Sasada Masataka 笹田昌孝

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SASADA Masataka 笹田昌孝

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Researcher Number	30144364
Other IDs
External Links
Affiliation (Current)	2025: 滋賀県立総合病院(臨床研究センター), その他部局等, 総長
Affiliation (based on the past Project Information) *help	2003 – 2006: 京都大学, 医学部, 教授 2000 – 2002: Kyoto University, College of Medical Technology, Professor, 医療技術短期大学部, 教授 1999: 京都大学, 医療技術短期大学, 教授 1997: 京都大学, 医療短期大学部・衛生技術学科, 教授 1995 – 1997: 京都大学, 医療短期大学部, 教授 … More 1996: 京都大学, 医療技術短期大学部, 教授 1991: 京都大学, 医療短期大学, 教授 1990: 京都大学, 医療短期大学部, 教授 1989: 京都大学, 医療技術短期大学部, 教授 1989: Prof., College of Med. Technol., 教授 1988: 京都大学, 医療短期大学部, 教授 1986: Faculty of medicine, Kyoto university , Assistant, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Hematology / 膠原病・アレルギー・感染症内科学 / Laboratory medicine Except Principal Investigator Hematology / Respiratory organ internal medicine / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 好中球 / neutrophils / transmigration / nitric oxide / 血管内皮 / トランスミグレーション / 遊走 / NO / 活性酸素 / chemotaxis … More / endothelial cell / guanylate cyclase / endothel / トランスミグラーション / グアニレートサイクラーゼ / 血管内皮細胞 / 感染症 / DDS / 抗菌薬 / FACS / 貪食殺菌能 / 骨髄 / 遊走因子 / 顆粒球機能 / 顆粒球 … More Except Principal Investigator アポトーシス / 骨髄異形成症候群 / 活性酸素 / thioredoxin / iNOS / peroxynitrite / propofol / geranylgeranylacetone / 6-formylpterin / apoptosis / 前白血病 / 血球分化 / エンドヌクレアーゼ / 無効造血 / サイトカイン / 造血幹細胞 / 血球の分化と増殖 / cellular dysfunction / ineffective hematopoiesis / MDS derived inhibition of CFU-gm / differentiation / cytokines / hematopoietic stem cells / preleukemia / MDS / 血球の分化異常と分化誘導 / 血球機能 / 分化誘導 / Protein kinase C / Respiratory burst / Oxygen radicals / Interferon-gamma / Candidacidal activity / Phagocytosis / Alveolar macrophages / 単球由来マクロファージ / C キナーゼ / 呼吸爆発 / インターフェロンガンマ / 殺カンジダ活性 / 貧食 / 肺胞マクロファージ / ROS / カスパーゼ / フローサイトメトリー / シクロヘキサミド / 抗Fas抗体 / 6FP / 活性酸素産生剤 / PBN / 活性酸素消去剤 / リポポリ多糖類 / 腫瘍壊死因子 / 肝細胞 / ラット / hematopoietic cell differentiation / human leukemia and preleukemia / endonuclease / 細胞増殖と細胞死 / 白血病 / 白血病・前白血病 / 分化 / HL-60細胞 / 血中濃度 / 活性vit【D_3】 / Ara-C少量療法 / Myelodisplastic symarome(MDS) / 非定型性白血病 / 急性白血病 / DNA切断化 / spoptosis / Hサブユニットフェリチン / 造血因子 / 単球の細胞傷害作用 / 血球の増殖 / インタ-ロイキン2受容体 / インタ-ロイキン2 Less

好中球を利用した抗菌薬を感染病巣に到達させる特異的DDSの開発Principal Investigator
- Principal Investigator
  
  笹田昌孝
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyoto University
Transmigration of neutrophils through epitheliumPrincipal Investigator
- Principal Investigator
  
  SASADA Masataka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Mechanism of transendothelial migration of neutrophilsPrincipal Investigator
- Principal Investigator
  
  SASADA Masataka
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Reactive oxygen species induced apoptosis in ischemia-reperfusion injury
- Principal Investigator
  
  ARAI Toshiyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  KYOTO UNIVERSITY
自動細胞解析装置を用いた多機能同時測定法の確立と好中球の機能的亜集団の解析Principal Investigator
- Principal Investigator
  
