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YOSHIKAWA Kazuaki  吉川 和明

ORCIDConnect your ORCID iD *help
Researcher Number 30094452
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013 – 2015: 大阪大学, たんぱく質研究所, 教授
2004 – 2012: 大阪大学, 蛋白質研究所, 教授
2007 – 2008: 大阪大学, たんぱく質研究所, 教授
2001: 大阪大学, 蛋白質研究所, 教授
1994 – 2001: 大阪大学, たんぱく質研究所, 教授 … More
1995: Osaka University, Institute for Protein Research, Professor, たんぱく質研修所, 教授
1994 – 1995: 大阪大学, 蛋白質研究所, 教授
1993: (財)東京都神経科学総合研究所, 分子神経生物学研究部門, 副参事研究員
1993: 東京都神経科学, 総合研究所, 副参事研究員
1992: (財)東京都神経研, 分子神経生物学研究部門, 副参事研究員
1992: 東京都神経科学総合研, 分子神経生物, 副強事研究員
1991: Dept. Molecular Biology, Director, 分子生物学研究部門, 副参事研究員
1989 – 1990: 東京都精神医学総合研究所, 副参事
1989: PRIT, Dept. of Molecular Biology, Chief, 分子生物学研究室, 副参事研究員
1988: 東京都精神医学総合研究所, 分子生物学研究室・研究部副参
1987: 東京都精神医学総合研究所, 分子生物学研究室, 副参事研究員 Less
Review Section/Research Field
Principal Investigator
Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Pathological medical chemistry / 広領域 / Neurochemistry/Neuropharmacology
Except Principal Investigator
General pharmacology / Neurochemistry/Neuropharmacology / Biological Sciences
Keywords
Principal Investigator
Necdin / ニューロン / Neurons / ゲノムインプリンティング / E2F1 / 遺伝子導入 / アポトーシス / 神経分化 / Apoptosis / Cell cycle … More / 細胞周期 / 遺伝子発現 / p53 / necdin / 胚性がん細胞 / 分化 / E2F / 細胞分裂終了 / Genomic imprinting / Prader-Willi syndrome / プラダー・ウイリ症候群 / アデノウイルスベクター / APP / Gene expression / Differentiation / amyloid protein / Alzheimer's disease / アルツハイマー病 / 転写因子 / エネルギー代謝 / プラダー・ウィリー症候群 / Sirtl / 視床下部 / 発現制御 / 分裂終了 / 細胞分裂 / プロモーター / Psychotropic agents / Second messenger systems / Glucocorticoids / Protein kinase C / Protein kinase A / Enkephalin / Cholecystokinin / 発達 / ステロイドホルモン / 中枢神経系 / mRNA / グルココルチコイド / 細胞内情報変換系 / エンケヘァリン前駆体 / 神経ペプチド / ソマトスタチン / サイクリックAMP / 遺伝子発現調節 / 神経ペプチド前駆体遺伝子 / 向精神作用物質 / 細胞内二次情報伝達系 / 糖質コルチコイド / プロテインキナ-ゼC / プロテインキナ-ゼA / エンケファリン / コレシストキニン / Neurotrophins / MAGE family / 脳発達 / MAGEファミリー蛋白質 / 神経栄養因子 / MAGEファミリー / Transcription repressor / Nuclear Matrix / Terminal differentiation / 細胞死 / 神経幹細胞 / 転写抑制因子 / 核マトリックス / 最終分化 / Genome imprinting / Proteasome / Neuron / プロテアソーム / Retinoblastoma protein / Cell differentiation / アデノウィルスベクター / 核蛋白質 / がん抑制遺伝子 / プラダー・ウィリ症候群 / レチノブラストーマ蛋白質 / 細胞分化 / gene transfer / brain / neurodegeneration / adenovirus vector / neurons / アデノウイルス / 培養細胞 / 脳病理 / 脳 / 神経変性 / アミロイドβ蛋白質 / Transcription factors / Promoter / Cell division / Gene transfer / 遺伝子 / 系統発生 / 個体発生 / 核 / P19細胞 / trans因子 / 転写制御因子 / 特異的cis配列 / 発生分化 / Degeneration / Aging / Neural differentiation / Teratoma cells / Gene transfection / アミロイド / ニュ-ロン変性 / ニュ-ロン / テラト-マ細胞 / アルツハイマ-病 / 変性 / 老化 / テラトーマ細胞 / アミロイド蛋白質 / 立体構造予測 / SUMO化 / 翻訳後修飾 / 酸化ストレス / 活性酸素種 / パーキンソン病 / ユビキチン化 / パーキンソン病モデル / 遺伝子変異マウス / PGC-1α / 神経変性疾患 / ミトコンドリア / 生存能 / NSE3 / 6複合体 / SMC5 / アセチル化 / FoxOl / SMC5/6複合体 / FoxO1 / 哺乳類ニューロン / DNA修復 / SMC5/ 6複合体 / Fox01 / Sirt1 / 蛋白質ネットワーク / Cdc2 / 小脳顆粒神経細胞 / 介在ニューロン / 大脳基底核原基 / 脳由来神経栄養因子 / 軸索伸長 / 接線方向移動 / 海馬 / Foxol / 大脳皮質 / 脳神経疾患 / 発生・分化 / 神経科学 / ゼブラフィシュ / 発現調節 … More
Except Principal Investigator
神経幹細胞 / アミロイド / アミロイド前駆体タンパク / 脳 / アルツハイマー病 / 成体脳神経細胞新生 / プラダー・ウィリー症候群 / 神経細胞 / Necdin / 選択的セロトニン再取り込み阻害薬 / 精神疾患 / 成体脳 / 神経細胞死 / 神経細胞新生 / MAGE / necdin / ニューロン死 / 成体ニューロン新生 / 細胞周期 / ショウジョウバエ / ニューロン / シナプス形成 / 細胞接着因子 / 神経特異的遺伝子 / 回路網形成 / 神経活動 / 神経特異遺伝子 / 神経細胞分化 / 薬物依存 / キンドリング / 転写調節因子 / 遺伝子発現 / 神経原線維変化 / 第21染色体 / アポリポタンパクE4 / 神経成長抑制因子 / ダウン症 / アポリポタンパクE / 第14染色体 / 連鎖解析 / ポジショナルクローニング / 家族性アルツハイマー病 / 神経 / 遺伝病 / 遺伝子 / 痴呆 / 老化 / アルツハイマ-病 / polymerase chain reaction / メッセンジャーRNA / cDNAライブラリー Less
  • Research Projects

