Sujino Tomohisa 筋野智久

Researcher Number	40464862
Other IDs	https://orcid.org/0000-0003-0699-6577
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2019 – 2025: 慶應義塾大学, 医学部(信濃町), 講師 2018: 慶應義塾大学, 医学部(信濃町), 特任講師 2017: 慶應義塾大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53010:Gastroenterology-related / Gastroenterology / General internal medicine and related fields Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 49070:Immunology-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator 炎症性腸疾患 / 制御性T細胞 / 腸管免疫 / 脳腸相関 / 脳腸連関 / 大腸炎 / Ahrシグナル / 制御性T 細胞 / ２光子顕微鏡 / 2光子顕微鏡 … More / 免疫学 / 内科 / 腸管上皮内ＣD4Ｔ細胞 / 腸管上皮内Ｔ細胞 / 腸管免疫細胞 / 肥満 / 腸炎 / レプチン … More Except Principal Investigator 炎症性腸疾患 / シングルセル解析 / 転写因子 / 腸管上皮間リンパ球 / 小腸疾患 / 潰瘍性大腸炎 / トランスクリプトーム / GLP-2 / 腸内細菌叢 / single cell transriptome / GLP-2アナログ製剤 / 短腸症候群 / 免疫細胞1細胞解析 / 潰瘍性大腸炎県連腫瘍 / 小腸移植 / 大腸炎 / preventive medicine / microorganism / 腸ー脳相関 / bioproduct / 動物モデル / 口腔細菌 / バイオインフォマティクス / 遺伝子解析 / バイオプロダクト / う蝕原性細菌 / 体内細菌叢 / 未破裂脳動脈瘤 / くも膜下出血 / bioinformatics / micorbiota / intestinal bacteria / oral bacteria / cerebral aneurysm / stroke / vessel wall injury / 16sRNA / bioproducts / oral flora / intestinal flora / subarachnoid hemorrhage / intracranial aneurysms / 炎症 / 細菌性心内膜炎 / Streptcoccus mutans / 発生 / 破裂 / 腸内細菌 / 口腔内細菌 / 脳動脈瘤 / 走査電顕 / 超拡大内視鏡 / 腸管上皮 / 走査電子顕微鏡 Less

腸管enteric nerveによる記憶免疫構築機構の探索Principal Investigator
- Principal Investigator
  
  筋野智久
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
細胞動態に着目した炎症抑制性腸管上皮間リンパ球の分化誘導機構の解明
- Principal Investigator
  
  大野恵子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Keio University
シングルセル解析を利用した潰瘍性大腸炎関連腫瘍部、非腫瘍部の免疫細胞解析
- Principal Investigator
  
  高林馨
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Keio University
微小環境変化により小腸免疫細胞の1細胞時空間的制御機構破綻がひきおこす疾患の理解Principal Investigator
- Principal Investigator
  
  筋野智久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Keio University
GLP-2アナログ製剤治療によって誘導される小腸上皮single cell transcriptome解析
- Principal Investigator
  
  山田洋平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Keio University
Understanding endoscopic morphology during immune reconstitution using single cell analysis of small intestinal disease
- Principal Investigator
  
  細江直樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Keio University
Understanding the Ahr signal for the maintainance of intestinal epithelial cells
- Principal Investigator
  
  Ogata Haruhiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Keio University
Mechanism of differentiation of intraepithelial lymphocytes with anti-inflammatory properties.
- Principal Investigator
  
  KEIKO Ono
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Keio University
免疫細胞の腸管内における局在、動態を支配する腸管神経シグナルの探索Principal Investigator
- Principal Investigator
  
  筋野智久
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
Single cell analysis in gut by using multi-photon imagingPrincipal Investigator
- Principal Investigator
  
  SUJINO Tomohisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Keio University
Elucidation of the effect of Microorganism of the body on the origin and rupture of the intracranial aneurysms and development of preventive measure of the subarachnoid hemorrhage
- Principal Investigator
  
