Murai Yasuo 村井保夫

… Alternative Names

村井保夫ムライヤスオ

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Researcher Number	30287750
Other IDs	https://orcid.org/0000-0002-9753-1873
Affiliation (Current)	2025: 日本医科大学, 大学院医学研究科, 大学院教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 日本医科大学, 大学院医学研究科, 大学院教授 2022: 日本医科大学, 医学部, 大学院教授 2018 – 2022: 日本医科大学, 医学部, 准教授 2001 – 2002: 日本医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery Except Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 52040:Radiological sciences-related / Basic Section 56010:Neurosurgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 血管狭窄 / RNF213 / 遺伝子 / 脳動脈瘤 / 内頸動脈 / もやもや病 / 中大脳動脈 / 内頸動脈狭窄 / RNF / 内頸動脈瘤 … More / もやもや病 / 遺伝子解析 / ミスセンス / モヤモヤ病 / 動脈瘤 / 遺伝子変異 / 内頸動脈閉塞症 / 脳血管障害 / 脳神経外科 / Prolifeaion / Pituitary adenoma / Immunohistochemistry / Biological marker / MIB-1 / RCAS1 / pituitary adenoma / Pituirtary … More Except Principal Investigator 脳動脈瘤 / バイオインフォマティクス / う蝕原性細菌 / 未破裂脳動脈瘤 / くも膜下出血 / intestinal flora / oral flora / intracranial aneurysms / subarachnoid hemorrhage / 播種性血管内凝固症候群 / 敗血症 / ICU獲得性筋力低下 / 脳萎縮 / 人工呼吸 / 4D Flow MRI / preventive medicine / microorganism / 腸ー脳相関 / bioproduct / 動物モデル / 口腔細菌 / 遺伝子解析 / バイオプロダクト / 体内細菌叢 / bioinformatics / micorbiota / intestinal bacteria / oral bacteria / cerebral aneurysm / stroke / vessel wall injury / 16sRNA / bioproducts / 炎症 / 細菌性心内膜炎 / Streptcoccus mutans / 発生 / 破裂 / 腸内細菌 / 口腔内細菌 / control / international / bacterial flora / intracranial aneurysm / 遺伝子 / 口腔内細菌叢 / 腸ー能相関 / 代謝産物 / 国際比較 / 腸内細菌叢 / data trnasfer / bioinfromatics / incidence difference / International study / Swiss / Finland / Intracranial aneurysm / Ruputre risk / Intersitinal flora / Oral bacteria / Subarachnoid hemorrhage Less

CFDと4D Flow MRIのデータ同化技術を活用した脳潅流圧推定法の開発と臨床妥当性評価
- Principal Investigator
  
  関根鉄朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Nippon Medical School
敗血症患者における急速進行性脳萎縮とPICSやICU-AWとの関連性に関する研究
- Principal Investigator
  
  中江竜太
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nippon Medical School
脳動脈瘤の臨床表現型に着目したRNF213の網羅的解析Principal Investigator
- Principal Investigator
  
  村井保夫
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
Why subarachnoid hemorrhage occure more frequentry in Japanese than other population?
- Principal Investigator
  
  Morita Akio
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nippon Medical School
Elucidation of the effect of Microorganism of the body on the origin and rupture of the intracranial aneurysms and development of preventive measure of the subarachnoid hemorrhage
- Principal Investigator
  
  Morita Akio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
Identification of expression mechanism by comprehensive gene analysis of Moyamoya disease analogous vascular stenosisPrincipal Investigator
- Principal Investigator
  
  Murai Yasuo
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
下垂体腺腫の増殖能、浸潤能における分子生物学的検討Principal Investigator
- Principal Investigator
  
  村井保夫
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nippon Medical School

All 2024 2022 2021 2020

All Journal Article Presentation

[Journal Article] RNF213-related vasculopathy: various systemic vascular diseases involving RNF213 gene mutations: Review2024
- Author(s)
  Murai Y, et al
- Journal Title
  
  Journal of nippon medical school
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09294
[Journal Article] A Case of Moyamoya Syndrome Associated With Multiple Endocrine Neoplasia Type 2A.2021
- Author(s)
  Matano F(1), Murai Y(1), Watanabe A(2), Shirokane K(1), Igarashi
- Journal Title
  
  Front Endocrinol (Lausanne)
  
  Volume: 12 Pages: 703410-703410
- DOI
  10.3389/fendo.2021.703410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09008, KAKENHI-PROJECT-22K16671
[Journal Article] RNF213 c.14576G>A Is Associated with Intracranial Internal Carotid Artery Saccular Aneurysms.2021
- Author(s)
  Murai Y(1), Ishisaka E(1), Watanabe A(2)(3), Sekine T(4), Shirokane K(1), Matano F(1), Nakae R(5), Tamaki T(6), Koketsu K(1), Morita A(1).
- Journal Title
  
  Genes (Basel).
  
  Volume: 23 Issue: 10 Pages: 1468-1468
- DOI
  10.3390/genes12101468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09008, KAKENHI-PROJECT-21K07686
[Journal Article] Role of RNF213 polymorphism in defining quasi-moyamoya disease and definitive moyamoya disease.2021
- Author(s)
  Ishisaka E(1), Watanabe A(2)(3), Murai Y(1), Shirokane K(4), Matano F(1), Tsukiyama A(1), Baba E(1), Nakagawa S(1), Tamaki T(4), Mizunari T(5), Tanikawa R(6), Morita A(1).
- Journal Title
  
  Neurosurg Focus.
  
