Shimoda Shinji 下田慎治

… Alternative Names

下田慎治シモダシンジ

SHIMODA Shinji 下田慎治

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Researcher Number	30279319
Other IDs
External Links
Affiliation (Current)	2025: 関西医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 関西医科大学, 医学部, 教授 2016 – 2019: 九州大学, 大学病院, 准教授 2014 – 2016: 九州大学, 大学病院, 講師 2012: 九州大学, 大学病院, 講師 2010 – 2011: 九州大学, 医学研究院, 助教 … More 2008: Kyushu University, 大学院・医学研究科, 助教 2008: Kyushu University, 大学院・医学研究院, 助教 2007: Kyushu University, 大学医学研究院, 助教 2006: Kyushu University, Medicine and Biosystemic Science, Research Associate, 大学院医学研究院, 助手 2005: 九州大学, 医学研究院, 助手 2003 – 2005: 九州大学, 大学院・病態修復内科学, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Digestive surgery / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 原発性胆汁性肝硬変 / 原発性胆汁性胆管炎 / NK細胞 / 胆管上皮細胞 / 疾患模倣培養系 / 胆管細胞 / PBC / ケモカイン / 免疫学 / 単一細胞解析 … More / オミックス解析 / 病態模倣培養系 / 脂質メディエーター / GWA / 網羅的資質解析 / 網羅的遺伝子解析 / ゲノムワイド関連解析 / 脂質情報 / 網羅的アレイ解析 / 免疫細胞 / chemokine / target cells / antigen presenting cells / toll-like receptor / biliary epithelial cells / primary biliary cirrhosis / 胆管上皮細胞株 / T細胞クローン / 標的細胞 / 抗原提示細胞 / Toll-like receptor / インフラマソーム / IL-1b / NLRP3 / 悪性サイクル / 細胞老化 / IFN-g / 疎水性胆汁酸 / anion exchanger 2 / IFN-a / 単球 / TLR4リガンド / TLR3リガンド / 肝臓浸潤単核球 / 胆管破壊 / モデルマウス / 自然免疫 / 原発生胆汁性肝硬変 / 細胞傷害活性 / TLRリガンド / 肝臓 / 臨床 / 細胞組織 … More Except Principal Investigator 肝線維化 / 原発性胆汁性肝硬変 / 分子標的 / 疾患発症経路 / 疾患感受性遺伝子 / ゲノムワイド関連解析 / 原発性胆汁性胆管炎 / 免疫チェックポイント阻害剤 / 細胞老化 / 網羅的遺伝子発現解析 / 統合解析 / トランスクリプトーム / 分離培養 / 肝実質細胞 / Galactin 3 / バイオマーカー / 糖鎖 / T細胞 / 糖蛋白 / 肝星細胞 / マクロファージ / galectin 3 / WFA-M2BP / 脾硬度 / EndMt / 脾腫 / 肝内微小循環障害 / EndMT / 類洞内皮細胞 / 脾機能亢進症 / 門脈圧亢進症 / 脾門脈外科 / anti-mitochondrial antibody / prediction of prognosis / anti-gp210 antibody / Toll-like receptor (TLR) / innate immunity / biliary epithelial cells / bile duct damage / primary biliary cirrhosis / 病因関連抗原 / CD8陽性T細胞 / 自己反応性T細胞 / ミトコンドリア抗体 / 予後予測因子 / 抗原特異的T細胞 / ミトコンドリア抗原 / PPARα / 予後予測マーカー / 抗ミトコンドリア抗体 / 抗gp210抗体 / Toll-like受容体 / 自然免疫 / 胆管上皮細胞 / 胆管障害 / GWAS / 肝臓学 / 病型分類 / 予後予測 Less

細胞老化の蓄積解除から切り開く新規肝疾患治療法の基盤開発
- Principal Investigator
  
  山口隆志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kansai Medical University
Establishment of novel therapeutic strategies for primary biliary cholangitis by integrating omics and single cell analysis informationPrincipal Investigator
- Principal Investigator
  
  下田慎治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kansai Medical University
Development of new treatment methods for primary biliary cholangitis by genome and lipid information from disease mimic culture systemPrincipal Investigator
- Principal Investigator
  
  Shimoda Shinji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
GWAS-based integrated analysis of PBC to dissect the mechanism of development and progression of primary biliary cholangitis
- Principal Investigator
  
  Nakamura Minoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
Multidisciplinary treatment focusing on impaired intrahepatic microcirculation and splenic dysfunction in liver cirrhosis and portal hypertension
- Principal Investigator
  
  Kawanaka Hirofumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  National Hospital Organization, Beppu Medical Center
The biological analysis of sugar chain signal between hepatic stelate cells and macrophages in the progression of liver fibrosis.
- Principal Investigator
  
  Shirabe Ken
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
  Kyushu University
Analysis of disease-pathways and molecular targets by disease-susceptibility genes in primary biliary cholangitis
- Principal Investigator
  
  Nakamura Minoru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
Clarification of the pathogenecity and the application of therapies from biliary epithelial cells in primary biliary cholangitisPrincipal Investigator
- Principal Investigator
  
  Shimoda Shinji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
The mechanism of bile duct destruction in Primary Biliary CirrhosisPrincipal Investigator
- Principal Investigator
  
  SHIMODA Shinji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Innate and acquired immunity for primary biliary cirrhosisPrincipal Investigator
- Principal Investigator
  
  SHIMODA Shinji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
The roles for biliary epithelial cells as antigen presenting cells or target cells in primary biliary cirrhosisPrincipal Investigator
- Principal Investigator
  
  SHIMODA Shinji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KYUSHU UNIVERCIT
Dissection of autoimmune response and establishment of diagnosis and treatment of primary biliary cirrhosis
- Principal Investigator
  
  ISHIBASHI Hiromi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Clinical Research Center National Hospital Organization (NHO) Nagasaki Medical Center

[Book] 肝臓病の最新治療(戸田剛太郎,沖田極,門田守人,井廻道夫,幕内雅敏,恩地森一,森正樹,茶山一彰,持田智,銭谷幹男編集)2006
- Author(s)
  石橋大海, 下田慎治, 中村稔
- Total Pages
  406
- Publisher
  先端医療技術研究所
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Book] The Pathophysiology of the Biliary Epithelia,2004
- Author(s)
  Shinji Shimoda, Akiyoshi Nishio, Hiromi Ishibashi,, M.Eric Gershwin
- Total Pages
  454
- Publisher
  LANDES BIOSCIENCE, GEORGETOWN, EUREKAH. COM, AUSTIN
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Cost-effectiveness analysis of sofosbuvir plus ribavirin in patients with genotype 2 chronic hepatitis C: an analysis with real world outcomes from a multicentre cohort in Japan.2019
- Author(s)
  Igarashi A, et al, Shimoda S, et al.
- Journal Title
  
  BMJ Open.
  