  Morita Akio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
Elucidation of human intestinal epithelial function using ultra-magnification endoscopy and nano-level observation by scanning electron microscopy
- Principal Investigator
  
  HOSOE Naoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Keio University
Spatiotemporal analysis and pathogenesis of proinflammatory regulatory T cells in intestinal villiPrincipal Investigator
- Principal Investigator
  
  SUJINO Tomohisa
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
Analyse of Leptin signal in Inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  Sujino Tomohisa
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Keio University
Elucidation of the genetic regulation of novel intestinal intraepithelial lymphocytes with anti-inflammatory propertiesPrincipal Investigator
- Principal Investigator
  
  SUJINO Tomohisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Video capsule endoscopy in overt and occult obscure gastrointestinal bleeding: Insights from a single‐center, observational study in Japan2024
- Author(s)
  Tojo Anna、Sujino Tomohisa、Hayashi Yukie、Kamiya Kenji J L Limpias、Sato Moe、Hinako Sakurai、Yoshimatsu Yusuke、Kinoshita Satoshi、Kiyohara Hiroki、Mikami Yohei、Takabayashi Kaoru、Kato Motohiko、Ogata Haruhiko、Kanai Takanori、Hosoe Naoki
- Journal Title
  
  DEN Open
  
  Volume: 4 Issue: 1
- DOI
  10.1002/deo2.354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07994
[Journal Article] Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development2023
- Author(s)
  Ono Keiko、Sujino Tomohisa、Miyamoto Kentaro、Harada Yosuke、Kojo Satoshi、Yoshimatsu Yusuke、Tanemoto Shun、Koda Yuzo、Zheng Jiawen、Sayama Kazutoshi、Koide Tsuyoshi、...、Mucida Daniel、Taniuchi Ichiro、Kanai Takanori
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41467-023-40950-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23K18213, KAKENHI-PROJECT-19KK0177, KAKENHI-PROJECT-21K07084, KAKENHI-PLANNED-19H05747, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-23K27590
[Journal Article] A Roadmap for the Human Gut Cell Atlas2023
- Author(s)
  Zilbauer Matthias、、、Sujino Tomohisa、Human Cell Atlas Gut Biological Network Consortium
- Journal Title
  
  Nature Reviews Gastroenterology & Hepatology
  
  Volume: 20 Issue: 9 Pages: 597-614
- DOI
  10.1038/s41575-023-00784-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23K27590
[Journal Article] Usefulness of texture and color enhancement imaging in assessing mucosal healing in patients with ulcerative colitis2023
- Author(s)
  Hayashi Yukie、Takabayashi Kaoru、Kato Motohiko、Tojo Anna、Aoki Yasuhiro、Hagihara Yuya、Yoshida Kosuke、Yoshimatsu Yusuke、Kiyohara Hiroki、Sugimoto Shinya、Nanki Kosaku、Mikami Yohei、Sujino Tomohisa、Mutaguchi Makoto、Kawaguchi Takaaki、Hosoe Naoki、Yahagi Naohisa、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Gastrointestinal Endoscopy
  
  Volume: 97 Issue: 4 Pages: 759-766.e1
- DOI
  10.1016/j.gie.2022.11.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-21K19540, KAKENHI-PROJECT-21K16010
[Journal Article] D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease2023
- Author(s)
  Umeda Satoko、　Sujino Tomohisa、、、Shiomi Daisuke、Ashida Hiroshi、Kanai Takanori
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 16 Issue: 6 Pages: 1011-1031
- DOI
  10.1016/j.jcmgh.2023.08.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23K17415, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27404, KAKENHI-PROJECT-23K27590
[Journal Article] 今月の主題小腸画像診断のトピックスノート -新しい小腸画像診断のトピックス-パワースパイラル内視鏡2023
- Author(s)
  細江直樹、筋野智久、髙林馨、加藤元彦、金井隆典、東條杏奈、櫻井陽奈子、林由紀恵、吉松裕介、杉本真也、木下聡、清原裕貴、三上洋平
- Journal Title
  
