered plasma cell differentiation.2016
- Author(s)
  Inagaki Y, Hayakawa F, Hirano D, Kojima Y, Morishita T, Yasuda T, Naoe T, Kiyoi H
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 475 Issue: 2 Pages: 176-181
- DOI
  10.1016/j.bbrc.2016.05.067
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-16K20973
[Journal Article] Genomic characterization of primary central nervous system lymphoma2016
- Author(s)
  Fukumura K, D Kawazu M, Ueno T, Sai E, Soda M, Kojima S, Ueda H, Yasuda T, Yamaguchi H, Lee J, Shishido-Hara Y, Sasaki A, Shirahata M, Mishima K, Ichimura K, Mukasa A, Narita Y, Saito N, Aburatani H, Nishikawa R, Nagane M, Mano H
- Journal Title
  
  Acta Neuropathol
  
  Volume: publish online 12 Jan 2016 Issue: 6 Pages: 865-875
- DOI
  10.1007/s00401-016-1536-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462189, KAKENHI-PROJECT-26461155, KAKENHI-PROJECT-16K20973
[Journal Article] Recurrent DUX4 fusions in B-cell acute lymphoblastic leukemia of adolescents and young adults.2016
- Author(s)
  Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.
- Journal Title
  
  Nat Genet.
  
  Volume: 48 Issue: 12 Pages: 569-74
- DOI
  10.1038/ng1216-1587a
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K20973
[Journal Article] MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced by TGF-β2016
- Author(s)
  Katsura A, Suzuki HI, Ueno T, Mihira H, Yamazaki T, Yasuda T, Watabe T, Mano H, Yamada Y, Miyazono K.
- Journal Title
  
  Genes Cells
  
  Volume: 21 Issue: 1 Pages: 99-116
- DOI
  10.1111/gtc.12323
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-16K20973
[Journal Article] Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer2016
- Author(s)
  Ando M, Kawazu M, Ueno T, Koinuma D, Ando K, Koya J, Kataoka K, Yasuda T, Yamaguchi H, Fukumura K, Yamato A, Soda M, Sai E, Yamashita Y, Asakage T, Miyazaki Y, Kurokawa M, Miyazono K, Nimer SD, Yamasoba T, Mano H.
- Journal Title
  
  Cancer Res.
  
