NIIYAMA Hiroshi 新山寛

… Alternative Names

新山寛ニイヤマヒロシ

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Researcher Number	30309778
Affiliation (Current)	2025: 久留米大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 久留米大学, 医学部, 助教 2012: 久留米大学, 医学部, 助教 2010 – 2011: 久留米大学, 医学部, 講師 2000 – 2004: 久留米大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hygiene / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator マーカー / 心血管障害 / 心不全 / 心筋障害 / 予防医学 / リモデリング / 遺伝子治療 / aortic banded model / 心筋リモデリング / HVJ-liposome法 … More / flk-1 / VEGF / c-Met / HGF … More Except Principal Investigator TGF-β / MCP-1 / interferon-gamma / gene therapy / hypertension / myocardial fibrosis / 高血圧 / 心筋線維化 / 拡張障害 / 心不全 / 遺伝子治療 / アンジオテニシンII / 予後予測 / 予後予測因子 / バイオマーカー / サルコペニア / Gene of 7ND / OLETF Rat / Cardiac Fibrosis / Cardiac Remodeling / Heart Failure / 酸化ストレス / 炎症細胞浸潤 / 心・血管リモデリング / 左室拡張不全 / 7ND遺伝子 / OLETFラット / 心リモデリング / 生活習慣病 / macrophages / hypertrophy / blood pressure variability / 拡張能障害 / 接着因子 / リモデリング / アンジオテンシンII / ケモカイン / 線維化 / 炎症 / 血圧変動 / atherosclerosis / グラフト不全 / 新生内膜増生 / STAT3 / インターフェロンγ / 動脈硬化 / neutralizing antibody / diastolic dysfunction / 拡張不全 / TGF-beta / サイトカイン / 高脂血症 / がん / 細胞移植 / 遺伝子発現 / 再生医学 / 血管新生 Less

バイオマーカーを用いた新規サルコペニア指標の心疾患サルコペニア悪化・予後予測能
- Principal Investigator
  
  甲斐久史
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kurume University
Persistent on-going myocardial necrosis in general populationPrincipal Investigator
- Principal Investigator
  
  NIIYAMA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kurume University
骨髄単核細胞移植療法による虚血肢の遺伝子発現変化の網羅的解析と遺伝子治療への応用
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
EFFECTS OF EXAGGERATED BLOOD PRESSURE VARIABILITY ON CARDIAC REMODELING AND PERIVASCULAR INFLAMMATION
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
A possible treatment strategy for cardiovascular remodeling by metabolic syndrome-The gene therapy for use of MCP-1 7ND mutated gene-
- Principal Investigator
  
  KUWAHARA Fumitaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
NEW TREATMENT FOR DIASTOLIC DYSFUNCTION BY PREVENTING CARDIAC FIBROSIS -GENE THERAPY USING A MUTANT TGF-β, RECEPTOR-
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
PREVENTION OF VASCULAR REMODELING BY INHIBITING EARLY INFLAMMATORY PROCESS - GENE THERAPY USING A MUTANT INTERFERON-GAMMA RECEPTOR GENE -
- Principal Investigator
  
  SEKI Yukihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
心リモデリング過程における血管新生の関与-HGF遺伝子導入による血管新生の誘導-Principal Investigator
- Principal Investigator
  
  新山寛
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University

All 2024 2023 2022 2021 2020 2019 2011 2010 2004 2003

All Journal Article Presentation

[Journal Article] Low serum brain-derived neurotrophic factor may predict poor response to cardiac rehabilitation in patients with cardiovascular disease2024
- Author(s)
  Tsukada Yuya、Nishiyama Yasuhiro、Kishimoto Michiya、Nago Takeshi、Harada Haruhito、Niiyama Hiroshi、Katoh Atsushi、Matsuse Hiroo、Kai Hisashi
- Journal Title
  
  PLOS ONE
  
  Volume: 19 Issue: 2 Pages: e0298223-e0298223
- DOI
  10.1371/journal.pone.0298223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Angiotensin II receptor blocker and statin combination therapy associated with higher skeletal muscle index in patients with cardiovascular disease: A retrospective study.2022
- Author(s)
  Harada H, Niiyama H, Katoh A, Kai H.
- Journal Title
  
  J Clin Pharmacy Ther.
  