  Volume: 9
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Pruritus in Chronic Liver Disease: A Questionnaire Survey on 216 Patients.2019
- Author(s)
  Kido-Nakahara M, et al, Shimoda S, et al.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: 99
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33.2019
- Author(s)
  Hitomi Y, et al, Shimoda S,et al.
- Journal Title
  
  Sci Rep.
  
  Volume: 9
- NAID
  120007179055
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Glecaprevir and Pibrentasvir for Japanese patients with chronic hepatitis C genotype 1 or 2 infection: Results from a multicenter, real-world cohort study.2019
- Author(s)
  Ogawa E, et al, Shimoda S, et al.
- Journal Title
  
  Hepatol Res.
  
  Volume: 49
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Nishida N, Aiba Y, Hitomi Y, Kawashima M, Kojima K, Kawai Y, Ueno K, Nakamura H, Yamashiki N, Tanaka T, Tamura S, Mori A, Yagi S, Soejima Y, Yoshizumi T, Takatsuki M, Tanaka A, Harada K, Shimoda S, Komori A, Eguchi S, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M2018
- Author(s)
  Nishida N, Aiba Y, Hitomi Y, Kawashima M, Kojima K, Kawai Y, Ueno K, Nakamura H, Yamashiki N, Tanaka T, Tamura S, Mori A, Yagi S, Soejima Y, Yoshizumi T, Takatsuki M, Tanaka A, Harada K, Shimoda S, Komori A, Eguchi S, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M
- Journal Title
  
  Sci Rep.
  
  Volume: 8(1) Pages: 8071-8071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis2018
- Author(s)
  Aiba Yoshihiro、Harada Kenichi、Ito Masahiro、Suematsu Takashi、Aishima Shinichi、Hitomi Yuki、Nishida Nao、Kawashima Minae、Takatsuki Mitsuhisa、Eguchi Susumu、Shimoda Shinji、Nakamura Hitomi、Komori Atsumasa、Abiru Seigo、Nagaoka Shinya、Migita Kiyoshi、Yatsuhashi Hiroshi、Tokunaga Katsushi、Nakamura Minoru
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 11808-11808
- DOI
  10.1038/s41598-018-30146-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09449, KAKENHI-PROJECT-17K15924, KAKENHI-PROJECT-17H04169
[Journal Article] Kawano A, Shigematsu H, Miki K, Ichiki Y, Morita C, Yanagita K, Takahashi K, Dohmen K, Nomura H, Ishibashi H, Shimoda S.2018
- Author(s)
  Kawano A, Shigematsu H, Miki K, Ichiki Y, Morita C, Yanagita K, Takahashi K, Dohmen K, Nomura H, Ishibashi H, Shimoda S.
- Journal Title
  
  Intern Med.
  
  Volume: 57(11) Pages: 1533-1542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Short-term risk of hepatocellular carcinoma after hepatitis C virus eradication following direct-acting anti-viral treatment.2018
- Author(s)
  Ogawa E, Furusyo N, Nomura H, Dohmen K, Higashi N, Takahashi K, Kawano A, Azuma K, Satoh T, Nakamuta M, Koyanagi T, Kato M, Shimoda S, Kajiwara E, Hayashi J; Kyushu University Liver Disease Study (KULDS) Group
- Journal Title
  
  Aliment Pharmacol Ther.
  
  Volume: 47(1) Pages: 104-113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Elbasvir plus grazoprevir for patients with chronic hepatitis C genotype 1: A multicenter, real-world cohort study focusing on chronic kidney disease2018
- Author(s)
  Ogawa E, Furusyo N, Azuma K, Nakamuta M, Nomura H, Dohmen K, Satoh T, Kawano A, Koyanagi T, Ooho A, Takahashi K, Kato M, Shimoda S, Kajiwara E, Hayashi J; Kyushu University Liver Disease Study (KULDS) Group
- Journal Title
  
  Antiviral Res.
  
  Volume: 159 Pages: 143-152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis2018
- Author(s)
  Aiba Y, Harada K, Ito M, Suematsu T, Aishima S, Hitomi Y, Nishida N, Kawashima M, Takatsuki M, Eguchi S, Shimoda S, Nakamura H, Komori A, Abiru S, Nagaoka S, Migita K, Yatsuhashi H, Tokunaga K, Nakamura M
- Journal Title
  
  Sci Rep
  
  Volume: 8(1) Pages: 11808-11808
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Hepatic stellate cells secreting WFA+ -M2BP: Its role in biological interactions with Kupffer cells.2017
- Author(s)
  Bekki Y, Yoshizumi T, Shimoda S, Itoh S, Harimoto N, Ikegami T, Kuno A, Narimatsu H, Shirabe K, Maehara Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 32 Pages: 1387-1393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.2017
- Author(s)
  Kawashima M, et al, Shimoda S, et al, Nakamura M.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 26 Pages: 650-659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04164
[Journal Article] Hepatic stellate cells secrete WFA+ -M2BP; its role in biological interactions with Kupffer cells.2017
- Author(s)
  Bekki Y,, Yoshizumi T, Shimoda S, Itoh S, Harimoto N, Ikegami T, Kuno A, Narimatsu H, Shirabe K, Maehara Y.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 32 Issue: 7 Pages: 1387-1393
- DOI
  10.1111/jgh.13708
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04932, KAKENHI-PROJECT-15K10167
[Journal Article] Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis2016
- Author(s)
  Hisamoto S, Shimoda S, Harada K, et al
- Journal Title
  
  J Autoimmun
  
  Volume: 75 Pages: 150-160
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis.2016
- Author(s)
  Hisamoto S, Shimoda S, Harada K, Iwasaka S, Onohara S, Chong Y, Nakamura M, Bekki Y, Yoshizumi T, Ikegami T, Maehara Y, He XS, Gershwin ME, Akashi K.
- Journal Title
  
  J Autoimmun.
  
  Volume: 75 Pages: 150-160
- DOI
  10.1016/j.jaut.2016.08.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26460416
[Journal Article] Natural killer cells regulate T cell immune responses in primary biliary cirrhosis.2015
- Author(s)
  Shimoda S, Hisamoto S, Harada K, Iwasaka S, Chong Y, Nakamura M, Bekki Y, Yoshizumi T, Shirabe K, Ikegami T, Maehara Y, He XS, Gershwin ME, Akashi K.
- Journal Title
  
  Hepatology.
  