  Volume: 76 Issue: 7 Pages: 1814-1824
- DOI
  10.1158/0008-5472.can-14-3816
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-26461155, KAKENHI-PROJECT-16K20973
[Presentation] Functional analysis of EBF1-JAK2 fusion protein in B-cell acute lymphoblastic leukemia.2022
- Author(s)
  小嶋有希乃, 河島史華, 安田貴彦　他
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24362
[Presentation] Prospective Study of the Usefulness of Liquid Biopsy in Patients with Unknown Fever Suspected of Malignant Lymphoma2022
- Author(s)
  Akinao Okamoto, Masashi Sanada, Takahiko Yasuda, Seiichi Kato, Akihiro Tomita et al.
- Organizer
  64th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08381
[Presentation] Aberrantly Expressed C/EBPα in B Cells Functionally Inhibits MEF2 Family Transcription Factors: A Possible Mechanism of Leukemia Development by CEBP-IGH.2022
- Author(s)
  Koya Odaira, Takahiko Yasuda, Kentaro Okada, et al.
- Organizer
  12th AACR-JCA Joint Conference: Breakthroughs in Cancer Research.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24362
[Presentation] Aberrant expression of CEBPα inhibits MEF2 transcriptional activity in B cell acute lymphoblastic leukemia2022
- Author(s)
  大平晃也 (1) 、安田貴彦 (2) 、岡田健太郎 (1) 、下岡拓弥 (1) 小嶋有希乃 (1) 、田村彰吾 (1) 、小嶋哲人 (1,3) 、清井仁 (4) 、都築忍 (5) 、早川文彦 (1)
- Organizer
  第84回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08384
[Presentation] Prospective Study on the Usefulness of Liquid Biopsy in Patients with Unknown Fever Suspected of Malignant Lymphoma2022
- Author(s)
  Akinao Okamoto 1 , Masashi Sanada 2 , Takahiko Yasuda 2 , Akihiro Tomita 1
- Organizer
  ASH2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08384
[Presentation] Liquid biopsy for suspicious lymphoma patients with fever of unknown origin2022
- Author(s)
  Akinao Okamoto, Masashi Sanada, Takahiko Yasuda, Seiichi Kato, Akihiro Tomita et al.
- Organizer
  第84回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-21K08381
[Presentation] 初発時の遺伝子変異解析が病型診断に有用であったろ胞性ヘルパーT細胞表現型を有するPTCLの1例2021
- Author(s)
  加藤駿晴、岡本晃直、入山智沙子、安田貴彦、後藤尚絵、加留部謙之介、三好寛明、眞田昌、堀部敬三、冨田章裕
- Organizer
  第10回日本血液学会東海地方会　2021年4月、名古屋（優秀演題賞、口演）
- Data Source
  KAKENHI-PROJECT-21K08407
[Presentation] 悪性リンパ腫FFPE標本から抽出したゲノム検体を用いた網羅的変異解析の結果に影響を与える因子の検討2021
- Author(s)
  入山智沙子、安田貴彦、三好寛明、大島孝一、高橋直樹、塚崎邦弘、島田和之、平賀潤二、鏡味良豊、福原傑、伊豆津宏二、鈴木律朗、福原規子、楫屋良子、山本一仁、石田高司、小林幸夫、眞田昌、齋藤明子、齋藤俊樹、永井宏和、堀部敬三、冨田章裕
- Organizer
  第83回日本血液学会学術集会　2021年9月、仙台（口演）
- Data Source
  KAKENHI-PROJECT-21K08407
[Presentation] Novel Molecular pathogenesis and therapeutic target in acute erythroid leukemia.2019
- Author(s)
  Takashi Kanamori, Masashi Sanada, Dai Nishijima, Takahiko Yasuda
- Organizer
  Congress of the European Hematology Association (EHA24)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] 造血器腫瘍におけるプレシジョン・メディシン2019
- Author(s)
  安田貴彦
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] がん領域におけるクリニカルシーケンスのための臨床ゲノム情報データベースの開発2019
- Author(s)
  齋藤俊樹、安田貴彦、真田昌、永井宏和、堀部敬三
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] がん領域におけるクリニカルシーケンスのための臨床ゲノム情報データベースの開発2019
- Author(s)
  齋藤俊樹, 濱野康司, 山本松雄, 安田貴彦, 真田昌, 永井宏和, 堀部敬三
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] 成人B細胞性急性リンパ性白血病のゲノム学的・臨床的な特徴2018
- Author(s)
  安田貴彦, 西島大, 小島進也, 河津正人, 上野敏秀, 都築忍, 清井仁, 松村到, 宮崎泰司, 堀部敬三, 間野博行, 直江知樹, 眞田昌, 早川文彦
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] ZNF384-Fusion Proteins Have High Affinity to EP300, Which Increases Their Transcriptional Activities.2018
- Author(s)
  Hideyuki Yamamoto, Fumihiko Hayakawa, Takahiko Yasuda, Yuka Minamikawa, Naoyuki Tange, Daiki Hirano, Yuki Kojima, Takanobu Morishita, Shinobu Tsuzuki, Hiroyuki Mano, Tomoki Naoe and Hitoshi Kiyoi
- Organizer
  60th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] ZNF384融合遺伝子による急性リンパ性白血病発症機構の解明2018
- Author(s)
  山本秀行, 早川文彦, 安田貴彦, 南川友香, 丹下直幸, 平野大希, 小島勇貴, 森下喬允, 都築忍, 間野博行, 直江知樹, 清井仁
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] DUX4-IGH融合遺伝子陽性B細胞急性リンパ性白血病における転写活性解析2018
- Author(s)
  田中庸介, 河津正人, 安田貴彦, 早川文彦, 清井仁, 直江知樹, 間野博行
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] ZNF384融合遺伝子による急性リンパ性白血病発症機構の解明2018
- Author(s)
  山本秀行、早川文彦、安田貴彦、南川友香、丹下直幸、平野大希、小島勇貴、都築　忍、間野博行、直江知樹、清井仁
- Organizer
  第80回　日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02645
[Presentation] 成人B細胞性急性リンパ性白血病のゲノム学的・臨床的な特徴2018
- Author(s)
  安田貴彦、西島大、小島進也、河津正人、上野俊秀、都築忍、清井仁、松村到、宮崎泰司、堀部敬三、間野博行、直江知樹、真田昌、早川文彦
- Organizer
  第80回　日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02645
[Presentation] Genomic and Clinical Characterization of Adult Ph-Negative B-Cell Acute Lymphoblastic Leukemia2018
- Author(s)
  Takahiko Yasuda, Dai Nishijima, Shinya Kojima, Masahito Kawazu, Toshihide Ueno, Shinobu Tsuzuki, Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki, Keizo Horibe, Hiroyuki Mano, Tomoki Naoe, Masashi Sanada, Fumihiko Hayakawa
- Organizer
  60th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16103
[Presentation] High Expression of MEF2D-Fusion Protein Is Caused By Escaping from the Suppression By miRNA and Leads to Suppress Transcriptional Activity of PAX52017
- Author(s)
  Daiki Hirano, Fumihiko Hayakawa, Takahiko Yasuda, naoyuki Tange, Hideyuki Yamamoto, Yuki Kojima, Takanobu Morishita, Naoto Imoto, Shinobu Tsuzuki, Hiroyuki Mano, Tomoki Naoe, Hitoshi Kiyoi
- Organizer
  59th Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20973
[Presentation] The attempt to identify suitable MRD markers in acute lymphoblastic leukemia by next generation sequencing for practical use2017
- Author(s)
  MitsukoAkaihata,YukaIijima,DaiNishijima,TomomiIshida,Mika Fuyama, Masaya Koganesawa, Takahiko Yasuda, Masashi Sanada
- Organizer
  第５９回小児血液がん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K20973
[Presentation] MEF2D 融合タンパクはマイクロ RNA の制御を回避することで高発現になり PAX5 の転写活性を抑制する2017
- Author(s)
  Daiki Hirano, Fumihiko Hayakawa, Takahiko Yasuda, Hideyuki Yamamoto, Yuki Kojima, Takanobu Morishita, Naoto Imoto, Shinobu Tsuzuki, Hiroyuki Mano, Tomoki Naoe, Hitoshi Kiyoi
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K20973
[Presentation] 思春期・若年成人急性リンパ性白血病における新規融合型がん遺伝子DUX4-IGHの発見2016
- Author(s)
  安田貴彦、都築忍、河津正人、早川文彦、小島進也、上野敏秀、清井仁、直江知樹、間野博行
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-16K20973
[Presentation] AYA世代急性リンパ性白血病における網羅的融合遺伝子解析2016
- Author(s)
  安田貴彦、都築忍、河津正人、早川文彦、小島進也、上野敏秀、清井仁、直江知樹、間野博行
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-16K20973