  胃と腸
  
  Volume: 58 Issue: 11 Pages: 1518-1521
- DOI
  10.11477/mf.1403203405
- ISSN
  0536-2180, 1882-1219
- Year and Date
  2023-11-25
- Data Source
  KAKENHI-PROJECT-22K07994
[Journal Article] The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis2023
- Author(s)
  Miyamoto Kentaro、Sujino Tomohisa、...、Kanai Takanori
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 113005-113005
- DOI
  10.1016/j.celrep.2023.113005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22H04995, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27590
[Journal Article] Chronic Enteropathy Associated with <i>Solute Carrier Organic Anion Transporter Family, Member 2A1 (SLCO2A1)</i> with Positive Immunohistochemistry for SLCO2A1 Protein2022
- Author(s)
  Ariake Chizuru、Hosoe Naoki、Sakurai Hinako、Tojo Anna、Hayashi Yukie、JL Limpias Kamiya Kenji、Sujino Tomohisa、Takabayashi Kaoru、Kosaki Kenjiro、Seki Satowa、Hisamatsu Tadakazu、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 17 Pages: 2607-2611
- DOI
  10.2169/internalmedicine.8939-21
- NAID
  130008161632
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21H02905
[Journal Article] Enrichment of type I interferon signaling in colonic group 2 innate lymphoid cells in experimental colitis2022
- Author(s)
  Irie Emi、Ishihara Rino、Mizushima Ichiro、Hatai Shunya、Hagihara Yuya、Takada Yoshiaki、Tsunoda Junya、Iwata Kentaro、Matsubara Yuta、Yoshimatsu Yusuke、Kiyohara Hiroki、Taniki Nobuhito、Sujino Tomohisa、Takabayashi Kaoru、Hosoe Naoki、Ogata Haruhiko、Teratani Toshiaki、Nakamoto Nobuhiro、Mikami Yohei、Kanai Takanori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 01-10
- DOI
  10.3389/fimmu.2022.982827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07994, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05123, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-20H03666, KAKENHI-PROJECT-21H02906, KAKENHI-PROJECT-21J12194
[Journal Article] Development of a Deep-Learning Algorithm for Small Bowel-Lesion Detection and a Study of the Improvement in the False-Positive Rate2022
- Author(s)
  Hosoe Naoki、Horie Tomofumi、Tojo Anna、Sakurai Hinako、Hayashi Yukie、Limpias Kamiya Kenji Jose-Luis、Sujino Tomohisa、Takabayashi Kaoru、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 13 Pages: 3682-3682
- DOI
  10.3390/jcm11133682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07994
[Journal Article] Efficacy of Calcineurin Inhibitors for Induction of Remission in Intestinal Beh?et’s Disease2022
- Author(s)
  Kawaguchi Takaaki、Fukata Masayuki、Omori Teppei、Kiyohara Hiroki、Sugimoto Shinya、Nanki Kosaku、Sujino Tomohisa、Mikami Yohei、Kanai Takanori
- Journal Title
  
  Crohn's & Colitis 360
  
  Volume: 4 Issue: 3 Pages: 1-10
- DOI
  10.1093/crocol/otac017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-21K19540
[Journal Article] Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes2022
- Author(s)
  Harada Y, Sujino T, Miyamoto K, Nomura E, Yoshimatsu Y, Tanemoto S, Umeda S, Ono K, Mikami Y, Nakamoto N, Takabayashi K, Hosoe N, Ogata H, Ikenoue T, Hirao A, Kubota Y, Kanai T.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 4 Pages: 104021-104021
- DOI
  10.1016/j.isci.2022.104021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-19H03397, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-21K07084, KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-22K07994, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K19502
[Journal Article] Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut2022
- Author(s)
  Yoshimatsu Yusuke、Sujino Tomohisa、Hosoe Naoki、et al.
- Journal Title
  
