KAI Hisashi 甲斐久史

Researcher Number	60281531
Affiliation (Current)	2022: 久留米大学, その他部局等, 教授
Affiliation (based on the past Project Information) *help	2016 – 2021: 久留米大学, その他部局等, 教授 2015 – 2017: 久留米大学, 医学部, 教授 2007 – 2014: Kurume University, 医学部, 准教授 2003 – 2006: 久留米大学, 医学部, 助教授 2000 – 2002: 久留米大学, 循環器病研究所, 助教授 … More 1999 – 2000: 久留米大学, 医学部, 助手 1999: 久留米大学, 医学部・循環器病研究所, 講師 1998: 久留米大学, 医学部, 講師 1996 – 1997: 久留米大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / Cardiovascular medicine / Basic Section 53020:Cardiology-related Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / Hygiene / Cardiovascular medicine / Epidemiology and preventive medicine / Functional biochemistry / Applied pharmacology
Keywords	Principal Investigator 高血圧 / 炎症 / 心不全 / hypertension / 細胞増殖 / 血管平滑筋細胞 / 血圧変動 / 線維化 / TGF-β / 拡張障害 … More / myocardial fibrosis / Gタン白質共役型受容体キナーゼ / プロテインキナーゼC / プロテインキナーゼD / 遺伝子導入 / RhoA / ホスホリパーゼD / ホスホリバーゼC / ホスホリパーゼC / 低分子量G蛋白質 / 性差医学 / 分子生物学 / 心筋細胞 / 血管平滑筋 / 遺伝子発現 / 細胞間クロストーク / 心肥大 / 心臓リモデリング / 血管リモデリング / 遺伝子治療 / 心筋線維化 / TGF-beta / 拡張不全 / diastolic dysfunction / gene therapy / neutralizing antibody / ケモカイン / アンジオテンシンII / リモデリング / 接着因子 / アンジオテニシンII / 拡張能障害 / blood pressure variability / hypertrophy / macrophages / 臓器障害 / 細胞・組織 / 動脈硬化 / organ damage / heart failure / inflammation / cell, tissue / atherosclerosis / 内科系臨床医学・臨床心臓学 / 冠動脈疾患 / 抗血小板薬 / 抗凝固薬 / 抗血栓療法 / 危険因子 / 頭蓋内微小出血 / 頭部MRI / 頭蓋内出血 / MRI / リスク層別化 / サルコペニア / バイオマーカー / 予後予測 … More Except Principal Investigator 遺伝子治療 / 動脈硬化 / STAT3 / サイトカイン / atherosclerosis / JAK / STAT / TGF-β / 細胞移植 / 血管内皮 / 一酸化窒素 / 予防医学 / 心不全 / 遺伝子導入 / monocyte chemoattractant protein-1 / 心筋線維化 / interferon-gamma / gene therapy / MCP-1 / SOCS / SPRR1A / gp130 / 移植後冠動脈硬化 / 心臓移植 / TNF-α / リモデリング / 血管新生 / 再生医学 / 遺伝子発現 / がん / 高脂血症 / アンジオテニシンII / 腎不全 / Asymmetric Dimethylarginine / ADMA / 心筋障害 / 心血管障害 / マーカー / 血圧脈波 / 心血管リスク / 慢性腎不全 / 血管病 / 血管内皮機能 / 血管石灰化 / 血圧変動 / 脳梗塞 / 予後 / 機能予後 / 単球走化因子 / 最狭窄 / 炎症 / 再狭窄 / monocyte chemoattactant protein-1 / ケモカイン / アンジオテンシンII / gene transfer / restenosis / inflammation / インターフェロン / エリスロポエチン / 胎児造血 / c-Cbl / tyrosine kinase / CIS / cytokine / knockout mice / tyrosine phosphorylation / kinase inhibitor / 圧負荷肥大心モデル / 心筋リモデリング / 可溶性TβRII-IgGキメラ遺伝子 / HVJリポゾーム / HVJリポソーム / 可溶性TβRIIIgGキメラ遺伝子 / HVJリボソーム / myocardial fibrosis / hypertension / diastolic dysfunction / pressure-overloaded hearts / インターフェロンγ / 新生内膜増生 / グラフト不全 / 肺高血圧症 / モノクロタリン / プロスタグランジン合成酵素 / シクロオキシゲナーゼ合成酵素 / 肺高血圧 / レトロウイルス / レトロウイルスベクター / pulmonary hypertension / prostacyclin / stem cel / cell transplantation / macrophages / 更年期 / hot flush / hot flushモデルマウス / ニフェジピン誘発flushing / hot flush治療法 / ホルモン補充療法 / 大豆イソフラボン / スタチン系薬剤 / Ca^<2+> channel antagonist / nifedipine / ovariectomy / hot flushes / menopause / tail skin temperature / soybean isoflavones / estradiol replacement / 生活習慣病 / 心リモデリング / OLETFラット / 7ND遺伝子 / 左室拡張不全 / 心・血管リモデリング / 炎症細胞浸潤 / 酸化ストレス / Heart Failure / Cardiac Remodeling / Cardiac Fibrosis / OLETF Rat / Gene of 7ND / マクロファージ / インターロイキン6 / SOCS3 / 酸化LDL / マクロファージ泡沫化 / macrophage / Interleukin-6 / 心筋の生存 / 心筋虚血 / メカニカルストレス / IL-6 / 心肥大 / 再環流障害 / 圧負荷 / 心筋肥大 / 心筋アポトーシス / remodeling / biomechanical stress / ischemia / MAP kinase Less

バイオマーカーを用いた新規サルコペニア指標の心疾患サルコペニア悪化・予後予測能Principal Investigator
- Principal Investigator
  
  甲斐久史
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kurume University
Risk Stratification of Cerebral Bleeding during Antithrombotic TherapyPrincipal Investigator
- Principal Investigator
  
  Kai Hisashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kurume University
Blood Pressure Variability and Functional Outcome After Acute Ischemic Stroke: Fukuoka Stroke Registry
- Principal Investigator
  
  Fukuda Kenji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Kurume University
The mechanism of vascular calcification and endothelial dysfunction in chronic kidney disease
- Principal Investigator
  
  KAJIMOTO HIDEMI
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kurume University
Key Molecule of Aggravation of Hypertensive Organ Damage by Large Blood Pressure VariabilityPrincipal Investigator
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Persistent on-going myocardial necrosis in general population
- Principal Investigator
  
  NIIYAMA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kurume University
Are platelet-derived / endothelial cell-derived microparticles risks for cardiovascular events in general population?
- Principal Investigator
  
  YASUOKA Suguru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kurume University
Mechanism of Endothelial Dysfunction in Chronic Kidney Disease
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Analysis of the Crosstalk between Myocardium and Vasculature:Mechanism of Prevention of Hypertension by Intervention in Prehypertensive StagePrincipal Investigator
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Gender differences in the mechanism of hypertensive organ damage in the heartPrincipal Investigator
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Roles of inflammation in hypertensive organ damagesPrincipal Investigator
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Analysis of cytokine inducible gene small proline-rich protein 1A(SPRR1A) in cardiomyocyte
- Principal Investigator
  
  NAGATA Tsuyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Analysis of the role of signaling suppressor SOCS3 in the development of atherosclerosis
- Principal Investigator
  
  YASUKAWA Hideo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
骨髄単核細胞移植療法による虚血肢の遺伝子発現変化の網羅的解析と遺伝子治療への応用
- Principal Investigator
  
  今泉勉
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
New Therapeutic Method for Hot Flushes in Menopausal Women
- Principal Investigator
  
  KAI Mamiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University
EFFECTS OF EXAGGERATED BLOOD PRESSURE VARIABILITY ON CARDIAC REMODELING AND PERIVASCULAR INFLAMMATIONPrincipal Investigator
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
A possible treatment strategy for cardiovascular remodeling by metabolic syndrome-The gene therapy for use of MCP-1 7ND mutated gene-
- Principal Investigator
  
  KUWAHARA Fumitaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
NEW TREATMENT FOR PULMONAY HYPERTENSION
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
NEW TREATMENT FOR DIASTOLIC DYSFUNCTION BY PREVENTING CARDIAC FIBROSIS -GENE THERAPY USING A MUTANT TGF-β, RECEPTOR-Principal Investigator
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
PREVENTION OF VASCULAR REMODELING BY INHIBITING EARLY INFLAMMATORY PROCESS - GENE THERAPY USING A MUTANT INTERFERON-GAMMA RECEPTOR GENE -
- Principal Investigator
  
  SEKI Yukihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
移植後冠動脈硬化に対する抗炎症性サイトカイン療法の試み
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Prevention of Cardiac9 Remodeling and Diastolic Dysfunction by inhibiting Fibrotic Process.
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Fukuoka University
Novel anti-MCP-1 gene therapy against restenosis and atherosclerosis
- Principal Investigator
  
  EGASHIRA Kensuke
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Physiological function and Molecular mechanism of regulation by the CIS/JAB family members
- Principal Investigator
  
  YOSHIMURA Akihkio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional biochemistry
- Research Institution
  Kurume University
血管平滑筋細胞増殖における低分子量G蛋白質RhoAによるPLD活性化Principal Investigator
- Principal Investigator
  
  甲斐久史
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
アンジオテンシンIIによる細胞増殖・肥大におけるGRK-5抑制効果の検討Principal Investigator
- Principal Investigator
  
  甲斐久史
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University

[Journal Article] Angiotensin II receptor blocker and statin combination therapy associated with higher skeletal muscle index in patients with cardiovascular disease: A retrospective study.2022
- Author(s)
  Harada H, Niiyama H, Katoh A, Kai H.
- Journal Title
  
  J Clin Pharmacy Ther.
  
  Volume: 47 Pages: 89-96
- DOI
  10.1111/jcpt.13540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies2021
- Author(s)
  Kai Hisashi、Kai Mamiko、Niiyama Hiroshi、Okina Norihito、Sasaki Motoki、Maeda Takanobu、Katoh Atsushi
- Journal Title
  
  Hypertension Research
  
  Volume: 44 Pages: 955-968
- DOI
  10.1038/s41440-021-00641-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Low blood pressure and cardiovascular events in diabetic patients with coronary artery disease after revascularization: The CREDO-Kyoto Registry Cohort-1.2020
- Author(s)
  Kai H, Katoh A, Harada H, Niiyama H, Furukawa Y, Kimura T.
- Journal Title
  
  Hypertens Res
  
  Volume: 43 Pages: 715-723
- DOI
  10.1038/s41440-020-0407-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Increased arterial stiffness is an independent factor related to skeletal muscle mass reduction and tissue damage in patients with cardiovascular disease.2020
- Author(s)
  Harada H、Ikeda H、Nishiyama Y、Niiyama H、Katoh A、Kai H
- Journal Title
  
  Hypertens Res
  
  Volume: 43 Pages: 534-542
- DOI
  10.1038/s41440-020-0404-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Interactions of coronaviruses with ACE 2, angiotensin II, and RAS Inhibitors. Lessons from available evidence and Insights into COVID-192020
- Author(s)
  Kai H, Kai M.
- Journal Title
  
  Hypertens Res
  
  Volume: 43 Pages: 648-654
- DOI
  10.1038/s41440-020-0455-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Long-chain fatty acids in sarcopenia patients with cardiovascular diseases importance of n-9 monounsaturated fatty acids.2020
- Author(s)
  Katoh A, Ikeda H, Matsushima Y, Sasaki M, Okina N, Niiyama H, Nishiyama Y, Kai H.
- Journal Title
  
  JCSM Clinical Reports
  
  Volume: 5 Pages: 121-128
- DOI
  10.1002/crt2.27
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Incidence of Peri-Operative Pulmonary Thromboembolism in Kurume2020
- Author(s)
  Kumagai E, Adachi H, Kai H, Shimada T, Okina N, Shihara M, Hirai Y, Ohtsubo H, Ouchida M, Matusmoto T, Onitsuka I, Fukumoto Y.
- Journal Title
  
  Kurume Med. J.
  
