INOKOSHI Junji 猪腰淳嗣

Researcher Number	30151640
Other IDs
Affiliation (Current)	2021: 北里大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2011 – 2013: 北里大学, 薬学部, 准教授 2007 – 2008: 北里大学, 薬学部, 准教授 2005 – 2006: 北里大学, 薬学部, 助教授 2000 – 2003: 北里大学, 薬学部, 講師 1997: Kitasato University, School of Pharmaceutical Sciences, Associate Professor, 薬学部, 講師 1995 – 1996: 北里大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Chemical biology Except Principal Investigator Biological Sciences / Science and Engineering / Chemical pharmacy / Living organism molecular science / Biological pharmacy
Keywords	Principal Investigator actinohivin / 抗HIV / 組換え蛋白質 / 合胞体形成 / 生産 / 放線菌 / 大腸菌 / 阻害剤 / Actinohivin / anti-HIV … More Except Principal Investigator 脂質代謝 / 阻害剤 / 感染症 / 医療・福祉 / ケミカルバイオロジー / 抗HIV / タンパク質 / actinohivin / 合胞体形成 / high mannose type / クローニング / 組換え細胞 / 侵入 / 微生物由来機能分子 / コレステロール / 中性脂肪 / トリグリセリド / 循環器・高血圧 / 医療福祉 / 動脈硬化症 / ACAT アイソザイム / ACATアイソザイム / 天然物 / 標的分子 / 結合タンパク質 / ケミカルバイォロジー / ミリストイル化 / ファルネシル化 / HIV Gag蛋白質 / トリアクシン / アシルCoA合成酵素 / Ras蛋白質 / アンドラスチン / 抗エイズ薬 / 抗癌剤 / 脂質修飾蛋白質 / アシル化 / 抗エイズ剤 / Myristoylation / Farnesyltransferase / HIV Gag protein / Triacsin / Acly-Coa synthetase / Inhibitor / Ras protein / Andrastin Less

Structure-activity relationship of lariatinPrincipal Investigator
- Principal Investigator
  
  INOKOSHI Junji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Kitasato University
THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTS
- Principal Investigator
  
  TOMODA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kitasato University
Discovery and development of selectivity-defined inhibitors toward two acyl-CoA : cholesterol acyltransferase isozymes
- Principal Investigator
  
  TOMODA Hiroshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
脂質代謝を制御する機能分子プローブの創製
- Principal Investigator
  
  TOMODA Hiroshi
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kitasato University
Analysis of essential regions for biological activities of the potent anti-HIV protein actinohivin that binds to high-mannose sugar chains of gp 120Principal Investigator
- Principal Investigator
  
  INOKOSHI Junji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
新しいHIV接着・侵入阻害剤の作用機構と創薬基礎研究
- Principal Investigator
  
  田中晴雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
Recombinant production of the anti-HIV protein actinohivin of actinomycete origin in Escherichia coli and analysis of essential region of actinohivin using its mutantsPrincipal Investigator
- Principal Investigator
  
  INOKOSHI Junji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Studies on the cellular functions of lipid-modified proteins
- Principal Investigator
  
  OHMURA Satoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Kitasato Institute

All 2012 2011 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B01712012
- Author(s)
  Inokoshi J, Matsuhama M, Miyake M, Ikeda H, Tomoda H
- Journal Title
  
  Appl. Microbiol. Biotechnol 2012
  
  Volume: 95 Pages: 451-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510282
[Journal Article] Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B01712012
- Author(s)
  Inokoshi J, Matsuhama M, Miyake M, Ikeda H, Tomoda H.
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: (In press) Pages: 451-460
- DOI
  10.1007/s00253-012-3973-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310146, KAKENHI-PLANNED-22108006
[Journal Article] Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171.2012
- Author(s)
  Inokoshi J, Matsuhama M, Miyake M, Ikeda H, Tomoda H.
- Journal Title
  
  Appl Microbiol Biotechnol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510282
[Journal Article] Expression of two human acyl-CoA : diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes.2009
- Author(s)
  J. Inokoshi, et al.
- Journal Title
  
  J. Antibiot. 62
  
  Pages: 51-54
- NAID
  10030634523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390008
[Journal Article] Expression of two human acyl-CoA : diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes2009
- Author(s)
  Inokoshi J, Kawamoto K, Takagi Y, Matsuhama M, Omura S, Tomoda H.
- Journal Title
  