  Volume: 62 Issue: 6 Pages: 1817-1827
- DOI
  10.1002/hep.28122
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10167, KAKENHI-PROJECT-26460416, KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-26293181
[Journal Article] Effectiveness of triple therapy with simeprevir for chronic hepatitis C genotype 1b patients with prior telaprevir failure.2015
- Author(s)
  Ogawa E, Furusyo N, Dohmen K, Kajiwara E, Kawano A, Nomura H, Takahashi K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J; Kyushu University Liver Disease Study (KULDS) Group.
- Journal Title
  
  J Viral Hepat.
  
  Volume: 22 Pages: 992-1001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Risk Factors Associated with Stenotrophomonas maltophilia Bacteremia: A Matched Case-Control Study.2015
- Author(s)
  Sumida K, Chong Y, Miyake N, Akahoshi T, Yasuda M, Shimono N, Shimoda S, Maehara Y, Akashi K.
- Journal Title
  
  PLoS One.
  
  Volume: 24 Pages: 1-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Comparative safety study on severe anemia by simeprevir- versus telaprevir-based triple therapy for chronic hepatitis C.2015
- Author(s)
  Ogawa E, Furusyo N, Kajiwara E, Nomura H, Kawano A, Takahashi K, Dohmen K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 30 Pages: 1309-1316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Natural killer cells regulate T cell immune responses in primary biliary cirrhosis.2015
- Author(s)
  Shimoda S, Hisamoto S, Harada K, Iwasaka S, Chong Y, Nakamura M, Bekki Y, Yoshizumi T, Shirabe K, Ikegami T, Maehara Y, He XS, Gershwin ME, Akashi K.
- Journal Title
  
  Hepatology
  
  Volume: 62 Pages: 1817-1827
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Bacterial Infection as an Adverse Effect of Telaprevir-based Triple Therapy for Chronic Hepatitis C Infection.2015
- Author(s)
  Kawano A, Ogawa E, Furusyo N, Nakamuta M, Kajiwara E, Dohmen K, Nomura H, Takahashi K, Satoh T, Azuma K, Tanabe Y, Shimoda S, Kotoh K, Hayashi J; Kyushu University Liver Disease Study (KULDS) Group.
- Journal Title
  
  Intern Med.
  
  Volume: 54 Pages: 567-572
- NAID
  130004903089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Comparative effectiveness and safety study of triple therapy with simeprevir or telaprevir for non-cirrhotic patients with chronic hepatitis C virus genotype 1b infection.2015
- Author(s)
  Ogawa E, Furusyo N, Kajiwara E, Nomura H, Kawano A, Takahashi K, Dohmen K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 30 Pages: 1759-1767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Importance of virological response in the early stage of telaprevir-based triple therapy for hepatitis C.2015
- Author(s)
  Hiramine S, Furusyo N, Ogawa E, Nakamuta M, Kajiwara E, Nomura H, Dohmen K, Takahashi K, Satoh T, Azuma K, Kawano A, Koyanagi T, Kotoh K, Shimoda S, Hayashi J.
- Journal Title
  
  World J Hepatol.
  
  Volume: 18 Pages: 2688-2695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] A dramatic increase in the positive blood culture rates of Helicobacter cinaedi: the evidence of differential detection abilities between the Bactec and BacT/Alert systems.2015
- Author(s)
  Miyake N, Chong Y, Nishida R, Nagasaki Y, Kibe Y, Kiyosuke M, Shimomura T, Shimono N, Shimoda S, Akashi K.
- Journal Title
  
  Diagn Microbiol Infect Dis.
  
  Volume: 83 Pages: 232-233
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Risk factors for hepatitis B virus recurrence after living donor liver transplantation: A 17-year experience at a single center.2015
- Author(s)
  Bae SK, Shimoda S, Ikegami T, Yoshizumi T, Harimoto N, Itoh S, Soejima Y, Uchiyama H, Shirabe K, Maehara Y.
- Journal Title
  
  Hepatol Res.
  
  Volume: 45 Pages: 1203-1210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Decreased secretion of Paneth cell α-defensins in graft-versus-host disease.2015
- Author(s)
  Eriguchi Y, Nakamura K, Hashimoto D, Shimoda S, Shimono N, Akashi K, Ayabe T, Teshima T.
- Journal Title
  
  Transpl Infect Dis.
  
  Volume: 17 Pages: 702-706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461012
[Journal Article] Alteration of energy metabolism in the pathogenesis of bile duct lesions in primary biliary cirrhosis.2014
- Author(s)
  Harada K, Kakuda Y, Sato Y, Ikeda H, Shimoda S, Yamamoto Y, Inoue H, Ohta H, Kasashima S, Kawashima A, Nakanuma Y.
- Journal Title
  
  J Clin Pathol
  
  Volume: 67(5) Issue: 5 Pages: 396-402
- DOI
  10.1136/jclinpath-2013-201815
- NAID
  120005469783
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590375, KAKENHI-PUBLICLY-25126709, KAKENHI-PROJECT-26282022, KAKENHI-PROJECT-26460416, KAKENHI-PROJECT-26461012, KAKENHI-PROJECT-26670599
[Journal Article] Systemic and local expression levels of TNF-like ligand 1A and its decoy receptor 3 are increased in primary biliary cirrhosis.2013
- Author(s)
  Aiba Y, Harada K, Komori A, Ito M, Shimoda S, Nakamura H, Nagaoka S, Abiru S, Migita K, Ishibashi H, Nakanuma Y, Nishida N, Kawashima M, Tokunaga K, Yatsuhashi H, Nakamura M.
- Journal Title
  
  Liver Int.
  
  Volume: 34 Issue: 5 Pages: 679-688
- DOI
  10.1111/liv.12296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590393, KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-25860576, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26461012
[Journal Article] Vigorous cleaning and adequate ventilation are necessary to control an outbreak in a neonatal intensive care unit2012
- Author(s)
  Shimono N, Hayashi J, Matsumoto H, Miyake N, Uchida Y, Shimoda S, Furusyo N, Akashi K
- Journal Title
  
  J Infect Chemother
  
  Volume: 18(3) Pages: 303-7
- NAID
  10030787099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Fractalkine and other chemokines in primary biliary cirrhosis.2012
- Author(s)
  Shimoda Shinji
- Journal Title
  
  Int J Hepatol.
  