  Volume: 66 Issue: 1 Pages: 49-52
- DOI
  10.2739/kurumemedj.ms661006
  10.2739/kurumemedj.MS661006
- NAID
  130007867227
- ISSN
  0023-5679, 1881-2090
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Random Skin Biopsy in Patient With Rapidly Progressive Exertional Dyspnea2020
- Author(s)
  Kai H、Hamamura H、Niiyama H、Katoh A、Mouri F、Nagafuji K、Ohshima K、Yamaguchi R、Mukohara K
- Journal Title
  
  Circ Rep
  
  Volume: 2 Issue: 1 Pages: 69-70
- DOI
  10.1253/circrep.cr-19-0120
  10.1253/circrep.CR-19-0120
- NAID
  130007784349
- ISSN
  2434-0790
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08503
[Journal Article] Angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers in hypertensive patients with myocardial infarction or heart failure: a systematic review and meta-analysis2019
- Author(s)
  Ohtsubo T、Shibata R、Kai H、Okamoto R、Kumagai E、Kawano H、Fujiwara A、Kitazono T、Murohara T、Hisatomi A
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Pages: 641-649
- DOI
  10.1038/s41440-018-0167-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468, KAKENHI-PROJECT-19K08503, KAKENHI-PROJECT-17K09572
[Journal Article] Effects of lowering diastolic blood pressure to <80 mmHg on cardiovascular mortality and events in patients with coronary artery disease: a systematic review and meta-analysis2019
- Author(s)
  Okamoto R、Kumagai E、Kai H、Shibata R、Ohtsubo T、Kawano H、Fujiwara A、Ito M、Fukumoto Y、Hisatomi A
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Pages: 650-659
- DOI
  10.1038/s41440-018-0189-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468, KAKENHI-PROJECT-19K08503
[Journal Article] Effects of blood pressure lowering in patients with heart failure with preserved ejection fraction: a systematic review and meta-analysis2019
- Author(s)
  Kawano H、Fujiwara A、Kai H、Kumagai E、Okamoto R、Shibata R、Ohtsubo T、Tamura K、Maemura K、Hisatomi A
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Pages: 504-513
- DOI
  10.1038/s41440-019-0216-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468, KAKENHI-PROJECT-19K08503, KAKENHI-PROJECT-17K09592
[Journal Article] 血圧変動の臓器障害メカニズム2018
- Author(s)
  甲斐久史、山路和伯、柴田　怜
- Journal Title
  
  血圧
  
  Volume: 25 Pages: 188-193
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] 心血管疾患（脳卒中・冠動脈疾患）合併例の診療2018
- Author(s)
  甲斐久史、吉村晴美、翁長春貴、力武美子
- Journal Title
  
  日本臨牀
  
  Volume: 76 Pages: 1333-1339
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] Losartan/Hydrochlorothiazide combination is safe and effective for morning hypertension in very elderly patients.2018
- Author(s)
  Uchiwa H, Kai H, Iwamoto Y, Anegawa T, Kajimoto H, Fukuda K, Imaizumi T, Fukumoto Y.
- Journal Title
  
  Clin Exp Hypertens
  
  Volume: 40 Pages: 267-273
- DOI
  10.1080/10641963.2017.1368536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] New diagnostic index for sarcopenia in patients with cardiovascular diseases.2017
- Author(s)
  Harada H, Kai H, Shibata R, Niiyama H, Nishiyama Y, Murohara T, Yoshida N, Katoh A, Ikeda H.
- Journal Title
  
  Plos One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0178123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] Cerebral microbleeds in coronary artery disease patients during antiplatelet therapy.2017
- Author(s)
  Iwamoto Y, Kai H, Fukuda K, Uchiwa H, Anegawa T, Aoki Y, Kajimoto H, Uchiyamae Y, Abe T, Imaizumi T, Fukumoto Y.
- Journal Title
  
  Int J Cardiovasc Res
  
  Volume: 6 Pages: 1000329-1000329
- DOI
  10.4172/2324-8602.1000329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] Effectiveness of cardiac rehabilitation for prevention and treatment of sarcopenia in patients with cardiovascular disease - A retrospective cross-sectional analysis2017
- Author(s)
  Harada H, Kai H, Niiyama H, Nishiyama Y, Katoh A, Yoshida N, Fukumoto Y, Ikeda H.
- Journal Title
  
  J Nutr Health Aging
  
  Volume: 21 Pages: 449-456
- DOI
  10.1007/s12603-016-0743-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] Oral Administration of Glucosamine Improves Vascular Endothelial Function by Modulating Intracellular Redox State2017
- Author(s)
  Katoh A, Kai H, Harada H, Niiyama H, Ikesa H.
- Journal Title
  
  International Heart Journal
  
  Volume: 58 Issue: 6 Pages: 926-932
- DOI
  10.1536/ihj.16-534
- NAID
  130006251741
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] Impact of systolic blood pressure on hemorrhagic stroke in patients with coronary artery disease during anti-platelet therapy: The Japanese Coronary Artery Disease (JCAD) Study.2016
- Author(s)
  Kai H, Kohro T, Fukuda K, Yamazaki T, Nagai R.
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 224 Pages: 112-113
- DOI
  10.1016/j.ijcard.2016.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09468
[Journal Article] Impact of Low Diastolic Blood Pressure on Risk of Cardiovascular Death in Elderly Patients With Coronary Artery Disease After Revascularization　– The CREDO-Kyoto Registry Cohort-1 –2016
- Author(s)
  Kai H, Kimura T, Fukuda K, Fukumoto Y, Kakuma T, Furukawa Y; CREDO-Kyoto Investigators.
- Journal Title
  
  Circulation Journal
  
  Volume: 25 Issue: 5 Pages: 1232-1241
- DOI
  10.1253/circj.cj-15-1151
  10.1253/circj.CJ-15-1151
- NAID
  130005147673
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-16K09468
[Journal Article] 「バイオマーカーと臓器障害」血圧変動と臓器障害2015
- Author(s)
  甲斐久史
- Journal Title
  
  循環器Plus
  
  Volume: 15 Pages: 10-12
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Day-by-day blood pressure variability and functional outcome after acute ischemic stroke: Fukuoka Stroke Registry.2015
- Author(s)
  Fukuda K, Kai H, Kamouchi M, Hata J, Ago T, Nakane H, Imaizumi T, Kitazono T
- Journal Title
  
  Stroke
  
  Volume: 46 Pages: 1832-1839
- DOI
  10.1161/strokeaha.115.009076
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460756, KAKENHI-PROJECT-26461301, KAKENHI-PROJECT-26293158
[Journal Article] BMP type I receptor inhibition attenuates endothelial dysfunction in mice with chronic kidney disease.2015
- Author(s)
  Kajimoto, H. Kai, H. Aoki, H. Uchiwa, H. Aoki, Y. Yasuoka, S. Anegawa, T. Mishina, Y. Suzuki, A. Fukumoto, Y. Imaizumi, T.
- Journal Title
  
  Kidney International
  
  Volume: 87 Pages: 128-136
- DOI
  10.1038/ki.2014.223
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24591104, KAKENHI-PROJECT-26670621, KAKENHI-PROJECT-25461140
[Journal Article] Benefit of losartan/hydrochlorthizide-fixed dose combination treatment for isolated morning hypertension: the MAPPY study2015
- Author(s)
  Kai H, Ueda T, Uchiwa H, Iwamoto Y, Anegawa T, Fukuda K, Fukumoto Y, Imaizumi T.
- Journal Title
  
  Clinical and Experimental Hypertension
  
  Volume: ePub Pages: 1-9
- DOI
  10.3109/10641963.2015.1013118
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Large Blood Pressure Variability Aggravates Arteriolosclerosis and Cortical Sclerotic Changes in the Kidney in Hypertensive Rats2014
- Author(s)
  Aoki Y, Kai H, Kajimoto H, Kudo H, Takayama N, Yasuoka S, Anegawa T, Iwamoto Y, Uchiwa H, Fukuda K, Kage M, Kato S, Fukumoto Y, Imaizumi T.
- Journal Title
  
  Circulation Journal
  
  Volume: 78 Issue: 9 Pages: 2284-2291
- DOI
  10.1253/circj.cj-14-0027
  10.1253/circj.CJ-14-0027
- NAID
  130004677614
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590462, KAKENHI-PROJECT-24591104, KAKENHI-PROJECT-25461140
[Journal Article] 血圧変動による臓器障害の機序：RASの関与2014
- Author(s)
  甲斐久史
- Journal Title
  
  Angiotensin Research
  
  Volume: 11 Pages: 144-149
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Molecular mechanism of aggravation of hypertensive organ damages by short-term blood pressure variability.2014
- Author(s)
  Kai H, Kudo H, Takayama N, Yasuoka S, Aoki Y, Imaizumi T.
- Journal Title
  
  Current Hypertension Reviews
  
  Volume: 10 Pages: 125-133
- DOI
  10.2174/1573402111666141217112655
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Respiratory variation of vertebral arterial flow in a patient scheduled for coronary artery bypass graft surgery - Lesson from atypical subclavian steel phenomenon -2013
- Author(s)
  Anegawa T, Kai H, Fukuda K, Iwamoto Y, Tsuru T, Itaya N, Koiwaya H, Takeuchi T, Toyama Y, Oba T, Mawatari K, Takeuchi Y, Morioka M, Tanaka H, Ueno T, Imaizumi T
- Journal Title
  
  Circulation Journal
  
  Volume: 77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Report of the Salt Reduction Committee of the Japanese Society of Hypertension(1) Role of salt in hypertension and cardiovascular diseases.2013
- Author(s)
  Ando K, Kawarazaki H, Miura K, Matsuura H, Watanabe Y, Yoshita K, Kawamura M, Kusaka M, Kai H, Tsuchihashi T, Kawano Y.
- Journal Title
  
  Hypertension Research
  
  Volume: 36 Pages: 1009-1019
- DOI
  10.1038/hr.2013.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Report of the Salt Reduction Committee of the Japanese Society of Hypertension(2) Goal and strategies of dietary salt reduction in the management of hypertension.2013
- Author(s)
  Miura K, Ando K, Tsuchihashi T, Yoshita K, Watanabe Y, Kawarazaki H, Matsuura H, Kusaka M, Kai H, Kawamura M, Kawano Y.
- Journal Title
  
  Hypertension Research
  
  Volume: 36 Pages: 1020-1025
- DOI
  10.1038/hr.2013.105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] 血圧変動と臓器障害2013
- Author(s)
  甲斐久史
- Journal Title
  
  Annual Review循環器2013
  
  Volume: N/A Pages: 193-201
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] 二次予防としての血圧管理2013
- Author(s)
  青木裕司、岩元美子、打和大幹、甲斐久史
- Journal Title
  
  Cardiac Practice
  
  Volume: 24 Pages: 139-144
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] マイクロコンベックス型探触子を用いた経口腔頚部血管超音波検査法(modifiedTOCU)2013
- Author(s)
  姉川敬裕、甲斐久史、梶本英美、安岡逸
- Journal Title
  
  脳卒中
  
  Volume: 35(1) Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590565
[Journal Article] Report of the Salt Reduction Committee of the Japanese Society of Hypertension (3) Assessment and application of salt intake in the management of hypertension.2013
- Author(s)
  Tsuchihashi T, Kai H, Kusaka M, et al.
- Journal Title
  
  Hypertension Research
  
  Volume: 36 Pages: 1026-1031
- DOI
  10.1038/hr.2013.103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500884, KAKENHI-PROJECT-24591104
[Journal Article] Reduction in Morning Blood Pressure Is a Key Factor for Ameliorating Urinary Albumin Excretion in Patients With Morning Hypertension Irrespective of Treatment Regimen2013
- Author(s)
  Kai H, Kaneyuki M, Shihara M, Toyama Y, Mitsutake Y, Umei H, Kusaba K, Ueda T, Adachi H, Imaizumi T
- Journal Title
  
  Circulation Journal
  
  Volume: 77 Issue: 6 Pages: 1551-1557
- DOI
  10.1253/circj.cj-12-1102
  10.1253/circj.CJ-12-1102
- NAID
  10031158886
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Blood Pressure Variability Activates Cardiac Mineralocorticoid Receptor and Induces Cardiac Remodeling in Hypertensive Rats2013
- Author(s)
  Yasuoka S, Kai H, Kajimoto H, Anegawa T
- Journal Title
  