  Volume: 47 Issue: 1 Pages: 89-96
- DOI
  10.1111/jcpt.13540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies2021
- Author(s)
  Kai Hisashi、Kai Mamiko、Niiyama Hiroshi、Okina Norihito、Sasaki Motoki、Maeda Takanobu、Katoh Atsushi
- Journal Title
  
  Hypertension Research
  
  Volume: 44 Issue: 8 Pages: 955-968
- DOI
  10.1038/s41440-021-00641-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Increased arterial velocity pulse index is an independent factor related to skeletal muscle mass reduction and tissue damage in patients with cardiovascular disease2020
- Author(s)
  Harada H、Ikeda H、Nishiyama Y、Niiyama H、Katoh A、Kai H
- Journal Title
  
  Hypertension Research
  
  Volume: 43 Issue: 6 Pages: 534-542
- DOI
  10.1038/s41440-020-0404-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Low blood pressure and cardiovascular events in diabetic patients with coronary artery disease after revascularization: The CREDO-Kyoto Registry Cohort-1.2020
- Author(s)
  Kai H, Katoh A, Harada H, Niiyama H, Furukawa Y, Kimura T.
- Journal Title
  
  Hypertens Res
  
  Volume: 43 Issue: 7 Pages: 715-723
- DOI
  10.1038/s41440-020-0407-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Random Skin Biopsy in Patient With Rapidly Progressive Exertional Dyspnea2020
- Author(s)
  Kai H、Hamamura H、Niiyama H、Katoh A、Mouri F、Nagafuji K、Ohshima K、Yamaguchi R、Mukohara K
- Journal Title
  
  Circulation Reports
  
  Volume: 2 Issue: 1 Pages: 69-70
- DOI
  10.1253/circrep.CR-19-0120
- NAID
  130007784349
- ISSN
  2434-0790
- Year and Date
  2020-01-10
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Long-chain fatty acids in sarcopenia patients with cardiovascular diseases importance of n-9 monounsaturated fatty acids.2020
- Author(s)
  Katoh A, Ikeda H, Matsushima Y, Sasaki M, Okina N, Niiyama H, Nishiyama Y, Kai H.
- Journal Title
  
  JCSM Clinical Reports
  
  Volume: 5 Issue: 4 Pages: 121-128
- DOI
  10.1002/crt2.27
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion.2010
- Author(s)
  Huang NF, Niiyama H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 30 Pages: 984-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590564
[Journal Article] Repeated gene transfers of naked prostacyclin synthase plasmid into skeletal muscles attenuate monocrotaline-induced pulmonary hypertension and prolong survival in rats.2004
- Author(s)
  Tahara N, Kai H, Niiyama H, Mori T, Sugi Y, Takayama N, Yasukawa H, Numaguchi Y, Matsui H, Okamura K, Imaizumi T.
- Journal Title
  
  Human Gene Ther 15(12)
  
  Pages: 1270-1278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization..2004
- Author(s)
  Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T.
- Journal Title
  
  J Am Coll Cardiol 44(3)
  
  Pages: 661-666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization.2004
- Author(s)
  Niiyama H, Imaizumi T (全8名8番目)
- Journal Title
  
  J Am Coll Cardiol 44(3)
  
  Pages: 661-666
- Data Source
  KAKENHI-PROJECT-15659191
[Journal Article] Rho-kinase inhibition reduces neointima formation after vascular injury by enhancing Bax expression and apoptosis2003
- Author(s)
  Shibata R, Kai H, Seki Y, Kusaba K, Takemiya K, Koga M, Jalalidin A, Tokuda K, Tahara N, Niiyama H, Nagata T, Kuwahara F, Imaizumi T.
- Journal Title
  