  Cell Reports
  
  Volume: 39 Issue: 6 Pages: 110773-110773
- DOI
  10.1016/j.celrep.2022.110773
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07994, KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-19H03455, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21H02905
[Journal Article] Effectiveness and Durability of Ustekinumab Therapy With or Without Immunomodulators for Ulcerative Colitis Patients in Japan2022
- Author(s)
  Aoki Yasuhiro、Sujino Tomohisa、Kawaguchi Takaaki、Sugimoto Shinya、Shimada Fumie、Yoshimatsu Yusuke、Kiyohara Hiroki、Nanki Kosaku、Mikami Yohei、Takabayashi Kaoru、Hosoe Naoki、Ogata Haruhiko、Iwao Yasushi、Kanai Takanori
- Journal Title
  
  Crohn's & Colitis 360
  
  Volume: 4 Issue: 2 Pages: 1-10
- DOI
  10.1093/crocol/otac010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-21K19540
[Journal Article] Protocol to isolate and enrich mouse splenic naive CD4+ T?cells for in?vitro CD4+CD8αα+ cell induction2022
- Author(s)
  Harada Yosuke、Miyamoto Kentaro、Sujino Tomohisa
- Journal Title
  
  STAR Protocols
  
  Volume: 3 Issue: 4 Pages: 101728-101728
- DOI
  10.1016/j.xpro.2022.101728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-20H03665
[Journal Article] Epithelium Replacement Contributes to Field Expansion of Squamous Epithelium and Ulcerative Colitis?Associated Neoplasia2022
- Author(s)
  Sugimoto Shinya、Iwao Yasushi、Shimoda Masayuki、Takabayashi Kaoru、Sato Toshiro、Kanai Takanori、Keio IBD Collaborators
- Journal Title
  
  Gastroenterology
  
  Volume: 162 Issue: 1 Pages: 334-337
- DOI
  10.1053/j.gastro.2021.09.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K19540, KAKENHI-PROJECT-21K16010, KAKENHI-PROJECT-20H03746
[Journal Article] Feasibility and Safety of Endoscopic Ischemic Polypectomy and Clinical Outcomes in Patients with Peutz?Jeghers Syndrome (with Video)2022
- Author(s)
  Limpias Kamiya Kenji J. L.、Hosoe Naoki、Takabayashi Kaoru、Okuzawa Anna、Sakurai Hinako、Hayashi Yukie、Miyanaga Ryoichi、Sujino Tomohisa、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: - Issue: 1 Pages: 252-258
- DOI
  10.1007/s10620-022-07477-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21H02905
[Journal Article] Single-cell transcriptomics of human gut T cells identifies cytotoxic CD4+CD8A+ T cells related to mouse CD4 cytotoxic T cells2022
- Author(s)
  Tanemoto Shun,Sujino Tomohisa,Miyamoto Kentaro,Moody Jonathan,Yoshimatsu Yusuke,Ando Yoshinari,Koya Ikuko,Harada Yosuke,Tojo Anna Okuzawa,Ono Keiko,Hayashi Yukie,Takabayashi Kaoru,Okabayashi Koji,Teratani Toshiaki,Mikami Yohei,Nakamoto Nobuhiro,Hosoe Naoki,Ogata Haruhiko,Hon Chung-Chau,Shin Jay W,Kanai Takanori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 977117-977117
- DOI
  10.3389/fimmu.2022.977117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07084, KAKENHI-PROJECT-22K07994, KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-21H02906
[Journal Article] CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells2021
- Author(s)
  Koda Yuzo、Teratani Toshiaki、Chu Po-Sung、Hagihara Yuya、Mikami Yohei、Harada Yosuke、Tsujikawa Hanako、Miyamoto Kentaro、Suzuki Takahiro、Taniki Nobuhito、Sujino Tomohisa、Sakamoto Michiie、Kanai Takanori、Nakamoto Nobuhiro
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 4474-4474
- DOI
  10.1038/s41467-021-24734-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21H02906, KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-20H04129
[Journal Article] Host-microbe cross-talk governs amino acid chirality to regulate survival and differentiation of B cells2021
- Author(s)
  Suzuki Masataka、Sujino Tomohisa、Chiba Sayako、Harada Yoichi、Goto Motohito、Takahashi Riichi、Mita Masashi、Hamase Kenji、Kanai Takanori、Ito Mamoru、Waldor Matthew Kaden、Yasui Masato、Sasabe Jumpei
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 10
- DOI
  10.1126/sciadv.abd6480
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07181, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K18272
[Journal Article] Significance of endoscopic deep small bowel evaluation using balloon-assisted enteroscopy for Crohn's disease in clinical remission2021
- Author(s)
  Takabayashi K, Hosoe N, Kato M, Hayashi Y, Nanki K, Fukuhara K, Mikami Y, Mizuno S, Sujino T, Mutaguchi M, Naganuma M, Yahagi N, Ogata H, Kanai T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 56(1) Issue: 1 Pages: 25-33
- DOI
  10.1007/s12328-020-01261-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-19K22624
[Journal Article] Characteristics of the Mucosal Surface on Scanning Electron Microscopy in Patients with Remitting Ulcerative Colitis2021
- Author(s)
  Nomura E, Sujino T, Hosoe N, Yoshimatsu Y, Tanemoto S, Takabayashi K, Mutaguchi M, Shimoda M, Naganuma M, Ogata H, Kanai T.
- Journal Title
  