  Circulation Journal
  
  Volume: 77 Issue: 6 Pages: 1474-1481
- DOI
  10.1253/circj.cj-12-1253
  10.1253/circj.CJ-12-1253
- NAID
  10031158877
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-24591104
[Journal Article] マイクロコンベックス型探触子を用いた経口腔頚部血管超音波検査法（modified TOCU）2013
- Author(s)
  1. 姉川敬裕、福田賢治、甲斐久史、崎間洋邦、矢坂正弘、梶本英美、岩元美子、安岡逸、青木裕司、打和大幹、岡田靖、今泉勉
- Journal Title
  
  脳卒中
  
  Volume: 35 Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] High-sensitive troponin T is associated with atrial fibrillation in a general population2012
- Author(s)
  Anegawa T, Kai H, (他11名2番目)
- Journal Title
  
  Int J Cardiol
  
  Volume: 156 Pages: 98-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Losartan/hydrochlorothiazide combination versus high dose losartan in patients with morning hypertension - A prospective, randomized, open-labeled, parallel-group, multicenter trial -2012
- Author(s)
  Ueda T, Kai H, Imaizumi T
- Journal Title
  
  Hypertension Research
  
  Volume: 35 Pages: 708-712
- DOI
  10.1038/hr.2012.27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure : new effect of asymmetric dimethylarginine2012
- Author(s)
  Kajimoto H, Kai H, 他7名2番目
- Journal Title
  
  Kidney International
  
  Volume: 81 Pages: 762-768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Stent-anchored coil embolotherapy; Novel treatment procedure for huge pulmonary arterio-venous malformation in hereditary hemorrhagic telangiectasia-2012
- Author(s)
  Koiwaya H, Kai H, Ueno T, Niiyama H, Takeuchi T, Ueda S-I, Gondo T, Kumagai E, Miyamoto M, Yokoyama S, Sasaki K-I, Toyama Y, Ohtsuka M, Mitsutake Y, Anegawa T, Suda K, Imaizumi T
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 157 Pages: 122-124
- DOI
  10.1016/j.ijcard.2012.03.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] Stent-anchored coil embolotherapy. Novel treatment procedure for huge pulmonary arterio-venous malformation in hereditary hemorrhagic telangiectasia2012
- Author(s)
  Koiwaya H, Kai H, Anegawa T, (他14名2番目)
- Journal Title
  
  Int J Cardiol
  
  Volume: 157(1) Pages: 122-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure : new effect of asymmetric dimethylarginine2012
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Anegawa T, (他5名2番目)
- Journal Title
  
  Kidney Int
  
  Volume: 81 Pages: 762-768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Is low diastolic blood pressure an independent risk for cardiovascular events in patients with manifest atherosclerotic disease?2012
- Author(s)
  Kai H, Ueno T, Kimura T, Adachi H, Imaizumi T
- Journal Title
  
  Hypertension
  
  Volume: 59
- DOI
  10.1161/hypertensionaha.111.190264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591104
[Journal Article] High-sensitive troponin T is associated with atrial fibrillation in a general population2012
- Author(s)
  Anegawa T, Kai H, Kajimoto H, YasuokaS
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 156 Pages: 98-100
- DOI
  10.1016/j.ijcard.2011.12.117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22791042, KAKENHI-PROJECT-24790597
[Journal Article] Selective gene expression analysis of muscular and vascular components in hearts using laser microdissection method2012
- Author(s)
  Ikeda A, Kai H, Kajimoto H, Yasuoka S
- Journal Title
  
  International Journal of Vascular Medicine
  
  Volume: Article ID 863410 Pages: 2012-2012
- DOI
  10.1155/2012/863410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22791042, KAKENHI-PROJECT-24591104
[Journal Article] Losartan/hydrochlorothiazide combination versus high dose losartan in patients with morning hypertension-A prospective, randomized, open-labeled, parallel-group, multicenter trial2012
- Author(s)
  Ueda T, Kai H, Imaizumi T
- Journal Title
  
  Hypertens Res online publication
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure: new effect of asymmetric dimethylarginine.2012
- Author(s)
  Kajimoto H, Kai H, Imaizumi T(他6人9番目)
- Journal Title
  
  Kidney Int
  
  Volume: 81 Pages: 762-768
- DOI
  10.1038/ki.2011.476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22590903, KAKENHI-PROJECT-22791042, KAKENHI-PROJECT-23591210, KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24659640
[Journal Article] Enhanced cardiac inflammation and fibrosis inovariectomized hypertensive rats -A possible mechanism of diastolic dysfunction in postmenopausal women-2011
- Author(s)
  Mori T, Kai H, Kajimoto H, Yasuoka S, Anegawa T
- Journal Title
  
  Hypertens Res
  
  Volume: 34[Epub ahead of print] Pages: 496-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590565
[Journal Article] Enhanced cardiac inflammation and fibrosis in ovariectomized hypertensive rats : a possible mechanism of diastolic dysfunction in postmenopausal women2011
- Author(s)
  Mori T, Kai H, Imaizumi T(他7人10番目)
- Journal Title
  
  Hypertena Research
  
  Volume: 34 Pages: 496-502
- DOI
  10.1038/hr.2010.261
- NAID
  10031163207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-21590943, KAKENHI-PROJECT-22590565
[Journal Article] Simvastatin prevents large blood pressure variability-induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways2011
- Author(s)
  Takayama N, Kai H, Yasuoka S, Anegawa T, Kajimoto H, (他4名2番目)
- Journal Title
  
  Hypertens Res
  
  Volume: 34 Pages: 341-347
- NAID
  10031163179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Simvastatin prevents large blood pressure variability-induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways.2011
- Author(s)
  Takayama N, Kai H, Yasuoka S, AnegawaT, Kajimoto H
- Journal Title
  
  Hypertens Res
  
  Volume: 34 Pages: 341-347
- NAID
  10031163179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590565
[Journal Article] Simvastatin prevents large blood pressure variability-induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways2011
- Author(s)
  Takayama N, Kai H, Imaizumi T(他7人10番目)
- Journal Title
  
  Hypertension Research
  
  Volume: 34 Pages: 341-347
- DOI
  10.1038/hr.2010.229
- NAID
  10031163179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-21590943, KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22791042
[Journal Article] Enhanced cardiac inflammation and fibrosis in ovariectomized hypertensive rats-A possible mechanism of diastolic dysfunction in postmenopausal women-2011
- Author(s)
  Mori T, Kai H, Kajimoto H, Ikeda A, Yasuoka S, Anegawa T, (他5名2番目)
- Journal Title
  
  Hypertens Res
  
  Volume: 34 Pages: 496-502
- NAID
  10031163207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Longest survivor of pulmonary atresia with ventricular septal defect-well-developed major aortopulmonary collateral arteries demonstrated by multidetector computed tomography2011
- Author(s)
  Fukui D, Kai H, Imaizumi T(他9人12番目)
- Journal Title
  
  Circulation
  
  Volume: 124 Pages: 2155-2157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Low diastolic blood pressure may not be an independent risk for cardiovascular death in revascularized coronary artery disease patients2011
- Author(s)
  Kai H, (他6名1番目)
- Journal Title
  
  J Hypertens
  
  Volume: 29(10) Pages: 1889-1896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Low DBP may not be an independent risk for cardiovascular death in revascularized coronary artery disease patients2011
- Author(s)
  Kai H, Imaizumi T(他5人7番目)
- Journal Title
  
  J Hypertens
  
  Volume: 29 Pages: 1889-1896
- DOI
  10.1097/hjh.0b013e32834a5a67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Reduction and activation of circulating dendritic cells in patients with decompensated heart failure2011
- Author(s)
  Sugi Y, Kai H, (他9名3番目)
- Journal Title
  
  Int J Cardiol
  
  Volume: 147(2) Pages: 258-264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Longest survivor of pulmonary atresia with ventricular septal defect : well-developed major aortopulmonary collateral arteries demonstrated by multidetector computed tomography2011
- Author(s)
  Fukui D, Kai H, 他10名2番目
- Journal Title
  
  Circulation
  
  Volume: 124 Pages: 2155-2157
- DOI
  10.1161/circulationaha.111.035469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension in rats.2010
- Author(s)
  Sugi Y, Kai H, 他4名3番目
- Journal Title
  
  Basic Research in Cardiology
  
  Volume: 105 Pages: 409-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension in rats2010
- Author(s)
  Takemiya K, Kai H, (他4名2番目)
- Journal Title
  
  Basic Res Cardiol
  
  Volume: 105 Pages: 409-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Autologous transplantation of bone marrow mononuclear cells improved ischemic peripheral neuropathy in humans2010
- Author(s)
  Arima K, Kai H, Imaizumi T(他8人11番目)
- Journal Title
  
  J Am Coll Cardiol
  
  Volume: 56 Pages: 238-239
- DOI
  10.1016/j.jacc.2010.02.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension in rats2010
- Author(s)
  Takemiya K, Kai H, (他4名2番目)
- Journal Title
  
  Basic Research in Cardiology 105
  
  Pages: 409-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Autologous Transplantation of Bone Marrow Mononuclear Cells Improved Ischemic Peripheral Neuropathy in Humans2010
- Author(s)
  Arima K, Kai H, (他9名9番目)
- Journal Title
  
  J Am Coll Cardiol
  
  Volume: 56(3) Pages: 238-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Inhibition of pigment epithelium-derived factor(PEDF) augments vascular endothelial growth factor(VEGF)-induced recovery of limb perfusion after ischemia in Klitho mouse2010
- Author(s)
  Arima K, Kai H, (他8名8番目)
- Journal Title
  
  Lett Drug Des Discov
  
  Volume: 7(7) Pages: 541-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats2010
- Author(s)
  Takemiya K, Kai H, Imaizumi T(他3人6番目)
- Journal Title
  
  Basic Res Cardiol
  
  Volume: 105 Pages: 409-417
- DOI
  10.1007/s00395-009-0065-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Autologous Transplantation of Bone Marrow Mononuclear Cells Improved Ischemic Peripheral Neuropathy in Humans.2010
- Author(s)
  Arima K, Kai H, 他9名10番目
- Journal Title
  
  Journal of American College of Cardiology
  
  Volume: 56 Pages: 238-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] 慢性腎不全患者の心血管病変進展における内因性NO 合成阻害物質(ADMA)の役割2009
- Author(s)
  梶本英美、甲斐久史、今泉勉
- Journal Title
  
  腎臓 32
  
  Pages: 103-107
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation2009
- Author(s)
  Kudo H, Kai H, (他11名2番目)
- Journal Title
  
  Hypertension 54
  
  Pages: 832-838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] 慢性腎不全患者の心血管病変進展における内因性NO合成阻害物質(ADMA)の役割2009
- Author(s)
  梶本英美、甲斐久史、今泉勉
- Journal Title
  
  腎臓
  
  Volume: 32 Pages: 103-107
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation2009
- Author(s)
  Kudo H, Kai H, Kajimoto H, Ikeda A, Yasuoka S, Anegawa T, (他7名2番目)
- Journal Title
  
  Hypertension
  
  Volume: 54 Pages: 832-838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation2009
- Author(s)
  Kudo H, Kai H, Imaizumi T(他10人13番目)
- Journal Title
  
  Hypertension
  
  Volume: 54 Pages: 832-838
- DOI
  10.1161/hypertensionaha.109.135905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Reduction and activation of circulating dendritic cells in patients with decompensated heart failure2009
- Author(s)
  Sugi Y, Kai H, (他4名3番目)
- Journal Title
  
  Int J Cardiol (Online)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] 高用量ストロングスタチン服用を必要とする難治性高LDLコレステロール血症に対するエゼチミブ隔日投与併用療法の有用性2008
- Author(s)
  甲斐久史, 今泉勉
- Journal Title
  
  Prog Med 28
  
  Pages: 159-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Usefulness of high concentration calcium chloride solution for correction of activated partial thromboplastin time (APTT) in patients with high hematocrit value.2008
- Author(s)
  Kanahara M, Kai H, 他5名2番目
- Journal Title
  
  Thromb Res 121
  
  Pages: 781-785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] 治療抵抗性高LDLコレステロール血症に対するアプローチ2008
- Author(s)
  甲斐久史
- Journal Title
  
  Med Pract 25
  
  Pages: 536-536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] 高用量ストロングスタチン服用を必要とする難治性高LDL コレステロール血症に対するエゼチミブ隔日投与併用療法の有用性2008
- Author(s)
  甲斐久史, 今泉勉
- Journal Title
  
  Progress in Medicine 28(1)
  