    (19 results)
  • Research Products

    (48 results)
  • Co-Researchers

    (40 People)
  •  Strengthening mechanism of neuronal vitality by necdinPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Mechanisms maintaining neuronal survival via necdin-centered protein interaction networksPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Necdin/MAGE family-regulated neurogenesis and neuron death in the adult brain

    • Principal Investigator
      NISHIMURA Isao
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
      Osaka University
  •  Genomic imprinting-involved regulatory mechanisms of central nervous system developmentPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Necdin/MAGEファミリーによるニューロンの分裂終了・分化・生存の制御機構

    • Principal Investigator
      NISHIMURA Isao
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Regulatory mechanisms of neuronal apoptosis by necdin/MAGE proteinsPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Regulatory mechanisms of neuronal differentiation and death by necdinPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Studies on generation and differentiation of central neurons in association with postmitotic mechanismsPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Molecular cell-biological studies on differentiation and mitotic arrest of brain neuronsPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  胚性がん細胞を用いた中枢ニューロンの分化機構の解析Principal Investigator

    • Principal Investigator
      吉川 和明
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Establishment of Alzheimer model cell system and its application to therapeuticsPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  神経活動による遺伝子応答

    • Principal Investigator
      三木 直正
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Studies on the Mechanisms of Neurogenesis using Gene Transfer TechniquesPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
      Tokyo Metropolitan Institute for Neuroscience
  •  アルツハイマー病の分子遺伝学的研究

    • Principal Investigator
      辻 省次
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  神経特異遺伝子とその発現ー記憶の分子機構を目指してー

    • Principal Investigator
      MIKI Naomasa
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  アルツハイマ-病に関連した遺伝子異常の解析

    • Principal Investigator
      榊 佳之
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Molecular biological study on the mechanism of neuronal degeneration using teratoma cellsPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      Tokyo Institute of Psychiatry
  •  アルツハイマー病に関連した遺伝子異常の解析