  Volume: 102839 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis.2012
- Author(s)
  Shimoda Shinji
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: Jun;168(3) Pages: 279-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Modulation of CD4^+ T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis2011
- Author(s)
  Hashimoto N, Shimoda S, Kawanaka H, Tsuneyama K, Uehara H, Akahoshi T, Kinjo N, Taketomi A, Shirabe K, Akashi K, Lleo A, Ansari AA, Gershwin ME, Maehara Y
- Journal Title
  
  Clin Exp Immunol
  
  Volume: Aug;165(2) Pages: 243-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis2011
- Author(s)
  Tsuda M, Ambrosini YM, Zhang W, Yang GX, Ando Y, Rong G, Tsuneyama K, Sumida K, Shimoda S, Bowlus CL, Leung PS, He XS, Coppel RL, Ansari AA, Lian ZX, Gershwin ME
- Journal Title
  
  Hepatology
  
  Volume: 54(4) Pages: 1293-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Epigenetic investigation of variably X chromosome inactivated genes in monozygotic female twins discordant for primary biliary cirrhosis2011
- Author(s)
  Mitchell MM, Lleo A, Zammataro L, Mayo MJ, Invernizzi P, Bach N, Shimoda S, Gordon S, Podda M, Gershwin ME, Selmi C, LaSalle JM
- Journal Title
  
  Epigenetics
  
  Volume: 6(1) Pages: 95-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Significance of periductal Langerhans cells and biliary epithelial cell-derived macrophage inflammatory protein-3α in the pathogenesis of primary biliary cirrhosis2011
- Author(s)
  Harada K, Shimoda S, Ikeda H, Chiba M, Hsu M, Sato Y, Kobayashi M, Ren XS, Ohta H, Kasashima S, Kawashima A, Nakanuma Y
- Journal Title
  
  Liver Int
  
  Volume: Feb;31(2) Pages: 245-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis2011
- Author(s)
  Shimoda S, Harada K, Niiro H, Shirabe K, Taketomi A, Maehara Y, Tsuneyama K, Nakanuma Y, Leung P, Ansari AA, Gershwin ME, Akashi K
- Journal Title
  
  Hepatology
  
  Volume: 53(4) Pages: 1270-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Modulation of CD4 T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis2011
- Author(s)
  Hashimoto N, Shimoda S, Kawanaka H, Tsuneyama K, Uehara H, Akahoshi T, Kinjo N, Taketomi A, Shirabe K, Akashi K, Lleo A, Ansari AA, Gershwin ME, Maehara Y
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 165(2) Pages: 243-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Significance of periductal Langerhans cells and biliary epithelial cell-derived macrophage inflammatory protein-3a in the pathogenesis of primary biliary cirrhosis2011
- Author(s)
  Harada K, Shimoda S, Ikeda H, Chiba M, Hsu M, Sato Y, Kobayashi M, Ren XS, Ohta H, Kasashima S, Kawashima A, Nakanuma Y
- Journal Title
  
  Liver Int
  
  Volume: 31(2) Pages: 245-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Epigenetic investigation of variably X chromosome inactivated genes in monozygotic female twins discordant for primary biliary cirrhosis2011
- Author(s)
  Mitchell MM, Lleo A, Zammataro L, Mayo MJ, Invemizzi P, Bach N, Shimoda S, Gordon S, Podda M, Gershwin ME, Selmi C, LaSalle JM
- Journal Title
  
  Epigenetics
  
  Volume: Jan;6(1) Pages: 95-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Significance of periductal Langerhans cells and biliary epithelial cell-derived macrophage inflammatory protein-3α in the pathogenesis of primary biliary cirrhosis.2011
- Author(s)
  Harada K, Shimoda S, Ikeda H, Chiba M, Hsu M, Sato Y, Kobayashi M, Ren XS, Ohta H, Kasashima S, Kawashima A, Nakanuma Y.
- Journal Title
  
  Liver Int.
  
  Volume: 31(2) Pages: 245-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Intracellular B7-H4 suppresses bile duct epithelial cell apoptosis in human primary biliary cirrhosis2011
- Author(s)
  Chen Y, Guo G, Guo S, Shimoda S, Shroyer KR, Tang Y, Wu Y
- Journal Title
  
  Inflammation
  
  Volume: 34(6) Pages: 688-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Serum BAFF and APRIL levels in patients with PBC.2010
- Author(s)
  Migita K, Ilyassova B, Kovzel EF, Nersesov A, Abiru S, Maeda Y, Komori A, Ito M, Yano K, Yatsuhashi H, Shimoda S, Ishibashi H, Nakamura M
- Journal Title
  
  Clin Immunol
  
  Volume: Feb ; 134(2) Pages: 217-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Serum BAFF and APRIL levels in patients with PBC2010
- Author(s)
  Migita K, Ilyassova B, Kovzel EF, Nersesov A, Abiru S, Maeda Y, Komori A, Ito M, Yano K, Yatsuhashi H, Shimoda S, Ishibashi H, Nakamura M
- Journal Title
  
  Clin Immunol.Feb
  
  Volume: 134(2) Pages: 217-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC) The HLA-DRB1polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC2010
- Author(s)
  Nakamura M, Yasunami M, Kondo H, Horie H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Ito M, Shimoda S, Ishibashi H; PBC Study Group in NHOSLJ
- Journal Title
  
  Hepatol Res. May
  
  Volume: 40(5) Pages: 494-504
- NAID
  10026392072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] CX3CL1(fractalkine) : a signpost for biliary inflammation in primary biliary cirrhosis.2010
- Author(s)
  Shimoda S, Harada K, Niiro H, Taketomi A, Maehara Y, Tsuneyama K, Kikuchi K, Nakanuma Y, Mackay IR, Gershwin ME, Akashi K.
- Journal Title
  
  Hepatology
  
  Volume: Feb ; 51(2) Pages: 567-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] a signpost for biliary inflammation in primary biliary cirrhosis2010
- Author(s)
  Shimoda S, Harada K, Niiro H, Taketomi A, Maehara Y, Tsuneyama K, Kikuchi K, Nakanuma Y, Mackay IR, Gershwin ME, Akashi K CX3CL1 (fractalkine)
- Journal Title
  
  Hepatology. Feb
  
  Volume: 51(2) Pages: 567-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC) : The HLA-DRB1 polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC.2010
- Author(s)
  Nakamura M, Yasunami M, Kondo H, Horie H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Ito M, Shimoda S, Ishibashi H ; PBC Study Group in NHOSLJ
- Journal Title
  
  Hepatol Res
  
  Volume: May ; 40(5) Pages: 494-504
- NAID
  10026392072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Kyushu University Liver Disease Study Group.Pegylated interferon a-2b plus ribavirin for older patients with chronic hepatitis2010
- Author(s)
  Kainuma M, Furusyo N, Kajiwara E, Takahashi K, Nomura H, Tanabe Y, Satoh T, Maruyama T, Nakamuta M, Kotoh K, Azuma K, Shimono J, Shimoda S, Hayashi J
- Journal Title
  