  Dig Dis Sci.
  
  Volume: - Issue: 9 Pages: 1-6
- DOI
  10.1007/s10620-020-06609-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-19K16592, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-20H03665
[Journal Article] Various Endoscopic Features in Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma2021
- Author(s)
  Aoki Yasuhiro、Sujino Tomohisa、Takabayashi Kaoru、Mutakuchi Makoto、Emoto Katsura、Hosoe Naoki、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Case Reports in Gastroenterology
  
  Volume: 1 Issue: 1 Pages: 312-322
- DOI
  10.1159/000513902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-19K22624
[Journal Article] Predictors of necessity for endoscopic balloon dilatation in patients with Crohn's disease-related small bowel stenosis2021
- Author(s)
  Yukie Hayashi, Kaoru Takabayashi, Naoki Hosoe, Hiroki Kiyohara, Satoshi Kinoshita, Kosaku Nanki, Kayoko Fukuhara, Yohei Mikami, Tomohisa Sujino, Makoto Mutaguchi, Takaaki Kawaguchi, Motohiko Kato, Haruhiko Ogata, Takanori Kanai
- Journal Title
  
  Ann Med.
  
  Volume: 53 Issue: 1 Pages: 2025-2033
- DOI
  10.1080/07853890.2021.1998597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K16010, KAKENHI-PROJECT-23K20316
[Journal Article] Clinical, Endoscopic, and Pathological Characteristics of Immune Checkpoint Inhibitor-Induced Gastroenterocolitis2021
- Author(s)
  Hayashi Y, Hosoe N, Takabayashi K, Limpias Kamiya KJL, Tsugaru K, Shimozaki K, Hirata K, Fukuhara K, Fukuhara S, Mutaguchi M, Sujino T, Sukawa Y, Hamamoto Y, Naganuma M, Takaishi H, Shimoda M, Ogata H, Kanai T.
- Journal Title
  
  Dig Dis Sci.
  