    • Principal Investigator
      宮武 正
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  Molecular biological study on modulatory effects of psychotropic agents on biosynthesis and metabolism of neuropeptidesPrincipal Investigator

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Institute of Psychiatry

All 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2004 Other

All Journal Article Presentation

  • [Journal Article] Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells.2016

    • Author(s)
      Fujimoto, I., Hasegawa, K., Fujiwara, K., Yamada, M., Yoshikawa, K.
    • Journal Title

      Cellular Signalling

      Volume: 28 Issue: 2 Pages: 94-107

    • DOI

      10.1016/j.cellsig.2015.11.016

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26830047, KAKENHI-PROJECT-25440047, KAKENHI-PROJECT-24300134
  • [Journal Article] Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults.2016

    • Author(s)
      Hasegawa, K., Yasuda, T., Shiraishi, C., Fujiwara, K., Przedborski, S., Mochizuki, H., Yoshikawa, K.
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 10943-10943

    • DOI

      10.1038/ncomms10943

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830047, KAKENHI-PROJECT-25830053, KAKENHI-PROJECT-24300134
  • [Journal Article] Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase2014

    • Author(s)
      Gur, I., Fujiwara, K., Hasegawa, K., Yoshikawa, K.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 6 Pages: e99503-e99503

    • DOI

      10.1371/journal.pone.0099503

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300134, KAKENHI-PROJECT-25830053, KAKENHI-PROJECT-26830047
  • [Journal Article] Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex2014

    • Author(s)
      Minamide, R., Fujiwara, K., Hasegawa, K., Yoshikawa, K.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 1 Pages: e84460-e84460

    • DOI

      10.1371/journal.pone.0084460

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300134, KAKENHI-PROJECT-24890104, KAKENHI-PROJECT-25830053
  • [Journal Article] Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner2013

    • Author(s)
      Huang, Z., Fujiwara, K., Minamide, R., Hasegawa, K., Yoshikawa, K.
    • Journal Title

      Journal of Neuroscience

      Volume: 33 Issue: 25 Pages: 10362-10373

    • DOI

      10.1523/jneurosci.5682-12.2013

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24300134, KAKENHI-PROJECT-24890104, KAKENHI-PROJECT-25830053
  • [Journal Article] Early decline in progenitor diversity in the marmoset lateral ventricle2013

    • Author(s)
      Azim, K., Zweifel, S., Klaus, F., Yoshikawa, K., Amrein, I., Raineteau, O.
    • Journal Title

      Cerebral Cortex

      Volume: 23 Issue: 4 Pages: 922-931

    • DOI

      10.1093/cercor/bhs085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences2013

    • Author(s)
      Hansen, D., Lui, J., Flandin, P., Yoshikawa, K., Rubenstein, J., Alvarez-Buylla, A., Kriegstein, A.
    • Journal Title

      Nature Neuroscience

      Volume: 16 Issue: 11 Pages: 1576-1587

    • DOI

      10.1038/nn.3541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Necdin controls foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis2012

    • Author(s)
      Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K
    • Journal Title

      J Neurosci

      Volume: 32 Issue: 16 Pages: 5562-5572

    • DOI

      10.1523/jneurosci.0142-12.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300138, KAKENHI-PROJECT-23700445
  • [Journal Article] β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus2012

    • Author(s)
      Bluske, K. K., Vue, T. Y., Kawakami, Y., Taketo, M. M., Yoshikawa, K., Johnson, J. E., Nakagawa, Y.
    • Journal Title

      Development

      Volume: 139 Issue: 15 Pages: 2692-2702

    • DOI

      10.1242/dev.072314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Thyroid hormone signaling acts as a neurogenic switch by repressing Sox2 in the adult neural stem cell niche2012

    • Author(s)
      Lopez-Juarez, A., Remaud, S., Hassani, Z., Jolivet, P., Pierre Simons, J., Sontag, T., Yoshikawa, K., Price, J., Morvan-Dubois, G., Demeneix, B. A.
    • Journal Title

      Cell Stem Cell

      Volume: 10 Issue: 5 Pages: 531-543

    • DOI

      10.1016/j.stem.2012.04.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] BMP receptor 1A regulates development of hypothalamic circuits critical for feeding behavior2012