  C. World J Gastroenterol
  
  Volume: 16(35) Pages: 4400-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590739
[Journal Article] Biliary epithelial cells and primary biliary cirrhosis : the role of liver-inf iltrating mononuclear cells2008
- Author(s)
  Shimoda S, et al.
- Journal Title
  
  Hepatology Mar ; 47(3)
  
  Pages: 958-965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590775
[Journal Article] CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in AMA-negative primary biliary cirrhosis2008
- Author(s)
  Shimoda S, et.al.
- Journal Title
  
  J Autoimmun
  
  Pages: 110-115
- Data Source
  KAKENHI-PROJECT-19590775
[Journal Article] Biliary epithelial cells and primary biliary cirrhosis : the role of liver-infiltrating mononuclear cells2008
- Author(s)
  Shimoda S, et.al.
- Journal Title
  
  Hepatology
  
  Pages: 958-965
- Data Source
  KAKENHI-PROJECT-19590775
[Journal Article] CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in A MA-negative primary biliary cirrhosis2008
- Author(s)
  Shimoda S, et al
- Journal Title
  
  J Autoimmun. Sep ; 31(2)
  
  Pages: 110-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590775
[Journal Article] Peripheral Tolerance and the Qualitative Characteristics of Autoreactive T Cell Clones in Primary Biliary Cirrhosis2007
- Author(s)
  Kawano, Shimoda S et.al.
- Journal Title
  
  The Journal of Immunology
  
  Pages: 3315-3324
- Data Source
  KAKENHI-PROJECT-19590775
[Journal Article] Peripheral Tolerance and the Qualitative Characteristics of Autoreactive T Cell Clones in Primary Biliary Cirrhosis2007
- Author(s)
  A. Kawano, S. Shimoda, et. al.
- Journal Title
  
  The Journal of Immunology 179
  
  Pages: 3315-3324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590775
[Journal Article] Autoreactive T-cell responses in primary biliary cirrhosis are proinflammatory whereas those of controls are regulatory.2006
- Author(s)
  Shimoda S, Ishikawa F, Kamihira T, Ishibashi H, et al.
- Journal Title
  
  Gastroenterology 131(2)
  
  Pages: 606-618
- NAID
  10019797097
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Autoreactive T-cell responses in primary biliary cirrhosis are proinflammatory whereas those of controls are regulatory2006
- Author(s)
  Shimoda S, Ishikawa F, Kamihira T, Komori A, Niiro H, Baba E, Harada K, Isse K, Nakanuma Y, Ishibashi H, Gershwin ME, Harada M
- Journal Title
  
  Gastroenterology 131(2)
  
  Pages: 606-618
- NAID
  10019797097
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.2006
- Author(s)
  Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira T, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Ishibashi H
- Journal Title
  
  Liver Int. 26(4)
  
  Pages: 467-476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Human intrahcpatic biliary cpithclial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways2006
- Author(s)
  Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira T, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Ishibashi H
- Journal Title
  
  Liver Int. 26(4)
  
  Pages: 467-476
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Adult T-cell leukemia development from a human T-cell leukemia virus type I carrier after a living-donor liver transplantation.2006
- Author(s)
  Kawano N, Shimoda K, Ishikawa F, Taketomi A, Yoshizumi T, Shimoda S, Yoshida S, Uozumi K, Suzuki S, Maehara Y, Harada M
- Journal Title
  
  Transplantation 27;82(6)
  
  Pages: 840-843
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways2006
- Author(s)
  Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira T, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Ishibashi H
- Journal Title
  
  Liver Int. 26(4)
  
  Pages: 467-76
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Autoreactive T-cell responses in primary biliary cirrhosis are proinflammatory whereas those of controls are regulatory2006
- Author(s)
  Shimoda S, Ishikawa F, Kamihira T, Komori A, Niiro H, Baba E, Harada K, Isse K, Nakanuraa Y, Ishibashi H, Gershwin ME, Harada M
- Journal Title
  
  Gastroenterology 131(2)
  
  Pages: 606-18
- NAID
  10019797097
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis2006
- Author(s)
  Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H
- Journal Title
  
  J Autoimmun. 26(2)
  
  Pages: 138-145
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] T cell immunity and graft-versus-host disease (GVHD).2006
- Author(s)
  Ichiki Y, Bowlus CL, Shimoda S, Ishibashi H, et al.
- Journal Title
  
  Autoimmun Rev. 5(1)
  
  Pages: 1-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Adult T-cell leukemia development from a human T-cell leukemia vinjs type l carrier after a living-donor liver transplantation.2006
- Author(s)
  Kawano N, Shimoda K, Ishikawa F, Taketomi A, Yoshizumi T, Shimoda S, Yoshida S, Uozumi K, Suzuki S, Maehara Y, Harada M.
- Journal Title
  
  Transplantation 27;82(6)
  
  Pages: 840-3
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Guidelines for therapy of the chronic inflammatory liver diseases.2006
- Author(s)
  Ishibashi H, Shimoda S, Nakamura M, Gershwin ME
- Journal Title
  
  Seminars in Liver Disease (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] The immune response to mitochondrial autoantigens.2006
- Author(s)
  Ishibashi H, Shimoda S, Gershwin ME.
- Journal Title
  
  Seminars in Liver Disease 25(3)
  
  Pages: 337-346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006
- Author(s)
  Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H
- Journal Title
  
  J.Autoimmunity 26(2)
  
  Pages: 138-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion2006
- Author(s)
  Ishikawa F, Shimazu H, Shultz LD, Fukata M, Nakamura R, Lyons B, Shimoda K, Shimoda S, Kanemaru T, Nakamura K, Ito H, Kaji Y, Perry AC, Harada M
- Journal Title
  
  FASEB J. 20(7)
  
  Pages: 950-952
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Autoreactive T-cell responses in primary biliary cirrhosis are proinflammatory whereas those of controls are regulatory2006
- Author(s)
  Shimoda S, Ishikawa F, Kamihira T, Komori A, Niiro H, Baba E, Harada K, Isse K, Nakanuma Y, Ishibashi H, Gershwin ME, Harada M.
- Journal Title
  
  Gastroenterology 26(4)
  
  Pages: 467-76
- NAID
  10019797097
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis.2006
- Author(s)
  Lan RY, Cheng C, Lian ZX, Tsuneyama K, Yang GX, Moritoki Y, Chuang YH, Nakamura T, Saito S, Shimoda S, Tanaka A, Bowlus CL, Takano Y, Ansari AA, Coppel RL, Gershwin M
- Journal Title
  
  Hepatology 43(4)
  
  Pages: 729-737
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590657
[Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005
- Author(s)
  Nakamura M, Shimizu-Yoshida Y, Shimoda S, Ishibashi H, et al.
- Journal Title
  
  Journal of Hepatology 42(3)
  