  J. Antibiot 62
  
  Pages: 51-54
- NAID
  10030634523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390008
[Patent] 新規FKI・3368物質およびその製造方法2007
- Inventor(s)
  供田洋, 猪腰淳嗣, 増間縁郎, 大村智
- Industrial Property Rights Holder
  北里学園
- Filing Date
  2007-09-14
- Data Source
  KAKENHI-PROJECT-16073215
[Presentation] 真菌FKI-4533株が生産するウンデカプレニル2リン酸合成酵素阻害物質に関する研究2012
- Author(s)
  猪腰淳嗣, ら
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21310146
[Presentation] Analysis of essential amino acids in lasso peptide lariatins for anti-mycobacterial activity by single amino acid substitution2012
- Author(s)
  Inokoshi J, et al
- Organizer
  The 6th Korea-Japan Chemical Biology Symposium
- Place of Presentation
  Sapporo
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-21310146
[Presentation] Analysis of essential amino acids in lasso peptide lariatins for anti-mycobacterial activity by single amino acid substitution2012
- Author(s)
  J. Inokoshi, M. Miyake, Y. Shimizu, H. Tomoda
- Organizer
  The 6th Korea-Japan Chemical Biology Symposium
- Place of Presentation
  札幌
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-23510282
[Presentation] 抗結核活性を示す放線菌由来投げ縄ペプチド・lariatinの生合成機構の解析とアミノ酸置換変異体の構造活性相関2012
- Author(s)
  猪腰淳嗣 ,供田洋
- Organizer
  天然薬物の開発と応用シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2012-11-01
- Data Source
  KAKENHI-PROJECT-23510282
[Presentation] 投げ縄構造を有するペプチドlariatinの生合成に関する研究-LarCの構造解析-2011
- Author(s)
  猪腰淳嗣, ら
- Organizer
  第14回北里微生物アカデミー研究集会
- Place of Presentation
  相模原
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-21310146
[Presentation] Cloning and characterization of the lariatin biosynthetic gene cluster from Rhodococcus jostii K01-B0171.2009
- Author(s)
  Inokoshi J
- Organizer
  3th Asia-Pacific International Peptide Symposium
- Place of Presentation
  Jeju, Korea
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-21310146
[Presentation] 天然由来DGAT阻害剤のアイソザイム選択性2008
- Author(s)
  猪腰淳嗣, 他
- Organizer
  第50回目本薬脂質生化学会
- Place of Presentation
  徳島
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-18390008
[Presentation] 真菌FO-2942 株の生産する新しいamidepsine 成分に関する研究2008
- Author(s)
  高木陽一, 猪腰淳嗣, 内田龍児, 増間碌郎, 大村智, 供田洋
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18390008
[Presentation] 抗結核活性を示す放線菌由来投げ縄ペプチド・lariatin の生合成機構の解析とアミノ酸置換変異体の構造活性相関
- Author(s)
  猪腰淳嗣, 供田洋
- Organizer
  天然薬物の開発と応用シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23510282

1. TOMODA Hiroshi (70164043)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. CHIBA Harumi (90276163)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NAGAMITSU Tohru (90300756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KOYAMA Nobuhiro (60439156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ISHIBASHI Shun (90212919)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SUNAZUKA Toshiaki (30226592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UCHIDA Ryuji (60280632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UMEYAMA Hideaki (20050619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OHMURA Satoshi (90050426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ARAI Hiroyuki (40167987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MASUMA Rokuro (90219353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MORIKAWA Yuko (20191017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田中晴雄 (40118823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

INOKOSHI Junji 猪腰 淳嗣

Research Projects

Research Products

Co-Researchers

Structure-activity relationship of lariatinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discovery and development of selectivity-defined inhibitors toward two acyl-CoA : cholesterol acyltransferase isozymes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脂質代謝を制御する機能分子プローブの創製

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of essential regions for biological activities of the potent anti-HIV protein actinohivin that binds to high-mannose sugar chains of gp 120Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しいHIV接着・侵入阻害剤の作用機構と創薬基礎研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Recombinant production of the anti-HIV protein actinohivin of actinomycete origin in Escherichia coli and analysis of essential region of actinohivin using its mutantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the cellular functions of lipid-modified proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B01712012

Author(s)

Journal Title

Data Source

[Journal Article] Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B01712012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171.2012

Author(s)

Journal Title

Data Source

[Journal Article] Expression of two human acyl-CoA : diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Expression of two human acyl-CoA : diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes2009

Author(s)

Journal Title

NAID

Data Source

[Patent] 新規FKI・3368物質およびその製造方法2007

Inventor(s)

Industrial Property Rights Holder

Filing Date

Data Source

INOKOSHI Junji 猪腰淳嗣