  笹田昌孝
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Apoptosis in Human leukemia and Preleukemia
- Principal Investigator
  
  YOSHIDA Yataro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
ヒト造血細胞のアポトーシスに関する基礎的並びに臨床的研究
- Principal Investigator
  
  吉田弥太郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
幹細胞生物学の立場からみた血球の分化と増殖に関する基礎的並びに臨床的研究
- Principal Investigator
  
  YOSHIDA Yataro
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
血球の増殖と機能分化におけるILー2とその受容体の役割
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
顆粒球の骨髄流出機構に関する研究Principal Investigator
- Principal Investigator
  
  笹田昌孝
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Institution
  Kyoto University
Pathobiology of the myelodysplastic syndromes
- Principal Investigator
  
  YOSHIDA Yataro, 内野治人
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
非定型性白血病の治療法の確立に関する基礎的臨床的研究
- Principal Investigator
  
  UCHINO Haruto
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Studies of human alveolar macrophages ( Functional aspects )
- Principal Investigator
  
  YAMAMOTO Kokichi
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University

All 2007 2006 2005 2004 2003

All Journal Article

[Journal Article] 感染症対策2007
- Author(s)
  笹田昌孝
- Journal Title
  
  日本臨床 65 (Suppl 1)
  
  Pages: 445-449
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] 顆粒球の生化学とエネルギー代謝2006
- Author(s)
  笹田昌孝
- Journal Title
  
  三輪血液病学 (第3版)
  
  Pages: 276-288
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] 適応疾患と治療 2) 重症感染症 (1)血液系2006
- Author(s)
  笹田昌孝
- Journal Title
  
  静注用免疫グロブリン製剤ハンドブック第1版
  
  Pages: 38-47
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] 顆粒球の機能2006
- Author(s)
  笹田昌孝
- Journal Title
  
  三輪血液病学 (第3版)
  
  Pages: 288-298
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] 薬剤と血液疾患2006
- Author(s)
  笹田昌孝
- Journal Title
  
  三輪血液病学 (第3版)
  
  Pages: 1855-1866
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] LPS-induced ROS generation and changes in glutathione level and their relation to the maturation of human monocyte-derived dendritic cells2006
- Author(s)
  Yamada H, Sasada M, et al.
- Journal Title
  
  Life Sci 78(9)
  
  Pages: 926-933
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] 薬剤による白血球機能障害2006
- Author(s)
  笹田昌孝, 伊藤洋志, 山下浩平
- Journal Title
  
  血液フロンティア 16(10)
  
  Pages: 1625-1630
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] Nitric oxide derived from human umbilical vein endothelial cells inhibits transendothelial migration of neutrophils.2005
- Author(s)
  Oka S, Sasada M, et al.
- Journal Title
  
  Int J Hematol (in press)
- NAID
  10015651500
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Nitric oxide derived from human umbilical vein endothelial cells inhibits transendothelial migration of neutrophils2005
- Author(s)
  Oka S, Sasada M, et al.
- Journal Title
  
  Int J Hematol 81(3)
  
  Pages: 220-227
- NAID
  10015651500
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] 感染症に伴う好中球機能亢進による病態形成2005
- Author(s)
  笹田昌孝
- Journal Title
  
  臨床血液 46(4)
  
  Pages: 240-244
- NAID
  10015549866
- Data Source
  KAKENHI-PROJECT-17659300
[Journal Article] Nitric oxide derived from human umbilical vein endothelial cells inhibits transendothelial migration of neutrophils2005
- Author(s)
  Oka S, Sasada M, et al.
- Journal Title
  
  J Hematol 81(3)
  
  Pages: 220-227
- NAID
  10015651500
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Nitric oxide derived from human umbilical vein endothelial cells inhibits transendothelial migration of neutrophils.2005
- Author(s)
  Oka S, Sasada M, et al.
- Journal Title
  
  Int J Hematol 81(3)
  
  Pages: 220-227
- NAID
  10015651500
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] E148Q/M694I mutation in 3 Japanese patients with familial Mediterranean fever.2004
- Author(s)
  Kotone-Miyahara Y, Sasada M, et al.
- Journal Title
  
  Int J Hematol 79(3)
  