  Volume: - Issue: 6 Pages: 1-6
- DOI
  10.1007/s10620-020-06441-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-19K22624
[Journal Article] Current status of colon capsule endoscopy.2021
- Author(s)
  Hosoe N, Limpias Kamiya KJL, Hayashi Y, Sujino T, Ogata H, Kanai T.
- Journal Title
  
  Dig Endosc
  
  Volume: 33(4) Issue: 4 Pages: 529-537
- DOI
  10.1111/den.13769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-17H05082
[Journal Article] Stepwise chromatin and transcriptional acquisition of an intraepithelial lymphocyte program2021
- Author(s)
  London Mariya、Bilate Angelina M.、Castro Tiago B. R.、Sujino Tomohisa、Mucida Daniel
- Journal Title
  
  Nature Immunology
  
  Volume: 22 Issue: 4 Pages: 449-459
- DOI
  10.1038/s41590-021-00883-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K18272
[Journal Article] Significance of endoscopic deep small bowel evaluation using balloon-assisted enteroscopy for Crohn’s disease in clinical remission2020
- Author(s)
  Takabayashi Kaoru、Hosoe Naoki、Kato Motohiko、Hayashi Yukie、Nanki Kosaku、Fukuhara Kayoko、Mikami Yohei、Mizuno Shinta、Sujino Tomohisa、Mutaguchi Makoto、Naganuma Makoto、Yahagi Naohisa、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 1 Pages: 25-33
- DOI
  10.1007/s00535-020-01737-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18KK0246
[Journal Article] Clinical and Endoscopic Characteristics of Pyogenic Granuloma in the Small Intestine: A Case Series with Literature Review2020
- Author(s)
  Hayashi Yukie、Hosoe Naoki、Takabayashi Kaoru、Kamiya Kenji JL Limpias、Mutaguchi Makoto、Miyanaga Ryoichi、Hirata Kenro、Fukuhara Seiichiro、Mikami Yohei、Sujino Tomohisa、Masugi Yohei、Naganuma Makoto、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 4 Pages: 501-505
- DOI
  10.2169/internalmedicine.3745-19
- NAID
  130007798397
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-02-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-17H05082
[Journal Article] Mucosal concentrations of N-acetyl-5-aminosalicylic acid is related to endoscopic activity in ulcerative colitis patients with mesalamine.2020
- Author(s)
  Fukuda T, Naganuma M, Takabayashi K, Hagihara Y, Tanemoto S, Nomura E, Yoshimatsu Y, Sugimoto S, Nanki K, Mizuno S, Mikami Y, Fukuhara K, Sujino T, Mutaguchi M, Inoue N, Ogata H, Iwao Y, Abe T, Kanai T.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 35 Issue: 11 Pages: 1878-1885
- DOI
  10.1111/jgh.15059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08381, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-18KK0246
[Journal Article] The liver-brain-gut neural arc maintains the Treg cell niche in the gut2020
- Author(s)
  Teratani T, Mikami Y, Nakamoto N, Suzuki T, Harada Y, Okabayashi K, Hagihara Y, Taniki N, Kohno K, Sibata S, Miyamoto K, Ishigame H, Chu Po-Sung, Sujino T, Suda W, Hattori M, Matsui M, Okada T, Okano H, Inoue M, Yada T, Kitagawa Y, Yoshimura A, Tanida M, Tsuda M, Iwasaki Y, Kanai T.
- Journal Title
  
  Nature
  
  Volume: 585 Issue: 7826 Pages: 591-596
- DOI
  10.1038/s41586-020-2425-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22611, KAKENHI-PROJECT-20K17062, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-17H06175, KAKENHI-PROJECT-19H05658, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-19H04045, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03666, KAKENHI-PROJECT-20H04133, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18K14840, KAKENHI-PROJECT-18KK0246
[Journal Article] Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35.2019
- Author(s)
  Koda Y, Nakamoto N, Chu P, Ugamura A, Teratani T, Shiba S, Taniki N, Sujino T, Miyamoto K, Mikami Y, Suzuki T, Yamaguchi A, Morikawa R, Sato K, Yoshimoto T, Kanai K.
- Journal Title
  