  Pages: 159-163
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Mutant MCP-1 therapy inhibits tumor angiogenesis and growth of malignant melanoma in mice.2008
- Author(s)
  Koga M, Kai H, 他10名2番目
- Journal Title
  
  Biochem Biophys Res Comm 365
  
  Pages: 279-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Usefulness of high concentration calcium chloride solution for correction of activated partial thromboplastin time (APTT) in patients with high hematocrit value.2008
- Author(s)
  Kanahara M, Kai H, Okamura T, Wada T, Suda K, Imaizumi T, Sagawa K
- Journal Title
  
  Thromb Res 121(6)
  
  Pages: 781-785
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] 治療抵抗性高LDL コレステロール血症に対するアプローチ2008
- Author(s)
  甲斐久史
- Journal Title
  
  Medical Practice 25(3)
  
  Pages: 536-536
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Usefulness of high concentration calcium chloride solution for correction of activated partial thromboplasstin time(APTT)in patients with high hematocrit value2008
- Author(s)
  Kanahara M, Kai H(他5名2番目)
- Journal Title
  
  Thromb Res 121
  
  Pages: 781-785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Vitamin C reversed the malfunction of peripheral blood-derived mononuclear cells in chronic smokers through the anti-oxidative property2008
- Author(s)
  Takeshita Y, Katuski Y, Katsuda Y, Kai H, Saito Y, Arima K, Sasaki K-I, Imaizumi T
- Journal Title
  
  Circ J 72(4)
  
  Pages: 654-659
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Mutant MCP-1 therapy inhibits tumor angiogenesis and growth of malignant melanoma mice2008
- Author(s)
  Koga M, Kai H(他10名2番目)
- Journal Title
  
  Biochem Biophys Res Comm 365
  
  Pages: 279-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Mutant MCP-1 Therapy Inhibits Tumor Angiogenesis and Growth of Malignant Melanoma in Mice.2008
- Author(s)
  Koga M, Kai H, Egami K, Murohara T, Ikeda A, Yasuoka S, Egashira K, Matsuishi T, Kai M, Kataoka Y, Kuwano M, Imaizumi T
- Journal Title
  
  Biochem Biophys Res Comm 365(2)
  
  Pages: 279-284
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Long-term treatment with valsartan improved cyclic variation of the myocardial integral backscatter signal and diastolic dysfunction in hypertensive patients-The echorcardiographic assessment-2008
- Author(s)
  Mizuta M, Kai H, 他6名2番目
- Journal Title
  
  Hypertens Res 31
  
  Pages: 1843-1849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Long-term treatment with valsartan improved cyclic variation of the myocardial integral backscatter signal and diastolic dysfunction in hypertensive patients -The echorcardiographic assessment-2008
- Author(s)
  Mizuta Y, Kai H, Mizoguchi M, Osada K, Tahara N, Nakaura H, Kuwahara F, Imaizumi T
- Journal Title
  
  Hypertens Res 31(10)
  
  Pages: 1843-1849
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Reply to a letter to the Editor. Simvastatin attenuates plaque inflammation. -Evaluation by fluorodeoxyglucose positron emission tomography.2007
- Author(s)
  Kai H, Tahara N, Ishibashi M, Imaizumi T
- Journal Title
  
  J Am Coll Cardiol 49(19)
  
  Pages: 1991-1992
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Inhibition of intrinsic interferon-γ function prevents neointima formation after vascular injury.2007
- Author(s)
  Kusaba K, Kai H, Koga M, Takayama N, Ikeda A, Yasukawa H, Seki Y, Egashira K, Imaizumi T
- Journal Title
  
  Hypertension 49(4)
  
  Pages: 909-915
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Inhibition of progression and stabilization of plaques by postnatal interferon-γ function blocking in ApoE-KO mice.2007
- Author(s)
  Koga M, Kai H, Yasukawa H, Yamamoto T, Kato S, Kusaba K, Kai M, Egashira K, Kataoka T, Imaizumi T
- Journal Title
  
  Circ Res 101(4)
  
  Pages: 348-356
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Atherosclerosis plaque formation was prevented by postnatal blocking of interferon-γ function in AdoE-KO mice.2007
- Author(s)
  Koga M, Kai H(他9人2番目)
- Journal Title
  
  Hypertens Res 30 (3)
  
  Pages: 259-267
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] The Prevalence of inflammation in carotid atherosclerosis. First prospective analysis with fluorodeoxyglucose positron emission tomography and carotid ultrasonography2007
- Author(s)
  Tahara N, Kai H, Nakaura H, Ishibashi M, Hayabuchi N, Imaizumi T
- Journal Title
  
  Eur Heart J 28(18)
  
  Pages: 2243-2248
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Soluble interferon-gamma receptors prevent neointima formation after vascular injury2007
- Author(s)
  Kusaba K, Kai H(他6名2番目)
- Journal Title
  
  Hypertension 49(4)
  
  Pages: 909-915
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Inhibition of progression and stabilization of plaques by therapeutic interferon-γ function blocking in ApoE-KO mice.2007
- Author(s)
  Koga M, Kai H(他9人2番目)
- Journal Title
  
  Circulation Research 100(online)
  
  Pages: 20070510-20070510
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Characteristic features of QRST integral mapping in patients with high-risk Brugada syndrome.2007
- Author(s)
  Kanahara M, Kai H(他5名2番目)
- Journal Title
  
  Circ J 71(1)
  
  Pages: 63-69
- NAID
  110006151866
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] The prevalence of inflammation in carotid atherosclerosis-First prospective analysis with fluorodeoxyglucose positron emission tomography and carotid ultrasonoraphy2007
- Author(s)
  Tahara N, Kai H(他4名2番目)
- Journal Title
  
  Eur Heart J 28
  
  Pages: 2243-2248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Ihhibition of progression and stabihzation of plaques by postnatal interferon-γ function blocking in ApoE-KO mice2007
- Author(s)
  Koga M, Kai H(他9名2番目)
- Journal Title
  
  Circulation Research 101
  
  Pages: 348-356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Soluble interferon-γ receptors prevent neointima formation after vascular injury.2007
- Author(s)
  Kusaba K, Kai H, et al.
- Journal Title
  
  Hypertension 49 (4)
  
  Pages: 909-915
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Inhibition of intrinsic interferon-γ function prevents neointima formation after vascular iniury2007
- Author(s)
  Kusaba K, Kai H(他7名2番目)
- Journal Title
  
  Hypertension 49
  
  Pages: 909-915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Postnatal blocking of interferon-g function prevented atherosclerotic plaque formation in apolipoprotein E-knockout mice2007
- Author(s)
  Koga M, Kai H(他10名2番目)
- Journal Title
  
  Hypertens Res 30(3)
  
  Pages: 259-267
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is strongly associated with the metabolic syndrome.2007
- Author(s)
  Tahara N, Kai H, Yamagishi S, Mizoguchi M, Nakaura H, Ishibashi M, Kaida H, Baba K, Hayabuchi N, Imaizumi T
- Journal Title
  
  J Am Coll Cardiol 49(14)
  
  Pages: 1533-1539
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is strongly associated with the metabolic syndrome2007
- Author(s)
  Tahara N, Kai H(他8名2番目)
- Journal Title
  
  J Am Coll Cardiol 49
  
  Pages: 1533-1539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Inhibition of progression and stabilization of plaques by therapeutic interferon-γ function blocking in ApoE-KO mice.2007
- Author(s)
  Koga M, Kai H, et al.
- Journal Title
  
  Circ Res 2007
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Atherosclerotic plaque formation was prevented by postnatal blocking of interferon-γ function in apoE-knockout mice.2007
- Author(s)
  Koga M, Kai H, et al.
- Journal Title
  
  Hypertens Res 30(3)
  
  Pages: 259-267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Postnatal blocking of interferon-γ function prevented atherosclerotic plaque forrmation in apoprotein E-kockout mice2007
- Author(s)
  Koga M, Kai H(他8名10番目)
- Journal Title
  
  Hypertens Res 30
  
  Pages: 259-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Simvastatin attenuates plaque inflammation -Evaluation by fluoro- deoxyglucose positron emission tomography-2006
- Author(s)
  Tahara N, Kai H(他6名2番目)
- Journal Title
  
  J Am Coll Cardiol 48(9)
  
  Pages: 1825-1831
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Simvastatin attenuates plaque inflammation.-Evaluation by fluorodeoxyglucose positron emission tomography.2006
- Author(s)
  Tahara N, Kai H, et al.
- Journal Title
  
  J Am Coll Cardiol 48 (9)
  
  Pages: 1825-1831
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Pressure overload-induced oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II.2006
- Author(s)
  Kai H(他11名1番目)
- Journal Title
  
  Hypertens Res 29 (9)
  
  Pages: 711-718
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II.2006
- Author(s)
  Kai H, et al.
- Journal Title
  
  Hypertens Res 29 (9)
  
  Pages: 711-718
- NAID
  10019262405
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Simvastatin attenuates plaque inflammation -Evaluation by fluoro- deoxyglucose positron emission tomography-2006
- Author(s)
  Tahara N, Kai H(他6名2番目)
- Journal Title
  
  J Am Coll Cardiol 48 (9)
  
  Pages: 1825-1831
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II.2006
- Author(s)
  Kai H(他11名1番目)
- Journal Title
  
  Hypertens Res 29(9)
  
  Pages: 711-718
- NAID
  10019262405
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Perivascular inflammation and hypertensive cardiovascular remodeling.2006
- Author(s)
  Kai H(他3名1番目)
- Journal Title
  
  Curr Hypertens Rev 2(4)
  
  Pages: 263-269
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II.2006
- Author(s)
  Kai H, Mori T, Tokuda K, Takayama N, Tahara N, Takemiya K, Kubo H, Sugi Y, Fukai D, Yasukawa H, Kumahara F, Imaizumi T
- Journal Title
  
  Hypertens Res 29
  
  Pages: 711-718
- NAID
  10019262405
- Data Source
  KAKENHI-PROJECT-17590769
[Journal Article] Safety and efficacy of repeated sauna bathing in patients with chronic systolic failure.2005
- Author(s)
  Miyamoto H, Kai H, (他5名, 2番目)
- Journal Title
  
  J Card Fail 11(6)
  
  Pages: 432-436
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Diastolic dysfunction in hypertensive hearts-Role of perivascular inflammation and reactive myocardial fibrosis.2005
- Author(s)
  Kai H, (他3名, 1番目)
- Journal Title
  
  Hypertens Res 28(6)
  
  Pages: 483-490
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] "Lead-tube" like aorta with intractable systolic hypertension2005
- Author(s)
  Kai H, (他2名, 1番目)
- Journal Title
  
  Clin Cardiol 28(9)
  
  Pages: 442-442
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.2004
- Author(s)
  Tokuda K, Kai H, Kuwahara F, Yasukawa H, Tahara N, Kudo H, Takemiya K, Koga M, Yamamoto T, Imaizumi T.
- Journal Title
  
  Hypertension 43(2 pt2)
  
  Pages: 499-503
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590781
[Journal Article] Soybean isoflavones eliminate nifedipine-induced flushing of tail skin in ovariectomized mice.2004
- Author(s)
  M.Kai, A.Yamauchi, K.Tominaga, A.Koga, H.Kai.Y.Kataoka
- Journal Title
  
  Journal of Pharmacological Sciences 95
  
  Pages: 476-478
- NAID
  10014165988
- Data Source
  KAKENHI-PROJECT-15590475
[Journal Article] Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscle attenuates monocrotaline -induced pulmonary hypertension and prolongs survival in rats.2004
- Author(s)
  Tahara N, Kai H, Niiyama H, Mori T, Sugi Y, Takayama N, Yasukawa H, Numaguchi Y, Matsui H, Okumura K, Imaizumi T
- Journal Title
  
  Human Gene Ther 15
  
  Pages: 1270-1278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction -Another model of inflammatioin?-2004
- Author(s)
  Kuwahara F, Kai H, et al.
- Journal Title
  
  Hypertension 43(4)
  
  Pages: 739-745
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590781
[Journal Article] Repeated gene transfers of naked prostacyclin synthase plasmid into skeletal muscles attenuate monocrotaline-induced pulmonary hypertension and prolong survival in rats.2004
- Author(s)
  Tahara N, Kai H, Niiyama H, Mori T, Sugi Y, Takayama N, Yasukawa H, Numaguchi Y, Matsui H, Okamura K, Imaizumi T.
- Journal Title
  