  Pages: 235-237
- NAID
  10012923838
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] E148Q/M694I mutation in 3 Japanese patients with familial Mediterranean fever2004
- Author(s)
  Kotone-Miyahara Y, Takaori-Kondo A, Fukunaga K, Goto M, Hayashino Y, Miki, Takayama H, Sasada M, Uchiyama T
- Journal Title
  
  Int J Hematol 79(3)
  
  Pages: 235-237
- NAID
  10012923838
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Granulocyte/macrophage colony-stimulating factor inhibits Fas-stimulated neutrophil apoptosis by suppressing FADD recruitment : evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase C.2004
- Author(s)
  Kotone-Miyahara Y, Sasada M, et al.
- Journal Title
  
  J Leukoc Biol 76(5)
  
  Pages: 1047-1056
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Granulocyte/macrophage colony-stimulating factor inhibits Fas-stimulated neutrophil apoptosis by suppressing FADD recruitment : evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase C2004
- Author(s)
  Kotone-Miyahara Y, Yamashita K, Lee KK, Yonehara S, Uchiyama T, Sasada M, Takahashi A
- Journal Title
  
  J Leukoc Biol 76(5)
  
  Pages: 1047-1056
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Effects of intracellular reactive oxygen species generated by 6-formylpterin on T cell functions.2004
- Author(s)
  Arai T, Sasada M, et al.
- Journal Title
  
  Biochem Pharmacol 67(6)
  
  Pages: 1185-1193
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Effects of 6-formylpterin as an internal source of hydrogen peroxide on cell death of human peripheral blood leukocytes2003
- Author(s)
  Nishioka M, Arai T, Yamashita K, Sasada M, Mori H, Ishii H, Tajima K, Makino K, Fukuda K
- Journal Title
  
  Life Science 73(2)
  
  Pages: 221-231
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] 白血球機能異常症2003
- Author(s)
  笹田昌孝
- Journal Title
  
  ダイナミック・メディシン 3
  
  Pages: 123-125
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Diseases of leukocyte dysfunctions2003
- Author(s)
  Sasada M
- Journal Title
  
  Dynamic Medicine 3
  
  Pages: 123-125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] 好中球と病態形成-好中球の二面性-2003
- Author(s)
  笹田昌孝
- Journal Title
  
  臨床血液 44(6)
  
  Pages: 351-357
- NAID
  10011470093
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Effects of 6-formylpterin as an internal source of hydrogen peroxide on cell death of human peripheral blood leukocytes2003
- Author(s)
  Nishioka M, Sasada M, et al.
- Journal Title
  
  Life Science 73(2)
  
  Pages: 221-231
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591003
[Journal Article] Pathophysiologic formation by neutrophils : dual aspects of neutrophils (in Japanese)2003
- Author(s)
  Sasada M
- Journal Title
  
  Clinical Hematology 44(6)
  
  Pages: 351-357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591003

1. YOSHIDA Yataro (80064525)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. OGUMA Shigeru (00169260)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. UCHINO Haruto (40034615)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. YAMAGISHI Morihisa (50026829)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ITOH Kazuhiko (50034640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YAMAMOTO Kokichi (10166796)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ARAI Toshiyuki (80175950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUZE Fumiyuki (10027104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 内山卓 (80151900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 藤井信孝 (60109014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 伊藤洋志 (20362387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 田嶌政郎 (10171688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 澤田博義 (30093248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sasada Masataka 笹田 昌孝

SASADA Masataka 笹田 昌孝

Research Projects

Research Products

Co-Researchers

好中球を利用した抗菌薬を感染病巣に到達させる特異的DDSの開発Principal Investigator

Principal Investigator

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Transmigration of neutrophils through epitheliumPrincipal Investigator

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Mechanism of transendothelial migration of neutrophilsPrincipal Investigator

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Principal Investigator

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自動細胞解析装置を用いた多機能同時測定法の確立と好中球の機能的亜集団の解析Principal Investigator

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Principal Investigator

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Principal Investigator

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顆粒球の骨髄流出機構に関する研究Principal Investigator

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[Journal Article] 感染症対策2007

Author(s)

Journal Title

Data Source

[Journal Article] 顆粒球の生化学とエネルギー代謝2006

Author(s)

Journal Title

Sasada Masataka 笹田昌孝

SASADA Masataka 笹田昌孝