  J Clin Invest
  
  Volume: 129(8) Issue: 8 Pages: 3201-3213
- DOI
  10.1172/jci125863
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-18K11658, KAKENHI-PROJECT-19K06570, KAKENHI-PROJECT-19K09105, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18K15794
[Journal Article] Efficacy of Novel Ultrathin Single-Balloon Enteroscopy for Crohn's Disease: A Propensity Score-Matched Study2019
- Author(s)
  Takabayashi Kaoru、Hosoe Naoki、Kato Motohiko、Hayashi Yukie、Miyanaga Ryoichi、Nanki Kosaku、Fukuhara Kayoko、Mikami Yohei、Mizuno Shinta、Sujino Tomohisa、Mutaguchi Makoto、Naganuma Makoto、Yahagi Naohisa、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Gut and Liver
  
  Volume: - Issue: 5 Pages: 1-6
- DOI
  10.5009/gnl19228
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-18KK0246
[Journal Article] Development of an Indigo Naturalis Suppository for Topical Induction Therapy in Patients with Ulcerative Colitis2019
- Author(s)
  Yoshimatsu Yusuke、Naganuma Makoto、Sugimoto Shinya、Tanemoto Shun、Umeda Satoko、Fukuda Tomohiro、Nomura Ena、Yoshida Kosuke、Ono Keiko、Mutaguchi Makoto、Nanki Kosaku、Mizuno Shinta、Mikami Yohei、Fukuhara Kayoko、Sujino Tomohisa、Takabayashi Kaoru、Ogata Haruhiko、Iwao Yasushi、Kanai Takanori
- Journal Title
  
  Digestion
  
  Volume: 1 Issue: 4 Pages: 1-7
- DOI
  10.1159/000501152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-17H05082
[Journal Article] Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.2018
- Author(s)
  Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai MM, Nomura E, Harada Y, Aoki R, Koda Y, Mikami Y, Mizuno S, Naganuma M, Hisamatsu T, Kanai T.
- Journal Title
  
  Cell Mol Gastroenterol Hepatol.
  
  Volume: 7 Issue: 1 Pages: 135-156
- DOI
  10.1016/j.jcmgh.2018.09.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-17K19668, KAKENHI-PROJECT-17K15966, KAKENHI-PROJECT-18KK0246
[Journal Article] Intestinal immune response is regulated by gut microbe2017
- Author(s)
  TANEMOTO Shun、SUJINO Tomohisa、KANAI Takanori
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 40 Issue: 6 Pages: 408-415
- DOI
  10.2177/jsci.40.408
- NAID
  130006319639
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17K19668, KAKENHI-PROJECT-17H05082
[Journal Article] Steroid-refractory extensive enteritis complicated by ulcerative colitis successfully treated with adalimumab2017
- Author(s)
  Okabayashi Shinji、Kobayashi Taku、Sujino Tomohisa、Ozaki Ryo、Umeda Satoko、Toyonaga Takahiko、Saito Eiko、Nakano Masaru、Tablante Maria Carla、Morinaga Shojiroh、Hibi Toshifumi
- Journal Title
  