  Human Gene Ther 15(12)
  
  Pages: 1270-1278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.2004
- Author(s)
  Tokuda K, Kai H, Kuwahara F, Yasukawa H, Tahara N, Kudo H, Takemiya K, Koga M, Yamamoto T, Imaizumi T.
- Journal Title
  
  Hypertension 43(2 pt2)
  
  Pages: 499-503
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis2004
- Author(s)
  Tokuda K, Kai H(他8名2番目)
- Journal Title
  
  Hypertension 43(2)
  
  Pages: 499-503
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction-Another model of inflammation-2004
- Author(s)
  Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, Egashira K, Imaizumi T.
- Journal Title
  
  Hypertension 43(4)
  
  Pages: 739-745
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Repeated gene transfers of naked prostacyclin synthase plasmid into skeletal muscles attenuate monocrotaline-induced pulmonary hypertension and prolong survival in rats.2004
- Author(s)
  Tahara N, Kai H(全11名2番目)
- Journal Title
  
  Human Gene Ther 15(12)
  
  Pages: 1270-1278
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Soybean isoflavones eliminate nifedipine-induced flushing of tail skin in ovariectomized mice2004
- Author(s)
  Mamiko Kai, Atsushi Yamauchi, Koji Tominaga, Ayako Koga, Hisashi Kai, Yasufumi Kataoka
- Journal Title
  
  Journal of Pharmacological Sciences 95
  
  Pages: 476-478
- NAID
  10014165988
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590475
[Journal Article] Hypertensive Myocardial Fibrosis and Diastolic Dysfunction Another Model of Inflammation?2004
- Author(s)
  Fumitaka Kuwahara, Kai H(他5名2番目)
- Journal Title
  
  Hypertension 43(4)
  
  Pages: 739-745
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction-Another model of inflammation-.2004
- Author(s)
  Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, Egashira K, Imaizumi T.
- Journal Title
  
  Hypertension 43(4)
  
  Pages: 739-745
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590781
[Journal Article] Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization..2004
- Author(s)
  Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T.
- Journal Title
  
  J Am Coll Cardiol 44(3)
  
  Pages: 661-666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Soybean isoflavones eliminate nifedipine-induced flushing of tail skin in ovariectomized mice.2004
- Author(s)
  M.Kai, A.Yamauchi, K.Tominaga, A.Koga, H.Kai, Y.Kataoka
- Journal Title
  
  Journal of Pharmacological Sciences 95
  
  Pages: 476-478
- NAID
  10014165988
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590475
[Journal Article] Roles of endogenous monocyate chemoattractant protein-1 in ischemia-induced neovascularization.2004
- Author(s)
  Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T
- Journal Title
  
  J Am Coll Cardiol 44
  
  Pages: 661-666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Inhibition of STAT3 prevents neointima formation by inhibiting proliferation and promoting apoptosis of neointimal smooth muscle cells.2003
- Author(s)
  Shibata R, Kai H, Seki Y, Kato S, Wada Y, Hanakawa Y, Hashimoto K, Yoshimura A, Imaizumi T
- Journal Title
  
  Human Gene Therapy 14
  
  Pages: 601-610
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Sub-depressor dose of angiotensin type-1 receptor blocker inhibits TGF-β-mediated perivascular fibrosis in hypertensive rat hearts.2003
- Author(s)
  Tokuda K, Kai H, Kuwahara F, Imaizumi T
- Journal Title
  
  J Cardiovasc Pharmacol 42(suppl)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Ovariectomy aggravates nifedipine-induced flushing of tail skin in mice.2003
- Author(s)
  M.Kai, K.Tominaga, K.Okimoto, A.Yamauchi, H.Kai, Y.Kataoka
- Journal Title
  
  European Journal of Pharmacology 481
  
  Pages: 79-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590475
[Journal Article] Inhibition of STAT3 prevents neointime formation by inhibiting proliferation and promoting apoptosis of neointimal smooth muscle cells.2003
- Author(s)
  Shibata R, Kai H, Seki Y, Kato S, Wada Y, Hanakawa Y, Hashimoto K, Yoshimura A, Imaizumi T.
- Journal Title
  
  Human Gene Ther 14(7)
  
  Pages: 601-610
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Ovariectomy aggravates nifedipine-induced flushing of tail skin in mice2003
- Author(s)
  Mamiko Kai, Koji Tominaga, Kisaragi Okimoto, Atsushi Yamauchi, Hisashi Kai, Yasufumi Kataoka
- Journal Title
  
  European Journal of Pharmacology 481
  
  Pages: 79-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590475
[Journal Article] Rho-kinase inhibition reduces neointima formation after vascular injury by enhancing Bax expression and apoptosis2003
- Author(s)
  Shibata R, Kai H, Seki Y, Kusaba K, Takemiya K, Koga M, Jalalidin A, Tokuda K, Tahara N, Niiyama H, Nagata T, Kuwahara F, Imaizumi T.
- Journal Title
  
  J Cardiovasc Pharmacol 42(suppl)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Apoptosis induced by inhibition of cAMP responsive element binding protein in vascular smooth muscle cells. ^*co-first author.2003
- Author(s)
  Tokunou T^*, Shibata R^*, Kai H, Ichiki T, Morisaki T, Iino N, Masuda S, Shimokawa H, Egashira K, Takeshita A.
- Journal Title
  
  Circulation 108(10)
  
  Pages: 1246-1252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] an IL-6 family cytokine, upregulates matrix metalloproteinase-9 through the MEK-ERK pathway in cultured smooth muscle cells.2003
- Author(s)
  Nagata T, Kai H, Shibata R, Koga M, Yoshimura A, Imaizumi T, Oncostatin M
- Journal Title
  
  Arterioscl Thromb Vasc Biol 23
  
  Pages: 588-593
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is strongly associated with the metabolic syndrome.
- Author(s)
  Tahara N, Kai H, et al.
- Journal Title
  
  J Am Coll Cardiol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Journal Article] Selective gene expression analysis of muscular and vascular components in hearts using laser microdissection method
- Author(s)
  Ikeda A, Kai H, Kajimoto H, Yasuoka S, (他2名2番目)
- Journal Title
  
  Int J Vasc Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590943
[Journal Article] Inhibition of Progression and Stabilization of Plaques by Postnatal Interferon-{gamma} Function Blocking in ApoE-Knockout Mice.
- Author(s)
  Koga M, Kai H et al.
- Journal Title
  
  Circ Res. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590769
[Journal Article] Estrogen withdrawal prolonged vascular inflammation and oxidative stress and aggravated diastolic function in pressureoverloaded female rats.
- Author(s)
  Mori T, Kai H, Koga M, Ikeda A, Fukui D, Yasukawa H, Kai M, Imaizumi T
- Journal Title
  
  投稿中
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II-mediated chronic inflammation
- Author(s)
  Kudo H, Kai H, Koga M, Takayama N, Mori T, Ikeda A, Yasuoka S, Kajimoto H, Mifune H, Kato S, Hirooka H, Imaizumi T
- Journal Title
  
  投稿中
- Data Source
  KAKENHI-PROJECT-19590839
[Journal Article] Vascular inflammationevaluated by [18F]-FDG PET is strongly associated with the metabolic syndrome.
- Author(s)
  Tahara N, Kai H(他8人2番目)
- Journal Title
  