1. Tsuzuki Shinobu (00342965)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Tomita Akihiro (80378215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 佐谷秀行 (80264282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 杉原英志 (50464996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 岡本晃直 (80775049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 真田昌 (20529044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 加藤省一 (30584669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 早川文彦 (30402580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 今橋伸彦 (90726861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SIVASUNDARAM Karnan

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. NAGANE Motoo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. SASAKI Nobuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. LEE Jeunghun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. KUNITA Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. IMAMURA Toshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 太田明伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 都筑忍

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
18. 上野敏秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 清井仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 渡部徹郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 宮園浩平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 能浦三奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yasuda Takahiko 安田 貴彦

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同種造血幹細胞移植後のドナー由来クローン性造血の体内動態とその臨床的意義の解明

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T細胞受容体由来環状DNAによる白血病発症機構の解明と新規がん遺伝子探索Principal Investigator

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Mechanisms of establishment and maintenance of intractable lymphoblastic leukemia from the viewpoint of hidden drivers

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日本人に特徴的な白血病原性融合遺伝子の白血病発症機構の解明

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Identification of New Subtypes and Elucidation of Molecular Pathogenesis in Adult B-Cell Acute Lymphoblastic LeukemiaPrincipal Investigator

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Evaluation of minimal residual disease by liquid biopsy in malignant lymphoma for precise therapeutic stratification.

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悪性リンパ腫疑い不明熱患者に対するリキッドバイオプシーによる診断法の確立

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Study of pathogenic mechanism of age-dependent chromosome translocation in adult acute lymphoblastic leukemiaPrincipal Investigator

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Deciphering leukemia development and maintenance from the perspective of functions of fusion genes

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Molecular analysis of bone marrow failure syndrome modeled on donor derived bone marrow failure syndromePrincipal Investigator

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[Book] 白血病診療の実際2017

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[Book] Annual Review 20162016

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[Book] AYA世代ALLのゲノム異常2016

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[Journal Article] Clonal hematopoiesis of a novel dic(18;20) clone following allogeneic hematopoietic stem cell transplantation2023

Yasuda Takahiko 安田貴彦

[Journal Article] BCL6 inhibition ameliorates resistance to ruxolitinib in <i>CRLF2</i>-rearranged acute lymphoblastic leukemia2022