  Pages: 386-392
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis.2005
- Author(s)
  Mao TK, Lian ZX, Selmi C, Ichiki Y, Shimoda S, Ishibashi H, et al.
- Journal Title
  
  Hepatology 42(4)
  
  Pages: 802-808
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] The immune response to mitochondrial autoantigens.2005
- Author(s)
  Ishibashi H, Shimoda S, Gershwin ME.
- Journal Title
  
  Seminars in Liver Disease 25(3)
  
  Pages: 337-46
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Biliary epithelial cells regulate autoreactive T cells : Implications for biliary-specific diseases.2005
- Author(s)
  Kamihira T, Shimoda S, Nakamura M, Yokoyama T, Takii Y, Kawano A et al.
- Journal Title
  
  Hepatology 41
  
  Pages: 151-159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005
- Author(s)
  Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T, Ueki T, Daikoku M, Yano K, Matsumoto T, Migita K, Yatsuhashi H, Ito M, Masaki N, Adachi H, Watanabe Y, Nakamura Y, Saoshiro T, Sodeyama T, Koga M, Shimoda S, Ishibashi H
- Journal Title
  
  J.Hepatol. 42(3)
  
  Pages: 386-392
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Biliary epithelial cells regulate autoreactive T cells Implications for biliary-specific diseases.2005
- Author(s)
  Kamihira T, Shimoda S, Nakamura M, Takii Y, et al.
- Journal Title
  
  Hepatology 41
  
  Pages: 151-159
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] T cell immunity in hepatitis B and hepatitis C virus infection : implications for autoimmunity.2005
- Author(s)
  Ichiki Y, He XS, Shimoda S, Ishibashi H, Keeffe EB, Rossaro L, Gershwin ME.
- Journal Title
  
  Autoimmun Rev. 4(2)
  
  Pages: 82-95
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Mitochondrial antigens as targets of cellular and humoral auto-immunity in primary biliary cirrhosis.2005
- Author(s)
  Ichiki Y, Selmi C, Shimoda S, Ishibashi H, Gordon SC, Gershwin ME.
- Journal Title
  
  Clin Rev Allergy Immunol. 28(2)
  
  Pages: 83-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Biliary epithelial cells regulate autoreactive T cells : implications for biliary-specific diseases.2005
- Author(s)
  Kamihira T, Shimoda S, Nakamura M, Ishibashi H, et al.
- Journal Title
  
  Hepatology 41(1)
  
  Pages: 151-159
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] T Cell Immunity in Primary Biliary Cirrhosis.2004
- Author(s)
  Ishibashi H, Ichiki Y, Kamihira T, Shimoda S
- Journal Title
  
  Mucosal Immunology Update 14
  
  Pages: 10-12
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Is primary biliary cirrhosis a model autoimmune disease?2004
- Author(s)
  Ichiki Y, Shimoda S, Ishibashi H, Gershwin ME.
- Journal Title
  
  Autoimmun Rev. 3(4)
  
  Pages: 331-336
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Is primary biliary cirrhosis a model autoimmune disease?2004
- Author(s)
  Ichiki Y, Shimoda S, Ishibashi H, Gershwin ME
- Journal Title
  
  Autoimmunity Reviewiew 3(4)
  
  Pages: 331-336
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Innate immune responses in human intrahepatic biliary epithelial cells via Toll-like receptors.2004
- Author(s)
  Komori A, Yokoyama T, Takii Y, Nakamura M, Shimoda S et al.
- Journal Title
  
  AASLD Abstract #597 (October 31, 2004. Boston)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] T Cell Immunity in Primary Biliary Cirrhosis.2004
- Author(s)
  Ishibashi H, Ichiki Y, Kamihira T, Shimoda S.
- Journal Title
  
  Mucosal Immunology Update 14
  
  Pages: 10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Is primary biliary cirrhosis a model autoimmune disease?2004
- Author(s)
  Ichiki Y, Shimoda S, Ishibashi H, Gershwin ME.
- Journal Title
  
  Autoimmunity Review 3(4)
  
  Pages: 331-336
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Promiscuous T cells selected by Escherichia coli : OGDC-E2 in primary biliary cirrhosis.2003
- Author(s)
  Tanimoto H, Shimoda S, Ishibashi H, et al.
- Journal Title
  
  J Autoimmun. 20(3)
  
  Pages: 255-263
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] T cell immunity and primary biliary cirrhosis.2003
- Author(s)
  Ishibashi H., Nakamura M, Shimoda S, Gershwin ME.
- Journal Title
  
  Autoimmunity Reviews 2(1)
  
  Pages: 19-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Characterization of distinct costimulation dependent and independent autoreactive T cell clones in primary biliary cirrhosis.2003
- Author(s)
  Kamihira T, Shimoda S, Harada K, Kawano A, et al.
- Journal Title
  
  Gastroenterology 125
  
  Pages: 1379-87
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis.2003
- Author(s)
  Shimoda S, Nakamura M, Ishibashi H, et al.
- Journal Title
  
  Gastroenterology 124
  
  Pages: 1915-1925
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Characterization of distinct costimulation dependent and independent autoreactive T cell clones in primary biliary cirrhosis.2003
- Author(s)
  Kamihira T, Shimoda S, Harada K, Kawano A, Handa M, Baba E, Tsuneyama K, Nakamura M, Ishibashi H, et al.
- Journal Title
  
  Gastroenterology 125
  
  Pages: 1379-1387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Journal Article] Distinct costimulation dependent and independent autoreactive T-cell clones in primary biliary cirrhosis.2003
- Author(s)
  Kamihira T, Shimoda S, Harada K, Kawano A, Handa M, Baba E, Tsuneyama K, Nakamura M, Ishibashi H, Nakanuma Y, Gershwin ME, Harada M.
- Journal Title
  
  Gastroenterology 125(5)
  