  intestinal research
  
  Volume: 15 Issue: 4 Pages: 535-535
- DOI
  10.5217/ir.2017.15.4.535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19668, KAKENHI-PROJECT-17H05082
[Presentation] 短腸症候群におけるGLP-2アナログ製剤の使用経験.2023
- Author(s)
  工藤裕実, 山田洋平, 筋野智久, 伊藤よう子, 前田悠太郎, 城崎浩司, 山岸徳子, 金森洋樹, 高橋信博, 加藤源俊, 黒田達夫.
- Organizer
  第60回日本小児外科学会学術集会. 大阪.
- Data Source
  KAKENHI-PROJECT-23K08037
[Presentation] 短腸症候群に対するGLP-2アナログ製剤による栄養学的変化.2023
- Author(s)
  工藤裕実 , 山田洋平, 高橋信博, 筋野智久, 熊谷知子, 杉山祥基, 伊藤よう子 , 城崎浩司, 前田悠太郎, 加藤源俊 , 狩野元宏, 藤野明浩.
- Organizer
  秋季シンポジウム / PSJM 2023
- Data Source
  KAKENHI-PROJECT-23K08037
[Presentation] 短腸症候群におけるGLP-2アナログ製剤の使用経験2023
- Author(s)
  工藤裕実, 山田洋平, 筋野智久, 伊藤よう子, 前田悠太郎, 城崎浩司, 山岸徳子, 金森洋樹, 高橋信博, 加藤源俊, 岡林剛史, 細江直樹, 黒田達夫.
- Organizer
  第52回小児消化管機能研究会. 東京.
- Data Source
  KAKENHI-PROJECT-23K08037
[Presentation] 小腸グラフト摘出による残存小腸20cm短腸症候群に対するGLP-2アナログ製剤の使用経験.2023
- Author(s)
  工藤裕実, 山田洋平, 筋野智久, 熊谷知子, 杉山祥基, 伊藤よう子, 城崎浩司, 前田悠太郎, 加藤源俊 , 狩野元宏, 藤野明浩.
- Organizer
  第33回日本小児外科QOL研究会.
- Data Source
  KAKENHI-PROJECT-23K08037
[Presentation] 当施設での腸管機能不全患者に対する多面的アプローチ2023
- Author(s)
  腸管不全治療の現状と課題　当施設での腸管機能不全患者に対する多面的アプローチ城崎浩司, 山田洋平, 伊藤よう子, 工藤裕実, 金森洋樹, 加藤源俊, 筋野智久, 長谷川康, 松原健太郎, 岡林剛史, 細江直樹, 尾原秀明, 藤野明浩
- Organizer
  第59回　日本移植学会総会
- Data Source
  KAKENHI-PROJECT-22K07994
[Presentation] 走査型電子顕微鏡を用いた潰瘍性大腸炎の粘膜評価2019
- Author(s)
  256.野村絵奈, 筋野智久, 細江直樹, 岩男泰, 緒方晴彦, 長沼誠, 下田将之, 水野慎大, 牟田口真, 福田知広, 亀山香織, 金井隆典
- Organizer
  第36回日本大腸検査学会総会
- Data Source
  KAKENHI-PROJECT-19K08402
[Presentation] skin inflammation induce gut inflammation by altering host microbe and immune system2018
- Author(s)
  筋野智久
- Organizer
  免疫学会 2019
- Data Source
  KAKENHI-PROJECT-17H05082
[Presentation] intestinal CD4CD8aa cells development in gut2017
- Author(s)
  Tomohisa Sujino
- Organizer
  Mucosal Immunology conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19668

1. HOSOE Naoki (90317131)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. KEIKO Ono (50645611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Morita Akio (60302725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Ogata Haruhiko (30177117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 仲野和彦 (00379083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 清水則夫 (30226245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 村井保夫 (30287750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 青木友浩 (40633144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 塩澤裕介 (60801511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 野崎和彦 (90252452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 高林馨 (60573342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山田洋平 (60383816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. MIKAMI Yohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. IWASAKI Yusaku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 善本隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 鈴木将貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 寺谷俊昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 金井隆典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 長沼誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 矢田俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 下田将之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sujino Tomohisa 筋野 智久

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腸管enteric nerveによる記憶免疫構築機構の探索Principal Investigator

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微小環境変化により小腸免疫細胞の1細胞時空間的制御機構破綻がひきおこす疾患の理解Principal Investigator

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免疫細胞の腸管内における局在、動態を支配する腸管神経シグナルの探索Principal Investigator

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Single cell analysis in gut by using multi-photon imagingPrincipal Investigator

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Spatiotemporal analysis and pathogenesis of proinflammatory regulatory T cells in intestinal villiPrincipal Investigator

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Analyse of Leptin signal in Inflammatory bowel diseasePrincipal Investigator

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Sujino Tomohisa 筋野智久

[Journal Article] 今月の主題小腸画像診断のトピックスノート -新しい小腸画像診断のトピックス-パワースパイラル内視鏡2023