    • Author(s)
      Peng, C. Y., Mukhopadhyay, A., Jarrett, J. C., Yoshikawa, K., Kessler, J. A.
    • Journal Title

      Journal of Neuroscience

      Volume: 32 Issue: 48 Pages: 17211-17224

    • DOI

      10.1523/jneurosci.2484-12.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] 3-dimensional examination of the adult mouse subventricular zone reveals lineage-specific microdomains2012

    • Author(s)
      Azim, K., Fiorelli, R., Zweifel, S., Hurtado-Chong, A., Yoshikawa, K., Slomianka, L., Raineteau, O.
    • Journal Title

      PLoS One

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Dynamic expression of the pro-dopaminergic transcription factors Pax6 and Dlx2 during postnatal olfactory bulb neurogenesis2012

    • Author(s)
      de Chevigny, A., Core, N., Follert, P., Wild, S., Bosio, A., Yoshikawa, K., Cremer, H., Beclin, C.
    • Journal Title

      Front Cell Neurosci

      Volume: 6

    • DOI

      10.3389/fncel.2012.00006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Necdin controls Foxol acetylation in hypothalamic arcuate neurons to modulate the thyroid axis2012

    • Author(s)
      Hasegawa, K., Kawahara, T., Fujiwara, K., Shimpuku, M., Sasaki, T., Kitamura, T., Yoshikawa, K.
    • Journal Title

      Journal of Neuroscience

      Volume: 32 Pages: 5562-5572

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Necdin controls proliferation of white adipocyte progenitor cells2012

    • Author(s)
      Fujiwara K, Hasegawa K, Ohkumo T, Miyoshi H, Tseng Y-H, Yoshikawa K
    • Journal Title

      PLoS One

      Volume: 7(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Journal Article] ERK inhibition rescues defects in fate specification of Nf1 -deficient neural progenitors and brain abnormalities2012

    • Author(s)
      Wang, Y., Kim, E., Wang, X. Novitch, B. G., Yoshikawa, K., Chang, L. S., Zhu, Y.
    • Journal Title

      Cell

      Volume: 150 Issue: 4 Pages: 816-830

    • DOI

      10.1016/j.cell.2012.06.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Necdin controls proliferation of white adipocyte progenitor cells2012

    • Author(s)
      Fujiwara, K., Hasegawa, K., Ohkumo, T., Miyoshi, H., Tseng, Y. H., Yoshikawa, K.
    • Journal Title

      PLoS One

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Journal Article] Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus2011

    • Author(s)
      Aizawa T, Hasegawa K, Ohkumo T, Haga S, Ikeda K, Yoshikawa K
    • Journal Title

      Cancer Sci

      Volume: 102 Issue: 1 Pages: 122-129

    • DOI

      10.1111/j.1349-7006.2010.01775.x

    • NAID

      10029288727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Journal Article] Necdin promotes tangential migration of neocortical interneurons from basal forebrain2010

    • Author(s)
      Kuwajima T, Hasegawa K, Yoshikawa K
    • Journal Title

      J Neurosci

      Volume: 30 Issue: 10 Pages: 3709-3714

    • DOI

      10.1523/jneurosci.5797-09.2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Journal Article] Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons.2008

    • Author(s)
      Hasegawa K, Yoshikawa K
    • Journal Title

      Journal of Neuroscience 28

      Pages: 8772-8784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300122
  • [Journal Article] Drosophila MAGE controls neural precursor proliferation in postembryonic neurogenesis2008

    • Author(s)
      Nishimura l, Sakoda JY, Yoshikawa K
    • Journal Title

      Neuroscience 154

      Pages: 572-581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500323
  • [Journal Article] Drosophila MAGE controls neural precursor proliferation in postembryonic neurogenesis2008

    • Author(s)
      Nishimura I, Sakoda JY, Yoshikawa K
    • Journal Title

      Neuroscience 154

      Pages: 572-581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500323
  • [Journal Article] Drosophila MAGE controls neural precursor proliferation in postembryonic neurogenesis.2008