  Pages: 1379-1387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390238
[Presentation] Identification of novel biliary epithelial cell biomarkers in primary biliary cholangitis (PBC).2019
- Author(s)
  Shimoda S, Harada K, Nakamura M , et al.
- Organizer
  AASLD THE LIVER MEETING 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 新たなPBC治療標的分子の同定と治療へのアプローチ.2019
- Author(s)
  下田慎治, 原田憲一、中村　稔
- Organizer
  第55回日本肝臓学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] PBC診断・治療バイオマーカーと新たな治療標的分子の確立.2019
- Author(s)
  下田慎治, 原田憲一、中村　稔
- Organizer
  第105回日本消化器病学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Integrated analysis of GWAS and mRNA microarray identified IFNG and CD40L as the central upstream-regulators in primary biliary cholangitis.2019
- Author(s)
  Ueno K, Aiba Y, Shimoda S, et al
- Organizer
  The International Liver Congress 2019 (ILC2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 技術革新がもたらした消化器研究のパラダイムシフト　PBC診断・治療バイオマーカーと新たな治療標的分子の確立2019
- Author(s)
  下田慎治, 原田憲一, 中村稔
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] Autoiimunity against biliary epithetial cells.2019
- Author(s)
  Shimoda S
- Organizer
  The Asian Pacific Association for the Study of the Liver
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] 自己免疫性肝疾患:病態解明と治療法の進歩　新たなPBC治療標的分子の同定と治療へのアプローチ,2019
- Author(s)
  下田慎治, 原田憲一, 中村稔
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] 胆管細胞・免疫細胞から明らかにする原発性胆汁性胆管炎の病態.2018
- Author(s)
  下田慎治
- Organizer
  第55回日本消化器免疫学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 胆管細胞・免疫細胞から明らかにする原発性胆汁性胆管炎の病態2018
- Author(s)
  下田慎治
- Organizer
  第55回日本消化器免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] Molecular mechanism of autoimmune liver diseases, especially PBC2018
- Author(s)
  Shimoda S
- Organizer
  「JSH-EASL Joint Session Autoimmune Liver Diseases including PBC and PSC: Europe and Japan」
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] 自己免疫性肝疾患の診断と治療の進歩 PBCで鍵となるIFN-g産生とUDCA有効性の疾患模倣培養系を用いたメカニズム解析2018
- Author(s)
  下田慎治
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] PBCでは病態に深く関与する免疫細胞からのIFN-g産生をUDCAが制御する2018
- Author(s)
  下田慎治
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] 原発性胆汁性胆管炎（PBC）模倣培養系とゲノムワイド関連解析（GWAS）を統合して得られる遺伝子情報の機能解析.2017
- Author(s)
  下田慎治, 小野原伸也, 中村　稔.
- Organizer
  第53回日本肝臓学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Increased expression and altered localization of cathepsin Z is associated with progression to jaundice-stage in primary biliary cholangitis.2017
- Author(s)
  Aiba Y, Harada K, Ito M, Aishima S, Hitomi Y, Nishida N, Kawashima M, Uemoto S, Kokudo N, Takatsuki M, Eguchi S, Shimoda S, Nakamura H, Komori A, Abiru S, Nagaoka S, Yatsuhashi H, Tokunaga K, Nakamura M.
- Organizer
  AASLD The Liver Meeting 2017.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 自己免疫性肝疾患のパラダイムシフト原発性胆汁性胆管炎(PBC)模倣培養系とゲノムワイド関連解析(GWAS)を統合して得られる遺伝子情報の機能解析2017
- Author(s)
  下田慎治, 小野原伸也, 中村稔
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] Immune responses in primary biliary cholangitis2017
- Author(s)
  Shinji Shimoda
- Organizer
  The 1st JSGE Asian Session
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] Genome-wide Association Studies Identify PRKCB as A Novel Genetic Susceptibility Locus for Primary Biliary Cholangitis in the Japanese Population.2017
- Author(s)
  Nakamura M, Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Komori A, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, PBC consortium in Japan.
- Organizer
  The 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL 2017).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Genome-wide Association Studies Identify PRKCB as A Novel Genetic Susceptibility Locus for Primary Biliary Cholangitis in the Japanese Population.2017
- Author(s)
  Nakamura M,　Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Komori A, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, PBC consortium in Japan.
- Organizer
  The 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL 2017)
- Place of Presentation
  Shanghai(China)
- Year and Date
  2017-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] 原発性胆汁性胆管炎(PBC)の新規治療開発に向けて2017
- Author(s)
  下田慎治, 小野原伸也, 中村　稔, 原田憲一.
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 難治性肝胆道疾患(PBC/PSC/AIH)診療の進歩と今後の課題原発性胆汁性胆管炎(PBC)の新規治療開発に向けて2017
- Author(s)
  下田慎治, 小野原伸也, 中村稔, 原田憲一
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] 原発性胆汁性胆管炎（PBC）模倣培養系とゲノムワイド関連解析（GWAS）を統合して得られる遺伝子情報の機能解析2017
- Author(s)
  下田慎治, 小野原伸也, 中村　稔
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] olecular mechanism of PBC2017
- Author(s)
  Shinji Shimoda
- Organizer
  The Asian Pacific Association for the Study of the Liver Single Topic Conference 2017 Nagasaki
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04164
[Presentation] WFA(+) -M2BP interacts with liver macrophages which activates hepatic stellate cells2016
- Author(s)
  Yuki Bekki, Ken Shirabe, Shinji Shimoda, Shinji Itoh, Toru Ikegami, Hideaki Uchiyama, Tomoharu Yoshizumi, Yoshihiko Maehara
- Organizer
  APASL 2016 in Tokyo
- Place of Presentation
  グランドプリンス新高輪
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04932
[Presentation] PBCでの胆管細胞AE2発現低下は慢性炎症性変化を亢進させる2016
- Author(s)
  下田慎治
- Organizer
  日本消化器病学会総会
- Place of Presentation
  新宿区
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26461012
[Presentation] PBC胆管炎を模倣したAE2発現低下による胆管細胞での慢性炎症の誘導2016
- Author(s)
  下田慎治
- Organizer
  日本肝臓学会総会
- Place of Presentation
  千葉市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26461012
[Presentation] 日本人原発性胆汁性肝硬変の疾患感受性遺伝子による病態の解明　シンポジウム1; PBC(原発性胆汁性肝硬変)-臨床、病理と免疫学との接点を求めて2015
- Author(s)
  中村稔, 川嶋実苗, 相葉佳洋, 西田奈央, 人見祐基, 小森敦正, 下田慎治, 田中　篤, 茶山一彰, 太平弘正, 山本和秀, 銭谷幹男, 小島　要, 長崎正朗, 徳永勝士
- Organizer
  第52回日本消化器免疫学会総会
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] 胆管細胞から明らかにするPBCの病態2015
- Author(s)
  下田慎治
- Organizer
  第５７回日本消化器病学会大会
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461012
[Presentation] HCV陽性肝硬変におけるT細胞機能に関する脾臓の役割2015
- Author(s)
  下田慎治、川中博文、前原喜彦
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K10169
[Presentation] 原発性胆汁性肝硬変におけるNK細胞による胆管細胞傷害機序の解析2015
- Author(s)
  下田慎治
- Organizer
  第４１回日本肝臓学会西部会
- Place of Presentation
  名古屋市
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26461012
[Presentation] HCV陽性肝硬変におけるT細胞機能に関する脾臓の役割2015
- Author(s)
  下田慎治
- Organizer
  第１０１回日本消化器病学会総会
- Place of Presentation
  仙台市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26461012
[Presentation] 原発性胆汁性肝硬変をモデルにした臓器特異的自己免疫疾患における自然免疫異常から獲得免疫異常へ移行するメカニズムの解析2015
- Author(s)
  下田慎治
- Organizer
  第５１回日本肝臓学会総会
- Place of Presentation
  熊本市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26461012
[Presentation] Natural killer cells regulate T cell immunity in primary biliary cirrhosis2015
- Author(s)
  Shinji Shimoda
- Organizer
  アメリカ肝臓学会(AASLD)
- Place of Presentation
  San Francisco
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461012
[Presentation] 原発性胆汁性肝硬変モデルマウスにおけるNK/NKT細胞の役割2012
- Author(s)
  下田慎治
- Organizer
  日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] 原発性胆汁性肝硬変における胆管上皮の疾患特異的自己抗原発現の探索2012
- Author(s)
  下田慎治
- Organizer
  日本肝臓学会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] 原発性胆汁性肝硬変における胆管破壊に関する新規知見2011
- Author(s)
  下田慎治
- Organizer
  日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] 原発性胆汁性肝硬変における病因病態の解析2011
- Author(s)
  下田慎治
- Organizer
  日本肝臓学会大会
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] 原発性胆汁性肝硬変の病態解明と新規治療の可能性2011
- Author(s)
  下田慎治
- Organizer
  日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] 原発性胆汁性肝硬変(PBC)における免疫異常の基礎とそれに基づく予後予測について2010
- Author(s)
  下田慎治
- Organizer
  JDDW 2010
- Place of Presentation
  横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] 原発性胆汁性肝硬変におけるCX3CL1産生の機序2010
- Author(s)
  下田慎治
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] 原発性胆汁性肝硬変における胆管CX3CL1発現に必要なTNFαは、主にTLR4リガンドで単球から産生される2010
- Author(s)
  下田慎治
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22590739
[Presentation] REDEFINING AMA NEGATIVE PRIMARY BILIARY CIHHHOSIS2008
- Author(s)
  下田慎治
- Organizer
  第59回アメリカ肝臓学会(AASLD)
- Place of Presentation
  San Francisco
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590775
[Presentation] 原発性胆汁性肝硬変から樹立した培養胆管細胞の解析2008
- Author(s)
  下田慎治
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-19590775
[Presentation] REDEFINING AMA NEGATIVE PRIMAEY BILIARY CIHHHOSIS2008
- Author(s)
  下田慎治
- Organizer
  第59回アメリカ肝臓学会(AASLD)
- Place of Presentation
  San Francisco
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590775
[Presentation] 原発性胆汁性肝硬変の発症機構と病態2008
- Author(s)
  下田慎治
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590775
[Presentation] 原発性胆汁性肝硬変(PBC)における自然免疫の関与2007
- Author(s)
  下田慎治, 他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19590775
[Presentation] 原発性胆汁性肝硬変における自己反応性T細胞の末梢寛容と質的特長2007
- Author(s)
  下田慎治
- Organizer
  2007日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19590775
[Presentation] 原発性胆汁性肝硬変における自然免疫の関与についての解析2007
- Author(s)
  下田慎治, 他
- Organizer
  第93回日本消化器病学会総会
- Place of Presentation
  青森
- Year and Date
  2007-04-21
- Data Source
  KAKENHI-PROJECT-19590775
[Presentation] 原発性胆汁性肝硬変の病態形成における疎水性胆汁酸とanion exchager2の関与
- Author(s)
  久本仁美, 岩坂翔, 隅田幸佑, 原田憲一, 下田慎治
- Organizer
  日本肝臓学会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26461012
[]
[]
[]
[]

