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KAWAHARA Michio  河原 道夫

ORCIDConnect your ORCID iD *help
… Alternative Names

河原 道夫  カワハラ ミチオ

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Researcher Number 30034094
External Links
Affiliation (based on the past Project Information) *help 2007: Hiroshima University, Graduate School of Biomedical Sciences, Professor
2006: 広島大学, 大学院医歯薬学総合研究科, 教授
2002: Hiroshima University Graduate School of Biomedical Sciences, Dental Anesthesiology, Professor, 大学院・医歯薬学総合研究科, 教授
2001: 広島大学, 歯学部, 教授
1999: University Dental Hospital, Anesthesiology, Hiroshima University, Professor, 歯学部・附属病院, 教授 … More
1998: 広島大学, 歯学部・附属病院, 助手
1994: Hiroshima Univ. Dental Hosp.Prof., 歯学部・付属病院, 教授
1992 – 1994: 広島大学, 歯学部・附属病院, 教授
1989: 広島大学, 歯学部附属病院, 助教授 Less
Review Section/Research Field
Principal Investigator
外科・放射線系歯学 / Surgical dentistry
Except Principal Investigator
Functional basic dentistry / Functional basic dentistry / Surgical dentistry
Keywords
Principal Investigator
NO-711 / Gabaculine / GABA / ハロセン / Ketamine / Glutamate / microdialysis / Behavioral pharmacology / General anesthesia / 内因性GABA … More / 脳内GABA濃度 / GABA神経 / 正向反射 / 全身麻酔作用 / GABAculine / ケタミン / グルタミン酸 / 脳マイクロダイアリシス法 / 行動薬理学 / 全身麻酔 / Sevoflurance / Isoflurane / Halothane / Intracellular Ca^<2+> concentration / Isolated hepatocytes / Guinea pig / 細胞内CA^<2+>濃度 / セボフルラン / イソフルラン / 細胞内Ca^<2+>濃度 / 分離肝細胞 / モルモット / ニカルジピン / ジルチアゼム / ベラパミ-ル / カルシウム拮抗薬 / 肝障害 … More
Except Principal Investigator
MPP+ / L-DOPA / 正向反射 / Analgesia / Immobility / Unconsciousness / Glycine transporter inhibitor / α_2-Adrenergic receptor agonist / μ-Opioid receptor agonist / Behavioral pharmacology / General Anesthesia / 全身麻痺作用 / α2-アドレナリン受容体作動薬 / グリシン取り込み阻害薬 / オピオイド受容体作動薬 / α_2-アドレナリン受容体作動薬 / GABA / 鎮痛作用 / 不動化 / 全身麻酔作用 / Desipramine / Dopamine / Ibuprofen / Indomethacin / Monoamine transporter / Arachidonoc acid / 痙攣 / コカイン / リドカイン / シクロオキシゲナーゼ / モノアミントランスポーター / デシプラミン / ドパミン / アスピリン / インドメタシン / MPP^+ / モノアミントランスポータ / アラキドン酸 / General anesthetics / Kainic aci / N-methyl-D-aspartate / L-Allyglycine / Bicuculline / Muscimol / Excitatory amino acid receptors / GABAィイD2AィエD2 receptors / マイクロダイアリシス / プロポフォール / GABA神経 / 全身麻酔 / 全身麻酔薬 / カイニン酸 / NMDA / L-アリルグリシン / ビククリン / ムシモール / 興奮性アミノ酸受容体 / GABA_A受容体 / NITROUS-OXIDE / MIDAZOLAN / SEDATION / MIDAZOLAM / DENTAL / BIS / SEDATI0N Less
  • Research Projects

    (7 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (7 People)
  •  Clarification of mechanisms of analgesia and immobility induced by general anesthesia, and exploration of new anesthetic methods

    • Principal Investigator
      IRIFUNE Masahiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Hiroshima University
  •  Bispectral Index(BIS)による精神鎮静施行時の鎮静度評価の確立

    • Principal Investigator
      寳田 貫
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Hiroshima University
  •  Regulation of dopamine transporter function and its role in neuronal diseases - Regulation by arachidonic acid.

    • Principal Investigator
      DOHI Toshihiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  The Role of GABA and Glutamate Neurons in General Anesthetic ActionPrincipal Investigator

    • Principal Investigator
      KAWAHARA Michio, 入船 正浩
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  The role of GABA neurons in general anesthesia: an in vivo microdialysis study

    • Principal Investigator
      IRIFUNE Masahiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Hiroshima University
  •  Effects of Volatile Anesthetics on the Intracellular Ca^<2+> ConcentrationPrincipal Investigator

    • Principal Investigator
      KAWAHARA Michio
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  カルシウム拮抗薬のハロセン肝障害に及ぼす影響Principal Investigator

    • Principal Investigator
      河原 道夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Hiroshima University

All 2007

All Journal Article

  • [Journal Article] MK-801 enhances gabaculine-induced loss of the righting reflex in mice, but not immobility2007

    • Author(s)
      Irifune, M., Katayama, S., Takarada, T., Shimizu, Y., Endo, C., Takata, T., Morita, K., Dohi, T., Sato, T., Kawahara, M
    • Journal Title

      Can J Anaesth 54(12)

      Pages: 998-1005

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592037
  • [Journal Article] Increased gamma-aminobutyric acid levels in mouse brain induce loss of righting reflex, but not immobility, in response to noxious stimulation2007

    • Author(s)
      Katayama, S., Irifune, M., Kikuchi, N., Takarada, T., Shimizu, Y., Endo, C., Takata, T., Debi, T., Sato, T., Kawahara, M
    • Journal Title

      Anesth Analg 104(6)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592037
  • [Journal Article] Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice2007

    • Author(s)
      Irifune, M., Kikuchi, N., Saida, T., Takarada, T., Shimizu, Y., Endo, C., Morita, K., Dohi, T., Sato, T., Kawahara, M
    • Journal Title

      Anesth Analg 104(6)

      Pages: 1415-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592037
  • 1.  IRIFUNE Masahiro (10176521)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 2.  DOHI Toshihiro (00034182)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  藤井 宏融 (60034021)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KINUGAWA Hiroshi (00177883)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MORITA Katsuya (10116684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  寳田 貫 (70274107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  北山 滋雄 (80177873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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