  Volume: 51 Issue: 3 Pages: E2-E2
- DOI
  10.3171/2021.5.focus21182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09008
[Journal Article] Ring finger protein 213 c.14576G>A mutation is not involved in internal carotid artery and middle cerebral artery dysplasia.2021
- Author(s)
  Murai Y(1), Ishisaka E(2), Watanabe A(3)(4), Sekine T(5), Shirokane K(2), Matano F(2), Nakae R(6), Tamaki T(7), Koketsu K(2), Morita A(2).
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Issue: 1 Pages: 22163-22163
- DOI
  10.1038/s41598-021-01623-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09008, KAKENHI-PROJECT-21K07686
[Journal Article] White Matter Lesions as Brain Frailty and Age are Risk Factors for Surgical Clipping of Unruptured Intracranial Aneurysms in the Elderly.2020
- Author(s)
  171.Matano F, Mizunari T, Murai Y, Tamaki T, Tateyama K, Suzuki M, Morita A.
- Journal Title
  
  J Stroke Cerebrovasc Dis.
  
  Volume: 29 Issue: 10 Pages: 1-5
- DOI
  10.1016/j.jstrokecerebrovasdis.2020.105121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0208
[Presentation] STA-MCA bypass の基本　－術中の配慮と術前後管理－2024
- Author(s)
  村井保夫ら
- Organizer
  日本脳卒中の外科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09294
[Presentation] 人工呼吸に伴う急速進行性脳萎縮2024
- Author(s)
  中江竜太、関根鉄朗、田上隆、五十嵐豊、村井保夫、横堀將司
- Organizer
  第51回日本集中治療医学会
- Data Source
  KAKENHI-PROJECT-23K08484
[Presentation] RNF213 mutation is not involved in internal carotid artery and middle cerebral artery dysplasia2022
- Author(s)
  尾関友博:] 村井保夫:1, 石坂栄太郎:2, 関根鉄朗:3, 白銀一貴:1, 亦野文宏:1, 中江竜太:4, 纐纈健太:5, 玉置智規:6, 水成隆之:5, 森田明夫:1
- Organizer
  日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09008
[Presentation] 内頸動脈および中大脳動脈形成異常とRNF213変異の関係2022
- Author(s)
  尾関友博:] 村井保夫:1, 石坂栄太郎:2, 関根鉄朗:3, 白銀一貴:1, 亦野文宏:1, 中江竜太:4, 纐纈健太:5, 玉置智規:6, 水成隆之:5, 森田明夫:1
- Organizer
  Stroke 2022
- Data Source
  KAKENHI-PROJECT-18K09008
[Presentation] もやもや病関連遺伝子変異 RNF213（c.14576G>A）の頭蓋内内頸動脈嚢状動脈瘤における検討2021
- Author(s)
  村井保夫1,石坂栄太郎2,渡邉淳3,4,白銀一貴5,亦野文宏1,纐纈健太6,玉置智規5,水成隆之6,森田明夫1
- Organizer
  日本医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-18K09008

1. 亦野文宏 (70557511)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. Morita Akio (60302725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 渡邉淳 (10307952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 青木友浩 (40633144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 関根鉄朗 (00747826)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 大継將寿 (40803086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 白銀一貴 (70573236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 仲野和彦 (00379083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 清水則夫 (30226245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 筋野智久 (40464862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 塩澤裕介 (60801511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 野崎和彦 (90252452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 嶺貴彦 (00631293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大谷智仁 (40778990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中江竜太 (20786975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 田上隆 (40626272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 横堀将司 (70449271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YOKOBORI Shouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murai Yasuo 村井 保夫

村井 保夫 ムライ ヤスオ

Research Projects

Research Products

Co-Researchers

CFDと4D Flow MRIのデータ同化技術を活用した脳潅流圧推定法の開発と臨床妥当性評価

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

敗血症患者における急速進行性脳萎縮とPICSやICU-AWとの関連性に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳動脈瘤の臨床表現型に着目したRNF213の網羅的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Why subarachnoid hemorrhage occure more frequentry in Japanese than other population?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the effect of Microorganism of the body on the origin and rupture of the intracranial aneurysms and development of preventive measure of the subarachnoid hemorrhage

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of expression mechanism by comprehensive gene analysis of Moyamoya disease analogous vascular stenosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

下垂体腺腫の増殖能、浸潤能における分子生物学的検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] RNF213-related vasculopathy: various systemic vascular diseases involving RNF213 gene mutations: Review2024

Author(s)

Journal Title

Data Source

[Journal Article] A Case of Moyamoya Syndrome Associated With Multiple Endocrine Neoplasia Type 2A.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNF213 c.14576G>A Is Associated with Intracranial Internal Carotid Artery Saccular Aneurysms.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of RNF213 polymorphism in defining quasi-moyamoya disease and definitive moyamoya disease.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ring finger protein 213 c.14576G>A mutation is not involved in internal carotid artery and middle cerebral artery dysplasia.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] White Matter Lesions as Brain Frailty and Age are Risk Factors for Surgical Clipping of Unruptured Intracranial Aneurysms in the Elderly.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] STA-MCA bypass の基本 －術中の配慮と術前後管理－2024

Author(s)

Organizer

Data Source

Murai Yasuo 村井保夫

村井保夫ムライヤスオ

[Presentation] STA-MCA bypass の基本　－術中の配慮と術前後管理－2024

[Presentation] もやもや病関連遺伝子変異 RNF213（c.14576G>A）の頭蓋内内頸動脈嚢状動脈瘤における検討2021