  J Am Coll Cardiol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590768
[Presentation] 心血管患者における骨格筋量と内服薬剤の関連―後向きコホート研究2021
- Author(s)
  原田晴仁、福田由香、佐々木元基、翁徳仁、新山寛、加藤宏司、甲斐久史
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 久留米大学医療センターにおける高血圧・循環器病制圧と心臓リハビリテーションへの取り組み2021
- Author(s)
  加藤宏司、福田由香、佐々木基起、翁徳仁、新山寛、原田晴仁、西山安浩、古賀有里、田島陽子、塚田裕也、坂口美紀、飯田みさき、毛利聡代、甲斐久史
- Organizer
  第27回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 運動能に及ぼす脂肪酸分画の影響2021
- Author(s)
  加藤宏司、福田由香、佐々木基起、翁徳仁、新山寛、原田晴仁、西山安浩、古賀有里、田島陽子、塚田裕也、坂口美紀、飯田みさき、毛利聡代、甲斐久史
- Organizer
  第27回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 糖尿病合併冠動脈疾患における血圧低値と心血管イベント発症.2020
- Author(s)
  甲斐久史、加藤宏司、新山寛、甲斐麻美子、古川裕、木村剛．
- Organizer
  第35回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Rationales of Strict Blood Pressure Control in Patients with Cardiovascular Disease.2020
- Author(s)
  甲斐久史
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 循環器疾患患者における運動能と脂肪酸代謝の関係2020
- Author(s)
  加藤宏司、岸本迪也、古賀有里、田浦陽子、塚田裕也、坂口美紀、佐々木基起、翁徳仁、新山寛、原田晴仁、西山安浩、池田久雄、甲斐久史.
- Organizer
  第26回日本心臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Is low blood pressure an independent risk for cardiovascular events in diabetic patients with coronary artery disease after revascularization? - The CREDO-Kyoto cohort-12019
- Author(s)
  Kai H, Katoh A, Niiyama H, Harada H, Kimura T, Furukawa Y
- Organizer
  European Society of Hypertension 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 「JSH2019を極める-3」心疾患合併高血圧2019
- Author(s)
  甲斐久史
- Organizer
  第8回臨床高血圧フォーラム
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Biomarker-based index for detecting sarcopenia in patients with cardiovascular disease2019
- Author(s)
  Kai H, Harada H, Niiyama H, Katoh A
- Organizer
  European Society of Cardiology ASIA with APSC & AFC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] 皮膚生検により診断された急速に進行する労作性呼吸困難の一例2019
- Author(s)
  甲斐久史、松島慶央、佐々木基起、翁徳仁、新山寛、加藤宏司、山口倫
- Organizer
  第2回日本腫瘍循環器学会
- Data Source
  KAKENHI-PROJECT-19K08503
[Presentation] Effects of low blood pressure on cardiovascular events in diabetic patients with coronary artery disease after revascularization - The CREDO-Kyoto cohort-1.2018
- Author(s)
  Kai H, Niiyama H, Rikitake-Iwamoto, Harada H, Katoh A, Furukawa Y, Kimura T.
- Organizer
  European Society of Cardiology Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] 「Hypertension Paradoxへの挑戦」合併症を考慮した厳格な血圧管理2018
- Author(s)
  甲斐久史
- Organizer
  第41回日本高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] Effects of low blood pressure on cardiovascular events in diabetic patients with coronary artery disease after revascularization - The CREDO-Kyoto cohort-1.2018
- Author(s)
  Kai H, Kimura T, Furukawa Y
- Organizer
  86th European Atherosclerosis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] Risks of cerebral microbleeds in patients with coronary artery disease on antiplatelet therapy.2018
- Author(s)
  Rikitake-Iwamoto Y, Anegawa T, Fukuda K, Kai H.
- Organizer
  27th International Society of Hypertension Annual Scientific Meeting: Hypertension Beijing 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] The effects of ezatimibe on coronary plaque volume in patients with stable angina pectoris previously treated with statin.2017
- Author(s)
  Katoh A, Hattori Y, Yoshikawa N, Niiyama H, Harada H, Kai H, Ikeda H.
- Organizer
  European Society of Cardiology Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] 抗血栓療法新時代の降圧療法2017
- Author(s)
  甲斐久史
- Organizer
  第6回臨床高血圧フォーラム
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] シンポジウム4「心不全予防と降圧療法」降圧療法による心不全予防2017
- Author(s)
  甲斐久史
- Organizer
  第40回日本高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] Losartan/HCTZ combination therapy is safe and useful in controlling morning hypertension in very elderly patients.2017
- Author(s)
  Kai H, Uchiwa H, Iwamoto Y, Fukuda K, Imaizumi T.
- Organizer
  European Society of Hypertension and Cardiovascular Protection 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] ARB/CCB併用療法は家庭血圧日間変動抑制においてARB/HCTZ併用療法より優れているか？2017
- Author(s)
  甲斐久史、今泉勉
- Organizer
  第21回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] シンポジウム12「Post-SPRINTの日本人高血圧治療戦略」冠動脈疾患の降圧治療を再考するー拡張期血圧をどう考えるか2017
- Author(s)
  甲斐久史
- Organizer
  第41回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] Symposium 5: “Challenges to the classic paradigm of the hypertensive heart disease” Fibro-inflammatory changes during progression of systolic/diastolic dysfunction in the hypertensive heart.2016
- Author(s)
  Kai H.
- Organizer
  26th International Society of Hypertension Annual Scientific Meeting 2016: Hypertension in Seoul 2016
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-09-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] ミニシンポジウム「降圧目標を再考する」冠動脈疾患患者の降圧目標ーＪカーブ現象をどこまで考慮するか2016
- Author(s)
  甲斐久史
- Organizer
  第41回日本高血圧学会学術集会
- Place of Presentation
  仙台市
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] Eight-month antiplatelet therapy increased cerebral microbleeds in coronary artery disease patients with poor blood pressure control and severe coronary lesions.2016
- Author(s)
  Iwamoto Y, Kai H, Fykuda K, Anegawa T, Aoki Y, Uchiwa H, Imaizumi T, Fukumoto Y.
- Organizer
  European Society of Cardiology Congress 2016
- Place of Presentation
  Roma, Italia
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] シンポジウム5「高血圧治療を臓器管理に生かす」冠動脈疾患と高血圧2016
- Author(s)
  甲斐久史
- Organizer
  第64回日本心臓病学会学術集会
- Place of Presentation
  東京
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] Is ARB/CCB combination superior to ARB/HCTZ combination in day-by-day blood pressure variability reduction? A prospective randomized trial.2016
- Author(s)
  Kai H, Imaizumi T.
- Organizer
  European Society of Cardiology Congress 2016
- Place of Presentation
  Roma, Italia
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09468
[Presentation] 高齢者冠動脈疾患における拡張期血圧低値は心血管死亡の確立した危険因子か？2015
- Author(s)
  甲斐久史
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  愛媛県県民文化会館（松山市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460756
[Presentation] 血栓薬服用中の冠動脈疾患における血圧レベルが脳出血発症に及ぼす影響：JCADサブ解析2014
- Author(s)
  甲斐久史、興梠貴英、福田賢治、福本義弘、山崎力、永井良三
- Organizer
  第37回日本高血圧学会学術集会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] トピックス「血圧変動性高血圧への治療戦略」Short-term Blood Pressure Variability and Cardiovascular Damages – Clinical Aspects and Molecular Mechanism –2014
- Author(s)
  甲斐久史
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Japan-Korea Joint Symposium: “Challenges to the classic paradigm of the hypertensive heart disease” Fibro-inflammatory changes during progression of systolic/diastolic dysfunction in hypertensive heart2014
- Author(s)
  Kai H
- Organizer
  58th Korean Society of Cardiology Annual Scientific Meeting
- Place of Presentation
  Goyang, Korea
- Year and Date
  2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 血圧変動による高血圧性臓器障害増悪のメカニズムとは2014
- Author(s)
  甲斐久史
- Organizer
  第18回日本適応医学会学術集会
- Place of Presentation
  東京都千代田区
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Within-individual day-by-day blood pressure variability during subacute stage predicts functional and long-term survival outcomes in ischemic stroke patients: Fukuoka Stroke Registry.2014
- Author(s)
  Fukuda K, Kai H, Kamouchi M, Hata J, Ago T, Imaizumi T, Kitazono T
- Organizer
  European Society of Cardiology Congress 2014
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-09-01
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 心疾患合併高血圧2014
- Author(s)
  甲斐久史
- Organizer
  第3回臨床高血圧フォーラム
- Place of Presentation
  広島県広島市
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 高齢者の早朝高血圧に対するロサルタン/ヒドロクロロチアジド配合剤と高用量ロサルタンの比較-MAPPY研究サブ解析の結果より-2014
- Author(s)
  打和大幹、甲斐久史、福田賢治、上田集宣、姉川敬裕、青木裕司、岩元美子、今泉勉、福本義弘
- Organizer
  第61回日本心臓病学会学術集会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Effects of systolic blood pressure levels on risk for strokes in coronary artery disease patients receiving anti-thrombotic combination therapy: JCAD study2014
- Author(s)
  Kai H, Kohro T, Fukuda K, Fukumoto Y, Yamasaki T, Nagai R
- Organizer
  European Society of Cardiology Congress 2014
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-30
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] パネルディスカッション“血圧変動と家庭血圧、24時間血圧：最新の知見”　血圧変動と臓器障害―機序2013
- Author(s)
  甲斐久史
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] “Diabetes Controversy 4：糖尿病患者における降圧薬は？―ARB or ACE阻害薬”　糖尿病合併高血圧の治療―ACE阻害薬再考2013
- Author(s)
  甲斐久史
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Large blood pressure variability aggravates arteriolosclerosis and ischemic changes in the kidney in hypertensive rats.2013
- Author(s)
  Aoki Y, Kai H, Kajimoto H, Kudo H, Takayama N, Yasuoka S, Anegawa T, Iwamoto Y, Uchiwa H, Fukuda K, Kage M, Kato S, Fukumoto Y, Imaizumi T
- Organizer
  High Blood Pressure Research 2013 Scientific Session
- Place of Presentation
  New Orleans, La, USA
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 高血圧ラットの腎臓において血圧変動増大は細動脈硬化および虚血性病変を増加させる2013
- Author(s)
  青木裕司、甲斐久史、梶本英美、工藤博司、高山成政、安岡　逸、姉川敬裕、岩元美子、打和大幹、福田賢治、鹿毛政義、加藤誠也、福本義弘、今泉勉
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Large Blood Pressure Variability Aggravates Arteriolosclerosis and Interstitial Ischemic Changes in the Kidney in Hypertensive Rats2013
- Author(s)
  Aoki Y, Kai H, Kudo H, Takayama N, Yasuoka S, Anegawa T, Iwamoto Y, Uchiwa H, Fukuda K, Kato S, Imaizumi T
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 脳梗塞患者の急性期・亜急性期における血圧の再現性に関する検討： Fukuoka Stroke Registry（FSR）2013
- Author(s)
  福田賢治，甲斐久史，鴨打正浩，石束光司，姉川敬裕，岩元美子，中根博，今泉勉，北園孝成
- Organizer
  第2回臨床高血圧フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] BMP type I receptor inhibition reduces endothelial dysfunction and vascular osteogenic differentiation in mice with chronic kidney disease.2013
- Author(s)
  Kajimoto H, Kai H, Aoki H, Uchiwa H, Aoki Y, Iwamoto Y, Angawa T, Fukuda K, Imaizumi T
- Organizer
  American Heart Association’s Scientific Sessions 2013
- Place of Presentation
  Dallas, TX, USA
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Candesartan-based Treatment for Variability Lowering of Individual Blood Pressure and Heart Rate at Home Study: CAVALIER at HOME2013
- Author(s)
  Kai H, Imaizumi T
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Candesartan-based Treatment for Variability Lowering of Individual Blood Pressure and Heart Rate at Home Study: CAVALIER at HOME2013
- Author(s)
  Hisashi Kai
- Organizer
  日本循環器学会学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] Candesartan-based Treatment for Variability Lowering of Individual Blood Pressure and Heart Rate at Home Study: CAVALIERat HOME.2013
- Author(s)
  Kai H
- Organizer
  日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] マイクロコンベックス型探触子を用いた経口腔頸部血管超音波検査法（modified TOCU）2012
- Author(s)
  姉川敬裕、甲斐久史、福田賢治、矢坂正弘、崎間洋邦、湧川佳幸、齊藤正樹、岩元美子、田原敦子、梶本英美、安岡逸、青木裕司、打和大幹、岡田　靖、今泉　勉
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] MAPPY Study Investigators: 降圧治療による尿中アルブミン減少の規定因子は何か？―早朝高血圧患者における検討―2012
- Author(s)
  甲斐久史、上田集宣、今泉勉
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 左椎骨動脈血流波形が呼気時に逆行、吸気時に順行と呼吸性変動を示した左鎖骨下動脈盗血現象の一例2012
- Author(s)
  姉川敬裕、福田賢治、甲斐久史、岩元美子、津留智子、青木裕司、打和大幹、竹内靖治、森岡基浩、今泉　勉
- Organizer
  第37回日本脳卒中学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Inhibition of CaMKII/ERK-mediated eNOS phosphorylation impairs endothelial function in renal failure mice: New effect of asymmetric dimethylarginine2012
- Author(s)
  Kajimoto H, Kai H, Aoki H, Uchiwa H, Aoki Y, Imaizumi T
- Organizer
  第16回日本心不全学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 急性期脳梗塞患者の入院中血圧変動が予後に及ぼす影響: Fukuoka Stroke Registry(FSR)2012
- Author(s)
  福田賢治、甲斐久史、鴨打正浩、石束光司、姉川敬裕、岩元美子、中根博、今泉　勉、北園孝成
- Organizer
  第37回日本脳卒中学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 非弁膜性心房細動を有する脳梗塞患者からみたCHADS2スコア、CHA2DS2-VAScスコア2012
- Author(s)
  姉川敬裕、福田賢治、甲斐久史、岩元美子、青木裕司、打和大幹、梶本英美、矢坂正弘、岡田靖、今泉勉
- Organizer
  第36回日本心臓病学会学術集会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Exaggerated Blood Pressure Variability Aggravates Arteriolosclerosis and Interstitial Ischemic Lesions in the Kidney of Hypertensive Rats2012
- Author(s)
  Aoki Y, Kai H, Kudo H, Takayama N, Yasuoka S, Anegawa T, Iwamoto Y, Uchiwa H, Fukuda K, Kage M, Kato S, Imaizumi T
- Organizer
  第16回日本心不全学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Morning blood pressure lowering rather than treatment regimen is important for reducing urinary albumin excretion in patients with morning hypertension2012
- Author(s)
  Kai H, Ueda T, Imaizumi T
- Organizer
  The 24th Scietific Meeting of the International Society of Hypertension
- Place of Presentation
  Sydney, Austraria
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 循環器治療領域における高血圧専門医取得のメリット2012
- Author(s)
  甲斐久史
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 非弁膜性心房細動を有する脳梗塞患者からみたCHADS2スコア、CHA2DS2-VAScスコア.2012
- Author(s)
  姉川敬裕、甲斐久史、梶本英美
- Organizer
  日本心臓病学会学術集会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] 急性期脳梗塞患者の日間血圧変動と予後の関係：Fukuoka Stroke Registry（FSR）2012
- Author(s)
  福田賢治、甲斐久史、鴨打正浩、石束光司、姉川敬裕、岩元美子、中根博、北園孝成、今泉勉
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Increased phosphatase and tensin homolog plays a crucial role in endothelial dysfunction in mice with renal failure2012
- Author(s)
  Kajimoto H, Kai H, Aoki H, Uchiwa H, Aoki Y, Anegawa T, Imaizumi T
- Organizer
  American Heart Association’s Scientific Sessions 2012
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] 血圧変動増大はPAK-MR系を介して高血圧性臓器障害を助長する.2012
- Author(s)
  甲斐久史、安岡逸、梶本英美(他7名)
- Organizer
  第49回日本臨床分子医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590565
[Presentation] 血圧変動増大はPAK-MR系を介して高血圧性臓器障害を助長する2012
- Author(s)
  甲斐久史、安岡　逸、梶本英美、工藤博司、高山成政、今泉　勉
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591104
[Presentation] Inhibition of CaMKII/ERK-mediated eNOS phosphorylation by asymmetric dimethylarginine is novel molecular mechanism of endothelial dysfunction in chronic kidney disease mice2012
- Author(s)
  Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  76th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] 血圧変動増大はPAK-MR系を介して高血圧性臓器障害を助長する2012
- Author(s)
  甲斐久史
- Organizer
  第49回日本臨床分子医学会学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22590565
[Presentation] p21-activated kinase-mineralocorticoid receptor pathway aggravates cardiac inflammation and remodeling in hypertensive rats with large blood pressure variability2011
- Author(s)
  Yasuoka S, Kai H, Kajimoto H, Kudo H, Takayama N, Anegawa T, Aoki Y, Iwamoto Y, Fukuda K, Imaizumi T
- Organizer
  American Heart Association Scientific Meeting 2011
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] JCS-APCS Joint Symposium."Diastolic dysfunction" fibroinflammatory changes and diastolic dysfunction in hypertensive hypertrophied hearts-From the bench to the bedside-2011
- Author(s)
  Kai H, Imaizumi T
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Cardiac Troponin T Detectable with a Highly Sensitive Assay is Associated with Atrial Fibrillation in the General Population.2011
- Author(s)
  Anegawa T, Kai H, Kajimoto H, YasuokaS
- Organizer
  第15回日本心不全学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590565
[Presentation] Cardiac troponin T measured by a highly sensitive assay is associated with atrial fibrillation in the general population2011
- Author(s)
  Anegawa T, Kai H, 他8名2番目
- Organizer
  American Heart Association Scientific Meeting 2011
- Place of Presentation
  Orlando, FL USA
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] JCS-APCS Joint Symposium. "Diastolic Dysfunction" Fibroinflammatory Changes and Diastolic Dysfunction in Hypertensive Hypertrophied Hearts-From the Bench to the Bedside-2011
- Author(s)
  Kai H, 他1名1番目
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] on behalf of CREDO-Kyoto Investigators. Low diastolic blood pressure is not an independent risk for cardiovascular death in revascularized coronary artery disease patients ? A subanalysis CREDO-Kyoto study ?2011
- Author(s)
  Kai H, Ueno T, Kimura T, Adachi H, Furukawa Y, Kita T, Imaizumi T
- Organizer
  European Society of Cardiology Congress 2011
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Low diastolic blood pressure is not an independent risk for cardiovascular death in revascularized coronary artery disease patients2011
- Author(s)
  Kai H, Niiyama H, 他5名5番目
- Organizer
  European Society of Cardiology Congress 2011
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] p21-Activated Kinase-Mineralocorticoid Receptor Pathway Aggravates Cardiac Inflammation and Remodeling in Hypertensive Rats with Large Blood Pressure Variability.2011
- Author(s)
  Yasuoka S, Kai H, Kajimoto H, AnegawaT
- Organizer
  American Heart Association Scientific Meeting 2011
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-22590565
[Presentation] Inhibition of Mineralocorticoid Receptor Prevented the Large Blood Pressure Variability-Induced Aggravation of Perivascular Inflammation and Cardiac Remodeling in Spontaneously Hypertensive Rats2011
- Author(s)
  Yasuoka S, Kai H, 他5名2番目
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Inhibition of CaMKII-and ERK-mediated eNOS phosphorylation impairs endothelial function in renal failure rats : New effect of asymmetric dimethylarginine2011
- Author(s)
  Kajimoto H, Kai H, Aoki Y, Yasuoka S, Anegawa T, Aoki H, Imaizumi T
- Organizer
  American Heart Association Scientific Meeting 2011
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Inhibition of Mineralocorticoid Receptor Prevented the Large Blood Pressure Variability-Induced Aggravation of Perivascular Inflammation and Cardiac Remodeling in Spontaneously Hypertensive Rats.2011
- Author(s)
  Yasuoka S, Kai H, Kajimoto H, AnegawaT
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590565
[Presentation] Inhibition of CaMKII-and ERK-mediated eNOS phosphorylation impairs endothelial function in renal failure mice : New effect of asymmetric dimethylarginine2011
- Author(s)
  Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  American Heart Association's Scientific Sessions
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Inhibition of Mineralocorticoid Receptor Prevented the Large Blood Pressure Variability-Induced Aggravation of Perivascular Inflammation and Cardiac Remodeling in Spontaneously Hypertensive Rats2011
- Author(s)
  Yasuoka S, Kai H, 他5名2番目
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590565
[Presentation] パネルディスカッション「血圧変動の新たな視点」Beyond Blood Pressure Variability Lowering Effect-ARBの新たな可能性-2011
- Author(s)
  甲斐久史、今泉勉
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Inhibition of CaMKII- and ERK-mediated eNOS Phosphorylation Impairs Endothelial Function in Renal Failure Rats : New Effect of Asymmetric Dimethylarginine2011