1. Nakamura Minoru (40217906)

# of Collaborated Projects: 4 results

# of Collaborated Products: 33 results
2. Kawanaka Hirofumi (10363334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 川嶋実苗 (00396706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 人見祐基 (10525819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 安波道郎 (80244127)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 前原喜彦 (80165662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 吉住朋晴 (80363373)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. ISHIBASHI Hiromi (80127969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
9. MIGITA Kiyoshi (60264214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. KOMORI Atsumasa (50234901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. ITO Masahiro (30184691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. Shirabe Ken (70264025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 西田奈央 (50456109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 藤岡ひかる (00264226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
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# of Collaborated Projects: 1 results

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16. 赤星朋比古 (20336019)

# of Collaborated Projects: 1 results

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17. 成松久 (40129581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 久野敦 (50302287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 池上徹 (80432938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 佐藤隆 (90371046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山下洋市 (00404070)

# of Collaborated Projects: 1 results

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22. 池田哲夫 (60585701)

# of Collaborated Projects: 1 results

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23. 原田憲一 (30283112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
24. 有田誠 (80292952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 小島要 (10646988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 山口隆志 (10730202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. AIBA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 高槻光寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 山本靖彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 山本博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimoda Shinji 下田 慎治

下田 慎治 シモダ シンジ

SHIMODA Shinji 下田 慎治

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Co-Researchers

細胞老化の蓄積解除から切り開く新規肝疾患治療法の基盤開発

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Establishment of novel therapeutic strategies for primary biliary cholangitis by integrating omics and single cell analysis informationPrincipal Investigator

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Development of new treatment methods for primary biliary cholangitis by genome and lipid information from disease mimic culture systemPrincipal Investigator

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GWAS-based integrated analysis of PBC to dissect the mechanism of development and progression of primary biliary cholangitis

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Multidisciplinary treatment focusing on impaired intrahepatic microcirculation and splenic dysfunction in liver cirrhosis and portal hypertension

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The biological analysis of sugar chain signal between hepatic stelate cells and macrophages in the progression of liver fibrosis.

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Analysis of disease-pathways and molecular targets by disease-susceptibility genes in primary biliary cholangitis

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Clarification of the pathogenecity and the application of therapies from biliary epithelial cells in primary biliary cholangitisPrincipal Investigator

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The mechanism of bile duct destruction in Primary Biliary CirrhosisPrincipal Investigator

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Innate and acquired immunity for primary biliary cirrhosisPrincipal Investigator

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The roles for biliary epithelial cells as antigen presenting cells or target cells in primary biliary cirrhosisPrincipal Investigator

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Dissection of autoimmune response and establishment of diagnosis and treatment of primary biliary cirrhosis

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[Book] 肝臓病の最新治療(戸田剛太郎,沖田極,門田守人,井廻道夫,幕内雅敏,恩地森一,森正樹,茶山一彰,持田智,銭谷幹男編集)2006

Author(s)

Shimoda Shinji 下田慎治

下田慎治シモダシンジ

SHIMODA Shinji 下田慎治