  J Cardiovasc Pharmacol 42(suppl)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Presentation] 心不全患者の心臓リハビリテーション反応不良を予測する2023
- Author(s)
  塚田裕也、西山安浩、茅島大樹、古賀有里、原田晴仁、佐々木基起、翁徳仁、新山寛、加藤宏司、甲斐久史
- Organizer
  第28回日本心臓リハビリテーション学会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 心血管疾患患者における内服薬剤と骨格筋量との関連－単施設後向き横断研究2022
- Author(s)
  原田晴仁、西山安浩、福田由香、佐々木基起、翁　徳仁、新山　寛、加藤宏司、甲斐久史
- Organizer
  第28回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Novel and simple index using biomarkers for detecting sarcopenia in patients with cardiovascular disease.2022
- Author(s)
  Harada H, Nishiyama Y, Niiyama H, Katoh A, Kai H.
- Organizer
  International Society of Hypertension (ISH) / Asian Pacitic Society of Hypertension (APSH) / Japanese Society of Hypertension (JSH) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 循環器疾患患者における心機能と脂肪酸代謝との関係2022
- Author(s)
  加藤宏司、塚田裕也、古賀有里、福田由香、佐々木基起、翁徳仁、新山　寛、原田晴仁、西山安浩、甲斐久史
- Organizer
  第28回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Angiotensin II receptor blocker and statin combination therapy associated with higher skeletal muscle index in patients with cardiovascular disease.2022
- Author(s)
  Harada H, Nishiyama Y, Niiyama H, Katoh A, Kai H.
- Organizer
  International Society of Hypertension (ISH) / Asian Pacitic Society of Hypertension (APSH) / Japanese Society of Hypertension (JSH) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Long-chain fatty acids in sarcopenia patients with cardiovascular disease importance of n-9 monounsaturated fatty acids2022
- Author(s)
  Katoh A, Morita M, Sasaki M, Okina N, Niiyama H, Kai H.
- Organizer
  International Society of Hypertension (ISH) / Asian Pacitic Society of Hypertension (APSH) / Japanese Society of Hypertension (JSH) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Skeletal muscle mass reduction associated with increased arterial velocity pulse index and tissue damage marker in patients with cardiovascular disease.2022
- Author(s)
  Harada H, Nishiyama Y, Niiyama H, Katoh A, Kai H.
- Organizer
  International Society of Hypertension (ISH) / Asian Pacitic Society of Hypertension (APSH) / Japanese Society of Hypertension (JSH) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 久留米大学医療センターにおける高血圧・循環器病制圧と心臓リハビリテーションへの取り組み2021
- Author(s)
  加藤宏司、福田由香、佐々木基起、翁徳仁、新山寛、原田晴仁、西山安浩、古賀有里、田島陽子、塚田裕也、坂口美紀、飯田みさき、毛利聡代、甲斐久史
- Organizer
  第27回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 心血管患者における骨格筋量と内服薬剤の関連―後向きコホート研究2021
- Author(s)
  原田晴仁、福田由香、佐々木元基、翁徳仁、新山寛、加藤宏司、甲斐久史
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 運動能に及ぼす脂肪酸分画の影響2021
- Author(s)
  加藤宏司、福田由香、佐々木基起、翁徳仁、新山寛、原田晴仁、西山安浩、古賀有里、田島陽子、塚田裕也、坂口美紀、飯田みさき、毛利聡代、甲斐久史
- Organizer
  第27回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 循環器疾患患者における運動能と脂肪酸代謝の関係2020
- Author(s)
  加藤宏司、岸本迪也、古賀有里、田浦陽子、塚田裕也、坂口美紀、佐々木基起、翁徳仁、新山寛、原田晴仁、西山安浩、池田久雄、甲斐久史.
- Organizer
  第26回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 糖尿病合併冠動脈疾患における血圧低値と心血管イベント発症.2020
- Author(s)
  甲斐久史、加藤宏司、新山寛、甲斐麻美子、古川裕、木村剛．
- Organizer
  第35回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 皮膚生検により診断された急速に進行する労作性呼吸困難の一例2019
- Author(s)
  甲斐久史、松島慶央、佐々木基起、翁徳仁、新山寛、加藤宏司、山口倫
- Organizer
  第2回日本腫瘍循環器学会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Is low blood pressure an independent risk for cardiovascular events in diabetic patients with coronary artery disease after revascularization? - The CREDO-Kyoto cohort-12019
- Author(s)
  Kai H, Katoh A, Niiyama H, Harada H, Kimura T, Furukawa Y
- Organizer
  European Society of Hypertension 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Biomarker-based index for detecting sarcopenia in patients with cardiovascular disease2019
- Author(s)
  Kai H, Harada H, Niiyama H, Katoh A
- Organizer
  European Society of Cardiology ASIA with APSC & AFC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Low diastolic blood pressure is not an independent risk for cardiovascular death in revascularized coronary artery disease patients2011
- Author(s)
  Kai H, Niiyama H, 他5名5番目
- Organizer
  European Society of Cardiology Congress 2011
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] Low diastolic blood pressure is not an independent risk for cardiovascular death inrevascularized coronary artery disease patients.2010
- Author(s)
  Kai H, Niiyama H
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22590564