- Author(s)
  Kajimoto H, Kai H, 他5名2番目
- Organizer
  American Heart Association Scientific Meeting 2011
- Place of Presentation
  Orlando, FL USA
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Increased circulating asymmetric dimethylarginine in chronic kidney disease mice induces endothelial dysfunction by inhibiting Ca/Calmodulin-dependent protein kinase II-eNOS signaling2010
- Author(s)
  Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  American Heart Association's Scientific Sessions
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Eplerenone prevented the large blood pressurevariability-induced aggravation of cardiac remodeling by inhibiting of perivascular inflammation in spontaneously hypertensive rats.2010
- Author(s)
  Yasuoka S, Kai
- Organizer
  European Society of CardiologyCongress 2010
- Place of Presentation
  Stockholm , Sweden
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] Low diastolic blood pressure is not an independent risk for cardiovascular death inrevascularized coronary artery disease patients.2010
- Author(s)
  Kai H, Niiyama H
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] Dimethylarginine dimethylaminohydrolase protect vascular damage in CKD mice2010
- Author(s)
  Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  American Heart Association Scientific Meeting 2010
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] エプレレノンは自然高血圧発症高血圧ラットにおいて血圧変動の増大により引き起こされる高血圧性心リモデリングを抑制する.2010
- Author(s)
  安岡逸、甲斐久史、梶本英美、姉川敬裕
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590565
[Presentation] Smad-Msx-2 Pathway Plays an Initial Role in Vascular Calcification in CKD Mice2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  第74回日本循環器学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Eplerenone Prevented the Large Blood Pressure Variability-Induced Aggravation of Hypertensive Cardiac Remodeling and Left Ventricular Dysfunction in Spontaneously Hypertensive Rats2010
- Author(s)
  安岡逸、甲斐久史、工藤博司、高山成政、梶本英美、姉川敬裕、今泉勉
- Organizer
  第14回日本心不全学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Effects of diastolic blood pressure levels on long-term prognosis in patients with stable coronary artery disease-Subanalysis of CREDO-Kyoto Registry-2010
- Author(s)
  Kai H, Ueno T, Adachi H, Kimura T, Furukawa Y, Kita T, Imaizumi T
- Organizer
  第74回日本循環器学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] 血圧変動による高血圧性臓器障害の増悪-アンジオテンシンIIの重要性-2010
- Author(s)
  工藤博司、甲斐久史、高山成政、安岡逸、今泉勉
- Organizer
  第52回日本老年医学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Eplerenone prevented the large blood pressure variability-induced aggravation of perivascular inflammation and cardiac remodeling in spontaneously hypertensive rats2010
- Author(s)
  Yasuoka S, Kai H, Kajimoto H, Kudo H, Takayama N, Anegawa T, Imaizumi T
- Organizer
  第74回日本循環器学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] 血清Asymmetric Dimethylarginineの増加が腎機能低下における血管内皮障害を起こす2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Imaizumi T
- Organizer
  47th Annual Meeting of the Japanese Society of Pediatric Cardiology and Cardiac Surgery Chiba
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Increased circulating asymmetric dimethylarginine in chronic kidney disease mice induces endothelial dysfunction by inhibiting Ca/Calmodulin-dependent protein kinase II-eNOS signaling.2010
- Author(s)
  Kajimoto H, Kai H, 他4名2番目
- Organizer
  American Heart Association Annual Meeting 2010
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Increased circulating asymmetricdimethylarginine in chronic kidney disease mice induces endothelial dysfunction by inhibiting Ca/Calmodulin-dependent protein kinase II-eNOS signaling.2010
- Author(s)
  Kajimoto H, Kai H
- Organizer
  American Heart Association Scietific Meeting2010
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-22590564
[Presentation] エプレレノンは自然発症高血圧ラットにおいて血圧変動の増大により引き起こされる高血圧性心リモデリングを抑制する2010
- Author(s)
  安岡逸、甲斐久史、工藤博司、高山成政、梶本英美、姉川敬裕、今泉勉
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Korea-Japan Joint Symposium : Clinic, Home, Ambulatory and Central BP in Hypertensive Management : Impact of large blood pressure variability on hypertensive cardiac remodeling-Lesson from animal models-2010
- Author(s)
  Kai H
- Organizer
  19th Korean Society of Hypertension Annual Congress
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Asymmetric dimethylarginine impairs endothelial function in CKD mice2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Imaizumi T
- Organizer
  ISN-Nexus Symposium 2010
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Eplerenone prevented the large blood pressure variability-induced aggravation of cardiac remodeling by inhibiting of perivascular inflammation in spontaneously hypertensive rats2010
- Author(s)
  Yasuoka S, Kai H, Kajimoto H, Kudo H, Takayama N, Anegawa T, Imaizumi T
- Organizer
  European Society of Cardiology Congress 2010
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Effects of Diastolic Blood Pressure Levels on Long-term Prognosis in Patients with Stable Coronary Artery Disease2010
- Author(s)
  Kai H, (他6名1番目)
- Organizer
  日本循環器学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Smad-Msx2 pathway plays an initial role in vascular calcification in CKD mice2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  74th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Asymmetric dimethylarginine triggers vascular dysfunction in CKD mice2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Imaizumi T
- Organizer
  Xth World Congress of the International Society for Heart Research 2010 Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] 血清Asymmetric Dimethylarginineの増加が腎不全マウスにおける内皮機能障害を起こす2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
- Organizer
  The 57th Annual Scientific Session of the Japanese College of Cardiology
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] レーザーマイクロダイセクション法による心筋構成細胞の選択的遺伝子発現解析法2009
- Author(s)
  安岡逸、甲斐久史、池田理望、梶本英美、姉川敬裕、今泉勉
- Organizer
  第13回日本心不全学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] 腎不全マウスにおける血清Asymmetric Dimethylarginineの上昇が血管内皮に与える影響2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
- Organizer
  The 32^<nd> Annual Scientific Meeting of the Japanese Society of Hypertension
- Place of Presentation
  Shiga, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Enhanced cardiac inflammation and myocardial fibrosis in ovariectomized, pressure-overloaded rats-A possible mechanism of aggravation of diastolic dysfunction in the post-menopause-2009
- Author(s)
  Mori T, Kai H, Kajimoto H, Kudo H, Takayama N, Ikeda A, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  American Heart Association Scientific Meeting 2009
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Asymmetric dimethylarginine triggers vasculo-renal interaction in CKD mice2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Anegawa T, Aoki H, Imaizumi T
- Organizer
  American Heart Association's Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Estrogen replacement attenuates vascular inflammation and prevents myocardial fibrosis and diastolic dysfunction in ovariectomised hypertensive female rats.2009
- Author(s)
  Mori T, Kai H, 他9名2番目
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] 「内皮と脈管疾患」腎-血管連関-ADMAによる内皮障害-2009
- Author(s)
  甲斐久史
- Organizer
  第50回日本脈管学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] 「心筋リモデリングの分子機構」血圧変動による高血圧心リモデリング助長のメカニズム2009
- Author(s)
  甲斐久史
- Organizer
  第13回日本心不全学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] 腎不全マウスにおける血清Asymmetric Dimethylarginineの上昇が血管内皮に与える影響2009
- Author(s)
  梶本英美、甲斐久史、安岡逸、青木浩樹、姉川敬裕、今泉勉
- Organizer
  第32回日本高血圧学会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] 血清Asymmetric dimethylarginineの増加腎不全マウスにおける内皮機能障害を起こす2009
- Author(s)
  梶本英美、甲斐久史、安岡逸、青木浩樹、今泉勉
- Organizer
  第56回日本心臓病学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Asymmetric dimethylarginine plays a triggering role in vasculo-renal interaction in CKD mice2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Anegawa T, Aoki H, Imaizumi T
- Organizer
  American Heart Association Scientific Meeting 2009
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Selective collection and comprehensive gene expression analysis of each tissue component of the heart using lase microdissection method.2009
- Author(s)
  Ikeda A, Kai H, 他4名2番目
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Asymmetric dimethylarginine is a paracrine regulator of vascular function in CKD2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
- Organizer
  The 13th Annual Scientific Meeting of the Japanese Heart Failure Society
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Asymmetric dimethylarginine plays a triggering role in vasculo-renal interaction in CKD mice2009
- Author(s)
  Kajimoto H, Kai H, (他4名2番目)
- Organizer
  American Heart Association Scientific Meeting 2009
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] 「高血圧ガイドラインと心臓病診療」虚血性心疾患2009
- Author(s)
  甲斐久史
- Organizer
  第57回日本心臓病学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] Asymmeteric dimethylarginine induces endothelial dysfunction in renal failure mice.2009
- Author(s)
  Kajimoto H, Kai H, 他4名2番日
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Asymmetric Dimethylarginineが慢性腎不全における血管機能を制御している2009
- Author(s)
  梶本英美、甲斐久史、安岡逸、青木浩樹、姉川敬裕、今泉勉
- Organizer
  第13回日本心不全学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] 「内皮と脈管疾患」腎-血管連関-ADMAによる内皮障害-2009
- Author(s)
  甲斐久史
- Organizer
  第50回日本脈管学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590943
[Presentation] レーザーマイクロダイセクション法を用いた心筋構成細胞の選択的遺伝子発現解析法の開発2008
- Author(s)
  池田理望, 甲斐久史, 安岡逸, 梶本英美, 今泉勉
- Organizer
  第30回日本高血圧学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] バルサルタン長期投与は高血圧心の線維化を減少させ拡張能を改善する-心エコー法を用いた検討-.2008
- Author(s)
  甲斐久史, 今泉勉
- Organizer
  第56回日本心臓病学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] バルサルタン長期投与は高血圧心における心筋線維化を減弱し拡張能を改善する-心エコー法を用いた検討-2008
- Author(s)
  水田吉彦, 甲斐久史, 溝口みのり, 今泉勉
- Organizer
  第30回日本高血圧学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Postatal blocking of interferon-γ regresse and destabilizes advanced advanced plaque by inhibiting CD40/CD40 ligand pathway and infiarnmation in apoE-knockout mice2008
- Author(s)
  Yasuoka M, Kai H(他4名2番目)
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Simvastatin attenuates large blood pressure variability-induced aggravation of cardiac hypertrophy, but not myocardial fibrosis, by inhibiting Ras-ERK and Rho A pathways in hypertensive rats. .New cardioproteictive effects of statins-2008
- Author(s)
  Takayama N, Kai H, (他8 名2 番目)
- Organizer
  62^<nd> High Blood Pressure Research Conference 2008 and Scientific Sessions of the Council for High Blood Pressure Research
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Simvastatin attenuates large blood pressure variability-induced aggravation of cardiac hypertrophy, but not myocardial fibrosis, by inhibiting Ras-ERK and Rho A pathways in hypertensive rats. -New cardioproteictive effects of statins-2008
- Author(s)
  Takayama N, Kai H, 他8名2番目
- Organizer
  62^<nd> High Blood Pressure Research Conference 2008 and Scientific Sessions of the Council for High Blood Pressure Research
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] シンポジウム2 : "急性冠症候群に対する診断体系に向けて"動脈硬化プラーク活動性の新しい評価法-FDG-PET/CT法による検討-2008
- Author(s)
  甲斐久史
- Organizer
  第17回日本心血管インターペンション学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Simvastatin attenuates large blood pressure vafiability-induced aggravation of cardiac hypertrophy by inhibiting ERK and Rho A pathway2008
- Author(s)
  Takayama N, Kai H(他7名2番目)
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Valsartan improved myocardial fibrosis and diastolic dysfunction in hypertensive patients, preferentially in patients with severe fibrosis.2008
- Author(s)
  Mizuta Y, Kai H, (他4 名2 番目)
- Organizer
  62^<nd> High Blood Pressure Research Conference 2008 and Scientific Sessions of the Council for High Blood Pressure Research
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Role of Asymmetric Dimethylarginine in endothelial dysfunction in renal failure mice.2008
- Author(s)
  Kajimoto H, Kai H, (他3 名2 番目)
- Organizer
  62^<nd> High Blood Pressure Research Conference 2008 and Scientific Sessions of the Council for High Blood Pressure Research
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Large blood pressure variability superimposed on sustained hypertension aggravates cardiac remodeling and function via angiotensin II-mediated inflammation2008
- Author(s)
  Kudo H, Kai H(他8名2番目)
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] 肺高血圧モデルラツトにおける間葉系幹細胞をベクターとしたプロスタサイクリン遺伝子治療2008
- Author(s)
  武宮清子, 甲斐久史, 他2名2番目
- Organizer
  第56回日本心臓病学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Long-term treatment with valsartan attenuates myocardial fibrosis and improves diastolic dysfunction in hypertensive patients -The echorcardiographic assessment-2008
- Author(s)
  Mizuta Y, Kai H, 他2名2番目
- Organizer
  第30回日本心不全学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] 高用量ストロングスタチン抵抗性高LDLコレステロール血症に対するエゼチミブ隔日併用投与の有用性2008
- Author(s)
  甲斐久史
- Organizer
  第50回日本老年医学会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Blood pressure variability-induced aggravation of end-organ damages is another achievable target of hypertension treatment .Effects of angiotensin receptor blocker in animal model-2007
- Author(s)
  Kudo H, Kai H (他9 名2 番目)
- Organizer
  American Heart Association Scientific Sessions 2007
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Interferon-gamma-mediated CD40/CD40 ligand pathway activation mediates atherosclerotic plaque progression and destabilization in apoE-knockout mice.2007
- Author(s)
  Ikeda A, Kai H (他2 名2 番目)
- Organizer
  American Heart Association Scientific Sessions 2007
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Estrogen withdrawal aggravates myocardial fibrosis and diastolic dysfunction in pressure-overloaded female rats by enhancing perivascular inflammation and oxidative stress.2007
- Author(s)
  Mori T, Kai H (他6 名2 番目)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Simvastatin attenuates the large blood pressure variability-induced aggravation of cardiac hypertrophy by inhibiting ERK and Rho A2007
- Author(s)
  高山成政, 甲斐久史(他7名2番目)
- Organizer
  第11回日本心不全寧会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Valsartan attenuated myocardial fibrosis and diastolic dysfunction of hypertensive hypertrophied hearts in humans. Assessment using integrated backscatter analysis2007
- Author(s)
  Mizuta Y, Kai H(他2名2番国)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien,Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Blood pressure variability-induced aggravation of end-organ damages is another achievable target of hypertension treatment-Effects of angiotensin receptor blocker in animal model2007
- Author(s)
  Kudo H, Kai H(他6名2番目)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien,Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Blood pressure variability-induced aggravation of end-organ damages is another achievable target of hypertension treatment. Effects of angiotensin receptor blocker in animal model-2007
- Author(s)
  Kudo H, Kai H (他6 名2 番目)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Valsartan attenuated myocardial fibrosis and diastolic dysfunction of hypertensive hypertrophied hearts in humans. Assessment using integrated backscatter analysis.2007
- Author(s)
  Mizuta Y, Kai H (他2 名2 番目)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Simvastatin attenuates large blood pressure variability-induced aggravation of cardiac hypertrophy by inhibiting ERK and Rho A pathway in spontaneously hypertensive rats2007
- Author(s)
  Takayama N, Kai H(他6名2翻)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien,Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] シンバスタチンは血圧変動によるRhoA/ras-ERK系活性化抑制を介して高血圧性心肥大増悪を改善する-スタチンの新たな新保護作用2007
- Author(s)
  高山成政, 甲斐久史(他7名2番目)
- Organizer
  第30回日本高血圧学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] A crucial role of Rho/Rho-Kinase pathway in constriction and closure of human and rabbit ductus arteriosus.2007
- Author(s)
  梶本英美, 甲斐久史(他2名2番目)
- Organizer
  第15回日本血管生物医学会学術集会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Blood pressure variability-induced aggravation of end-organ damages is another achievable target of hypertension treatment-Effects of angiotensin receptor blocker in animal model-2007
- Author(s)
  Kudo H, Kai H(他9名2番目)
- Organizer
  American Heart Association Scientific Sessions 2007
- Place of Presentation
  Orlando,USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Mesenchymal stem cell-based prostacyclin synthase gene therapy for monocrotaline-induced pulmonary hypertension.2007
- Author(s)
  Takemiya K, Kai H(他II名2番目)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien,Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Mesenchymal stem cell-based prostacyclin synthase gene therapy for monocrotaline-induced pulmonary hypertension.2007
- Author(s)
  Takemiya K, Kai H (他11 名2 番目)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien, Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Estrogen Withdrawal aggravates myocardial fibrosis and diastolic dysfunction in pressure-overloaded female rats by enhancing perivascular inflammation and oxidative stress2007
- Author(s)
  Mori T, Kai H(他6名2番目)
- Organizer
  European Society of Cardiology Congress 2007
- Place of Presentation
  Wien,Austria
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Ihterferon-gamma-mediated CD40/CD40 ligand pathway activation mediates atherosclerotic plaque progression and destabilization in apoE-knockout mice.2007
- Author(s)
  Ikeda A, Kai H(他2名2番目)
- Organizer
  American Heart Association Scientific Sessions 2007
- Place of Presentation
  Orlando,USA
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] 閉経後高血圧性肥大心李モデリングにおける拡張障害の機序-E2欠乏による心筋血管周囲炎症と線維化の増悪2007
- Author(s)
  森隆宏, 甲斐久史(他5名2番目)
- Organizer
  第11回日本心不全学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-19590839
[Presentation] Within-individual day-by-day blood pressure variability during subacute stage predicts functional and long-term survival outcomes in ischemic stroke patients: Fukuoka Stroke Registry
- Author(s)
  Kenji Fukuda, Hisashi Kai, Masahiro Kamouchi, Jun Hata, Testsuo Ago, Tutomu Imaizumi, Takanari Kitazono
- Organizer
  European Society of Cardiology Congress 2014
- Place of Presentation
  スペイン　バルセロナ
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-26460756