    • Author(s)
      Nishimura I, Sakoda JY, Yoshikawa K
    • Journal Title

      Neuroscience 154

      Pages: 572-581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300122
  • [Journal Article] Expression of Drosophila MAGE gene encoding a necdin homologous protein in postembryonic neurogenesis.2007

    • Author(s)
      Nishimura I, Shimizu S, Sakoda JY, Yoshikawa K
    • Journal Title

      Gene Expression Patterns 7

      Pages: 244-251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300122
  • [Journal Article] Necdin downregulates Cdc2 expression to attenuate neuronal apoptosis.2006

    • Author(s)
      Kurita M, Kuwajima T, Nishimura I, Yoshikawa K
    • Journal Title

      Journal of Neuroscience 26

      Pages: 12003-12013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300122
  • [Journal Article] Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins.2006

    • Author(s)
      Kuwajima T, Nishimura I, Yoshikawa K
    • Journal Title

      Journal of Neuroscience 26

      Pages: 5383-5392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300122
  • [Journal Article] 細胞増殖・分化・死のシグナル蛋白質Necdin/MAGEファミリー2004

    • Author(s)
      吉川和明
    • Journal Title

      蛋白質 核酸 酵素 49

      Pages: 2044-2051

    • NAID

      40006385536

    • Data Source
      KAKENHI-PROJECT-16300118
  • [Presentation] 神経前駆細胞におけるNecdinによる上皮成長因子受容体シグナルの制御機構2015

    • Author(s)
      藤本泉, 長谷川孝一, 藤原一志郎, 吉川和明
    • Organizer
      第88回 日本生化学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] Necdin promotes mitochondrial biogenesis to prevent neurodegeneration in experimental Parkinson's disease2015

    • Author(s)
      Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Mochizuki H, Yoshikawa K
    • Organizer
      Neuroscience 2015, Society for Neuroscience
    • Place of Presentation
      Chicago(USA)
    • Year and Date
      2015-10-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] ニューロン分化におけるNecdinによるRanGAP1のSUMO化制御2015

    • Author(s)
      藤原一志郎, 長谷川孝一, 吉川和明
    • Organizer
      第88回 日本生化学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] Promotion of neuronal mitochondiral biogenesis by necdin: Neuroprotection in experimental Parkinsonism2015

    • Author(s)
      吉川和明, 長谷川孝一, 安田徹, 望月秀樹
    • Organizer
      第38回 日本神経科学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] Necdin downregulates EGFR signaling in cortical neural precursor cells to suppress gliogenesis2015

    • Author(s)
      Fujimoto I, Hasegawa K, Fujiwara K, Yoshikawa K
    • Organizer
      Neuroscience 2015, ociety for Neuroscience
    • Place of Presentation
      Chicago(USA)
    • Year and Date
      2015-10-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] 哺乳類ニューロンのDNA修復におけるNecdinの関与2012

    • Author(s)
      瀬戸口良、長谷川孝一、三津昭博、吉川和明
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場(招待講演)
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] NecdinによるPGC-1αを介したニューロン内ミトコンドリア生合成の促進2012

    • Author(s)
      長谷川孝一、白石千夏、藤原一志郎、吉川和明
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場(招待講演)
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] In vitro SUMO化反応系によるNecdinのSUMO修飾解析2012

    • Author(s)
      藤原一志郎、長谷川孝一、江連徹、吉川和明
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場(招待講演)
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] 視床下部におけるnecdinは甲状腺ホルモンによるエネルギー消費を抑制する2011

    • Author(s)
      白石千夏、長谷川孝一、吉川和明
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      石川県加賀市
    • Year and Date
      2011-09-26
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] Necdinは哺乳類脳においSmc5/ 6構成要素と多蛋白質複合体を形成する2011

    • Author(s)
      柏木裕呂樹、長谷川孝一、吉川和明
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      石川県加賀市
    • Year and Date
      2011-09-26
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] Necdin regulates Fox01 acetylation via Sirt1 in mouse hypothalamus Society for Neuroscience2010

    • Author(s)
      Hasegawa K, Yoshikawa K
    • Organizer
      40th Annual Meeting
    • Place of Presentation
      San Diego USA
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] Necdin enhances Sirt1-dependent deacetylation of Fox01 to control hypothalamic thermoregulation2010

    • Author(s)
      長谷川孝一、川原知浩、吉川和明
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] Necdin serves as Nse3 in mammalian Smc5/ 6 complex2010