1. KAI Hisashi (60281531)

# of Collaborated Projects: 7 results

# of Collaborated Products: 26 results
2. KUWAHARA Fumitaka (90279167)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. IMAIZUMI Tsutomu (60148947)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. ANEGAWA Takahiro (00511833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YASUOKA Suguru (10461435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ADACHI Hisashi (40212518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAJIMOTO Hidemi (50349700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKEMIYA Kiyoko (20535075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SEKI Yukihiko (00279168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AKASHI Hidetoshi (80184084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGATA Tsuyoshi (70289429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 徳田圭亮 (80320191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 翁徳仁 (10412503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
14. 佐々木基起 (60725026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
15. 加藤宏司 (70279165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
16. 豊増謙太 (50837672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NIIYAMA Hiroshi 新山 寛

新山 寛 ニイヤマ ヒロシ

Research Projects

Research Products

Co-Researchers

バイオマーカーを用いた新規サルコペニア指標の心疾患サルコペニア悪化・予後予測能

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Persistent on-going myocardial necrosis in general populationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨髄単核細胞移植療法による虚血肢の遺伝子発現変化の網羅的解析と遺伝子治療への応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EFFECTS OF EXAGGERATED BLOOD PRESSURE VARIABILITY ON CARDIAC REMODELING AND PERIVASCULAR INFLAMMATION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A possible treatment strategy for cardiovascular remodeling by metabolic syndrome-The gene therapy for use of MCP-1 7ND mutated gene-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NEW TREATMENT FOR DIASTOLIC DYSFUNCTION BY PREVENTING CARDIAC FIBROSIS -GENE THERAPY USING A MUTANT TGF-β, RECEPTOR-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PREVENTION OF VASCULAR REMODELING BY INHIBITING EARLY INFLAMMATORY PROCESS - GENE THERAPY USING A MUTANT INTERFERON-GAMMA RECEPTOR GENE -

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心リモデリング過程における血管新生の関与-HGF遺伝子導入による血管新生の誘導-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Low serum brain-derived neurotrophic factor may predict poor response to cardiac rehabilitation in patients with cardiovascular disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Angiotensin II receptor blocker and statin combination therapy associated with higher skeletal muscle index in patients with cardiovascular disease: A retrospective study.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased arterial velocity pulse index is an independent factor related to skeletal muscle mass reduction and tissue damage in patients with cardiovascular disease2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low blood pressure and cardiovascular events in diabetic patients with coronary artery disease after revascularization: The CREDO-Kyoto Registry Cohort-1.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Random Skin Biopsy in Patient With Rapidly Progressive Exertional Dyspnea2020

Author(s)

NIIYAMA Hiroshi 新山寛

新山寛ニイヤマヒロシ