1. IMAIZUMI Tsutomu (60148947)

# of Collaborated Projects: 7 results

# of Collaborated Products: 34 results
2. NIIYAMA Hiroshi (30309778)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
3. KAJIMOTO Hidemi (50349700)

# of Collaborated Projects: 7 results

# of Collaborated Products: 67 results
4. YASUOKA Suguru (10461435)

# of Collaborated Projects: 5 results

# of Collaborated Products: 52 results
5. ANAGAWA Takahiro (00511833)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
6. YASUKAWA Hideo (60289361)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
7. KUWAHARA Fumitaka (90279167)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
8. TAKAYAMA Narimasa (70389253)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
9. UCHIWA Hiroki (30624506)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
10. KUDO Hiroshihiroshi (10373135)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
11. KAI Hisashi (50289550)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. IKEDA Ayami (80412500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
13. ADACHI Hisashi (40212518)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
14. Fukuda Kenji (10624512)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
15. NAGATA Tsuyoshi (70289429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. MORI Takahiro (80389254)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
17. 岩元美子 (30597422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. TAKEMIYA Kiyoko (20535075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. AOKI Yuji (80597419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
20. EGASHIRA Kensuke (60260379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KOMORI Kimihiro (40225587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SUEISHI Katuo (70108710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ICHIKI Toshihiro (80311843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. YOSHIMURA Akihkio (90182815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. MINOGUCHI Shigeru (60322757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. WAKIOKA Toru (40330873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SEKI Yukihiko (00279168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. AKASHI Hidetoshi (80184084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. MUROHARA Toyoaki (90299503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
30. TAHARA Nobuhiro (10320186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. KATAOKA Yasufumi (70136513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
32. 北園孝成 (70284487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
33. 鴨打正浩 (80346783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. 大坪素秋 (10211799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 徳田圭亮 (80320191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 翁徳仁 (10412503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
37. 加藤宏司 (70279165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
38. KOGA Mitsuhisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
39. HIROOKA Yoshitaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
40. NISHIDA Ken-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. MATSUMOTO Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. JAMES Ihle

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. IHLE James

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. OOBOSHI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. KIMURA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. SHIBATA Rei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. OKUDA Seiya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 加藤誠也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 福田治久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 土橋卓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 青木浩樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 前村浩二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 上田誠二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAI Hisashi 甲斐 久史

Research Projects

Research Products

Co-Researchers

バイオマーカーを用いた新規サルコペニア指標の心疾患サルコペニア悪化・予後予測能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Risk Stratification of Cerebral Bleeding during Antithrombotic TherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Key Molecule of Aggravation of Hypertensive Organ Damage by Large Blood Pressure VariabilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the Crosstalk between Myocardium and Vasculature:Mechanism of Prevention of Hypertension by Intervention in Prehypertensive StagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gender differences in the mechanism of hypertensive organ damage in the heartPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of inflammation in hypertensive organ damagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

KAI Hisashi 甲斐久史