    • Author(s)
      吉田直史、長谷川孝一、吉川和明
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] Necdinによる上皮成長因子受容体シグナルの制御機構

    • Author(s)
      藤本泉、 長谷川孝一、 藤原一志郎、 吉川和明
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館 (京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] NecdinによるRanGAP1のSUMO化制御

    • Author(s)
      藤原一志郎、長谷川孝一、吉川和明
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜 (横浜市)
    • Year and Date
      2013-09-11 – 2013-09-13
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] Necdin suppresses PIAS1 SUMO E3 ligase activity by promoting ubiquitin-dependent degradation

    • Author(s)
      GUR Ibrahim、藤原一志郎、長谷川孝一、吉川和明
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜 (横浜市)
    • Year and Date
      2013-09-11 – 2013-09-13
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] NecdinとBmi1の拮抗的相互作用による神経幹細胞の増殖制御

    • Author(s)
      南出良平、長谷川孝一、藤原一志郎 吉川和明
    • Organizer
      第56回日本神経化学会大会
    • Place of Presentation
      国立京都国際会館 (京都市)
    • Year and Date
      2013-06-20 – 2013-06-23
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] Necdin regulates RanGAP1 sumoylation during neuronal differentiation

    • Author(s)
      Fujiwara, K., Hasegawa, K., Yoshikawa, K.
    • Organizer
      Neuroscience 2014
    • Place of Presentation
      Walter E. Washington Convention Center, Washington D.C.
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] NecdinによるPGC-1αの安定化を介したニューロン内ミトコンドリア生合成の促進

    • Author(s)
      長谷川孝一、白石千夏、藤原一志郎、吉川和明
    • Organizer
      第56回日本神経化学会大会
    • Place of Presentation
      国立京都国際会館 (京都市)
    • Year and Date
      2013-06-20 – 2013-06-23
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] NecdinによるPGC-1αを介したニューロン内ミトコンドリア機能の促進

    • Author(s)
      長谷川孝一、白石千夏、藤原 一志郎 吉川 和明
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜 (横浜市)
    • Year and Date
      2013-09-11 – 2013-09-13
    • Data Source
      KAKENHI-PROJECT-24300134
  • [Presentation] Necdinによるニューロン内ミトコンドリア機能の促進:パーキンソン病モデルにおける神経保護作用

    • Author(s)
      長谷川孝一、安田徹、白石千夏、藤原一志郎、望月秀樹、吉川和明
    • Organizer
      第57回日本神経化学会大会
    • Place of Presentation
      奈良県文化会館 (奈良市)
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PROJECT-24300134
  • 1.  UETSUKI Taichi (20260309)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  TANIURA Hideo (80263325)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  NISHIMURA Isao (70362621)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 4.  NIINOBE Michio (80135748)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  MIKI Naomasa (40094445)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  宮武 正 (50048998)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  榊 佳之 (10112327)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  OHKUMO Tsuyoshi (50432505)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 9.  HASEGAWA Koichi (20546783)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 30 results
  • 10.  KAMETANI Fuyuki (70186013)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  小野寺 一清 (90012773)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  竹田 俊男 (00027088)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  藤原 美定 (70030848)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  小幡 邦彦 (60013976)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  AIZAWA Takako
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  FUKUI Kenji (50165263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TSUCHIDA Hideto (40336748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MASAKI Daiki (00457970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  FUJIWARA Kazushiro (80638495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 20.  NAKAMURA Haruki (80134485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  MOCHIZUKI Hideki (90230044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 22.  MARUYAMA Kei (30211577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HAYASHI Yokichi (70173044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  OKADA Masato (10177058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  辻 省次 (70150612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  大木 操 (00158792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  田平 武 (80112332)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  小山 文隆 (40194641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  三木 哲郎 (00174003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  永井 克孝 (80072974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  栗山 欣弥 (20079734)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  遠山 正弥 (40028593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  芳賀 達也 (30011646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  山内 卓 (90041813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  津本 忠治 (50028619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  高城 啓一 (30250202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  杉浦 弘子 (40162870)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  矢尾板 芳郎 (00166472)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  USAMI Mihoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  YAMAMOTO Akihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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